Van Luu-The - Publications

Affiliations: 
Universite Laval (Canada) 
Area:
Molecular Biology, Animal Physiology Biology

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Tchernof A, Lin SX, Luu-The V, Simard J. The Passing of Dr. Fernand Labrie (1937-2019): The legacy of excellence in science. The Journal of Steroid Biochemistry and Molecular Biology. PMID 30779933 DOI: 10.1016/J.Jsbmb.2019.02.005  0.32
2015 Mansour MF, Pelletier M, Boulet MM, Mayrand D, Brochu G, Lebel S, Poirier D, Fradette J, Cianflone K, Luu-The V, Tchernof A. Oxidative activity of 17β-hydroxysteroid dehydrogenase on testosterone in male abdominal adipose tissues and cellular localization of 17β-HSD type 2. Molecular and Cellular Endocrinology. PMID 26123590 DOI: 10.1016/J.Mce.2015.06.016  0.84
2015 Tchernof A, Mansour MF, Pelletier M, Boulet MM, Nadeau M, Luu-The V. Updated survey of the steroid-converting enzymes in human adipose tissues. The Journal of Steroid Biochemistry and Molecular Biology. 147: 56-69. PMID 25448733 DOI: 10.1016/J.Jsbmb.2014.11.011  0.84
2013 Burel D, Li JH, Do-Rego JL, Wang AF, Luu-The V, Pelletier G, Tillet Y, Taragnat C, Kwon HB, Seong JY, Vaudry H. Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus. Endocrinology. 154: 2114-28. PMID 23554453 DOI: 10.1210/En.2013-1095  0.84
2013 Morisset AS, Dubé MC, Drolet R, Pelletier M, Labrie F, Luu-The V, Tremblay Y, Robitaille J, John Weisnagel S, Tchernof A. Androgens in the maternal and fetal circulation: association with insulin resistance. The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 26: 513-9. PMID 23075231 DOI: 10.3109/14767058.2012.735725  0.84
2012 Calvo E, Luu-The V, Belleau P, Martel C, Labrie F. Specific transcriptional response of four blockers of estrogen receptors on estradiol-modulated genes in the mouse mammary gland. Breast Cancer Research and Treatment. 134: 625-47. PMID 22678160 DOI: 10.1007/S10549-012-2104-7  0.6
2012 Do Rego JL, Seong JY, Burel D, Leprince J, Vaudry D, Luu-The V, Tonon MC, Tsutsui K, Pelletier G, Vaudry H. Regulation of neurosteroid biosynthesis by neurotransmitters and neuropeptides. Frontiers in Endocrinology. 3: 4. PMID 22654849 DOI: 10.3389/Fendo.2012.00004  0.84
2012 Veilleux A, Côté JA, Blouin K, Nadeau M, Pelletier M, Marceau P, Laberge PY, Luu-The V, Tchernof A. Glucocorticoid-induced androgen inactivation by aldo-keto reductase 1C2 promotes adipogenesis in human preadipocytes. American Journal of Physiology. Endocrinology and Metabolism. 302: E941-9. PMID 22275760 DOI: 10.1152/Ajpendo.00069.2011  0.84
2012 Calvo E, Luu-The V, Martel C, Labrie F. Antagonistic activity of acolbifene, fulvestrant, tamoxifen, and raloxifene on cancer-associated genes in the mouse mammary gland. Journal of Clinical Oncology. 30: 10583-10583. DOI: 10.1200/Jco.2012.30.15_Suppl.10583  0.6
2012 Calvo E, Luu-The V, Martel C, Labrie F. Abstract P2-06-03: Specific Transcriptional Response of Four Blockers of Estrogen Receptors on Estrogen-Modulated Genes in ZR-75-1 Breast Cancer Xenografts Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P2-06-03  0.6
2011 Vaudry H, Do Rego JL, Burel D, Luu-The V, Pelletier G, Vaudry D, Tsutsui K. Neurosteroid biosynthesis in the brain of amphibians. Frontiers in Endocrinology. 2: 79. PMID 22649387 DOI: 10.3389/Fendo.2011.00079  0.84
2011 Lu L, Zhao G, Luu-The V, Ouellet J, Fan Z, Labrie F, Pelletier G. Expression of 11β-hydroxysteroid dehydrogenase type 1 in breast cancer and adjacent non-malignant tissue. An immunocytochemical study. Pathology Oncology Research : Por. 17: 627-32. PMID 21267686 DOI: 10.1007/S12253-011-9361-3  0.84
2010 Samson M, Labrie F, Luu-The V. Sequential transformation of 4-androstenedione into dihydrotestosterone in prostate carcinoma (DU-145) cells indicates that 4-androstenedione and not testosterone is the substrate of 5α-reductase. Hormone Molecular Biology and Clinical Investigation. 1: 67-72. PMID 25961972 DOI: 10.1515/Hmbci.2010.009  0.6
2010 Zhao G, Lu L, Luu-The V, Fan Z, Labrie F, Pelletier G. Expression of 5α-reductase type 1 in breast cancer and adjacent non-malignant tissue: an immunohistochemical study. Hormone Molecular Biology and Clinical Investigation. 3: 411-5. PMID 25961212 DOI: 10.1515/Hmbci.2010.046  0.6
2010 Yamana K, Labrie F, Luu-The V. Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride. Hormone Molecular Biology and Clinical Investigation. 2: 293-9. PMID 25961201 DOI: 10.1515/Hmbci.2010.035  0.6
2010 Luu-The V, Labrie F. The intracrine sex steroid biosynthesis pathways. Progress in Brain Research. 181: 177-92. PMID 20478438 DOI: 10.1016/S0079-6123(08)81010-2  0.6
