Brant E. Isakson - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Vasculature, Myoendothelial Junctions
Website:
https://www.cvrc.virginia.edu/Isakson/index.html

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wenceslau CF, McCarthy CG, Earley S, England SK, Filosa JA, Goulopoulou S, Gutterman DD, Isakson BE, Kanagy NL, Martinez-Lemus LA, Sonkusare SK, Thakore P, Trask AJ, Watts SW, Webb RC. Guidelines for the measurement of vascular function and structure in isolated arteries and veins. American Journal of Physiology. Heart and Circulatory Physiology. PMID 33989082 DOI: 10.1152/ajpheart.01021.2020  0.32
2021 Daneva Z, Marziano C, Ottolini M, Chen YL, Baker TM, Kuppusamy M, Zhang A, Ta HQ, Reagan CE, Mihalek AD, Kasetti RB, Shen Y, Isakson BE, Minshall RD, Zode GS, et al. Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33879616 DOI: 10.1073/pnas.2023130118  0.32
2021 Maier-Begandt D, Comstra HS, Molina SA, Krüger N, Ruddiman CA, Chen YL, Chen X, Biwer LA, Johnstone SR, Lohman AW, Good ME, DeLalio LJ, Hong K, Bacon HM, Yan Z, ... ... Isakson BE, et al. A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability. Science Signaling. 14. PMID 33653920 DOI: 10.1126/scisignal.aba2940  0.88
2021 Good ME, Young A, Wolpe AG, Ma M, Johnstone SR, Hall PJ, Duffy CK, Aronovitz M, Martin G, Blanton RM, Leitinger N, Wolf MJ, Isakson BE. Endothelial Pannexin 1 Regulates Cardiac Response to Myocardial Infarction. Circulation Research. PMID 33641341 DOI: 10.1161/CIRCRESAHA.120.317272  0.88
2021 Wolpe AG, Ruddiman CA, Hall PJ, Isakson BE. Polarized Proteins in Endothelium and Their Contribution to Function. Journal of Vascular Research. 1-27. PMID 33503620 DOI: 10.1159/000512618  0.48
2020 Bories GF, Yeudall S, Serbulea V, Fox TE, Isakson BE, Leitinger N. Macrophage metabolic adaptation to heme detoxification involves CO-dependent activation of the pentose phosphate pathway. Blood. PMID 32556090 DOI: 10.1182/Blood.2020004964  0.44
2020 Swayne LA, Johnstone SR, Ng CS, Sanchez-Arias JC, Good ME, Penuela S, Lohman AW, Wolpe AG, Laubach VE, Koval M, Isakson BE. Consideration of Pannexin 1 channels in COVID-19 pathology and treatment. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32519892 DOI: 10.1152/Ajplung.00146.2020  0.88
2020 DeLalio LJ, Masati E, Mendu S, Ruddiman CA, Yang Y, Johnstone SR, Milstein JA, Keller TCS, Weaver RB, Guagliardo NA, Best AK, Ravichandran KS, Bayliss DA, Sequeira-Lopez MLS, Sonkusare SN, ... ... Isakson BE, et al. PANNEXIN 1 CHANNELS IN RENIN-EXPRESSING CELLS INFLUENCE RENIN SECRETION AND BLOOD PRESSURE HOMEOSTASIS. Kidney International. PMID 32446934 DOI: 10.1016/J.Kint.2020.04.041  0.76
2020 Yang Y, Delalio LJ, Best AK, Macal E, Milstein J, Donnelly I, Miller AM, McBride M, Shu X, Koval M, Isakson BE, Johnstone SR. Endothelial Pannexin 1 Channels Control Inflammation by Regulating Intracellular Calcium. Journal of Immunology (Baltimore, Md. : 1950). PMID 32312847 DOI: 10.4049/Jimmunol.1901089  0.76
2020 Garcia V, Park EJ, Siragusa M, Frohlich F, Haque MM, Pascale JV, Heberlein KR, Isakson BE, Stuehr DJ, Sessa WC. Unbiased proteomics identifies plasminogen activator inhibitor-1 as a negative regulator of endothelial nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. PMID 32300005 DOI: 10.1073/Pnas.1918761117  0.48
2020 Biwer LA, Askew-Page HR, Hong K, Milstein J, Johnstone SR, Macal E, Good ME, Bagher P, Sonkusare S, Isakson BE. Endothelial calreticulin deletion impairs endothelial function in aged mice. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32196361 DOI: 10.1152/Ajpheart.00586.2019  0.88
2020 McCallinhart PE, Biwer LA, Clark OE, Isakson BE, Lilly B, Trask AJ. Myoendothelial Junctions of Mature Coronary Vessels Express Notch Signaling Proteins. Frontiers in Physiology. 11: 29. PMID 32116749 DOI: 10.1096/Fasebj.2020.34.S1.05120  0.6
2020 Ottolini M, Hong K, Cope EL, Daneva Z, DeLalio LJ, Sokolowski JD, Marziano C, Nguyen NY, Altschmied J, Haendeler J, Johnstone SR, Kalani MY, Park MS, Patel RP, Liedtke W, ... Isakson BE, et al. Local Peroxynitrite Impairs Endothelial TRPV4 Channels and Elevates Blood Pressure in Obesity. Circulation. PMID 32008372 DOI: 10.1161/Circulationaha.119.043385  0.76
