Year |
Citation |
Score |
2023 |
Shields MA, Metropulos AE, Spaulding C, Hirose T, Ohno S, Pham TND, Munshi HG. BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss. Biorxiv : the Preprint Server For Biology. PMID 37745543 DOI: 10.1101/2023.09.14.557654 |
0.655 |
|
2022 |
Pham TN, Spaulding C, Shields MA, Metropulos AE, Shah DN, Khalafalla MG, Principe DR, Bentrem DJ, Munshi HG. Inhibition of MNKs promotes macrophage immunosuppressive phenotype to limit CD8+ T cell antitumor immunity. Jci Insight. 7. PMID 35380995 DOI: 10.1172/jci.insight.152731 |
0.667 |
|
2022 |
Shields MA, Spaulding C, Metropulos AE, Khalafalla MG, Pham TND, Munshi HG. Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin. Cell Reports. 38: 110441. PMID 35235808 DOI: 10.1016/j.celrep.2022.110441 |
0.68 |
|
2022 |
Principe DR, Underwood PW, Kumar S, Timbers KE, Koch RM, Trevino JG, Munshi HG, Rana A. Loss of SMAD4 Is Associated With Poor Tumor Immunogenicity and Reduced PD-L1 Expression in Pancreatic Cancer. Frontiers in Oncology. 12: 806963. PMID 35155243 DOI: 10.3389/fonc.2022.806963 |
0.323 |
|
2022 |
Principe DR, Xiong R, Li Y, Pham TND, Kamath SD, Dubrovskyi O, Ratia K, Huang F, Zhao J, Shen Z, Thummuri D, Daohong Z, Underwood PW, Trevino J, Munshi HG, et al. XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35064087 DOI: 10.1073/pnas.2116764119 |
0.331 |
|
2021 |
Kwong AJ, Pham TND, Oelschlager HE, Munshi HG, Scheidt KA. Rational Design, Optimization, and Biological Evaluation of Novel MEK4 Inhibitors against Pancreatic Adenocarcinoma. Acs Medicinal Chemistry Letters. 12: 1559-1567. PMID 34676038 DOI: 10.1021/acsmedchemlett.1c00376 |
0.334 |
|
2021 |
Pham TND, Shields MA, Spaulding C, Principe DR, Li B, Underwood PW, Trevino JG, Bentrem DJ, Munshi HG. Preclinical Models of Pancreatic Ductal Adenocarcinoma and Their Utility in Immunotherapy Studies. Cancers. 13. PMID 33503832 DOI: 10.3390/cancers13030440 |
0.653 |
|
2020 |
Pham TND, Spaulding C, Munshi HG. Controlling TIME: How MNK Kinases Function to Shape Tumor Immunity. Cancers. 12. PMID 32731503 DOI: 10.3390/Cancers12082096 |
0.367 |
|
2020 |
Principe DR, Kamath SD, Munshi HG, Mohindra NA. Metastatic Thymoma Harboring a Deleterious BRCA2 Mutation Derives Durable Clinical Benefit from Olaparib. The Oncologist. 25: 301-305. PMID 32297440 DOI: 10.1634/Theoncologist.2019-0393 |
0.321 |
|
2020 |
Principe DR, Narbutis M, Kumar S, Park A, Viswakarma N, Dorman MJ, Kamath SD, Grippo PJ, Fishel ML, Hwang RF, Thummuri D, Underwood PW, Munshi HG, Trevino JG, Rana A. Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination Immunotherapy. Cancer Research. PMID 32238357 DOI: 10.1158/0008-5472.Can-19-2959 |
0.451 |
|
2019 |
Pham TND, Stempel S, Shields MA, Spaulding C, Kumar K, Bentrem DJ, Matsangou M, Munshi HG. Quercetin Enhances the Anti-Tumor Effects of BET Inhibitors by Suppressing hnRNPA1. International Journal of Molecular Sciences. 20. PMID 31480735 DOI: 10.3390/Ijms20174293 |
0.711 |
|
2019 |
Torres C, Mancinelli G, Cordoba-Chacon J, Viswakarma N, Castellanos K, Grimaldo S, Kumar S, Principe D, Dorman MJ, McKinney R, Hirsch E, Dawson D, Munshi HG, Rana A, Grippo PJ. p110γ deficiency protects against pancreatic carcinogenesis yet predisposes to diet-induced hepatotoxicity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31266893 DOI: 10.1073/Pnas.1813012116 |
0.393 |
|
2019 |
Eckerdt F, Bell JB, Beauchamp EM, Clymer J, Blyth GT, Kosciuczuk EM, Ma Q, Chen DZ, Horbinski C, Goldman S, Munshi HG, Hashizume R, Platanias LC. Potent Antineoplastic Effects of Combined PI3Kα-MNK Inhibition in Medulloblastoma. Molecular Cancer Research : McR. PMID 30842251 DOI: 10.1158/1541-7786.Mcr-18-1193 |
