Marja M. Hurley - Publications

Affiliations: 
University of Connecticut, Storrs, CT, United States 
Area:
Cell Biology, Endocrinology Biology, Aging

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kuhn LT, Peng T, Gronowicz G, Hurley MM. Endogenous FGF-2 levels impact FGF-2/BMP-2 growth factor delivery dosing in aged murine calvarial bone defects. Journal of Biomedical Materials Research. Part A. PMID 34173706 DOI: 10.1002/jbm.a.37249  0.48
2021 Homer-Bouthiette C, Xiao L, Hurley MM. Gait disturbances and muscle dysfunction in fibroblast growth factor 2 knockout mice. Scientific Reports. 11: 11005. PMID 34040128 DOI: 10.1038/s41598-021-90565-0  0.72
2020 Xiao L, Williams D, Hurley MM. Inhibition of FGFR Signaling Partially Rescues Osteoarthritis in Mice Overexpressing High Molecular Weight FGF2 Isoforms. Endocrinology. 161. PMID 31901095 DOI: 10.1210/Endocr/Bqz016  0.72
2018 Xiao L, Fei Y, Hurley MM. FGF2 crosstalk with Wnt signaling in mediating the anabolic action of PTH on bone formation. Bone Reports. 9: 136-144. PMID 30258857 DOI: 10.1016/J.Bonr.2018.09.003  1
2018 Alhamdi J, Jacobs E, Gronowicz G, Benkirane-Jessel N, Hurley M, Kuhn L. Cell Type Influences Local Delivery of Biomolecules from a Bioinspired Apatite Drug Delivery System. Materials (Basel, Switzerland). 11. PMID 30217000 DOI: 10.3390/Ma11091703  0.48
2018 Burt PM, Xiao L, Doetschman T, Hurley MM. Ablation of low-molecular-weight FGF2 isoform accelerates murine osteoarthritis while loss of high-molecular-weight FGF2 isoforms offers protection. Journal of Cellular Physiology. PMID 30144364 DOI: 10.1002/Jcp.27230  0.72
2018 Meo Burt P, Xiao L, Hurley MM. FGF23 regulates Wnt/β-catenin signaling-mediated osteoarthritis in mice overexpressing high molecular weight FGF2. Endocrinology. PMID 29718273 DOI: 10.1210/En.2018-00184  0.72
2018 Xiao L, Homer-Bouthiette C, Hurley MM. FGF23 Neutralizing Antibody Partially Improves Bone Mineralization Defect of HMWFGF2 Isoforms Transgenic Female Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29502359 DOI: 10.1002/Jbmr.3417  0.72
2017 Gronowicz G, Jacobs E, Peng T, Zhu L, Hurley M, Kuhn LT. Calvarial bone regeneration is enhanced by sequential delivery of FGF-2 and BMP-2 from layer-by-layer coatings with a biomimetic calcium phosphate barrier layer. Tissue Engineering. Part A. PMID 28946792 DOI: 10.1089/ten.TEA.2017.0111  0.48
2017 Xiao L, Du E, Homer-Bouthiette C, Hurley MM. Inhibition of FGFR Signaling Partially Rescues Hypophosphatemic Rickets in HMWFGF2 Tg Male Mice. Endocrinology. PMID 28938491 DOI: 10.1210/En.2016-1617  0.72
2016 Jacobs E, Gronowicz G, Hurley M, Kuhn LT. Biomimetic Calcium Phosphate/Polyelectrolyte Multilayer Coatings for Sequential Delivery of Multiple Biological Factors. Journal of Biomedical Materials Research. Part A. PMID 28002652 DOI: 10.1002/Jbm.A.35985  0.48
2016 Burt PM, Xiao L, Dealy C, Fisher MC, Hurley MM. FGF2 High Molecular Weight Isoforms Contribute to Osteoarthropathy in Male Mice. Endocrinology. en20161548. PMID 27732085 DOI: 10.1210/En.2016-1548  0.72
2016 Du E, Xiao L, Hurley MM. FGF23 Neutralizing Antibody Ameliorates Hypophosphatemia and Impaired FGF Receptor Signaling in Kidneys of HMWFGF2 Transgenic Mice. Journal of Cellular Physiology. PMID 27306296 DOI: 10.1002/Jcp.25458  1
