Merril E. Gershwin - Publications

Affiliations: 
Immunology University of California, Davis, Davis, CA 
Area:
Immunology, Pathology, Cell Biology

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Li B, Selmi C, Tang R, Gershwin ME, Ma X. The microbiome and autoimmunity: a paradigm from the gut-liver axis. Cellular & Molecular Immunology. PMID 29706647 DOI: 10.1038/cmi.2018.7  0.335
2018 Zhang W, Zhang R, Zhang J, Sun Y, Leung PS, Yang GX, Shuai Z, Ridgway WM, Gershwin ME. Proteomic analysis reveals distinctive protein profiles involved in CD8+ T cell-mediated murine autoimmune cholangitis. Cellular & Molecular Immunology. PMID 29375127 DOI: 10.1038/cmi.2017.149  0.317
2016 Uchida K, Tanaka T, Gershwin ME, Okazaki K. The Geoepidemiology and Clinical Aspects of IgG4-Related Disease. Seminars in Liver Disease. 36: 187-199. PMID 27466790 DOI: 10.1055/s-0036-1584323  0.304
2016 Arsenijevic A, Milovanovic M, Milovanovic J, Stojanovic B, Zdravkovic N, Leung PS, Liu FT, Gershwin ME, Lukic ML. Deletion of Galectin-3 Enhances Xenobiotic Induced Murine Primary Biliary Cholangitis by Facilitating Apoptosis of BECs and Release of Autoantigens. Scientific Reports. 6: 23348. PMID 26996208 DOI: 10.1038/Srep23348  0.355
2016 Leung PS, Choi J, Yang G, Woo E, Kenny TP, Gershwin ME. A contemporary perspective on the molecular characteristics of mitochondrial autoantigens and diagnosis in primary biliary cholangitis. Expert Review of Molecular Diagnostics. PMID 26953925 DOI: 10.1586/14737159.2016.1164038  0.322
2015 Floreani A, Sun Y, Zou ZS, Li B, Cazzagon N, Bowlus CL, Gershwin ME. Proposed therapies in primary biliary cholangitis. Expert Review of Gastroenterology & Hepatology. PMID 26577047 DOI: 10.1586/17474124.2016.1121810  0.323
2015 Beuers U, Gershwin ME. Unmet challenges in immune-mediated hepatobiliary diseases. Clinical Reviews in Allergy & Immunology. 48: 127-31. PMID 25820618 DOI: 10.1007/s12016-015-8484-9  0.348
2015 Chang CH, Chen YC, Zhang W, Leung PS, Gershwin ME, Chuang YH. Innate immunity drives the initiation of a murine model of primary biliary cirrhosis. Plos One. 10: e0121320. PMID 25807531 DOI: 10.1371/journal.pone.0121320  0.388
2015 Katsumi T, Tomita K, Leung PS, Yang GX, Gershwin ME, Ueno Y. Animal models of primary biliary cirrhosis. Clinical Reviews in Allergy & Immunology. 48: 142-53. PMID 25771770 DOI: 10.1007/s12016-015-8482-y  0.314
2015 Wang YH, Yang W, Yang JB, Jia YJ, Tang W, Gershwin ME, Ridgway WM, Lian ZX. Systems biologic analysis of T regulatory cells genetic pathways in murine primary biliary cirrhosis. Journal of Autoimmunity. 59: 26-37. PMID 25701076 DOI: 10.1016/J.Jaut.2015.01.011  0.314
2015 Sun Y, Zhang W, Li B, Zou Z, Selmi C, Gershwin ME. The coexistence of Sjögren's syndrome and primary biliary cirrhosis: a comprehensive review. Clinical Reviews in Allergy & Immunology. 48: 301-15. PMID 25682089 DOI: 10.1007/s12016-015-8471-1  0.323
2015 Li Y, Wang W, Tang L, He X, Yan X, Zhang X, Zhu Y, Sun J, Shi Y, Ma X, Mackay IR, Gershwin ME, Han Y, Hou J. Chemokine (C-X-C motif) ligand 13 promotes intrahepatic chemokine (C-X-C motif) receptor 5+ lymphocyte homing and aberrant B-cell immune responses in primary biliary cirrhosis. Hepatology (Baltimore, Md.). 61: 1998-2007. PMID 25627620 DOI: 10.1002/hep.27725  0.309
