Vincent Giguere - Publications

McGill University, Montreal, QC, Canada 
Molecular Biology

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Deblois G, Smith HW, Tam IS, Gravel SP, Caron M, Savage P, Labbé DP, Bégin LR, Tremblay ML, Park M, Bourque G, St-Pierre J, Muller WJ, Giguère V. ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nature Communications. 7: 12156. PMID 27402251 DOI: 10.1038/Ncomms12156  0.52
2016 Yan M, Audet-Walsh É, Manteghi S, Rosa Dufour C, Walker B, Baba M, St-Pierre J, Giguère V, Pause A. Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα. Genes & Development. 30: 1034-46. PMID 27151976 DOI: 10.1101/Gad.281410.116  0.52
2016 Audet-Walsh É, Papadopoli DJ, Gravel SP, Yee T, Bridon G, Caron M, Bourque G, Giguère V, St-Pierre J. The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer. Cell Reports. PMID 26804918 DOI: 10.1016/J.Celrep.2015.12.086  0.52
2015 Yuk JM, Kim TS, Kim SY, Lee HM, Han J, Dufour CR, Kim JK, Jin HS, Yang CS, Park KS, Lee CH, Kim JM, Kweon GR, Choi HS, Vanacker JM, et al. Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation. Immunity. 43: 80-91. PMID 26200012 DOI: 10.1016/J.Immuni.2015.07.003  0.52
2015 Wang T, McDonald C, Petrenko NB, Leblanc M, Wang T, Giguere V, Evans RM, Patel VV, Pei L. Estrogen-related receptor α (ERRα) and ERRγ are essential coordinators of cardiac metabolism and function. Molecular and Cellular Biology. 35: 1281-98. PMID 25624346 DOI: 10.1128/Mcb.01156-14  0.52
2014 Perry MC, Dufour CR, Tam IS, B'chir W, Giguère V. Estrogen-related receptor-α coordinates transcriptional programs essential for exercise tolerance and muscle fitness. Molecular Endocrinology (Baltimore, Md.). 28: 2060-71. PMID 25361393 DOI: 10.1210/Me.2014-1281  0.52
2014 Perry MC, Dufour CR, Eichner LJ, Tsang DW, Deblois G, Muller WJ, Giguère V. ERBB2 deficiency alters an E2F-1-dependent adaptive stress response and leads to cardiac dysfunction. Molecular and Cellular Biology. 34: 4232-43. PMID 25246633 DOI: 10.1128/Mcb.00895-14  0.52
2014 Labbé DP, Nowak DG, Deblois G, Lessard L, Giguère V, Trotman LC, Tremblay ML. Prostate cancer genetic-susceptibility locus on chromosome 20q13 is amplified and coupled to androgen receptor-regulation in metastatic tumors. Molecular Cancer Research : McR. 12: 184-9. PMID 24379448 DOI: 10.1158/1541-7786.Mcr-13-0477  0.52
2013 Hong EJ, Levasseur MP, Dufour CR, Perry MC, Giguère V. Loss of estrogen-related receptor α promotes hepatocarcinogenesis development via metabolic and inflammatory disturbances. Proceedings of the National Academy of Sciences of the United States of America. 110: 17975-80. PMID 24127579 DOI: 10.1073/Pnas.1315319110  0.52
2013 Schade B, Lesurf R, Sanguin-Gendreau V, Bui T, Deblois G, O'Toole SA, Millar EK, Zardawi SJ, Lopez-Knowles E, Sutherland RL, Giguère V, Kahn M, Hallett M, Muller WJ. β-Catenin signaling is a critical event in ErbB2-mediated mammary tumor progression. Cancer Research. 73: 4474-87. PMID 23720052 DOI: 10.1158/0008-5472.Can-12-3925  0.52
2013 Chaveroux C, Eichner LJ, Dufour CR, Shatnawi A, Khoutorsky A, Bourque G, Sonenberg N, Giguère V. Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver. Cell Metabolism. 17: 586-98. PMID 23562079 DOI: 10.1016/J.Cmet.2013.03.003  0.52