2020 Leo F, Hutzler B, Ruddiman CA, Isakson BE, Cortese-Krott MM. Cellular microdomains for nitric oxide signaling in endothelium and red blood cells. Nitric Oxide : Biology and Chemistry. 96: 44-53. PMID 31911123 DOI: 10.1016/J.Niox.2020.01.002  0.4
2019 Krüger N, Biwer LA, Good ME, Ruddiman CA, Wolpe AG, DeLalio LJ, Murphy S, Macal EH, Ragolia L, Serbulea V, Best AK, Leitinger N, Harris TE, Sonkusare SK, Gödecke A, ... Isakson BE, et al. Loss of Endothelial FTO Antagonizes Obesity-Induced Metabolic and Vascular Dysfunction. Circulation Research. PMID 31801409 DOI: 10.1161/Circresaha.119.315531  0.88
2019 Corliss BA, Delalio LJ, Stevenson Keller TC, Keller AS, Keller DA, Corliss BH, Beers JM, Peirce SM, Isakson BE. Vascular Expression of Hemoglobin Alpha in Antarctic Icefish Supports Iron Limitation as Novel Evolutionary Driver. Frontiers in Physiology. 10: 1389. PMID 31780954 DOI: 10.3389/Fphys.2019.01389  0.76
2019 Good ME, Musante L, La Salvia S, Howell NL, Carey RM, Le TH, Isakson BE, Erdbrügger U. Circulating Extracellular Vesicles in Normotension Restrain Vasodilation in Resistance Arteries. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11913. PMID 31760883 DOI: 10.1161/Hypertensionaha.119.13363  0.88
2019 Shu XH, Ruddiman CA, Keller TS, Keller AS, Yang Y, Good ME, Best AK, Columbus L, Isakson BE. Heterocellular Contact Can Dictate Arterial Function. Circulation Research. PMID 30900949 DOI: 10.1161/Circresaha.118.313926  0.88
2019 DeLalio LJ, Billaud M, Ruddiman CA, Johnstone SR, Butcher JT, Wolpe AG, Jin X, Keller TCS, Keller AS, Rivière T, Good ME, Best AK, Lohman AW, Swayne LA, Penuela S, ... ... Isakson BE, et al. Constitutive SRC-mediated phosphorylation of pannexin 1 at tyrosine 198 occurs at the plasma membrane. The Journal of Biological Chemistry. PMID 30814251 DOI: 10.1074/Jbc.Ra118.006982  0.88
2018 Artamonov MV, Sonkusare SK, Good ME, Momotani K, Eto M, Isakson BE, Le TH, Cope EL, Derewenda ZS, Derewenda U, Somlyo AV. RSK2 contributes to myogenic vasoconstriction of resistance arteries by activating smooth muscle myosin and the Na/H exchanger. Science Signaling. 11. PMID 30377223 DOI: 10.1126/Scisignal.Aar3924  0.88
2018 Brown IAM, Diederich L, Good ME, DeLalio LJ, Murphy SA, Cortese-Krott MM, Hall JL, Le TH, Isakson BE. Vascular Smooth Muscle Remodeling in Conductive and Resistance Arteries in Hypertension. Arteriosclerosis, Thrombosis, and Vascular Biology. 38: 1969-1985. PMID 30354262 DOI: 10.1161/Atvbaha.118.311229  0.88
2018 Lechauve C, Butcher JT, Freiwan A, Biwer LA, Keith JM, Good ME, Ackerman H, Tillman HS, Kiger L, Isakson BE, Weiss MJ. Endothelial cell α-globin and its molecular chaperone α-hemoglobin-stabilizing protein regulate arteriolar contractility. The Journal of Clinical Investigation. PMID 30295646 DOI: 10.1172/Jci99933  0.88
2018 Good ME, Isakson BE. "Yin and Yang" for Notch Signaling in the Mature Vasculature. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30265155 DOI: 10.1152/Ajpheart.00626.2018  0.88
2018 Suarez-Martinez AD, Peirce SM, Isakson BE, Nice M, Wang J, Lounsbury KM, Scallan JP, Murfee WL. Induction of Microvascular Network Growth in the Mouse Mesentery. Microcirculation (New York, N.Y. : 1994). e12502. PMID 30178505 DOI: 10.1111/Micc.12502  0.44
2018 DeLalio LJ, Keller AS, Chen J, Boyce AKJ, Artamonov M, Askew-Page HR, Keller TCS, Johnstone SR, Weaver RB, Good ME, Murphy S, Best AK, Mintz EL, Penuela S, Greenwood I, ... ... Isakson BE, et al. Interaction Between Pannexin 1 and Caveolin-1 in Smooth Muscle Can Regulate Blood Pressure. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 30026274 DOI: 10.1161/Atvbaha.118.311290  0.88
2018 Keller AS, Keller TCS, DeLalio LJ, Shahab G, Yang Y, Murphy S, Shu X, Isakson BE. Replacement Therapies in Metabolic Disease. Current Pharmaceutical Biotechnology. PMID 29921204 DOI: 10.2174/1389201019666180619151413  0.76
