David Goltzman - Publications

Affiliations: 
McGill University, Montreal, QC, Canada 
Area:
Animal Physiology Biology, Molecular Biology

248 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chen H, Hu X, Yang R, Wu G, Tan Q, Goltzman D, Miao D. SIRT1/FOXO3a axis plays an important role in the prevention of mandibular bone loss induced by 1,25(OH)D deficiency. International Journal of Biological Sciences. 16: 2712-2726. PMID 33110391 DOI: 10.7150/Ijbs.48169  0.406
2020 Morin SN, Berger C, Liu W, Prior JC, Cheung AM, Hanley DA, Boyd SK, Wong AKO, Papaioannou A, Rahme E, Goltzman D. Differences in fracture prevalence and in bone mineral density between Chinese and White Canadians: the Canadian Multicentre Osteoporosis Study (CaMos). Archives of Osteoporosis. 15: 147. PMID 32955674 DOI: 10.1007/S11657-020-00822-4  0.362
2020 Lentle BC, Berger C, Brown JP, Probyn L, Langsetmo L, Hammond I, Hu J, Leslie WD, Prior JC, Hanley DA, Adachi JD, Josse RG, Cheung AM, Kaiser SM, Towheed T, ... ... Goltzman D, et al. Vertebral Fractures: Which Radiological Criteria Are Better Associated With the Clinical Course of Osteoporosis? Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes. 846537120943529. PMID 32755312 DOI: 10.1177/0846537120943529  0.302
2020 Qiao W, Yu S, Sun H, Chen L, Wang R, Wu X, Goltzman D, Miao D. 1,25-Dihydroxyvitamin D insufficiency accelerates age-related bone loss by increasing oxidative stress and cell senescence. American Journal of Translational Research. 12: 507-518. PMID 32194899  0.32
2020 Tanaka KI, Kanazawa I, Richards JB, Goltzman D, Sugimoto T. Modulators of Fam210a and Roles of Fam210a in the Function of Myoblasts. Calcified Tissue International. PMID 31980842 DOI: 10.1007/S00223-020-00661-Y  0.316
2020 Abi-Rafeh J, Troka I, Canaff L, Hendy G, Goltzman D. Abstract 36: Menin Functions Critically In Mesenchymal Stem Cells And Osteoblast Progenitors To Promote Bone Development And Maintenance In Vivo Plastic and Reconstructive Surgery. Global Open. 8: 23. DOI: 10.1097/01.Gox.0000667208.64323.49  0.344
2019 Yang R, Chen J, Zhang J, Qin R, Wang R, Qiu Y, Mao Z, Goltzman D, Miao D. 1,25-Dihydroxyvitamin D protects against age-related osteoporosis by a novel VDR-Ezh2-p16 signal axis. Aging Cell. e13095. PMID 31880094 DOI: 10.1111/Acel.13095  0.417
2019 Sun H, Qiao W, Cui M, Yang C, Wang R, Goltzman D, Jin J, Miao D. The Polycomb Protein Bmi1 Plays a Crucial Role in the Prevention of 1,25(OH) D Deficiency-induced Bone Loss. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31725940 DOI: 10.1002/Jbmr.3921  0.417
2019 Goltzman D. The Aging Skeleton. Advances in Experimental Medicine and Biology. 1164: 153-160. PMID 31576547 DOI: 10.1007/978-3-030-22254-3_12  0.395
2019 Bliuc D, Tran T, van Geel T, Adachi JD, Berger C, van den Bergh J, Eisman JA, Geusens P, Goltzman D, Hanley DA, Josse R, Kaiser S, Kovacs CS, Langsetmo L, Prior JC, et al. Reduced Bone Loss Is Associated With Reduced Mortality Risk in Subjects Exposed to Nitrogen Bisphosphonates: A Mediation Analysis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31402509 DOI: 10.1002/Jbmr.3816  0.362
2019 Nguyen-Yamamoto L, Tanaka KI, St-Arnaud R, Goltzman D. Vitamin D-regulated osteocytic sclerostin and BMP2 modulate uremic extraskeletal calcification. Jci Insight. 4. PMID 31292298 DOI: 10.1172/Jci.Insight.126467  0.346
2019 Adachi JD, Berger C, Barron R, Weycker D, Anastassiades TP, Davison KS, Hanley DA, Ioannidis G, Jackson SA, Josse RG, Kaiser SM, Kovacs CS, Leslie WD, Morin SN, Papaioannou A, ... ... Goltzman D, et al. Predictors of imminent non-vertebral fracture in elderly women with osteoporosis, low bone mass, or a history of fracture, based on data from the population-based Canadian Multicentre Osteoporosis Study (CaMos). Archives of Osteoporosis. 14: 53. PMID 31098708 DOI: 10.1007/S11657-019-0598-X  0.328
2019 Cooke-Hubley S, Gao Z, Mugford G, Kaiser SM, Goltzman D, Leslie WD, Davison KS, Brown JP, Probyn L, Lentle B, Prior JC, Kovacs CS. Parity and lactation are not associated with incident fragility fractures or radiographic vertebral fractures over 16 years of follow-up: Canadian Multicentre Osteoporosis Study (CaMos). Archives of Osteoporosis. 14: 49. PMID 31037359 DOI: 10.1007/S11657-019-0601-6  0.336
2019 Chen L, Yang R, Qiao W, Zhang W, Chen J, Mao L, Goltzman D, Miao D. 1,25-Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2-antioxidant signaling and inactivation of p16/p53-senescence signaling. Aging Cell. e12951. PMID 30907059 DOI: 10.1111/Acel.12951  0.343
2019 Borhan S, Papaioannou A, Gajic-Veljanoski O, Kennedy C, Ioannidis G, Berger C, Goltzman D, Josse R, Kovacs CS, Hanley DA, Prior JC, Morin SN, Kaiser SM, Cheung AM, Thabane L, et al. Incident Fragility Fractures Have a Long-Term Negative Impact on Health-Related Quality of Life of Older People: The Canadian Multicentre Osteoporosis Study. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. e3666. PMID 30723960 DOI: 10.1002/Jbmr.3666  0.303
2019 Lentle B, Koromani F, Brown J, Oei L, Ward L, Goltzman D, Rivadeneira F, Leslie WD, Probyn L, Prior J, Hammond I, Cheung A, Oei E. The Radiology of Osteoporotic Vertebral Fractures Revisited. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 30645770 DOI: 10.1002/Jbmr.3669  0.341
2019 Samelson EJ, Broe KE, Xu H, Yang L, Boyd S, Biver E, Szulc P, Adachi J, Amin S, Atkinson E, Berger C, Burt L, Chapurlat R, Chevalley T, Ferrari S, ... Goltzman D, et al. Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study. The Lancet. Diabetes & Endocrinology. 7: 34-43. PMID 30503163 DOI: 10.1016/S2213-8587(18)30308-5  0.382
2018 Morris JA, Kemp JP, Youlten SE, Laurent L, Logan JG, Chai RC, Vulpescu NA, Forgetta V, Kleinman A, Mohanty ST, Sergio CM, Quinn J, Nguyen-Yamamoto L, Luco AL, Vijay J, ... ... Goltzman D, et al. An atlas of genetic influences on osteoporosis in humans and mice. Nature Genetics. PMID 30598549 DOI: 10.1038/S41588-018-0302-X  0.395
2018 Zhu Q, Zhou X, Zhu M, Wang Q, Goltzman D, Karaplis A, Miao D. Endogenous Parathyroid Hormone-Related Protein Compensates for the Absence of Parathyroid Hormone in Promoting Bone Accrual In Vivo in a Model of Bone Marrow Ablation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 33: 2239-2241. PMID 30521118 DOI: 10.1002/Jbmr.3582  0.407
2018 Goltzman D. Physiology of Parathyroid Hormone. Endocrinology and Metabolism Clinics of North America. 47: 743-758. PMID 30390810 DOI: 10.1016/J.Ecl.2018.07.003  0.42
2018 Cheishvili D, Parashar S, Mahmood N, Arakelian A, Kremer R, Goltzman D, Szyf M, Rabbani SA. Identification of an Epigenetic Signature of Osteoporosis in Blood DNA of Post-menopausal Women. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29924424 DOI: 10.1002/Jbmr.3527  0.321
