Joseph H. Nadeau - Publications

Case Western Reserve University, Cleveland Heights, OH, United States 
Genetics, Oncology, Molecular Biology

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Riordan JD, Nadeau JH. From Peas to Disease: Modifier Genes, Network Resilience, and the Genetics of Health. American Journal of Human Genetics. 101: 177-191. PMID 28777930 DOI: 10.1016/J.Ajhg.2017.06.004  0.319
2017 Schlecht SH, Smith LM, Ramcharan MA, Bigelow EM, Nolan BT, Mathis NJ, Cathey A, Manley E, Menon R, McEachin RC, Nadeau JH, Jepsen KJ. Canalization leads to similar whole bone mechanical function at maturity in two inbred strains of mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28177139 DOI: 10.1002/Jbmr.3093  0.3
2017 Attie AD, Churchill GA, Nadeau JH. How mice are indispensable for understanding obesity and diabetes genetics. Current Opinion in Endocrinology, Diabetes, and Obesity. 24: 83-91. PMID 28107248 DOI: 10.1097/Med.0000000000000321  0.379
2016 Doerner SK, Reiss ES, Leung ES, Ko JS, Heaney JD, Berger NA, Lambris JD, Nadeau JH. High-fat diet-induced complement activation mediates intestinal inflammation and neoplasia, independent of obesity. Molecular Cancer Research : McR. PMID 27535705 DOI: 10.1158/1541-7786.Mcr-16-0153  0.341
2016 Sinasac DS, Riordan JD, Spiezio SH, Yandell BS, Croniger CM, Nadeau JH. Genetic control of obesity, glucose homeostasis, dyslipidemia and fatty liver in a mouse model of diet-induced metabolic syndrome. International Journal of Obesity (2005). 40: 346-55. PMID 26381349 DOI: 10.1038/Ijo.2015.184  0.472
2016 Sinasac DS, Riordan JD, Spiezio SH, Yandell BS, Croniger CM, Nadeau JH. Genetic control of obesity, glucose homeostasis, dyslipidemia and fatty liver in a mouse model of diet-induced metabolic syndrome International Journal of Obesity. 40: 346-355. DOI: 10.1038/ijo.2015.184  0.408
2015 Buchner DA, Nadeau JH. Contrasting genetic architectures in different mouse reference populations used for studying complex traits. Genome Research. 25: 775-91. PMID 25953951 DOI: 10.1101/Gr.187450.114  0.319
2014 Nakouzi GA, Nadeau JH. Does dietary folic acid supplementation in mouse NTD models affect neural tube development or gamete preference at fertilization? Bmc Genetics. 15: 91. PMID 25154628 DOI: 10.1186/S12863-014-0091-X  0.341
2014 Spiezio SH, Amon LM, McMillen TS, Vick CM, Houston BA, Caldwell M, Ogimoto K, Morton GJ, Kirk EA, Schwartz MW, Nadeau JH, LeBoeuf RC. Genetic determinants of atherosclerosis, obesity, and energy balance in consomic mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 25: 549-63. PMID 25001233 DOI: 10.1007/S00335-014-9530-2  0.358
2014 Cannon MV, Buchner DA, Hester J, Miller H, Sehayek E, Nadeau JH, Serre D. Maternal nutrition induces pervasive gene expression changes but no detectable DNA methylation differences in the liver of adult offspring. Plos One. 9: e90335. PMID 24594983 DOI: 10.1371/Journal.Pone.0090335  0.355
2013 Lehoczky JA, Thomas PE, Patrie KM, Owens KM, Villarreal LM, Galbraith K, Washburn J, Johnson CN, Gavino B, Borowsky AD, Millen KJ, Wakenight P, Law W, Van Keuren ML, Gavrilina G, ... ... Nadeau JH, et al. A novel intergenic ETnII-β insertion mutation causes multiple malformations in polypodia mice. Plos Genetics. 9: e1003967. PMID 24339789 DOI: 10.1371/Journal.Pgen.1003967  0.304
2013 Zechel JL, Doerner SK, Lager A, Tesar PJ, Heaney JD, Nadeau JH. Contrasting effects of Deadend1 (Dnd1) gain and loss of function mutations on allelic inheritance, testicular cancer, and intestinal polyposis. Bmc Genetics. 14: 54. PMID 23773267 DOI: 10.1186/1471-2156-14-54  0.333
2013 DeSantis DA, Lee P, Doerner SK, Ko CW, Kawasoe JH, Hill-Baskin AE, Ernest SR, Bhargava P, Hur KY, Cresci GA, Pritchard MT, Lee CH, Nagy LE, Nadeau JH, Croniger CM. Genetic resistance to liver fibrosis on A/J mouse chromosome 17. Alcoholism, Clinical and Experimental Research. 37: 1668-79. PMID 23763294 DOI: 10.1111/Acer.12157  0.777
