Owen McGuinness - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Endocrinology Biology, Cell Biology

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 McClatchey PM, Williams IM, Xu Z, Mignemi NA, Hughey CC, McGuinness OP, Beckman JA, Wasserman DH, Poole DC, Akerstrom T, Goldman D, Fraser GM, Ellis CG. Reply to Letter to the Editor: Perfusion controls muscle glucose uptake by altering the rate of glucose dispersion in vivo. American Journal of Physiology. Endocrinology and Metabolism. 318: E313-E317. PMID 32068464 DOI: 10.1152/ajpendo.00508.2019  0.36
2019 McClatchey PM, Williams IM, Xu Z, Mignemi NA, Hughey CC, McGuinness OP, Beckman JA, Wasserman DH. Perfusion Controls Muscle Glucose Uptake by Altering the Rate of Glucose Dispersion In Vivo. American Journal of Physiology. Endocrinology and Metabolism. PMID 31526289 DOI: 10.1152/ajpendo.00260.2019  0.36
2019 Mignemi NA, McClatchey PM, Kilchrist KV, Williams IM, Millis BA, Syring KE, Duvall CL, Wasserman DH, McGuinness OP. Rapid changes in the microvascular circulation of skeletal muscle impair insulin delivery during sepsis. American Journal of Physiology. Endocrinology and Metabolism. PMID 30860883 DOI: 10.1152/ajpendo.00501.2018  0.36
2018 McClatchey PM, Mignemi NA, Xu Z, Williams IM, Reusch JEB, McGuinness OP, Wasserman DH. Automated Quantification of Microvascular Perfusion. Microcirculation (New York, N.Y. : 1994). e12482. PMID 29908041 DOI: 10.1111/micc.12482  0.36
2015 Otero YF, Mulligan KX, Barnes TM, Ford EA, Malabanan CM, Zong H, Pessin JE, Wasserman DH, McGuinness OP. Enhanced Glucose Transport, but not Phosphorylation Capacity, Ameliorates Lipopolysaccharide-Induced Impairments in Insulin Stimulated-Muscle Glucose Uptake. Shock (Augusta, Ga.). PMID 26682946 DOI: 10.1097/SHK.0000000000000550  0.64
2015 Cyphert TJ, Morris RT, House LM, Barnes TM, Otero YF, Barham WJ, Hunt RP, Zaynagetdinov R, Yull FE, Blackwell TS, McGuinness OP. NF-κB-dependent airway inflammation triggers systemic insulin resistance. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 309: R1144-52. PMID 26377563 DOI: 10.1152/ajpregu.00442.2014  0.36
2015 Kolumam G, Chen MZ, Tong R, Zavala-Solorio J, Kates L, van Bruggen N, Ross J, Wyatt SK, Gandham VD, Carano RA, Dunshee DR, Wu AL, Haley B, Anderson K, Warming S, ... ... McGuinness OP, et al. Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex. Ebiomedicine. 2: 730-43. PMID 26288846 DOI: 10.1016/j.ebiom.2015.05.028  0.4
2015 House LM, Morris RT, Barnes TM, Lantier L, Cyphert TJ, McGuinness OP, Otero YF. Tissue inflammation and nitric oxide-mediated alterations in cardiovascular function are major determinants of endotoxin-induced insulin resistance. Cardiovascular Diabetology. 14: 56. PMID 25986700 DOI: 10.1186/s12933-015-0223-2  0.36
2015 Kolumam G, Chen MZ, Tong R, Zavala-Solorio J, Kates L, van Bruggen N, Ross J, Wyatt SK, Gandham VD, Carano RAD, Dunshee DR, Wu AL, Haley B, Anderson K, Warming S, ... ... McGuinness OP, et al. Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex Ebiomedicine. DOI: 10.1016/j.ebiom.2015.05.028  0.4