2018 Zhang Y, Chen G, Gu Z, Sun H, Karaplis A, Goltzman D, Miao D. DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide. International Journal of Biological Sciences. 14: 508-517. PMID 29805302 DOI: 10.7150/Ijbs.23318  0.407
2018 Lentle BC, Oei E, Goltzman D, Rivadeneira F, Hammond I, Oei L, Kovacs CS, Hanley DA, Prior JC, Leslie WD, Kaiser SM, Adachi JD, Probyn L, Brown J, Cheung AM, et al. Vertebral fractures and morphometric deformities. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29750843 DOI: 10.1002/Jbmr.3470  0.313
2018 Rizzoli R, Biver E, Bonjour J, Coxam V, Goltzman D, Kanis JA, Lappe J, Rejnmark L, Sahni S, Weaver C, Weiler H, Reginster J-. Benefits and safety of dietary protein for bone health-an expert consensus paper endorsed by the European Society for Clinical and Economical Aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation. Osteoporosis International. 29: 1933-1948. PMID 29740667 DOI: 10.1007/S00198-018-4534-5  0.385
2018 Gong A, Chen J, Wu J, Li J, Wang L, Goltzman D, Miao D. 1,25-Dihydroxyvitamin D deficiency accelerates alveolar bone loss independent of aging and extracellular calcium and phosphorus. Journal of Periodontology. PMID 29637561 DOI: 10.1002/Jper.17-0542  0.421
2018 Tanaka KI, Xue Y, Nguyen-Yamamoto L, Morris JA, Kanazawa I, Sugimoto T, Wing SS, Richards JB, Goltzman D. FAM210A is a novel determinant of bone and muscle structure and strength. Proceedings of the National Academy of Sciences of the United States of America. PMID 29618611 DOI: 10.1073/Pnas.1719089115  0.399
2018 Chen L, Yang R, Qiao W, Yuan X, Wang S, Goltzman D, Miao D. 1,25-Dihydroxy vitamin D prevents tumorigenesis by inhibiting oxidative stress and inducing tumor cellular senescence in mice. International Journal of Cancer. PMID 29441580 DOI: 10.1002/Ijc.31317  0.319
2017 Lentle BC, Berger C, Probyn L, Brown JP, Langsetmo L, Fine B, Lian K, Shergill AK, Trollip J, Jackson S, Leslie WD, Prior JC, Kaiser SM, Hanley DA, Adachi JD, ... ... Goltzman D, et al. Comparative Analysis of the Radiology of Osteoporotic Vertebral Fractures in Women and Men: Cross-Sectional and Longitudinal Observations from the Canadian Multicentre Osteoporosis Study (CaMos). Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28722766 DOI: 10.1002/Jbmr.3222  0.318
2017 Matsumoto Y, La Rose J, Lim M, Adissu HA, Law N, Mao X, Cong F, Mera P, Karsenty G, Goltzman D, Changoor A, Zhang L, Stajkowski M, Grynpas MD, Bergmann C, et al. Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism. The Journal of Clinical Investigation. PMID 28581440 DOI: 10.1172/Jci92233  0.384
2017 Torremadé N, Bozic M, Goltzman D, Fernandez E, Valdivielso JM. Effects of the Administration of 25(OH) Vitamin D3 in an Experimental Model of Chronic Kidney Disease in Animals Null for 1-Alpha-Hydroxylase. Plos One. 12: e0170654. PMID 28107527 DOI: 10.1371/Journal.Pone.0170654  0.345
2017 Nguyen-Yamamoto L, Karaplis AC, St-Arnaud R, Goltzman D. Fibroblast Growth Factor 23 Regulation by Systemic and Local Osteoblast-Synthesized 1,25-Dihydroxyvitamin D. Journal of the American Society of Nephrology : Jasn. 28: 586-597. PMID 27535551 DOI: 10.1681/Asn.2016010066  0.371
2017 Cooke-Hubley S, Zhiwei G, Mugford G, Kaiser SM, Goltzman D, Lesliek WD, Davison S, Prior JC, Kovacs CS. Parity and Lactation Are Not Associated with BMD Loss or Incident Major Fragility Fractures Over 15 Years: Canadian Multicentre Osteoporosis Study (CaMos) Canadian Journal of Diabetes. 41. DOI: 10.1016/J.Jcjd.2017.08.008  0.323
2016 Naylor KL, Prior J, Garg AX, Berger C, Langsetmo L, Adachi JD, Goltzman D, Kovacs CS, Josse RG, Leslie WD. Trabecular Bone Score and Incident Fragility Fracture Risk in Adults with Reduced Kidney Function. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 27797885 DOI: 10.2215/Cjn.00720116  0.385
2016 Camirand A, Goltzman D, Gupta A, Kaouass M, Panda D, Karaplis A. The Role of Parathyroid Hormone-Related Protein (PTHrP) in Osteoblast Response to Microgravity: Mechanistic Implications for Osteoporosis Development. Plos One. 11: e0160034. PMID 27463808 DOI: 10.1371/Journal.Pone.0160034  0.396
2016 Zhou X, Dai X, Wu X, Ji J, Karaplis A, Goltzman D, Yang X, Miao D. Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment. Scientific Reports. 6: 29171. PMID 27373231 DOI: 10.1038/Srep29171  0.361
2016 Torremadé N, Bozic M, Panizo S, Barrio-Vazquez S, Fernandez-Martín JL, Encinas M, Goltzman D, Arcidiacono MV, Fernandez E, Valdivielso JM. Vascular Calcification Induced by Chronic Kidney Disease Is Mediated by an Increase of 1α-Hydroxylase Expression in Vascular Smooth Muscle Cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 31: 1865-1876. PMID 27074284 DOI: 10.1002/Jbmr.2852  0.358
2016 Langsetmo L, Barr SI, Dasgupta K, Berger C, Kovacs CS, Josse RG, Adachi JD, Hanley DA, Prior JC, Brown JP, Morin SN, Davison KS, Goltzman D, Kreiger N. Dietary patterns in men and women are simultaneously determinants of altered glucose metabolism and bone metabolism. Nutrition Research (New York, N.Y.). 36: 328-36. PMID 27001278 DOI: 10.1016/J.Nutres.2015.12.010  0.356
2016 Sun W, Wu J, Huang L, Liu H, Wang R, Karaplis A, Goltzman D, Miao D. PTHrP nuclear localization and carboxyl terminus sequences modulate dental and mandibular development in part via the action of p27. Endocrinology. en20151555. PMID 26859332 DOI: 10.1210/En.2015-1555  0.313
2016 Bai X, Miao D, Xiao S, Qiu D, St-Arnaud R, Petkovich M, Gupta A, Goltzman D, Karaplis AC. CYP24 inhibition as a therapeutic target in FGF23-mediated renal phosphate wasting disorders. The Journal of Clinical Investigation. PMID 26784541 DOI: 10.1172/Jci81928  0.359
2016 Vaninetti N, Kirkland S, Thompson K, Theriault C, Prior J, Kovacs C, Adachi R, Towheed T, Leslie W, Davison KS, Morin S, Goltzman D, Kaiser S. Warfarin use and changes in bone mineral density in the population-based canadian multicentre osteoporosis study (CaMos) Bone Abstracts. DOI: 10.1530/Boneabs.5.P360  0.347
2016 Xu H, Ding D, Miao D, Goltzman D, Shi Q, Liang Q, Wang Y. A high-calcium, high-phosphorus, high-lactose diet rescues the intervertebral disc degeneration phenotype induced by the deficiency of 1,25(OH)2D3 Journal of Orthopaedic Translation. 7: 113. DOI: 10.1016/J.Jot.2016.06.130  0.302
2015 Langsetmo L, Barr SI, Berger C, Kreiger N, Rahme E, Adachi JD, Papaioannou A, Kaiser SM, Prior JC, Hanley DA, Kovacs CS, Josse RG, Goltzman D. Associations of Protein Intake and Protein Source with Bone Mineral Density and Fracture Risk: A Population-Based Cohort Study. The Journal of Nutrition, Health & Aging. 19: 861-8. PMID 26412291 DOI: 10.1007/S12603-015-0544-6  0.356
2015 Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A, Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C, Kleinman A, Styrkarsdottir U, Liu CT, Uggla C, Evans DS, ... ... Goltzman D, et al. Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Nature. PMID 26367794 DOI: 10.1038/Nature14878  0.329