2013 Deblois G, St-Pierre J, Giguère V. The PGC-1/ERR signaling axis in cancer Oncogene. 32: 3483-3490. PMID 23208510 DOI: 10.1038/Onc.2012.529  0.52
2012 Lessard L, Labbé DP, Deblois G, Bégin LR, Hardy S, Mes-Masson AM, Saad F, Trotman LC, Giguère V, Tremblay ML. PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer. Cancer Research. 72: 1529-37. PMID 22282656 DOI: 10.1158/0008-5472.Can-11-2602  0.52
2011 Michalek RD, Gerriets VA, Nichols AG, Inoue M, Kazmin D, Chang CY, Dwyer MA, Nelson ER, Pollizzi KN, Ilkayeva O, Giguere V, Zuercher WJ, Powell JD, Shinohara ML, McDonnell DP, et al. Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 108: 18348-53. PMID 22042850 DOI: 10.1073/Pnas.1108856108  0.52
2011 Dufour CR, Levasseur MP, Pham NH, Eichner LJ, Wilson BJ, Charest-Marcotte A, Duguay D, Poirier-Héon JF, Cermakian N, Giguère V. Genomic convergence among ERRα, PROX1, and BMAL1 in the control of metabolic clock outputs. Plos Genetics. 7: e1002143. PMID 21731503 DOI: 10.1371/Journal.Pgen.1002143  0.52
2011 Marquis JF, Kapoustina O, Langlais D, Ruddy R, Dufour CR, Kim BH, MacMicking JD, Giguère V, Gros P. Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis. Plos Genetics. 7: e1002097. PMID 21731497 DOI: 10.1371/Journal.Pgen.1002097  0.52
2011 Liu X, Nugoli M, Laferrière J, Saleh SM, Rodrigue-Gervais IG, Saleh M, Park M, Hallett MT, Muller WJ, Giguère V. Stromal retinoic acid receptor beta promotes mammary gland tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 774-9. PMID 21187396 DOI: 10.1073/Pnas.1011845108  0.52
2010 Eichner LJ, Perry MC, Dufour CR, Bertos N, Park M, St-Pierre J, Giguère V. miR-378(∗) mediates metabolic shift in breast cancer cells via the PGC-1β/ERRγ transcriptional pathway. Cell Metabolism. 12: 352-61. PMID 20889127 DOI: 10.1016/J.Cmet.2010.09.002  0.52
2010 Wilson BJ, Tremblay AM, Deblois G, Sylvain-Drolet G, Giguère V. An acetylation switch modulates the transcriptional activity of estrogen-related receptor alpha. Molecular Endocrinology (Baltimore, Md.). 24: 1349-58. PMID 20484414 DOI: 10.1210/Me.2009-0441  0.52
2010 Charest-Marcotte A, Dufour CR, Wilson BJ, Tremblay AM, Eichner LJ, Arlow DH, Mootha VK, Giguère V. The homeobox protein Prox1 is a negative modulator of ERR{alpha}/PGC-1{alpha} bioenergetic functions. Genes & Development. 24: 537-42. PMID 20194433 DOI: 10.1101/Gad.1871610  0.52
2010 Tremblay AM, Dufour CR, Ghahremani M, Reudelhuber TL, Giguère V. Physiological genomics identifies estrogen-related receptor alpha as a regulator of renal sodium and potassium homeostasis and the renin-angiotensin pathway. Molecular Endocrinology (Baltimore, Md.). 24: 22-32. PMID 19901197 DOI: 10.1210/Me.2009-0254  0.52
2009 Deblois G, Hall JA, Perry MC, Laganière J, Ghahremani M, Park M, Hallett M, Giguère V. Genome-wide identification of direct target genes implicates estrogen-related receptor alpha as a determinant of breast cancer heterogeneity. Cancer Research. 69: 6149-57. PMID 19622763 DOI: 10.1158/0008-5472.Can-09-1251  0.52
2009 Dydensborg AB, Rose AA, Wilson BJ, Grote D, Paquet M, Giguère V, Siegel PM, Bouchard M. GATA3 inhibits breast cancer growth and pulmonary breast cancer metastasis. Oncogene. 28: 2634-42. PMID 19483726 DOI: 10.1038/Onc.2009.126  0.52
