Tomas A. Prolla - Publications

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
Genetics, Animal Physiology Biology, Molecular Biology

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Serna E, Mastaloudis A, Martorell P, Wood SM, Hester SN, Bartlett M, Prolla TA, Viña J. A Novel Micronutrient Blend Mimics Calorie Restriction Transcriptomics in Multiple Tissues of Mice and Increases Lifespan and Mobility in . Nutrients. 12. PMID 32075050 DOI: 10.3390/nu12020486  0.48
2017 Barger JL, Vann JM, Cray NL, Pugh TD, Mastaloudis A, Hester SN, Wood SM, Newton MA, Weindruch R, Prolla TA. Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics. Aging Cell. PMID 28556428 DOI: 10.1111/acel.12608  1
2017 Someya S, Kujoth GC, Kim MJ, Hacker TA, Vermulst M, Weindruch R, Prolla TA. Effects of calorie restriction on the lifespan and healthspan of POLG mitochondrial mutator mice. Plos One. 12: e0171159. PMID 28158260 DOI: 10.1371/journal.pone.0171159  1
2016 Han C, Linser P, Park HJ, Kim MJ, White K, Vann JM, Ding D, Prolla TA, Someya S. Sirt1 deficiency protects cochlear cells and delays the early onset of age-related hearing loss in C57BL/6 mice. Neurobiology of Aging. 43: 58-71. PMID 27255815 DOI: 10.1016/j.neurobiolaging.2016.03.023  0.48
2016 Safdar A, Khrapko K, Flynn JM, Saleem A, Lisio M, Johnston APW, Kratysberg Y, Samjoo IA, Kitaoka Y, Ogborn DI, Little JP, Raha S, Parise G, Akhtar M, Hettinga BP, ... ... Prolla TA, et al. Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice Skeletal Muscle. DOI: 10.1186/s13395-016-0075-9  0.48
2015 Orogo AM, Gonzalez ER, Kubli DA, Baptista IL, Ong SB, Prolla TA, Sussman MA, Murphy AN, Gustafsson ÅB. Accumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and Reduces Survival. The Journal of Biological Chemistry. PMID 26183775 DOI: 10.1074/jbc.M115.649657  0.48
2015 Dittenhafer-Reed KE, Richards AL, Fan J, Smallegan MJ, Fotuhi Siahpirani A, Kemmerer ZA, Prolla TA, Roy S, Coon JJ, Denu JM. SIRT3 mediates multi-tissue coupling for metabolic fuel switching. Cell Metabolism. 21: 637-46. PMID 25863253 DOI: 10.1016/j.cmet.2015.03.007  0.48
2015 Barger JL, Anderson RM, Newton MA, da Silva C, Vann JA, Pugh TD, Someya S, Prolla TA, Weindruch R. A conserved transcriptional signature of delayed aging and reduced disease vulnerability is partially mediated by SIRT3. Plos One. 10: e0120738. PMID 25830335 DOI: 10.1371/journal.pone.0120738  0.48
2015 Li-Harms X, Milasta S, Lynch J, Wright C, Joshi A, Iyengar R, Neale G, Wang X, Wang YD, Prolla TA, Thompson JE, Opferman JT, Green DR, Schuetz J, Kundu M. Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice. Blood. 125: 162-74. PMID 25411424 DOI: 10.1182/blood-2014-07-586396  0.48
2014 Dai Y, Clark J, Zheng K, Kujoth GC, Prolla TA, Simon DK. Somatic mitochondrial DNA mutations do not increase neuronal vulnerability to MPTP in young POLG mutator mice. Neurotoxicology and Teratology. 46: 62-7. PMID 25450660 DOI: 10.1016/j.ntt.2014.10.004  0.48
2014 Hsu KT, Yu XM, Audhya AW, Jaume JC, Lloyd RV, Miyamoto S, Prolla TA, Chen H. Novel approaches in anaplastic thyroid cancer therapy. The Oncologist. 19: 1148-55. PMID 25260367 DOI: 10.1634/theoncologist.2014-0182  0.48
2014 Kukreja L, Kujoth GC, Prolla TA, Van Leuven F, Vassar R. Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer's disease. Molecular Neurodegeneration. 9: 16. PMID 24885175 DOI: 10.1186/1750-1326-9-16  0.48
2014 Prolla TA, Denu JM. NAD+ deficiency in age-related mitochondrial dysfunction. Cell Metabolism. 19: 178-80. PMID 24506863 DOI: 10.1016/j.cmet.2014.01.005  0.48