0.439 |
|
2019 |
Ebine K, Chow CR, Munshi HG. Quantitative Method to Track Proteolytic Invasion in 3D Collagen. Methods in Molecular Biology (Clifton, N.J.). 1882: 161-169. PMID 30378053 DOI: 10.1007/978-1-4939-8879-2_15 |
0.447 |
|
2019 |
Pham T, Stempel S, Shields M, Spaulding C, Kumar K, Bentrem D, Munshi H. Abstract 2086: Targeting the MNK effector hnRNPA1 enhances the efficacy of BET inhibitors in cancer cells Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2086 |
0.694 |
|
2019 |
Principe DR, Narbutis M, Kumar S, Park A, Viswakarma N, Dorman MJ, Kamath SD, Munshi HG, Rana A. Abstract A20: Gemcitabine primes the pancreatic tumor microenvironment for second-line immunotherapy Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A20 |
0.464 |
|
2018 |
Principe DR, Park A, Dorman MJ, Kumar S, Viswakarma N, Rubin J, Torres C, McKinney R, Munshi HG, Grippo PJ, Rana A. TGFβ Blockade Augments PD-1 Inhibition to Promote T-Cell Mediated Regression of Pancreatic Cancer. Molecular Cancer Therapeutics. PMID 30587556 DOI: 10.1158/1535-7163.Mct-18-0850 |
0.43 |
|
2018 |
Pham TN, Kumar K, DeCant BT, Shang M, Munshi SZ, Matsangou M, Ebine K, Munshi HG. Induction of MNK kinases-dependent eIF4E phosphorylation by inhibitors targeting BET proteins limits efficacy of BET inhibitors. Molecular Cancer Therapeutics. PMID 30446586 DOI: 10.1158/1535-7163.Mct-18-0768 |
0.413 |
|
2018 |
Ebine K, Kumar K, Pham TN, Shields MA, Collier KA, Shang M, DeCant BT, Urrutia R, Hwang RF, Grimaldo S, Principe DR, Grippo PJ, Bentrem DJ, Munshi HG. Interplay between interferon regulatory factor 1 and BRD4 in the regulation of PD-L1 in pancreatic stellate cells. Scientific Reports. 8: 13225. PMID 30185888 DOI: 10.1038/S41598-018-31658-1 |
0.669 |
|
2018 |
Principe DR, Overgaard NH, Park AJ, Diaz AM, Torres C, McKinney R, Dorman MJ, Castellanos K, Schwind R, Dawson DW, Rana A, Maker A, Munshi HG, Rund LA, Grippo PJ, et al. KRAS and TP53 Cooperate to Induce Pancreatic Ductal Adenocarcinoma in Sus scrofa Pigs. Scientific Reports. 8: 12548. PMID 30135483 DOI: 10.1038/S41598-018-30916-6 |
0.426 |
|
2018 |
Fischietti M, Arslan AD, Sassano A, Saleiro D, Majchrzak-Kita B, Ebine K, Munshi HG, Fish EN, Platanias LC. Slfn2 Regulates Type I Interferon Responses by Modulating the NFĸB Pathway. Molecular and Cellular Biology. PMID 29866656 DOI: 10.1128/Mcb.00053-18 |
0.319 |
|
2018 |
Kumar K, Ebine K, Pham T, Shang M, Munshi HG. Abstract 4500: BET proteins regulate hyaluronan synthases in pancreatic ductal adenocarcinoma Cancer Research. 78: 4500-4500. DOI: 10.1158/1538-7445.Am2018-4500 |
0.475 |
|
2018 |
Pham T, Decant BT, Kumar K, Shang M, Matsangou M, Ebine K, Munshi HG. Abstract 2989: BET inhibitors induce Rac1-dependent MNK and eIF4E phosphorylation in cancer cells Cancer Research. 78: 2989-2989. DOI: 10.1158/1538-7445.Am2018-2989 |
0.465 |
|
2017 |
Principe DR, Diaz AM, Torres C, Mangan RJ, DeCant B, McKinney R, Tsao MS, Lowy A, Munshi HG, Jung B, Grippo PJ. TGFβ engages MEK/ERK to differentially regulate benign and malignant pancreas cell function. Oncogene. PMID 28368414 DOI: 10.1038/Onc.2016.500 |
0.473 |
|
2017 |
Kumar K, DeCant BT, Grippo PJ, Hwang RF, Bentrem DJ, Ebine K, Munshi HG. BET inhibitors block pancreatic stellate cell collagen I production and attenuate fibrosis in vivo. Jci Insight. 2: e88032. PMID 28194432 DOI: 10.1172/Jci.Insight.88032 |
0.551 |
|
2017 |
