Donna D. Zhang - Publications

Pharmacology & Toxicology University of Arizona, Tucson, AZ 
Toxicology, Molecular Biology, Cell Biology

116 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Schmidlin CJ, Shakya A, Dodson M, Chapman E, Zhang DD. The Intricacies of NRF2 Regulation in Cancer. Seminars in Cancer Biology. PMID 34020028 DOI: 10.1016/j.semcancer.2021.05.016  0.32
2021 Liu P, Dodson M, Li H, Schmidlin CJ, Shakya A, Wei Y, Garcia JG, Chapman E, Kiela PR, Zhang QY, White E, Ding X, Ooi A, Zhang DD. Non-canonical NRF2 activation promotes a pro-diabetic shift in hepatic glucose metabolism. Molecular Metabolism. 101243. PMID 33933676 DOI: 10.1016/j.molmet.2021.101243  0.36
2021 Schmidlin CJ, Tian W, Dodson M, Chapman E, Zhang DD. FAM129B-dependent activation of NRF2 promotes an invasive phenotype in BRAF mutant melanoma cells. Molecular Carcinogenesis. PMID 33684228 DOI: 10.1002/mc.23295  0.36
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Zhang DD, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.32
2020 Liu P, Luo G, Dodson M, Schmidlin CJ, Wei Y, Kerimoglu B, Ooi A, Chapman E, Garcia JG, Zhang DD. The NRF2-LOC344887 signaling axis suppresses pulmonary fibrosis. Redox Biology. 38: 101766. PMID 33126057 DOI: 10.1016/j.redox.2020.101766  0.32
2020 Schmidlin CJ, Zeng T, Liu P, Wei Y, Dodson M, Chapman E, Zhang DD. Chronic arsenic exposure enhances metastatic potential via NRF2-mediated upregulation of SOX9. Toxicology and Applied Pharmacology. 115138. PMID 32682831 DOI: 10.1016/J.Taap.2020.115138  0.32
2020 Anandhan A, Dodson M, Schmidlin CJ, Liu P, Zhang DD. Breakdown of an Ironclad Defense System: The Critical Role of NRF2 in Mediating Ferroptosis. Cell Chemical Biology. 27: 436-447. PMID 32275864 DOI: 10.1016/J.Chembiol.2020.03.011  0.32
2020 Liu P, Dodson M, Fang D, Chapman E, Zhang DD. NRF2 negatively regulates primary ciliogenesis and hedgehog signaling. Plos Biology. 18: e3000620. PMID 32053600 DOI: 10.1371/Journal.Pbio.3000620  0.32
2019 Liu P, Kerins MJ, Tian W, Neupane D, Zhang DD, Ooi A. Differential and overlapping targets of the transcriptional regulators NRF1, NRF2, and NRF3 in human cells. The Journal of Biological Chemistry. PMID 31628195 DOI: 10.1074/Jbc.Ra119.009591  0.36
2019 Liu P, Tian W, Tao S, Tillotson J, Wijeratne EMK, Gunatilaka AAL, Zhang DD, Chapman E. Non-covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation. Cell Chemical Biology. PMID 31402317 DOI: 10.1016/J.Chembiol.2019.07.011  0.36
2019 Kerins MJ, Liu P, Tian W, Mannheim W, Zhang D, Ooi A. Genome wide CRISPR screen reveals autophagy disruption as the convergence mechanism that regulates the NRF2 transcription factor. Molecular and Cellular Biology. PMID 31010806 DOI: 10.1128/Mcb.00037-19  0.36
2019 Liu P, de la Vega MR, Dodson M, Yue F, Shi B, Fang D, Chapman E, Liu L, Zhang DD. Spermidine confers liver protection by enhancing NRF2 signaling through a MAP1S-mediated non-canonical mechanism. Hepatology (Baltimore, Md.). PMID 30873635 DOI: 10.1002/Hep.30616  0.32
2019 Tao S, Wang S, Moghaddam SJ, Ooi A, Chapman E, Wong PK, Zhang DD. Correction: Oncogenic KRAS Confers Chemoresistance by Upregulating NRF2. Cancer Research. 79: 1015. PMID 30824678 DOI: 10.1158/0008-5472.Can-19-0070  0.44
2019 Xiao Y, Riahi R, Torab P, Zhang DD, Wong PK. Collective Cell Migration in 3D Epithelial Wound Healing. Acs Nano. PMID 30758172 DOI: 10.1021/Acsnano.8B06305  0.44