2018 Molica F, Figueroa XF, Kwak BR, Isakson BE, Gibbins JM. Connexins and Pannexins in Vascular Function and Disease. International Journal of Molecular Sciences. 19. PMID 29874791 DOI: 10.3390/Ijms19061663  0.4
2018 Diederich L, Suvorava T, Sansone R, Keller TCS, Barbarino F, Sutton TR, Kramer CM, Lückstädt W, Isakson BE, Gohlke H, Feelisch M, Kelm M, Cortese-Krott MM. On the Effects of Reactive Oxygen Species and Nitric Oxide on Red Blood Cell Deformability. Frontiers in Physiology. 9: 332. PMID 29867516 DOI: 10.3389/Fphys.2018.00332  0.32
2018 Good ME, Chiu YH, Poon IKH, Jaffe IZ, Bayliss DA, Isakson BE, Ravichandran KS. Response by Good et al to Letter Regarding Article, "Pannexin-1 Channels as an Unexpected New Target of the Antihypertensive Drug Spironolactone". Circulation Research. 122: e88-e89. PMID 29798905 DOI: 10.1161/Circresaha.118.313080  0.88
2018 Sharma AK, Charles EJ, Zhao Y, Narahari AK, Baderdinni PK, Good ME, Lorenz UM, Kron IL, Bayliss DA, Ravichandran KS, Isakson BE, Laubach VE. Pannexin 1 channels on endothelial cells mediate vascular inflammation during lung ischemia-reperfusion injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29745255 DOI: 10.1152/Ajplung.00004.2018  0.88
2018 Haskins RM, Nguyen AT, Alencar GF, Billaud M, Kelly-Goss MR, Good ME, Bottermann K, Klibanov AL, French BA, Harris TE, Peirce SM, Isakson BE, Owens GK. Klf4 has an unexpected protective role in perivascular cells within the microvasculature. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29631369 DOI: 10.1152/Ajpheart.00084.2018  0.88
2018 Johnstone SR, Isakson BE. 'Gaps' in targeted ischaemic injury therapies in ST-elevation myocardial infarction. Heart (British Cardiac Society). PMID 29602882 DOI: 10.1136/Heartjnl-2018-313084  0.52
2018 Good ME, Eucker SA, Li J, Bacon HM, Lang SM, Butcher JT, Johnson TJ, Gaykema RP, Patel MK, Zuo Z, Isakson BE. Endothelial cell Pannexin1 modulates severity of ischemic stroke by regulating cerebral inflammation and myogenic tone. Jci Insight. 3. PMID 29563335 DOI: 10.1172/Jci.Insight.96272  0.88
2018 Hong K, Cope EL, DeLalio LJ, Marziano C, Isakson BE, Sonkusare SK. TRPV4 (Transient Receptor Potential Vanilloid 4) Channel-Dependent Negative Feedback Mechanism Regulates Gq Protein-Coupled Receptor-Induced Vasoconstriction. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29301784 DOI: 10.1161/Atvbaha.117.310038  0.76
2017 Marziano C, Hong K, Cope EL, Kotlikoff MI, Isakson BE, Sonkusare SK. Nitric Oxide-Dependent Feedback Loop Regulates Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Cooperativity and Endothelial Function in Small Pulmonary Arteries. Journal of the American Heart Association. 6. PMID 29275372 DOI: 10.1161/Jaha.117.007157  0.48
2017 Good ME, Chiu YH, Poon IK, Medina CB, Butcher JT, Mendu SK, DeLalio LJ, Lohman AW, Leitinger N, Barrett EJ, Lorenz UM, Desai BN, Jaffe IZ, Bayliss D, Isakson BE, et al. Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone. Circulation Research. PMID 29237722 DOI: 10.1161/Circresaha.117.312380  0.88
2017 Biwer LA, Good ME, Hong K, Patel RK, Agrawal N, Looft-Wilson R, Sonkusare SK, Isakson BE. Non-Endoplasmic Reticulum-Based Calr (Calreticulin) Can Coordinate Heterocellular Calcium Signaling and Vascular Function. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29122814 DOI: 10.1161/Atvbaha.117.309886  0.88
2017 Biwer LA, Lechauve C, Vanhoose S, Weiss MJ, Isakson BE. A Cell Culture Model of Resistance Arteries. Journal of Visualized Experiments : Jove. PMID 28930992 DOI: 10.3791/55992  0.6
2017 Keller AS, Diederich L, Panknin C, DeLalio LJ, Drake JC, Sherman R, Jackson EK, Yan Z, Kelm M, Cortese-Krott MM, Isakson BE. Possible roles for ATP release from RBCs exclude the cAMP-mediated Panx1 pathway. American Journal of Physiology. Cell Physiology. ajpcell.00178.2017. PMID 28855161 DOI: 10.1152/Ajpcell.00178.2017  0.76
2017 DeLalio LJ, Isakson BE. ZP1609/Danegaptide and mitochondrial connexin hemichannels: a harbinger for peptide drug design. British Journal of Pharmacology. PMID 28567717 DOI: 10.1111/Bph.13891  0.76