2008 Wilson BJ, Giguère V. Meta-analysis of human cancer microarrays reveals GATA3 is integral to the estrogen receptor alpha pathway. Molecular Cancer. 7: 49. PMID 18533032 DOI: 10.1186/1476-4598-7-49  0.52
2008 Tremblay AM, Wilson BJ, Yang XJ, Giguère V. Phosphorylation-dependent sumoylation regulates estrogen-related receptor-alpha and -gamma transcriptional activity through a synergy control motif. Molecular Endocrinology (Baltimore, Md.). 22: 570-84. PMID 18063693 DOI: 10.1210/Me.2007-0357  0.52
2007 Tremblay AM, Giguère V. The NR3B subgroup: an ovERRview. Nuclear Receptor Signaling. 5: e009. PMID 18174917 DOI: 10.1621/Nrs.05009  0.52
2007 Wilson BJ, Giguère V. Identification of novel pathway partners of p68 and p72 RNA helicases through Oncomine meta-analysis. Bmc Genomics. 8: 419. PMID 18005418 DOI: 10.1186/1471-2164-8-419  0.52
2007 Sonoda J, Laganière J, Mehl IR, Barish GD, Chong LW, Li X, Scheffler IE, Mock DC, Bataille AR, Robert F, Lee CH, Giguère V, Evans RM. Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense. Genes & Development. 21: 1909-20. PMID 17671090 DOI: 10.1101/Gad.1553007  0.52
2007 Huss JM, Imahashi K, Dufour CR, Weinheimer CJ, Courtois M, Kovacs A, Giguère V, Murphy E, Kelly DP. The nuclear receptor ERRalpha is required for the bioenergetic and functional adaptation to cardiac pressure overload. Cell Metabolism. 6: 25-37. PMID 17618854 DOI: 10.1016/J.Cmet.2007.06.005  0.52
2007 Alaynick WA, Kondo RP, Xie W, He W, Dufour CR, Downes M, Jonker JW, Giles W, Naviaux RK, Giguère V, Evans RM. ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart. Cell Metabolism. 6: 13-24. PMID 17618853 DOI: 10.1016/J.Cmet.2007.06.007  0.52
2007 Dufour CR, Wilson BJ, Huss JM, Kelly DP, Alaynick WA, Downes M, Evans RM, Blanchette M, Giguère V. Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma. Cell Metabolism. 5: 345-56. PMID 17488637 DOI: 10.1016/J.Cmet.2007.03.007  0.52
2006 Benoit G, Cooney A, Giguere V, Ingraham H, Lazar M, Muscat G, Perlmann T, Renaud JP, Schwabe J, Sladek F, Tsai MJ, Laudet V. International union of pharmacology. LXVI. Orphan nuclear receptors Pharmacological Reviews. 58: 798-836. PMID 17132856 DOI: 10.1124/Pr.58.4.10  0.52
2006 Lu NZ, Wardell SE, Burnstein KL, Defranco D, Fuller PJ, Giguere V, Hochberg RB, McKay L, Renoir JM, Weigel NL, Wilson EM, McDonnell DP, Cidlowski JA. International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors. Pharmacological Reviews. 58: 782-97. PMID 17132855 DOI: 10.1124/Pr.58.4.9  0.52
2006 Blanchette M, Bataille AR, Chen X, Poitras C, Laganière J, Lefèbvre C, Deblois G, Giguère V, Ferretti V, Bergeron D, Coulombe B, Robert F. Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression. Genome Research. 16: 656-68. PMID 16606704 DOI: 10.1101/Gr.4866006  0.52
2006 Grégoire S, Tremblay AM, Xiao L, Yang Q, Ma K, Nie J, Mao Z, Wu Z, Giguère V, Yang XJ. Control of MEF2 transcriptional activity by coordinated phosphorylation and sumoylation. The Journal of Biological Chemistry. 281: 4423-33. PMID 16356933 DOI: 10.1074/Jbc.M509471200  0.52
2006 Herzog B, Cardenas J, Hall RK, Villena JA, Budge PJ, Giguère V, Granner DK, Kralli A. Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription. The Journal of Biological Chemistry. 281: 99-106. PMID 16267049 DOI: 10.1074/Jbc.M509276200  0.52