2019 Dodson M, Castro-Portuguez R, Zhang DD. NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis. Redox Biology. 101107. PMID 30692038 DOI: 10.1016/J.Redox.2019.101107  0.32
2018 Liu P, Rojo de la Vega M, Sammani S, Mascarenhas JB, Kerins M, Dodson M, Sun X, Wang T, Ooi A, Garcia JGN, Zhang DD. RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE-dependent repression. Proceedings of the National Academy of Sciences of the United States of America. PMID 30309964 DOI: 10.1073/Pnas.1812125115  0.32
2018 Dodson M, de la Vega MR, Cholanians AB, Schmidlin CJ, Chapman E, Zhang DD. Modulating NRF2 in Disease: Timing Is Everything. Annual Review of Pharmacology and Toxicology. PMID 30256716 DOI: 10.1146/Annurev-Pharmtox-010818-021856  0.32
2018 Dodson M, Liu P, Jiang T, Ambrose AJ, Luo G, Rojo de la Vega M, Cholanians AB, Wong PK, Chapman E, Zhang DD. Increased O-GlcNAcylation of SNAP29 drives arsenic-induced autophagic dysfunction. Molecular and Cellular Biology. PMID 29507186 DOI: 10.1128/Mcb.00595-17  0.52
2018 Dodson M, de la Vega MR, Harder B, Castro-Portuguez R, Rodrigues SD, Wong PK, Chapman E, Zhang DD. Low-level arsenic causes proteotoxic stress and not oxidative stress. Toxicology and Applied Pharmacology. 341: 106-113. PMID 29408041 DOI: 10.1016/J.Taap.2018.01.014  0.44
2018 Wang S, Xiao Y, Zhang DD, Wong PK. A gapmer aptamer nanobiosensor for real-time monitoring of transcription and translation in single cells. Biomaterials. 156: 56-64. PMID 29190498 DOI: 10.1016/J.Biomaterials.2017.11.026  0.44
2017 Wang S, Sun J, Xiao Y, Lu Y, Zhang DD, Wong PK. Intercellular Tension Negatively Regulates Angiogenic Sprouting of Endothelial Tip Cells via Notch1-Dll4 Signaling. Advanced Biosystems. 1. PMID 30662935 DOI: 10.1002/adbi.201600019  0.44
2017 Tian W, Rojo de la Vega M, Schmidlin CJ, Ooi A, Zhang DD. Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2). The Journal of Biological Chemistry. PMID 29255090 DOI: 10.1074/Jbc.Ra117.000428  0.36
2017 Dodson M, Zhang DD. Non-canonical activation of NRF2: New insights and its relevance to disease. Current Pathobiology Reports. 5: 171-176. PMID 29082113 DOI: 10.1007/S40139-017-0131-0  0.32
2017 Long M, Li X, Li L, Dodson M, Zhang DD, Zheng H. Multifunctional p62 Effects Underlie Diverse Metabolic Diseases. Trends in Endocrinology and Metabolism: Tem. PMID 28966079 DOI: 10.1016/J.Tem.2017.09.001  0.32
2017 Tao S, Liu P, Luo G, Rojo de la Vega M, Chen H, Wu T, Tillotson J, Chapman E, Zhang DD. p97 Negatively Regulates NRF2 by Extracting Ubiquitylated NRF2 from the KEAP1-CUL3 E3 Complex. Molecular and Cellular Biology. PMID 28115426 DOI: 10.1128/Mcb.00660-16  0.52
2017 Bao L, Wu J, Dodson M, Rojo de la Vega EM, Ning Y, Zhang Z, Yao M, Zhang DD, Xu C, Yi X. ABCF2, an Nrf2 target gene, contributes to cisplatin resistance in ovarian cancer cells. Molecular Carcinogenesis. PMID 28112439 DOI: 10.1002/Mc.22615  0.36
2016 de la Vega MR, Dodson M, Chapman E, Zhang DD. NRF2-targeted therapeutics: New targets and modes of NRF2 regulation. Current Opinion in Toxicology. 1: 62-70. PMID 29082352 DOI: 10.1016/J.Cotox.2016.10.005  0.32
2016 Harder B, Tian W, La Clair JJ, Tan AC, Ooi A, Chapman E, Zhang DD. Brusatol overcomes chemoresistance through inhibition of protein translation. Molecular Carcinogenesis. PMID 28019675 DOI: 10.1002/Mc.22609  0.36
2016 Wang S, Sun J, Zhang DD, Wong PK. A nanobiosensor for dynamic single cell analysis during microvascular self-organization. Nanoscale. PMID 27547924 DOI: 10.1039/C6Nr03907C  0.44
