Brian R. Wamhoff - Publications

University of Virginia, Charlottesville, VA 
Molecular Biology, Physiology Biology, Cell Biology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Shepherd EL, Saborano R, Northall E, Matsuda K, Ogino H, Yashiro H, Pickens J, Feaver RE, Cole BK, Hoang SA, Lawson MJ, Olson M, Figler RA, Reardon JE, Nishigaki N, ... Wamhoff BR, et al. Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis. Jhep Reports : Innovation in Hepatology. 3: 100217. PMID 33490936 DOI: 10.1016/j.jhepr.2020.100217  0.32
2019 Hoang SA, Oseini A, Feaver RE, Cole BK, Asgharpour A, Vincent R, Siddiqui M, Lawson MJ, Day NC, Taylor JM, Wamhoff BR, Mirshahi F, Contos MJ, Idowu M, Sanyal AJ. Gene Expression Predicts Histological Severity and Reveals Distinct Molecular Profiles of Nonalcoholic Fatty Liver Disease. Scientific Reports. 9: 12541. PMID 31467298 DOI: 10.1038/S41598-019-48746-5  0.32
2017 Cole BK, Feaver RE, Wamhoff BR, Dash A. Non-alcoholic fatty liver disease (NAFLD) models in drug discovery. Expert Opinion On Drug Discovery. 1-13. PMID 29190166 DOI: 10.1080/17460441.2018.1410135  0.32
2017 Collado MS, Cole BK, Figler RA, Lawson M, Manka D, Simmers MB, Hoang S, Serrano F, Blackman BR, Sinha S, Wamhoff BR. Exposure of Induced Pluripotent Stem Cell-Derived Vascular Endothelial and Smooth Muscle Cells in Coculture to Hemodynamics Induces Primary Vascular Cell-Like Phenotypes. Stem Cells Translational Medicine. PMID 28628273 DOI: 10.1002/Sctm.17-0004  0.32
2016 Feaver RE, Cole BK, Lawson MJ, Hoang SA, Marukian S, Blackman BR, Figler RA, Sanyal AJ, Wamhoff BR, Dash A. Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis. Jci Insight. 1: e90954. PMID 27942596 DOI: 10.1172/Jci.Insight.90954  0.32
2016 Dash A, Figler RA, Blackman BR, Marukian S, Collado MS, Lawson MJ, Hoang SA, Mackey AJ, Manka D, Cole BK, Feaver RE, Sanyal AJ, Wamhoff BR. Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 27939613 DOI: 10.1016/J.Tiv.2016.11.014  0.32
2016 Simmers MB, Cole BK, Ogletree ML, Chen Z, Xu Y, Kong LJ, Mackman N, Blackman BR, Wamhoff BR. Hemodynamics associated with atrial fibrillation directly alters thrombotic potential of endothelial cells. Thrombosis Research. 143: 34-39. PMID 27179130 DOI: 10.1016/J.Thromres.2016.04.022  0.4
2015 Chapman KA, Collado MS, Figler RA, Hoang SA, Armstrong AJ, Cui W, Purdy M, Simmers MB, Yazigi NA, Summar ML, Wamhoff BR, Dash A. Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytes. Molecular Genetics and Metabolism. PMID 26740382 DOI: 10.1016/J.Ymgme.2015.12.008  0.4
2015 Terelius Y, Figler RA, Marukian S, Collado MS, Lawson MJ, Mackey AJ, Manka D, Qualls CW, Blackman BR, Wamhoff BR, Dash A. Transcriptional Profiling Suggests That Nevirapine and Ritonavir Cause Drug Induced Liver Injury Through Distinct Mechanisms in Primary Human Hepatocytes. Chemico-Biological Interactions. PMID 26626330 DOI: 10.1016/J.Cbi.2015.11.023  0.4
2015 Dixon AJ, Kilroy JP, Dhanaliwala AH, Chen JL, Phillips LC, Ragosta M, Klibanov AL, Wamhoff BR, Hossack JA. Microbubble-mediated intravascular ultrasound imaging and drug delivery. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. 62: 1674-85. PMID 26415129 DOI: 10.1109/Tuffc.2015.007143  0.4
2015 Cole BK, Simmers MB, Feaver R, Qualls CW, Collado MS, Berzin E, Figler RA, Pryor AW, Lawson M, Mackey A, Manka D, Wamhoff BR, Turk JR, Blackman BR. An In Vitro Cynomolgus Vascular Surrogate System for Preclinical Drug Assessment and Human Translation. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 2185-95. PMID 26293464 DOI: 10.1161/Atvbaha.115.306245  0.4