2017 Keller A, Isakson B. The evolving role of diverse gaseous transmitters mediating heterocellular communication within the vasculature. Antioxidants & Redox Signaling. PMID 28288516 DOI: 10.1089/ars.2017.7059  0.4
2017 Durgin BG, Cherepanova OA, Gomez D, Karaoli T, Alencar GF, Butcher JT, Zhou YQ, Bendeck MP, Isakson BE, Owens GK, Connelly JJ. Smooth muscle cell-specific deletion of Col15a1 unexpectedly leads to impaired development of advanced atherosclerotic lesions. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00029.2017. PMID 28283548 DOI: 10.1152/Ajpheart.00029.2017  0.32
2017 Genet N, Billaud M, Rossignol R, Dubois M, Gillibert-Duplantier J, Isakson BE, Marthan R, Savineau JP, Guibert C. Signaling Pathways Linked to Serotonin-Induced Superoxide Anion Production: A Physiological Role for Mitochondria in Pulmonary Arteries. Frontiers in Physiology. 8: 76. PMID 28232807 DOI: 10.3389/Fphys.2017.00076  0.68
2017 Begandt D, Good ME, Keller AS, DeLalio LJ, Rowley C, Isakson BE, Figueroa XF. Pannexin channel and connexin hemichannel expression in vascular function and inflammation. Bmc Cell Biology. 18: 2. PMID 28124621 DOI: 10.1186/S12860-016-0119-3  0.88
2017 Good ME, Poon IK, Chiu Y, Butcher JT, DeLalio LJ, Mendu S, Jaffe IZ, Leitinger N, Desai BN, Bayliss DA, Ravichandran KS, Isakson BE. Spironolactone can act on pannexin1 channels in smooth muscle cells to regulate vasoconstriction and blood pressure The Faseb Journal. 31. DOI: 10.1096/Fasebj.31.1_Supplement.833.1  0.88
2016 Keller TC, Butcher JT, Broseghini-Filho GB, Marziano C, DeLalio LJ, Rogers S, Ning B, Martin JN, Chechova S, Cabot M, Shu X, Best AK, Good ME, Simão Padilha A, Purdy M, ... ... Isakson BE, et al. Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (HbαX). Hypertension (Dallas, Tex. : 1979). PMID 27802421 DOI: 10.1161/Hypertensionaha.116.08171  0.88
2016 Liu S, DeLalio LJ, Isakson BE, Wang TT. AXL-Mediated Productive Infection of Human Endothelial Cells by Zika Virus. Circulation Research. PMID 27650556 DOI: 10.1161/Circresaha.116.309866  0.76
2016 Naresh NK, Butcher JT, Lye RJ, Chen X, Isakson BE, Gan LM, Kramer CM, Annex BH, Epstein FH. Cardiovascular magnetic resonance detects the progression of impaired myocardial perfusion reserve and increased left-ventricular mass in mice fed a high-fat diet. Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society For Cardiovascular Magnetic Resonance. 18: 53. PMID 27609091 DOI: 10.1186/S12968-016-0273-Y  0.32
2016 Kauffenstein G, Tamareille S, Prunier F, Roy C, Ayer A, Toutain B, Billaud M, Isakson BE, Grimaud L, Loufrani L, Rousseau P, Abraham P, Procaccio V, Monyer H, de Wit C, et al. Central Role of P2Y6 UDP Receptor in Arteriolar Myogenic Tone. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27255725 DOI: 10.1161/Atvbaha.116.307739  0.68
2016 Good ME, Begandt D, DeLalio LJ, Johnstone SR, Isakson BE. Small Interfering RNA-Mediated Connexin Gene Knockdown in Vascular Endothelial and Smooth Muscle Cells. Methods in Molecular Biology (Clifton, N.J.). 1437: 71-82. PMID 27207287 DOI: 10.1007/978-1-4939-3664-9_5  0.88
2016 Biwer LA, Taddeo EP, Kenwood BM, Hoehn KL, Straub AC, Isakson BE. Two functionally distinct pools of eNOS in endothelium are facilitated by myoendothelial junction lipid composition. Biochimica Et Biophysica Acta. 1861: 671-9. PMID 27106139 DOI: 10.1016/J.Bbalip.2016.04.014  0.6
2016 Ivanov S, Scallan JP, Kim KW, Werth K, Johnson MW, Saunders BT, Wang PL, Kuan EL, Straub AC, Ouhachi M, Weinstein EG, Williams JW, Briseño C, Colonna M, Isakson BE, et al. CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability. The Journal of Clinical Investigation. PMID 26999610 DOI: 10.1172/Jci84518  0.48
2016 Biwer L, Isakson BE. Endoplasmic reticulum mediated signaling in cellular microdomains. Acta Physiologica (Oxford, England). PMID 26973141 DOI: 10.1111/Apha.12675  1
2016 Shankman LS, Gomez D, Cherepanova OA, Salmon M, Alencar GF, Haskins RM, Swiatlowska P, Newman AA, Greene ES, Straub AC, Isakson B, Randolph GJ, Owens GK. Corrigendum: KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nature Medicine. 22: 217. PMID 26845408 DOI: 10.1038/Nm0216-217A  0.48