2016 Xiao L, Andemariam B, Taxel P, Adams DJ, Zempsky WT, Hurley MM. Loss of Bone in Sickle Cell Trait and Sickle Cell Disease Female Mice Is Associated with Reduced IGF-1 in Bone and Serum. Endocrinology. en20152001. PMID 27171384 DOI: 10.1210/En.2015-2001  0.72
2016 Du E, Xiao L, Hurley MM. FGFR Inhibitor Ameliorates Hypophosphatemia and Impaired Engrailed-1/Wnt Signaling in FGF2 High Molecular Weight Isoform Transgenic Mice. Journal of Cellular Biochemistry. PMID 26762209 DOI: 10.1002/Jcb.25493  0.72
2015 Hurley MM, Gronowicz G, Zhu L, Kuhn LT, Rodner C, Xiao L. Age-Related Changes in FGF-2, Fibroblast Growth Factor Receptors and β-Catenin Expression in Human Mesenchyme-Derived Progenitor Cells. Journal of Cellular Biochemistry. PMID 26332075 DOI: 10.1002/Jcb.25357  1
2015 Hurley MM, Adams DJ, Wang L, Jiang X, Meo Burt P, Du E, Xiao L. Accelerated Fracture Healing in Transgenic Mice Overexpressing an Anabolic Isoform of Fibroblast Growth Factor 2. Journal of Cellular Biochemistry. PMID 26252425 DOI: 10.1002/Jcb.25308  1
2015 Charles LF, Woodman JL, Ueno D, Gronowicz G, Hurley MM, Kuhn LT. Effects of low dose FGF-2 and BMP-2 on healing of calvarial defects in old mice. Experimental Gerontology. 64: 62-9. PMID 25681640 DOI: 10.1016/J.Exger.2015.02.006  1
2014 Homer-Bouthiette C, Doetschman T, Xiao L, Hurley MM. Knockout of nuclear high molecular weight FGF2 isoforms in mice modulates bone and phosphate homeostasis. The Journal of Biological Chemistry. 289: 36303-14. PMID 25389287 DOI: 10.1074/Jbc.M114.619569  0.72
2014 Gronowicz G, Hurley MM, Kuhn LT. Optimizing BMP-2-induced bone repair with FGF-2. The Journal of the American Academy of Orthopaedic Surgeons. 22: 677-9. PMID 25281263 DOI: 10.5435/Jaaos-22-10-677  0.48
2014 Xiao L, Ueno D, Catros S, Homer-Bouthiette C, Charles L, Kuhn L, Hurley MM. Fibroblast growth factor-2 isoform (low molecular weight/18 kDa) overexpression in preosteoblast cells promotes bone regeneration in critical size calvarial defects in male mice. Endocrinology. 155: 965-74. PMID 24424065 DOI: 10.1210/En.2013-1919  1
2014 Gronowicz G, Hurley MM, Kuhn LT. Optimizing BMP-2-induced bone repair with FGF-2 Journal of the American Academy of Orthopaedic Surgeons. 22: 677-679. DOI: 10.5435/JAAOS-22-10-677  1
2014 Homer-Bouthiette C, Doetschman T, Xiao L, Hurley MM. Knockout of nuclear high molecular weight FGF2 isoforms in mice modulates bone and phosphate homeostasis Journal of Biological Chemistry. 289: 36303-36314. DOI: 10.1074/jbc.M114.619569  1
2013 Sabbieti MG, Agas D, Marchetti L, Coffin JD, Xiao L, Hurley MM. BMP-2 differentially modulates FGF-2 isoform effects in osteoblasts from newborn transgenic mice. Endocrinology. 154: 2723-33. PMID 23715864 DOI: 10.1210/En.2013-1025  1
2013 Agas D, Sabbieti MG, Marchetti L, Xiao L, Hurley MM. FGF-2 enhances Runx-2/Smads nuclear localization in BMP-2 canonical signaling in osteoblasts Journal of Cellular Physiology. 228: 2149-2158. PMID 23559326 DOI: 10.1002/Jcp.24382  1
2013 Kuhn LT, Ou G, Charles L, Hurley MM, Rodner CM, Gronowicz G. Fibroblast growth factor-2 and bone morphogenetic protein-2 have a synergistic stimulatory effect on bone formation in cell cultures from elderly mouse and human bone. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 1170-80. PMID 23531867 DOI: 10.1093/Gerona/Glt018  1