2012 Nadeau JH, Forejt J, Takada T, Shiroishi T. Chromosome substitution strains: gene discovery, functional analysis, and systems studies. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 693-705. PMID 22961226 DOI: 10.1007/s00335-012-9426-y  0.402
2012 Nelson VR, Heaney JD, Tesar PJ, Davidson NO, Nadeau JH. Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability. Proceedings of the National Academy of Sciences of the United States of America. 109: E2766-73. PMID 22923694 DOI: 10.1073/Pnas.1207169109  0.423
2012 Buchner DA, Geisinger JM, Glazebrook PA, Morgan MG, Spiezio SH, Kaiyala KJ, Schwartz MW, Sakurai T, Furley AJ, Kunze DL, Croniger CM, Nadeau JH. The juxtaparanodal proteins CNTNAP2 and TAG1 regulate diet-induced obesity. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 431-42. PMID 22752552 DOI: 10.1007/S00335-012-9400-8  0.397
2012 Spiezio SH, Takada T, Shiroishi T, Nadeau JH. Genetic divergence and the genetic architecture of complex traits in chromosome substitution strains of mice. Bmc Genetics. 13: 38. PMID 22606935 DOI: 10.1186/1471-2156-13-38  0.485
2012 Heaney JD, Anderson EL, Michelson MV, Zechel JL, Conrad PA, Page DC, Nadeau JH. Germ cell pluripotency, premature differentiation and susceptibility to testicular teratomas in mice. Development (Cambridge, England). 139: 1577-86. PMID 22438569 DOI: 10.1242/Dev.076851  0.336
2011 Zechel JL, MacLennan GT, Heaney JD, Nadeau JH. Spontaneous metastasis in mouse models of testicular germ-cell tumours. International Journal of Andrology. 34: e278-87. PMID 21651572 DOI: 10.1111/J.1365-2605.2011.01160.X  0.332
2011 Yazbek SN, Buchner DA, Geisinger JM, Burrage LC, Spiezio SH, Zentner GE, Hsieh CW, Scacheri PC, Croniger CM, Nadeau JH. Deep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasis. Genome Research. 21: 1065-73. PMID 21507882 DOI: 10.1101/Gr.120741.111  0.72
2011 Nadeau JH, Dudley AM. Genetics. Systems genetics. Science (New York, N.Y.). 331: 1015-6. PMID 21350153 DOI: 10.1126/Science.1203869  0.329
2011 Cook MS, Munger SC, Nadeau JH, Cape B. Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background Development. 138: 23-32. PMID 21115610 DOI: 10.1242/Jcs.084921  0.331
2011 Buchner DA, Yazbek SN, Solinas P, Burrage LC, Morgan MG, Hoppel CL, Nadeau JH. Increased mitochondrial oxidative phosphorylation in the liver is associated with obesity and insulin resistance. Obesity (Silver Spring, Md.). 19: 917-24. PMID 20885388 DOI: 10.1038/Oby.2010.214  0.654
2010 Nelson VR, Nadeau JH. Transgenerational genetic effects. Epigenomics. 2: 797-806. PMID 22122083 DOI: 10.2217/Epi.10.57  0.407
2010 Nelson VR, Spiezio SH, Nadeau JH. Transgenerational genetic effects of the paternal Y chromosome on daughters' phenotypes. Epigenomics. 2: 513-21. PMID 22121971 DOI: 10.2217/Epi.10.26  0.442
2010 Gray JD, Nakouzi G, Slowinska-Castaldo B, Dazard JE, Rao JS, Nadeau JH, Ross ME. Functional interactions between the LRP6 WNT co-receptor and folate supplementation. Human Molecular Genetics. 19: 4560-72. PMID 20843827 DOI: 10.1093/Hmg/Ddq384  0.322
2010 Zhu R, Heaney J, Nadeau JH, Ali S, Matin A. Deficiency of splicing factor 1 suppresses the occurrence of testicular germ cell tumors. Cancer Research. 70: 7264-72. PMID 20736371 DOI: 10.1158/0008-5472.Can-10-0820  0.37
2010 Poffenberger MC, Shanina I, Aw C, El Wharry N, Straka N, Fang D, Baskin-Hill AE, Spiezio SH, Nadeau JH, Horwitz MS. Novel nonmajor histocompatibility complex-linked loci from mouse chromosome 17 confer susceptibility to viral-mediated chronic autoimmune myocarditis. Circulation. Cardiovascular Genetics. 3: 399-408. PMID 20729557 DOI: 10.1161/Circgenetics.110.936955  0.4