2015 Xue Y, Ying L, Horst RL, Watson G, Goltzman D. Androgens Attenuate Vitamin D Production Induced by UVB Irradiation of the Skin of Male Mice by an Enzymatic Mechanism. The Journal of Investigative Dermatology. PMID 26214382 DOI: 10.1038/Jid.2015.297  0.327
2015 Hirai T, Kobayashi T, Nishimori S, Karaplis AC, Goltzman D, Kronenberg HM. Bone Is a Major Target of PTH/PTHrP Receptor Signaling in Regulation of Fetal Blood Calcium Homeostasis. Endocrinology. 156: 2774-80. PMID 26052897 DOI: 10.1210/En.2014-1835  0.395
2015 Zhu M, Zhang J, Dong Z, Zhang Y, Wang R, Karaplis A, Goltzman D, Miao D. The p27 Pathway Modulates the Regulation of Skeletal Growth and Osteoblastic Bone Formation by Parathyroid Hormone-Related Peptide. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 25917430 DOI: 10.1002/Jbmr.2544  0.391
2015 Palcu P, Dion N, Ste-Marie LG, Goltzman D, Radziunas I, Miller PD, Jamal SA. Teriparatide and bone turnover and formation in a hemodialysis patient with low-turnover bone disease: a case report. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 65: 933-6. PMID 25843705 DOI: 10.1053/J.Ajkd.2015.01.025  0.402
2015 Goltzman D, Hendy GN. The calcium-sensing receptor in bone--mechanistic and therapeutic insights. Nature Reviews. Endocrinology. 11: 298-307. PMID 25752283 DOI: 10.1038/Nrendo.2015.30  0.423
2015 Zhang W, Chen L, Zhang L, Xiao M, Ding J, Goltzman D, Miao D. Administration of exogenous 1,25(OH)2D3 normalizes overactivation of the central renin-angiotensin system in 1α(OH)ase knockout mice. Neuroscience Letters. 588: 184-9. PMID 25576706 DOI: 10.1016/J.Neulet.2015.01.013  0.322
2015 Sun W, Chen L, Zhang W, Wang R, Goltzman D, Miao D. Active vitamin D deficiency mediated by extracellular calcium and phosphorus results in male infertility in young mice. American Journal of Physiology. Endocrinology and Metabolism. 308: E51-62. PMID 25370849 DOI: 10.1152/Ajpendo.00076.2014  0.329
2015 Goltzman D. Inferences from genetically modified mouse models on the skeletal actions of vitamin D. The Journal of Steroid Biochemistry and Molecular Biology. 148: 219-224. PMID 25237033 DOI: 10.1016/J.Jsbmb.2014.09.011  0.411
2015 Berger C, Almohareb O, Langsetmo L, Hanley DA, Kovacs CS, Josse RG, Adachi JD, Prior JC, Towheed T, Davison KS, Kaiser SM, Brown JP, Goltzman D. Characteristics of hyperparathyroid states in the Canadian multicentre osteoporosis study (CaMos) and relationship to skeletal markers. Clinical Endocrinology. 82: 359-68. PMID 25059283 DOI: 10.1111/Cen.12569  0.336
2015 Goltzman D, Hendy GN, White JH. Vitamin D and its receptor during late development. Biochimica Et Biophysica Acta. 1849: 171-180. PMID 24939836 DOI: 10.1016/J.Bbagrm.2014.05.026  0.416
2014 Johansson H, Kanis JA, Odén A, Leslie WD, Fujiwara S, Glüer CC, Kroger H, LaCroix AZ, Lau E, Melton LJ, Eisman JA, O'Neill TW, Goltzman D, Reid DM, McCloskey E. Impact of femoral neck and lumbar spine BMD discordances on FRAX probabilities in women: a meta-analysis of international cohorts. Calcified Tissue International. 95: 428-35. PMID 25187239 DOI: 10.1007/S00223-014-9911-2  0.309
2014 Salem S, Gao C, Li A, Wang H, Nguyen-Yamamoto L, Goltzman D, Henderson JE, Gros P. A novel role for interferon regulatory factor 1 (IRF1) in regulation of bone metabolism. Journal of Cellular and Molecular Medicine. 18: 1588-98. PMID 24954358 DOI: 10.1111/Jcmm.12327  0.424
2014 Fraser LA, Adachi JD, Leslie WD, Goltzman D, Josse R, Prior J, Kaiser S, Kreiger N, Kovacs CS, Anastassiades TP, Papaioannou A. Effect of Anticholinergic Medications on Falls, Fracture Risk, and Bone Mineral Density Over a 10-Year Period. The Annals of Pharmacotherapy. 48: 954-961. PMID 24816210 DOI: 10.1177/1060028014535363  0.309
2014 Leslie WD, Langsetmo L, Zhou W, Goltzman D, Kovacs CS, Prior J, Josse R, Olszynski WP, Davison KS, Anastassiades T, Towheed T, Hanley DA, Kaiser SM, Lentle B, Kreiger N, et al. Choice of lumbar spine bone density reference database for fracture prediction in men and women: a population-based analysis. Journal of Clinical Densitometry : the Official Journal of the International Society For Clinical Densitometry. 17: 295-300. PMID 24613388 DOI: 10.1016/J.Jocd.2013.09.003  0.334
2014 Moura C, Bernatsky S, Abrahamowicz M, Papaioannou A, Bessette L, Adachi J, Goltzman D, Prior J, Kreiger N, Towheed T, Leslie WD, Kaiser S, Ioannidis G, Pickard L, Fraser LA, et al. Antidepressant use and 10-year incident fracture risk: The population-based Canadian Multicentre Osteoporosis Study (CaMoS) Osteoporosis International. 25: 1473-1481. PMID 24566587 DOI: 10.1007/S00198-014-2649-X  0.336
2014 Yip KH, Kolesnikoff N, Yu C, Hauschild N, Taing H, Biggs L, Goltzman D, Gregory PA, Anderson PH, Samuel MS, Galli SJ, Lopez AF, Grimbaldeston MA. Mechanisms of vitamin D₃ metabolite repression of IgE-dependent mast cell activation. The Journal of Allergy and Clinical Immunology. 133: 1356-64, 1364.e1-14. PMID 24461581 DOI: 10.1016/J.Jaci.2013.11.030  0.337
2014 Oei L, Hsu YH, Styrkarsdottir U, Eussen BH, de Klein A, Peters MJ, Halldorsson B, Liu CT, Alonso N, Kaptoge SK, Thorleifsson G, Hallmans G, Hocking LJ, Husted LB, Jameson KA, ... ... Goltzman D, et al. A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. Journal of Medical Genetics. 51: 122-31. PMID 24343915 DOI: 10.1136/Jmedgenet-2013-102064  0.337
2014 Dastani Z, Berger C, Langsetmo L, Fu L, Wong BY, Malik S, Goltzman D, Cole DE, Richards JB. In healthy adults, biological activity of vitamin D, as assessed by serum PTH, is largely independent of DBP concentrations. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 494-9. PMID 23857798 DOI: 10.1002/Jbmr.2042  0.326
2013 Krege JH, Wan X, Lentle BC, Berger C, Langsetmo L, Adachi JD, Prior JC, Tenenhouse A, Brown JP, Kreiger N, Olszynski WP, Josse RG, Goltzman D. Fracture risk prediction: importance of age, BMD and spine fracture status. Bonekey Reports. 2: 404. PMID 24228164 DOI: 10.1038/Bonekey.2013.138  0.331
2013 Guo J, Ma Z, Ma Q, Wu Z, Fan P, Zhou X, Chen L, Zhou S, Goltzman D, Miao D, Wu E. 1, 25(OH)₂D₃ inhibits hepatocellular carcinoma development through reducing secretion of inflammatory cytokines from immunocytes. Current Medicinal Chemistry. 20: 4131-41. PMID 23992309 DOI: 10.2174/09298673113209990248  0.31
2013 Zhu Q, Zhou X, Zhu M, Wang Q, Goltzman D, Karaplis A, Miao D. Endogenous parathyroid hormone-related protein compensates for the absence of parathyroid hormone in promoting bone accrual in vivo in a model of bone marrow ablation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1898-911. PMID 23716486 DOI: 10.1002/Jbmr.2000  0.422
2013 Langsetmo L, Berger C, Kreiger N, Kovacs CS, Hanley DA, Jamal SA, Whiting SJ, Genest J, Morin SN, Hodsman A, Prior JC, Lentle B, Patel MS, Brown JP, Anastasiades T, ... ... Goltzman D, et al. Calcium and vitamin D intake and mortality: results from the Canadian Multicentre Osteoporosis Study (CaMos). The Journal of Clinical Endocrinology and Metabolism. 98: 3010-8. PMID 23703722 DOI: 10.1210/Jc.2013-1516  0.346