2015 Tanaka H, Yang GX, Tomiyama T, Tsuneyama K, Zhang W, Leung PS, Coppel RL, Joh T, Nadler SG, Ansari AA, Bowlus C, Gershwin ME. Immunological potential of cytotoxic T lymphocyte antigen 4 immunoglobulin in murine autoimmune cholangitis. Clinical and Experimental Immunology. 180: 371-82. PMID 25581259 DOI: 10.1111/Cei.12581  0.303
2015 Mousa HS, Lleo A, Invernizzi P, Bowlus CL, Gershwin ME. Advances in pharmacotherapy for primary biliary cirrhosis. Expert Opinion On Pharmacotherapy. 16: 633-43. PMID 25543678 DOI: 10.1517/14656566.2015.998650  0.367
2015 Ma HD, Wang YH, Chang C, Gershwin ME, Lian ZX. The intestinal microbiota and microenvironment in liver. Autoimmunity Reviews. 14: 183-91. PMID 25315744 DOI: 10.1016/j.autrev.2014.10.013  0.307
2015 Wang L, Sun Y, Zhang Z, Jia Y, Zou Z, Ding J, Li Y, Xu X, Jin L, Yang T, Li Z, Sun Y, Zhang JY, Lv S, Chen L, ... ... Gershwin ME, et al. CXCR5+ CD4+ T follicular helper cells participate in the pathogenesis of primary biliary cirrhosis. Hepatology (Baltimore, Md.). 61: 627-38. PMID 25042122 DOI: 10.1002/hep.27306  0.316
2014 Wang J, Yang GX, Tsuneyama K, Gershwin ME, Ridgway WM, Leung PS. Animal models of primary biliary cirrhosis. Seminars in Liver Disease. 34: 285-96. PMID 25057952 DOI: 10.1055/s-0034-1383728  0.335
2014 Zhang J, Zhang W, Leung PS, Bowlus CL, Dhaliwal S, Coppel RL, Ansari AA, Yang GX, Wang J, Kenny TP, He XS, Mackay IR, Gershwin ME. Ongoing activation of autoantigen-specific B cells in primary biliary cirrhosis. Hepatology (Baltimore, Md.). 60: 1708-16. PMID 25043065 DOI: 10.1002/Hep.27313  0.361
2014 Mayer CT, Ghorbani P, Kühl AA, Stüve P, Hegemann M, Berod L, Gershwin ME, Sparwasser T. Few Foxp3⁺ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity. European Journal of Immunology. 44: 2990-3002. PMID 25042334 DOI: 10.1002/eji.201344315  0.323
2014 Tanaka H, Zhang W, Yang GX, Ando Y, Tomiyama T, Tsuneyama K, Leung P, Coppel RL, Ansari AA, Lian ZX, Ridgway WM, Joh T, Gershwin ME. Successful immunotherapy of autoimmune cholangitis by adoptive transfer of forkhead box protein 3(+) regulatory T cells. Clinical and Experimental Immunology. 178: 253-61. PMID 25041369 DOI: 10.1111/Cei.12415  0.332
2014 Kurth MJ, Yokoi T, Gershwin ME. Halothane-induced hepatitis: paradigm or paradox for drug-induced liver injury. Hepatology (Baltimore, Md.). 60: 1473-5. PMID 24913773 DOI: 10.1002/Hep.27253  0.317
2014 Xiao X, Miao Q, Chang C, Gershwin ME, Ma X. Common variable immunodeficiency and autoimmunity--an inconvenient truth. Autoimmunity Reviews. 13: 858-64. PMID 24747700 DOI: 10.1016/j.autrev.2014.04.006  0.337
2014 Huang W, Kachapati K, Adams D, Wu Y, Leung PS, Yang GX, Zhang W, Ansari AA, Flavell RA, Gershwin ME, Ridgway WM. Murine autoimmune cholangitis requires two hits: cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells. Journal of Autoimmunity. 50: 123-34. PMID 24556277 DOI: 10.1016/J.Jaut.2014.01.034  0.366
2014 Chang CH, Chen YC, Yu YH, Tao MH, Leung PS, Ansari AA, Gershwin ME, Chuang YH. Innate immunity drives xenobiotic-induced murine autoimmune cholangitis. Clinical and Experimental Immunology. 177: 373-80. PMID 24547942 DOI: 10.1111/Cei.12298  0.35