Ebine K, DeCant BT, Collier KA, Pham TN, Kumar K, Munshi HG. Abstract 1679: BET inhibitors suppress PD-L1 expression in pancreatic stellate cells Cancer Research. 77: 1679-1679. DOI: 10.1158/1538-7445.Am2017-1679 |
0.458 |
|
2016 |
Abedin SM, Boddy CS, Munshi HG. BET inhibitors in the treatment of hematologic malignancies: current insights and future prospects. Oncotargets and Therapy. 9: 5943-5953. PMID 27729803 DOI: 10.2147/Ott.S100515 |
0.373 |
|
2016 |
Ebine K, Chow CR, DeCant BT, Hattaway HZ, Grippo PJ, Kumar K, Munshi HG. Slug inhibits pancreatic cancer initiation by blocking Kras-induced acinar-ductal metaplasia. Scientific Reports. 6: 29133. PMID 27364947 DOI: 10.1038/Srep29133 |
0.501 |
|
2016 |
Wang X, Chow CR, Ebine K, Lee J, Rosner MR, Pan T, Munshi HG. Interaction of tRNA with MEK2 in pancreatic cancer cells. Scientific Reports. 6: 28260. PMID 27301426 DOI: 10.1038/Srep28260 |
0.399 |
|
2016 |
Sahai V, Redig AJ, Collier KA, Eckerdt FD, Munshi HG. Targeting bet bromodomain proteins in solid tumors. Oncotarget. PMID 27283767 DOI: 10.18632/Oncotarget.9804 |
0.386 |
|
2016 |
Principe DR, DeCant B, Staudacher J, Vitello D, Mangan RJ, Wayne EA, Mascariñas E, Diaz AM, Bauer J, McKinney RD, Khazaie K, Pasche B, Dawson DW, Munshi HG, Grippo PJ, et al. Loss of TGFβ signaling promotes colon cancer progression and tumor-associated inflammation. Oncotarget. PMID 27270652 DOI: 10.18632/Oncotarget.9830 |
0.431 |
|
2016 |
Principe DR, DeCant B, Diaz AM, Mangan RJ, Hwang R, Lowy A, Shetuni BB, Sreekumar BK, Chung C, Bentrem DJ, Munshi HG, Jung B, Grippo PJ, Bishehsari F. PEDF inhibits pancreatic tumorigenesis by attenuating the fibroinflammatory reaction. Oncotarget. PMID 27058416 DOI: 10.18632/Oncotarget.8587 |
0.514 |
|
2016 |
Principe DR, DeCant B, Mascarinas E, Wayne E, Diaz A, Akagi N, Hwang RF, Pasche B, Dawson DW, Fang D, Bentrem DJ, Munshi HG, Jung B, Grippo PJ. TGFβ signaling in the pancreatic tumor microenvironment promotes fibrosis and immune evasion to facilitate tumorigenesis. Cancer Research. PMID 26980767 DOI: 10.1158/0008-5472.Can-15-1293 |
0.511 |
|
2016 |
Kumar K, DeCant B, Hattaway HZ, Grippo PJ, Bentrem DJ, Ebine K, Munshi HG. Abstract B17: BET inhibitors block pancreatic stellate cell collagen production and attenuate fibrosis in vivo Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-B17 |
0.521 |
|
2015 |
Kumar K, Chow CR, Ebine K, Arslan AD, Kwok B, Bentrem DJ, Eckerdt FD, Platanias LC, Munshi HG. Differential Regulation of ZEB1 and EMT by MAPK-interacting protein kinases (MNKs) and eIF4E in Pancreatic Cancer. Molecular Cancer Research : McR. PMID 26609108 DOI: 10.1158/1541-7786.Mcr-15-0285 |
0.413 |
|
2015 |
Chow CR, Ebine K, Knab LM, Bentrem DJ, Kumar K, Munshi HG. Cancer Cell Invasion in 3D collagen is Differentially Regulated by Gα13 and Discoidin Domain Receptor 1-Par3 Signaling. The Journal of Biological Chemistry. PMID 26589794 DOI: 10.1074/Jbc.M115.669606 |
0.467 |
|
2015 |
Sassano A, Mavrommatis E, Arslan AD, Kroczynska B, Beauchamp EM, Khuon S, Chew TL, Green KJ, Munshi HG, Verma AK, Platanias LC. Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells. Molecular and Cellular Biology. 35: 2684-98. PMID 26012550 DOI: 10.1128/Mcb.00019-15 |
0.448 |
|
2015 |
Kumar K, Raza SS, Knab LM, Chow CR, Kwok B, Bentrem DJ, Popovic R, Ebine K, Licht JD, Munshi HG. GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1. Scientific Reports. 5: 9489. PMID 25807524 DOI: 10.1038/Srep09489 |
0.423 |
|
2015 |