2005 Wende AR, Huss JM, Schaeffer PJ, Giguère V, Kelly DP. PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolism. Molecular and Cellular Biology. 25: 10684-94. PMID 16314495 DOI: 10.1128/Mcb.25.24.10684-10694.2005  0.52
2005 Laflamme N, Giroux S, Loredo-Osti JC, Elfassihi L, Dodin S, Blanchet C, Morgan K, Giguère V, Rousseau F. A frequent regulatory variant of the estrogen-related receptor alpha gene associated with BMD in French-Canadian premenopausal women. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 938-44. PMID 15883633 DOI: 10.1359/Jbmr.050203  0.52
2005 Snyder JM, Jenkins-Moore M, Jackson SK, Goss KL, Dai HH, Bangsund PJ, Giguere V, McGowan SE. Alveolarization in retinoic acid receptor-beta-deficient mice. Pediatric Research. 57: 384-91. PMID 15635054 DOI: 10.1203/01.Pdr.0000151315.81106.D3  0.52
2004 Huss JM, Torra IP, Staels B, Giguère V, Kelly DP. Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle. Molecular and Cellular Biology. 24: 9079-91. PMID 15456881 DOI: 10.1128/Mcb.24.20.9079-9091.2004  0.52
2004 Laganière J, Tremblay GB, Dufour CR, Giroux S, Rousseau F, Giguère V. A polymorphic autoregulatory hormone response element in the human estrogen-related receptor alpha (ERRalpha) promoter dictates peroxisome proliferator-activated receptor gamma coactivator-1alpha control of ERRalpha expression. The Journal of Biological Chemistry. 279: 18504-10. PMID 14978033 DOI: 10.1074/Jbc.M313543200  0.52
2003 Moraitis AN, Giguère V. The co-repressor hairless protects RORalpha orphan nuclear receptor from proteasome-mediated degradation. The Journal of Biological Chemistry. 278: 52511-8. PMID 14570920 DOI: 10.1074/Jbc.M308152200  1
2002 Tremblay GB, Giguère V. Coregulators of estrogen receptor action. Critical Reviews in Eukaryotic Gene Expression. 12: 1-22. PMID 12433063 DOI: 10.1615/Critreveukaryotgeneexpr.V12.I1.10  0.52
2002 Moraitis AN, Giguère V, Thompson CC. Novel mechanism of nuclear receptor corepressor interaction dictated by activation function 2 helix determinants. Molecular and Cellular Biology. 22: 6831-41. PMID 12215540 DOI: 10.1128/Mcb.22.19.6831-6841.2002  0.52
2001 Tremblay A, Giguère V. Contribution of steroid receptor coactivator-1 and CREB binding protein in ligand-independent activity of estrogen receptor β Journal of Steroid Biochemistry and Molecular Biology. 77: 19-27. PMID 11358671 DOI: 10.1016/S0960-0760(01)00031-0  0.52
2001 Sauvé F, McBroom LD, Gallant J, Moraitis AN, Labrie F, Giguère V. CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant. Molecular and Cellular Biology. 21: 343-53. PMID 11113208 DOI: 10.1128/Mcb.21.1.343-353.2001  1
1999 Folberg A, Nagy Kovács E, Luo J, Giguère V, Featherstone MS. RARβ mediates the response of Hoxd4 and Hoxb4 to exogenous retinoic acid Developmental Dynamics. 215: 96-107. PMID 10373014 DOI: 10.1002/(Sici)1097-0177(199906)215:2<96::Aid-Dvdy2>3.0.Co;2-T  0.52
1999 Tremblay A, Tremblay GB, Labrie F, Giguère V. Ligand-Independent recruitment of SRC-1 to estrogen receptor β through phosphorylation of activation function AF-1 Molecular Cell. 3: 513-519. PMID 10230404 DOI: 10.1016/S1097-2765(00)80479-7  0.52