2010 Samson M, Labrie F, Zouboulis CC, Luu-The V. Biosynthesis of dihydrotestosterone by a pathway that does not require testosterone as an intermediate in the SZ95 sebaceous gland cell line. The Journal of Investigative Dermatology. 130: 602-4. PMID 19812596 DOI: 10.1038/Jid.2009.225  0.6
2010 Bruzzone F, Do Rego JL, Luu-The V, Pelletier G, Vallarino M, Vaudry H. Immunohistochemical localization and biological activity of 3beta-hydroxysteroid dehydrogenase and 5alpha-reductase in the brain of the frog, Rana esculenta, during development. Journal of Chemical Neuroanatomy. 39: 35-50. PMID 19665548 DOI: 10.1016/J.Jchemneu.2009.08.001  0.32
2010 Blouin K, Nadeau M, Perreault M, Veilleux A, Drolet R, Marceau P, Mailloux J, Luu-The V, Tchernof A. Effects of androgens on adipocyte differentiation and adipose tissue explant metabolism in men and women. Clinical Endocrinology. 72: 176-88. PMID 19500113 DOI: 10.1111/J.1365-2265.2009.03645.X  0.84
2009 Poisson Paré D, Song D, Luu-The V, Han B, Li S, Liu G, Labrie F, Pelletier G. Expression of Estrogen Sulfotransferase 1E1 and Steroid Sulfatase in Breast Cancer: A Immunohistochemical Study. Breast Cancer : Basic and Clinical Research. 3: 9-21. PMID 21556246 DOI: 10.4137/BCBCR.S2012  0.6
2009 Bellavance E, Luu-The V, Poirier D. Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. Journal of Medicinal Chemistry. 52: 7488-502. PMID 19772289 DOI: 10.1021/Jm900921C  0.84
2009 Do Rego JL, Seong JY, Burel D, Leprince J, Luu-The V, Tsutsui K, Tonon MC, Pelletier G, Vaudry H. Neurosteroid biosynthesis: enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides. Frontiers in Neuroendocrinology. 30: 259-301. PMID 19505496 DOI: 10.1016/J.Yfrne.2009.05.006  0.32
2009 Luu-The V, Duche D, Ferraris C, Meunier JR, Leclaire J, Labrie F. Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models Episkin and full thickness model from Episkin. The Journal of Steroid Biochemistry and Molecular Biology. 116: 178-86. PMID 19482084 DOI: 10.1016/j.jsbmb.2009.05.011  0.6
2009 Samson M, Labrie F, Luu-The V. Specific estradiol biosynthetic pathway in choriocarcinoma (JEG-3) cell line. The Journal of Steroid Biochemistry and Molecular Biology. 116: 154-9. PMID 19465125 DOI: 10.1016/J.Jsbmb.2009.05.009  0.6
2009 Cevasco A, Pittaluga A, Do Rego JL, Luu-The V, Pelletier G, Vaudry H, Mandich A. Immunohistochemical localization of hydroxysteroid sulfotransferase and sulfatase in the brain of Rana esculenta tadpoles. Annals of the New York Academy of Sciences. 1163: 365-8. PMID 19456361 DOI: 10.1111/J.1749-6632.2009.04436.X  0.32
2009 Do Rego JL, Seong JY, Burel D, Luu-The V, Larhammar D, Tsutsui K, Pelletier G, Tonon MC, Vaudry H. Steroid biosynthesis within the frog brain: a model of neuroendocrine regulation. Annals of the New York Academy of Sciences. 1163: 83-92. PMID 19456330 DOI: 10.1111/J.1749-6632.2008.03664.X  0.32
2009 Li Z, Luu-The V, Poisson-Paré D, Ouellet J, Li S, Labrie F, Pelletier G. Expression of enzymes involved in synthesis and metabolism of estradiol in human breast as studied by immunocytochemistry and in situ hybridization. Histology and Histopathology. 24: 273-82. PMID 19130396 DOI: 10.14670/Hh-24.273  0.84
2009 Zhang Y, Nadeau M, Faucher F, Lescelleur O, Biron S, Daris M, Rhéaume C, Luu-The V, Tchernof A. Progesterone metabolism in adipose cells. Molecular and Cellular Endocrinology. 298: 76-83. PMID 18984031 DOI: 10.1016/J.Mce.2008.09.034  0.36
2009 Bydal P, Luu-The V, Labrie F, Poirier D. Steroidal lactones as inhibitors of 17beta-hydroxysteroid dehydrogenase type 5: chemical synthesis, enzyme inhibitory activity, and assessment of estrogenic and androgenic activities. European Journal of Medicinal Chemistry. 44: 632-44. PMID 18472187 DOI: 10.1016/J.Ejmech.2008.03.020  0.6
2008 Faucher F, Cantin L, Luu-The V, Labrie F, Breton R. Crystal structures of human Δ4-3-ketosteroid 5β-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition Biochemistry. 47: 13537-13546. PMID 19075558 DOI: 10.1021/Bi801276H  0.6
2008 Calvo E, Luu-The V, Morissette J, Martel C, Labrie C, Bernard B, Bernerd F, Deloche C, Chaussade V, Leclaire J, Labrie F. Pangenomic changes induced by DHEA in the skin of postmenopausal women. The Journal of Steroid Biochemistry and Molecular Biology. 112: 186-93. PMID 19013239 DOI: 10.1016/J.Jsbmb.2008.10.008  0.84
2008 Han B, Li S, Song D, Poisson-Paré D, Liu G, Luu-The V, Ouellet J, Li S, Labrie F, Pelletier G. Expression of 17beta-hydroxysteroid dehydrogenase type 2 and type 5 in breast cancer and adjacent non-malignant tissue: a correlation to clinicopathological parameters. The Journal of Steroid Biochemistry and Molecular Biology. 112: 194-200. PMID 18996480 DOI: 10.1016/J.Jsbmb.2008.10.004  0.6