2014 Bowlus CL, Gershwin ME. The diagnosis of primary biliary cirrhosis. Autoimmunity Reviews. 13: 441-4. PMID 24424173 DOI: 10.1016/J.Autrev.2014.01.041  0.339
2013 Leung PS, Wang J, Naiyanetr P, Kenny TP, Lam KS, Kurth MJ, Gershwin ME. Environment and primary biliary cirrhosis: electrophilic drugs and the induction of AMA. Journal of Autoimmunity. 41: 79-86. PMID 23352659 DOI: 10.1016/J.Jaut.2012.12.007  0.758
2013 Hirschfield GM, Gershwin ME. The immunobiology and pathophysiology of primary biliary cirrhosis. Annual Review of Pathology. 8: 303-30. PMID 23347352 DOI: 10.1146/annurev-pathol-020712-164014  0.413
2013 Gershwin ME, Leung PS, Ridgway WM, Coppel RL, Ansari AA. Reply: To PMID 22996325. Hepatology (Baltimore, Md.). 58: 830. PMID 23315750 DOI: 10.1002/Hep.26242  0.316
2013 Chen RC, Naiyanetr P, Shu SA, Wang J, Yang GX, Kenny TP, Guggenheim KC, Butler JD, Bowlus C, Tao MH, Kurth MJ, Ansari AA, Kaplan M, Coppel RL, Lleo A, ... Gershwin ME, et al. Antimitochondrial antibody heterogeneity and the xenobiotic etiology of primary biliary cirrhosis. Hepatology (Baltimore, Md.). 57: 1498-508. PMID 23184636 DOI: 10.1002/Hep.26157  0.751
2013 Dhirapong A, Yang GX, Nadler S, Zhang W, Tsuneyama K, Leung P, Knechtle S, Ansari AA, Coppel RL, Liu FT, He XS, Gershwin ME. Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis. Hepatology (Baltimore, Md.). 57: 708-15. PMID 22996325 DOI: 10.1002/Hep.26067  0.756
2012 Uibo R, Kisand K, Yang CY, Gershwin ME. Primary biliary cirrhosis: a multi-faced interactive disease involving genetics, environment and the immune response. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 120: 857-71. PMID 23009110 DOI: 10.1111/j.1600-0463.2012.02914.x  0.353
2012 Leung PS, Yang GX, Dhirapong A, Tsuneyama K, Ridgway WM, Gershwin ME. Animal models of primary biliary cirrhosis: materials and methods. Methods in Molecular Biology (Clifton, N.J.). 900: 291-316. PMID 22933075 DOI: 10.1007/978-1-60761-720-4_14  0.743
2012 Duarte-Rey C, Bogdanos D, Yang CY, Roberts K, Leung PS, Anaya JM, Worman HJ, Gershwin ME. Primary biliary cirrhosis and the nuclear pore complex. Autoimmunity Reviews. 11: 898-902. PMID 22487189 DOI: 10.1016/J.Autrev.2012.03.005  0.34
2012 Jin Q, Moritoki Y, Lleo A, Tsuneyama K, Invernizzi P, Moritoki H, Kikuchi K, Lian ZX, Hirschfield GM, Ansari AA, Coppel RL, Gershwin ME, Niu J. Comparative analysis of portal cell infiltrates in antimitochondrial autoantibody-positive versus antimitochondrial autoantibody-negative primary biliary cirrhosis. Hepatology (Baltimore, Md.). 55: 1495-506. PMID 22135136 DOI: 10.1002/Hep.25511  0.328
2011 Ambrosini YM, Yang GX, Zhang W, Tsuda M, Shu S, Tsuneyama K, Leung PS, Ansari AA, Coppel RL, Gershwin ME. The multi-hit hypothesis of primary biliary cirrhosis: polyinosinic-polycytidylic acid (poly I:C) and murine autoimmune cholangitis. Clinical and Experimental Immunology. 166: 110-20. PMID 21910728 DOI: 10.1111/J.1365-2249.2011.04453.X  0.764
2011 Naiyanetr P, Butler JD, Meng L, Pfeiff J, Kenny TP, Guggenheim KG, Reiger R, Lam K, Kurth MJ, Ansari AA, Coppel RL, López-Hoyos M, Gershwin ME, Leung PS. Electrophile-modified lipoic derivatives of PDC-E2 elicits anti-mitochondrial antibody reactivity. Journal of Autoimmunity. 37: 209-16. PMID 21763105 DOI: 10.1016/J.Jaut.2011.06.001  0.753
