| Year |
Citation |
Score |
| 2024 |
Hsu BY, Driscoll J, Tateno C, Mattis AN, Kelley RK, Willenbring H. Human Hepatocytes Can Give Rise To Intrahepatic Cholangiocarcinomas. Gastroenterology. PMID 38866344 DOI: 10.1053/j.gastro.2024.05.033 |
0.633 |
|
| 2021 |
Laemmle A, Poms M, Hsu B, Borsuk M, Rüfenacht V, Robinson J, Sadowski MC, Nuoffer JM, Häberle J, Willenbring H. Aquaporin 9 Induction in Human iPSC-derived Hepatocytes Facilitates Modeling of Ornithine Transcarbamylase Deficiency. Hepatology (Baltimore, Md.). PMID 34786702 DOI: 10.1002/hep.32247 |
0.409 |
|
| 2021 |
Lee-Montiel FT, Laemmle A, Charwat V, Dumont L, Lee CS, Huebsch N, Okochi H, Hancock MJ, Siemons B, Boggess SC, Goswami I, Miller EW, Willenbring H, Healy KE. Integrated Isogenic Human Induced Pluripotent Stem Cell-Based Liver and Heart Microphysiological Systems Predict Unsafe Drug-Drug Interaction. Frontiers in Pharmacology. 12: 667010. PMID 34025426 DOI: 10.3389/fphar.2021.667010 |
0.304 |
|
| 2021 |
Duwaerts CC, Le Guillou D, Her CL, Phillips NJ, Willenbring H, Mattis AN, Maher JJ. iPSC-derived hepatocytes from patients with nonalcoholic fatty liver disease display a disease-specific gene expression profile. Gastroenterology. PMID 33640436 DOI: 10.1053/j.gastro.2021.02.050 |
0.668 |
|
| 2020 |
Kurial SNT, Willenbring H. Transcriptomic traces of adult human liver progenitor cells. Hepatology (Baltimore, Md.). PMID 31991483 DOI: 10.1002/Hep.31143 |
0.569 |
|
| 2019 |
Chen F, Jimenez RJ, Sharma K, Luu HY, Hsu BY, Ravindranathan A, Stohr BA, Willenbring H. Broad Distribution of Hepatocyte Proliferation in Liver Homeostasis and Regeneration. Cell Stem Cell. PMID 31866223 DOI: 10.1016/J.Stem.2019.11.001 |
0.505 |
|
| 2019 |
Willenbring H, Colnot S. Decision letter: Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts Elife. DOI: 10.7554/Elife.46206.Sa1 |
0.357 |
|
| 2018 |
Huck I, Gunewardena S, Espanol-Suner R, Willenbring H, Apte U. Hepatocyte Nuclear Factor 4 alpha (HNF4α) Activation is Essential for Termination of Liver Regeneration. Hepatology (Baltimore, Md.). PMID 30520062 DOI: 10.1002/Hep.30405 |
0.469 |
|
| 2018 |
Schaub JR, Huppert KA, Kurial SNT, Hsu BY, Cast AE, Donnelly B, Karns RA, Chen F, Rezvani M, Luu HY, Mattis AN, Rougemont AL, Rosenthal P, Huppert SS, Willenbring H. De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation. Nature. PMID 29720662 DOI: 10.1038/S41586-018-0075-5 |
0.731 |
|
| 2016 |
Rezvani M, Español-Suñer R, Malato Y, Dumont L, Grimm AA, Kienle E, Bindman JG, Wiedtke E, Hsu BY, Naqvi SJ, Schwabe RF, Corvera CU, Grimm D, Willenbring H. In Vivo Hepatic Reprogramming of Myofibroblasts with AAV Vectors as a Therapeutic Strategy for Liver Fibrosis. Cell Stem Cell. 18: 809-816. PMID 27257763 DOI: 10.1016/J.Stem.2016.05.005 |
0.546 |
|
| 2016 |
Rezvani M, Grimm AA, Willenbring H. Assessing the therapeutic potential of lab-made hepatocytes. Hepatology (Baltimore, Md.). 64: 287-94. PMID 27014802 DOI: 10.1002/Hep.28569 |
0.549 |
|
| 2016 |
Desai SS, Tung JC, Zhou VX, Grenert JP, Malato Y, Rezvani M, Español-Suñer R, Willenbring H, Weaver VM, Chang TT. Physiological Ranges of Matrix Rigidity Modulate Primary Mouse Hepatocyte Function In Part Through Hepatocyte Nuclear Factor 4 Alpha. Hepatology (Baltimore, Md.). PMID 26755329 DOI: 10.1002/Hep.28450 |