2016 Xu Y, Zhao F, Qiu Q, Chen K, Wei J, Kong Q, Gao B, Melo-Cardenas J, Zhang B, Zhang J, Song J, Zhang DD, Zhang J, Fan Y, Li H, et al. The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity. Nature Communications. 7: 12073. PMID 27417417 DOI: 10.1038/Ncomms12073  0.48
2016 de la Vega MR, Dodson M, Gross C, Manzour H, Lantz RC, Chapman E, Wang T, Black SM, Garcia JG, Zhang DD. Role of Nrf2 and Autophagy in Acute Lung Injury. Current Pharmacology Reports. 2: 91-101. PMID 27313980 DOI: 10.1007/S40495-016-0053-2  0.32
2016 Sun J, Hoying JB, Deymier PA, Zhang DD, Wong PK. Cellular Architecture Regulates Collective Calcium Signaling and Cell Contractility. Plos Computational Biology. 12: e1004955. PMID 27196735 DOI: 10.1371/Journal.Pcbi.1004955  0.44
2016 Wang H, Liu X, Long M, Huang Y, Zhang L, Zhang R, Zheng Y, Liao X, Wang Y, Liao Q, Li W, Tang Z, Tong Q, Wang X, Fang F, ... ... Zhang DD, et al. NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis. Science Translational Medicine. 8: 334ra51. PMID 27075625 DOI: 10.1126/Scitranslmed.Aad6095  0.48
2016 Tang Q, Liang M, Lu Y, Wong PK, Wilmink GJ, Zhang D, Xin H. Microfluidic Devices for Terahertz Spectroscopy of Live Cells Toward Lab-on-a-Chip Applications. Sensors (Basel, Switzerland). 16. PMID 27049392 DOI: 10.3390/S16040476  0.48
2016 Chen W, Li S, Li J, Zhou W, Wu S, Xu S, Cui K, Zhang DD, Liu B. Artemisitene activates the Nrf2-dependent antioxidant response and protects against bleomycin-induced lung injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27006451 DOI: 10.1096/Fj.201500109R  0.52
2016 Wang Y, Wang Y, Zhang Z, Park JY, Guo D, Liao H, Yi X, Zheng Y, Zhang D, Chambers SK, Zheng W. Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-AKR1C1 pathway. Oncotarget. PMID 26824415 DOI: 10.18632/Oncotarget.7004  0.48
2015 Long M, Rojo de la Vega M, Wen Q, Bharara M, Jiang T, Zhang R, Zhou S, Wong PK, Wondrak GT, Zheng H, Zhang DD. An essential role of NRF2 in diabetic wound healing. Diabetes. PMID 26718502 DOI: 10.2337/Db15-0564  0.48
2015 Qian Z, Zhou T, Gurguis CI, Xu X, Wen Q, Lv J, Fang F, Hecker L, Cress AE, Natarajan V, Jacobson JR, Zhang DD, Garcia JG, Wang T. Nuclear factor, erythroid 2-like 2-associated molecular signature predicts lung cancer survival. Scientific Reports. 5: 16889. PMID 26596768 DOI: 10.1038/Srep16889  0.48
2015 Harder B, Jiang T, Wu T, Tao S, de la Vega MR, Tian W, Chapman E, Zhang DD. Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention. Biochemical Society Transactions. 43: 680-6. PMID 26551712 DOI: 10.1042/Bst20150020  0.52
2015 Wang S, Riahi R, Li N, Zhang DD, Wong PK. Biosensors: Single Cell Nanobiosensors for Dynamic Gene Expression Profiling in Native Tissue Microenvironments (Adv. Mater. 39/2015). Advanced Materials (Deerfield Beach, Fla.). 27: 6076. PMID 26466935 DOI: 10.1002/Adma.201570265  0.44
2015 Tao S, Park SL, de la Vega MR, Zhang DD, Wondrak GT. Systemic administration of the apocarotenoid bixin protects skin against solar UV-induced damage through activation of NRF2. Free Radical Biology & Medicine. PMID 26456052 DOI: 10.1016/J.Freeradbiomed.2015.08.028  0.48
2015 Wang S, Riahi R, Li N, Zhang DD, Wong PK. Single Cell Nanobiosensors for Dynamic Gene Expression Profiling in Native Tissue Microenvironments. Advanced Materials (Deerfield Beach, Fla.). PMID 26314800 DOI: 10.1002/Adma.201502814  0.48