2013 Christov M, Waikar SS, Pereira RC, Havasi A, Leaf DE, Goltzman D, Pajevic PD, Wolf M, Jüppner H. Plasma FGF23 levels increase rapidly after acute kidney injury. Kidney International. 84: 776-85. PMID 23657144 DOI: 10.1038/Ki.2013.150  0.353
2013 Shen M, Luo Y, Niu Y, Chen L, Yuan X, Goltzman D, Chen N, Miao D. 1,25(OH)2D deficiency induces temporomandibular joint osteoarthritis via secretion of senescence-associated inflammatory cytokines. Bone. 55: 400-9. PMID 23624390 DOI: 10.1016/J.Bone.2013.04.015  0.371
2013 Zheng HF, Duncan EL, Yerges-Armstrong LM, Eriksson J, Bergström U, Leo PJ, Leslie WD, Goltzman D, Blangero J, Hanley DA, Carless MA, Streeten EA, Lorentzon M, Brown MA, Spector TD, et al. Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm. Journal of Medical Genetics. 50: 473-8. PMID 23572186 DOI: 10.1136/Jmedgenet-2012-101287  0.366
2013 Liu XL, Lu YS, Gao JY, Marshall C, Xiao M, Miao DS, Karaplis A, Goltzman D, Ding J. Calcium sensing receptor absence delays postnatal brain development via direct and indirect mechanisms. Molecular Neurobiology. 48: 590-600. PMID 23564401 DOI: 10.1007/S12035-013-8448-0  0.325
2013 Quinn SJ, Thomsen ARB, Egbuna O, Pang J, Baxi K, Goltzman D, Pollak M, Brown EM. CaSR-mediated interactions between calcium and magnesium homeostasis in mice American Journal of Physiology - Endocrinology and Metabolism. 304: E724-E733. PMID 23360827 DOI: 10.1152/Ajpendo.00557.2012  0.31
2013 Quinn SJ, Thomsen ARB, Pang JL, Kantham L, Bräuner-Osborne H, Pollak M, Goltzman D, Brown EM. Interactions between calcium and phosphorus in the regulation of the production of fibroblast growth factor 23 in vivo American Journal of Physiology - Endocrinology and Metabolism. 304: E310-E320. PMID 23233539 DOI: 10.1152/Ajpendo.00460.2012  0.355
2013 Koller DL, Zheng HF, Karasik D, Yerges-Armstrong L, Liu CT, McGuigan F, Kemp JP, Giroux S, Lai D, Edenberg HJ, Peacock M, Czerwinski SA, Choh AC, McMahon G, St Pourcain B, ... ... Goltzman D, et al. Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 547-58. PMID 23074152 DOI: 10.1002/Jbmr.1796  0.337
2013 Targownik LE, Leslie WD, Davison KS, Goltzman D, Jamal SA, Kreiger N, Josse RG, Kaiser SM, Kovacs CS, Prior JC, Zhou W. Erratum: Corrigendum: The Relationship Between Proton Pump Inhibitor Use and Longitudinal Change in Bone Mineral Density: A Population-Based From the Canadian Multicentre Osteoporosis Study (CaMos) The American Journal of Gastroenterology. 108: 157-157. DOI: 10.1038/Ajg.2012.427  0.338
2013 Bilezikian JP, Bouillon R, Clemens T, Compston J, Bauer DC, Ebeling PR, Engelke K, Goltzman D, Guise T, Beur SMJD, Jüppner H, Lyons K, McCauley L, McClung MR, Miller PD, et al. Primer on the metabolic bone diseases and disorders of mineral metabolism. Journal of Bone and Joint Surgery-British Volume. 1087-1087. DOI: 10.1002/9781119266594  0.301
2012 Salehi-Tabar R, Nguyen-Yamamoto L, Tavera-Mendoza LE, Quail T, Dimitrov V, An BS, Glass L, Goltzman D, White JH. Vitamin D receptor as a master regulator of the c-MYC/MXD1 network. Proceedings of the National Academy of Sciences of the United States of America. 109: 18827-32. PMID 23112173 DOI: 10.1073/Pnas.1210037109  0.325
2012 Panda DK, Goltzman D, Karaplis AC. Defective postnatal endochondral bone development by chondrocyte-specific targeted expression of parathyroid hormone type 2 receptor. American Journal of Physiology. Endocrinology and Metabolism. 303: E1489-501. PMID 23092913 DOI: 10.1152/Ajpendo.00254.2012  0.392
2012 Zheng HF, Tobias JH, Duncan E, Evans DM, Eriksson J, Paternoster L, Yerges-Armstrong LM, Lehtimäki T, Bergström U, Kähönen M, Leo PJ, Raitakari O, Laaksonen M, Nicholson GC, Viikari J, ... ... Goltzman D, et al. WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. Plos Genetics. 8: e1002745. PMID 22792071 DOI: 10.1371/Journal.Pgen.1002745  0.357
2012 Targownik LE, Leslie WD, Davison KS, Goltzman D, Jamal SA, Kreiger N, Josse RG, Kaiser SM, Kovacs CS, Prior JC, Zhou W. The relationship between proton pump inhibitor use and longitudinal change in bone mineral density: a population-based study [corrected] from the Canadian Multicentre Osteoporosis Study (CaMos). The American Journal of Gastroenterology. 107: 1361-9. PMID 22777336 DOI: 10.1038/Ajg.2012.200  0.339
2012 Liu CT, Estrada K, Yerges-Armstrong LM, Amin N, Evangelou E, Li G, Minster RL, Carless MA, Kammerer CM, Oei L, Zhou Y, Alonso N, Dailiana Z, Eriksson J, García-Giralt N, ... ... Goltzman D, et al. Assessment of gene-by-sex interaction effect on bone mineral density. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 2051-64. PMID 22692763 DOI: 10.1002/Jbmr.1679  0.316
2012 Yan J, Sun W, Zhang J, Goltzman D, Miao D. Bone marrow ablation demonstrates that excess endogenous parathyroid hormone plays distinct roles in trabecular and cortical bone. The American Journal of Pathology. 181: 234-44. PMID 22640808 DOI: 10.1016/J.Ajpath.2012.03.038  0.409
2012 Berger C, Greene-Finestone LS, Langsetmo L, Kreiger N, Joseph L, Kovacs CS, Richards JB, Hidiroglou N, Sarafin K, Davison KS, Adachi JD, Brown J, Hanley DA, Prior JC, Goltzman D, et al. Temporal trends and determinants of longitudinal change in 25-hydroxyvitamin D and parathyroid hormone levels. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1381-9. PMID 22407786 DOI: 10.1002/Jbmr.1587  0.356
2012 Xue Y, Xiao Y, Liu J, Karaplis AC, Pollak MR, Brown EM, Miao D, Goltzman D. The calcium-sensing receptor complements parathyroid hormone-induced bone turnover in discrete skeletal compartments in mice. American Journal of Physiology. Endocrinology and Metabolism. 302: E841-51. PMID 22275754 DOI: 10.1152/Ajpendo.00599.2011  0.437
2012 Young A, Hodsman AB, Boudville N, Geddes C, Gill J, Goltzman D, Jassal SV, Klarenbach S, Knoll G, Muirhead N, Prasad GV, Treleaven D, Garg AX. Bone and mineral metabolism and fibroblast growth factor 23 levels after kidney donation. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 59: 761-9. PMID 22093959 DOI: 10.1053/J.Ajkd.2011.09.019  0.358
2012 MacNeil JA, Adachi JD, Goltzman D, Josse RG, Kovacs CS, Prior JC, Olszynski W, Davison KS, Kaiser SM. Predicting fracture using 2D finite element modelling. Medical Engineering & Physics. 34: 478-84. PMID 21959170 DOI: 10.1016/J.Medengphy.2011.08.008  0.387
2012 Zhu Y, Zhou R, Yang R, Zhang Z, Bai Y, Chang F, Li L, Sokabe M, Goltzman D, Miao D, Chen L. Abnormal neurogenesis in the dentate gyrus of adult mice lacking 1,25-dihydroxy vitamin D3 (1,25-(OH)2 D3). Hippocampus. 22: 421-33. PMID 21125584 DOI: 10.1002/Hipo.20908  0.343