Gounaris E, Heiferman MJ, Heiferman JR, Shrivastav M, Vitello D, Blatner NR, Knab LM, Phillips JD, Cheon EC, Grippo PJ, Khazaie K, Munshi HG, Bentrem DJ. Zileuton, 5-lipoxygenase inhibitor, acts as a chemopreventive agent in intestinal polyposis, by modulating polyp and systemic inflammation. Plos One. 10: e0121402. PMID 25747113 DOI: 10.1371/Journal.Pone.0121402 |
0.371 |
|
2015 |
Knab LM, Belotte J, Munshi HG, Bentrem DJ. Comparative effectiveness in esophagogastric cancer. Cancer Treatment and Research. 164: 121-42. PMID 25677022 DOI: 10.1007/978-3-319-12553-4_8 |
0.32 |
|
2015 |
Knab LM, Schultz M, Principe DR, Mascarinas WE, Gounaris E, Munshi HG, Grippo PJ, Bentrem DJ. Ablation of 5-lipoxygenase mitigates pancreatic lesion development. The Journal of Surgical Research. 194: 481-7. PMID 25454978 DOI: 10.1016/J.Jss.2014.10.021 |
0.368 |
|
2015 |
DeCant B, Principe D, Wayne E, Mascarinas E, Munshi H, Jung B, Grippo P. Abstract A21: Stromal-derived TGFβ facilitates pancreatic cancer development via repression of T-cell mediated cytotoxicity Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A21 |
0.539 |
|
2015 |
Principe DR, DeCant B, Mangan RJ, Wayne EA, Diaz AM, Vitello D, Munshi HG, Grippo P, Jung B. Abstract 2361: TGFβ signaling deficiency enhances tumor associated inflammation in colon cancer Cancer Research. 75: 2361-2361. DOI: 10.1158/1538-7445.Am2015-2361 |
0.395 |
|
2015 |
Principe DR, DeCant B, Diaz AM, Mangan RJ, Wayne EA, Bentrem DJ, Munshi HG, Jung BH, Grippo P, Bishehsari F. 131 PEDF Opposes Pancreatic Tumorigenesis by Affecting Tumor-Associated Inflammation and Fibrosis Gastroenterology. 148: S-34. DOI: 10.1016/S0016-5085(15)30120-7 |
0.385 |
|
2014 |
Knab LM, Ebine K, Chow CR, Raza SS, Sahai V, Patel AP, Kumar K, Bentrem DJ, Grippo PJ, Munshi HG. Snail cooperates with Kras G12D in vivo to increase stem cell factor and enhance mast cell infiltration. Molecular Cancer Research : McR. 12: 1440-8. PMID 24944064 DOI: 10.1158/1541-7786.Mcr-14-0111 |
0.476 |
|
2014 |
Sahai V, Kumar K, Knab LM, Chow CR, Raza SS, Bentrem DJ, Ebine K, Munshi HG. BET bromodomain inhibitors block growth of pancreatic cancer cells in three-dimensional collagen. Molecular Cancer Therapeutics. 13: 1907-17. PMID 24807963 DOI: 10.1158/1535-7163.Mct-13-0925 |
0.476 |
|
2014 |
Principe DR, Doll JA, Bauer J, Jung B, Munshi HG, Bartholin L, Pasche B, Lee C, Grippo PJ. TGF-β: duality of function between tumor prevention and carcinogenesis. Journal of the National Cancer Institute. 106: djt369. PMID 24511106 DOI: 10.1093/Jnci/Djt369 |
0.35 |
|
2014 |
Raza SS, Knab M, Chow C, Kumar K, Ebine K, Munshi HG. Development of resistance to BET bromodomain inhibitor JQ1 and demonstration of epithelial-mesenchymal transition in pancreatic cancer cells. Journal of Clinical Oncology. 32: e15263-e15263. DOI: 10.1200/Jco.2014.32.15_Suppl.E15263 |
0.384 |
|
2013 |
Shields MA, Ebine K, Sahai V, Kumar K, Siddiqui K, Hwang RF, Grippo PJ, Munshi HG. Snail cooperates with KrasG12D to promote pancreatic fibrosis. Molecular Cancer Research : McR. 11: 1078-87. PMID 23761168 DOI: 10.1158/1541-7786.Mcr-12-0637 |
0.754 |
|
2013 |
Dangi-Garimella S, Sahai V, Ebine K, Kumar K, Munshi HG. Three-dimensional collagen I promotes gemcitabine resistance in vitro in pancreatic cancer cells through HMGA2-dependent histone acetyltransferase expression. Plos One. 8: e64566. PMID 23696899 DOI: 10.1371/Journal.Pone.0064566 |
0.458 |
|
2013 |
Sahai V, Dangi-Garimella S, Ebine K, Kumar K, Munshi HG. Promotion of gemcitabine resistance in pancreatic cancer cells by three-dimensional collagen I through HMGA2-dependent histone acetyltransferase expression. Journal of Clinical Oncology. 31: 172-172. DOI: 10.1200/Jco.2013.31.4_Suppl.172 |