2015 Jiang T, Harder B, Vega MR, Wong PK, Chapman E, Zhang DD. p62 links autophagy and Nrf2 signaling. Free Radical Biology & Medicine. PMID 26117325 DOI: 10.1016/J.Freeradbiomed.2015.06.014  0.52
2015 Tao S, Tillotson J, Wijeratne EM, Xu YM, Kang M, Wu T, Lau EC, Mesa C, Mason DJ, Brown RV, La Clair JJ, Gunatilaka AA, Zhang DD, Chapman E. Withaferin A Analogs That Target the AAA+ Chaperone p97. Acs Chemical Biology. PMID 26006219 DOI: 10.1021/Acschembio.5B00367  0.48
2015 Shen T, Jiang T, Long M, Chen J, Ren D, Wong PK, Chapman E, Zhou B, Zhang DD. A curcumin derivative that inhibits vinyl carbamate-induced lung carcinogenesis via activation of the Nrf2 protective response. Antioxidants & Redox Signaling. PMID 25891177 DOI: 10.1089/Ars.2014.6074  0.48
2015 Riahi R, Sun J, Wang S, Long M, Zhang DD, Wong PK. Notch1-Dll4 signalling and mechanical force regulate leader cell formation during collective cell migration. Nature Communications. 6: 6556. PMID 25766473 DOI: 10.1038/Ncomms7556  0.48
2015 Long M, Tao S, Rojo de la Vega M, Jiang T, Wen Q, Park SL, Zhang DD, Wondrak GT. Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde. Cancer Prevention Research (Philadelphia, Pa.). 8: 444-54. PMID 25712056 DOI: 10.1158/1940-6207.Capr-14-0359  0.48
2015 Canet MJ, Merrell MD, Harder BG, Maher JM, Wu T, Lickteig AJ, Jackson JP, Zhang DD, Yamamoto M, Cherrington NJ. Identification of a functional antioxidant response element within the eighth intron of the human ABCC3 gene. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 93-9. PMID 25349122 DOI: 10.1124/Dmd.114.060103  0.48
2015 Bao L, Jaramillo MC, Zhang Z, Zheng Y, Yao M, Zhang DD, Yi X. Induction of autophagy contributes to cisplatin resistance in human ovarian cancer cells. Molecular Medicine Reports. 11: 91-8. PMID 25322694 DOI: 10.3892/Mmr.2014.2671  0.48
2015 Harder B, Jiang T, Wu T, Tao S, De La Vega MR, Tian W, Chapman E, Zhang DD. Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention Biochemical Society Transactions. 43: 680-686. DOI: 10.1042/BST20150020  0.48
2014 Nam KH, Jamilpour N, Mfoumou E, Wang FY, Zhang DD, Wong PK. Probing mechanoregulation of neuronal differentiation by plasma lithography patterned elastomeric substrates. Scientific Reports. 4: 6965. PMID 25376886 DOI: 10.1038/Srep06965  0.48
2014 Tao S, Wang S, Moghaddam SJ, Ooi A, Chapman E, Wong PK, Zhang DD. Oncogenic KRAS confers chemoresistance by upregulating NRF2. Cancer Research. 74: 7430-41. PMID 25339352 DOI: 10.1158/0008-5472.Can-14-1439  0.48
2014 Wu T, Harder BG, Wong PK, Lang JE, Zhang DD. Oxidative stress, mammospheres and Nrf2-new implication for breast cancer therapy? Molecular Carcinogenesis. PMID 25154499 DOI: 10.1002/Mc.22202  0.48
2014 Kang MJ, Wu T, Wijeratne EM, Lau EC, Mason DJ, Mesa C, Tillotson J, Zhang DD, Gunatilaka AA, La Clair JJ, Chapman E. Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action. Chembiochem : a European Journal of Chemical Biology. 15: 2125-31. PMID 25125376 DOI: 10.1002/Cbic.201402258  0.52
2014 Bao LJ, Jaramillo MC, Zhang ZB, Zheng YX, Yao M, Zhang DD, Yi XF. Nrf2 induces cisplatin resistance through activation of autophagy in ovarian carcinoma. International Journal of Clinical and Experimental Pathology. 7: 1502-13. PMID 24817946  0.48
2014 Riahi R, Wang S, Long M, Li N, Chiou PY, Zhang DD, Wong PK. Mapping photothermally induced gene expression in living cells and tissues by nanorod-locked nucleic acid complexes. Acs Nano. 8: 3597-605. PMID 24645754 DOI: 10.1021/Nn500107G  0.48