0.444 |
|
| 2015 |
Mattis AN, Song G, Hitchner K, Kim RY, Lee AY, Sharma AD, Malato Y, McManus MT, Esau CC, Koller E, Koliwad S, Lim LP, Maher JJ, Raffai RL, Willenbring H. A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver. Hepatology (Baltimore, Md.). 61: 141-52. PMID 25131933 DOI: 10.1002/Hep.27379 |
0.676 |
|
| 2014 |
Hentzschel F, Hammerschmidt-Kamper C, Börner K, Heiss K, Knapp B, Sattler JM, Kaderali L, Castoldi M, Bindman JG, Malato Y, Willenbring H, Mueller AK, Grimm D. AAV8-mediated in vivo overexpression of miR-155 enhances the protective capacity of genetically attenuated malarial parasites. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 2130-41. PMID 25189739 DOI: 10.1038/Mt.2014.172 |
0.463 |
|
| 2014 |
Schaub JR, Malato Y, Gormond C, Willenbring H. Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury. Cell Reports. 8: 933-9. PMID 25131204 DOI: 10.1016/J.Celrep.2014.07.003 |
0.538 |
|
| 2014 |
Espejel S, Eckardt S, Harbell J, Roll GR, McLaughlin KJ, Willenbring H. Brief report: Parthenogenetic embryonic stem cells are an effective cell source for therapeutic liver repopulation. Stem Cells (Dayton, Ohio). 32: 1983-8. PMID 24740448 DOI: 10.1002/Stem.1726 |
0.539 |
|
| 2014 |
Ng R, Wu H, Xiao H, Chen X, Willenbring H, Steer CJ, Song G. Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia. Hepatology (Baltimore, Md.). 60: 554-64. PMID 24677249 DOI: 10.1002/Hep.27153 |
0.619 |
|
| 2014 |
Zhu S, Rezvani M, Harbell J, Mattis AN, Wolfe AR, Benet LZ, Willenbring H, Ding S. Mouse liver repopulation with hepatocytes generated from human fibroblasts. Nature. 508: 93-7. PMID 24572354 DOI: 10.1038/Nature13020 |
0.747 |
|
| 2014 |
Lim L, Balakrishnan A, Huskey N, Jones KD, Jodari M, Ng R, Song G, Riordan J, Anderton B, Cheung ST, Willenbring H, Dupuy A, Chen X, Brown D, Chang AN, et al. MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer. Hepatology (Baltimore, Md.). 59: 202-15. PMID 23913442 DOI: 10.1002/Hep.26662 |
0.601 |
|
| 2014 |
Schaub JR, Malato Y, Gormond C, Willenbring H. Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury Cell Reports. 8: 933-939. DOI: 10.1016/j.celrep.2014.07.003 |
0.382 |
|
| 2013 |
Mathur A, Loskill P, Hong S, Lee J, Marcus SG, Dumont L, Conklin BR, Willenbring H, Lee LP, Healy KE. Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development. Stem Cell Research & Therapy. 4: S14. PMID 24565415 DOI: 10.1186/Scrt375 |
0.386 |
|
| 2013 |
Willenbring H, Soto-Gutierrez A. Transplantable liver organoids made from only three ingredients. Cell Stem Cell. 13: 139-40. PMID 23910079 DOI: 10.1016/J.Stem.2013.07.014 |
0.535 |
|
| 2013 |
Ma X, Duan Y, Tschudy-Seney B, Roll G, Behbahan IS, Ahuja TP, Tolstikov V, Wang C, McGee J, Khoobyari S, Nolta JA, Willenbring H, Zern MA. Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells. Stem Cells Translational Medicine. 2: 409-19. PMID 23681950 DOI: 10.5966/Sctm.2012-0160 |
0.471 |
|
| 2013 |
Willenbring H, Grompe M. A therapy for liver failure found in the JNK yard. Cell. 153: 283-4. PMID 23582318 DOI: 10.1016/J.Cell.2013.03.033 |