2015 Kilroy JP, Dhanaliwala AH, Klibanov AL, Bowles DK, Wamhoff BR, Hossack JA. Reducing Neointima Formation in a Swine Model with IVUS and Sirolimus Microbubbles. Annals of Biomedical Engineering. 43: 2642-51. PMID 25893508 DOI: 10.1007/S10439-015-1315-6  0.4
2014 Kilroy JP, Klibanov AL, Wamhoff BR, Bowles DK, Hossack JA. Localized in vivo model drug delivery with intravascular ultrasound and microbubbles. Ultrasound in Medicine & Biology. 40: 2458-67. PMID 25130449 DOI: 10.1016/J.Ultrasmedbio.2014.04.007  0.4
2014 Kilroy JP, Dhanaliwala AH, Wamhoff BR, Klibanov AL, Bowles DK, Hossack JA. Neointima reduction with IVUS and rapamycin microbubbles: In Vivo swine model results Ieee International Ultrasonics Symposium, Ius. 13-16. DOI: 10.1109/ULTSYM.2014.0004  0.4
2013 Dash A, Simmers MB, Deering TG, Berry DJ, Feaver RE, Hastings NE, Pruett TL, LeCluyse EL, Blackman BR, Wamhoff BR. Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro. American Journal of Physiology. Cell Physiology. 304: C1053-63. PMID 23485712 DOI: 10.1152/Ajpcell.00331.2012  0.4
2012 Halterman JA, Kwon HM, Leitinger N, Wamhoff BR. NFAT5 expression in bone marrow-derived cells enhances atherosclerosis and drives macrophage migration. Frontiers in Physiology. 3: 313. PMID 22934063 DOI: 10.3389/Fphys.2012.00313  0.48
2012 Dash A, Blackman BR, Wamhoff BR. Organotypic systems in drug metabolism and toxicity: challenges and opportunities. Expert Opinion On Drug Metabolism & Toxicology. 8: 999-1014. PMID 22632603 DOI: 10.1517/17425255.2012.693161  0.32
2012 Halterman JA, Kwon HM, Wamhoff BR. Tonicity-independent regulation of the osmosensitive transcription factor TonEBP (NFAT5). American Journal of Physiology. Cell Physiology. 302: C1-8. PMID 21998140 DOI: 10.1152/Ajpcell.00327.2011  0.48
2011 Schoppee Bortz PD, Wamhoff BR. Chromatin immunoprecipitation (ChIP): revisiting the efficacy of sample preparation, sonication, quantification of sheared DNA, and analysis via PCR. Plos One. 6: e26015. PMID 22046253 DOI: 10.1371/journal.pone.0026015  0.44
2011 Lee MY, Garvey SM, Ripley ML, Wamhoff BR. Genome-wide microarray analyses identify the protein C receptor as a novel calcineurin/nuclear factor of activated T cells-dependent gene in vascular smooth muscle cell phenotypic modulation. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2665-75. PMID 21903947 DOI: 10.1161/Atvbaha.111.235960  0.4
2011 Halterman JA, Kwon HM, Zargham R, Bortz PD, Wamhoff BR. Nuclear factor of activated T cells 5 regulates vascular smooth muscle cell phenotypic modulation. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2287-96. PMID 21757659 DOI: 10.1161/Atvbaha.111.232165  0.48
2011 Gelfand BD, Meller J, Pryor AW, Kahn M, Bortz PD, Wamhoff BR, Blackman BR. Hemodynamic activation of beta-catenin and T-cell-specific transcription factor signaling in vascular endothelium regulates fibronectin expression. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1625-33. PMID 21527747 DOI: 10.1161/Atvbaha.111.227827  0.4
2011 Sefcik LS, Aronin CE, Awojoodu AO, Shin SJ, Mac Gabhann F, MacDonald TL, Wamhoff BR, Lynch KR, Peirce SM, Botchwey EA. Selective activation of sphingosine 1-phosphate receptors 1 and 3 promotes local microvascular network growth. Tissue Engineering. Part A. 17: 617-29. PMID 20874260 DOI: 10.1089/Ten.Tea.2010.0404  0.4
