Mark E. Stearns - Related publications

Drexel University College of Medicine, Philadelphia, PA, United States 
Cell Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Yang Y, Yan T, Han Q, Zhang M, Zhang Y, Luo Y, Wei L, Li P, Wang E. ZNF326 promotes colorectal cancer epithelial-mesenchymal transition. Pathology, Research and Practice. 225: 153554. PMID 34332402 DOI: 10.1016/j.prp.2021.153554   
2021 Malireddi RKS, Karki R, Sundaram B, Kancharana B, Lee S, Samir P, Kanneganti TD. Inflammatory Cell Death, PANoptosis, Mediated by Cytokines in Diverse Cancer Lineages Inhibits Tumor Growth. Immunohorizons. 5: 568-580. PMID 34290111 DOI: 10.4049/immunohorizons.2100059   
2021 Zhao Y, Hu S, Zhang J, Cai Z, Wang S, Liu M, Dai J, Gao Y. Glucoside xylosyltransferase 2 as a diagnostic and prognostic marker in gastric cancer via comprehensive analysis. Bioengineered. 12: 5641-5654. PMID 34506251 DOI: 10.1080/21655979.2021.1967067   
2021 Chen CL, Meng E, Wu ST, Lai HF, Lu YS, Yang MH, Tsao CW, Kao CC, Chiu YL. Targeting May Result in Enhanced Migration of Cancer Cells in Bladder Carcinoma. Cancers. 13. PMID 34503284 DOI: 10.3390/cancers13174474   
2021 Hernandez R, LaPorte KM, Hsiung S, Santos Savio A, Malek TR. High-dose IL-2/CD25 fusion protein amplifies vaccine-induced CD4 and CD8 neoantigen-specific T cells to promote antitumor immunity. Journal For Immunotherapy of Cancer. 9. PMID 34475132 DOI: 10.1136/jitc-2021-002865   
2021 Su X, Xu Y, Fox GC, Xiang J, Kwakwa KA, Davis JL, Belle JI, Lee WC, Wong WH, Fontana F, Hernandez-Aya L, Kobayashi T, Tomasson HM, Su J, Bakewell SJ, et al. Breast cancer derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment. The Journal of Clinical Investigation. PMID 34520398 DOI: 10.1172/JCI145296   
2021 Yuan G, Chen B, Meng Y, Lu J, Shi X, Hu A, Hu Y, Wang D. Role of the CXCR3‑mediated TLRs/MyD88 signaling pathway in promoting the development of hepatitis B into cirrhosis and liver cancer. Molecular Medicine Reports. 24. PMID 34435646 DOI: 10.3892/mmr.2021.12378   
2021 Lothong M, Sakares W, Rojsitthisak P, Tanikawa C, Matsuda K, Yodsurang V. Collagen XVII inhibits breast cancer cell proliferation and growth through deactivation of the AKT/mTOR signaling pathway. Plos One. 16: e0255179. PMID 34293053 DOI: 10.1371/journal.pone.0255179   
2021 Gao S, Hsu TW, Li MO. Immunity beyond cancer cells: perspective from tumor tissue. Trends in Cancer. PMID 34305041 DOI: 10.1016/j.trecan.2021.06.007   
2021 Sato A, Rahman NIA, Shimizu A, Ogita H. Cell-to-cell contact-mediated regulation of tumor behavior in the tumor microenvironment. Cancer Science. PMID 34420253 DOI: 10.1111/cas.15114   
2021 Wingert S, Reusch U, Knackmuss S, Kluge M, Damrat M, Pahl J, Schniegler-Mattox U, Mueller T, Fucek I, Ellwanger K, Tesar M, Haneke T, Koch J, Treder M, Fischer W, et al. Preclinical evaluation of AFM24, a novel CD16A-specific innate immune cell engager targeting EGFR-positive tumors. Mabs. 13: 1950264. PMID 34325617 DOI: 10.1080/19420862.2021.1950264   
2021 Xiong C, Yan B, Xia S, Yu F, Zhao J, Bai H. Tilianin inhibits the human ovarian cancer (PA-1) cell proliferation via blocking cell cycle, inducing apoptosis and inhibiting JAK2/STAT3 signaling pathway. Saudi Journal of Biological Sciences. 28: 4900-4907. PMID 34466064 DOI: 10.1016/j.sjbs.2021.06.033   
