Carl D. Novina - Publications

Affiliations: 
Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Area:
Genetics, Molecular Biology, Cell Biology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Morelli E, Fulciniti M, Samur MK, Ribeiro C, Wert-Lamas L, Henninger JE, Gulla A, Aktas Samur A, Todoerti K, Talluri S, Park WD, Federico C, Scionti F, Amodio N, Bianchi G, ... ... Novina CD, et al. A MIR17HG-derived Long Noncoding RNA Provides an Essential Chromatin Scaffold for Protein Interaction and Myeloma Growth. Blood. PMID 36126301 DOI: 10.1182/blood.2022016892  0.306
2020 Schmidt K, Weidmann CA, Hilimire TA, Yee E, Hatfield BM, Schneekloth JS, Weeks KM, Novina CD. Targeting the Oncogenic Long Non-coding RNA SLNCR1 by Blocking Its Sequence-Specific Binding to the Androgen Receptor. Cell Reports. 30: 541-554.e5. PMID 31940495 DOI: 10.1016/J.Celrep.2019.12.011  0.339
2019 Joyce CE, Saadatpour A, Ruiz-Gutierrez M, Bolukbasi OV, Jiang L, Thomas DD, Young S, Hofmann I, Sieff C, Myers KC, Whangbo J, Libermann TA, Nusbaum C, Yuan GC, Shimamura A, ... Novina CD, et al. TGFβ signaling underlies hematopoietic dysfunction and bone marrow failure in Shwachman-Diamond Syndrome. The Journal of Clinical Investigation. 130. PMID 31211692 DOI: 10.1172/Jci125375  0.305
2019 Schmidt K, Carroll JS, Yee E, Thomas DD, Wert-Lamas L, Neier SC, Sheynkman G, Ritz J, Novina CD. The lncRNA SLNCR Recruits the Androgen Receptor to EGR1-Bound Genes in Melanoma and Inhibits Expression of Tumor Suppressor p21. Cell Reports. 27: 2493-2507.e4. PMID 31116991 DOI: 10.1016/J.Celrep.2019.04.101  0.333
2017 Hsu JH, Hubbell-Engler B, Adelmant G, Huang J, Joyce CE, Vazquez F, Weir BA, Montgomery P, Tsherniak A, Giacomelli AO, Perry JA, Trowbridge J, Fujiwara Y, Cowley GS, Xie H, ... ... Novina CD, et al. Prmt1-mediated translation regulation is a crucial vulnerability of cancer. Cancer Research. PMID 28655788 DOI: 10.1158/0008-5472.Can-17-0216  0.357
2017 Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J, Golub TR, Cantor H, Sharpe AH, Novina CD, Wucherpfennig KW. The microRNA miR-31 inhibits CD8(+) T cell function in chronic viral infection. Nature Immunology. PMID 28530712 DOI: 10.1038/Ni.3755  0.375
2016 Joyce CE, Yanez AG, Mori A, Yoda A, Carroll JS, Novina CD. Differential regulation of the melanoma proteome by eIF4A1 and eIF4E. Cancer Research. PMID 27879264 DOI: 10.1158/0008-5472.Can-16-1298  0.375
2016 Schmidt K, Joyce CE, Buquicchio F, Brown A, Ritz J, Distel RJ, Yoon CH, Novina CD. The lncRNA SLNCR1 Mediates Melanoma Invasion through a Conserved SRA1-like Region. Cell Reports. PMID 27210747 DOI: 10.1016/J.Celrep.2016.04.018  0.341
2015 Traeger LL, Volkening JD, Moffett H, Gallant JR, Chen PH, Novina CD, Phillips GN, Anand R, Wells GB, Pinch M, Güth R, Unguez GA, Albert JS, Zakon H, Sussman MR, et al. Unique patterns of transcript and miRNA expression in the South American strong voltage electric eel (Electrophorus electricus). Bmc Genomics. 16: 243. PMID 25887781 DOI: 10.1186/S12864-015-1288-8  0.433
2015 Joyce CE, McGuinness M, Schneider RK, Fleming MD, Campagna DR, Schmidt PJ, Ebert BL, Novina CD, Sieff CA. A Novel Conditional Knockout of the Diamond Blackfan Anemia Gene Rpl11 Shows Failure of Erythropoiesis, a Marked Increase in BFU-E Progenitors By Phenotype That Proliferate Poorly in Culture, and Activation of p53 Target Genes Blood. 126: 1205-1205. DOI: 10.1182/Blood.V126.23.1205.1205  0.306
2013 Mansour MR, Sanda T, Lawton LN, Li X, Kreslavsky T, Novina CD, Brand M, Gutierrez A, Kelliher MA, Jamieson CH, von Boehmer H, Young RA, Look AT. The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia. The Journal of Experimental Medicine. 210: 1545-57. PMID 23857984 DOI: 10.1084/Jem.20122516  0.486
2013 Joyce CE, Novina CD. miR-155 in acute myeloid leukemia: not merely a prognostic marker? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2219-21. PMID 23650419 DOI: 10.1200/Jco.2012.48.3180  0.482