2011 Tsuda M, Ambrosini YM, Zhang W, Yang GX, Ando Y, Rong G, Tsuneyama K, Sumida K, Shimoda S, Bowlus CL, Leung PS, He XS, Coppel RL, Ansari AA, Lian ZX, ... Gershwin ME, et al. Fine phenotypic and functional characterization of effector cluster of differentiation 8 positive T cells in human patients with primary biliary cirrhosis. Hepatology (Baltimore, Md.). 54: 1293-302. PMID 21735469 DOI: 10.1002/Hep.24526  0.702
2011 Selmi C, Bowlus CL, Gershwin ME, Coppel RL. Primary biliary cirrhosis. Lancet (London, England). 377: 1600-9. PMID 21529926 DOI: 10.1016/S0140-6736(10)61965-4  0.316
2011 Rong G, Zhong R, Lleo A, Leung PS, Bowlus CL, Yang GX, Yang CY, Coppel RL, Ansari AA, Cuebas DA, Worman HJ, Invernizzi P, Gores GJ, Norman G, He XS, ... Gershwin ME, et al. Epithelial cell specificity and apotope recognition by serum autoantibodies in primary biliary cirrhosis. Hepatology (Baltimore, Md.). 54: 196-203. PMID 21488079 DOI: 10.1002/Hep.24355  0.312
2011 Dhirapong A, Lleo A, Yang GX, Tsuneyama K, Dunn R, Kehry M, Packard TA, Cambier JC, Liu FT, Lindor K, Coppel RL, Ansari AA, Gershwin ME. B cell depletion therapy exacerbates murine primary biliary cirrhosis Hepatology. 53: 527-535. PMID 21274873 DOI: 10.1002/Hep.24044  0.754
2011 Ishibashi H, Komori A, Shimoda S, Ambrosini YM, Gershwin ME, Nakamura M. Risk factors and prediction of long-term outcome in primary biliary cirrhosis. Internal Medicine (Tokyo, Japan). 50: 1-10. PMID 21212566 DOI: 10.2169/Internalmedicine.50.4462  0.702
2010 Li M, Abraham NG, Vanella L, Zhang Y, Inaba M, Hosaka N, Hoshino S, Shi M, Ambrosini YM, Gershwin ME, Ikehara S. Successful modulation of type 2 diabetes in db/db mice with intra-bone marrow--bone marrow transplantation plus concurrent thymic transplantation. Journal of Autoimmunity. 35: 414-23. PMID 20884174 DOI: 10.1016/J.Jaut.2010.09.001  0.679
2010 Tsuda M, Torgerson TR, Selmi C, Gambineri E, Carneiro-Sampaio M, Mannurita SC, Leung PS, Norman GL, Gershwin ME. The spectrum of autoantibodies in IPEX syndrome is broad and includes anti-mitochondrial autoantibodies. Journal of Autoimmunity. 35: 265-8. PMID 20650610 DOI: 10.1016/j.jaut.2010.06.017  0.335
2010 Selmi C, Gershwin ME. The etiology mystery in primary biliary cirrhosis. Digestive Diseases (Basel, Switzerland). 28: 105-15. PMID 20460898 DOI: 10.1159/000282073  0.312
2010 Invernizzi P, Selmi C, Gershwin ME. Update on primary biliary cirrhosis. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 42: 401-8. PMID 20359968 DOI: 10.1016/j.dld.2010.02.014  0.332
2010 Ueno Y, Ambrosini YM, Moritoki Y, Ridgway WM, Gershwin ME. Murine models of autoimmune cholangitis. Current Opinion in Gastroenterology. 26: 274-9. PMID 20224397 DOI: 10.1097/Mog.0B013E32833755Aa  0.71
2009 Selmi C, Meda F, Kasangian A, Invernizzi P, Tian Z, Lian Z, Podda M, Gershwin ME. Experimental evidence on the immunopathogenesis of primary biliary cirrhosis. Cellular & Molecular Immunology. 7: 1-10. PMID 20029462 DOI: 10.1038/cmi.2009.104  0.322
