Mauricio J. Reginato - Publications

Affiliations: 
2004- Biochemistry & Molecular Biology Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
Cell Biology, Oncology
Website:
https://drexel.edu/medicine/faculty/profiles/mauricio-reginato/

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Ciraku L, Bacigalupa ZA, Ju J, Moeller RA, Le Minh G, Lee RH, Smith MD, Ferrer CM, Trefely S, Izzo LT, Doan MT, Gocal WA, D'Agostino L, Shi W, Jackson JG, ... ... Reginato MJ, et al. O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation. Oncogene. PMID 35190642 DOI: 10.1038/s41388-022-02237-6  0.828
2021 Ciraku L, Esquea EM, Reginato MJ. O-GlcNAcylation regulation of cellular signaling in cancer. Cellular Signalling. 110201. PMID 34800629 DOI: 10.1016/j.cellsig.2021.110201  0.466
2021 Ciraku L, Moeller RA, Esquea EM, Gocal WA, Hartsough EJ, Simone NL, Jackson JG, Reginato MJ. An Ex Vivo Brain Slice Model to Study and Target Breast Cancer Brain Metastatic Tumor Growth. Journal of Visualized Experiments : Jove. PMID 34633392 DOI: 10.3791/62617  0.302
2020 Akella NM, Le Minh G, Ciraku L, Mukherjee A, Bacigalupa ZA, Mukhopadhyay D, Sodi VL, Reginato MJ. O-GlcNAc Transferase Regulates Cancer Stem-like Potential of Breast Cancer Cells. Molecular Cancer Research : McR. PMID 31974291 DOI: 10.1158/1541-7786.Mcr-19-0732  0.816
2019 Akella NM, Ciraku L, Reginato MJ. Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer. Bmc Biology. 17: 52. PMID 31272438 DOI: 10.1186/S12915-019-0671-3  0.822
2019 Delaney LJ, Ciraku L, Oeffinger BE, Wessner CE, Liu JB, Li J, Nam K, Forsberg F, Leeper DB, O'Kane P, Wheatley MA, Reginato MJ, Eisenbrey JR. Breast Cancer Brain Metastasis Response to Radiation After Microbubble Oxygen Delivery in a Murine Model. Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. PMID 31124171 DOI: 10.1002/Jum.15031  0.469
2018 Bacigalupa ZA, Bhadiadra CH, Reginato MJ. O-GlcNAcylation: key regulator of glycolytic pathways. Journal of Bioenergetics and Biomembranes. PMID 29344764 DOI: 10.1007/S10863-018-9742-3  0.857
2017 Sodi VL, Bacigalupa ZA, Ferrer CM, Lee JV, Gocal WA, Mukhopadhyay D, Wellen KE, Ivan M, Reginato MJ. Nutrient sensor O-GlcNAc transferase controls cancer lipid metabolism via SREBP-1 regulation. Oncogene. PMID 29059153 DOI: 10.1038/Onc.2017.395  0.824
2017 Beatty A, Fink LS, Singh T, Strigun A, Peter E, Ferrer CM, Nicolas E, Cai KQ, Moran TP, Reginato MJ, Rennefahrt U, Peterson JR. Metabolite profiling reveals the glutathione biosynthetic pathway as a therapeutic target in triple negative breast cancer. Molecular Cancer Therapeutics. PMID 29021292 DOI: 10.1158/1535-7163.Mct-17-0407  0.833
2017 Segovia-Mendoza M, Díaz L, Prado-Garcia H, Reginato MJ, Larrea F, García-Becerra R. The addition of calcitriol or its synthetic analog EB1089 to lapatinib and neratinib treatment inhibits cell growth and promotes apoptosis in breast cancer cells. American Journal of Cancer Research. 7: 1486-1500. PMID 28744399  0.461
2016 Li C, Li N, Liu X, Zhang EY, Sun Y, Masuda K, Li J, Sun J, Morrison T, Li X, Chen Y, Wang J, Karim NA, Zhang Y, Blenis J, ... Reginato MJ, et al. Proapoptotic protein Bim attenuates estrogen-enhanced survival in lymphangioleiomyomatosis. Jci Insight. 1: e86629. PMID 27882343 DOI: 10.1172/Jci.Insight.86629  0.384
2016 Ferrer CM, Lu TY, Bacigalupa ZA, Katsetos CD, Sinclair DA, Reginato MJ. O-GlcNAcylation regulates breast cancer metastasis via SIRT1 modulation of FOXM1 pathway. Oncogene. PMID 27345396 DOI: 10.1038/Onc.2016.228  0.856
2016 Ferrer CM, Sodi VL, Reginato MJ. O-GlcNAcylation in Cancer Biology: Linking Metabolism and Signaling. Journal of Molecular Biology. PMID 27343361 DOI: 10.1016/J.Jmb.2016.05.028  0.844