2013 Fei Y, Gronowicz G, Hurley MM. Fibroblast growth factor-2, bone homeostasis and fracture repair Current Pharmaceutical Design. 19: 3354-3363. PMID 23432676 DOI: 10.2174/1381612811319190002  1
2013 Xiao L, Esliger A, Hurley MM. Nuclear fibroblast growth factor 2 (FGF2) isoforms inhibit bone marrow stromal cell mineralization through FGF23/FGFR/MAPK in vitro. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 35-45. PMID 22836867 DOI: 10.1002/Jbmr.1721  1
2013 Agas D, Marchetti L, Hurley MM, Sabbieti MG. Prostaglandin F2α: a bone remodeling mediator. Journal of Cellular Physiology. 228: 25-9. PMID 22585670 DOI: 10.1002/Jcp.24117  1
2012 Fei Y, Xu RH, Hurley MM. Stem cell-based bone repair. American Journal of Stem Cells. 1: 106-13. PMID 23671803  1
2012 Fei Y, Hurley MM. Role of fibroblast growth factor 2 and Wnt signaling in anabolic effects of parathyroid hormone on bone formation. Journal of Cellular Physiology. 227: 3539-45. PMID 22378151 DOI: 10.1002/Jcp.24075  1
2011 Fei Y, Xiao L, Doetschman T, Coffin DJ, Hurley MM. Fibroblast growth factor 2 stimulation of osteoblast differentiation and bone formation is mediated by modulation of the Wnt signaling pathway. The Journal of Biological Chemistry. 286: 40575-83. PMID 21987573 DOI: 10.1074/Jbc.M111.274910  1
2011 Fei Y, Xiao L, Hurley MM. The impaired bone anabolic effect of PTH in the absence of endogenous FGF2 is partially due to reduced ATF4 expression. Biochemical and Biophysical Research Communications. 412: 160-4. PMID 21806973 DOI: 10.1016/J.Bbrc.2011.07.066  1
2011 Bilezikian JP, Drezner M, Kream B, Stern P, Clemens T, Elderkin A, Siris E, Krane S, Eisman J, Arnold A, Feyen J, Hurley M, Kawaguchi H, Lorenzo J, Peck W, et al. Lawrence G. Raisz November 13, 1925-August 25, 2010. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 903-11. PMID 21541991 DOI: 10.1002/Jbmr.368  1
2010 Ou G, Charles L, Matton S, Rodner C, Hurley M, Kuhn L, Gronowicz G. Fibroblast growth factor-2 stimulates the proliferation of mesenchyme-derived progenitor cells from aging mouse and human bone. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 65: 1051-9. PMID 20643704 DOI: 10.1093/Gerona/Glq114  0.48
2010 Xiao L, Sobue T, Esliger A, Kronenberg MS, Coffin JD, Doetschman T, Hurley MM. Disruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells. Bone. 47: 360-70. PMID 20510392 DOI: 10.1016/J.Bone.2010.05.021  1
2010 Sabbieti MG, Agas D, Marchetti L, Santoni G, Amantini C, Xiao L, Menghi G, Hurley MM. Signaling pathways implicated in PGF2alpha effects on Fgf2+/+ and Fgf2-/- osteoblasts. Journal of Cellular Physiology. 224: 465-74. PMID 20432442 DOI: 10.1002/Jcp.22143  1
2010 Xiao L, Naganawa T, Lorenzo J, Carpenter TO, Coffin JD, Hurley MM. Nuclear isoforms of fibroblast growth factor 2 are novel inducers of hypophosphatemia via modulation of FGF23 and KLOTHO. The Journal of Biological Chemistry. 285: 2834-46. PMID 19933269 DOI: 10.1074/Jbc.M109.030577  1
2010 Fei Y, Xiao L, Hurley MM. Fibroblast growth factor 2 positively regulates expression of activating transcription factor 4 in osteoblasts. Biochemical and Biophysical Research Communications. 391: 335-9. PMID 19913500 DOI: 10.1016/J.Bbrc.2009.11.059  1