2015 Adamson SE, Meher AK, Chiu YH, Sandilos JK, Oberholtzer NP, Walker NN, Hargett SR, Seaman SA, Peirce-Cottler SM, Isakson BE, McNamara CA, Keller SR, Harris TE, Bayliss DA, Leitinger N. Pannexin 1 is required for full activation of insulin-stimulated glucose uptake in adipocytes. Molecular Metabolism. 4: 610-8. PMID 26413467 DOI: 10.1016/J.Molmet.2015.06.009  0.44
2015 Shu X, Keller TC, Begandt D, Butcher JT, Biwer L, Keller AS, Columbus L, Isakson BE. Endothelial nitric oxide synthase in the microcirculation. Cellular and Molecular Life Sciences : Cmls. 72: 4561-75. PMID 26390975 DOI: 10.1007/S00018-015-2021-0  0.84
2015 Chen CH, Mayo JN, Gourdie RG, Johnstone SR, Isakson BE, Bearden SE. The Connexin 43/ZO-1 Complex Regulates Cerebral Endothelial F-actin Architecture and Migration. American Journal of Physiology. Cell Physiology. ajpcell.00155.2015. PMID 26289751 DOI: 10.1152/Ajpcell.00155.2015  0.52
2015 Lohman AW, Leskov IL, Butcher JT, Johnstone SR, Stokes TA, Begandt D, DeLalio LJ, Best AK, Penuela S, Leitinger N, Ravichandran KS, Stokes KY, Isakson BE. Pannexin 1 channels regulate leukocyte emigration through the venous endothelium during acute inflammation. Nature Communications. 6: 7965. PMID 26242575 DOI: 10.1038/Ncomms8965  0.84
2015 Good ME, Begandt D, DeLalio LJ, Keller AS, Billaud M, Isakson BE. Emerging concepts regarding pannexin 1 in the vasculature. Biochemical Society Transactions. 43: 495-501. PMID 26009197 DOI: 10.1042/Bst20150045  0.84
2015 Shankman LS, Gomez D, Cherepanova OA, Salmon M, Alencar GF, Haskins RM, Swiatlowska P, Newman AA, Greene ES, Straub AC, Isakson B, Randolph GJ, Owens GK. KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nature Medicine. 21: 628-37. PMID 25985364 DOI: 10.1038/Nm.3866  0.48
2015 Billaud M, Chiu YH, Lohman AW, Parpaite T, Butcher JT, Mutchler SM, DeLalio LJ, Artamonov MV, Sandilos JK, Best AK, Somlyo AV, Thompson RJ, Le TH, Ravichandran KS, Bayliss DA, ... Isakson BE, et al. A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells. Science Signaling. 8: ra17. PMID 25690012 DOI: 10.1126/Scisignal.2005824  0.84
2015 Naresh NK, Butcher JT, Chen X, Annex BH, Isakson BE, Epstein FH. Cardiac MR detects the progression of impaired myocardial perfusion reserve in a mouse model of obesity-related cardiomyopathy Journal of Cardiovascular Magnetic Resonance. 1-3. DOI: 10.1186/1532-429X-17-S1-P82  0.32
2014 Kavoussi PK, Heberlein K, Straub AC, Lowe GJ, Oliver JL, Smith RP, Steers WD, Annex BH, Isakson BE, Lysiak JJ. Recombinant PAI-1 therapy restores myoendothelial junctions and erectile function in PAI-1-deficient mice. Andrologia. PMID 25557984 DOI: 10.1111/and.12395  0.84
2014 Straub AC, Butcher JT, Billaud M, Mutchler SM, Artamonov MV, Nguyen AT, Johnson T, Best AK, Miller MP, Palmer LA, Columbus L, Somlyo AV, Le TH, Isakson BE. Hemoglobin α/eNOS coupling at myoendothelial junctions is required for nitric oxide scavenging during vasoconstriction. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2594-600. PMID 25278292 DOI: 10.1016/J.Niox.2014.09.126  0.84
2014 Straub AC, Zeigler AC, Isakson BE. The myoendothelial junction: connections that deliver the message. Physiology (Bethesda, Md.). 29: 242-9. PMID 24985328 DOI: 10.1152/Physiol.00042.2013  0.48
2014 Butcher JT, Johnson T, Beers J, Columbus L, Isakson BE. Hemoglobin α in the blood vessel wall. Free Radical Biology & Medicine. 73: 136-42. PMID 24832680 DOI: 10.1016/J.Freeradbiomed.2014.04.019  0.84
2014 Billaud M, Lohman AW, Johnstone SR, Biwer LA, Mutchler S, Isakson BE. Regulation of cellular communication by signaling microdomains in the blood vessel wall. Pharmacological Reviews. 66: 513-69. PMID 24671377 DOI: 10.1124/Pr.112.007351  0.88
2014 Koval M, Isakson BE, Gourdie RG. Connexins, pannexins and innexins: protein cousins with overlapping functions. Febs Letters. 588: 1185. PMID 24613922 DOI: 10.1016/j.febslet.2014.03.001  0.84