2015 Ferrer CM, Reginato MJ. Sweet connections: O-GlcNAcylation links cancer cell metabolism and survival. Molecular & Cellular Oncology. 2: e961809. PMID 27308381 DOI: 10.4161/23723548.2014.961809  0.845
2015 Karakashev SV, Reginato MJ. Progress toward overcoming hypoxia-induced resistance to solid tumor therapy. Cancer Management and Research. 7: 253-64. PMID 26316817 DOI: 10.2147/Cmar.S58285  0.823
2015 Katsetos CD, Reginato MJ, Baas PW, D'Agostino L, Legido A, Tuszyn Ski JA, Dráberová E, Dráber P. Emerging microtubule targets in glioma therapy. Seminars in Pediatric Neurology. 22: 49-72. PMID 25976261 DOI: 10.1016/J.Spen.2015.03.009  0.384
2015 Sodi VL, Khaku S, Krutilina R, Schwab LP, Vocadlo DJ, Seagroves TN, Reginato MJ. mTOR/MYC Axis Regulates O-GlcNAc Transferase Expression and O-GlcNAcylation in Breast Cancer. Molecular Cancer Research : McR. 13: 923-33. PMID 25636967 DOI: 10.1158/1541-7786.Mcr-14-0536  0.86
2015 Karakashev SV, Reginato MJ. Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2. Oncotarget. 6: 1967-80. PMID 25596742 DOI: 10.18632/Oncotarget.2806  0.835
2015 Tchafa AM, Ta M, Reginato MJ, Shieh AC. EMT Transition Alters Interstitial Fluid Flow-Induced Signaling in ERBB2-Positive Breast Cancer Cells. Molecular Cancer Research : McR. 13: 755-64. PMID 25566992 DOI: 10.1158/1541-7786.Mcr-14-0471  0.532
2015 Karakashev S, Reginato M. Abstract 716: Targeting Mek-Erk pathway abrogates hypoxia-mediated lapatinib resistance in ErbB2-positive breast cancer cells Cancer Research. 75: 716-716. DOI: 10.1158/1538-7445.Am2015-716  0.833
2015 Sodi VL, Bacigalupa Z, Ferrer C, Reginato M. Abstract 1194: O-GlcNAcylation regulates breast cancer lipid metabolism via sterol regulatory element binding protein 1 Cancer Research. 75: 1194-1194. DOI: 10.1158/1538-7445.Am2015-1194  0.836
2014 Ferrer CM, Reginato MJ. Cancer metabolism: cross talk between signaling and O-GlcNAcylation. Methods in Molecular Biology (Clifton, N.J.). 1176: 73-88. PMID 25030920 DOI: 10.1007/978-1-4939-0992-6_7  0.838
2014 Ferrer CM, Lynch TP, Sodi VL, Falcone JN, Schwab LP, Peacock DL, Vocadlo DJ, Seagroves TN, Reginato MJ. O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway. Molecular Cell. 54: 820-31. PMID 24857547 DOI: 10.1016/J.Molcel.2014.04.026  0.838
2014 Ferrer CM, Reginato MJ. Sticking to sugars at the metastatic site: sialyltransferase ST6GalNAc2 acts as a breast cancer metastasis suppressor. Cancer Discovery. 4: 275-7. PMID 24596201 DOI: 10.1158/2159-8290.Cd-14-0075  0.837
2014 Martín-Pérez R, Palacios C, Yerbes R, Cano-González A, Iglesias-Serret D, Gil J, Reginato MJ, López-Rivas A. Activated ERBB2/HER2 licenses sensitivity to apoptosis upon endoplasmic reticulum stress through a PERK-dependent pathway. Cancer Research. 74: 1766-77. PMID 24453000 DOI: 10.1158/0008-5472.Can-13-1747  0.461
2014 Kambach DM, Sodi VL, Lelkes PI, Azizkhan-Clifford J, Reginato MJ. ErbB2, FoxM1 and 14-3-3ζ prime breast cancer cells for invasion in response to ionizing radiation. Oncogene. 33: 589-98. PMID 23318431 DOI: 10.1038/Onc.2012.629  0.819
2013 Ferdin J, Nishida N, Wu X, Nicoloso MS, Shah MY, Devlin C, Ling H, Shimizu M, Kumar K, Cortez MA, Ferracin M, Bi Y, Yang D, Czerniak B, Zhang W, ... ... Reginato MJ, et al. HINCUTs in cancer: hypoxia-induced noncoding ultraconserved transcripts. Cell Death and Differentiation. 20: 1675-87. PMID 24037088 DOI: 10.1038/Cdd.2013.119  0.447
2013 Whelan KA, Schwab LP, Karakashev SV, Franchetti L, Johannes GJ, Seagroves TN, Reginato MJ. The oncogene HER2/neu (ERBB2) requires the hypoxia-inducible factor HIF-1 for mammary tumor growth and anoikis resistance. The Journal of Biological Chemistry. 288: 15865-77. PMID 23585570 DOI: 10.1074/Jbc.M112.426999  0.834