2012 Zheng⁎ H, Duncan E, Eriksson J, Bergström U, Yerges-Armstrong L, Leo P, Vandenput L, Nicholson G, Ladouceur M, Prince R, Leslie W, Eisman J, Goltzman D, Jones G, Xiao Y, et al. The 7Q31 locus, containing WNT16, is associated with bone mineral density, osteoporotic fracture and bone strength Bone. 50: S33-S34. DOI: 10.1016/J.Bone.2012.02.086  0.388
2012 Zheng H, Duncan E, Eriksson J, Bergström U, Yerges-Armstrong LM, Leo PJ, Vandenput L, Nicholson G, Ladouceur M, Prince RL, Leslie WD, Eisman JA, Goltzman D, Jones G, Xiao Y, et al. WNT16 is associated with bone mineral density, osteoporotic fracture and bone strength : a large-scale meta-analysis of genomewide association studies Osteoporosis International. 23. DOI: 10.1007/S00198-012-1924-Y  0.383
2011 Liu J, Lv F, Sun W, Tao C, Ding G, Karaplis A, Brown E, Goltzman D, Miao D. The abnormal phenotypes of cartilage and bone in calcium-sensing receptor deficient mice are dependent on the actions of calcium, phosphorus, and PTH. Plos Genetics. 7: e1002294. PMID 21966280 DOI: 10.1371/Journal.Pgen.1002294  0.419
2011 Ren Y, Liu B, Feng Y, Shu L, Cao X, Karaplis A, Goltzman D, Miao D. Endogenous PTH deficiency impairs fracture healing and impedes the fracture-healing efficacy of exogenous PTH(1-34). Plos One. 6: e23060. PMID 21829585 DOI: 10.1371/Journal.Pone.0023060  0.398
2011 Ji J, Lu R, Zhou X, Xue Y, Shi C, Goltzman D, Miao D. 1,25-Dihydroxyvitamin D₃ contributes to regulating mammary calcium transport and modulates neonatal skeletal growth and turnover cooperatively with calcium. American Journal of Physiology. Endocrinology and Metabolism. 301: E889-900. PMID 21791625 DOI: 10.1152/Ajpendo.00173.2011  0.311
2011 Leslie WD, Kovacs CS, Olszynski WP, Towheed T, Kaiser SM, Prior JC, Josse RG, Jamal SA, Kreiger N, Goltzman D. Spine-hip T-score difference predicts major osteoporotic fracture risk independent of FRAX(®): a population-based report from CAMOS. Journal of Clinical Densitometry : the Official Journal of the International Society For Clinical Densitometry. 14: 286-93. PMID 21723768 DOI: 10.1016/J.Jocd.2011.04.011  0.325
2011 Goltzman D. LRP5, serotonin, and bone: complexity, contradictions, and conundrums. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1997-2001. PMID 21713997 DOI: 10.1002/Jbmr.462  0.334
2011 Shu L, Ji J, Zhu Q, Cao G, Karaplis A, Pollak MR, Brown E, Goltzman D, Miao D. The calcium-sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone in neonates. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1057-71. PMID 21542007 DOI: 10.1002/Jbmr.300  0.391
2011 Chen L, Liu H, Sun W, Bai X, Karaplis AC, Goltzman D, Miao D. Fibroblast growth factor 23 overexpression impacts negatively on dentin mineralization and dentinogenesis in mice. Clinical and Experimental Pharmacology & Physiology. 38: 395-402. PMID 21488937 DOI: 10.1111/J.1440-1681.2011.05526.X  0.352
2011 Langsetmo L, Hanley DA, Prior JC, Barr SI, Anastassiades T, Towheed T, Goltzman D, Morin S, Poliquin S, Kreiger N. Dietary patterns and incident low-trauma fractures in postmenopausal women and men aged ≥50 y: A population-based cohort study American Journal of Clinical Nutrition. 93: 192-199. PMID 21068350 DOI: 10.3945/Ajcn.110.002956  0.331
2011 Greene-Finestone LS, Berger C, de Groh M, Hanley DA, Hidiroglou N, Sarafin K, Poliquin S, Krieger J, Richards JB, Goltzman D. 25-Hydroxyvitamin D in Canadian adults: biological, environmental, and behavioral correlates. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 22: 1389-99. PMID 20730415 DOI: 10.1007/S00198-010-1362-7  0.303
2011 Targownik L, Leslie W, Davidson S, Goltzman D, Jamal S, Josse R, Kreiger N, Kaiser S, Kovacs C, Prior J. Proton Pump Inhibitors Are Associated with Decreased Bone Mineral Density: 1089 The American Journal of Gastroenterology. 106. DOI: 10.14309/00000434-201110002-01089  0.348
2010 Sun W, Xie H, Ji J, Zhou X, Goltzman D, Miao D. Defective female reproductive function in 1,25(OH)2D-deficient mice results from indirect effect mediated by extracellular calcium and/or phosphorus. American Journal of Physiology. Endocrinology and Metabolism. 299: E928-35. PMID 20807842 DOI: 10.1152/Ajpendo.00378.2010  0.334
2010 Nguyen-Yamamoto L, Bolivar I, Strugnell SA, Goltzman D. Comparison of Active Vitamin D Compounds and a Calcimimetic in Mineral Homeostasis Journal of the American Society of Nephrology. 21: 1713-1723. PMID 20651168 DOI: 10.1681/Asn.2009050531  0.397
2010 Goltzman D. Emerging roles for calcium-regulating hormones beyond osteolysis Trends in Endocrinology and Metabolism. 21: 512-518. PMID 20605729 DOI: 10.1016/J.Tem.2010.04.002  0.438
2010 Langsetmo L, Morin S, Kovacs CS, Kreiger N, Josse R, Adachi JD, Papaioannou A, Goltzman D, Hanley DA, Olszynski WP, Prior J, Jamal SA. Determining whether women with osteopenic bone mineral density have low, moderate, or high clinical fracture risk Menopause. 17: 1010-1016. PMID 20555289 DOI: 10.1097/Gme.0B013E3181Da4B7D  0.333
2010 Zhou W, Langsetmo L, Berger C, Adachi JD, Papaioannou A, Ioannidis G, Webber C, Atkinson SA, Olszynski WP, Brown JP, Hanley DA, Josse R, Kreiger N, Prior J, Kaiser S, ... ... Goltzman D, et al. Normative bone mineral density z-scores for Canadians aged 16 to 24 years: the Canadian Multicenter Osteoporosis Study. Journal of Clinical Densitometry : the Official Journal of the International Society For Clinical Densitometry. 13: 267-76. PMID 20554232 DOI: 10.1016/J.Jocd.2010.04.005  0.33
2010 Berger C, Goltzman D, Langsetmo L, Joseph L, Jackson S, Kreiger N, Tenenhouse A, Davison KS, Josse RG, Prior JC, Hanley DA. Peak bone mass from longitudinal data: implications for the prevalence, pathophysiology, and diagnosis of osteoporosis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1948-57. PMID 20499378 DOI: 10.1002/Jbmr.95  0.326
2010 Langsetmo L, Leslie WD, Zhou W, Goltzman D, Kovacs CS, Prior JC, Josse R, Olszynski WP, Davison KS, Anastassiades T, Towheed T, Hanley DA, Kaiser S, Kreiger N. Using the same bone density reference database for men and women provides a simpler estimation of fracture risk Journal of Bone and Mineral Research. 25: 2108-2114. PMID 20499356 DOI: 10.1002/Jbmr.112  0.34
2010 Xu M, Choudhary S, Voznesensky O, Gao Q, Adams D, Diaz-Doran V, Wu Q, Goltzman D, Raisz LG, Pilbeam CC. Basal bone phenotype and increased anabolic responses to intermittent parathyroid hormone in healthy male COX-2 knockout mice. Bone. 47: 341-52. PMID 20471507 DOI: 10.1016/J.Bone.2010.05.006  0.395
2010 Goltzman D. Vitamin D action : Lessons learned from genetic mouse models. Annals of the New York Academy of Sciences. 1192: 145-152. PMID 20392230 DOI: 10.1111/J.1749-6632.2009.05226.X  0.376
2010 Goltzman D. Do calcimimetics directly alter bone remodeling American Journal of Physiology-Renal Physiology. 298. PMID 20237238 DOI: 10.1152/Ajprenal.00147.2010  0.369