2013 Horman SR, Janas MM, Litterst C, Wang B, MacRae IJ, Sever MJ, Morrissey DV, Graves P, Luo B, Umesalma S, Qi HH, Miraglia LJ, Novina CD, Orth AP. Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets. Molecular Cell. 50: 356-67. PMID 23603119 DOI: 10.1016/J.Molcel.2013.03.015  0.758
2012 Janas MM, Wang B, Harris AS, Aguiar M, Shaffer JM, Subrahmanyam YV, Behlke MA, Wucherpfennig KW, Gygi SP, Gagnon E, Novina CD. Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins. Rna (New York, N.Y.). 18: 2041-55. PMID 23019594 DOI: 10.1261/Rna.035675.112  0.761
2012 Janas MM, Wang E, Love T, Harris AS, Stevenson K, Semmelmann K, Shaffer JM, Chen PH, Doench JG, Yerramilli SV, Neuberg DS, Iliopoulos D, Housman DE, Burge CB, Novina CD. Reduced expression of ribosomal proteins relieves microRNA-mediated repression. Molecular Cell. 46: 171-86. PMID 22541556 DOI: 10.1016/J.Molcel.2012.04.008  0.769
2012 Janas MM, Novina CD. Not lost in translation: stepwise regulation of microRNA targets. The Embo Journal. 31: 2446-7. PMID 22522704 DOI: 10.1038/Emboj.2012.119  0.772
2012 Mansour MR, Sanda T, Lawton LN, Li X, Kreslavsky T, Novina C, von Boehmer H, Young R, Look AT. The TAL1 Complex Represses the FBXW7 Tumor Suppressor Through Mir-223 in Human T-Cell Acute Lymphoblastic Leukemia Blood. 120: 1296-1296. DOI: 10.1182/Blood.V120.21.1296.1296  0.508
2011 Janas MM, Khaled M, Schubert S, Bernstein JG, Golan D, Veguilla RA, Fisher DE, Shomron N, Levy C, Novina CD. Feed-forward microprocessing and splicing activities at a microRNA-containing intron. Plos Genetics. 7: e1002330. PMID 22028668 DOI: 10.1371/Journal.Pgen.1002330  0.765
2011 Novina CD. New insights into the biology of melanomas using a microRNA tool-KIT. Cell Cycle (Georgetown, Tex.). 10: 2828-9. PMID 21869597 DOI: 10.4161/Cc.10.17.16571  0.339
2011 Li X, Sanda T, Look AT, Novina CD, von Boehmer H. Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL. The Journal of Experimental Medicine. 208: 663-75. PMID 21464222 DOI: 10.1084/Jem.20102384  0.387
2011 Li S, Moffett HF, Lu J, Werner L, Zhang H, Ritz J, Neuberg D, Wucherpfennig KW, Brown JR, Novina CD. MicroRNA expression profiling identifies activated B cell status in chronic lymphocytic leukemia cells. Plos One. 6: e16956. PMID 21408091 DOI: 10.1371/Journal.Pone.0016956  0.46
2010 Levy C, Khaled M, Iliopoulos D, Janas MM, Schubert S, Pinner S, Chen PH, Li S, Fletcher AL, Yokoyama S, Scott KL, Garraway LA, Song JS, Granter SR, Turley SJ, ... ... Novina CD, et al. Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma. Molecular Cell. 40: 841-9. PMID 21109473 DOI: 10.1016/J.Molcel.2010.11.020  0.696
2009 Wang B, Li S, Qi HH, Chowdhury D, Shi Y, Novina CD. Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Nature Structural & Molecular Biology. 16: 1259-66. PMID 19946268 DOI: 10.1038/Nsmb.1712  0.431
2009 Omer AD, Janas MM, Novina CD. The chicken or the egg: microRNA-mediated regulation of mRNA translation or mRNA stability. Molecular Cell. 35: 739-40. PMID 19782024 DOI: 10.1016/J.Molcel.2009.09.003  0.728
2009 Cosmopoulos K, Pegtel M, Hawkins J, Moffett H, Novina C, Middeldorp J, Thorley-Lawson DA. Comprehensive profiling of Epstein-Barr virus microRNAs in nasopharyngeal carcinoma. Journal of Virology. 83: 2357-67. PMID 19091858 DOI: 10.1128/Jvi.02104-08  0.501
2009 Roccaro AM, Sacco A, Chen C, Runnels J, Leleu X, Azab F, Azab AK, Jia X, Ngo HT, Melhem MR, Burwick N, Varticovski L, Novina CD, Rollins BJ, Anderson KC, et al. microRNA expression in the biology, prognosis, and therapy of Waldenström macroglobulinemia. Blood. 113: 4391-402. PMID 19074725 DOI: 10.1182/Blood-2008-09-178228  0.54
2009 Roccaro A, Jia X, Ngo H, Melhem, Sacco A, Chen C, Leleu X, Runnels J, Azab F, Azab A, Quang P, Varticovski L, Novina C, Rollins B, Anderson K, et al. B354 MicroRNA Expression in the Biology, Prognosis, and Therapy of Waldenström Macroglobulinemia Clinical Lymphoma, Myeloma & Leukemia. 9: 0-0. DOI: 10.1016/S1557-9190(11)70713-2  0.537