2010 Sa Q, Hart E, Nadeau JH, Hoover-Plow JL. Mouse chromosome 17 candidate modifier genes for thrombosis. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 21: 337-49. PMID 20700597 DOI: 10.1007/S00335-010-9274-6  0.419
2010 Yazbek SN, Spiezio SH, Nadeau JH, Buchner DA. Ancestral paternal genotype controls body weight and food intake for multiple generations. Human Molecular Genetics. 19: 4134-44. PMID 20696673 DOI: 10.1093/Hmg/Ddq332  0.4
2010 Shao H, Sinasac DS, Burrage LC, Hodges CA, Supelak PJ, Palmert MR, Moreno C, Cowley AW, Jacob HJ, Nadeau JH. Analyzing complex traits with congenic strains. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 21: 276-86. PMID 20524000 DOI: 10.1007/S00335-010-9267-5  0.67
2010 Eichler EE, Flint J, Gibson G, Kong A, Leal SM, Moore JH, Nadeau JH. Missing heritability and strategies for finding the underlying causes of complex disease. Nature Reviews. Genetics. 11: 446-50. PMID 20479774 DOI: 10.1038/Nrg2809  0.372
2010 Jepsen KJ, Courtland HW, Nadeau JH. Genetically determined phenotype covariation networks control bone strength. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1581-93. PMID 20200957 DOI: 10.1002/Jbmr.41  0.389
2010 Burrage LC, Baskin-Hill AE, Sinasac DS, Singer JB, Croniger CM, Kirby A, Kulbokas EJ, Daly MJ, Lander ES, Broman KW, Nadeau JH. Genetic resistance to diet-induced obesity in chromosome substitution strains of mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 21: 115-29. PMID 20127486 DOI: 10.1007/S00335-010-9247-9  0.655
2010 Dwyer-Nield LD, McQuillan J, Hill-Baskin A, Radcliffe RA, You M, Nadeau JH, Malkinson AM. Epistatic interactions govern chemically-induced lung tumor susceptibility and Kras mutation site in murine C57BL/6J-ChrA/J chromosome substitution strains. International Journal of Cancer. 126: 125-32. PMID 19609923 DOI: 10.1002/Ijc.24743  0.391
2009 Anderson PD, Nelson VR, Tesar PJ, Nadeau JH. Genetic factors on mouse chromosome 18 affecting susceptibility to testicular germ cell tumors and permissiveness to embryonic stem cell derivation. Cancer Research. 69: 9112-7. PMID 19934337 DOI: 10.1158/0008-5472.Can-09-3342  0.458
2009 Sudbery I, Stalker J, Simpson JT, Keane T, Rust AG, Hurles ME, Walter K, Lynch D, Teboul L, Brown SD, Li H, Ning Z, Nadeau JH, Croniger CM, Durbin R, et al. Deep short-read sequencing of chromosome 17 from the mouse strains A/J and CAST/Ei identifies significant germline variation and candidate genes that regulate liver triglyceride levels. Genome Biology. 10: R112. PMID 19825173 DOI: 10.1186/Gb-2009-10-10-R112  0.42
2009 Nadeau JH. Transgenerational genetic effects on phenotypic variation and disease risk. Human Molecular Genetics. 18: R202-10. PMID 19808797 DOI: 10.1093/Hmg/Ddp366  0.418
2009 Leussis MP, Frayne ML, Saito M, Berry EM, Aldinger KA, Rockwell GN, Hammer RP, Baskin-Hill AE, Singer JB, Nadeau JH, Sklar P, Petryshen TL. Genomic survey of prepulse inhibition in mouse chromosome substitution strains. Genes, Brain, and Behavior. 8: 806-16. PMID 19694817 DOI: 10.1111/J.1601-183X.2009.00526.X  0.406
2009 Hill-Baskin AE, Markiewski MM, Buchner DA, Shao H, DeSantis D, Hsiao G, Subramaniam S, Berger NA, Croniger C, Lambris JD, Nadeau JH. Diet-induced hepatocellular carcinoma in genetically predisposed mice. Human Molecular Genetics. 18: 2975-88. PMID 19454484 DOI: 10.1093/Hmg/Ddp236  0.35
2009 Cook MS, Coveney D, Batchvarov I, Nadeau JH, Capel B. BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1Ter/Ter mice Developmental Biology. 328: 377-383. PMID 19389346 DOI: 10.1016/J.Ydbio.2009.01.041  0.364
2009 Heaney JD, Michelson MV, Youngren KK, Lam MY, Nadeau JH. Deletion of eIF2beta suppresses testicular cancer incidence and causes recessive lethality in agouti-yellow mice. Human Molecular Genetics. 18: 1395-404. PMID 19168544 DOI: 10.1093/Hmg/Ddp045  0.386