2009 Selmi C, Lleo A, Pasini S, Zuin M, Gershwin ME. Innate immunity and primary biliary cirrhosis. Current Molecular Medicine. 9: 45-51. PMID 19199941 DOI: 10.2174/156652409787314525  0.306
2009 Lleo A, Selmi C, Invernizzi P, Podda M, Coppel RL, Mackay IR, Gores GJ, Ansari AA, Van de Water J, Gershwin ME. Apotopes and the biliary specificity of primary biliary cirrhosis. Hepatology (Baltimore, Md.). 49: 871-9. PMID 19185000 DOI: 10.1002/Hep.22736  0.363
2009 Dhirapong A, Lleo A, Leung P, Gershwin ME, Liu FT. The immunological potential of galectin-1 and -3. Autoimmunity Reviews. 8: 360-3. PMID 19064001 DOI: 10.1016/J.Autrev.2008.11.009  0.737
2009 Selmi C, Cocchi CA, Zuin M, Gershwin ME. The chemical pathway to primary biliary cirrhosis. Clinical Reviews in Allergy & Immunology. 36: 23-9. PMID 18509764 DOI: 10.1007/s12016-008-8089-7  0.315
2008 Gershwin ME, Mackay IR. The causes of primary biliary cirrhosis: Convenient and inconvenient truths. Hepatology (Baltimore, Md.). 47: 737-45. PMID 18098322 DOI: 10.1002/hep.22042  0.399
2007 Oertelt S, Ridgway WM, Ansari AA, Coppel RL, Gershwin ME. Murine models of primary biliary cirrhosis: Comparisons and contrasts. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 37: S365-9. PMID 17931188 DOI: 10.1111/J.1872-034X.2007.00226.X  0.319
2007 Leung PS, Park O, Tsuneyama K, Kurth MJ, Lam KS, Ansari AA, Coppel RL, Gershwin ME. Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization. Journal of Immunology (Baltimore, Md. : 1950). 179: 2651-7. PMID 17675529 DOI: 10.4049/Jimmunol.179.4.2651  0.326
2007 Bellucci R, Oertelt S, Gallagher M, Li S, Zorn E, Weller E, Porcheray F, Alyea EP, Soiffer RJ, Munshi NC, Gershwin ME, Ritz J. Differential epitope mapping of antibodies to PDC-E2 in patients with hematologic malignancies after allogeneic hematopoietic stem cell transplantation and primary biliary cirrhosis. Blood. 109: 2001-7. PMID 17068145 DOI: 10.1182/blood-2006-06-030304  0.316
2006 Miyakawa H, Tanaka A, Selmi C, Hosoya N, Mataki N, Kikuchi K, Kato T, Arai J, Goto T, Gershwin ME. Serum reactivity against bacterial pyruvate dehydrogenase: increasing the specificity of anti-mitochondrial antibodies for the diagnosis of primary biliary cirrhosis. Clinical & Developmental Immunology. 13: 289-94. PMID 17162370 DOI: 10.1080/17402520600668706  0.305
2005 Leung PS, Coppel RL, Gershwin ME. Etiology of primary biliary cirrhosis: the search for the culprit. Seminars in Liver Disease. 25: 327-36. PMID 16143948 DOI: 10.1055/S-2005-916324  0.302
2005 Ichiki Y, Leung PS, Ishibashi H, Coppel RL, Ansari AA, Gershwin ME. Mitochondria and autoimmunity in primary biliary cirrhosis. Mitochondrion. 4: 743-53. PMID 16120429 DOI: 10.1016/J.Mito.2004.07.024  0.39
2005 Wu CT, Davis PA, Luketic VA, Gershwin ME. A review of the physiological and immunological functions of biliary epithelial cells: targets for primary biliary cirrhosis, primary sclerosing cholangitis and drug-induced ductopenias. Clinical & Developmental Immunology. 11: 205-13. PMID 15559365 DOI: 10.1080/17402520400004177  0.305
2005 Lan RY, Leung P, Ansari AA, Coppel RL, Gershwin ME. Solving the primary biliary cirrhosis puzzle: The emerging image of immunopathology in primary biliary cirrhosis Clinical and Applied Immunology Reviews. 5: 271-284. DOI: 10.1016/J.Cair.2005.07.001  0.409