2010 Richard C, Huo R, Samadfam R, Bolivar I, Miao D, Brown EM, Hendy GN, Goltzman D. The calcium-sensing receptor and 25-hydroxyvitamin D-1alpha-hydroxylase interact to modulate skeletal growth and bone turnover. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1627-36. PMID 20200973 DOI: 10.1002/Jbmr.58  0.439
2010 Sun W, Sun W, Liu J, Zhou X, Xiao Y, Karaplis A, Pollak MR, Brown E, Goltzman D, Miao D. Alterations in phosphorus, calcium and PTHrP contribute to defects in dental and dental alveolar bone formation in calcium-sensing receptor-deficient mice. Development (Cambridge, England). 137: 985-92. PMID 20150282 DOI: 10.1242/Dev.045898  0.416
2010 Langsetmo L, Poliquin S, Hanley DA, Prior JC, Barr S, Anastassiades T, Towheed T, Goltzman D, Kreiger N. Dietary patterns in Canadian men and women ages 25 and older: relationship to demographics, body mass index, and bone mineral density. Bmc Musculoskeletal Disorders. 11: 20. PMID 20109205 DOI: 10.1186/1471-2474-11-20  0.318
2010 Zhang HW, Ding J, Jin JL, Guo J, Liu JN, Karaplis A, Goltzman D, Miao D. Defects in mesenchymal stem cell self-renewal and cell fate determination lead to an osteopenic phenotype in Bmi-1 null mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 640-52. PMID 19653817 DOI: 10.1359/Jbmr.090812  0.395
2010 Ji J, Miao D, He B, Karaplis A, Goltzman D. The coordinated action of parathyroid hormone and parathyroid hormone related peptide is essential for normal fetal axial skeletal development Bone. 47: S363. DOI: 10.1016/J.Bone.2010.09.095  0.307
2009 Jamal SA, Goltzman D, Hanley DA, Papaioannou A, Prior JC, Josse RG. Retraction to: Nitrate use and changes in bone mineral density: the Canadian Multicentre Osteoporosis Study. Osteoporosis International. 28: 421-421. PMID 27909783 DOI: 10.1007/S00198-016-3843-9  0.374
2009 Samadfam R, Richard C, Nguyen-Yamamoto L, Bolivar I, Goltzman D. Bone formation regulates circulating concentrations of fibroblast growth factor 23. Endocrinology. 150: 4835-45. PMID 19819968 DOI: 10.1210/En.2009-0472  0.449
2009 Kantham L, Quinn SJ, Egbuna OI, Baxi K, Butters R, Pang JL, Pollak MR, Goltzman D, Brown EM. The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretion. American Journal of Physiology. Endocrinology and Metabolism. 297: E915-23. PMID 19797241 DOI: 10.1152/Ajpendo.00315.2009  0.315
2009 Liu H, Guo J, Wang L, Chen N, Karaplis A, Goltzman D, Miao D. Distinctive anabolic roles of 1,25-dihydroxyvitamin D(3) and parathyroid hormone in teeth and mandible versus long bones. The Journal of Endocrinology. 203: 203-13. PMID 19713218 DOI: 10.1677/Joe-09-0247  0.417
2009 Panda D, Goltzman D, Jüppner H, Karaplis AC. TIP39/parathyroid hormone type 2 receptor signaling is a potent inhibitor of chondrocyte proliferation and differentiation. American Journal of Physiology. Endocrinology and Metabolism. 297: E1125-36. PMID 19706789 DOI: 10.1152/Ajpendo.00254.2009  0.329
2009 Liu P, Bai X, Wang H, Karaplis A, Goltzman D, Miao D. Hypophosphatemia-mediated hypotension in transgenic mice overexpressing human FGF-23. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1514-20. PMID 19684183 DOI: 10.1152/Ajpheart.00581.2009  0.311
2009 Egbuna O, Quinn S, Kantham L, Butters R, Pang J, Pollak M, Goltzman D, Brown E. The full-length calcium-sensing receptor dampens the calcemic response to 1alpha,25(OH)2 vitamin D3 in vivo independently of parathyroid hormone. American Journal of Physiology. Renal Physiology. 297: F720-8. PMID 19474191 DOI: 10.1152/Ajprenal.00164.2009  0.344
2009 Langsetmo L, Goltzman D, Kovacs CS, Adachi JD, Hanley DA, Kreiger N, Josse R, Papaioannou A, Olszynski WP, Jamal SA, Tenenhouse A, Poliquin S, Godmaire S, Berger C, Joyce C, et al. Repeat low-trauma fractures occur frequently among men and women who have osteopenic BMD Journal of Bone and Mineral Research. 24: 1515-1522. PMID 19338456 DOI: 10.1359/Jbmr.090319  0.306
2009 Bai X, Dinghong Q, Miao D, Goltzman D, Karaplis AC. Klotho ablation converts the biochemical and skeletal alterations in FGF23 (R176Q) transgenic mice to a Klotho-deficient phenotype. American Journal of Physiology. Endocrinology and Metabolism. 296: E79-88. PMID 18984852 DOI: 10.1152/Ajpendo.90539.2008  0.349
2009 Berger C, Langsetmo L, Joseph L, Hanley DA, Davison KS, Josse RG, Prior JC, Kreiger N, Tenenhouse A, Goltzman D, Poliquin S, Godmaire S, Joyce C, Kovacs C, Sheppard E, et al. Association between change in BMD and fragility fracture in women and men Journal of Bone and Mineral Research. 24: 361-370. PMID 18847328 DOI: 10.1359/Jbmr.081004  0.333
2009 Cao G, Gu Z, Ren Y, Shu L, Tao C, Karaplis A, Goltzman D, Miao D. Parathyroid hormone contributes to regulating milk calcium content and modulates neonatal bone formation cooperatively with calcium. Endocrinology. 150: 561-9. PMID 18832101 DOI: 10.1210/En.2008-0654  0.354
2009 Jamal SA, Goltzman D, Hanley DA, Papaioannou A, Prior JC, Josse RG. Nitrate use and changes in bone mineral density: the Canadian Multicentre Osteoporosis Study. Osteoporosis International. 20: 737-744. PMID 18800179 DOI: 10.1007/S00198-008-0727-7  0.332
2009 Bernier SM, Goltzman D. Regulation of expression of the chondrocytic phenotype in a skeletal cell line (CFK2) in vitro Journal of Bone and Mineral Research. 8: 475-484. PMID 8475797 DOI: 10.1002/Jbmr.5650080412  0.318
2009 Rouleau MF, Warshawsky H, Marks SC, Goltzman D. Calcitonin receptor binding as a marker of osteoclast heterogeneity in osteopetrotic rodents. Journal of Bone and Mineral Research. 1: 543-553. PMID 2845732 DOI: 10.1002/Jbmr.5650010609  0.356
2009 Rouleau MF, Mitchell J, Goltzman D. Characterization of the major parathyroid hormone target cell in the endosteal metaphysis of rat long bones. Journal of Bone and Mineral Research. 5: 1043-1053. PMID 2080716 DOI: 10.1002/Jbmr.5650051008  0.351
2009 Goltzman D. Studies of antiresorptive agents plus parathyroid hormone in the treatment of bone loss Bone. 44. DOI: 10.1016/J.Bone.2009.03.015  0.365
2009 Goltzman D. 25-Hydroxyvitamin D-1α Hydroxylase: Studies in Mouse Models and Implications for Human Disease Clinical Reviews in Bone and Mineral Metabolism. 7: 126-133. DOI: 10.1007/978-1-60327-303-9_39  0.406
2008 Miao D, Su H, He B, Gao J, Xia Q, Zhu M, Gu Z, Goltzman D, Karaplis AC. Severe growth retardation and early lethality in mice lacking the nuclear localization sequence and C-terminus of PTH-related protein. Proceedings of the National Academy of Sciences of the United States of America. 105: 20309-14. PMID 19091948 DOI: 10.1073/Pnas.0805690105  0.392
2008 Langsetmo L, Hanley DA, Kreiger N, Jamal SA, Prior J, Adachi JD, Davison KS, Kovacs C, Anastassiades T, Tenenhouse A, Goltzman D. Geographic variation of bone mineral density and selected risk factors for prediction of incident fracture among Canadians 50 and older. Bone. 43: 672-8. PMID 18640295 DOI: 10.1016/J.Bone.2008.06.009  0.337