2014 Taylor SD, Ericson NG, Burton JN, Prolla TA, Silber JR, Shendure J, Bielas JH. Targeted enrichment and high-resolution digital profiling of mitochondrial DNA deletions in human brain Aging Cell. 13: 29-38. PMID 23911137 DOI: 10.1111/acel.12146  0.48
2013 Collino S, Martin FP, Montoliu I, Barger JL, Da Silva L, Prolla TA, Weindruch R, Kochhar S. Transcriptomics and Metabonomics Identify Essential Metabolic Signatures in Calorie Restriction (CR) Regulation across Multiple Mouse Strains. Metabolites. 3: 881-911. PMID 24958256 DOI: 10.3390/metabo3040881  1
2013 Joseph AM, Adhihetty PJ, Wawrzyniak NR, Wohlgemuth SE, Picca A, Kujoth GC, Prolla TA, Leeuwenburgh C. Dysregulation of mitochondrial quality control processes contribute to sarcopenia in a mouse model of premature aging. Plos One. 8: e69327. PMID 23935986 DOI: 10.1371/journal.pone.0069327  0.48
2013 Dai Y, Kiselak T, Clark J, Clore E, Zheng K, Cheng A, Kujoth GC, Prolla TA, Maratos-Flier E, Simon DK. Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice. Mitochondrion. 13: 282-91. PMID 23542163 DOI: 10.1016/j.mito.2013.03.006  0.48
2013 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, et al. Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome. Molecular Cell. 49: 186-99. PMID 23201123 DOI: 10.1016/j.molcel.2012.10.024  0.48
2012 Dillon LM, Hida A, Garcia S, Prolla TA, Moraes CT. Long-term bezafibrate treatment improves skin and spleen phenotypes of the mtDNA mutator mouse. Plos One. 7: e44335. PMID 22962610 DOI: 10.1371/journal.pone.0044335  0.48
2012 Dillon LM, Williams SL, Hida A, Peacock JD, Prolla TA, Lincoln J, Moraes CT. Increased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse. Human Molecular Genetics. 21: 2288-97. PMID 22357654 DOI: 10.1093/hmg/dds049  0.48
2012 Barger JL, Kayo T, Pugh TD, Vann JA, Power R, Dawson K, Weindruch R, Prolla TA. Gene expression profiling reveals differential effects of sodium selenite, selenomethionine, and yeast-derived selenium in the mouse. Genes & Nutrition. 7: 155-65. PMID 21847681 DOI: 10.1007/s12263-011-0243-9  0.48
2011 Fox R, Kim HS, Reddick RL, Kujoth GC, Prolla TA, Tsutsumi S, Wada Y, Smithies O, Maeda N. Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite. Proceedings of the National Academy of Sciences of the United States of America. 108: 8779-84. PMID 21555558 DOI: 10.1073/pnas.1106344108  0.48
2011 Safdar A, Bourgeois JM, Ogborn DI, Little JP, Hettinga BP, Akhtar M, Thompson JE, Melov S, Mocellin NJ, Kujoth GC, Prolla TA, Tarnopolsky MA. Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 4135-40. PMID 21368114 DOI: 10.1073/pnas.1019581108  0.48
2011 Dai DF, Johnson SC, Villarin JJ, Chin MT, Nieves-Cintrón M, Chen T, Marcinek DJ, Dorn GW, Kang YJ, Prolla TA, Santana LF, Rabinovitch PS. Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure. Circulation Research. 108: 837-46. PMID 21311045 DOI: 10.1161/CIRCRESAHA.110.232306  0.48
2011 Hallows WC, Yu W, Smith BC, Devries MK, Devires MK, Ellinger JJ, Someya S, Shortreed MR, Prolla T, Markley JL, Smith LM, Zhao S, Guan KL, Denu JM. Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Molecular Cell. 41: 139-49. PMID 21255725 DOI: 10.1016/j.molcel.2011.01.002  0.48
2011 Tomilov AA, Ramsey JJ, Hagopian K, Giorgio M, Kim KM, Lam A, Migliaccio E, Lloyd KC, Berniakovich I, Prolla TA, Pelicci P, Cortopassi GA. The Shc locus regulates insulin signaling and adiposity in mammals. Aging Cell. 10: 55-65. PMID 21040401 DOI: 10.1111/j.1474-9726.2010.00641.x  0.32
