Nancy R. Manley - Publications

Medical College of Georgia, Augusta, GA, United States 
Molecular Biology

80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Li J, Gordon J, Chen ELY, Xiao S, Wu L, Zúñiga-Pflücker JC, Manley NR. NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development. Development (Cambridge, England). PMID 32467240 DOI: 10.1242/Dev.178988  0.442
2020 Martini R, Newman L, Manley N, Davis M. Abstract P1-03-08: In vivo investigation of the Duffy antigen receptor for chemokines (DARC/ACKR1) and tumor-infiltrating immune cells in the breast tumor microenvironment Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P1-03-08  0.311
2020 Martini R, Jenkins B, Deeb D, Ravichandran H, Ginter P, Cheng E, Hoda S, Chitale D, Ali H, Walker E, Bensenhaver J, Elemento O, Manley N, Newman L, Davis M. Abstract 4975: Breast tumor expression of DARC/ACKR1 and impacts on disease progression and immune cell recruitment in the tumor microenvironment Cancer Research. 80: 4975-4975. DOI: 10.1158/1538-7445.Am2020-4975  0.369
2019 Martini RN, Jenkins BD, Newman LA, Manley N, Davis MB. Abstract 4630:In vivocharacterization of the Duffy antigen receptor for chemokines (DARC/ACKR1) in breast cancer tumor progression Cancer Research. 79: 4630-4630. DOI: 10.1158/1538-7445.Am2019-4630  0.36
2018 Peissig K, Condie BG, Manley NR. Embryology of the Parathyroid Glands. Endocrinology and Metabolism Clinics of North America. 47: 733-742. PMID 30390809 DOI: 10.1016/J.Ecl.2018.07.002  0.315
2018 Singarapu N, Ma K, Reeh KAG, Shen J, Lancaster JN, Yi S, Xie H, Orkin SH, Manley NR, Ehrlich LIR, Jiang N, Richie ER. Polycomb Repressive Complex 2 is essential for development and maintenance of a functional TEC compartment. Scientific Reports. 8: 14335. PMID 30254371 DOI: 10.1038/S41598-018-32729-Z  0.447
2018 Xiao S, Zhang W, Manley NR. Thymic B cell development is controlled by the B potential of progenitors via both hematopoietic-intrinsic and thymic microenvironment-intrinsic regulatory mechanisms. Plos One. 13: e0193189. PMID 29462202 DOI: 10.1371/Journal.Pone.0193189  0.351
2018 Xiao S, Zhang W, Manley NR. Thymic epithelial cell-derived signals control B progenitor formation and proliferation in the thymus by regulating Let-7 and Arid3a. Plos One. 13: e0193188. PMID 29462197 DOI: 10.1371/Journal.Pone.0193188  0.429
2018 Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P, Kinsella S, Palikuqi B, Ginsberg M, Young LF, Kreines F, ... ... Manley NR, et al. Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration. Science Immunology. 3. PMID 29330161 DOI: 10.1126/Sciimmunol.Aal2736  0.367
2017 Xiao S, Shterev ID, Zhang W, Young L, Shieh JH, Moore M, van den Brink M, Sempowski GD, Manley NR. Sublethal Total Body Irradiation Causes Long-Term Deficits in Thymus Function by Reducing Lymphoid Progenitors. Journal of Immunology (Baltimore, Md. : 1950). PMID 28931604 DOI: 10.4049/Jimmunol.1600934  0.3
2017 Sornborger A, Li J, Timmons C, Lupu F, Eggenschwiler J, Takahama Y, Manley NR. MiCASA is a new method for quantifying cellular organization. Nature Communications. 8: 15619. PMID 28555660 DOI: 10.1038/Ncomms15619  0.338
2016 Bain VE, Gordon J, O'Neil JD, Ramos I, Richie ER, Manley NR. Tissue-specific roles for Sonic hedgehog signaling in establishing thymus and parathyroid organ fate. Development (Cambridge, England). PMID 27633995 DOI: 10.1242/Dev.141903  0.394
2016 Chojnowski JL, Trau HA, Masuda K, Manley NR. Temporal and spatial requirements for Hoxa3 in mouse embryonic development. Developmental Biology. PMID 27178667 DOI: 10.1016/J.Ydbio.2016.05.010  0.481
2015 Chen D, Wang X, Liang D, Gordon J, Mittal A, Manley N, Degenhardt K, Astrof S. Fibronectin signals through integrin α5β1 to regulate cardiovascular development in a cell type-specific manner. Developmental Biology. PMID 26434918 DOI: 10.1016/J.Ydbio.2015.09.016  0.42