2014 Isakson BE, Thompson RJ. Pannexin-1 as a potentiator of ligand-gated receptor signaling. Channels (Austin, Tex.). 8: 118-23. PMID 24576994 DOI: 10.4161/Chan.27978  0.84
2014 Lohman AW, Isakson BE. Differentiating connexin hemichannels and pannexin channels in cellular ATP release. Febs Letters. 588: 1379-88. PMID 24548565 DOI: 10.1016/J.Febslet.2014.02.004  0.88
2014 Penuela S, Lohman AW, Lai W, Gyenis L, Litchfield DW, Isakson BE, Laird DW. Diverse post-translational modifications of the pannexin family of channel-forming proteins. Channels (Austin, Tex.). 8: 124-30. PMID 24418849 DOI: 10.4161/Chan.27422  0.88
2014 Adhikari N, Billaud M, Carlson M, Lake SP, Montaniel KR, Staggs R, Guan W, Walek D, Desir S, Isakson BE, Barocas VH, Hall JL. Vascular biomechanical properties in mice with smooth muscle specific deletion of Ndst1. Molecular and Cellular Biochemistry. 385: 225-38. PMID 24101444 DOI: 10.1007/S11010-013-1831-3  0.84
2013 Cechova S, Zeng Q, Billaud M, Mutchler S, Rudy CK, Straub AC, Chi L, Chan FR, Hu J, Griffiths R, Howell NL, Madsen K, Jensen BL, Palmer LA, Carey RM, ... ... Isakson BE, et al. Loss of collectrin, an angiotensin-converting enzyme 2 homolog, uncouples endothelial nitric oxide synthase and causes hypertension and vascular dysfunction. Circulation. 128: 1770-80. PMID 24048198 DOI: 10.1161/Circulationaha.113.003301  0.84
2012 Straub AC, Lohman AW, Billaud M, Johnstone SR, Dwyer ST, Lee MY, Bortz PS, Best AK, Columbus L, Gaston B, Isakson BE. Endothelial cell expression of haemoglobin α regulates nitric oxide signalling. Nature. 491: 473-7. PMID 23123858 DOI: 10.1038/Nature11626  0.84
2012 Wang L, Yin J, Nickles HT, Ranke H, Tabuchi A, Hoffmann J, Tabeling C, Barbosa-Sicard E, Chanson M, Kwak BR, Shin HS, Wu S, Isakson BE, Witzenrath M, de Wit C, et al. Hypoxic pulmonary vasoconstriction requires connexin 40-mediated endothelial signal conduction. The Journal of Clinical Investigation. 122: 4218-30. PMID 23093775 DOI: 10.1172/Jci59176  0.84
2012 Lohman AW, Weaver JL, Billaud M, Sandilos JK, Griffiths R, Straub AC, Penuela S, Leitinger N, Laird DW, Bayliss DA, Isakson BE. S-nitrosylation inhibits pannexin 1 channel function. The Journal of Biological Chemistry. 287: 39602-12. PMID 23033481 DOI: 10.1074/Jbc.M112.397976  0.84
2012 Billaud M, Sandilos JK, Isakson BE. Pannexin 1 in the regulation of vascular tone. Trends in Cardiovascular Medicine. 22: 68-72. PMID 22841835 DOI: 10.1016/J.Tcm.2012.06.014  0.68
2012 Johnstone SR, Billaud M, Lohman AW, Taddeo EP, Isakson BE. Posttranslational modifications in connexins and pannexins. The Journal of Membrane Biology. 245: 319-32. PMID 22739962 DOI: 10.1007/S00232-012-9453-3  0.88
2012 Lohman AW, Billaud M, Straub AC, Johnstone SR, Best AK, Lee M, Barr K, Penuela S, Laird DW, Isakson BE. Expression of pannexin isoforms in the systemic murine arterial network. Journal of Vascular Research. 49: 405-16. PMID 22739252 DOI: 10.1159/000338758  0.84
2012 Lohman AW, Billaud M, Isakson BE. Mechanisms of ATP release and signalling in the blood vessel wall. Cardiovascular Research. 95: 269-80. PMID 22678409 DOI: 10.1093/Cvr/Cvs187  0.88
2012 Johnstone SR, Kroncke BM, Straub AC, Best AK, Dunn CA, Mitchell LA, Peskova Y, Nakamoto RK, Koval M, Lo CW, Lampe PD, Columbus L, Isakson BE. MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation. Circulation Research. 111: 201-11. PMID 22652908 DOI: 10.1161/Circresaha.112.272302  0.84
2012 Montaniel KR, Billaud M, Graham C, Kim SK, Carlson M, Zeng W, Zeng O, Pan W, Isakson BE, Hall JL, Adhikari N. Smooth muscle specific deletion of Ndst1 leads to decreased vessel luminal area and no change in blood pressure in conscious mice. Journal of Cardiovascular Translational Research. 5: 274-9. PMID 22555965 DOI: 10.1007/S12265-012-9369-4  0.84
2012 Billaud M, Johnstone SR, Isakson BE. Loss of compliance in small arteries, but not in conduit arteries, after 6 weeks exposure to high fat diet. Journal of Cardiovascular Translational Research. 5: 256-63. PMID 22467359 DOI: 10.1007/S12265-012-9354-Y  0.68