2010 Williams SL, Huang J, Edwards YJ, Ulloa RH, Dillon LM, Prolla TA, Vance JM, Moraes CT, Züchner S. The mtDNA mutation spectrum of the progeroid Polg mutator mouse includes abundant control region multimers. Cell Metabolism. 12: 675-82. PMID 21109200 DOI: 10.1016/j.cmet.2010.11.012  0.48
2010 Someya S, Yu W, Hallows WC, Xu J, Vann JM, Leeuwenburgh C, Tanokura M, Denu JM, Prolla TA. Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell. 143: 802-12. PMID 21094524 DOI: 10.1016/j.cell.2010.10.002  0.48
2010 Hiona A, Sanz A, Kujoth GC, Pamplona R, Seo AY, Hofer T, Someya S, Miyakawa T, Nakayama C, Samhan-Arias AK, Servais S, Barger JL, Portero-Otín M, Tanokura M, Prolla TA, et al. Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice. Plos One. 5: e11468. PMID 20628647 DOI: 10.1371/journal.pone.0011468  0.48
2010 Dai DF, Chen T, Wanagat J, Laflamme M, Marcinek DJ, Emond MJ, Ngo CP, Prolla TA, Rabinovitch PS. Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria. Aging Cell. 9: 536-44. PMID 20456298 DOI: 10.1111/j.1474-9726.2010.00581.x  0.48
2010 Xu J, Marzetti E, Seo AY, Kim JS, Prolla TA, Leeuwenburgh C. The emerging role of iron dyshomeostasis in the mitochondrial decay of aging. Mechanisms of Ageing and Development. 131: 487-93. PMID 20434480 DOI: 10.1016/j.mad.2010.04.007  0.48
2010 Someya S, Prolla TA. Mitochondrial oxidative damage and apoptosis in age-related hearing loss. Mechanisms of Ageing and Development. 131: 480-6. PMID 20434479 DOI: 10.1016/j.mad.2010.04.006  0.4
2010 Chen H, Vermulst M, Wang YE, Chomyn A, Prolla TA, McCaffery JM, Chan DC. Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations. Cell. 141: 280-9. PMID 20403324 DOI: 10.1016/j.cell.2010.02.026  0.48
2010 Someya S, Tanokura M, Weindruch R, Prolla TA, Yamasoba T. Effects of caloric restriction on age-related hearing loss in rodents and rhesus monkeys. Current Aging Science. 3: 20-5. PMID 20298166  1
2009 Someya S, Xu J, Kondo K, Ding D, Salvi RJ, Yamasoba T, Rabinovitch PS, Weindruch R, Leeuwenburgh C, Tanokura M, Prolla TA. Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 106: 19432-7. PMID 19901338 DOI: 10.1073/pnas.0908786106  0.48
2009 Chen ML, Logan TD, Hochberg ML, Shelat SG, Yu X, Wilding GE, Tan W, Kujoth GC, Prolla TA, Selak MA, Kundu M, Carroll M, Thompson JE. Erythroid dysplasia, megaloblastic anemia, and impaired lymphopoiesis arising from mitochondrial dysfunction. Blood. 114: 4045-53. PMID 19734452 DOI: 10.1182/blood-2008-08-169474  0.48
2009 Park SK, Kim K, Page GP, Allison DB, Weindruch R, Prolla TA. Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants. Aging Cell. 8: 484-95. PMID 19555370 DOI: 10.1111/j.1474-9726.2009.00496.x  1
2008 Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, ... Prolla TA, et al. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell. 135: 907-18. PMID 19041753 DOI: 10.1016/j.cell.2008.10.025  0.48
2008 Loerch PM, Lu T, Dakin KA, Vann JM, Isaacs A, Geula C, Wang J, Pan Y, Gabuzda DH, Li C, Prolla TA, Yankner BA. Evolution of the aging brain transcriptome and synaptic regulation. Plos One. 3: e3329. PMID 18830410 DOI: 10.1371/journal.pone.0003329  0.48
2008 Barger JL, Kayo T, Pugh TD, Prolla TA, Weindruch R. Short-term consumption of a resveratrol-containing nutraceutical mixture mimics gene expression of long-term caloric restriction in mouse heart Experimental Gerontology. 43: 859-866. PMID 18657603 DOI: 10.1016/j.exger.2008.06.013  0.48