1999 Auwerx J, Baulieu E, Beato M, Becker-Andre M, Burbach PH, Camerino G, Chambon P, Cooney A, Dejean A, Dreyer C, Evans RM, Gannon F, Giguere V, Gronemeyer H, Gustafsson JA, et al. A unified nomenclature system for the nuclear receptor superfamily Cell. 97: 161-163. PMID 10219237 DOI: 10.1016/S0092-8674(00)80726-6  0.52
1999 Moraitis AN, Giguère V. Transition from monomeric to homodimeric DNA binding by nuclear receptors: identification of RevErbAalpha determinants required for RORalpha homodimer complex formation. Molecular Endocrinology (Baltimore, Md.). 13: 431-9. PMID 10077000 DOI: 10.1210/Mend.13.3.0250  1
1999 Tremblay GB, Tremblay A, Labrie F, Giguère V. Dominant activity of activation function 1 (AF-1) and differential stoichiometric requirements for AF-1 and -2 in the estrogen receptor α-β heterodimeric complex Molecular and Cellular Biology. 19: 1919-1927. PMID 10022879 DOI: 10.1128/Mcb.19.3.1919  0.52
1998 Chiang MY, Misner D, Kempermann G, Schikorski T, Giguère V, Sucov HM, Gage FH, Stevens CF, Evans RM. An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression. Neuron. 21: 1353-61. PMID 9883728 DOI: 10.1016/S0896-6273(00)80654-6  0.52
1998 Giguère V, Tremblay A, Tremblay GB. Estrogen receptor β: Re-evaluation of estrogen and antiestrogen signaling Steroids. 63: 335-339. PMID 9618797 DOI: 10.1016/S0039-128X(98)00024-5  0.52
1997 Lee RY, Luo J, Evans RM, Giguere V, Sucov HM. Compartment-selective sensitivity of cardiovascular morphogenesis to combinations of retinoic acid receptor gene mutations Circulation Research. 80: 757-764. PMID 9168777 DOI: 10.1161/01.Res.80.6.757  0.52
1996 Luo J, Sucov HM, Bader JA, Evans RM, Giguère V. Compound mutants for retinoic acid receptor (RAR) β and RARα1 reveal developmental functions for multiple RARβ isoforms Mechanisms of Development. 55: 33-44. PMID 8734497 DOI: 10.1016/0925-4773(95)00488-2  0.52
1996 Giguère V, Fawcett D, Luo J, Evans RM, Sucov HM. Genetic analysis of the retinoid signal Annals of the New York Academy of Sciences. 785: 12-22. PMID 8702117 DOI: 10.1111/J.1749-6632.1996.Tb56238.X  0.52
1995 Luo J, Pasceri P, Conlon RA, Rossant J, Giguère V. Mice lacking all isoforms of retinoic acid receptor beta develop normally and are susceptible to the teratogenic effects of retinoic acid. Mechanisms of Development. 53: 61-71. PMID 8555112 DOI: 10.1016/0925-4773(95)00424-6  0.52
1994 Predki PF, Zamble D, Sarkar B, Giguère V. Ordered binding of retinoic acid and retinoid-X receptors to asymmetric response elements involves determinants adjacent to the DNA-binding domain Molecular Endocrinology. 8: 31-39. PMID 8152429 DOI: 10.1210/Mend.8.1.8152429  0.52
1994 Norris AW, Cheng L, Giguère V, Rosenberger M, Li E. Measurement of subnanomolar retinoic acid binding affinities for cellular retinoic acid binding proteins by fluorometric titration Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 1209: 10-18. PMID 7947970 DOI: 10.1016/0167-4838(94)90130-9  0.52
1989 Giguere V, Ong ES, Evans RM, Tabin CJ. Spatial and temporal expression of the retinoic acid receptor in the regenerating amphibian limb Nature. 337: 566-569. PMID 2536901 DOI: 10.1038/337566A0  0.52
1986 Thomas DB, Giguere V, Graham CM, Oliveira OLP. Autoimmunity to Thy-1 European Journal of Immunology. 16: 40-47. PMID 2419137 DOI: 10.1002/Eji.1830160109  0.52
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