2021 Ding X, Chen T, Shi Q, Nan P, Wang X, Xie D, Li J. INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling. Experimental Cell Research. 112826. PMID 34508742 DOI: 10.1016/j.yexcr.2021.112826   
2021 Hafez DE, Hafez E, Eddiasty I, Shih SP, Chien LC, Hong YJ, Lin HY, Keeton AB, Piazza GA, Abdel-Halim M, Abadi AH. Novel thiazolidine derivatives as potent selective pro-apoptotic agents. Bioorganic Chemistry. 114: 105143. PMID 34328854 DOI: 10.1016/j.bioorg.2021.105143   
2021 Tran LL, Dang T, Thomas R, Rowley DR. ELF3 mediates IL-1α induced differentiation of mesenchymal stem cells to inflammatory iCAFs. Stem Cells (Dayton, Ohio). PMID 34520582 DOI: 10.1002/stem.3455   
2021 Okada N, Sugiyama K, Shichi S, Shirai Y, Goto K, Sakane F, Kitamura H, Taketomi A. Combination therapy for hepatocellular carcinoma with diacylglycerol kinase alpha inhibition and anti-programmed cell death-1 ligand blockade. Cancer Immunology, Immunotherapy : Cii. PMID 34482409 DOI: 10.1007/s00262-021-03041-z   
2021 Shi C, Weng M, Zhu H, Guo Y, Xu D, Jin H, Wei B, Cao Z. NUDCD1 knockdown inhibits the proliferation, migration, and invasion of pancreatic cancer via the EMT process. Aging. 13. PMID 34325402 DOI: 10.18632/aging.203276   
2021 Qiao Q, Bai R, Song W, Gao H, Zhang M, Lu J, Hong M, Zhang X, Sun P, Zhang Q, Zhao P. Human α-Defensin 5 suppressed Colon Cancer Growth by Targeting PI3K pathway. Experimental Cell Research. 112809. PMID 34487729 DOI: 10.1016/j.yexcr.2021.112809   
2021 Zhou L, Xie X. RNA-binding protein CELF2 inhibits breast cancer cell invasion and angiogenesis by downregulating NFATc1. Experimental and Therapeutic Medicine. 22: 898. PMID 34257711 DOI: 10.3892/etm.2021.10330   
2021 Zhou L, Xie X. RNA-binding protein CELF2 inhibits breast cancer cell invasion and angiogenesis by downregulating NFATc1. Experimental and Therapeutic Medicine. 22: 898. PMID 34257711 DOI: 10.3892/etm.2021.10330   
2021 Scheurlen KM, Snook DL, Gardner SA, Eichenberger MR, Galandiuk S. Macrophage Differentiation and Polarization into an M2-Like Phenotype using a Human Monocyte-Like THP-1 Leukemia Cell Line. Journal of Visualized Experiments : Jove. PMID 34398156 DOI: 10.3791/62652   
2021 Eom SY, Kim MM. The inhibitory effect of Agrimonia Pilosa methanolic extract on matrix metalloproteinases in HT1080 cells. Journal of Food Biochemistry. e13894. PMID 34374443 DOI: 10.1111/jfbc.13894   
2021 Lai F, Zhang H, Xu B, Xie Y, Yu H. Long non-coding RNA NBR2 suppresses the progress of colorectal cancer in vitro and in vivo by regulating the polarization of TAM. Bioengineered. 12: 5462-5475. PMID 34506209 DOI: 10.1080/21655979.2021.1958558   
2021 Yan L, He Z, Li W, Liu N, Gao S. P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway. Cell Cycle (Georgetown, Tex.). 1-15. PMID 34382920 DOI: 10.1080/15384101.2021.1963910   
2021 Fan Y, Sun Q, Li X, Feng J, Ao Z, Li X, Wang J. Substrate Stiffness Modulates the Growth, Phenotype, and Chemoresistance of Ovarian Cancer Cells. Frontiers in Cell and Developmental Biology. 9: 718834. PMID 34504843 DOI: 10.3389/fcell.2021.718834   
