Kenneth H. Cowan - Publications

Affiliations: 
Cancer and Allied Diseases University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Molecular Biology, Oncology, Cell Biology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yan Y, Haas JP, Kim M, Sgagias MK, Cowan KH. Withdrawal: BRCA1-induced apoptosis involves inactivation of ERK1/2 activities. The Journal of Biological Chemistry. 294: 8309. PMID 31101659 DOI: 10.1074/jbc.W119.009053  0.72
2018 Razidlo GL, Johnson HJ, Stoeger SM, Cowan KH, Bessho T, Lewis RE. Correction: KSR1 is required for cell cycle reinitiation following DNA damage. The Journal of Biological Chemistry. 293: 19136. PMID 30530853 DOI: 10.1074/jbc.AAC118.006696  1
2015 Bevers TB, Ward JH, Arun BK, Colditz GA, Cowan KH, Daly MB, Garber JE, Gemignani ML, Gradishar WJ, Jordan JA, Korde LA, Kounalakis N, Krontiras H, Kumar S, Kurian A, et al. Breast Cancer Risk Reduction, Version 2.2015. Journal of the National Comprehensive Cancer Network : Jnccn. 13: 880-915. PMID 26150582  1
2015 Downs B, Kim YC, Xiao F, Snyder C, Chen P, Fleissner EA, Becirovic D, Wen H, Sherman S, Cowan KH, Lynch HT, Wang SM. Two PALB2 germline mutations found in both BRCA1+ and BRCAx familial breast cancer. Breast Cancer Research and Treatment. 151: 219-24. PMID 25833210 DOI: 10.1007/s10549-015-3358-7  1
2015 Li Y, Wang X, Vural S, Mishra NK, Cowan KH, Guda C. Exome analysis reveals differentially mutated gene signatures of stage, grade and subtype in breast cancers. Plos One. 10: e0119383. PMID 25803781 DOI: 10.1371/journal.pone.0119383  1
2015 Yan Y, Hein AL, Greer PM, Wang Z, Kolb RH, Batra SK, Cowan KH. A novel function of HER2/Neu in the activation of G2/M checkpoint in response to γ-irradiation. Oncogene. 34: 2215-26. PMID 24909175 DOI: 10.1038/onc.2014.167  1
2014 Yan Y, Hein AL, Etekpo A, Burchett KM, Lin C, Enke CA, Batra SK, Cowan KH, Ouellette MM. Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation. Oncotarget. 5: 10251-70. PMID 25344910  1
2014 Wen H, Kim YC, Snyder C, Xiao F, Fleissner EA, Becirovic D, Luo J, Downs B, Sherman S, Cowan KH, Lynch HT, Wang SM. Family-specific, novel, deleterious germline variants provide a rich resource to identify genetic predispositions for BRCAx familial breast cancer. Bmc Cancer. 14: 470. PMID 24969172 DOI: 10.1186/1471-2407-14-470  1
2014 Xiao F, Kim YC, Snyder C, Wen H, Chen PX, Luo J, Becirovic D, Downs B, Cowan KH, Lynch H, Wang SM. Genome instability in blood cells of a BRCA1+ breast cancer family. Bmc Cancer. 14: 342. PMID 24884718 DOI: 10.1186/1471-2407-14-342  1
2013 Lynch H, Wen H, Kim YC, Snyder C, Kinarsky Y, Chen PX, Xiao F, Goldgar D, Cowan KH, Wang SM. Can unknown predisposition in familial breast cancer be family-specific? The Breast Journal. 19: 520-8. PMID 23800003 DOI: 10.1111/tbj.12145  1
2012 Kolb RH, Greer PM, Cao PT, Cowan KH, Yan Y. ERK1/2 signaling plays an important role in topoisomerase II poison-induced G2/M checkpoint activation. Plos One. 7: e50281. PMID 23166842 DOI: 10.1371/journal.pone.0050281  1
2012 Yan Y, Greer PM, Cao PT, Kolb RH, Cowan KH. RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation. Breast Cancer Research : Bcr. 14: R60. PMID 22494620 DOI: 10.1186/bcr3164  1
2010 Bevers TB, Armstrong DK, Arun B, Carlson RW, Cowan KH, Daly MB, Fleming I, Garber JE, Gemignani M, Gradishar WJ, Krontiras H, Kulkarni S, Laronga C, Loftus L, Macdonald DJ, et al. Breast cancer risk reduction. Journal of the National Comprehensive Cancer Network : Jnccn. 8: 1112-46. PMID 20971838  1
2010 Yan Y, Cao PT, Greer PM, Nagengast ES, Kolb RH, Mumby MC, Cowan KH. Protein phosphatase 2A has an essential role in the activation of gamma-irradiation-induced G2/M checkpoint response. Oncogene. 29: 4317-29. PMID 20498628 DOI: 10.1038/onc.2010.187  1
2009 Talmadge JE, Cowan KH, Reed EC. Tumor and iatrogenic regulation of myeloid precursors and their potential to limit immune therapy. Immunotherapy. 1: 5-9. PMID 20635966 DOI: 10.2217/1750743X.1.1.5  1