2014 Wu T, Zhao F, Gao B, Tan C, Yagishita N, Nakajima T, Wong PK, Chapman E, Fang D, Zhang DD. Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis. Genes & Development. 28: 708-22. PMID 24636985 DOI: 10.1101/Gad.238246.114  0.48
2014 Riahi R, Long M, Yang Y, Dean Z, Zhang DD, Slepian MJ, Wong PK. Single cell gene expression analysis in injury-induced collective cell migration. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 192-202. PMID 24336811 DOI: 10.1039/C3Ib40095F  0.48
2014 Wu T, Wang XJ, Tian W, Jaramillo MC, Lau A, Zhang DD. Poly(ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription. Free Radical Biology & Medicine. 67: 69-80. PMID 24140708 DOI: 10.1016/J.Freeradbiomed.2013.10.806  0.88
2014 Jiang T, Tian F, Zheng H, Whitman SA, Lin Y, Zhang Z, Zhang N, Zhang DD. Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-κB-mediated inflammatory response. Kidney International. 85: 333-43. PMID 24025640 DOI: 10.1038/Ki.2013.343  0.48
2013 Jaramillo MC, Zhang DD. The emerging role of the Nrf2-Keap1 signaling pathway in cancer. Genes & Development. 27: 2179-91. PMID 24142871 DOI: 10.1101/Gad.225680.113  0.48
2013 Chen W, Wang H, Tao S, Zheng Y, Wu W, Lian F, Jaramillo M, Fang D, Zhang DD. Tumor protein translationally controlled 1 is a p53 target gene that promotes cell survival. Cell Cycle (Georgetown, Tex.). 12: 2321-8. PMID 24067374 DOI: 10.4161/Cc.25404  0.52
2013 Qiu Q, Zheng Z, Chang L, Zhao YS, Tan C, Dandekar A, Zhang Z, Lin Z, Gui M, Li X, Zhang T, Kong Q, Li H, Chen S, Chen A, ... ... Zhang D, et al. Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis. The Embo Journal. 32: 2477-90. PMID 23942232 DOI: 10.1038/Emboj.2013.183  0.48
2013 Whitman SA, Long M, Wondrak GT, Zheng H, Zhang DD. Nrf2 modulates contractile and metabolic properties of skeletal muscle in streptozotocin-induced diabetic atrophy. Experimental Cell Research. 319: 2673-83. PMID 23896025 DOI: 10.1016/J.Yexcr.2013.07.015  0.48
2013 Riahi R, Dean Z, Wu TH, Teitell MA, Chiou PY, Zhang DD, Wong PK. Detection of mRNA in living cells by double-stranded locked nucleic acid probes. The Analyst. 138: 4777-85. PMID 23772441 DOI: 10.1039/C3An00722G  0.48
2013 Villeneuve NF, Tian W, Wu T, Sun Z, Lau A, Chapman E, Fang D, Zhang DD. USP15 negatively regulates Nrf2 through deubiquitination of Keap1. Molecular Cell. 51: 68-79. PMID 23727018 DOI: 10.1016/J.Molcel.2013.04.022  0.48
2013 Ji L, Li H, Gao P, Shang G, Zhang DD, Zhang N, Jiang T. Nrf2 pathway regulates multidrug-resistance-associated protein 1 in small cell lung cancer. Plos One. 8: e63404. PMID 23667609 DOI: 10.1371/Journal.Pone.0063404  0.52
2013 Lau A, Zheng Y, Tao S, Wang H, Whitman SA, White E, Zhang DD. Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner. Molecular and Cellular Biology. 33: 2436-46. PMID 23589329 DOI: 10.1128/Mcb.01748-12  0.4
2013 Wu W, Qiu Q, Wang H, Whitman SA, Fang D, Lian F, Zhang DD. Nrf2 is crucial to graft survival in a rodent model of heart transplantation. Oxidative Medicine and Cellular Longevity. 2013: 919313. PMID 23533698 DOI: 10.1155/2013/919313  0.48
2013 Lu Y, Gao J, Zhang DD, Gau V, Liao JC, Wong PK. Single cell antimicrobial susceptibility testing by confined microchannels and electrokinetic loading. Analytical Chemistry. 85: 3971-6. PMID 23445209 DOI: 10.1021/Ac4004248  0.48