0.484 |
|
2013 |
Sahai V, Kumar K, Ebine K, Nimeiri H, Munshi HG. Abstract 2449: The bromodomain inhibitor JQ1 blocks growth of pancreatic cancer cells in 3D collagen. Cancer Research. 73: 2449-2449. DOI: 10.1158/1538-7445.Am2013-2449 |
0.448 |
|
2013 |
Kumar K, Sahai V, Ebine K, Munshi HG. Abstract 1517: Pancreatic stellate cells and chemoresistant pancreatic cancer cells induce EMT gene expression in normal pancreatic ductal cells. Cancer Research. 73: 1517-1517. DOI: 10.1158/1538-7445.Am2013-1517 |
0.481 |
|
2013 |
Knab LM, Ebine K, Grippo P, Bentrem DJ, Munshi H. Snail cooperates with mutant Kras to promote pancreatic inflammatory cell infiltration Journal of the American College of Surgeons. 217: S132-S133. DOI: 10.1016/J.Jamcollsurg.2013.07.308 |
0.377 |
|
2012 |
Grippo PJ, Fitchev PS, Bentrem DJ, Melstrom LG, Dangi-Garimella S, Krantz SB, Heiferman MJ, Chung C, Adrian K, Cornwell ML, Flesche JB, Rao SM, Talamonti MS, Munshi HG, Crawford SE. Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice. Gut. 61: 1454-64. PMID 22234980 DOI: 10.1136/Gutjnl-2011-300821 |
0.418 |
|
2012 |
Shields MA, Krantz SB, Bentrem DJ, Dangi-Garimella S, Munshi HG. Interplay between β1-integrin and Rho signaling regulates differential scattering and motility of pancreatic cancer cells by snail and Slug proteins. The Journal of Biological Chemistry. 287: 6218-29. PMID 22232555 DOI: 10.1074/Jbc.M111.308940 |
0.753 |
|
2012 |
Shields MA, Dangi-Garimella S, Redig AJ, Munshi HG. Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression. The Biochemical Journal. 441: 541-52. PMID 22187935 DOI: 10.1042/Bj20111240 |
0.738 |
|
2012 |
Krantz SB, Shields MA, Dangi-Garimella S, Munshi HG, Bentrem DJ. Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression. The Journal of Surgical Research. 173: 105-12. PMID 22099597 DOI: 10.1016/J.Jss.2011.09.020 |
0.719 |
|
2012 |
Dangi-Garimella S, Sahai V, Shields MA, Munshi HG. Effect of three-dimensional collagen I and global histone acetylation on gemcitabine resistance in pancreatic cancer cells. Journal of Clinical Oncology. 30: e14515-e14515. DOI: 10.1200/Jco.2012.30.15_Suppl.E14515 |
0.738 |
|
2012 |
Dangi-Garimella SY, Munshi HG. Abstract 3106: Collagen-mediated chromatin remodeling promotes chemoresistance in pancreatic cancer Cancer Research. 72: 3106-3106. DOI: 10.1158/1538-7445.Am2012-3106 |
0.492 |
|
2012 |
Shields MA, Khan MW, Grippo PJ, Munshi HG. Abstract 1336: Concurrent Snail expression and Kras mutation promote pancreatic fibrosis Cancer Research. 72: 1336-1336. DOI: 10.1158/1538-7445.Am2012-1336 |
0.726 |
|
2011 |
Kircher SM, Krantz SB, Nimeiri HS, Mulcahy MF, Munshi HG, Benson AB. Therapy of locally advanced pancreatic adenocarcinoma: Unresectable and borderline patients Expert Review of Anticancer Therapy. 11: 1555-1565. PMID 21999129 DOI: 10.1586/Era.11.125 |
0.335 |
|
2011 |
Krantz SB, Shields MA, Dangi-Garimella S, Cheon EC, Barron MR, Hwang RF, Rao MS, Grippo PJ, Bentrem DJ, Munshi HG. MT1-MMP cooperates with Kras(G12D) to promote pancreatic fibrosis through increased TGF-β signaling. Molecular Cancer Research : McR. 9: 1294-304. PMID 21856775 DOI: 10.1158/1541-7786.Mcr-11-0023 |
0.75 |
|
2011 |
Ward ST, Dangi-Garimella S, Shields MA, Collander BA, Siddiqui MA, Krantz SB, Munshi HG. Ethanol differentially regulates snail family of transcription factors and invasion of premalignant and malignant pancreatic ductal cells. Journal of Cellular Biochemistry. 112: 2966-73. PMID 21678462 DOI: 10.1002/Jcb.23215 |
0.723 |
|