2008 Zhang Y, Calvo E, Martel C, Luu-The V, Labrie F, Tchernof A. Response of the adipose tissue transcriptome to dihydrotestosterone in mice. Physiological Genomics. 35: 254-61. PMID 18728228 DOI: 10.1152/Physiolgenomics.00257.2007  0.6
2008 Faucher F, Cantin L, Luu-The V, Labrie F, Breton R. The crystal structure of human Δ4-3-ketosteroid 5β-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism Biochemistry. 47: 8261-8270. PMID 18624455 DOI: 10.1021/Bi800572S  0.6
2008 Luu-The V, Bélanger A, Labrie F. Androgen biosynthetic pathways in the human prostate. Best Practice & Research. Clinical Endocrinology & Metabolism. 22: 207-21. PMID 18471780 DOI: 10.1016/J.Beem.2008.01.008  0.6
2007 Tenta R, Katopodis H, Chatziioannou A, Pilalis E, Calvo E, Luu-The V, Labrie F, Kolisis F, Koutsilieris M. Microarray analysis of survival pathways in human PC-3 prostate cancer cells. Cancer Genomics & Proteomics. 4: 309-18. PMID 17878531  0.6
2007 Luu-The V, Ferraris C, Duche D, Bélanger P, Leclaire J, Labrie F. Steroid metabolism and profile of steroidogenic gene expression in Episkin: high similarity with human epidermis. The Journal of Steroid Biochemistry and Molecular Biology. 107: 30-6. PMID 17662597 DOI: 10.1016/J.Jsbmb.2007.03.036  0.6
2007 Rego JL, Leprince J, Luu-The V, Pelletier G, Tonon MC, Vaudry H. Structure-activity relationships of a series of analogs of the endozepine octadecaneuropeptide (ODN(11)(-)(18)) on neurosteroid biosynthesis by hypothalamic explants. Journal of Medicinal Chemistry. 50: 3070-6. PMID 17550241 DOI: 10.1021/Jm0610548  0.32
2007 Faucher F, Cantin L, Pereira de Jésus-Tran K, Lemieux M, Luu-The V, Labrie F, Breton R. Mouse 17α-Hydroxysteroid Dehydrogenase (AKR1C21) Binds Steroids Differently from other Aldo-keto Reductases: Identification and Characterization of Amino Acid Residues Critical for Substrate Binding Journal of Molecular Biology. 369: 525-540. PMID 17442338 DOI: 10.1016/J.Jmb.2007.03.058  0.6
2007 Ivanga M, Labrie Y, Calvo E, Belleau P, Martel C, Luu-The V, Morissette J, Labrie F, Durocher F. Temporal analysis of E2 transcriptional induction of PTP and MKP and downregulation of IGF-I pathway key components in the mouse uterus. Physiological Genomics. 29: 13-23. PMID 17361005 DOI: 10.1152/Physiolgenomics.00291.2005  0.84
2007 Liu H, Zheng S, Bellemare V, Pelletier G, Labrie F, Luu-The V. Expression and localization of estrogenic type 12 17beta-hydroxysteroid dehydrogenase in the cynomolgus monkey. Bmc Biochemistry. 8: 2. PMID 17280614 DOI: 10.1186/1471-2091-8-2  0.6
2007 Liu H, Bellemare V, Labrie F, Luu-The V. Molecular characterization of the cynomolgus monkey Macaca fascicularis steroidogenic enzymes belonging to the aldo-keto reductase family. The Journal of Steroid Biochemistry and Molecular Biology. 104: 75-80. PMID 17257829 DOI: 10.1016/J.Jsbmb.2006.10.004  0.6
2007 Qiu W, Zhou M, Mazumdar M, Azzi A, Ghanmi D, Luu-The V, Labrie F, Lin SX. Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase. The Journal of Biological Chemistry. 282: 8368-79. PMID 17166832 DOI: 10.1074/Jbc.M606784200  0.6
2007 Cadot C, Laplante Y, Kamal F, Luu-The V, Poirier D. C6-(N,N-butyl-methyl-heptanamide) derivatives of estrone and estradiol as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: Chemical synthesis and biological evaluation. Bioorganic & Medicinal Chemistry. 15: 714-26. PMID 17110114 DOI: 10.1016/J.Bmc.2006.10.055  0.84
2007 Do Rego JL, Tremblay Y, Luu-The V, Repetto E, Castel H, Vallarino M, Bélanger A, Pelletier G, Vaudry H. Immunohistochemical localization and biological activity of the steroidogenic enzyme cytochrome P450 17alpha-hydroxylase/C17, 20-lyase (P450C17) in the frog brain and pituitary. Journal of Neurochemistry. 100: 251-68. PMID 17076760 DOI: 10.1111/J.1471-4159.2006.04209.X  0.32
2006 Faucher F, Pereira de Jésus-Tran K, Cantin L, Luu-The V, Labrie F, Breton R. Crystal Structures of Mouse 17α-Hydroxysteroid Dehydrogenase (Apoenzyme and Enzyme-NADP(H) Binary Complex): Identification of Molecular Determinants Responsible for the Unique 17α-reductive Activity of this Enzyme Journal of Molecular Biology. 364: 747-763. PMID 17034817 DOI: 10.1016/J.Jmb.2006.09.030  0.6
2006 Labrie F, Luu-The V, Martel C, Chernomoretz A, Calvo E, Morissette J, Labrie C. Dehydroepiandrosterone (DHEA) is an anabolic steroid like dihydrotestosterone (DHT), the most potent natural androgen, and tetrahydrogestrinone (THG). The Journal of Steroid Biochemistry and Molecular Biology. 100: 52-8. PMID 16797178 DOI: 10.1016/J.Jsbmb.2006.03.006  0.84
2006 Do-Rego JL, Acharjee S, Seong JY, Galas L, Alexandre D, Bizet P, Burlet A, Kwon HB, Luu-The V, Pelletier G, Vaudry H. Vasotocin and mesotocin stimulate the biosynthesis of neurosteroids in the frog brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6749-60. PMID 16793882 DOI: 10.1523/Jneurosci.4469-05.2006  0.32