2021 Liu J, Tian Z, Liu T, Wen D, Ma Z, Liu Y, Zhu J. CHSY1 is upregulated and acts as tumor promotor in gastric cancer through regulating cell proliferation, apoptosis, and migration. Cell Cycle (Georgetown, Tex.). 1-14. PMID 34412565 DOI: 10.1080/15384101.2021.1963553   
2021 Mu Q, Najafi M. Modulation of the tumor microenvironment (TME) by melatonin. European Journal of Pharmacology. 907: 174365. PMID 34302814 DOI: 10.1016/j.ejphar.2021.174365   
2021 Li H, Meng Y, Ma S, Dang C, Xue L. VALD-3 inhibits proliferation and induces apoptosis of colorectal cancer cells via upregulating tumor suppressor activity of p53 to inhibit Wnt/β-catenin signal pathway. Anti-Cancer Drugs. PMID 34419958 DOI: 10.1097/CAD.0000000000001116   
2021 Ma B, Ran R, Liao HY, Zhang HH. The paradoxical role of matrix metalloproteinase-11 in cancer. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 141: 111899. PMID 34346316 DOI: 10.1016/j.biopha.2021.111899   
2021 Sun L, Kees T, Almeida AS, Liu B, He XY, Ng D, Han X, Spector DL, McNeish IA, Gimotty P, Adams S, Egeblad M. Activating a collaborative innate-adaptive immune response to control metastasis. Cancer Cell. PMID 34478639 DOI: 10.1016/j.ccell.2021.08.005   
2021 Liang YH, Wu JM, Teng JW, Hung E, Wang HS. Embelin downregulated cFLIP in breast cancer cell lines facilitate anti-tumor effect of IL-1β-stimulated human umbilical cord mesenchymal stem cells. Scientific Reports. 11: 14720. PMID 34282169 DOI: 10.1038/s41598-021-94006-w   
2021 Touboul R, Zaravinos A, Bonavida B. Defective Natural Killer Cells in Melanoma: Role of NKG2D in Pathogenesis and Immunotherapy. Critical Reviews in Immunology. 41: 45-76. PMID 34348002 DOI: 10.1615/CritRevImmunol.2021037186   
2021 Rhyner Agocs G, Assarzadegan N, Kirsch R, Dawson H, Galván JA, Lugli A, Zlobec I, Berger MD. LAG-3 Expression Predicts Outcome in Stage II Colon Cancer. Journal of Personalized Medicine. 11. PMID 34442393 DOI: 10.3390/jpm11080749   
2021 Huang TH, Mokgautsi N, Huang YJ, Wu ATH, Huang HS. Comprehensive Omics Analysis of a Novel Small-Molecule Inhibitor of Chemoresistant Oncogenic Signatures in Colorectal Cancer Cell with Antitumor Effects. Cells. 10. PMID 34440739 DOI: 10.3390/cells10081970   
2021 Tan W, Thi-Quynh Duong M, Zuo C, Qin Y, Zhang Y, Guo Y, Hong Y, Zheng JH, Min JJ. Targeting of pancreatic cancer cells and stromal cells using engineered oncolytic Salmonella typhimurium. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 34400328 DOI: 10.1016/j.ymthe.2021.08.023   
2021 de Miranda MC, Ferreira ADF, de Melo MIA, Kunrath-Lima M, Goes AM, Rodrigues MA, Gomes DA, Faria JAQA. Adipose-derived stem/stromal cell secretome modulates breast cancer cell proliferation and differentiation state towards aggressiveness. Biochimie. 191: 69-77. PMID 34454978 DOI: 10.1016/j.biochi.2021.08.010   
2021 Helena J, Joubert A, Mabeta P, Coetzee M, Lakier R, Mercier A. Intracellular Signaling Responses Induced by Radiation within an In Vitro Bone Metastasis Model after Pre-Treatment with an Estrone Analogue. Cells. 10. PMID 34440874 DOI: 10.3390/cells10082105   