2014 Barnes TM, Otero YF, Elliott AD, Locke AD, Malabanan CM, Coldren AG, Brissova M, Piston DW, McGuinness OP. Interleukin-6 amplifies glucagon secretion: coordinated control via the brain and pancreas. American Journal of Physiology. Endocrinology and Metabolism. 307: E896-905. PMID 25205821 DOI: 10.1152/ajpendo.00343.2014  0.36
2014 Chen Z, Guo L, Zhang Y, Walzem RL, Pendergast JS, Printz RL, Morris LC, Matafonova E, Stien X, Kang L, Coulon D, McGuinness OP, Niswender KD, Davies SS. Incorporation of therapeutically modified bacteria into gut microbiota inhibits obesity. The Journal of Clinical Investigation. 124: 3391-406. PMID 24960158 DOI: 10.1172/JCI72517  0.4
2014 Otero YF, Stafford JM, McGuinness OP. Pathway-selective insulin resistance and metabolic disease: the importance of nutrient flux. The Journal of Biological Chemistry. 289: 20462-9. PMID 24907277 DOI: 10.1074/jbc.R114.576355  0.36
2014 Otero YF, Lundblad TM, Ford EA, House LM, McGuinness OP. Liver but not adipose tissue is responsive to the pattern of enteral feeding. Physiological Reports. 2: e00250. PMID 24744913 DOI: 10.1002/phy2.250  0.36
2014 Chen SS, Otero YF, Mulligan KX, Lundblad TM, Williams PE, McGuinness OP. Liver, but not muscle, has an entrainable metabolic memory. Plos One. 9: e86164. PMID 24465939 DOI: 10.1371/journal.pone.0086164  0.64
2013 Wei K, Piecewicz SM, McGinnis LM, Taniguchi CM, Wiegand SJ, Anderson K, Chan CW, Mulligan KX, Kuo D, Yuan J, Vallon M, Morton LC, Lefai E, Simon MC, Maher JJ, ... ... McGuinness OP, et al. A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition. Nature Medicine. 19: 1331-7. PMID 24037094 DOI: 10.1038/nm.3295  0.64
2013 Shi SQ, Ansari TS, McGuinness OP, Wasserman DH, Johnson CH. Circadian disruption leads to insulin resistance and obesity. Current Biology : Cb. 23: 372-81. PMID 23434278 DOI: 10.1016/j.cub.2013.01.048  0.36
2012 Drake KJ, Sidorov VY, McGuinness OP, Wasserman DH, Wikswo JP. Amino acids as metabolic substrates during cardiac ischemia. Experimental Biology and Medicine (Maywood, N.J.). 237: 1369-78. PMID 23354395 DOI: 10.1258/ebm.2012.012025  0.36
2012 Berglund ED, Li CY, Ayala JE, McGuinness OP, Wasserman DH. Regulation of Endogenous Glucose Production in Glucose Transporter 4 Over-Expressing Mice Plos One. 7. PMID 23285006 DOI: 10.1371/journal.pone.0052355  0.36
2012 Mulligan KX, Morris RT, Otero YF, Wasserman DH, McGuinness OP. Disassociation of muscle insulin signaling and insulin-stimulated glucose uptake during endotoxemia. Plos One. 7: e30160. PMID 22276152 DOI: 10.1371/journal.pone.0030160  0.64
2011 Ayala JE, Bracy DP, Malabanan C, James FD, Ansari T, Fueger PT, McGuinness OP, Wasserman DH. Hyperinsulinemic-euglycemic clamps in conscious, unrestrained mice. Journal of Visualized Experiments : Jove. PMID 22126863 DOI: 10.3791/3188  0.36
2011 Yin DP, Gao Q, Ma LL, Yan W, Williams PE, McGuinness OP, Wasserman DH, Abumrad NN. Assessment of different bariatric surgeries in the treatment of obesity and insulin resistance in mice. Annals of Surgery. 254: 73-82. PMID 21522012 DOI: 10.1097/SLA.0b013e3182197035  0.36