2015 Bredenkamp N, Jin X, Liu D, O'Neill KE, Manley NR, Blackburn CC. Construction of a functional thymic microenvironment from pluripotent stem cells for the induction of central tolerance. Regenerative Medicine. 10: 317-29. PMID 25933240 DOI: 10.2217/Rme.15.8  0.363
2014 Chojnowski JL, Masuda K, Trau HA, Thomas K, Capecchi M, Manley NR. Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse. Development (Cambridge, England). 141: 3697-708. PMID 25249461 DOI: 10.1242/Dev.110833  0.498
2014 Bredenkamp N, Ulyanchenko S, O'Neill KE, Manley NR, Vaidya HJ, Blackburn CC. An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts. Nature Cell Biology. 16: 902-8. PMID 25150981 DOI: 10.1038/Ncb3023  0.406
2014 Reeh KA, Cardenas KT, Bain VE, Liu Z, Laurent M, Manley NR, Richie ER. Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis. Development (Cambridge, England). 141: 2950-8. PMID 25053428 DOI: 10.1242/Dev.111641  0.468
2014 Gordon J, Moore BA, Blackburn CC, Manley NR. Serum-free culture of mid-gestation mouse embryos: a tool for the study of endoderm-derived organs. Methods in Molecular Biology (Clifton, N.J.). 1092: 183-94. PMID 24318821 DOI: 10.1007/978-1-60327-292-6_12  0.442
2013 Li J, Liu Z, Xiao S, Manley NR. Transdifferentiation of parathyroid cells into cervical thymi promotes atypical T-cell development. Nature Communications. 4: 2959. PMID 24343363 DOI: 10.1038/Ncomms3959  0.423
2013 Bryson JL, Griffith AV, Hughes B, Saito F, Takahama Y, Richie ER, Manley NR. Cell-autonomous defects in thymic epithelial cells disrupt endothelial-perivascular cell interactions in the mouse thymus. Plos One. 8: e65196. PMID 23750244 DOI: 10.1371/Journal.Pone.0065196  0.406
2013 Garfin PM, Min D, Bryson JL, Serwold T, Edris B, Blackburn CC, Richie ER, Weinberg KI, Manley NR, Sage J, Viatour P. Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. The Journal of Experimental Medicine. 210: 1087-97. PMID 23669396 DOI: 10.1084/Jem.20121716  0.375
2012 Gardiner JR, Jackson AL, Gordon J, Lickert H, Manley NR, Basson MA. Localised inhibition of FGF signalling in the third pharyngeal pouch is required for normal thymus and parathyroid organogenesis. Development (Cambridge, England). 139: 3456-66. PMID 22912418 DOI: 10.1242/Dev.079400  0.455
2012 Chinn IK, Blackburn CC, Manley NR, Sempowski GD. Changes in primary lymphoid organs with aging. Seminars in Immunology. 24: 309-20. PMID 22559987 DOI: 10.1016/J.Smim.2012.04.005  0.304
2012 Garfin PM, Viatour P, Min D, Bryson J, Weinberg KI, Manley NR, Sage J. RB Controls Size, Cellularity, and T Cell Output of the Mouse Thymus Blood. 120: 835-835. DOI: 10.1182/Blood.V120.21.835.835  0.387
2011 Wei Q, Manley NR, Condie BG. Whole mount in situ hybridization of E8.5 to E11.5 mouse embryos. Journal of Visualized Experiments : Jove. PMID 22005971 DOI: 10.3791/2797  0.344
2011 Bryson JL, Coles MC, Manley NR. A method for labeling vasculature in embryonic mice. Journal of Visualized Experiments : Jove. PMID 22005349 DOI: 10.3791/3267  0.361
2011 Gordon J, Manley NR. Mechanisms of thymus organogenesis and morphogenesis. Development (Cambridge, England). 138: 3865-78. PMID 21862553 DOI: 10.1242/Dev.059998  0.39
2011 Manley NR, Richie ER, Blackburn CC, Condie BG, Sage J. Structure and function of the thymic microenvironment. Frontiers in Bioscience (Landmark Edition). 16: 2461-77. PMID 21622189 DOI: 10.2741/3866  0.369
2011 Gordon J, Manley N. Activation of canonical Wnt signaling in the thymus alters epithelial cell identity Developmental Biology. 356: 161-162. DOI: 10.1016/J.Ydbio.2011.05.598  0.341