2009 Millward CA, Burrage LC, Shao H, Sinasac DS, Kawasoe JH, Hill-Baskin AE, Ernest SR, Gornicka A, Hsieh CW, Pisano S, Nadeau JH, Croniger CM. Genetic factors for resistance to diet-induced obesity and associated metabolic traits on mouse chromosome 17. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 71-82. PMID 19137372 DOI: 10.1007/S00335-008-9165-2  0.773
2009 Jepsen KJ, Hu B, Tommasini SM, Courtland HW, Price C, Cordova M, Nadeau JH. Phenotypic integration of skeletal traits during growth buffers genetic variants affecting the slenderness of femora in inbred mouse strains. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 21-33. PMID 19082857 DOI: 10.1007/S00335-008-9158-1  0.37
2009 Tommasini SM, Hu B, Nadeau JH, Jepsen KJ. Phenotypic integration among trabecular and cortical bone traits establishes mechanical functionality of inbred mouse vertebrae. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 606-20. PMID 19063678 DOI: 10.1359/Jbmr.081224  0.382
2008 Shao H, Burrage LC, Sinasac DS, Hill AE, Ernest SR, O'Brien W, Courtland HW, Jepsen KJ, Kirby A, Kulbokas EJ, Daly MJ, Broman KW, Lander ES, Nadeau JH. Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 19910-4. PMID 19066216 DOI: 10.1073/Pnas.0810388105  0.793
2008 Sa Q, Hart E, Hill AE, Nadeau JH, Hoover-Plow JL. Quantitative trait locus analysis for hemostasis and thrombosis. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 19: 406-12. PMID 18787898 DOI: 10.1007/S00335-008-9122-0  0.408
2008 Kitami T, Rubio R, O'Brien W, Quackenbush J, Nadeau JH. Gene-environment interactions reveal a homeostatic role for cholesterol metabolism during dietary folate perturbation in mice. Physiological Genomics. 35: 182-90. PMID 18697859 DOI: 10.1152/Physiolgenomics.00294.2007  0.782
2008 Buchner DA, Burrage LC, Hill AE, Yazbek SN, O'Brien WE, Croniger CM, Nadeau JH. Resistance to diet-induced obesity in mice with a single substituted chromosome. Physiological Genomics. 35: 116-22. PMID 18628339 DOI: 10.1152/Physiolgenomics.00033.2008  0.685
2008 Heaney JD, Lam MY, Michelson MV, Nadeau JH. Loss of the transmembrane but not the soluble kit ligand isoform increases testicular germ cell tumor susceptibility in mice. Cancer Research. 68: 5193-7. PMID 18593919 DOI: 10.1158/0008-5472.Can-08-0779  0.398
2008 Gürkan E, Olszens KR, Nadeau JH, Loparo KA. Feature identification in circadian rhythms of mice strains using in vivo information. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 19: 366-77. PMID 18592311 DOI: 10.1007/S00335-008-9118-9  0.309
2008 Heaney JD, Nadeau JH. Testicular germ cell tumors in mice: new ways to study a genetically complex trait. Methods in Molecular Biology (Clifton, N.J.). 450: 211-31. PMID 18370062 DOI: 10.1007/978-1-60327-214-8_15  0.464
2008 Prows DR, Hafertepen AP, Winterberg AV, Gibbons WJ, Wesselkamper SC, Singer JB, Hill AE, Nadeau JH, Leikauf GD. Reciprocal congenic lines of mice capture the aliq1 effect on acute lung injury survival time. American Journal of Respiratory Cell and Molecular Biology. 38: 68-77. PMID 17656683 DOI: 10.1165/Rcmb.2006-0162Oc  0.346
2007 Lam MY, Heaney JD, Youngren KK, Kawasoe JH, Nadeau JH. Trans-generational epistasis between Dnd1Ter and other modifier genes controls susceptibility to testicular germ cell tumors. Human Molecular Genetics. 16: 2233-40. PMID 17616517 DOI: 10.1093/Hmg/Ddm175  0.41
2007 Jepsen KJ, Hu B, Tommasini SM, Courtland HW, Price C, Terranova CJ, Nadeau JH. Genetic randomization reveals functional relationships among morphologic and tissue-quality traits that contribute to bone strength and fragility. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 492-507. PMID 17557179 DOI: 10.1007/S00335-007-9017-5  0.343