2013 Tao S, Zheng Y, Lau A, Jaramillo MC, Chau BT, Lantz RC, Wong PK, Wondrak GT, Zhang DD. Tanshinone I activates the Nrf2-dependent antioxidant response and protects against As(III)-induced lung inflammation in vitro and in vivo. Antioxidants & Redox Signaling. 19: 1647-61. PMID 23394605 DOI: 10.1089/Ars.2012.5117  0.48
2013 Lau A, Whitman SA, Jaramillo MC, Zhang DD. Arsenic-mediated activation of the Nrf2-Keap1 antioxidant pathway. Journal of Biochemical and Molecular Toxicology. 27: 99-105. PMID 23188707 DOI: 10.1002/Jbt.21463  0.48
2013 Lau A, Tian W, Whitman SA, Zhang DD. The predicted molecular weight of Nrf2: it is what it is not. Antioxidants & Redox Signaling. 18: 91-3. PMID 22703241 DOI: 10.1089/Ars.2012.4754  0.48
2012 Wang F, Tian F, Whitman SA, Zhang DD, Nishinaka T, Zhang N, Jiang T. Regulation of transforming growth factor β1-dependent aldose reductase expression by the Nrf2 signal pathway in human mesangial cells. European Journal of Cell Biology. 91: 774-81. PMID 22951256 DOI: 10.1016/J.Ejcb.2012.07.004  0.48
2012 Bray K, Mathew R, Lau A, Kamphorst JJ, Fan J, Chen J, Chen HY, Ghavami A, Stein M, DiPaola RS, Zhang D, Rabinowitz JD, White E. Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition. Plos One. 7: e41831. PMID 22848625 DOI: 10.1371/Journal.Pone.0041831  0.48
2012 Chen W, Jiang T, Wang H, Tao S, Lau A, Fang D, Zhang DD. Does Nrf2 contribute to p53-mediated control of cell survival and death? Antioxidants & Redox Signaling. 17: 1670-5. PMID 22559194 DOI: 10.1089/Ars.2012.4674  0.88
2012 Hu Q, Zhang DD, Wang L, Lou H, Ren D. Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 50: 1927-32. PMID 22465804 DOI: 10.1016/J.Fct.2012.03.059  0.52
2012 Riahi R, Yang Y, Zhang DD, Wong PK. Advances in wound-healing assays for probing collective cell migration. Journal of Laboratory Automation. 17: 59-65. PMID 22357609 DOI: 10.1177/2211068211426550  0.48
2012 Ma J, Cai H, Wu T, Sobhian B, Huo Y, Alcivar A, Mehta M, Cheung KL, Ganesan S, Kong AN, Zhang DD, Xia B. PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function. Molecular and Cellular Biology. 32: 1506-17. PMID 22331464 DOI: 10.1128/Mcb.06271-11  0.48
2012 Bray K, Mathew R, Lau A, Kamphorst JJ, Fan J, Chen J, Chen H, Ghavami A, Stein M, DiPaola RS, Zhang D, Rabinowitz JD, White E. Cell death induced by autophagy and mTOR inhibition is RIPK-dependent necroptosis. Plos One. DOI: 10.1371/Journal.Pone.0041831.G003  0.88
2011 Zheng H, Whitman SA, Wu W, Wondrak GT, Wong PK, Fang D, Zhang DD. Therapeutic potential of Nrf2 activators in streptozotocin-induced diabetic nephropathy. Diabetes. 60: 3055-66. PMID 22025779 DOI: 10.2337/Db11-0807  0.48
2011 Sun Z, Wu T, Zhao F, Lau A, Birch CM, Zhang DD. KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response. Molecular and Cellular Biology. 31: 1800-11. PMID 21383067 DOI: 10.1128/Mcb.05036-11  0.88
2011 Ren D, Villeneuve NF, Jiang T, Wu T, Lau A, Toppin HA, Zhang DD. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Proceedings of the National Academy of Sciences of the United States of America. 108: 1433-8. PMID 21205897 DOI: 10.1073/Pnas.1014275108  0.88
2010 Chen HC, Chen CH, Gau V, Zhang DD, Liao JC, Wang FY, Wong PK. Statistical metamodeling for revealing synergistic antimicrobial interactions. Plos One. 5: e15472. PMID 21124958 DOI: 10.1371/Journal.Pone.0015472  0.48
2010 Wondrak GT, Villeneuve NF, Lamore SD, Bause AS, Jiang T, Zhang DD. The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells. Molecules (Basel, Switzerland). 15: 3338-55. PMID 20657484 DOI: 10.3390/Molecules15053338  0.88