2006 Paradis ME, Badellino KO, Rader DJ, Tchernof A, Richard C, Luu-The V, Deshaies Y, Bergeron J, Archer WR, Couture P, Bergeron N, Lamarche B. Visceral adiposity and endothelial lipase. The Journal of Clinical Endocrinology and Metabolism. 91: 3538-43. PMID 16772345 DOI: 10.1210/Jc.2006-0766  0.84
2006 Takase Y, Lévesque MH, Luu-The V, El-Alfy M, Labrie F, Pelletier G. Expression of enzymes involved in estrogen metabolism in human prostate. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 54: 911-21. PMID 16651392 DOI: 10.1369/Jhc.6A6927.2006  0.6
2006 Ngatcha BT, Laplante Y, Labrie F, Luu-The V, Poirier D. 3Beta-alkyl-androsterones as inhibitors of type 3 17beta-hydroxysteroid dehydrogenase: inhibitory potency in intact cells, selectivity towards isoforms 1, 2, 5 and 7, binding affinity for steroid receptors, and proliferative/antiproliferative activities on AR+ and ER+ cell lines. Molecular and Cellular Endocrinology. 248: 225-32. PMID 16359782 DOI: 10.1016/J.Mce.2005.10.023  0.6
2006 Bellemare V, Labrie F, Luu-The V. Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues. The Journal of Steroid Biochemistry and Molecular Biology. 98: 18-24. PMID 16191478 DOI: 10.1016/J.Jsbmb.2005.07.004  0.6
2006 Luu-The V, Tremblay P, Labrie F. Characterization of type 12 17beta-hydroxysteroid dehydrogenase, an isoform of type 3 17beta-hydroxysteroid dehydrogenase responsible for estradiol formation in women. Molecular Endocrinology (Baltimore, Md.). 20: 437-43. PMID 16166196 DOI: 10.1210/Me.2005-0058  0.6
2006 Rego JLD, Acharjee S, Galas L, Alexandre D, Bizet P, Kwon HB, Burlet A, Luu-The V, Pelletier G, Seong JY, Vaudry H. Vasotocin and mesotocin stimulate neurosteroid biosynthesis in the frog brain. Possible involvement of a V1a receptor Frontiers in Neuroendocrinology. 27: 115-116. DOI: 10.1016/J.Yfrne.2006.03.298  0.32
2005 Labrie F, Luu-The V, Bélanger A, Lin SX, Simard J, Pelletier G, Labrie C. Is dehydroepiandrosterone a hormone? The Journal of Endocrinology. 187: 169-96. PMID 16293766 DOI: 10.1677/Joe.1.06264  0.6
2005 Tchédam Ngatcha B, Luu-The V, Labrie F, Poirier D. Androsterone 3alpha-ether-3beta-substituted and androsterone 3beta-substituted derivatives as inhibitors of type 3 17beta-hydroxysteroid dehydrogenase: chemical synthesis and structure-activity relationship. Journal of Medicinal Chemistry. 48: 5257-68. PMID 16078844 DOI: 10.1021/Jm058179H  0.6
2005 Couture JF, de Jésus-Tran KP, Roy AM, Cantin L, Côté PL, Legrand P, Luu-The V, Labrie F, Breton R. Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen. Protein Science : a Publication of the Protein Society. 14: 1485-97. PMID 15929998 DOI: 10.1110/Ps.051353205  0.6
2005 Pelletier G, Luu-The V, Li S, Labrie F. Localization of type 8 17beta-hydroxysteroid dehydrogenase mRNA in mouse tissues as studied by in situ hybridization. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 1257-71. PMID 15923359 DOI: 10.1369/Jhc.5A6692.2005  0.6
2005 Vallarino M, Mathieu M, do-Rego JL, Bruzzone F, Chartrel N, Luu-The V, Pelletier G, Vaudry H. Ontogeny of 3 beta-hydroxysteroid dehydrogenase and 5 alpha-reductase in the frog brain. Annals of the New York Academy of Sciences. 1040: 490-3. PMID 15891098 DOI: 10.1196/Annals.1327.100  0.32
2005 Labrie F, Bélanger A, Luu-The V, Labrie C, Simard J, Cusan L, Gomez J, Candas B. Gonadotropin-releasing hormone agonists in the treatment of prostate cancer. Endocrine Reviews. 26: 361-79. PMID 15867098 DOI: 10.1210/Er.2004-0017  0.6
2005 Samson M, Labrie F, Luu-The V. Inhibition of human-type 1 3beta-hydroxysteroid deshydrogenase/Delta(5)-Delta(4)-isomerase expression using siRNA. The Journal of Steroid Biochemistry and Molecular Biology. 94: 253-7. PMID 15862972 DOI: 10.1016/J.Jsbmb.2005.01.011  0.6
2005 Luu-The V, Pelletier G, Labrie F. Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase. The Journal of Steroid Biochemistry and Molecular Biology. 93: 269-76. PMID 15860270 DOI: 10.1016/J.Jsbmb.2005.01.003  0.6
2005 Pelletier G, Luu-The V, Li S, Labrie F. Localization of type 5 17β-hydroxysteroid dehydrogenase mRNA in mouse tissues as studied by in situ hybridization Cell and Tissue Research. 320: 393-398. PMID 15846505 DOI: 10.1007/S00441-005-1105-9  0.6
2005 Luu-The V, Paquet N, Calvo E, Cumps J. Improved real-time RT-PCR method for high-throughput measurements using second derivative calculation and double correction. Biotechniques. 38: 287-93. PMID 15727135 DOI: 10.2144/05382Rr05  0.44