2006 Hill AE, Lander ES, Nadeau JH. Chromosome substitution strains: a new way to study genetically complex traits. Methods in Molecular Medicine. 128: 153-72. PMID 17071995 DOI: 10.1385/1-59745-159-2:153  0.378
2006 Ernest S, Carter M, Shao H, Hosack A, Lerner N, Colmenares C, Rosenblatt DS, Pao YH, Ross ME, Nadeau JH. Parallel changes in metabolite and expression profiles in crooked-tail mutant and folate-reduced wild-type mice. Human Molecular Genetics. 15: 3387-93. PMID 17050573 DOI: 10.1093/Hmg/Ddl415  0.739
2006 Hoover-Plow J, Shchurin A, Hart E, Sha J, Hill AE, Singer JB, Nadeau JH. Genetic background determines response to hemostasis and thrombosis. Bmc Blood Disorders. 6: 6. PMID 17022820 DOI: 10.1186/1471-2326-6-6  0.446
2006 Nadeau JH, Topol EJ. The genetics of health. Nature Genetics. 38: 1095-8. PMID 17006459 DOI: 10.1038/Ng1006-1095  0.379
2006 Nathan BM, Hodges CA, Supelak PJ, Burrage LC, Nadeau JH, Palmert MR. A quantitative trait locus on chromosome 6 regulates the onset of puberty in mice. Endocrinology. 147: 5132-8. PMID 16873534 DOI: 10.1210/En.2006-0745  0.68
2006 Nadeau JH, Lee C. Genetics: copies count. Nature. 439: 798-9. PMID 16482142 DOI: 10.1038/439798A  0.415
2005 Matin A, Nadeau JH. Search for testicular cancer gene hits dead-end. Cell Cycle (Georgetown, Tex.). 4: 1136-8. PMID 16082220 DOI: 10.4161/Cc.4.9.1992  0.466
2005 Petryshen TL, Kirby A, Hammer RP, Purcell S, O'Leary SB, Singer JB, Hill AE, Nadeau JH, Daly MJ, Sklar P. Two quantitative trait loci for prepulse inhibition of startle identified on mouse chromosome 16 using chromosome substitution strains. Genetics. 171: 1895-904. PMID 15998716 DOI: 10.1534/Genetics.105.045658  0.444
2005 Youngren KK, Coveney D, Peng X, Bhattacharya C, Schmidt LS, Nickerson ML, Lamb BT, Deng JM, Behringer RR, Capel B, Rubin EM, Nadeau JH, Matin A. The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours. Nature. 435: 360-4. PMID 15902260 DOI: 10.1038/Nature03595  0.395
2005 Ernest S, Hosack A, O'Brien WE, Rosenblatt DS, Nadeau JH. Homocysteine levels in A/J and C57BL/6J mice: genetic, diet, gender, and parental effects. Physiological Genomics. 21: 404-10. PMID 15741506 DOI: 10.1152/Physiolgenomics.00199.2004  0.777
2005 Ackerman KG, Huang H, Grasemann H, Puma C, Singer JB, Hill AE, Lander E, Nadeau JH, Churchill GA, Drazen JM, Beier DR. Interacting genetic loci cause airway hyperresponsiveness. Physiological Genomics. 21: 105-11. PMID 15657107 DOI: 10.1152/Physiolgenomics.00267.2004  0.453
2005 Singer JB, Hill AE, Nadeau JH, Lander ES. Mapping quantitative trait loci for anxiety in chromosome substitution strains of mice. Genetics. 169: 855-62. PMID 15371360 DOI: 10.1534/genetics.104.031492  0.302
2004 Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, ... ... Nadeau JH, et al. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature Genetics. 36: 1133-7. PMID 15514660 DOI: 10.1038/Ng1104-1133  0.383
2004 Kitami T, Ernest S, Gallaugher L, Friedman L, Frankel WN, Nadeau JH. Genetic and phenotypic analysis of seizure susceptibility in PL/J mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 698-703. PMID 15389317 DOI: 10.1007/S00335-004-3007-7  0.732
2004 Krewson TD, Supelak PJ, Hill AE, Singer JB, Lander ES, Nadeau JH, Palmert MR. Chromosomes 6 and 13 harbor genes that regulate pubertal timing in mouse chromosome substitution strains. Endocrinology. 145: 4447-51. PMID 15284200 DOI: 10.1210/En.2004-0543  0.426
2004 Singer JB, Hill AE, Burrage LC, Olszens KR, Song J, Justice M, O'Brien WE, Conti DV, Witte JS, Lander ES, Nadeau JH. Genetic dissection of complex traits with chromosome substitution strains of mice. Science (New York, N.Y.). 304: 445-8. PMID 15031436 DOI: 10.1126/Science.1093139  0.699