2010 Hur W, Sun Z, Jiang T, Mason DE, Peters EC, Zhang DD, Luesch H, Schultz PG, Gray NS. A small-molecule inducer of the antioxidant response element. Chemistry & Biology. 17: 537-47. PMID 20534351 DOI: 10.1016/J.Chembiol.2010.03.013  0.48
2010 Jiang T, Chen N, Zhao F, Wang XJ, Kong B, Zheng W, Zhang DD. High levels of Nrf2 determine chemoresistance in type II endometrial cancer. Cancer Research. 70: 5486-96. PMID 20530669 DOI: 10.1158/0008-5472.Can-10-0713  0.52
2010 Villeneuve NF, Lau A, Zhang DD. Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases. Antioxidants & Redox Signaling. 13: 1699-712. PMID 20486766 DOI: 10.1089/Ars.2010.3211  0.88
2010 Lau A, Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD. A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62. Molecular and Cellular Biology. 30: 3275-85. PMID 20421418 DOI: 10.1128/Mcb.00248-10  0.88
2010 Jiang T, Huang Z, Lin Y, Zhang Z, Fang D, Zhang DD. The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy. Diabetes. 59: 850-60. PMID 20103708 DOI: 10.2337/Db09-1342  0.52
2010 Chen CH, Lu Y, Sin ML, Mach KE, Zhang DD, Gau V, Liao JC, Wong PK. Antimicrobial susceptibility testing using high surface-to-volume ratio microchannels. Analytical Chemistry. 82: 1012-9. PMID 20055494 DOI: 10.1021/Ac9022764  0.48
2009 Gidwani V, Riahi R, Zhang DD, Wong PK. Hybridization kinetics of double-stranded DNA probes for rapid molecular analysis Analyst. 134: 1675-1681. PMID 20448937 DOI: 10.1039/B906077D  0.48
2009 Villeneuve NF, Sun Z, Chen W, Zhang DD. Nrf2 and p21 regulate the fine balance between life and death by controlling ROS levels. Cell Cycle (Georgetown, Tex.). 8: 3255-6. PMID 19806015 DOI: 10.4161/Cc.8.20.9565  0.88
2009 Sun Z, Huang Z, Zhang DD. Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response. Plos One. 4: e6588. PMID 19668370 DOI: 10.1371/Journal.Pone.0006588  0.52
2009 Zhao F, Wu T, Lau A, Jiang T, Huang Z, Wang XJ, Chen W, Wong PK, Zhang DD. Nrf2 promotes neuronal cell differentiation. Free Radical Biology & Medicine. 47: 867-79. PMID 19573594 DOI: 10.1016/J.Freeradbiomed.2009.06.029  0.48
2009 Chen W, Sun Z, Wang XJ, Jiang T, Huang Z, Fang D, Zhang DD. Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response. Molecular Cell. 34: 663-73. PMID 19560419 DOI: 10.1016/J.Molcel.2009.04.029  0.52
2009 Jiang T, Huang Z, Chan JY, Zhang DD. Nrf2 protects against As(III)-induced damage in mouse liver and bladder. Toxicology and Applied Pharmacology. 240: 8-14. PMID 19538980 DOI: 10.1016/J.Taap.2009.06.010  0.52
2009 Wang XJ, Zhang DD. Ectodermal-neural cortex 1 down-regulates Nrf2 at the translational level. Plos One. 4: e5492. PMID 19424503 DOI: 10.1371/Journal.Pone.0005492  0.36
2009 Sun Z, Chin YE, Zhang DD. Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response. Molecular and Cellular Biology. 29: 2658-72. PMID 19273602 DOI: 10.1128/Mcb.01639-08  0.52
2008 Lau A, Villeneuve NF, Sun Z, Wong PK, Zhang DD. Dual roles of Nrf2 in cancer Pharmacological Research. 58: 262-270. PMID 18838122 DOI: 10.1016/J.Phrs.2008.09.003  0.48
2008 Du Y, Villeneuve NF, Wang XJ, Sun Z, Chen W, Li J, Lou H, Wong PK, Zhang DD. Oridonin confers protection against arsenic-induced toxicity through activation of the Nrf2-mediated defensive response. Environmental Health Perspectives. 116: 1154-61. PMID 18795156 DOI: 10.1289/Ehp.11464  0.48