2005 Labrie F, Luu-The V, Calvo E, Martel C, Cloutier J, Gauthier S, Belleau P, Morissette J, Lévesque MH, Labrie C. Tetrahydrogestrinone induces a genomic signature typical of a potent anabolic steroid. The Journal of Endocrinology. 184: 427-33. PMID 15684350 DOI: 10.1677/Joe.1.05997  0.84
2004 Labrie F, Cusan L, Gomez J, Luu-The V, Candas B, Bélanger A, Labrie C. Major impact of hormonal therapy in localized prostate cancer--death can already be an exception. The Journal of Steroid Biochemistry and Molecular Biology. 92: 327-44. PMID 15698538 DOI: 10.1016/J.Jsbmb.2004.10.011  0.6
2004 Pelletier G, Luu-The V, Li S, Ouellet J, Labrie F. Cellular localization of mRNA expression of enzymes involved in the formation and inactivation of hormonal steroids in the mouse prostate. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 52: 1351-6. PMID 15385581 DOI: 10.1177/002215540405201011  0.6
2004 Couture JF, Legrand P, Cantin L, Labrie F, Luu-The V, Breton R. Loop relaxation, A mechanism that explains the reduced specificity of rabbit 20α-hydroxysteroid dehydrogenase, A member of the aldo-keto reductase superfamily Journal of Molecular Biology. 339: 89-102. PMID 15123423 DOI: 10.1016/J.Jmb.2004.03.035  0.6
2004 Gizard F, Teissier E, Dufort I, Luc G, Luu-The V, Staels B, Hum DW. The transcriptional regulating protein of 132 kDa (TReP-132) differentially influences steroidogenic pathways in human adrenal NCI-H295 cells. Journal of Molecular Endocrinology. 32: 557-69. PMID 15072559 DOI: 10.1677/Jme.0.0320557  0.8
2003 Labrie F, Cusan L, Gomez JL, Candas B, Bélanger A, Luu-The V, Labrie C, Simard J. [From the gene to the clinic: prostate cancer death can now be an exception?]. Mã©Decine Sciences : M/S. 19: 910-9. PMID 14612999 DOI: 10.1051/Medsci/20031910910  0.6
2003 Ciobanu LC, Luu-The V, Martel C, Labrie F, Poirier D. Inhibition of estrone sulfate-induced uterine growth by potent nonestrogenic steroidal inhibitors of steroid sulfatase. Cancer Research. 63: 6442-6. PMID 14559834  0.84
2003 Couture JF, Legrand P, Cantin L, Luu-The V, Labrie F, Breton R. Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids. Journal of Molecular Biology. 331: 593-604. PMID 12899831 DOI: 10.1016/S0022-2836(03)00762-9  0.6
2003 Labrie F, Luu-The V, Labrie C, Bélanger A, Simard J, Lin SX, Pelletier G. Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocrine Reviews. 24: 152-82. PMID 12700178 DOI: 10.1210/Er.2001-0031  0.6
2003 Soucy P, Lacoste L, Luu-The V. Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor. Role of recombinant cytochrome b5 and P450 reductase. European Journal of Biochemistry / Febs. 270: 1349-55. PMID 12631293 DOI: 10.1046/J.1432-1033.2003.03508.X  0.84
2002 Beaujean D, Do-Rego JL, Galas L, Mensah-Nyagan AG, Fredriksson R, Larhammar D, Fournier A, Luu-The V, Pelletier G, Vaudry H. Neuropeptide Y Inhibits the Biosynthesis of Sulfated Neurosteroids in the Hypothalamus through Activation of Y1 Receptors. Endocrinology. 143: 1950-1963. PMID 28204420 DOI: 10.1210/endo.143.5.8765  0.32
2002 Tchédam-Ngatcha B, Luu-The V, Poirier D. Androsterone derivatives substituted at position 16: chemical synthesis, inhibition of type 3 17beta-hydroxysteroid dehydrogenase, binding affinity for steroid receptors and proliferative/antiproliferative activity on Shionogi (AR+) cells. Journal of Enzyme Inhibition and Medicinal Chemistry. 17: 155-65. PMID 12443041 DOI: 10.1080/1475636021000002067  0.84
2002 Faucher F, Lacoste L, Luu-The V. Human type 1 estrogen sulfotransferase: catecholestrogen metabolism and potential involvement in cancer promotion. Annals of the New York Academy of Sciences. 963: 221-8. PMID 12095948  0.56
2002 Beaujean D, Do-Rego JL, Galas L, Mensah-Nyagan AG, Fredriksson R, Larhammar D, Fournier A, Luu-The V, Pelletier G, Vaudry H. Neuropeptide Y inhibits the biosynthesis of sulfated neurosteroids in the hypothalamus through activation of Y(1) receptors. Endocrinology. 143: 1950-63. PMID 11956178 DOI: 10.1210/Endo.143.5.8765  0.32
2002 Ciobanu LC, Luu-The V, Poirier D. Nonsteroidal compounds designed to mimic potent steroid sulfatase inhibitors. The Journal of Steroid Biochemistry and Molecular Biology. 80: 339-53. PMID 11948019 DOI: 10.1016/S0960-0760(02)00024-9  0.84
2002 Soucy P, Luu-The V. Assessment of the ability of type 2 cytochrome b5 to modulate 17,20-lyase activity of human P450c17. The Journal of Steroid Biochemistry and Molecular Biology. 80: 71-5. PMID 11867265 DOI: 10.1016/S0960-0760(01)00171-6  0.84
2002 Maltais R, Luu-The V, Poirier D. Synthesis and optimization of a new family of type 3 17 beta-hydroxysteroid dehydrogenase inhibitors by parallel liquid-phase chemistry. Journal of Medicinal Chemistry. 45: 640-53. PMID 11806715 DOI: 10.1021/Jm010286Y  0.84