2004 Lam MY, Youngren KK, Nadeau JH. Enhancers and suppressors of testicular cancer susceptibility in single- and double-mutant mice. Genetics. 166: 925-33. PMID 15020477 DOI: 10.1534/Genetics.166.2.925  0.435
2003 Ernest S, Carter M, Hosack A, Rosenblatt D, Ross E, Nadeau JH. Nutrigenes, functional genomics and systems biology. The Journal of Nutrition. 133: 4267-8. PMID 14652385 DOI: 10.1093/Jn/133.12.4267  0.752
2003 Nishimura I, Drake TA, Lusis AJ, Lyons KM, Nadeau JH, Zernik J. ENU large-scale mutagenesis and quantitative trait linkage (QTL) analysis in mice: novel technologies for searching polygenetic determinants of craniofacial abnormalities. Critical Reviews in Oral Biology and Medicine : An Official Publication of the American Association of Oral Biologists. 14: 320-30. PMID 14530301 DOI: 10.1177/154411130301400503  0.43
2003 Nadeau JH, Burrage LC, Restivo J, Pao YH, Churchill G, Hoit BD. Pleiotropy, homeostasis, and functional networks based on assays of cardiovascular traits in genetically randomized populations. Genome Research. 13: 2082-91. PMID 12952877 DOI: 10.1101/Gr.1186603  0.667
2003 Nadeau JH. Genetics. Modifying the message. Science (New York, N.Y.). 301: 927-8. PMID 12920288 DOI: 10.1126/Science.1088948  0.413
2003 Nadeau JH. Modifier genes and protective alleles in humans and mice. Current Opinion in Genetics & Development. 13: 290-5. PMID 12787792 DOI: 10.1016/S0959-437X(03)00061-3  0.417
2003 Lam MY, Nadeau JH. Genetic control of susceptibility to spontaneous testicular germ cell tumors in mice. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 111: 184-90; discussion 1. PMID 12752260  0.37
2003 Jepsen KJ, Akkus OJ, Majeska RJ, Nadeau JH. Hierarchical relationship between bone traits and mechanical properties in inbred mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 97-104. PMID 12584605 DOI: 10.1007/S00335-002-3045-Y  0.323
2003 Youngren KK, Nadeau JH, Matin A. Testicular cancer susceptibility in the 129.MOLF-Chr19 mouse strain: additive effects, gene interactions and epigenetic modifications. Human Molecular Genetics. 12: 389-98. PMID 12566386 DOI: 10.1093/Hmg/Ddg036  0.443
2002 Glazier AM, Nadeau JH, Aitman TJ. Finding genes that underlie complex traits. Science (New York, N.Y.). 298: 2345-9. PMID 12493905 DOI: 10.1126/science.1076641  0.302
2002 Nadeau JH. Single nucleotide polymorphisms: tackling complexity. Nature. 420: 517-8. PMID 12466848 DOI: 10.1038/420517A  0.369
2002 Erhart MA, Lekgothoane S, Grenier J, Nadeau JH. Pattern of segmental recombination in the distal inversion of mouse t haplotypes. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 13: 438-44. PMID 12226709 DOI: 10.1007/S00335-002-3012-7  0.315
2002 Kitami T, Nadeau JH. Biochemical networking contributes more to genetic buffering in human and mouse metabolic pathways than does gene duplication. Nature Genetics. 32: 191-4. PMID 12161750 DOI: 10.1038/Ng945  0.767
2002 Ernest S, Christensen B, Gilfix BM, Mamer OA, Hosack A, Rodier M, Colmenares C, McGrath J, Bale A, Balling R, Sankoff D, Rosenblatt DS, Nadeau JH. Genetic and molecular control of folate-homocysteine metabolism in mutant mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 13: 259-67. PMID 12016514 DOI: 10.1007/S00335-001-3054-2  0.778
2002 Percec I, Plenge RM, Nadeau JH, Bartolomei MS, Willard HF. Autosomal dominant mutations affecting X inactivation choice in the mouse Science. 296: 1136-1139. PMID 12004136 DOI: 10.1126/Science.1070087  0.332
2002 Han F, Subramanian S, Price ER, Nadeau J, Strohl KP. Periodic breathing in the mouse. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 1133-40. PMID 11842050 DOI: 10.1152/Japplphysiol.00785.2001  0.34
2002 Matin A, Nadeau JH. Sensitized polygenic trait analysis. Trends in Genetics : Tig. 17: 727-31. PMID 11718927 DOI: 10.1016/S0168-9525(01)02528-8  0.396