2011 |
Shields MA, Dangi-Garimella S, Krantz SB, Bentrem DJ, Munshi HG. Pancreatic cancer cells respond to type I collagen by inducing snail expression to promote membrane type 1 matrix metalloproteinase-dependent collagen invasion Journal of Biological Chemistry. 286: 10495-10504. PMID 21288898 DOI: 10.1074/Jbc.M110.195628 |
0.765 |
|
2011 |
Cheon EC, Khazaie K, Khan MW, Strouch MJ, Krantz SB, Phillips J, Blatner NR, Hix LM, Zhang M, Dennis KL, Salabat MR, Heiferman M, Grippo PJ, Munshi HG, Gounaris E, et al. Mast cell 5-lipoxygenase activity promotes intestinal polyposis in APCDelta468 mice. Cancer Research. 71: 1627-36. PMID 21216893 DOI: 10.1158/0008-5472.Can-10-1923 |
0.458 |
|
2011 |
Dangi-Garimella S, Krantz SB, Barron MR, Shields MA, Heiferman MJ, Grippo PJ, Bentrem DJ, Munshi HG. Three-dimensional collagen I promotes gemcitabine resistance in pancreatic cancer through MT1-MMP-mediated expression of HMGA2. Cancer Research. 71: 1019-28. PMID 21148071 DOI: 10.1158/0008-5472.Can-10-1855 |
0.755 |
|
2011 |
Munshi HG, Stack MS. Understanding epithelial-mesenchymal transition may reveal novel therapeutic targets for Oral squamous cell carcinoma Current Cancer Therapy Reviews. 7: 104-110. DOI: 10.2174/1573394711107020104 |
0.325 |
|
2011 |
Danqi-Garimella SY, Munshi HG. Abstract C52: Collagen-mediated chromatin remodeling promotes chemoresistance in pancreatic cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-C52 |
0.497 |
|
2011 |
Krantz SB, Shields MS, Dangi-Garimella S, Cheon EC, Barron MR, Hwang RF, Rao MS, Grippo PJ, Bentrem DJ, Munshi HG. Abstract 515: Membrane type 1-matrix metalloproteinase cooperates with KrasG12D to promote pancreatic fibrosis through transforming growth factor-β activation of pancreatic stellate cells Cancer Research. 71: 515-515. DOI: 10.1158/1538-7445.Am2011-515 |
0.548 |
|
2010 |
Krantz SB, Shields MA, Dangi-Garimella S, Bentrem DJ, Munshi HG. Contribution of epithelial-mesenchymal transition to pancreatic cancer progression. Cancers. 2: 2084-97. PMID 24281219 DOI: 10.3390/Cancers2042084 |
0.732 |
|
2010 |
Dangi-Garimella S, Strouch MJ, Grippo PJ, Bentrem DJ, Munshi HG. Collagen regulation of let-7 in pancreatic cancer involves TGF-β1-mediated membrane type 1-matrix metalloproteinase expression. Oncogene. 30: 1002-8. PMID 21057545 DOI: 10.1038/Onc.2010.485 |
0.544 |
|
2010 |
Katsoulidis E, Mavrommatis E, Woodard J, Shields MA, Sassano A, Carayol N, Sawicki KT, Munshi HG, Platanias LC. Role of interferon {alpha} (IFN{alpha})-inducible Schlafen-5 in regulation of anchorage-independent growth and invasion of malignant melanoma cells. The Journal of Biological Chemistry. 285: 40333-41. PMID 20956525 DOI: 10.1074/Jbc.M110.151076 |
0.706 |
|
2010 |
Dangi-Garimella S, Redig AJ, Shields MA, Siddiqui MA, Munshi HG. Rho-ROCK-myosin signaling mediates membrane type 1 matrix metalloproteinase-induced cellular aggregation of keratinocytes. The Journal of Biological Chemistry. 285: 28363-72. PMID 20605790 DOI: 10.1074/Jbc.M110.146019 |
0.728 |
|
2010 |
Strouch MJ, Cheon EC, Salabat MR, Krantz SB, Gounaris E, Melstrom LG, Dangi-Garimella S, Wang E, Munshi HG, Khazaie K, Bentrem DJ. Crosstalk between mast cells and pancreatic cancer cells contributes to pancreatic tumor progression Clinical Cancer Research. 16: 2257-2265. PMID 20371681 DOI: 10.1158/1078-0432.Ccr-09-1230 |
0.521 |
|
2010 |
Redig AJ, Munshi HG. Care of the cancer survivor: metabolic syndrome after hormone-modifying therapy. The American Journal of Medicine. 123: 87.e1-6. PMID 20102997 DOI: 10.1016/J.Amjmed.2009.06.022 |