2008 Berger C, Langsetmo L, Joseph L, Hanley DA, Davison KS, Josse R, Kreiger N, Tenenhouse A, Goltzman D, Poliquin S, Godmaire S, Joyce C, Kovacs C, Sheppard E, Kirkland S, et al. Change in bone mineral density as a function of age in women and men and association with the use of antiresorptive agents Cmaj. 178: 1660-1668. PMID 18559803 DOI: 10.1503/Cmaj.071416  0.377
2008 Gupta A, Välimäki VV, J Välimäki M, Löyttyniemi E, Richard M, L Bukka P, Goltzman D, Karaplis AC. Variable number of tandem repeats polymorphism in parathyroid hormone-related protein as predictor of peak bone mass in young healthy Finnish males. European Journal of Endocrinology / European Federation of Endocrine Societies. 158: 755-64. PMID 18426836 DOI: 10.1530/Eje-07-0886  0.402
2008 Goltzman D. Studies on the mechanisms of the skeletal anabolic action of endogenous and exogenous parathyroid hormone. Archives of Biochemistry and Biophysics. 473: 218-224. PMID 18358824 DOI: 10.1016/J.Abb.2008.03.003  0.437
2008 Samadfam R, Xia Q, Miao D, Hendy GN, Goltzman D. Exogenous PTH and endogenous 1,25-dihydroxyvitamin D are complementary in inducing an anabolic effect on bone. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 1257-66. PMID 18348699 DOI: 10.1359/Jbmr.080318  0.433
2008 Ji J, Zhou X, Xue Y, Goltzman D, Miao D. 1,25(OH)2D3 contributes to regulating milk calcium content and modulates neonatal bone formation cooperatively with calcium Bone. 43. DOI: 10.1016/J.Bone.2008.08.053  0.374
2008 Shu L, Cao G, Ren Y, Karaplis A, Goltzman D, Miao D. The calcium sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone Bone. 43: S49. DOI: 10.1016/J.Bone.2008.08.033  0.374
2008 Sun W, Liu J, Karaplis A, Goltzman D, Miao D. Alterations in phosphorus, calcium and PTHrP appear to contribute to defects of dental formation in calcium-sensing receptor deficient mice Bone. 43: S49. DOI: 10.1016/J.Bone.2008.08.032  0.319
2008 Liu J, Tao C, Sun W, Karaplis A, Goltzman D, Miao D. The abnormal phenotypes of cartilage and bone in calcium-sensing receptor deficient mice are dependent on the actions of calcium, phosphorus and parathyroid hormone Bone. 43: S31. DOI: 10.1016/J.Bone.2008.07.034  0.394
2007 Bai X, Miao D, Goltzman D, Karaplis AC. Early lethality in Hyp mice with targeted deletion of Pth gene. Endocrinology. 148: 4974-83. PMID 17615144 DOI: 10.1210/En.2007-0243  0.353
2007 Samadfam R, Xia Q, Goltzman D. Pretreatment with Anticatabolic Agents Blunts But Does Not Eliminate the Skeletal Anabolic Response to Parathyroid Hormone in Oophorectomized Mice Endocrinology. 148: 2778-2787. PMID 17379647 DOI: 10.1210/En.2006-1475  0.428
2007 Gao J, Tiwari-Pandey R, Samadfam R, Yang Y, Miao D, Karaplis AC, Sairam MR, Goltzman D. Altered ovarian function affects skeletal homeostasis independent of the action of follicle-stimulating hormone. Endocrinology. 148: 2613-21. PMID 17332067 DOI: 10.1210/En.2006-1404  0.42
2007 Goltzman D. Use of genetically modified mice to examine the skeletal anabolic activity of vitamin D. The Journal of Steroid Biochemistry and Molecular Biology. 103: 587-591. PMID 17254773 DOI: 10.1016/J.Jsbmb.2006.12.087  0.408
2006 Samadfam R, Xia Q, Goltzman D. Co-Treatment of PTH With Osteoprotegerin or Alendronate Increases Its Anabolic Effect on the Skeleton of Oophorectomized Mice Journal of Bone and Mineral Research. 22: 55-63. PMID 17014384 DOI: 10.1359/Jbmr.060915  0.416
2006 Davison KS, Siminoski K, Adachi JD, Hanley DA, Goltzman D, Hodsman AB, Josse R, Kaiser S, Olszynski WP, Papaioannou A, Ste-Marie LG, Kendler DL, Tenenhouse A, Brown JP. Bone strength: the whole is greater than the sum of its parts. Seminars in Arthritis and Rheumatism. 36: 22-31. PMID 16887465 DOI: 10.1016/J.Semarthrit.2006.04.002  0.359
2006 Davison KS, Siminoski K, Adachi JD, Hanley DA, Goltzman D, Hodsman AB, Josse R, Kaiser S, Olszynski WP, Papaioannou A, Ste-Marie LG, Kendler DL, Tenenhouse A, Brown JP. The effects of antifracture therapies on the components of bone strength: assessment of fracture risk today and in the future. Seminars in Arthritis and Rheumatism. 36: 10-21. PMID 16887464 DOI: 10.1016/J.Semarthrit.2006.04.001  0.396
2006 Xue Y, Karaplis AC, Hendy GN, Goltzman D, Miao D. Exogenous 1,25-dihydroxyvitamin D3 exerts a skeletal anabolic effect and improves mineral ion homeostasis in mice that are homozygous for both the 1alpha-hydroxylase and parathyroid hormone null alleles. Endocrinology. 147: 4801-10. PMID 16857747 DOI: 10.1210/En.2006-0403  0.43
2006 Cranney A, Papaioannou A, Zytaruk N, Hanley D, Adachi J, Goltzman D, Murray T, Hodsman A. Parathyroid hormone for the treatment of osteoporosis: a systematic review Canadian Medical Association Journal. 175: 52-59. PMID 16818910 DOI: 10.1503/Cmaj.050929  0.345
2006 Richards JB, Joseph L, Schwartzman K, Kreiger N, Tenenhouse A, Goltzman D. The effect of cyclooxygenase-2 inhibitors on bone mineral density: results from the Canadian Multicentre Osteoporosis Study. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 17: 1410-9. PMID 16791706 DOI: 10.1007/S00198-006-0142-X  0.371
2006 Hendy GN, Hruska KA, Mathew S, Goltzman D. New insights into mineral and skeletal regulation by active forms of vitamin D Kidney International. 69: 218-223. PMID 16408109 DOI: 10.1038/Sj.Ki.5000091  0.423
2005 Xue Y, Zhang Z, Karaplis AC, Hendy GN, Goltzman D, Miao D. Exogenous PTH-related protein and PTH improve mineral and skeletal status in 25-hydroxyvitamin D-1alpha-hydroxylase and PTH double knockout mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1766-77. PMID 16160734 DOI: 10.1359/Jbmr.050608  0.434
2005 Miao D, He B, Jiang Y, Kobayashi T, Sorocéanu MA, Zhao J, Su H, Tong X, Amizuka N, Gupta A, Genant HK, Kronenberg HM, Goltzman D, Karaplis AC. Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34. The Journal of Clinical Investigation. 115: 2402-11. PMID 16138191 DOI: 10.1172/Jci24918  0.424
2005 Hendy GN, Goltzman D. Does calcitriol have actions independent from the vitamin D receptor in maintaining skeletal and mineral homeostasis? Current Opinion in Nephrology and Hypertension. 14: 350-4. PMID 15931003 DOI: 10.1097/01.Mnh.0000172721.44875.24  0.322
2005 Xue Y, Karaplis AC, Hendy GN, Goltzman D, Miao D. Genetic models show that parathyroid hormone and 1,25-dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development. Human Molecular Genetics. 14: 1515-28. PMID 15843402 DOI: 10.1093/Hmg/Ddi160  0.432
2005 Rabbani SA, Khalili P, Arakelian A, Pizzi H, Chen G, Goltzman D. Regulation of parathyroid hormone-related peptide by estradiol: Effect on tumor growth and metastasis in vitro and in vivo Endocrinology. 146: 2885-2894. PMID 15831570 DOI: 10.1210/En.2005-0062  0.305
2005 Xu M, Choudhary S, Goltzman D, Ledgard F, Adams D, Gronowicz G, Koczon-Jaremko B, Raisz L, Pilbeam C. Do cyclooxygenase-2 knockout mice have primary hyperparathyroidism? Endocrinology. 146: 1843-53. PMID 15625247 DOI: 10.1210/En.2004-0734  0.375