2008 Barger JL, Kayo T, Vann JM, Arias EB, Wang J, Hacker TA, Wang Y, Raederstorff D, Morrow JD, Leeuwenburgh C, Allison DB, Saupe KW, Cartee GD, Weindruch R, Prolla TA. A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice. Plos One. 3: e2264. PMID 18523577 DOI: 10.1371/journal.pone.0002264  0.48
2008 Park SK, Page GP, Kim K, Allison DB, Meydani M, Weindruch R, Prolla TA. alpha- and gamma-Tocopherol prevent age-related transcriptional alterations in the heart and brain of mice. The Journal of Nutrition. 138: 1010-8. PMID 18492827 DOI: 10.1093/JN/138.6.1010  1
2008 Vermulst M, Wanagat J, Kujoth GC, Bielas JH, Rabinovitch PS, Prolla TA, Loeb LA. DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice Nature Genetics. 40: 392-394. PMID 18311139 DOI: 10.1038/ng.95  0.48
2008 Anderson RM, Barger JL, Edwards MG, Braun KH, O'Connor CE, Prolla TA, Weindruch R. Dynamic regulation of PGC-1alpha localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response. Aging Cell. 7: 101-11. PMID 18031569 DOI: 10.1111/j.1474-9726.2007.00357.x  0.48
2008 Someya S, Yamasoba T, Kujoth GC, Pugh TD, Weindruch R, Tanokura M, Prolla TA. The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase gamma. Neurobiology of Aging. 29: 1080-92. PMID 17363114 DOI: 10.1016/j.neurobiolaging.2007.01.014  1
2007 Someya S, Yamasoba T, Prolla TA, Tanokura M. Genes encoding mitochondrial respiratory chain components are profoundly down-regulated with aging in the cochlea of DBA/2J mice. Brain Research. 1182: 26-33. PMID 17964557 DOI: 10.1016/j.brainres.2007.08.090  0.4
2007 Edwards MG, Anderson RM, Yuan M, Kendziorski CM, Weindruch R, Prolla TA. Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program. Bmc Genomics. 8: 80. PMID 17381838 DOI: 10.1186/1471-2164-8-80  1
2007 Vermulst M, Bielas JH, Kujoth GC, Ladiges WC, Rabinovitch PS, Prolla TA, Loeb LA. Mitochondrial point mutations do not limit the natural lifespan of mice Nature Genetics. 39: 540-543. PMID 17334366 DOI: 10.1038/ng1988  0.48
2007 Sanz A, Hiona A, Kujoth GC, Seo AY, Hofer T, Kouwenhoven E, Kalani R, Prolla TA, Barja G, Leeuwenburgh C. Evaluation of sex differences on mitochondrial bioenergetics and apoptosis in mice Experimental Gerontology. 42: 173-182. PMID 17118599 DOI: 10.1016/j.exger.2006.10.003  0.48
2007 Megid WA, Ensenberger MG, Halberg RB, Stanhope SA, Kent-First MG, Prolla TA, Bacher JW. A novel method for biodosimetry. Radiation and Environmental Biophysics. 46: 147-54. PMID 17072633 DOI: 10.1007/s00411-006-0072-1  0.48
2007 Someya S, Yamasoba T, Weindruch R, Prolla TA, Tanokura M. Caloric restriction suppresses apoptotic cell death in the mammalian cochlea and leads to prevention of presbycusis. Neurobiology of Aging. 28: 1613-22. PMID 16890326 DOI: 10.1016/j.neurobiolaging.2006.06.024  1
2007 Yamasoba T, Someya S, Yamada C, Weindruch R, Prolla TA, Tanokura M. Role of mitochondrial dysfunction and mitochondrial DNA mutations in age-related hearing loss. Hearing Research. 226: 185-93. PMID 16870370 DOI: 10.1016/j.heares.2006.06.004  1
2006 Han SN, Adolfsson O, Lee CK, Prolla TA, Ordovas J, Meydani SN. Age and vitamin E-induced changes in gene expression profiles of T cells. Journal of Immunology (Baltimore, Md. : 1950). 177: 6052-61. PMID 17056531  0.48
2006 Haigis MC, Mostoslavsky R, Haigis KM, Fahie K, Christodoulou DC, Murphy AJ, Valenzuela DM, Yancopoulos GD, Karow M, Blander G, Wolberger C, Prolla TA, Weindruch R, Alt FW, Guarente L. SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell. 126: 941-54. PMID 16959573 DOI: 10.1016/j.cell.2006.06.057  0.48