2011 Johnson PM, Chen SS, Santomango TS, Williams PE, Lacy DB, McGuinness OP. Continuous low-dose fructose infusion does not reverse glucagon-mediated decrease in hepatic glucose utilization. Metabolism: Clinical and Experimental. 60: 867-73. PMID 20940071 DOI: 10.1016/j.metabol.2010.08.006  0.4
2011 Tweedell A, Mulligan KX, Martel JE, Chueh FY, Santomango T, McGuinness OP. Metabolic response to endotoxin in vivo in the conscious mouse: role of interleukin-6. Metabolism: Clinical and Experimental. 60: 92-8. PMID 20102773 DOI: 10.1016/j.metabol.2009.12.022  0.64
2010 Ayala JE, Samuel VT, Morton GJ, Obici S, Croniger CM, Shulman GI, Wasserman DH, McGuinness OP. Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice. Disease Models & Mechanisms. 3: 525-34. PMID 20713647 DOI: 10.1242/dmm.006239  0.36
2010 Vaitheesvaran B, Chueh FY, Xu J, Trujillo C, Saad MF, Lee WN, McGuinness OP, Kurland IJ. Advantages of dynamic "closed loop" stable isotope flux phenotyping over static "open loop" clamps in detecting silent genetic and dietary phenotypes. Metabolomics : Official Journal of the Metabolomic Society. 6: 180-190. PMID 20445758 DOI: 10.1007/s11306-009-0190-2  0.64
2010 Shi S, Hida A, McGuinness OP, Wasserman DH, Yamazaki S, Johnson CH. Circadian clock gene Bmal1 is not essential; functional replacement with its paralog, Bmal2. Current Biology : Cb. 20: 316-21. PMID 20153195 DOI: 10.1016/j.cub.2009.12.034  0.36
2009 Wasserman DH, Ayala JE, McGuinness OP. Lost in translation. Diabetes. 58: 1947-50. PMID 19720822 DOI: 10.2337/db09-0537  0.36
2009 McGuinness OP, Ayala JE, Laughlin MR, Wasserman DH. NIH experiment in centralized mouse phenotyping: the Vanderbilt experience and recommendations for evaluating glucose homeostasis in the mouse. American Journal of Physiology. Endocrinology and Metabolism. 297: E849-55. PMID 19638507 DOI: 10.1152/ajpendo.90996.2008  0.36
2009 Lee-Young RS, Griffee SR, Lynes SE, Bracy DP, Ayala JE, McGuinness OP, Wasserman DH. Skeletal muscle AMP-activated protein kinase is essential for the metabolic response to exercise in vivo. The Journal of Biological Chemistry. 284: 23925-34. PMID 19525228 DOI: 10.1074/jbc.M109.021048  0.36
2009 Chen SS, Santomango TS, Williams PE, Lacy DB, McGuinness OP. Glucagon-mediated impairments in hepatic and peripheral tissue nutrient disposal are not aggravated by increased lipid availability. American Journal of Physiology. Endocrinology and Metabolism. 296: E1172-8. PMID 19208853 DOI: 10.1152/ajpendo.90821.2008  0.4
2007 Chen SS, Zhang Y, Santomango TS, Williams PE, Lacy DB, McGuinness OP. Glucagon chronically impairs hepatic and muscle glucose disposal. American Journal of Physiology. Endocrinology and Metabolism. 292: E928-35. PMID 17132827 DOI: 10.1152/ajpendo.00063.2006  0.4
2006 Chueh FY, Malabanan C, McGuinness OP. Impact of portal glucose delivery on glucose metabolism in conscious, unrestrained mice. American Journal of Physiology. Endocrinology and Metabolism. 291: E1206-11. PMID 16822956 DOI: 10.1152/ajpendo.00608.2005  0.64