2004 Mao TK, Davis PA, Odin JA, Coppel RL, Gershwin ME. Sidechain biology and the immunogenicity of PDC-E2, the major autoantigen of primary biliary cirrhosis. Hepatology (Baltimore, Md.). 40: 1241-8. PMID 15558739 DOI: 10.1002/HEP.20491  0.325
2004 Kita H, Nalbandian G, Keeffe EB, Coppel RL, Gershwin ME. Pathogenesis of primary biliary cirrhosis. Clinics in Liver Disease. 7: 821-39. PMID 14598794 DOI: 10.1016/S1089-3261(03)00096-5  0.313
2003 Bruggraber SF, Leung PS, Amano K, Quan C, Kurth MJ, Nantz MH, Benson GD, Van de Water J, Luketic V, Roche TE, Ansari AA, Coppel RL, Gershwin ME. Autoreactivity to lipoate and a conjugated form of lipoate in primary biliary cirrhosis. Gastroenterology. 125: 1705-13. PMID 14724823 DOI: 10.1053/J.Gastro.2003.09.034  0.311
2003 Leung PS, Quan C, Park O, Van de Water J, Kurth MJ, Nantz MH, Ansari AA, Coppel RL, Lam KS, Gershwin ME. Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies. Journal of Immunology (Baltimore, Md. : 1950). 170: 5326-32. PMID 12734383 DOI: 10.4049/Jimmunol.170.10.5326  0.337
2003 Fukushima N, Nalbandian G, Van De Water J, White K, Ansari AA, Leung P, Kenny T, Kamita SG, Hammock BD, Coppel RL, Stevenson F, Ishibashi H, Gershwin ME. Characterization of recombinant monoclonal IgA anti-PDC-E2 autoantibodies derived from patients with PBC. Hepatology (Baltimore, Md.). 36: 1383-92. PMID 12447863 DOI: 10.1053/Jhep.2002.37140  0.39
2002 Nishio A, Keeffe EB, Gershwin ME. Immunopathogenesis of primary biliary cirrhosis. Seminars in Liver Disease. 22: 291-302. PMID 12360422 DOI: 10.1055/S-2002-34506  0.402
2002 Nishio A, Keeffe EB, Gershwin ME. Primary biliary cirrhosis: lessons learned from an organ-specific disease. Clinical and Experimental Medicine. 1: 165-78. PMID 11918275 DOI: 10.1007/s102380100000  0.365
2002 He XS, Ansari AA, Gershwin ME. Xenobiotic considerations for the development of autoimmune liver diseases: bad genes and bad luck. Reviews On Environmental Health. 16: 191-202. PMID 11765908 DOI: 10.1515/REVEH.2001.16.3.191  0.316
2001 Sasaki M, Van De Water J, Kenny TP, Gallo ML, Leung PSC, Nakanuma Y, Ansari AA, Coppel RL, Neuberger J, Gershwin ME. Immunoglobulin gene usage and immunohistochemical characteristics of human monoclonal antibodies to the mitochondrial autoantigens of primary biliary cirrhosis induced in the XenoMouse Hepatology. 34: 631-637. PMID 11584357 DOI: 10.1053/Jhep.2001.27544  0.323
2001 Migliaccio C, Van de Water J, Ansari AA, Kaplan MM, Coppel RL, Lam KS, Thompson RK, Stevenson F, Gershwin ME. Heterogeneous response of antimitochondrial autoantibodies and bile duct apical staining monoclonal antibodies to pyruvate dehydrogenase complex E2: the molecule versus the mimic. Hepatology (Baltimore, Md.). 33: 792-801. PMID 11283841 DOI: 10.1053/Jhep.2001.23783  0.337
2000 Nishio A, Coppel R, Ishibashi H, Gershwin ME. The pyruvate dehydrogenase complex as a target autoantigen in primary biliary cirrhosis. Bailliere's Best Practice & Research. Clinical Gastroenterology. 14: 535-47. PMID 10976013 DOI: 10.1053/BEGA.2000.0102  0.377
2000 Mackay IR, Whittingham S, Fida S, Myers M, Ikuno N, Gershwin ME, Rowley MJ. The peculiar autoimmunity of primary biliary cirrhosis. Immunological Reviews. 174: 226-37. PMID 10807519 DOI: 10.1034/J.1600-0528.2002.017410.X  0.315