0.309 |
|
2010 |
Krantz SB, Shields MA, Dangi-Garimella S, Bentrem DJ, Munshi HG. Contribution of epithelial-mesenchymal transition to pancreatic cancer progression Cancers. 2: 2084-2097. DOI: 10.3390/cancers2042084 |
0.715 |
|
2010 |
Krantz SB, Dangi-Garimella S, Shields MA, Grippo PJ, Bentrem DJ, Munshi HG. Role of MT1-MMP and Kras in invasive pancreatic tumors with pronounced fibrosis. Journal of Clinical Oncology. 28: 4158-4158. DOI: 10.1200/Jco.2010.28.15_Suppl.4158 |
0.734 |
|
2010 |
Shields MA, Dangi-Garimella S, Krantz S, Bentrem DJ, Munshi HG. Abstract 4812: Collagen regulation of Snail expression in pancreatic cancer involves TGF-β1 signaling Cancer Research. 70: 4812-4812. DOI: 10.1158/1538-7445.Am10-4812 |
0.771 |
|
2010 |
Dangi-Garimella SY, Munshi HG. Abstract 3933: Collagen-proteinase cross-talk promotes gemcitabine resistance in pancreatic cancer Cancer Research. 70: 3933-3933. DOI: 10.1158/1538-7445.Am10-3933 |
0.521 |
|
2010 |
Krantz S, Strouch M, Cheon E, Heiferman M, Munshi H, Khazaie K, Bentrem D. Mast Cells Can Mediate Increased Invasion and Pancreatic Cancer Cell Lines Journal of Surgical Research. 158: 192-193. DOI: 10.1016/J.Jss.2009.11.072 |
0.472 |
|
2010 |
Krantz SB, Dangi-Garimella S, Shields MA, Grippo PJ, Bentrem DJ, Munshi HG. MT1-MMP cooperates with kras to generate intraductal papillary mucinous neoplasms with pronounced fibrosis Journal of the American College of Surgeons. 211: S121-S122. DOI: 10.1016/J.Jamcollsurg.2010.06.323 |
0.688 |
|
2009 |
Moss NM, Barbolina MV, Liu Y, Sun L, Munshi HG, Stack MS. Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: a potential role in I.p. metastatic dissemination. Cancer Research. 69: 7121-9. PMID 19706774 DOI: 10.1158/0008-5472.Can-08-4151 |
0.506 |
|
2009 |
Joseph MJ, Dangi-Garimella S, Shields MA, Diamond ME, Sun L, Koblinski JE, Munshi HG. Slug is a downstream mediator of transforming growth factor-beta1-induced matrix metalloproteinase-9 expression and invasion of oral cancer cells. Journal of Cellular Biochemistry. 108: 726-36. PMID 19681038 DOI: 10.1002/Jcb.22309 |
0.738 |
|
2009 |
Moss NM, Liu Y, Johnson JJ, Debiase P, Jones J, Hudson LG, Munshi HG, Stack MS. Epidermal growth factor receptor-mediated membrane type 1 matrix metalloproteinase endocytosis regulates the transition between invasive versus expansive growth of ovarian carcinoma cells in three-dimensional collagen. Molecular Cancer Research : McR. 7: 809-20. PMID 19509114 DOI: 10.1158/1541-7786.Mcr-08-0571 |
0.476 |
|
2009 |
Moss NM, Wu YI, Liu Y, Munshi HG, Stack MS. Modulation of the membrane type 1 matrix metalloproteinase cytoplasmic tail enhances tumor cell invasion and proliferation in three-dimensional collagen matrices. The Journal of Biological Chemistry. 284: 19791-9. PMID 19458085 DOI: 10.1074/Jbc.M109.020362 |
0.445 |
|
2008 |
Diamond ME, Sun L, Ottaviano AJ, Joseph MJ, Munshi HG. Differential growth factor regulation of N-cadherin expression and motility in normal and malignant oral epithelium. Journal of Cell Science. 121: 2197-207. PMID 18544635 DOI: 10.1242/Jcs.021782 |
0.409 |
|
2008 |
Sun L, Diamond ME, Ottaviano AJ, Joseph MJ, Ananthanarayan V, Munshi HG. Transforming growth factor-beta 1 promotes matrix metalloproteinase-9-mediated oral cancer invasion through snail expression. Molecular Cancer Research : McR. 6: 10-20. PMID 18234959 DOI: 10.1158/1541-7786.Mcr-07-0208 |
0.465 |
|
2008 |
Dangi-Garimella S, Munshi HG. A NOVEL MICRORNA SIGNALING CASCADE REGULATES PANCREATIC CANCER CELL INVASION IN COLLAGEN Pancreas. 37: 466-567. DOI: 10.1097/01.MPA.0000335439.14797.A8 |