2006 Kujoth GC, Leeuwenburgh C, Prolla TA. Mitochondrial DNA mutations and apoptosis in mammalian aging Cancer Research. 66: 7386-7389. PMID 16885331 DOI: 10.1158/0008-5472.CAN-05-4670  0.48
2006 Leeuwenburgh C, Prolla TA. Genetics, redox signaling, oxidative stress, and apoptosis in mammalian aging Antioxidants and Redox Signaling. 8: 503-505. PMID 16677094 DOI: 10.1089/ars.2006.8.503  0.48
2006 Higami Y, Barger JL, Page GP, Allison DB, Smith SR, Prolla TA, Weindruch R. Energy restriction lowers the expression of genes linked to inflammation, the cytoskeleton, the extracellular matrix, and angiogenesis in mouse adipose tissue. The Journal of Nutrition. 136: 343-52. PMID 16424110  0.48
2006 Hansen AB, Griner NB, Anderson JP, Kujoth GC, Prolla TA, Loeb LA, Glick E. Mitochondrial DNA integrity is not dependent on DNA polymerase-β activity Dna Repair. 5: 71-79. PMID 16165404 DOI: 10.1016/j.dnarep.2005.07.009  0.48
2005 Kujoth GC, Hiona A, Pugh TD, Someya S, Panzer K, Wohlgemuth SE, Hofer T, Seo AY, Sullivan R, Jobling WA, Morrow JD, Van Remmen H, Sedivy JM, Yamasoba T, Tanokura M, ... ... Prolla TA, et al. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science (New York, N.Y.). 309: 481-4. PMID 16020738 DOI: 10.1126/science.1112125  0.48
2005 Park SK, Prolla TA. Gene expression profiling studies of aging in cardiac and skeletal muscles. Cardiovascular Research. 66: 205-12. PMID 15820189 DOI: 10.1016/j.cardiores.2005.01.005  0.88
2005 Park SK, Prolla TA. Lessons learned from gene expression profile studies of aging and caloric restriction. Ageing Research Reviews. 4: 55-65. PMID 15619470 DOI: 10.1016/j.arr.2004.09.003  0.88
2004 Han SN, Adolfsson O, Lee CK, Prolla TA, Ordovas J, Meydani SN. Vitamin E and gene expression in immune cells. Annals of the New York Academy of Sciences. 1031: 96-101. PMID 15753137 DOI: 10.1196/annals.1331.010  0.48
2004 Bronikowski AM, Rhodes JS, Garland T, Prolla TA, Awad TA, Gammie SC. The evolution of gene expression in mouse hippocampus in response to selective breeding for increased locomotor activity. Evolution; International Journal of Organic Evolution. 58: 2079-86. PMID 15521463 DOI: 10.1111/J.0014-3820.2004.TB00491.X  0.48
2004 Edwards MG, Sarkar D, Klopp R, Morrow JD, Weindruch R, Prolla TA. Impairment of the transcriptional responses to oxidative stress in the heart of aged C57BL/6 mice. Annals of the New York Academy of Sciences. 1019: 85-95. PMID 15246999 DOI: 10.1196/annals.1297.017  1
2004 Spach KM, Pedersen LB, Nashold FE, Kayo T, Yandell BS, Prolla TA, Hayes CE. Gene expression analysis suggests that 1,25-dihydroxyvitamin D3 reverses experimental autoimmune encephalomyelitis by stimulating inflammatory cell apoptosis. Physiological Genomics. 18: 141-51. PMID 15138306 DOI: 10.1152/physiolgenomics.00003.2004  0.48
2004 Lee CK, Pugh TD, Klopp RG, Edwards J, Allison DB, Weindruch R, Prolla TA. The impact of alpha-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice. Free Radical Biology & Medicine. 36: 1043-57. PMID 15059645 DOI: 10.1016/j.freeradbiomed.2004.01.015  1
2004 Higami Y, Pugh TD, Page GP, Allison DB, Prolla TA, Weindruch R. Adipose tissue energy metabolism: altered gene expression profile of mice subjected to long-term caloric restriction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 415-7. PMID 14688200 DOI: 10.1096/fj.03-0678fje  1
2004 Gadbury GL, Page GP, Edwards J, Kayo T, Prolla TA, Weindruch R, Permana PA, Mountz JD, Allison DB. Power and sample size estimation in high dimensional biology Statistical Methods in Medical Research. 13: 325-338.  0.48