2000 Gershwin ME, Ansari AA, Mackay IR, Nakanuma Y, Nishio A, Rowley MJ, Coppel RL. Primary biliary cirrhosis: an orchestrated immune response against epithelial cells. Immunological Reviews. 174: 210-25. PMID 10807518 DOI: 10.1034/J.1600-0528.2002.017402.X  0.403
2000 Tsuneyama K, Saito K, Ruebner BH, Konishi I, Nakanuma Y, Gershwin ME. Immunological similarities between primary sclerosing cholangitis and chronic sclerosing sialadenitis: report of the overlapping of these two autoimmune diseases. Digestive Diseases and Sciences. 45: 366-72. PMID 10711453 DOI: 10.1023/A:1005429130150  0.301
2000 Reynoso-Paz S, Leung PS, Van De Water J, Tanaka A, Munoz S, Bass N, Lindor K, Donald PJ, Coppel RL, Ansari AA, Gershwin ME. Evidence for a locally driven mucosal response and the presence of mitochondrial antigens in saliva in primary biliary cirrhosis. Hepatology (Baltimore, Md.). 31: 24-9. PMID 10613723 DOI: 10.1002/Hep.510310106  0.323
1999 Reynoso-Paz S, Coppel RL, Mackay IR, Bass NM, Ansari AA, Gershwin ME. The immunobiology of bile and biliary epithelium. Hepatology (Baltimore, Md.). 30: 351-7. PMID 10421640 DOI: 10.1002/Hep.510300218  0.303
1997 Mattalia A, Lüttig B, Rosina F, Leung PS, Van de Water J, Bauducci M, Ciancio A, Böker KH, Worman H, Cooper RL, Manns M, Ansari A, Rizzetto M, Gershwin ME. Persistence of autoantibodies against recombinant mitochondrial and nuclear pore proteins after orthotopic liver transplantation for primary biliary cirrhosis. Journal of Autoimmunity. 10: 491-7. PMID 9376077 DOI: 10.1006/Jaut.1997.0156  0.327
1997 Van de Water J, Shimoda S, Niho Y, Coppel R, Ansari A, Gershwin ME. The role of T cells in primary biliary cirrhosis. Seminars in Liver Disease. 17: 105-13. PMID 9170197 DOI: 10.1055/S-2007-1007188  0.332
1997 Joplin R, Gershwin ME. Ductular expression of autoantigens in primary biliary cirrhosis. Seminars in Liver Disease. 17: 97-103. PMID 9170196 DOI: 10.1055/s-2007-1007187  0.314
1997 Nishio A, Van De Water J, Leung PSC, Joplin R, Neuberger JM, Lake J, Björkland A, Tötterman TH, Peters M, Worman HJ, Ansari AA, Coppel RL, Gershwin ME. Comparative studies of antimitochondrial autoantibodies in sera and bile in primary biliary cirrhosis Hepatology. 25: 1085-1089. PMID 9141421  0.334
1997 Leung PS, Cha S, Joplin RE, Galperin C, Van de Water J, Ansari AA, Coppel RL, Schatz PJ, Cwirla S, Fabris LE, Neuberger JM, Gershwin ME. Inhibition of PDC-E2 human combinatorial autoantibodies by peptide mimotopes. Journal of Autoimmunity. 9: 785-93. PMID 9115581 DOI: 10.1006/Jaut.1996.0101  0.306
1997 Leung PS, Coppel RL, Ansari A, Munoz S, Gershwin ME. Antimitochondrial antibodies in primary biliary cirrhosis. Seminars in Liver Disease. 17: 61-9. PMID 9089911 DOI: 10.1055/S-2007-1007183  0.344
1997 Yip TT, Van de Water J, Gershwin ME, Coppel RL, Hutchens TW. Cryptic antigenic determinants on the extracellular pyruvate dehydrogenase complex/mimeotope found in primary biliary cirrhosis. A probe by affinity mass spectrometry. The Journal of Biological Chemistry. 271: 32825-33. PMID 8955120 DOI: 10.1074/jbc.271.51.32825  0.349