2008 Meserve D, Wang Z, Zhang DD, Wong PK. A double-stranded molecular probe for homogeneous nucleic acid analysis. The Analyst. 133: 1013-9. PMID 18645642 DOI: 10.1039/B804853C  0.44
2008 Wang Z, Gidwani V, Zhang DD, Wong PK. Separation-free detection of nuclear factor kappa B with double-stranded molecular probes. The Analyst. 133: 998-1000. PMID 18645638 DOI: 10.1039/B809113G  0.44
2008 Wondrak GT, Cabello CM, Villeneuve NF, Zhang S, Ley S, Li Y, Sun Z, Zhang DD. Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress. Free Radical Biology & Medicine. 45: 385-95. PMID 18482591 DOI: 10.1016/J.Freeradbiomed.2008.04.023  0.88
2008 Wang XJ, Sun Z, Chen W, Li Y, Villeneuve NF, Zhang DD. Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction. Toxicology and Applied Pharmacology. 230: 383-9. PMID 18417180 DOI: 10.1016/J.Taap.2008.03.003  0.88
2008 Wang XJ, Sun Z, Villeneuve NF, Zhang S, Zhao F, Li Y, Chen W, Yi X, Zheng W, Wondrak GT, Wong PK, Zhang DD. Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2. Carcinogenesis. 29: 1235-43. PMID 18413364 DOI: 10.1093/Carcin/Bgn095  0.88
2007 Wang XJ, Sun Z, Chen W, Eblin KE, Gandolfi JA, Zhang DD. Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity. Toxicology and Applied Pharmacology. 225: 206-13. PMID 17765279 DOI: 10.1016/J.Taap.2007.07.016  0.48
2007 Sun Z, Zhang S, Chan JY, Zhang DD. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2. Molecular and Cellular Biology. 27: 6334-49. PMID 17636022 DOI: 10.1128/Mcb.00630-07  0.52
2005 Ansell PJ, Lo SC, Newton LG, Espinosa-Nicholas C, Zhang DD, Liu JH, Hannink M, Lubahn DB. Repression of cancer protective genes by 17beta-estradiol: ligand-dependent interaction between human Nrf2 and estrogen receptor alpha. Molecular and Cellular Endocrinology. 243: 27-34. PMID 16198475 DOI: 10.1016/J.Mce.2005.08.002  0.48
2005 Zhang DD, Lo SC, Sun Z, Habib GM, Lieberman MW, Hannink M. Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway. The Journal of Biological Chemistry. 280: 30091-9. PMID 15983046 DOI: 10.1074/Jbc.M501279200  0.48
2004 Li X, Zhang D, Hannink M, Beamer LJ. Crystallization and initial crystallographic analysis of the Kelch domain from human Keap1. Acta Crystallographica. Section D, Biological Crystallography. 60: 2346-8. PMID 15583386 DOI: 10.1107/S0907444904024825  0.48
2004 Zhang DD, Lo SC, Cross JV, Templeton DJ, Hannink M. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Molecular and Cellular Biology. 24: 10941-53. PMID 15572695 DOI: 10.1128/Mcb.24.24.10941-10953.2004  0.48
2004 Li X, Zhang D, Hannink M, Beamer LJ. Crystal structure of the Kelch domain of human Keap1. The Journal of Biological Chemistry. 279: 54750-8. PMID 15475350 DOI: 10.1074/Jbc.M410073200  0.48
2003 Zhang DD, Hannink M. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Molecular and Cellular Biology. 23: 8137-51. PMID 14585973 DOI: 10.1128/Mcb.23.22.8137-8151.2003  0.48
2003 Cullinan SB, Zhang D, Hannink M, Arvisais E, Kaufman RJ, Diehl JA. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Molecular and Cellular Biology. 23: 7198-209. PMID 14517290 DOI: 10.1128/Mcb.23.20.7198-7209.2003  0.48
2000 Sachdev S, Bagchi S, Zhang DD, Mings AC, Hannink M. Nuclear import of IkappaBalpha is accomplished by a ran-independent transport pathway. Molecular and Cellular Biology. 20: 1571-82. PMID 10669735 DOI: 10.1128/Mcb.20.5.1571-1582.2000  0.48
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