2012 Heberlein KR, Han J, Straub AC, Best AK, Kaun C, Wojta J, Isakson BE. A novel mRNA binding protein complex promotes localized plasminogen activator inhibitor-1 accumulation at the myoendothelial junction. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1271-9. PMID 22383705 DOI: 10.1161/Atvbaha.112.246371  0.48
2012 Billaud M, Lohman AW, Straub AC, Parpaite T, Johnstone SR, Isakson BE. Characterization of the thoracodorsal artery: morphology and reactivity. Microcirculation (New York, N.Y. : 1994). 19: 360-72. PMID 22335567 DOI: 10.1111/J.1549-8719.2012.00172.X  0.88
2012 Looft-Wilson RC, Billaud M, Johnstone SR, Straub AC, Isakson BE. Interaction between nitric oxide signaling and gap junctions: effects on vascular function. Biochimica Et Biophysica Acta. 1818: 1895-902. PMID 21835160 DOI: 10.1016/J.Bbamem.2011.07.031  0.68
2011 Koval M, Billaud M, Straub AC, Johnstone SR, Zarbock A, Duling BR, Isakson BE. Spontaneous lung dysfunction and fibrosis in mice lacking connexin 40 and endothelial cell connexin 43. The American Journal of Pathology. 178: 2536-46. PMID 21641379 DOI: 10.1016/J.Ajpath.2011.02.045  0.68
2011 Billaud M, Lohman AW, Straub AC, Looft-Wilson R, Johnstone SR, Araj CA, Best AK, Chekeni FB, Ravichandran KS, Penuela S, Laird DW, Isakson BE. Pannexin1 regulates α1-adrenergic receptor- mediated vasoconstriction. Circulation Research. 109: 80-5. PMID 21546608 DOI: 10.1161/Circresaha.110.237594  0.88
2011 Billaud M, Ross JA, Greyson MA, Bruce AC, Seaman SA, Heberlein KR, Han J, Best AK, Peirce SM, Isakson BE. A new method for in vivo visualization of vessel remodeling using a near-infrared dye. Microcirculation (New York, N.Y. : 1994). 18: 163-71. PMID 21418375 DOI: 10.1111/J.1549-8719.2011.00085.X  0.84
2011 Straub AC, Billaud M, Johnstone SR, Best AK, Yemen S, Dwyer ST, Looft-Wilson R, Lysiak JJ, Gaston B, Palmer L, Isakson BE. Compartmentalized connexin 43 s-nitrosylation/denitrosylation regulates heterocellular communication in the vessel wall. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 399-407. PMID 21071693 DOI: 10.1161/Atvbaha.110.215939  0.84
2010 Chekeni FB, Elliott MR, Sandilos JK, Walk SF, Kinchen JM, Lazarowski ER, Armstrong AJ, Penuela S, Laird DW, Salvesen GS, Isakson BE, Bayliss DA, Ravichandran KS. Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature. 467: 863-7. PMID 20944749 DOI: 10.1038/Nature09413  0.84
2010 Kadl A, Meher AK, Sharma PR, Lee MY, Doran AC, Johnstone SR, Elliott MR, Gruber F, Han J, Chen W, Kensler T, Ravichandran KS, Isakson BE, Wamhoff BR, Leitinger N. Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circulation Research. 107: 737-46. PMID 20651288 DOI: 10.1161/Circresaha.109.215715  0.84
2010 Johnstone SR, Best AK, Wright CS, Isakson BE, Errington RJ, Martin PE. Enhanced connexin 43 expression delays intra-mitotic duration and cell cycle traverse independently of gap junction channel function. Journal of Cellular Biochemistry. 110: 772-82. PMID 20512937 DOI: 10.1002/Jcb.22590  0.84
2010 Heberlein KR, Straub AC, Best AK, Greyson MA, Looft-Wilson RC, Sharma PR, Meher A, Leitinger N, Isakson BE. Plasminogen activator inhibitor-1 regulates myoendothelial junction formation. Circulation Research. 106: 1092-102. PMID 20133900 DOI: 10.1161/Circresaha.109.215723  0.84
2010 Straub AC, Johnstone SR, Heberlein KR, Rizzo MJ, Best AK, Boitano S, Isakson BE. Site-specific connexin phosphorylation is associated with reduced heterocellular communication between smooth muscle and endothelium. Journal of Vascular Research. 47: 277-86. PMID 20016202 DOI: 10.1159/000265562  0.84
2009 Johnstone S, Isakson B, Locke D. Biological and biophysical properties of vascular connexin channels. International Review of Cell and Molecular Biology. 278: 69-118. PMID 19815177 DOI: 10.1016/S1937-6448(09)78002-5  0.84
2009 Johnstone SR, Ross J, Rizzo MJ, Straub AC, Lampe PD, Leitinger N, Isakson BE. Oxidized phospholipid species promote in vivo differential cx43 phosphorylation and vascular smooth muscle cell proliferation. The American Journal of Pathology. 175: 916-24. PMID 19608875 DOI: 10.2353/Ajpath.2009.090160  0.84