2003 Edwards MG, Sarkar D, Klopp R, Morrow JD, Weindruch R, Prolla TA. Age-related impairment of the transcriptional responses to oxidative stress in the mouse heart. Physiological Genomics. 13: 119-27. PMID 12595580 DOI: 10.1152/physiolgenomics.00172.2002  1
2003 Bronikowski AM, Carter PA, Morgan TJ, Garland T, Ung N, Pugh TD, Weindruch R, Prolla TA. Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart. Physiological Genomics. 12: 129-38. PMID 12429864 DOI: 10.1152/physiolgenomics.00082.2002  0.48
2002 Weindruch R, Kayo T, Lee CK, Prolla TA. Effects of caloric restriction on gene expression. Nestlé Nutrition Workshop Series. Clinical & Performance Programme. 6: 17-28; discussion 28. PMID 16969964  1
2002 Weindruch R, Prolla TA. Gene expression profile of the aging brain. Archives of Neurology. 59: 1712-4. PMID 12433256  1
2002 Lee CK, Allison DB, Brand J, Weindruch R, Prolla TA. Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts. Proceedings of the National Academy of Sciences of the United States of America. 99: 14988-93. PMID 12419851 DOI: 10.1073/pnas.232308999  1
2002 Weindruch R, Kayo T, Lee CK, Prolla TA. Gene expression profiling of aging using DNA microarrays. Mechanisms of Ageing and Development. 123: 177-93. PMID 11718811  1
2001 Lee CK, Prolla TA, Weindruch R. Caloric Intake, Oxidative Stress and Aging. Thescientificworldjournal. 1: 85. PMID 30147557 DOI: 10.1100/tsw.2001.117  1
2001 Kayo T, Allison DB, Weindruch R, Prolla TA. Influences of aging and caloric restriction on the transcriptional profile of skeletal muscle from rhesus monkeys. Proceedings of the National Academy of Sciences of the United States of America. 98: 5093-8. PMID 11309484 DOI: 10.1073/PNAS.081061898  0.32
2001 Weindruch R, Kayo T, Lee CK, Prolla TA. Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice. The Journal of Nutrition. 131: 918S-923S. PMID 11238786  1
2000 Lee CK, Weindruch R, Prolla TA. Gene-expression profile of the ageing brain in mice. Nature Genetics. 25: 294-7. PMID 10888876 DOI: 10.1038/77046  1
1999 Lee CK, Klopp RG, Weindruch R, Prolla TA. Gene expression profile of aging and its retardation by caloric restriction. Science (New York, N.Y.). 285: 1390-3. PMID 10464095  1
1999 Yao X, Buermeyer AB, Narayanan L, Tran D, Baker SM, Prolla TA, Glazer PM, Liskay RM, Arnheim N. Different mutator phenotypes in Mlh1- versus Pms2-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 6850-5. PMID 10359802 DOI: 10.1073/pnas.96.12.6850  0.48
1998 Prolla TA, Baker SM, Harris AC, Tsao JL, Yao X, Bronner CE, Zheng B, Gordon M, Reneker J, Arnheim N, Shibata D, Bradley A, Liskay RM. Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair. Nature Genetics. 18: 276-9. PMID 9500552 DOI: 10.1038/ng0398-276  0.48
1996 Baker SM, Plug AW, Prolla TA, Bronner CE, Harris AC, Yao X, Christie DM, Monell C, Arnheim N, Bradley A, Ashley T, Liskay RM. Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over. Nature Genetics. 13: 336-42. PMID 8673133 DOI: 10.1038/ng0796-336  0.48
1994 Prolla TA, Pang Q, Alani E, Kolodner RD, Liskay RM. MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast Science. 265: 1091-1093. PMID 8066446  0.48
1993 Strand M, Prolla TA, Liskay RM, Petes TD. Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair Nature. 365: 274-276. PMID 8371783 DOI: 10.1038/365274a0  0.48
1991 Gruetter R, Prolla TA, Shulman RG. 13C NMR visibility of rabbit muscle glycogen in vivo. Magnetic Resonance in Medicine. 20: 327-32. PMID 1775059 DOI: 10.1002/mrm.1910200216  0.48
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