2010 Kadl A, Meher AK, Sharma PR, Lee MY, Doran AC, Johnstone SR, Elliott MR, Gruber F, Han J, Chen W, Kensler T, Ravichandran KS, Isakson BE, Wamhoff BR, Leitinger N. Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circulation Research. 107: 737-46. PMID 20651288 DOI: 10.1161/Circresaha.109.215715  0.4
2010 Mathews TP, Kennedy AJ, Kharel Y, Kennedy PC, Nicoara O, Sunkara M, Morris AJ, Wamhoff BR, Lynch KR, Macdonald TL. Discovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitors. Journal of Medicinal Chemistry. 53: 2766-78. PMID 20205392 DOI: 10.1021/Jm901860H  0.4
2010 Garvey SM, Sinden DS, Schoppee Bortz PD, Wamhoff BR. Cyclosporine up-regulates Krüppel-like factor-4 (KLF4) in vascular smooth muscle cells and drives phenotypic modulation in vivo. The Journal of Pharmacology and Experimental Therapeutics. 333: 34-42. PMID 20089806 DOI: 10.1124/Jpet.109.163949  0.44
2010 Petrie Aronin CE, Sefcik LS, Tholpady SS, Tholpady A, Sadik KW, Macdonald TL, Peirce SM, Wamhoff BR, Lynch KR, Ogle RC, Botchwey EA. FTY720 promotes local microvascular network formation and regeneration of cranial bone defects. Tissue Engineering. Part A. 16: 1801-9. PMID 20038198 DOI: 10.1089/Ten.Tea.2009.0539  0.4
2010 Nilsson-Berglund LM, Zetterqvist AV, Nilsson-Ohman J, Sigvardsson M, González Bosc LV, Smith ML, Salehi A, Agardh E, Fredrikson GN, Agardh CD, Nilsson J, Wamhoff BR, HultgÃ¥rdh-Nilsson A, Gomez MF. Nuclear factor of activated T cells regulates osteopontin expression in arterial smooth muscle in response to diabetes-induced hyperglycemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 218-24. PMID 19965778 DOI: 10.1161/Atvbaha.109.199299  0.4
2010 Lee MY, Garvey SM, Baras AS, Lemmon JA, Gomez MF, Schoppee Bortz PD, Daum G, LeBoeuf RC, Wamhoff BR. Integrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells. Human Molecular Genetics. 19: 468-79. PMID 19926569 DOI: 10.1161/Atv.0B013E3181Ab66E7  0.4
2010 Phillips LC, Klibanov AL, Bowles DK, Ragosta M, Hossack JA, Wamhoff BR. Focused in vivo delivery of plasmid DNA to the porcine vascular wall via intravascular ultrasound destruction of microbubbles. Journal of Vascular Research. 47: 270-4. PMID 19923850 DOI: 10.1159/000258905  0.4
2010 Orr AW, Hastings NE, Blackman BR, Wamhoff BR. Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis. Journal of Vascular Research. 47: 168-80. PMID 19851078 DOI: 10.1159/000250095  0.4
2010 Kilroy JP, Patil AV, Klibanov AL, Wamhoff BR, Rychak JJ, Hossack JA. Localized ex-vivo microbubble-based model drug delivery using an ultrasound catheter Proceedings - Ieee Ultrasonics Symposium. 674-677. DOI: 10.1109/ULTSYM.2010.5935936  0.4
2009 Long X, Tharp DL, Georger MA, Slivano OJ, Lee MY, Wamhoff BR, Bowles DK, Miano JM. The smooth muscle cell-restricted KCNMB1 ion channel subunit is a direct transcriptional target of serum response factor and myocardin. The Journal of Biological Chemistry. 284: 33671-82. PMID 19801679 DOI: 10.1074/Jbc.M109.050419  0.4
2009 Hastings NE, Feaver RE, Lee MY, Wamhoff BR, Blackman BR. Human IL-8 regulates smooth muscle cell VCAM-1 expression in response to endothelial cells exposed to atheroprone flow. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 725-31. PMID 19229069 DOI: 10.1161/Atvbaha.109.184382  0.4
2009 Thomas JA, Deaton RA, Hastings NE, Shang Y, Moehle CW, Eriksson U, Topouzis S, Wamhoff BR, Blackman BR, Owens GK. PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns. American Journal of Physiology. Heart and Circulatory Physiology. 296: H442-52. PMID 19028801 DOI: 10.1152/Ajpheart.00165.2008  0.4