0.407 |
|
2007 |
Wu YI, Munshi HG, Snipas SJ, Salvesen GS, Fridman R, Stack MS. Activation-coupled membrane-type 1 matrix metalloproteinase membrane trafficking. The Biochemical Journal. 407: 171-7. PMID 17650075 DOI: 10.1042/Bj20070552 |
0.396 |
|
2007 |
Joseph MJ, Ananthanarayanan V, Diamond ME, Sun L, Munshi HG. Role of slug in TGF-β1 mediated MMP-9 expression in human oral squamous cell cancer Journal of Clinical Oncology. 25: 21000-21000. DOI: 10.1200/Jco.2007.25.18_Suppl.21000 |
0.51 |
|
2006 |
Rizvi MA, Ghias K, Davies KM, Ma C, Weinberg F, Munshi HG, Krett NL, Rosen ST. Enzastaurin (LY317615), a protein kinase Cbeta inhibitor, inhibits the AKT pathway and induces apoptosis in multiple myeloma cell lines. Molecular Cancer Therapeutics. 5: 1783-9. PMID 16891464 DOI: 10.1158/1535-7163.Mct-05-0465 |
0.358 |
|
2006 |
Ottaviano AJ, Sun L, Ananthanarayanan V, Munshi HG. Extracellular matrix-mediated membrane-type 1 matrix metalloproteinase expression in pancreatic ductal cells is regulated by transforming growth factor-beta1. Cancer Research. 66: 7032-40. PMID 16849548 DOI: 10.1158/0008-5472.Can-05-4421 |
0.566 |
|
2006 |
Munshi HG, Stack MS. Reciprocal interactions between adhesion receptor signaling and MMP regulation. Cancer Metastasis Reviews. 25: 45-56. PMID 16680571 DOI: 10.1007/S10555-006-7888-7 |
0.477 |
|
2004 |
Munshi HG, Wu YI, Mukhopadhyay S, Ottaviano AJ, Sassano A, Koblinski JE, Platanias LC, Stack MS. Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis. The Journal of Biological Chemistry. 279: 39042-50. PMID 15247230 DOI: 10.1074/Jbc.M404958200 |
0.48 |
|
2004 |
Mukhopadhyay S, Munshi HG, Kambhampati S, Sassano A, Platanias LC, Stack MS. Calcium-induced matrix metalloproteinase 9 gene expression is differentially regulated by ERK1/2 and p38 MAPK in oral keratinocytes and oral squamous cell carcinoma. The Journal of Biological Chemistry. 279: 33139-46. PMID 15180997 DOI: 10.1074/Jbc.M405194200 |
0.465 |
|
2004 |
Wu YI, Munshi HG, Sen R, Snipas SJ, Salvesen GS, Fridman R, Stack MS. Glycosylation broadens the substrate profile of membrane type 1 matrix metalloproteinase. The Journal of Biological Chemistry. 279: 8278-89. PMID 14670950 DOI: 10.1074/Jbc.M311870200 |
0.435 |
|
2002 |
Ghosh S, Munshi HG, Sen R, Linz-McGillem LA, Goldman RD, Lorch J, Green KJ, Jones JC, Stack MS. Loss of adhesion-regulated proteinase production is correlated with invasive activity in oral squamous cell carcinoma. Cancer. 95: 2524-33. PMID 12467066 DOI: 10.1002/Cncr.10997 |
0.451 |
|
2002 |
Munshi HG, Wu YI, Ariztia EV, Stack MS. Calcium regulation of matrix metalloproteinase-mediated migration in oral squamous cell carcinoma cells. The Journal of Biological Chemistry. 277: 41480-8. PMID 12194986 DOI: 10.1074/Jbc.M207695200 |
0.456 |
|
2002 |
Munshi HG, Ghosh S, Mukhopadhyay S, Wu YI, Sen R, Green KJ, Stack MS. Proteinase suppression by E-cadherin-mediated cell-cell attachment in premalignant oral keratinocytes. The Journal of Biological Chemistry. 277: 38159-67. PMID 12138162 DOI: 10.1074/Jbc.M202384200 |
0.412 |
|
2002 |
Munshi HG, Stack MS. Analysis of matrix degradation. Methods in Cell Biology. 69: 195-205. PMID 12070993 DOI: 10.1016/S0091-679X(02)69013-2 |
0.404 |
|
2002 |
Munshi HG, Merajver SD, Valdez R, Baker LH, Cooney KA. Metastatic dedifferentiated chordoma with elevated beta-hCG: a case report. American Journal of Clinical Oncology. 25: 274-6. PMID 12040287 DOI: 10.1097/00000421-200206000-00014 |
0.326 |
|
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