2009 Sabbieti MG, Agas D, Xiao L, Marchetti L, Coffin JD, Doetschman T, Hurley MM. Endogenous FGF-2 is critically important in PTH anabolic effects on bone. Journal of Cellular Physiology. 219: 143-51. PMID 19107841 DOI: 10.1002/Jcp.21661  1
2009 Xiao L, Liu P, Li X, Doetschman T, Coffin JD, Drissi H, Hurley MM. Exported 18-kDa isoform of fibroblast growth factor-2 is a critical determinant of bone mass in mice. The Journal of Biological Chemistry. 284: 3170-82. PMID 19056741 DOI: 10.1074/Jbc.M804900200  1
2008 Naganawa T, Xiao L, Coffin JD, Doetschman T, Sabbieti MG, Agas D, Hurley MM. Reduced expression and function of bone morphogenetic protein-2 in bones of Fgf2 null mice. Journal of Cellular Biochemistry. 103: 1975-88. PMID 17955502 DOI: 10.1002/Jcb.21589  0.72
2006 Hurley MM, Okada Y, Xiao L, Tanaka Y, Ito M, Okimoto N, Nakamura T, Rosen CJ, Doetschman T, Coffin JD. Impaired bone anabolic response to parathyroid hormone in Fgf2-/- and Fgf2+/- mice. Biochemical and Biophysical Research Communications. 341: 989-94. PMID 16455048 DOI: 10.1016/J.Bbrc.2006.01.044  0.72
2006 Naganawa T, Xiao L, Abogunde E, Sobue T, Kalajzic I, Sabbieti M, Agas D, Hurley MM. In vivo and in vitro comparison of the effects of FGF-2 null and haplo-insufficiency on bone formation in mice. Biochemical and Biophysical Research Communications. 339: 490-8. PMID 16298332 DOI: 10.1016/J.Bbrc.2005.10.215  0.72
2005 Li X, Liu P, Liu W, Maye P, Zhang J, Zhang Y, Hurley M, Guo C, Boskey A, Sun L, Harris SE, Rowe DW, Ke HZ, Wu D. Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation. Nature Genetics. 37: 945-52. PMID 16056226 DOI: 10.1038/Ng1614  1
2005 Sobue T, Naganawa T, Xiao L, Okada Y, Tanaka Y, Ito M, Okimoto N, Nakamura T, Coffin JD, Hurley MM. Over-expression of fibroblast growth factor-2 causes defective bone mineralization and osteopenia in transgenic mice. Journal of Cellular Biochemistry. 95: 83-94. PMID 15723277 DOI: 10.1002/Jcb.20389  0.72
2004 Xiao L, Naganawa T, Obugunde E, Gronowicz G, Ornitz DM, Coffin JD, Hurley MM. Stat1 controls postnatal bone formation by regulating fibroblast growth factor signaling in osteoblasts. The Journal of Biological Chemistry. 279: 27743-52. PMID 15073186 DOI: 10.1074/Jbc.M314323200  1
2003 Xiao L, Liu P, Sobue T, Lichtler A, Coffin JD, Hurley MM. Effect of overexpressing fibroblast growth factor 2 protein isoforms in osteoblastic ROS 17/2.8 cells. Journal of Cellular Biochemistry. 89: 1291-301. PMID 12898525 DOI: 10.1002/Jcb.10589  0.72
2003 Okada Y, Montero A, Zhang X, Sobue T, Lorenzo J, Doetschman T, Coffin JD, Hurley MM. Impaired osteoclast formation in bone marrow cultures of Fgf2 null mice in response to parathyroid hormone. The Journal of Biological Chemistry. 278: 21258-66. PMID 12665515 DOI: 10.1074/Jbc.M302113200  0.4
2003 Kalajzic I, Kalajzic Z, Hurley MM, Lichtler AC, Rowe DW. Stage specific inhibition of osteoblast lineage differentiation by FGF2 and noggin. Journal of Cellular Biochemistry. 88: 1168-76. PMID 12647299 DOI: 10.1002/Jcb.10459  1
2000 Montero A, Okada Y, Tomita M, Ito M, Tsurukami H, Nakamura T, Doetschman T, Coffin JD, Hurley MM. Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation. The Journal of Clinical Investigation. 105: 1085-93. PMID 10772653 DOI: 10.1172/Jci8641  0.4