2021 Fu X, He Y, Li M, Huang Z, Najafi M. Targeting of the tumor microenvironment by curcumin. Biofactors (Oxford, England). PMID 34375483 DOI: 10.1002/biof.1776   
2021 Chen R, Sheng C, Ma R, Zhang L, Yang L, Chen Y. PLAC1 is an independent predictor of poor survival, and promotes cell proliferation and invasion in cervical cancer. Molecular Medicine Reports. 24. PMID 34523695 DOI: 10.3892/mmr.2021.12440   
2021 Zerbib E, Arif T, Shteinfer-Kuzmine A, Chalifa-Caspi V, Shoshan-Barmatz V. VDAC1 Silencing in Cancer Cells Leads to Metabolic Reprogramming That Modulates Tumor Microenvironment. Cancers. 13. PMID 34200480 DOI: 10.3390/cancers13112850   
2021 Hintz HM, Snyder KM, Wu J, Hullsiek R, Dahlvang JD, Hart GT, Walcheck B, LeBeau AM. Simultaneous engagement of tumor and stroma targeting antibodies by engineered NK-92 cells expressing CD64 controls prostate cancer growth. Cancer Immunology Research. PMID 34452926 DOI: 10.1158/2326-6066.CIR-21-0178   
2021 Du R, Zhao P, Wu S, Gao Y, Wu R, Yang M, Song W, Gao H. Sendeng-4 Suppressed Melanoma Growth by Induction of Autophagy and Apoptosis. Evidence-Based Complementary and Alternative Medicine : Ecam. 2021: 5519973. PMID 34475961 DOI: 10.1155/2021/5519973   
2021 Zhai D, Xu Y, Abdelghany L, Zhang X, Liang J, Zhang S, Guo C, Li TS. Hydrostatic pressure stabilizes HIF‑1α expression in cancer cells to protect against oxidative damage during metastasis. Oncology Reports. 46. PMID 34368876 DOI: 10.3892/or.2021.8162   
2021 Madsen NH, Nielsen BS, Nhat SL, Skov S, Gad M, Larsen J. Monocyte Infiltration and Differentiation in 3D Multicellular Spheroid Cancer Models. Pathogens (Basel, Switzerland). 10. PMID 34451433 DOI: 10.3390/pathogens10080969   
2021 Yamaguchi M, Takagi K, Sato M, Sato A, Miki Y, Onodera Y, Miyashita M, Sasano H, Suzuki T. Androgens enhance the ability of intratumoral macrophages to promote breast cancer progression. Oncology Reports. 46. PMID 34278480 DOI: 10.3892/or.2021.8139   
2021 Zhang D, Zhu Y, Su Y, Yu M, Xu X, Wang C, Zhang S, Xia L. Taurochenodeoxycholic acid inhibits the proliferation and invasion of gastric cancer and induces its apoptosis. Journal of Food Biochemistry. e13866. PMID 34278593 DOI: 10.1111/jfbc.13866   
2021 Zhang D, Zhu Y, Su Y, Yu M, Xu X, Wang C, Zhang S, Xia L. Taurochenodeoxycholic acid inhibits the proliferation and invasion of gastric cancer and induces its apoptosis. Journal of Food Biochemistry. e13866. PMID 34278593 DOI: 10.1111/jfbc.13866   
2021 Liu C, Zhang W, Wang J, Si T, Xing W. Tumor associated macrophages derived TGF-β promotes colorectal cancer progression through HIF1-TRIB3 signaling. Cancer Science. PMID 34375482 DOI: 10.1111/cas.15101   
2021 Ha J, Lee S, Park J, Seo J, Kang E, Yoon H, Kim BR, Lee HK, Ryu SE, Cho S. Identification of a novel inhibitor of liver cancer cell invasion and proliferation through regulation of Akt and Twist1. Scientific Reports. 11: 16765. PMID 34408201 DOI: 10.1038/s41598-021-95933-4   
2021 Itashiki Y, Harada K, Takenawa T, Ferdous T, Ueyama Y, Mishima K. Antitumor effects of bevacizumab in combination with fluoropyrimidine drugs on human oral squamous cell carcinoma. Oncology Letters. 22: 730. PMID 34429770 DOI: 10.3892/ol.2021.12991