2001 Jepsen KJ, Pennington DE, Lee YL, Warman M, Nadeau J. Bone brittleness varies with genetic background in A/J and C57BL/6J inbred mice Journal of Bone and Mineral Research. 16: 1854-1862. PMID 11585350 DOI: 10.1359/Jbmr.2001.16.10.1854  0.339
2001 Hoit BD, Nadeau JH. Phenotype-driven genetic approaches in mice: high-throughput phenotyping for discovering new models of cardiovascular disease. Trends in Cardiovascular Medicine. 11: 82-9. PMID 11530297 DOI: 10.1016/S1050-1738(01)00090-1  0.429
2001 Robin NH, Nadeau JH. Disorganization in mice and humans. American Journal of Medical Genetics. 101: 334-8. PMID 11471156 DOI: 10.1002/1096-8628(20010715)101:4<334::Aid-Ajmg1233>3.0.Co;2-7  0.395
2001 Nadeau JH. Modifier genes in mice and humans. Nature Reviews. Genetics. 2: 165-74. PMID 11256068 DOI: 10.1038/35056009  0.453
2001 Jiang LI, Nadeau JH. 129/Sv mice--a model system for studying germ cell biology and testicular cancer. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 12: 89-94. PMID 11210194 DOI: 10.1007/S003350010257  0.465
2001 Chadwick LH, McCandless SE, Silverman GL, Schwartz S, Westaway D, Nadeau JH. Betaine-homocysteine methyltransferase-2: cDNA cloning, gene sequence, physical mapping, and expression of the human and mouse genes. Genomics. 70: 66-73. PMID 11087663 DOI: 10.1006/Geno.2000.6319  0.363
2000 Nadeau JH, Frankel WN. The roads from phenotypic variation to gene discovery: Mutagenesis versus QTLs Nature Genetics. 25: 381-384. PMID 10932178 DOI: 10.1038/78051  0.424
2000 Nadeau JH. Muta-genetics or muta-genomics: the feasibility of large-scale mutagenesis and phenotyping programs. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 11: 603-7. PMID 10886031 DOI: 10.1007/S003350010115  0.316
2000 Nadeau JH, Singer JB, Matin A, Lander ES. Analysing complex genetic traits with chromosome substitution strains. Nature Genetics. 24: 221-5. PMID 10700173 DOI: 10.1038/73427  0.435
2000 Keri RA, Lozada KL, Abdul-Karim FW, Nadeau JH, Nilson JH. Luteinizing hormone induction of ovarian tumors: oligogenic differences between mouse strains dictates tumor disposition. Proceedings of the National Academy of Sciences of the United States of America. 97: 383-7. PMID 10618427 DOI: 10.1073/Pnas.97.1.383  0.336
2000 Faiella A, Wernig M, Consalez GG, Hostick U, Hofmann C, Hustert E, Boncinelli E, Balling R, Nadeau JH. A mouse model for valproate teratogenicity: parental effects, homeotic transformations, and altered HOX expression. Human Molecular Genetics. 9: 227-36. PMID 10607833 DOI: 10.1093/Hmg/9.2.227  0.379
1999 Matin A, Collin GB, Asada Y, Varnum D, Nadeau JH. Susceptibility to testicular germ-cell tumours in a 129.MOLF-Chr 19 chromosome substitution strain. Nature Genetics. 23: 237-40. PMID 10508525 DOI: 10.1038/13874  0.432
1999 Colvin JS, Feldman B, Nadeau JH, Goldfarb M, Ornitz DM. Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 216: 72-88. PMID 10474167 DOI: 10.1002/(Sici)1097-0177(199909)216:1<72::Aid-Dvdy9>3.0.Co;2-9  0.317
1998 Nadeau JH, Dunn PJ. Genomic strategies for defining and dissecting developmental and physiological pathways. Current Opinion in Genetics & Development. 8: 311-5. PMID 9690993 DOI: 10.1016/S0959-437X(98)80087-7  0.396
1998 Matin A, Collin GB, Asada Y, Varnum D, Martone DL, Nadeau JH. Simple sequence length polymorphisms (SSLPs) that distinguish MOLF/Ei and 129/Sv inbred strains of laboratory mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 668-70. PMID 9680390 DOI: 10.1007/S003359900842  0.347
1998 Matin A, Collin GB, Varnum DS, Nadeau JH. Testicular teratocarcinogenesis in mice--a review. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 106: 174-82. PMID 9524576 DOI: 10.1111/J.1699-0463.1998.Tb01333.X  0.431