1999 Hurley MM, Tetradis S, Huang YF, Hock J, Kream BE, Raisz LG, Sabbieti MG. Parathyroid hormone regulates the expression of fibroblast growth factor-2 mRNA and fibroblast growth factor receptor mRNA in osteoblastic cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 14: 776-83. PMID 10320526 DOI: 10.1359/Jbmr.1999.14.5.776  1
1999 Sabbieti MG, Marchetti L, Abreu C, Montero A, Hand AR, Raisz LG, Hurley MM. Prostaglandins regulate the expression of fibroblast growth factor-2 in bone. Endocrinology. 140: 434-44. PMID 9886855 DOI: 10.1210/Endo.140.1.6442  1
1996 Hurley MM, Abreu C, Marcello K, Kawaguchi H, Lorenzo J, Kalinowski J, Ray A, Gronowicz G. Regulation of NFIL-6 and IL-6 expression by basic fibroblast growth factor in osteoblasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 11: 760-7. PMID 8725173 DOI: 10.1002/Jbmr.5650110607  0.48
1996 Hakeda Y, Kawaguchi H, Hurley M, Pilbeam CC, Abreu C, Linkhart TA, Mohan S, Kumegawa M, Raisz LG. Intact insulin-like growth factor binding protein-5 (IGFBP-5) associates with bone matrix and the soluble fragments of IGFBP-5 accumulated in culture medium of neonatal mouse calvariae by parathyroid hormone and prostaglandin E2-treatment Journal of Cellular Physiology. 166: 370-379. PMID 8591997 DOI: 10.1002/(Sici)1097-4652(199602)166:2<370::Aid-Jcp15>3.0.Co;2-F  1
1995 Kawaguchi H, Pilbeam CC, Gronowicz G, Abreu C, Fletcher BS, Herschman HR, Raisz LG, Hurley MM. Transcriptional induction of prostaglandin G/H synthase-2 by basic fibroblast growth factor. The Journal of Clinical Investigation. 96: 923-30. PMID 7635987 DOI: 10.1172/Jci118140  1
1992 Hurley MM, Kessler M, Gronowicz G, Raisz LG. The interaction of heparin and basic fibroblast growth factor on collagen synthesis in 21-day fetal rat calvariae. Endocrinology. 130: 2675-82. PMID 1374012 DOI: 10.1210/Endo.130.5.1374012  0.48
1990 Hurley MM, Martin DL, Kream BE, Raisz LG. Effects of ethanol and acetaldehyde on collagen synthesis, prostaglandin release and resorption of fetal rat bone in organ culture. Bone. 11: 47-51. PMID 2331431 DOI: 10.1016/8756-3282(90)90071-6  1
1990 Hurley MM, Kream BE, Raisz LG. Structural determinants of the capacity of heparin to inhibit collagen synthesis in 21-day fetal rat calvariae. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 5: 1127-33. PMID 2176772 DOI: 10.1002/Jbmr.5650051106  1
1990 Hurley MM, Gronowicz G, Kream BE, Raisz LG. Effect of heparin on bone formation in cultured fetal rat calvaria. Calcified Tissue International. 46: 183-8. PMID 2106377 DOI: 10.1007/Bf02555042  1
1989 Hurley MM, Fall P, Harrison JR, Petersen DN, Kream BE, Raisz LG. Effects of transforming growth factor alpha and interleukin-1 on DNA synthesis, collagen synthesis, procollagen mRNA levels, and prostaglandin E2 production in cultured fetal rat calvaria. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 4: 731-6. PMID 2816517 DOI: 10.1002/Jbmr.5650040512  1
1987 Vargas SJ, Jones TG, Hurley MM, Raisz LG. Comparison of the effects of auranofin, gold sodium thiomalate, and penicillamine on resorption of cultured fetal rat long bones. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 2: 183-9. PMID 3137774 DOI: 10.1002/Jbmr.5650020304  1
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