2013 Botta GP, Reichert M, Reginato MJ, Heeg S, Rustgi AK, Lelkes PI. ERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells. Neoplasia (New York, N.Y.). 15: 359-72. PMID 23555182 DOI: 10.1593/Neo.121708  0.33
2012 Yerbes R, López-Rivas A, Reginato MJ, Palacios C. Control of FLIP L expression and TRAIL resistance by the extracellular signal-regulated kinase1/2 pathway in breast epithelial cells Cell Death & Differentiation. 19: 1908-1916. PMID 22722337 DOI: 10.1038/Cdd.2012.78  0.487
2012 Lynch TP, Ferrer CM, Jackson SR, Shahriari KS, Vosseller K, Reginato MJ. Critical role of O-Linked β-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis. The Journal of Biological Chemistry. 287: 11070-81. PMID 22275356 DOI: 10.1074/Jbc.M111.302547  0.858
2012 Botta GP, Reginato MJ, Reichert M, Rustgi AK, Lelkes PI. Constitutive K-RasG12D activation of ERK2 specifically regulates 3D invasion of human pancreatic cancer cells via MMP-1. Molecular Cancer Research : McR. 10: 183-96. PMID 22160930 DOI: 10.1158/1541-7786.Mcr-11-0399  0.355
2012 Kambach DM, Sodi V, Lelkes PI, Reginato M, Azizkhan-Clifford J. Abstract LB-212: Ionizing radiation selectively promotes invasion of ErbB2-expressing breast cancer cells via regulation of FoxM1 Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-212  0.818
2012 Qie S, Chu C, Li W, Wang C, Reginato M, Sang N. Abstract 5143: ErbB2 activation up-regulates glutaminase 1 expression via NF-κB pathway Cancer Research. 72: 5143-5143. DOI: 10.1158/1538-7445.Am2012-5143  0.584
2011 Whelan KA, Reginato MJ. Surviving without oxygen: Hypoxia regulation of mammary morphogenesis and anoikis Cell Cycle. 10: 2287-2294. PMID 21670595 DOI: 10.4161/Cc.10.14.16532  0.74
2011 Lynch TP, Reginato MJ. O-GlcNAc transferase: a sweet new cancer target. Cell Cycle (Georgetown, Tex.). 10: 1712-3. PMID 21519190 DOI: 10.4161/Cc.10.11.15561  0.732
2011 Yerbes R, Palacios C, Reginato MJ, López-Rivas A. Cellular FLIP(L) plays a survival role and regulates morphogenesis in breast epithelial cells. Biochimica Et Biophysica Acta. 1813: 168-78. PMID 20951169 DOI: 10.1016/J.Bbamcr.2010.10.003  0.453
2011 Lynch TP, Jackson SR, Shahriari KS, Ferrer CM, Lazarus M, Walker S, Vosseller K, Reginato MJ. Abstract 1267: Metabolic sensor O-GlcNAc Transferase is a novel regulator of prostate cancer invasion and angiogenesis via regulation of FoxM1 Cancer Research. 71: 1267-1267. DOI: 10.1158/1538-7445.Am2011-1267  0.846
2010 Whelan KA, Caldwell SA, Shahriari KS, Jackson SR, Franchetti LD, Johannes GJ, Reginato MJ. Hypoxia suppression of Bim and Bmf blocks anoikis and luminal clearing during mammary morphogenesis. Molecular Biology of the Cell. 21: 3829-37. PMID 20861305 DOI: 10.1091/Mbc.E10-04-0353  0.744
2010 Haenssen KK, Caldwell SA, Shahriari KS, Jackson SR, Whelan KA, Klein-Szanto AJ, Reginato MJ. ErbB2 requires integrin alpha5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells. Journal of Cell Science. 123: 1373-82. PMID 20332114 DOI: 10.1242/Jcs.050906  0.785
2010 Caldwell SA, Jackson SR, Shahriari KS, Lynch TP, Sethi G, Walker S, Vosseller K, Reginato MJ. Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1. Oncogene. 29: 2831-42. PMID 20190804 DOI: 10.1038/Onc.2010.41  0.814
2008 Sodunke T, Reginato M, Noh H“. Micropatterned matrigel track for 3D single breast cancer cell metastasis Journal of Biotechnology. 136. DOI: 10.1016/J.Jbiotec.2008.07.250  0.487
2007 Sodunke TR, Turner KK, Caldwell SA, McBride KW, Reginato MJ, Noh HM. Micropatterns of Matrigel for three-dimensional epithelial cultures. Biomaterials. 28: 4006-16. PMID 17574663 DOI: 10.1016/J.Biomaterials.2007.05.021  0.371
2006 Reginato MJ, Muthuswamy SK. Illuminating the center: mechanisms regulating lumen formation and maintenance in mammary morphogenesis. Journal of Mammary Gland Biology and Neoplasia. 11: 205-11. PMID 17115263 DOI: 10.1007/S10911-006-9030-4  0.404