1998 Robin NH, Abbadi N, McCandless SE, Nadeau JH. Disorganization in mice and humans and its relation to sporadic birth defects. American Journal of Medical Genetics. 73: 425-36. PMID 9415470 DOI: 10.1002/(Sici)1096-8628(19971231)73:4<425::Aid-Ajmg11>3.0.Co;2-T  0.352
1997 Threadgill DW, Matin A, Yee D, Carrasquillo MM, Henry KR, Rollins KG, Nadeau JH, Magnuson T. SSLPs to map genetic differences between the 129 inbred strains and closed-colony, random-bred CD-I mice Mammalian Genome. 8: 441-442. PMID 9166591 DOI: 10.1007/S003359900464  0.4
1997 Threadgill DW, Yee D, Matin A, Nadeau JH, Magnuson T. Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain Mammalian Genome. 8: 390-393. PMID 9166580 DOI: 10.1007/S003359900453  0.41
1997 DiDonato CJ, Chen XN, Noya D, Korenberg JR, Nadeau JH, Simard LR. Cloning, characterization, and copy number of the murine survival motor neuron gene: homolog of the spinal muscular atrophy-determining gene. Genome Research. 7: 339-52. PMID 9110173 DOI: 10.1101/Gr.7.4.339  0.356
1997 DiDonato CJ, Nadeau JH, Simard LR. The mouse neuronal apoptosis inhibitory protein gene maps to a conserved syntenic region of mouse Chromosome 13 Mammalian Genome. 8: 222. PMID 9069126 DOI: 10.1007/S003359900394  0.323
1996 Rozmahel R, Wilschanski M, Matin A, Plyte S, Oliver M, Auerbach W, Moore A, Forstner J, Durie P, Nadeau J, Bear C, Tsui LC. Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor Nature Genetics. 12: 280-287. PMID 8589719 DOI: 10.1038/Ng0396-280  0.302
1995 Helwig U, Imai K, Schmahl W, Thomas BE, Varnum DS, Nadeau JH, Balling R. Interaction between undulated and Patch leads to an extreme form of spina bifida in double-mutant mice. Nature Genetics. 11: 60-3. PMID 7550316 DOI: 10.1038/ng0995-60  0.305
1994 Asada Y, Varnum DS, Frankel WN, Nadeau JH. A mutation in the Ter gene causing increased susceptibility to testicular teratomas maps to mouse chromosome 18 Nature Genetics. 6: 363-368. PMID 8054975 DOI: 10.1038/ng0494-363  0.324
1992 Nadeau JH, Compton JG, Giguère V, Rossant J, Varmuza S. Close linkage of retinoic acid receptor genes with homeobox- and keratin-encoding genes on paralogous segments of mouse chromosomes 11 and 15. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 3: 202-8. PMID 1377062 DOI: 10.1007/Bf00355720  0.364
1991 Nadeau JH, Herrmann B, Bucan M, Burkart D, Crosby JL, Erhart MA, Kosowsky M, Kraus JP, Michiels F, Schnattinger A, Tchetgen MB, Varnum D, Willison K, Lehrach H, Barlow D. Genetic maps of mouse Chromosome 17 including 12 new anonymous DNA loci and 25 anchor loci Genomics. 9: 78-89. PMID 1672293 DOI: 10.1016/0888-7543(91)90223-2  0.302
1990 Lussier M, Filion M, Compton JG, Nadeau JH, Lapointe L, Royal A. The mouse keratin 19-encoding gene: sequence, structure and chromosomal assignment. Gene. 95: 203-13. PMID 1701153 DOI: 10.1016/0378-1119(90)90363-V  0.319
1989 Nadeau JH. Maps of linkage and synteny homologies between mouse and man. Trends in Genetics : Tig. 5: 82-6. PMID 2660365 DOI: 10.1016/0168-9525(89)90031-0  0.348
1989 Stone JC, Crosby JL, Kozak CA, Schievella AR, Bernards R, Nadeau JH. The murine retinoblastoma homolog maps to chromosome 14 near Es-10 Genomics. 5: 70-75. PMID 2570031 DOI: 10.1016/0888-7543(89)90088-8  0.318
1989 Nadeau JH, Berger FG, Cox DR, Crosby JL, Davisson MT, Ferrara D, Fuchs E, Hari C, Hunihan L, Lalley PA, Langley SH, Martin GR, Nichols L, Phillips SJ, Roderick TH, et al. A family of type I keratin genes and the homeobox-2 gene complex are closely linked to the rex locus on mouse chromosome 11 Genomics. 5: 454-462. PMID 2482246 DOI: 10.1016/0888-7543(89)90009-8  0.366
1986 Sidman CL, Marshall JD, Beamer WG, Nadeau JH, Unanue ER. Two loci affecting B cell responses to B cell maturation factors. The Journal of Experimental Medicine. 163: 116-28. PMID 3079812 DOI: 10.1084/Jem.163.1.116  0.355
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