0.504 |
|
| 2013 |
Evert M, Fan B, Malato Y, Ribback S, Dombrowski F, Willenbring H, Chen X, Calvisi D. Akt/Notch activation drives rapid cholangiocarcinoma development originating from mature hepatocytes in the mouse Zeitschrift FüR Gastroenterologie. 51. DOI: 10.1055/S-0032-1332061 |
0.414 |
|
| 2012 |
Fan B, Malato Y, Calvisi DF, Naqvi S, Razumilava N, Ribback S, Gores GJ, Dombrowski F, Evert M, Chen X, Willenbring H. Cholangiocarcinomas can originate from hepatocytes in mice. The Journal of Clinical Investigation. 122: 2911-5. PMID 22797301 DOI: 10.1172/Jci63212 |
0.566 |
|
| 2012 |
Mattis AN, Willenbring H. A ZFN/piggyBac step closer to autologous liver cell therapy. Hepatology (Baltimore, Md.). 55: 2033-5. PMID 22422378 DOI: 10.1002/Hep.25715 |
0.705 |
|
| 2012 |
Ng R, Song G, Roll GR, Frandsen NM, Willenbring H. A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration. The Journal of Clinical Investigation. 122: 1097-108. PMID 22326957 DOI: 10.1172/Jci46039 |
0.583 |
|
| 2012 |
Rountree CB, Mishra L, Willenbring H. Stem cells in liver diseases and cancer: recent advances on the path to new therapies. Hepatology (Baltimore, Md.). 55: 298-306. PMID 22030746 DOI: 10.1002/Hep.24762 |
0.536 |
|
| 2011 |
Malato Y, Naqvi S, Schürmann N, Ng R, Wang B, Zape J, Kay MA, Grimm D, Willenbring H. Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. The Journal of Clinical Investigation. 121: 4850-60. PMID 22105172 DOI: 10.1172/Jci59261 |
0.679 |
|
| 2011 |
Willenbring H. A simple code for installing hepatocyte function. Cell Stem Cell. 9: 89-91. PMID 21816357 DOI: 10.1016/J.Stem.2011.07.009 |
0.333 |
|
| 2011 |
Eckardt S, McLaughlin KJ, Willenbring H. Mouse chimeras as a system to investigate development, cell and tissue function, disease mechanisms and organ regeneration. Cell Cycle (Georgetown, Tex.). 10: 2091-9. PMID 21606677 DOI: 10.4161/Cc.10.13.16360 |
0.366 |
|
| 2011 |
D'Alessio JA, Ng R, Willenbring H, Tjian R. Core promoter recognition complex changes accompany liver development. Proceedings of the National Academy of Sciences of the United States of America. 108: 3906-11. PMID 21368148 DOI: 10.1073/Pnas.1100640108 |
0.576 |
|
| 2010 |
Malato Y, Willenbring H. The MAP3K TAK1: a chock block to liver cancer formation. Hepatology (Baltimore, Md.). 52: 1506-9. PMID 20879030 DOI: 10.1002/hep.23878 |
0.317 |
|
| 2010 |
Roll GR, Willenbring H. Transplanted nonviable human hepatocytes produce appreciable serum albumin levels in mice. Stem Cell Research. 5: 267-70. PMID 20829142 DOI: 10.1016/J.Scr.2010.07.004 |
0.447 |
|
| 2010 |
Espejel S, Roll GR, McLaughlin KJ, Lee AY, Zhang JY, Laird DJ, Okita K, Yamanaka S, Willenbring H. Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice. The Journal of Clinical Investigation. 120: 3120-6. PMID 20739754 DOI: 10.1172/Jci43267 |
0.537 |
|
| 2010 |
Erker L, Azuma H, Lee AY, Guo C, Orloff S, Eaton L, Benedetti E, Jensen B, Finegold M, Willenbring H, Grompe M. Therapeutic liver reconstitution with murine cells isolated long after death. Gastroenterology. 139: 1019-29. PMID 20621682 DOI: 10.1053/J.Gastro.2010.05.082 |
0.478 |
|
| 2010 |