2005 Yan SR, Joseph RR, Rosen K, Reginato MJ, Jackson A, Allaire N, Brugge JS, Jobin C, Stadnyk AW. Activation of NF-kappaB following detachment delays apoptosis in intestinal epithelial cells. Oncogene. 24: 6482-91. PMID 16007176 DOI: 10.1038/Sj.Onc.1208810  0.577
2005 Reginato MJ, Mills KR, Becker EB, Lynch DK, Bonni A, Muthuswamy SK, Brugge JS. Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes. Molecular and Cellular Biology. 25: 4591-601. PMID 15899862 DOI: 10.1128/Mcb.25.11.4591-4601.2005  0.723
2004 Martin SS, Ridgeway AG, Pinkas J, Lu Y, Reginato MJ, Koh EY, Michelman M, Daley GQ, Brugge JS, Leder P. A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth. Oncogene. 23: 4641-5. PMID 15064711 DOI: 10.1038/Sj.Onc.1207595  0.63
2004 Mills KR, Reginato M, Debnath J, Queenan B, Brugge JS. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro. Proceedings of the National Academy of Sciences of the United States of America. 101: 3438-43. PMID 14993595 DOI: 10.1073/Pnas.0400443101  0.698
2003 Reginato MJ, Mills KR, Paulus JK, Lynch DK, Sgroi DC, Debnath J, Muthuswamy SK, Brugge JS. Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nature Cell Biology. 5: 733-40. PMID 12844146 DOI: 10.1038/Ncb1026  0.734
2002 Debnath J, Mills KR, Collins NL, Reginato MJ, Muthuswamy SK, Brugge JS. The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell. 111: 29-40. PMID 12372298 DOI: 10.1016/S0092-8674(02)01001-2  0.785
1999 Reginato MJ, Lazar MA. Mechanisms by which thiazolidinediones enhance insulin action Trends in Endocrinology and Metabolism. 10: 9-13. DOI: 10.1016/S1043-2760(98)00110-6  0.484
1998 Shao D, Rangwala SM, Bailey ST, Krakow SL, Reginato MJ, Lazar MA. Interdomain communication regulating ligand binding by PPAR-γ Nature. 396: 377-380. PMID 9845075 DOI: 10.1038/24634  0.518
1998 Reginato MJ, Bailey ST, Krakow SL, Minami C, Ishii S, Tanaka H, Lazar MA. A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor γ-activating properties Journal of Biological Chemistry. 273: 32679-32684. PMID 9830009 DOI: 10.1074/Jbc.273.49.32679  0.499
1998 Reginato MJ, Krakow SL, Bailey ST, Lazar MA. Prostaglandins promote and block adipogenesis through opposing effects on peroxisome proliferator-activated receptor γ Journal of Biological Chemistry. 273: 1855-1858. PMID 9442016 DOI: 10.1074/Jbc.273.4.1855  0.545
1997 Schwarz EJ, Reginato MJ, Shao D, Krakow SL, Lazar MA. Retinoic acid blocks adipogenesis by inhibiting C/EBPβ-mediated transcription Molecular and Cellular Biology. 17: 1552-1561. PMID 9032283 DOI: 10.1128/Mcb.17.3.1552  0.491
1997 Cheng X, Reginato MJ, Andrews NC, Lazar MA. The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2 Molecular and Cellular Biology. 17: 1407-1416. PMID 9032267 DOI: 10.1128/Mcb.17.3.1407  0.499
1997 Adams M, Reginato MJ, Shao D, Lazar MA, Chatterjee VK. Transcriptional activation by peroxisome proliferator-activated receptor γ is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site Journal of Biological Chemistry. 272: 5128-5132. PMID 9030579 DOI: 10.1074/Jbc.272.8.5128  0.545
1996 Reginato MJ, Zhang J, Lazar MA. DNA-independent and DNA-dependent mechanisms regulate the differential heterodimerization of the isoforms of the thyroid hormone receptor with retinoid X receptor Journal of Biological Chemistry. 271: 28199-28205. PMID 8910436 DOI: 10.1074/Jbc.271.45.28199  0.473
1995 Katz D, Reginato MJ, Lazar MA. Functional regulation of thyroid hormone receptor variant TRα2 by phosphorylation Molecular and Cellular Biology. 15: 2341-2348. PMID 7739517 DOI: 10.1128/Mcb.15.5.2341  0.512
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