2009 Razidlo GL, Johnson HJ, Stoeger SM, Cowan KH, Bessho T, Lewis RE. KSR1 is required for cell cycle reinitiation following DNA damage. The Journal of Biological Chemistry. 284: 6705-15. PMID 19147494 DOI: 10.1074/jbc.M806457200  1
2009 Stoeger SM, Cowan KH. Characterization of kinase suppressor of Ras-1 expression and anticancer drug sensitivity in human cancer cell lines. Cancer Chemotherapy and Pharmacology. 63: 807-18. PMID 18661133 DOI: 10.1007/s00280-008-0794-7  1
2008 Yan Y, Black CP, Cao PT, Haferbier JL, Kolb RH, Spieker RS, Ristow AM, Cowan KH. Gamma-irradiation-induced DNA damage checkpoint activation involves feedback regulation between extracellular signal-regulated kinase 1/2 and BRCA1. Cancer Research. 68: 5113-21. PMID 18593910 DOI: 10.1158/0008-5472.CAN-07-5818  1
2007 Bevers TB, Armstrong DK, Arun B, Carlson RW, Cowan KH, Daly MB, Fleming I, Garber JE, Gemignani M, Gradishar WJ, Krontiras H, Kulkarni S, Laronga C, Lawton T, Loftus L, et al. Breast cancer risk reduction. Journal of the National Comprehensive Cancer Network : Jnccn. 5: 676-701. PMID 17927926  1
2007 Yaar M, Eller MS, Panova I, Kubera J, Wee LH, Cowan KH, Gilchrest BA. Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells. Breast Cancer Research : Bcr. 9: R13. PMID 17257427 DOI: 10.1186/bcr1646  1
2006 Muraoka-Cook RS, Caskey LS, Sandahl MA, Hunter DM, Husted C, Strunk KE, Sartor CI, Rearick WA, McCall W, Sgagias MK, Cowan KH, Earp HS. Heregulin-dependent delay in mitotic progression requires HER4 and BRCA1. Molecular and Cellular Biology. 26: 6412-24. PMID 16914727 DOI: 10.1128/MCB.01950-05  1
2006 Das AV, Zhao X, James J, Kim M, Cowan KH, Ahmad I. Neural stem cells in the adult ciliary epithelium express GFAP and are regulated by Wnt signaling. Biochemical and Biophysical Research Communications. 339: 708-16. PMID 16332461 DOI: 10.1016/j.bbrc.2005.11.064  1
2005 Basma H, El-Refaey H, Sgagias MK, Cowan KH, Luo X, Cheng PW. BCL-2 antisense and cisplatin combination treatment of MCF-7 breast cancer cells with or without functional p53. Journal of Biomedical Science. 12: 999-1011. PMID 16228292 DOI: 10.1007/s11373-005-9025-y  1
2005 Kim M, Yan Y, Kortum RL, Stoeger SM, Sgagias MK, Lee K, Lewis RE, Cowan KH. Expression of kinase suppressor of Ras1 enhances cisplatin-induced extracellular signal-regulated kinase activation and cisplatin sensitivity. Cancer Research. 65: 3986-92. PMID 15899786 DOI: 10.1158/0008-5472.CAN-03-2334  1
2005 Yan Y, Spieker RS, Kim M, Stoeger SM, Cowan KH. BRCA1-mediated G2/M cell cycle arrest requires ERK1/2 kinase activation. Oncogene. 24: 3285-96. PMID 15735702 DOI: 10.1038/sj.onc.1208492  1
2004 Sgagias MK, Wagner KU, Hamik B, Stoeger S, Spieker R, Huber LJ, Chodosh LA, Cowan KH. Brca1-deficient murine mammary epithelial cells have increased sensitivity to CDDP and MMS. Cell Cycle (Georgetown, Tex.). 3: 1451-6. PMID 15492509  1
2004 Kim M, Yan Y, Lee K, Sgagias M, Cowan KH. Ectopic expression of von Hippel-Lindau tumor suppressor induces apoptosis in 786-O renal cell carcinoma cells and regresses tumor growth of 786-O cells in nude mouse. Biochemical and Biophysical Research Communications. 320: 945-50. PMID 15240140 DOI: 10.1016/j.bbrc.2004.06.042  1
2004 Nozawa F, Itami A, Saruc M, Kim M, Standop J, Picha KS, Cowan KH, Pour PM. The combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) and Genistein is effective in inhibiting pancreatic cancer growth. Pancreas. 29: 45-52. PMID 15211111 DOI: 10.1097/00006676-200407000-00055  1
2003 Yamamoto K, Katayose Y, Suzuki M, Unno M, Sasaki T, Mizuma M, Shiraso S, Ohtuka H, Cowan KH, Seth P, Matsuno S. Adenovirus expressing p27KIP1 induces apoptosis against cholangiocarcinoma cells by triggering Fas ligand on the cell surface. Hepato-Gastroenterology. 50: 1847-53. PMID 14696417  1
2003 Zujewski JA, Eng-Wong J, O'Shaughnessy J, Venzon D, Chow C, Danforth D, Kohler DR, Cusack G, Riseberg D, Cowan KH. A pilot study of dose intense doxorubicin and cyclophosphamide followed by infusional paclitaxel in high-risk primary breast cancer. Breast Cancer Research and Treatment. 81: 41-51. PMID 14531496 DOI: 10.1023/A:1025421416674  1