2009 Heberlein KR, Straub AC, Isakson BE. The myoendothelial junction: breaking through the matrix? Microcirculation (New York, N.Y. : 1994). 16: 307-22. PMID 19330678 DOI: 10.1080/10739680902744404  0.48
2009 Brisset AC, Isakson BE, Kwak BR. Connexins in vascular physiology and pathology. Antioxidants & Redox Signaling. 11: 267-82. PMID 18834327 DOI: 10.1089/Ars.2008.2115  0.84
2008 Isakson BE, Best AK, Duling BR. Incidence of protein on actin bridges between endothelium and smooth muscle in arterioles demonstrates heterogeneous connexin expression and phosphorylation. American Journal of Physiology. Heart and Circulatory Physiology. 294: H2898-904. PMID 18408134 DOI: 10.1152/Ajpheart.91488.2007  0.48
2007 Isakson BE, Ramos SI, Duling BR. Ca2+ and inositol 1,4,5-trisphosphate-mediated signaling across the myoendothelial junction. Circulation Research. 100: 246-54. PMID 17218602 DOI: 10.1161/01.Res.0000257744.23795.93  0.44
2006 Figueroa XF, Isakson BE, Duling BR. Vascular gap junctions in hypertension. Hypertension. 48: 804-11. PMID 17015783 DOI: 10.1161/01.Hyp.0000242483.03361.Da  0.44
2006 Isakson BE, Olsen CE, Boitano S. Laminin-332 alters connexin profile, dye coupling and intercellular Ca2+ waves in ciliated tracheal epithelial cells. Respiratory Research. 7: 105. PMID 16884540 DOI: 10.1186/1465-9921-7-105  0.84
2006 Isakson BE, Kronke G, Kadl A, Leitinger N, Duling BR. Oxidized phospholipids alter vascular connexin expression, phosphorylation, and heterocellular communication. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2216-21. PMID 16857951 DOI: 10.1161/01.Atv.0000237608.19055.53  0.44
2006 Isakson BE, Damon DN, Day KH, Liao Y, Duling BR. Connexin40 and connexin43 in mouse aortic endothelium: evidence for coordinated regulation. American Journal of Physiology. Heart and Circulatory Physiology. 290: H1199-205. PMID 16284228 DOI: 10.1152/Ajpheart.00945.2005  0.84
2005 Olsen CO, Isakson BE, Seedorf GJ, Lubman RL, Boitano S. Extracellular matrix-driven alveolar epithelial cell differentiation in vitro. Experimental Lung Research. 31: 461-82. PMID 16047415 DOI: 10.1080/01902140590918830  0.84
2005 Isakson BE, Duling BR. Heterocellular contact at the myoendothelial junction influences gap junction organization. Circulation Research. 97: 44-51. PMID 15961721 DOI: 10.1161/01.Res.0000173461.36221.2E  0.44
2004 Figueroa XF, Isakson BE, Duling BR. Connexins: gaps in our knowledge of vascular function. Physiology (Bethesda, Md.). 19: 277-84. PMID 15381756 DOI: 10.1152/Physiol.00008.2004  0.44
2003 Isakson BE, Seedorf GJ, Lubman RL, Evans WH, Boitano S. Cell-cell communication in heterocellular cultures of alveolar epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 29: 552-61. PMID 12748060 DOI: 10.1165/Rcmb.2002-0281Oc  0.84
2002 Isakson BE, Seedorf GJ, Lubman RL, Boitano S. Heterocellular cultures of pulmonary alveolar epithelial cells grown on laminin-5 supplemented matrix. In Vitro Cellular & Developmental Biology. Animal. 38: 443-9. PMID 12605538 DOI: 10.1290/1071-2690(2002)038<0443:Hcopae>2.0.Co;2  0.84
2002 Boitano S, Isakson BE, Lubman RL. Culturing alveolar type I, alveolar type II, and mixed cell populations by altering the extracellular matrix promotes changes in intercellular signaling mechanisms. Chest. 121: 35S-36S. PMID 11893676 DOI: 10.1378/Chest.121.3_Suppl.35S-A  0.84
2001 Isakson BE, Lubman RL, Seedorf GJ, Boitano S. Modulation of pulmonary alveolar type II cell phenotype and communication by extracellular matrix and KGF American Journal of Physiology - Cell Physiology. 281. PMID 11546667 DOI: 10.1152/Ajpcell.2001.281.4.C1291  0.84
2001 Isakson BE, Evans WH, Boitano S. Intercellular Ca2+ signaling in alveolar epithelial cells through gap junctions and by extracellular ATP American Journal of Physiology - Lung Cellular and Molecular Physiology. 280. PMID 11159000 DOI: 10.1152/Ajplung.2001.280.2.L221  0.84
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