2002 Couture JF, Cantin L, Legrand P, Luu-The V, Labrie F, Breton R. Expression, crystallization and preliminary X-ray analysis of human and rabbit 20alpha-hydroxysteroid dehydrogenases in complex with NADP(H) and various steroid substrates. Acta Crystallographica. Section D, Biological Crystallography. 58: 135-9. PMID 11752791 DOI: 10.1107/S0907444901017346  0.6
2001 Maltais R, Luu-The V, Poirier D. Parallel solid-phase synthesis of 3β-peptido-3α-hydroxy-5α-androstan-17-one derivatives for inhibition of Type 3 17β-hydroxysteroid dehydrogenase Bioorganic and Medicinal Chemistry. 9: 3101-3111. PMID 11711285 DOI: 10.1016/S0968-0896(01)00182-1  0.84
2001 Pelletier G, Li S, Luu-The V, Tremblay Y, Bélanger A, Labrie F. Immunoelectron microscopic localization of three key steroidogenic enzymes (cytochrome P450(scc), 3 beta-hydroxysteroid dehydrogenase and cytochrome P450(c17)) in rat adrenal cortex and gonads. The Journal of Endocrinology. 171: 373-83. PMID 11691658 DOI: 10.1677/Joe.0.1710373  0.6
2001 Nahoum V, Gangloff A, Legrand P, Zhu DW, Cantin L, Zhorov BS, Luu-The V, Labrie F, Breton R, Lin SX. Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution. The Journal of Biological Chemistry. 276: 42091-8. PMID 11514561 DOI: 10.1074/Jbc.M105610200  0.6
2001 Dufort I, Soucy P, Lacoste L, Luu-The V. Comparative biosynthetic pathway of androstenol and androgens. The Journal of Steroid Biochemistry and Molecular Biology. 77: 223-7. PMID 11457660 DOI: 10.1016/S0960-0760(01)00057-7  0.84
2001 Faucher F, Lacoste L, Dufort I, Luu-The V. High metabolization of catecholestrogens by type 1 estrogen sulfotransferase (hEST1). The Journal of Steroid Biochemistry and Molecular Biology. 77: 83-6. PMID 11358677 DOI: 10.1016/S0960-0760(01)00025-5  0.8
2001 Zhu DW, Cantin L, Nahoum V, Rehse P, Luu-The V, Labrie F, Breton R, Lin SX. Crystallization and preliminary X-ray crystallographic analysis of the human type 3 3 alpha-hydroxysteroid dehydrogenase at 1.8 A resolution. Acta Crystallographica. Section D, Biological Crystallography. 57: 589-91. PMID 11264591 DOI: 10.1107/S0907444901001160  0.6
2001 Luu-The V, Dufort I, Pelletier G, Labrie F. Type 5 17beta-hydroxysteroid dehydrogenase: its role in the formation of androgens in women. Molecular and Cellular Endocrinology. 171: 77-82. PMID 11165014 DOI: 10.1016/S0303-7207(00)00425-1  0.8
2001 Dufort I, Labrie F, Luu-The V. Human types 1 and 3 3 alpha-hydroxysteroid dehydrogenases: differential lability and tissue distribution. The Journal of Clinical Endocrinology and Metabolism. 86: 841-6. PMID 11158055 DOI: 10.1210/Jcem.86.2.7216  0.8
2000 Provost PR, Blomquist CH, Godin C, Huang XF, Flamand N, Luu-The V, Nadeau D, Tremblay Y. Androgen Formation and Metabolism in the Pulmonary Epithelial Cell Line A549: Expression of 17β-Hydroxysteroid Dehydrogenase Type 5 and 3α-Hydroxysteroid Dehydrogenase Type 3. Endocrinology. 141: 2786-2794. PMID 28200972 DOI: 10.1210/Endo.141.8.7589  0.72
2000 Do-Rego JL, Mensah-Nyagan GA, Beaujean D, Vaudry D, Sieghart W, Luu-The V, Pelletier G, Vaudry H. gamma-Aminobutyric acid, acting through gamma -aminobutyric acid type A receptors, inhibits the biosynthesis of neurosteroids in the frog hypothalamus. Proceedings of the National Academy of Sciences of the United States of America. 97: 13925-30. PMID 11087816 DOI: 10.1073/Pnas.240269897  0.84
2000 Ngatcha BT, Luu-The V, Poirier D. Androsterone 3β-substituted derivatives as inhibitors of type 3 17β-hydroxysteroid dehydrogenase Bioorganic and Medicinal Chemistry Letters. 10: 2533-2536. PMID 11086723 DOI: 10.1016/S0960-894X(00)00517-5  0.84
2000 Zhang Y, Dufort I, Rheault P, Luu-The V. Characterization of a human 20alpha-hydroxysteroid dehydrogenase. Journal of Molecular Endocrinology. 25: 221-8. PMID 11013348 DOI: 10.1677/Jme.0.0250221  0.8
2000 Soucy P, Luu-The V. Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone. European Journal of Biochemistry / Febs. 267: 3243-7. PMID 10824109 DOI: 10.1046/J.1432-1327.2000.01349.X  0.84
2000 Zouboulis CC, Labrie F, Luu-The V, Labrie C, Pelletier G, El-Alfy M, Orfanos CE, Adler YD, Thornton MJ, Taylor AH, Mulligan K, Al-Azzawi F, Michalik L, Desvergne B, Basu-Modak S, et al. Subject Index Vol. 54, 2000 Hormone Research in Paediatrics. 54: 348-349. DOI: 10.1159/000053287  0.6
1999 El-Alfy M, Luu-The V, Huang XF, Berger L, Labrie F, Pelletier G. Localization of Type 5 17β-Hydroxysteroid Dehydrogenase, 3β-Hydroxysteroid Dehydrogenase, and Androgen Receptor in the Human Prostate by in Situ Hybridization and Immunocytochemistry. Endocrinology. 140: 1481-1491. PMID 28204308 DOI: 10.1210/endo.140.3.6585  0.72