2010 Liu Z, Farley A, Chen L, Kirby BJ, Kovacs CS, Blackburn CC, Manley NR. Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions. Plos Genetics. 6: e1001251. PMID 21203493 DOI: 10.1371/Journal.Pgen.1001251  0.42
2010 Xiao S, Manley NR. Impaired thymic selection and abnormal antigen-specific T cell responses in Foxn1(Δ/Δ) mutant mice. Plos One. 5: e15396. PMID 21079757 DOI: 10.1371/Journal.Pone.0015396  0.425
2010 Manley NR, Condie BG. Transcriptional regulation of thymus organogenesis and thymic epithelial cell differentiation. Progress in Molecular Biology and Translational Science. 92: 103-20. PMID 20800818 DOI: 10.1016/S1877-1173(10)92005-X  0.406
2010 Foster KE, Gordon J, Cardenas K, Veiga-Fernandes H, Makinen T, Grigorieva E, Wilkinson DG, Blackburn CC, Richie E, Manley NR, Adams RH, Kioussis D, Coles MC. EphB-ephrin-B2 interactions are required for thymus migration during organogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 13414-9. PMID 20616004 DOI: 10.1073/Pnas.1003747107  0.389
2010 Chen L, Zhao P, Wells L, Amemiya CT, Condie BG, Manley NR. Mouse and zebrafish Hoxa3 orthologues have nonequivalent in vivo protein function. Proceedings of the National Academy of Sciences of the United States of America. 107: 10555-60. PMID 20498049 DOI: 10.1073/Pnas.1005129107  0.371
2010 Grigorieva IV, Mirczuk S, Gaynor KU, Nesbit MA, Grigorieva EF, Wei Q, Ali A, Fairclough RJ, Stacey JM, Stechman MJ, Mihai R, Kurek D, Fraser WD, Hough T, Condie BG, ... Manley N, et al. Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2. The Journal of Clinical Investigation. 120: 2144-55. PMID 20484821 DOI: 10.1172/Jci42021  0.425
2010 Nam KT, Lee HJ, Smith JJ, Lapierre LA, Kamath VP, Chen X, Aronow BJ, Yeatman TJ, Bhartur SG, Calhoun BC, Condie B, Manley NR, Beauchamp RD, Coffey RJ, Goldenring JR. Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas. The Journal of Clinical Investigation. 120: 840-9. PMID 20197623 DOI: 10.1172/Jci40728  0.371
2010 Gordon J, Patel SR, Mishina Y, Manley NR. Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis. Developmental Biology. 339: 141-54. PMID 20043899 DOI: 10.1016/J.Ydbio.2009.12.026  0.492
2009 Fraser GJ, Hulsey CD, Bloomquist RF, Uyesugi K, Manley NR, Streelman JT. An ancient gene network is co-opted for teeth on old and new jaws. Plos Biology. 7: e31. PMID 19215146 DOI: 10.1371/Journal.Pbio.1000031  0.333
2009 Griffith AV, Cardenas K, Carter C, Gordon J, Iberg A, Engleka K, Epstein JA, Manley NR, Richie ER. Increased thymus- and decreased parathyroid-fated organ domains in Splotch mutant embryos. Developmental Biology. 327: 216-27. PMID 19135046 DOI: 10.1016/J.Ydbio.2008.12.019  0.402
2009 Chen L, Xiao S, Manley NR. Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner. Blood. 113: 567-74. PMID 18978204 DOI: 10.1182/Blood-2008-05-156265  0.473
2009 Manley NR. Foxn1 and the Rise and Fall of the Thymic Microenvironment. Blood. 114: SCI-50-SCI-50. DOI: 10.1182/Blood.V114.22.Sci-50.Sci-50  0.435
2008 Koch U, Fiorini E, Benedito R, Besseyrias V, Schuster-Gossler K, Pierres M, Manley NR, Duarte A, Macdonald HR, Radtke F. Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. The Journal of Experimental Medicine. 205: 2515-23. PMID 18824585 DOI: 10.1084/Jem.20080829  0.43
2008 Li Y, Gordon J, Manley NR, Litingtung Y, Chiang C. Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis. Developmental Biology. 322: 145-55. PMID 18692041 DOI: 10.1016/J.Ydbio.2008.07.021  0.381
2008 Xiao S, Su DM, Manley NR. T cell development from kit-negative progenitors in the Foxn1Delta/Delta mutant thymus. Journal of Immunology (Baltimore, Md. : 1950). 180: 914-21. PMID 18178831 DOI: 10.4049/Jimmunol.180.2.914  0.438