2008 Wang B, Yanez A, Novina CD. MicroRNA-repressed mRNAs contain 40S but not 60S components. Proceedings of the National Academy of Sciences of the United States of America. 105: 5343-8. PMID 18390669 DOI: 10.1073/Pnas.0801102105  0.573
2008 Love TM, Moffett HF, Novina CD. Not miR-ly small RNAs: big potential for microRNAs in therapy. The Journal of Allergy and Clinical Immunology. 121: 309-19. PMID 18269923 DOI: 10.1016/J.Jaci.2007.12.1167  0.553
2008 Novina CD, Chabner BA. RNA-Directed Therapy: The Next Step in the miRNA Revolution. The Oncologist. 13: 1-3. PMID 18245006 DOI: 10.1634/Theoncologist.2007-0236  0.573
2008 Roccaro AM, Sacco A, Chen C, Leleu X, Runnels J, Azab F, Azab AK, Jia X, Ngo HT, Melhem MR, Burwick N, Quang P, Varticovski L, Novina CD, Rollins BJ, et al. MicroRNA Signature in Waldenstrom Macroglobulinemia Blood. 112: 630-630. DOI: 10.1182/Blood.V112.11.630.630  0.556
2007 Wang B, Doench JG, Novina CD. Analysis of microRNA effector functions in vitro. Methods (San Diego, Calif.). 43: 91-104. PMID 17889795 DOI: 10.1016/J.Ymeth.2007.04.003  0.386
2007 Moffett HF, Novina CD. A small RNA makes a Bic difference. Genome Biology. 8: 221. PMID 17666120 DOI: 10.1186/Gb-2007-8-7-221  0.428
2006 Wang B, Love TM, Call ME, Doench JG, Novina CD. Recapitulation of short RNA-directed translational gene silencing in vitro. Molecular Cell. 22: 553-60. PMID 16713585 DOI: 10.1016/J.Molcel.2006.03.034  0.576
2005 Chowdhury D, Novina CD. RNAi and RNA-based regulation of immune system function. Advances in Immunology. 88: 267-92. PMID 16227093 DOI: 10.1016/S0065-2776(05)88008-3  0.393
2005 Chowdhury D, Novina CD. Potential roles for short RNAs in lymphocytes. Immunology and Cell Biology. 83: 201-10. PMID 15877596 DOI: 10.1111/J.1440-1711.2005.01333.X  0.351
2003 Song E, Lee SK, Dykxhoorn DM, Novina C, Zhang D, Crawford K, Cerny J, Sharp PA, Lieberman J, Manjunath N, Shankar P. Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages. Journal of Virology. 77: 7174-81. PMID 12805416 DOI: 10.1128/Jvi.77.13.7174-7181.2003  0.304
2003 Dykxhoorn DM, Novina CD, Sharp PA. Killing the messenger: short RNAs that silence gene expression. Nature Reviews. Molecular Cell Biology. 4: 457-67. PMID 12778125 DOI: 10.1038/Nrm1129  0.349
2003 Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, Sabatini DM, Chen IS, Hahn WC, Sharp PA, Weinberg RA, Novina CD. Lentivirus-delivered stable gene silencing by RNAi in primary cells. Rna (New York, N.Y.). 9: 493-501. PMID 12649500 DOI: 10.1261/Rna.2192803  0.346
2002 Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman RG, Lieberman J, Shankar P, Sharp PA. siRNA-directed inhibition of HIV-1 infection. Nature Medicine. 8: 681-6. PMID 12042777 DOI: 10.1038/Nm725  0.321
2000 Morikawa N, Clarke TR, Novina CD, Watanabe K, Haqq C, Weiss M, Roy AL, Donahoe PK. Human mullerian-inhibiting substance promoter contains a functional TFII-I-binding initiator Biology of Reproduction. 63: 1075-1083. PMID 10993829 DOI: 10.1095/Biolreprod63.4.1075  0.325
1998 Novina CD, Cheriyath V, Roy AL. Regulation of TFII-I activity by phosphorylation Journal of Biological Chemistry. 273: 33443-33448. PMID 9837922 DOI: 10.1074/Jbc.273.50.33443  0.308
1998 Cheriyath V, Novina CD, Roy AL. TFII-I regulates Vβ promoter activity through an initiator element Molecular and Cellular Biology. 18: 4444-4454. PMID 9671454 DOI: 10.1128/Mcb.18.8.4444  0.306
1997 Novina CD, Cheriyath V, Denis MC, Roy AL. Methods for studying the biochemical properties of an Inr element binding protein: TFII-I Methods: a Companion to Methods in Enzymology. 12: 254-263. PMID 9237169 DOI: 10.1006/Meth.1997.0477  0.329
1996 Novina CD, Roy AL. Core promoters and transcriptional control Trends in Genetics. 12: 351-355. DOI: 10.1016/S0168-9525(96)80017-5  0.325
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