1999 Dufort I, Rheault P, Huang XF, Soucy P, Luu-The V. Characteristics of a Highly Labile Human Type 5 17β-Hydroxysteroid Dehydrogenase1. Endocrinology. 140: 568-574. PMID 28200754 DOI: 10.1210/endo.140.2.6531  0.84
1999 Pelletier G, Luu-The V, Charbonneau A, Labrie F. Cellular localization of estrogen receptor beta messenger ribonucleic acid in cynomolgus monkey reproductive organs Biology of Reproduction. 61: 1249-1255. PMID 10529271 DOI: 10.1095/Biolreprod61.5.1249  0.84
1999 Rheault P, Charbonneau A, Luu-The V. Structure and activity of the murine type 5 17β-hydroxysteroid dehydrogenase gene Biochimica Et Biophysica Acta - Gene Structure and Expression. 1447: 17-24. PMID 10500239 DOI: 10.1016/S0167-4781(99)00106-2  0.84
1999 Labrie F, Labrie C, Bélanger A, Simard J, Gauthier S, Luu-The V, Mérand Y, Giguere V, Candas B, Luo S, Martel C, Singh SM, Fournier M, Coquet A, Richard V, et al. EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium. The Journal of Steroid Biochemistry and Molecular Biology. 69: 51-84. PMID 10418981 DOI: 10.1016/S0960-0760(99)00065-5  0.6
1999 Rheault P, Dufort I, Soucy P, Luu-The V. Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: identification of a new syntenic relationship. Cytogenetics and Cell Genetics. 84: 241-2. PMID 10393440 DOI: 10.1159/000015267  0.84
1999 Ciobanu LC, Boivin RP, Luu-The V, Labrie F, Poirier D. Potent inhibition of steroid sulfatase activity by 3-O-sulfamate 17alpha-benzyl(or 4'-tert-butylbenzyl)estra-1,3,5(10)-trienes: combination of two substituents at positions C3 and c17alpha of estradiol. Journal of Medicinal Chemistry. 42: 2280-6. PMID 10377235 DOI: 10.1021/Jm980677L  0.6
1999 Charbonneau A, Luu-The V. Assignment of steroid 5β-reductase (SRD5B1) and its pseudogene (SRD5BP1) to human chromosome bands 7q32→q33 and 1q23→q25, respectively, by in situ hybridization Cytogenetics and Cell Genetics. 84: 105-106. PMID 10343119 DOI: 10.1159/000015230  0.84
1999 El-Alfy M, Luu-The V, Huang XF, Berger L, Labrie F, Pelletier G. Localization of type 5 17beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase, and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry. Endocrinology. 140: 1481-91. PMID 10067877 DOI: 10.1210/Endo.140.3.6585  0.72
1999 Dufort I, Rheault P, Huang XF, Soucy P, Luu-The V. Characteristics of a highly labile human type 5 17beta-hydroxysteroid dehydrogenase. Endocrinology. 140: 568-74. PMID 9927279 DOI: 10.1210/Endo.140.2.6531  0.84
1998 Labrie F, Bélanger A, Luu-The V, Labrie C, Simard J, Cusan L, Gomez JL, Candas B. DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: its role during aging. Steroids. 63: 322-8. PMID 9618795 DOI: 10.1016/S0039-128X(98)00007-5  0.6
1997 Labrie F, Luu-The V, Lin SX, Labrie C, Simard J, Breton R, Bélanger A. The key role of 17 beta-hydroxysteroid dehydrogenases in sex steroid biology. Steroids. 62: 148-58. PMID 9029730 DOI: 10.1016/S0039-128X(96)00174-2  0.6
1996 Luu-The V, Bernier F, Dufort I. Steroid sulfotransferases. The Journal of Endocrinology. 150: S87-97. PMID 8943792  0.8
1996 Bernier F, Soucy P, Luu-The V. Human phenol sulfotransferase gene contains two alternative promoters: Structure and expression of the gene. Dna and Cell Biology. 15: 367-75. PMID 8924211 DOI: 10.1089/Dna.1996.15.367  0.84
1996 Dufort I, Soucy P, Labrie F, Luu-The V. Molecular cloning of human type 3 3 alpha-hydroxysteroid dehydrogenase that differs from 20 alpha-hydroxysteroid dehydrogenase by seven amino acids. Biochemical and Biophysical Research Communications. 228: 474-9. PMID 8920937 DOI: 10.1006/Bbrc.1996.1684  0.84
1996 Li X, Singh SM, Luu-The V, Côté J, Laplante S, Labrie F. Vinyl fluoride as a mimic of the "intermediate' enol form in the 5 alpha-reductase transformation: synthesis and in vitro activity of (N-1',1'-dimethylethyl)-3-haloandrost-3,5-diene-17 beta-carboxamides. Bioorganic & Medicinal Chemistry. 4: 55-60. PMID 8689240 DOI: 10.1016/0968-0896(95)00160-3  0.6
1996 Dufort I, Tremblay Y, Bélanger A, Labrie F, Luu-The V. Isolation and characterization of a stereospecific 3beta-hydroxysteriod sulfotransferase (pregnenolone sulfotransferase) cDNA. Dna and Cell Biology. 15: 481-7. PMID 8672244 DOI: 10.1089/Dna.1996.15.481  0.8
1996 Luu-The V, Bernier F, Dufort I, Labrie F. Molecular biology of steroid sulfotransferases. Annals of the New York Academy of Sciences. 784: 137-48. PMID 8651565 DOI: 10.1111/J.1749-6632.1996.Tb16233.X  0.8
1996 Lopez-Solache I, Luu-The V, Sŕalini G, Labrie F. Heterogeneity of rat type I 5α-reductase cDNA: cloning, expression and regulation by pituitary implants and dihydrotestosterone Biochimica Et Biophysica Acta. 1305: 139-144. PMID 8597599 DOI: 10.1016/0167-4781(95)00198-0  0.6