1997 Galperin C, Gershwin ME. Immunopathology of primary biliary cirrhosis. Bailliere's Clinical Gastroenterology. 10: 461-81. PMID 8905119 DOI: 10.1016/S0950-3528(96)90053-6  0.308
1996 Leung PS, Van de Water J, Coppel RL, Nakanuma Y, Munoz S, Gershwin ME. Molecular aspects and the pathological basis of primary biliary cirrhosis. Journal of Autoimmunity. 9: 119-28. PMID 8738955 DOI: 10.1006/jaut.1996.0015  0.353
1995 Coppel RL, Gershwin ME. Primary biliary cirrhosis: the molecule and the mimic. Immunological Reviews. 144: 17-49. PMID 7590813 DOI: 10.1111/j.1600-065X.1995.tb00064.x  0.338
1995 Leung PSC, Chuang DT, Wynn RM, Cha S, Danner DJ, Ansari A, Coppel RL, Gershwin ME. Autoantibodies to BCOADC-E2 in patients with primary biliary cirrhosis recognize a conformational epitope Hepatology. 22: 505-513. PMID 7543435 DOI: 10.1016/0270-9139(95)90572-3  0.329
1994 Tsuneyama K, Van de Water J, Nakanuma Y, Cha S, Ansari A, Coppel R, Gershwin ME. Human combinatorial autoantibodies and mouse monoclonal antibodies to PDC-E2 produce abnormal apical staining of salivary glands in patients with coexistent primary biliary cirrhosis and Sjögren's syndrome. Hepatology (Baltimore, Md.). 20: 893-8. PMID 7927231 DOI: 10.1002/Hep.1840200418  0.305
1994 Cha S, Leung PSC, Coppel RL, Van De Water J, Ansari AA, Gershwin ME. Heterogeneity of combinatorial human autoantibodies against PDC-E2 and biliary epithelial cells in patients with primary biliary cirrhosis Hepatology. 20: 574-583. DOI: 10.1002/Hep.1840200305  0.341
1993 Van de Water J, Turchany J, Leung PS, Lake J, Munoz S, Surh CD, Coppel R, Ansari A, Nakanuma Y, Gershwin ME. Molecular mimicry in primary biliary cirrhosis. Evidence for biliary epithelial expression of a molecule cross-reactive with pyruvate dehydrogenase complex-E2. The Journal of Clinical Investigation. 91: 2653-64. PMID 8514873 DOI: 10.1172/JCI116504  0.354
1993 Cha S, Leung PS, Gershwin ME, Fletcher MP, Ansari AA, Coppel RL. Combinatorial autoantibodies to dihydrolipoamide acetyltransferase, the major autoantigen of primary biliary cirrhosis. Proceedings of the National Academy of Sciences of the United States of America. 90: 2527-31. PMID 8460168 DOI: 10.1073/pnas.90.6.2527  0.333
1990 Mackay IR, Gershwin ME. Molecular basis of mitochondrial autoreactivity in primary biliary cirrhosis. Immunology Today. 10: 315-8. PMID 2480138 DOI: 10.1016/0167-5699(89)90088-1  0.308
1990 Robertson CA, Coppel RL, Prindiville T, Fregeau D, Kaplan M, Dickson ER, Gershwin ME. The relative affinity of recombinant dihydrolipoamide transacetylase for autoantibodies in primary biliary cirrhosis Hepatology. 11: 717-722. PMID 2347544 DOI: 10.1002/hep.1840110502  0.311
1990 Krams SM, Van de Water J, Coppel RL, Esquivel C, Roberts J, Ansari A, Gershwin ME. Analysis of hepatic T lymphocyte and immunoglobulin deposits in patients with primary biliary cirrhosis. Hepatology (Baltimore, Md.). 12: 306-13. PMID 2202637 DOI: 10.1002/Hep.1840120219  0.36
1989 Mackay IR, Gershwin ME. Primary biliary cirrhosis: current knowledge, perspectives, and future directions. Seminars in Liver Disease. 9: 149-57. PMID 2658106 DOI: 10.1055/s-2008-1040507  0.362
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