2009 Orr AW, Lee MY, Lemmon JA, Yurdagul A, Gomez MF, Bortz PD, Wamhoff BR. Molecular mechanisms of collagen isotype-specific modulation of smooth muscle cell phenotype. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 225-31. PMID 19023090 DOI: 10.1161/Atvbaha.108.178749  0.4
2009 Acton ST, Yang C, Hossack JA, Wamhoff BR. Poisson inverse gradient approach to vascular myocyte detection and segmentation Proceedings - 2009 Ieee International Symposium On Biomedical Imaging: From Nano to Macro, Isbi 2009. 1298-1301. DOI: 10.1109/ISBI.2009.5193302  0.4
2008 Lemmon JA, Wamhoff BR. "FRNKly, smooth muscle, I don't give a CArG!": a novel mechanism for smooth muscle cell differentiation. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2091-3. PMID 19020312 DOI: 10.1161/Atvbaha.108.176875  0.4
2008 Wamhoff BR, Lynch KR, Macdonald TL, Owens GK. Sphingosine-1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1454-61. PMID 18535287 DOI: 10.1161/Atvbaha.107.159392  0.4
2008 Tharp DL, Wamhoff BR, Wulff H, Raman G, Cheong A, Bowles DK. Local delivery of the K Ca3.1 blocker, TRAM-34, prevents acute angioplasty-induced coronary smooth muscle phenotypic modulation and limits stenosis Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1084-1089. PMID 18309114 DOI: 10.1161/Atvbaha.107.155796  0.4
2007 Hastings NE, Simmers MB, McDonald OG, Wamhoff BR, Blackman BR. Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming. American Journal of Physiology. Cell Physiology. 293: C1824-33. PMID 17913848 DOI: 10.1152/Ajpcell.00385.2007  0.4
2007 Jin L, Kern MJ, Otey CA, Wamhoff BR, Somlyo AV. Angiotensin II, focal adhesion kinase, and PRX1 enhance smooth muscle expression of lipoma preferred partner and its newly identified binding partner palladin to promote cell migration. Circulation Research. 100: 817-25. PMID 17322171 DOI: 10.1161/01.Res.0000261351.54147.De  0.4
2006 Sinha S, Wamhoff BR, Hoofnagle MH, Thomas J, Neppl RL, Deering T, Helmke BP, Bowles DK, Somlyo AV, Owens GK. Assessment of contractility of purified smooth muscle cells derived from embryonic stem cells. Stem Cells (Dayton, Ohio). 24: 1678-88. PMID 16601077 DOI: 10.1634/Stemcells.2006-0002  0.4
2005 Hendrix JA, Wamhoff BR, McDonald OG, Sinha S, Yoshida T, Owens GK. 5' CArG degeneracy in smooth muscle alpha-actin is required for injury-induced gene suppression in vivo. The Journal of Clinical Investigation. 115: 418-27. PMID 15690088 DOI: 10.1172/Jci22648  0.4
2004 Wamhoff BR, Bowles DK, McDonald OG, Sinha S, Somlyo AP, Somlyo AV, Owens GK. L-type voltage-gated Ca2+ channels modulate expression of smooth muscle differentiation marker genes via a rho kinase/myocardin/SRF-dependent mechanism. Circulation Research. 95: 406-14. PMID 15256479 DOI: 10.1161/01.Res.0000138582.36921.9E  0.4
2003 Lee DL, Wamhoff BR, Katwa LC, Reddy HK, Voelker DJ, Dixon JL, Sturek M. Increased endothelin-induced Ca2+ signaling, tyrosine phosphorylation, and coronary artery disease in diabetic dyslipidemic Swine are prevented by atorvastatin. The Journal of Pharmacology and Experimental Therapeutics. 306: 132-40. PMID 12663685 DOI: 10.1124/Jpet.103.049577  0.4
2002 Wamhoff BR, Bowles DK, Dietz NJ, Hu Q, Sturek M. Exercise training attenuates coronary smooth muscle phenotypic modulation and nuclear Ca2+ signaling American Journal of Physiology - Heart and Circulatory Physiology. 283. PMID 12388302 DOI: 10.1152/Ajpheart.00371.2001  0.4
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