1996 Simard J, Durocher F, Mébarki F, Turgeon C, Sanchez R, Labrie Y, Couet J, Trudel C, Rhéaume E, Morel Y, Luu-The V, Labrie F. Molecular biology and genetics of the 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase gene family Journal of Endocrinology. 150. DOI: 10.1677/Joe.0.150S189  0.6
1995 Guérin SL, Leclerc S, Verreault H, Labrie F, Luu-The V. Overlapping cis-acting elements located in the first intron of the gene for type I 3 beta-hydroxysteroid dehydrogenase modulate its transcriptional activity. Molecular Endocrinology (Baltimore, Md.). 9: 1583-97. PMID 8584035 DOI: 10.1210/Mend.9.11.8584035  0.6
1995 Durocher F, Morissette J, Dufort I, Simard J, Luu-The V. Genetic linkage mapping of the dehydroepiandrosterone sulfotransferase (STD) gene on the chromosome 19q13.3 region. Genomics. 29: 781-3. PMID 8575776 DOI: 10.1006/Geno.1995.9935  0.84
1995 Simard J, Sanchez R, Durocher F, Rhéaume E, Turgeon C, Labrie Y, Luu-The V, Mebarki F, Morel Y, de Launoit Y. Structure-function relationships and molecular genetics of the 3 beta-hydroxysteroid dehydrogenase gene family. The Journal of Steroid Biochemistry and Molecular Biology. 55: 489-505. PMID 8547174 DOI: 10.1016/0960-0760(95)00198-0  0.32
1995 Séralini G, Luu-Thé V, Labrie F. Cloning and expression of human tyrosine aminotransferase cDNA. Biochimica Et Biophysica Acta. 1260: 97-101. PMID 7999802 DOI: 10.1016/0167-4781(94)00191-5  0.6
1995 Morissette J, Rhéaume E, Leblanc JF, Luu-The V, Labrie F, Simard J. Genetic linkage mapping of HSD3B1 and HSD3B2 encoding human types I and II 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase close to D1S514 and the centromeric D1Z5 locus. Cytogenetics and Cell Genetics. 69: 59-62. PMID 7835088 DOI: 10.1159/000133938  0.84
1995 Luu-The V, Dufort I, Paquet N, Reimnitz G, Labrie F. Structural characterization and expression of the human dehydroepiandrosterone sulfotransferase gene. Dna and Cell Biology. 14: 511-8. PMID 7598806 DOI: 10.1089/Dna.1995.14.511  0.8
1994 Verreault H, Dufort I, Simard J, Labrie F, Luu-The V. Dinucleotide repeat polymorphisms in the HSD3B2 gene. Human Molecular Genetics. 3: 384. PMID 8004119 DOI: 10.1093/Hmg/3.2.384  0.8
1993 Juneau C, Dupont E, Luu-The V, Labrie F, Pelletier G. Ontogenesis of 3β-hydroxysteroid dehydrogenase Δ5-Δ4 isomerase in the rat ovary as studied by immunocytochemistry and in situ hybridization Biology of Reproduction. 48: 226-234. PMID 8439611 DOI: 10.1095/Biolreprod48.2.226  0.84
1993 Simard J, Rhéaume E, Sanchez R, Laflamme N, de Launoit Y, Luu-The V, van Seters AP, Gordon RD, Bettendorf M, Heinrich U. Molecular basis of congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency. Molecular Endocrinology (Baltimore, Md.). 7: 716-28. PMID 8316254 DOI: 10.1210/Mend.7.5.8316254  0.32
1993 Riley SC, Bassett NS, Berdusco ETM, Yang K, Leystra-Lantz C, Luu-Thé V, Labrie F, Challis JRG, Halim A, Kanayama N, Maehara K, Takahashi M, Terao T, Schröcksnadel H, Daxenbichler G, et al. Contents, Vol. 35, 1993 Gynecologic and Obstetric Investigation. 35. DOI: 10.1159/000292713  0.6
1992 Riley SC, Dupont E, Walton JC, Luu-The V, Labrie F, Pelletier G, Challis JRG. Immunohistochemical localization of 3β-hydroxy-5-ene-steroid dehydrogenase/Δ5→Δ4 isomerase in human placenta and fetal membranes throughout gestation Journal of Clinical Endocrinology and Metabolism. 75: 956-961. PMID 1381375 DOI: 10.1210/Jcem.75.3.1381375  0.84
1992 Martel C, Rhéaume E, Takahashi M, Trudel C, Couët J, Luu-The V, Simard J, Labrie F. Distribution of 17β-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues The Journal of Steroid Biochemistry and Molecular Biology. 41: 597-603. PMID 1314080 DOI: 10.1016/0960-0760(92)90390-5  0.6
1991 Lachance Y, Luu-The V, Verreault H, Dumont M, Rhéaume E, Leblanc G, Labrie F. Structure of the human type II 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) gene: adrenal and gonadal specificity. Dna and Cell Biology. 10: 701-11. PMID 1741954 DOI: 10.1089/Dna.1991.10.701  0.6
1990 Martel C, Labrie C, Couët J, Dupont E, Trudel C, Luu-The V, Takahashi M, Pelletier G, Labrie F. Effects of human chorionic gonadotropin (hCG) and prolactin (PRL) on 3β-hydroxy-5-ene-steroid dehydrogenase/Δ5-Δ4 isomerase (3β-HSD) expression and activity in the rat ovary Molecular and Cellular Endocrinology. 72. PMID 2149342 DOI: 10.1016/0303-7207(90)90107-J  0.6
1989 Labrie F, Luu-The V, Labrie C, Bérubé D, Couet J, Zhao HF, Gagné R, Simard J. Characterization of two mRNA species encoding human estradiol 17 beta-dehydrogenase and assignment of the gene to chromosome 17. Journal of Steroid Biochemistry. 34: 189-97. PMID 2483219 DOI: 10.1016/0022-4731(89)90082-4  0.6
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