2006 Ayala JE, Bracy DP, McGuinness OP, Wasserman DH. Considerations in the design of hyperinsulinemic-euglycemic clamps in the conscious mouse. Diabetes. 55: 390-7. PMID 16443772  0.36
2006 Nunemaker CS, Wasserman DH, McGuinness OP, Sweet IR, Teague JC, Satin LS. Insulin secretion in the conscious mouse is biphasic and pulsatile. American Journal of Physiology. Endocrinology and Metabolism. 290: E523-9. PMID 16249252 DOI: 10.1152/ajpendo.00392.2005  0.36
2005 Nunemaker CS, Zhang M, Wasserman DH, McGuinness OP, Powers AC, Bertram R, Sherman A, Satin LS. Individual mice can be distinguished by the period of their islet calcium oscillations: is there an intrinsic islet period that is imprinted in vivo? Diabetes. 54: 3517-22. PMID 16306370 DOI: 10.2337/diabetes.54.12.3517  0.36
2005 Chen SS, Torres-Sanchez CJ, Hosein N, Zhang Y, Lacy DB, Chang C, McGuinness OP. Route-dependent effect of nutritional support on liver glucose uptake. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 289: R1319-27. PMID 15994371 DOI: 10.1152/ajpregu.00175.2005  0.4
2005 Grubert JM, Lautz M, Lacy DB, Moore MC, Farmer B, Penaloza A, Cherrington AD, McGuinness OP. Impact of continuous and pulsatile insulin delivery on net hepatic glucose uptake. American Journal of Physiology. Endocrinology and Metabolism. 289: E232-40. PMID 15755768 DOI: 10.1152/ajpendo.00567.2004  0.4
2005 Fueger PT, Shearer J, Bracy DP, Posey KA, Pencek RR, McGuinness OP, Wasserman DH. Control of muscle glucose uptake: test of the rate-limiting step paradigm in conscious, unrestrained mice. The Journal of Physiology. 562: 925-35. PMID 15576451 DOI: 10.1113/jphysiol.2004.076158  0.36
2005 Chen SS, Torres-Sanchez CJ, Hosein N, Zhang Y, Lacy DB, McGuinness OP. Time course of the hepatic adaptation to TPN: interaction with glycogen depletion. American Journal of Physiology. Endocrinology and Metabolism. 288: E163-70. PMID 15339746 DOI: 10.1152/ajpendo.00192.2004  0.4
2004 Ma LJ, Mao SL, Taylor KL, Kanjanabuch T, Guan Y, Zhang Y, Brown NJ, Swift LL, McGuinness OP, Wasserman DH, Vaughan DE, Fogo AB. Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1. Diabetes. 53: 336-46. PMID 14747283  0.4
2004 Chen SS, Donmoyer CM, Pearson DA, Poole A, Zhang Y, Lacy DB, McGuinness OP. Impact of infection on glucose-dependent liver glucose uptake during TPN: interaction with insulin. American Journal of Physiology. Endocrinology and Metabolism. 286: E286-95. PMID 14532169 DOI: 10.1152/ajpendo.00286.2003  0.4
2003 Donmoyer CM, Chen SS, Lacy DB, Pearson DA, Poole A, Zhang Y, McGuinness OP. Infection impairs insulin-dependent hepatic glucose uptake during total parenteral nutrition. American Journal of Physiology. Endocrinology and Metabolism. 284: E574-82. PMID 12441309 DOI: 10.1152/ajpendo.00035.2002  0.4
2002 Donmoyer CM, Lacy DB, Zhang Y, Chen SS, McGuinness OP. Impact of chronic fructose infusion on hepatic metabolism during TPN administration. American Journal of Physiology. Endocrinology and Metabolism. 283: E1151-8. PMID 12424103 DOI: 10.1152/ajpendo.00223.2001  0.4