2002 Deng X, Kim M, Vandier D, Jung YJ, Rikiyama T, Sgagias MK, Goldsmith M, Cowan KH. Recombinant adenovirus-mediated p14(ARF) overexpression sensitizes human breast cancer cells to cisplatin. Biochemical and Biophysical Research Communications. 296: 792-8. PMID 12200117 DOI: 10.1016/S0006-291X(02)00948-8  1
2002 Yan Y, Haas JP, Kim M, Sgagias MK, Cowan KH. BRCA1-induced apoptosis involves inactivation of ERK1/2 activities. The Journal of Biological Chemistry. 277: 33422-30. PMID 12082091 DOI: 10.1074/jbc.M201147200  1
2002 Yarden RI, Pardo-Reoyo S, Sgagias M, Cowan KH, Brody LC. BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage. Nature Genetics. 30: 285-9. PMID 11836499 DOI: 10.1038/ng837  1
1995 Yokomizo A, Kohno K, Wada M, Ono M, Morrow CS, Cowan KH, Kuwano M. Markedly decreased expression of glutathione S-transferase pi gene in human cancer cell lines resistant to buthionine sulfoximine, an inhibitor of cellular glutathione synthesis. The Journal of Biological Chemistry. 270: 19451-7. PMID 7642628 DOI: 10.1074/jbc.270.33.19451  1
1994 Morrow CS, Nakagawa M, Goldsmith ME, Madden MJ, Cowan KH. Reversible transcriptional activation of mdr1 by sodium butyrate treatment of human colon cancer cells. The Journal of Biological Chemistry. 269: 10739-46. PMID 7908296  1
1993 Madden MJ, Morrow CS, Nakagawa M, Goldsmith ME, Fairchild CR, Cowan KH. Identification of 5' and 3' sequences involved in the regulation of transcription of the human mdr1 gene in vivo. The Journal of Biological Chemistry. 268: 8290-7. PMID 8096520  1
1993 Goldsmith ME, Madden MJ, Morrow CS, Cowan KH. A Y-box consensus sequence is required for basal expression of the human multidrug resistance (mdr1) gene. The Journal of Biological Chemistry. 268: 5856-60. PMID 8095499  1
1993 Morrow CS, Cowan KH. Antineoplastic drug resistance and breast cancer. Annals of the New York Academy of Sciences. 698: 289-312. PMID 7904140  1
1992 Morrow CS, Chiu J, Cowan KH. Posttranscriptional control of glutathione S-transferase pi gene expression in human breast cancer cells. The Journal of Biological Chemistry. 267: 10544-50. PMID 1587835  1
1992 Moscow JA, Morrow CS, He R, Mullenbach GT, Cowan KH. Structure and function of the 5'-flanking sequence of the human cytosolic selenium-dependent glutathione peroxidase gene (hgpx1). The Journal of Biological Chemistry. 267: 5949-58. PMID 1556108  1
1992 Moscow JA, Morrow CS, Cowan KH. Multidrug resistance. Cancer Chemotherapy and Biological Response Modifiers. 13: 91-114. PMID 1356403  1
1991 Townsend AJ, Morrow CS, Sinha BK, Cowan KH. Selenium-dependent glutathione peroxidase expression is inversely related to estrogen receptor content of human breast cancer cells. Cancer Communications. 3: 265-70. PMID 1653587  1
1990 Morrow CS, Cowan KH. Glutathione S-transferases and drug resistance. Cancer Cells (Cold Spring Harbor, N.Y. : 1989). 2: 15-22. PMID 2201336  1
1990 Morrow CS, Cowan KH. Multidrug resistance associated with altered topoisomerase II activity--topoisomerases II as targets for rational drug design. Journal of the National Cancer Institute. 82: 638-9. PMID 2157026 DOI: 10.1093/jnci/82.8.638  1
1990 Morrow CS, Goldsmith ME, Cowan KH. Regulation of human glutathione S-transferase pi gene transcription: influence of 5'-flanking sequences and trans-activating factors which recognize AP-1-binding sites. Gene. 88: 215-25. PMID 2112105 DOI: 10.1016/0378-1119(90)90034-O  1
1989 Morrow CS, Cowan KH, Goldsmith ME. Structure of the human genomic glutathione S-transferase-pi gene. Gene. 75: 3-11. PMID 2542132 DOI: 10.1016/0378-1119(89)90377-6  1
1988 Morrow CS, Cowan KH. Mechanisms and clinical significance of multidrug resistance. Oncology (Williston Park, N.Y.). 2: 55-63, 66-8. PMID 3079288  1
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