Song G, Sharma AD, Roll GR, Ng R, Lee AY, Blelloch RH, Frandsen NM, Willenbring H. MicroRNAs control hepatocyte proliferation during liver regeneration. Hepatology (Baltimore, Md.). 51: 1735-43. PMID 20432256 DOI: 10.1002/Hep.23547 |
0.598 |
|
| 2008 |
Mitchell C, Willenbring H. A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice. Nature Protocols. 3: 1167-70. PMID 18600221 DOI: 10.1038/Nprot.2008.80 |
0.435 |
|
| 2008 |
Willenbring H, Sharma AD, Vogel A, Lee AY, Rothfuss A, Wang Z, Finegold M, Grompe M. Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis. Cancer Cell. 14: 59-67. PMID 18598944 DOI: 10.1016/J.Ccr.2008.05.004 |
0.384 |
|
| 2007 |
Ramalho-Santos M, Willenbring H. On the origin of the term "stem cell". Cell Stem Cell. 1: 35-8. PMID 18371332 DOI: 10.1016/J.Stem.2007.05.013 |
0.325 |
|
| 2006 |
Bailey AS, Willenbring H, Jiang S, Anderson DA, Schroeder DA, Wong MH, Grompe M, Fleming WH. Myeloid lineage progenitors give rise to vascular endothelium. Proceedings of the National Academy of Sciences of the United States of America. 103: 13156-61. PMID 16920790 DOI: 10.1073/Pnas.0604203103 |
0.316 |
|
| 2006 |
Rizvi AZ, Swain JR, Davies PS, Bailey AS, Decker AD, Willenbring H, Grompe M, Fleming WH, Wong MH. Bone marrow-derived cells fuse with normal and transformed intestinal stem cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 6321-5. PMID 16606845 DOI: 10.1073/Pnas.0508593103 |
0.363 |
|
| 2006 |
Vogel A, Aslan JE, Willenbring H, Klein C, Finegold M, Mount H, Thomas G, Grompe M. Sustained phosphorylation of Bid is a marker for resistance to Fas-induced apoptosis during chronic liver diseases. Gastroenterology. 130: 104-19. PMID 16401474 DOI: 10.1053/J.Gastro.2005.10.012 |
0.41 |
|
| 2006 |
Held PK, Al-Dhalimy M, Willenbring H, Akkari Y, Jiang S, Torimaru Y, Olson S, Fleming WH, Finegold M, Grompe M. In vivo genetic selection of renal proximal tubules. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 49-58. PMID 16216560 DOI: 10.1016/J.Ymthe.2005.09.004 |
0.392 |
|
| 2005 |
Bailey AS, Willenbring H, Jiang S, Schroeder DA, Anderson DA, Grompe M, Wong MH, Fleming WH. Myeloid Lineage-Restricted Progenitors Contribute to Vascular Endothelium. Blood. 106: 2267-2267. DOI: 10.1182/Blood.V106.11.2267.2267 |
0.374 |
|
| 2004 |
Willenbring H, Grompe M. Delineating the hepatocyte's hematopoietic fusion partner. Cell Cycle (Georgetown, Tex.). 3: 1489-91. PMID 15611666 DOI: 10.4161/Cc.3.12.1304 |
0.388 |
|
| 2004 |
Willenbring H, Bailey AS, Foster M, Akkari Y, Dorrell C, Olson S, Finegold M, Fleming WH, Grompe M. Myelomonocytic cells are sufficient for therapeutic cell fusion in liver. Nature Medicine. 10: 744-8. PMID 15195088 DOI: 10.1038/Nm1062 |
0.459 |
|
| 2003 |
Willenbring H, Grompe M. Embryonic versus adult stem cell pluripotency: in liver only fusion matters. Journal of Assisted Reproduction and Genetics. 20: 393-4. PMID 14649377 DOI: 10.1023/A:1026233224751 |
0.468 |
|
| 2003 |
Wang X, Willenbring H, Akkari Y, Torimaru Y, Foster M, Al-Dhalimy M, Lagasse E, Finegold M, Olson S, Grompe M. Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature. 422: 897-901. PMID 12665832 DOI: 10.1038/Nature01531 |
0.447 |
|
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