2002 Chen SS, Donmoyer CM, Ejiofor J, McCay J, Archuletta R, Lacy DB, McGuinness OP. Impact of intraportal N(omega)-nitro-L-arginine infusion on hepatic glucose metabolism in total parenteral nutrition-adapted dogs: interaction with infection. Metabolism: Clinical and Experimental. 51: 274-83. PMID 11887160 DOI: 10.1053/meta.2002.30501  0.4
2001 Donmoyer CM, Ejiofor J, Lacy DB, Chen SS, McGuinness OP. Fructose augments infection-impaired net hepatic glucose uptake during TPN administration. American Journal of Physiology. Endocrinology and Metabolism. 280: E703-11. PMID 11287352  0.4
2000 Chen SS, Donmoyer C, Zhang Y, Hande SA, Lacy DB, McGuinness OP. Impact of enteral and parenteral nutrition on hepatic and muscle glucose metabolism. Jpen. Journal of Parenteral and Enteral Nutrition. 24: 255-60. PMID 11011779 DOI: 10.1177/0148607100024005255  0.4
2000 Donmoyer CM, Chen SS, Hande SA, Lacy DB, Ejiofor J, McGuinness OP. Hyperinsulinemia compensates for infection-induced impairment in net hepatic glucose uptake during TPN. American Journal of Physiology. Endocrinology and Metabolism. 279: E235-43. PMID 10913021  0.4
2000 McGuinness OP, Ejiofor J, Lacy DB, Schrom N. Hepatic glucose metabolism during intraduodenal glucose infusion: impact of infection. American Journal of Physiology. Endocrinology and Metabolism. 279: E108-15. PMID 10893329 DOI: 10.1152/AJPENDO.2000.279.1.E108  0.4
1998 Lang CH, Frost RA, Ejiofor J, Lacy DB, McGuinness OP. Hepatic production and intestinal uptake of IGF-I: response to infection. American Journal of Physiology. Gastrointestinal and Liver Physiology. 275: G1291-G1298. PMID 29585795 DOI: 10.1152/ajpgi.1998.275.6.G1291  0.4
1998 McGuinness OP, Donmoyer C, Ejiofor J, McElligott S, Lacy DB. Hepatic and muscle glucose metabolism during total parenteral nutrition: impact of infection. American Journal of Physiology. Endocrinology and Metabolism. 275: E763-E769. PMID 29585223 DOI: 10.1152/ajpendo.1998.275.5.E763  0.4
1998 Meinz H, Lacy DB, Ejiofor J, McGuinness OP. Alterations in hepatic gluconeogenic amino acid uptake and gluconeogenesis in the endotoxin treated conscious dog. Shock (Augusta, Ga.). 9: 296-303. PMID 9565259 DOI: 10.1097/00024382-199804000-00010  0.4
1996 McGuinness OP, Lacy DB, Ejiofor J, Bagby GG. Hepatic release of tumor necrosis factor in the endotoxin-treated conscious dog. Shock (Augusta, Ga.). 5: 344-8. PMID 9156790 DOI: 10.1097/00024382-199605000-00006  0.4
1996 McGuinness OP, Lacy DB, Eliasson K. Hyperglucagonemia and hepatic glucose metabolism during infection in the conscious dog. The American Journal of Physiology. 270: E580-8. PMID 8928762 DOI: 10.1152/ajpendo.1996.270.4.E580  0.4
1995 McGuinness OP, Lacy DB, Anderson J. Effect of acute glucagon removal on metabolic response to infection in conscious dog. The American Journal of Physiology. 268: E92-9. PMID 7840188 DOI: 10.1152/ajpendo.1995.268.1.E92  0.4
1993 Goldstein RE, Wasserman DH, McGuinness OP, Lacy DB, Cherrington AD, Abumrad NN. Effects of chronic elevation in plasma cortisol on hepatic carbohydrate metabolism. The American Journal of Physiology. 264: E119-27. PMID 8430780 DOI: 10.1152/ajpendo.1993.264.1.E119  0.4
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