2007 Xiao S, Su DM, Manley NR. Atypical memory phenotype T cells with low homeostatic potential and impaired TCR signaling and regulatory T cell function in Foxn1Delta/Delta mutant mice. Journal of Immunology (Baltimore, Md. : 1950). 179: 8153-63. PMID 18056358 DOI: 10.4049/Jimmunol.179.12.8153  0.43
2007 Gordon J, Xiao S, Hughes B, Su DM, Navarre SP, Condie BG, Manley NR. Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus. Bmc Developmental Biology. 7: 69. PMID 17577402 DOI: 10.1186/1471-213X-7-69  0.437
2007 Liu Z, Yu S, Manley NR. Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia. Developmental Biology. 305: 333-46. PMID 17382312 DOI: 10.1016/J.Ydbio.2007.02.014  0.456
2007 Liston A, Farr AG, Chen Z, Benoist C, Mathis D, Manley NR, Rudensky AY. Lack of Foxp3 function and expression in the thymic epithelium. The Journal of Experimental Medicine. 204: 475-80. PMID 17353370 DOI: 10.1084/Jem.20062465  0.408
2007 Bryson JL, Hughes BM, Venables A, Richie E, Manley NR. Foxn1 dependent immigration of endothelial progenitor cells into mouse embryo thymus Developmental Biology. 306: 421. DOI: 10.1016/J.Ydbio.2007.03.656  0.411
2007 Yu SF, Liu Z, Manley NR. Molecular regulation of parathyroid organogenesis in the mouse Developmental Biology. 306: 421. DOI: 10.1016/J.Ydbio.2007.03.655  0.311
2007 Gordon J, Manley N, Williams T, Bain VE. WITHDRAWN: AP2-a is required for normal thymus development Developmental Biology. DOI: 10.1016/J.Ydbio.2007.03.311  0.302
2007 Venables A, Hughes BM, Richie E, Bryson JL, Manley NR. WITHDRAWN: Foxn1 dependent immigration of endothelial progenitor cells into mouse embryo thymus Developmental Biology. DOI: 10.1016/J.Ydbio.2007.03.310  0.411
2007 Manley NR, Yu SF, Liu Z. WITHDRAWN: Molecular regulation of parathyroid organogenesis in the mouse Developmental Biology. DOI: 10.1016/J.Ydbio.2007.03.309  0.312
2006 Liu C, Saito F, Liu Z, Lei Y, Uehara S, Love P, Lipp M, Kondo S, Manley N, Takahama Y. Coordination between CCR7- and CCR9-mediated chemokine signals in prevascular fetal thymus colonization. Blood. 108: 2531-9. PMID 16809609 DOI: 10.1182/Blood-2006-05-024190  0.387
2006 Patel SR, Gordon J, Mahbub F, Blackburn CC, Manley NR. Bmp4 and Noggin expression during early thymus and parathyroid organogenesis. Gene Expression Patterns : Gep. 6: 794-9. PMID 16517216 DOI: 10.1016/J.Modgep.2006.01.011  0.456
2006 Li Y, Gordon J, Litingtung Y, Manley NR, Chiang C. Bmp4 is required for the initiation of tracheal development Developmental Biology. 295: 459-460. DOI: 10.1016/J.Ydbio.2006.04.415  0.341
2006 Gordon J, Manley NR. Tissue-specific requirements for BMP signaling during thymus and parathyroid morphogenesis Developmental Biology. 295: 455. DOI: 10.1016/J.Ydbio.2006.04.402  0.316
2005 Moore-Scott BA, Manley NR. Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs. Developmental Biology. 278: 323-35. PMID 15680353 DOI: 10.1016/J.Ydbio.2004.10.027  0.725
2005 Zamisch M, Moore-Scott B, Su DM, Lucas PJ, Manley N, Richie ER. Ontogeny and regulation of IL-7-expressing thymic epithelial cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 60-7. PMID 15611228 DOI: 10.4049/Jimmunol.174.1.60  0.703
2005 Gordon J, Wilson VA, Moore-Scott BA, Manley NR, Blackburn CC. In vivo and in vitro assays of thymic organogenesis. Methods in Molecular Medicine. 105: 303-10. PMID 15492403 DOI: 10.1385/1-59259-826-9:303  0.723
2004 Manley NR, Selleri L, Brendolan A, Gordon J, Cleary ML. Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs. Developmental Biology. 276: 301-12. PMID 15581866 DOI: 10.1016/J.Ydbio.2004.08.030  0.415
2004 Gordon J, Wilson VA, Blair NF, Sheridan J, Farley A, Wilson L, Manley NR, Blackburn CC. Functional evidence for a single endodermal origin for the thymic epithelium. Nature Immunology. 5: 546-53. PMID 15098031 DOI: 10.1038/Ni1064  0.399
2004 Blackburn CC, Manley NR. Developing a new paradigm for thymus organogenesis. Nature Reviews. Immunology. 4: 278-89. PMID 15057786 DOI: 10.1038/Nri1331  0.39
2004 Manley NR, Blackburn CC. Thymus and Parathyroid Organogenesis Handbook of Stem Cells. 1: 391-406. DOI: 10.1016/B978-012436643-5/50046-8  0.301
2003 Su DM, Navarre S, Oh WJ, Condie BG, Manley NR. A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation. Nature Immunology. 4: 1128-35. PMID 14528302 DOI: 10.1038/Ni983  0.409
2003 Moore-Scott BA, Gordon J, Blackburn CC, Condie BG, Manley NR. New serum-free in vitro culture technique for midgestation mouse embryos. Genesis (New York, N.Y. : 2000). 35: 164-8. PMID 12640621 DOI: 10.1002/Gene.10179  0.702
2003 Manley NR, Blackburn CC. A developmental look at thymus organogenesis: where do the non-hematopoietic cells in the thymus come from? Current Opinion in Immunology. 15: 225-32. PMID 12633674 DOI: 10.1016/S0952-7915(03)00006-2  0.41
2002 Su DM, Manley NR. Stage-specific changes in fetal thymocyte proliferation during the CD4-8- to CD4+8+ transition in wild type, Rag1-/-, and Hoxa3,Pax1 mutant mice. Bmc Immunology. 3: 12. PMID 12241558 DOI: 10.1186/1471-2172-3-12  0.377
2002 Blackburn CC, Manley NR, Palmer DB, Boyd RL, Anderson G, Ritter MA. One for all and all for one: thymic epithelial stem cells and regeneration. Trends in Immunology. 23: 391-5. PMID 12133801 DOI: 10.1016/S1471-4906(02)02265-2  0.373
2001 Manley NR, Barrow JR, Zhang T, Capecchi MR. Hoxb2 and hoxb4 act together to specify ventral body wall formation. Developmental Biology. 237: 130-44. PMID 11518511 DOI: 10.1006/Dbio.2001.0365  0.34
2001 Su D, Ellis S, Napier A, Lee K, Manley NR. Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis. Developmental Biology. 236: 316-29. PMID 11476574 DOI: 10.1006/Dbio.2001.0342  0.446
2001 Hadland BK, Manley NR, Su D, Longmore GD, Moore CL, Wolfe MS, Schroeter EH, Kopan R. Gamma -secretase inhibitors repress thymocyte development. Proceedings of the National Academy of Sciences of the United States of America. 98: 7487-91. PMID 11416218 DOI: 10.1073/Pnas.131202798  0.314
2001 Gordon J, Bennett AR, Blackburn CC, Manley NR. Gcm2 and Foxn1 mark early parathyroid- and thymus-specific domains in the developing third pharyngeal pouch. Mechanisms of Development. 103: 141-3. PMID 11335122 DOI: 10.1016/S0925-4773(01)00333-1  0.419
2000 Manley NR. Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation. Seminars in Immunology. 12: 421-8. PMID 11085174 DOI: 10.1006/Smim.2000.0263  0.452
2000 Mulder GB, Manley N, Grant J, Schmidt K, Zeng W, Eckhoff C, Maggio-Price L. Effects of excess vitamin A on development of cranial neural crest-derived structures: a neonatal and embryologic study. Teratology. 62: 214-26. PMID 10992263 DOI: 10.1002/1096-9926(200010)62:4<214::Aid-Tera7>3.0.Co;2-N  0.347
2000 Su DM, Manley NR. Hoxa3 and pax1 transcription factors regulate the ability of fetal thymic epithelial cells to promote thymocyte development. Journal of Immunology (Baltimore, Md. : 1950). 164: 5753-60. PMID 10820253 DOI: 10.4049/Jimmunol.164.11.5753  0.405
1998 Mulder GB, Manley N, Maggio-Price L. Retinoic acid-induced thymic abnormalities in the mouse are associated with altered pharyngeal morphology, thymocyte maturation defects, and altered expression of Hoxa3 and Pax1. Teratology. 58: 263-75. PMID 9894676 DOI: 10.1002/(Sici)1096-9926(199812)58:6<263::Aid-Tera8>3.0.Co;2-A  0.383
1998 Manley NR, Capecchi MR. Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands. Developmental Biology. 195: 1-15. PMID 9520319 DOI: 10.1006/Dbio.1997.8827  0.378
1997 Manley NR, Capecchi MR. Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures. Developmental Biology. 192: 274-88. PMID 9441667 DOI: 10.1006/Dbio.1997.8765  0.342
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