2004 Sorocéanu MA, Miao D, Bai XY, Su H, Goltzman D, Karaplis AC. Rosiglitazone impacts negatively on bone by promoting osteoblast/osteocyte apoptosis. The Journal of Endocrinology. 183: 203-16. PMID 15525588 DOI: 10.1677/Joe.1.05723  0.418
2004 Goltzman D, Miao D, Panda DK, Hendy GN. Effects of calcium and of the Vitamin D system on skeletal and calcium homeostasis: lessons from genetic models. The Journal of Steroid Biochemistry and Molecular Biology. 89: 485-9. PMID 15225825 DOI: 10.1016/J.Jsbmb.2004.03.058  0.375
2004 Miao D, Li J, Xue Y, Su H, Karaplis AC, Goltzman D. Parathyroid hormone-related peptide is required for increased trabecular bone volume in parathyroid hormone-null mice. Endocrinology. 145: 3554-62. PMID 15090463 DOI: 10.1210/En.2003-1695  0.426
2004 Miao D, Bai X, Panda DK, Karaplis AC, Goltzman D, McKee MD. Cartilage abnormalities are associated with abnormal Phex expression and with altered matrix protein and MMP-9 localization in Hyp mice. Bone. 34: 638-47. PMID 15050894 DOI: 10.1016/J.Bone.2003.12.015  0.347
2004 Miao D, Liu H, Plut P, Niu M, Huo R, Goltzman D, Henderson JE. Impaired endochondral bone development and osteopenia in Gli2-deficient mice. Experimental Cell Research. 294: 210-22. PMID 14980515 DOI: 10.1016/J.Yexcr.2003.10.021  0.422
2004 Amizuka N, Davidson D, Liu H, Valverde-Franco G, Chai S, Maeda T, Ozawa H, Hammond V, Ornitz DM, Goltzman D, Henderson JE. Signalling by fibroblast growth factor receptor 3 and parathyroid hormone-related peptide coordinate cartilage and bone development. Bone. 34: 13-25. PMID 14751559 DOI: 10.1016/J.Bone.2003.08.009  0.395
2004 Panda DK, Miao D, Bolivar I, Li J, Huo R, Hendy GN, Goltzman D. Inactivation of the 25-hydroxyvitamin D 1alpha-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasis. The Journal of Biological Chemistry. 279: 16754-66. PMID 14739296 DOI: 10.1074/Jbc.M310271200  0.369
2004 Miao D, He B, Lanske B, Bai XY, Tong XK, Hendy GN, Goltzman D, Karaplis AC. Skeletal abnormalities in Pth-null mice are influenced by dietary calcium. Endocrinology. 145: 2046-53. PMID 14701672 DOI: 10.1210/En.2003-1097  0.441
2004 Valverde-Franco G, Liu H, Davidson D, Chai S, Valderrama-Carvajal H, Goltzman D, Ornitz DM, Henderson JE. Defective bone mineralization and osteopenia in young adult FGFR3-/- mice. Human Molecular Genetics. 13: 271-84. PMID 14681299 DOI: 10.1093/Hmg/Ddh034  0.419
2004 Amizuka N, Henderson JE, White JH, Oda K, Li M, Nozawa-Inoue K, Kawano Y, Suzuki A, Karaplis AC, Goltzman D, Maeda T. Morphological Approach to Biological Action of PTHrP and Vitamin D3 on Endochondral Ossification Journal of Oral Biosciences. 46: 79-96. DOI: 10.1016/S1349-0079(04)80020-3  0.429
2003 Thomas G, Moffatt P, Salois P, Gaumond MH, Gingras R, Godin E, Miao D, Goltzman D, Lanctôt C. Osteocrin, a novel bone-specific secreted protein that modulates the osteoblast phenotype. The Journal of Biological Chemistry. 278: 50563-71. PMID 14523025 DOI: 10.1074/Jbc.M307310200  0.419
2003 Chan GK, Miao D, Deckelbaum R, Bolivar I, Karaplis A, Goltzman D. Parathyroid hormone-related peptide interacts with bone morphogenetic protein 2 to increase osteoblastogenesis and decrease adipogenesis in pluripotent C3H10T 1/2 mesenchymal cells. Endocrinology. 144: 5511-20. PMID 12960089 DOI: 10.1210/En.2003-0273  0.39
2003 Kos CH, Karaplis AC, Peng JB, Hediger MA, Goltzman D, Mohammad KS, Guise TA, Pollak MR. The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone. The Journal of Clinical Investigation. 111: 1021-8. PMID 12671051 DOI: 10.1172/Jci17416  0.361
2003 Bai XY, Miao D, Goltzman D, Karaplis AC. The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency. The Journal of Biological Chemistry. 278: 9843-9. PMID 12519781 DOI: 10.1074/Jbc.M210490200  0.348
2002 Bai X, Miao D, Panda D, Grady S, McKee MD, Goltzman D, Karaplis AC. Partial rescue of the Hyp phenotype by osteoblast-targeted PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) expression. Molecular Endocrinology (Baltimore, Md.). 16: 2913-25. PMID 12456809 DOI: 10.1210/Me.2002-0113  0.386
2002 Goltzman D. Discoveries, drugs and skeletal disorders Nature Reviews Drug Discovery. 1: 784-796. PMID 12360256 DOI: 10.1038/Nrd916  0.367
2002 Lin R, Amizuka N, Sasaki T, Aarts MM, Ozawa H, Goltzman D, Henderson JE, White JH. 1Alpha,25-dihydroxyvitamin D3 promotes vascularization of the chondro-osseous junction by stimulating expression of vascular endothelial growth factor and matrix metalloproteinase 9. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 1604-12. PMID 12211430 DOI: 10.1359/Jbmr.2002.17.9.1604  0.33
2002 Miao D, He B, Karaplis AC, Goltzman D. Parathyroid hormone is essential for normal fetal bone formation. The Journal of Clinical Investigation. 109: 1173-82. PMID 11994406 DOI: 10.1172/Jci14817  0.435
2002 Minagawa M, Yasuda T, Watanabe T, Minamitani K, Takahashi Y, Goltzman D, White JH, Hendy GN, Kohno Y. Association between AAAG repeat polymorphism in the P3 promoter of the human parathyroid hormone (PTH)/PTH-related peptide receptor gene and adult height, urinary pyridinoline excretion, and promoter activity. The Journal of Clinical Endocrinology and Metabolism. 87: 1791-6. PMID 11932319 DOI: 10.1210/Jcem.87.4.8419  0.355
2001 Miao D, Bai X, Panda D, McKee MD, Karaplis AC, Goltzman D. Osteomalacia in Hyp Mice Is Associated with Abnormal Phex Expression and with Altered Bone Matrix Protein Expression and Deposition* *This work was support by Grants MT-5775 (to D.G.) and GR-13297 (to A.C.K.) from the Medical Research Council of Canada, Grant 00731 (to D.G.) from the NCI of Canada, and Grant MT-11360 (to M.D.M.) from the Canadian Institutes for Health Research. Endocrinology. 142: 926-939. PMID 28201145 DOI: 10.1210/Endo.142.2.7976  0.419
2001 Goltzman D. Extending preclinical models of skeletal manifestations of malignancy to the clinical setting. Seminars in Oncology. 28: 9-14. PMID 11544570 DOI: 10.1016/S0093-7754(01)90226-X  0.367
2001 Carpio L, Gladu J, Goltzman D, Rabbani SA. Induction of osteoblast differentiation indexes by PTHrP in MG-63 cells involves multiple signaling pathways. American Journal of Physiology. Endocrinology and Metabolism. 281: E489-99. PMID 11500304 DOI: 10.1152/Ajpendo.2001.281.3.E489  0.302
2001 Miao D, Tong XK, Chan GK, Panda D, McPherson PS, Goltzman D. Parathyroid hormone-related peptide stimulates osteogenic cell proliferation through protein kinase C activation of the Ras/mitogen-activated protein kinase signaling pathway. The Journal of Biological Chemistry. 276: 32204-13. PMID 11402023 DOI: 10.1074/Jbc.M101084200  0.337
2001 Goltzman D, White J, Kremer R. Studies of the effects of 1,25-dihydroxyvitamin D on skeletal and calcium homeostasis and on inhibition of tumor cell growth Journal of Steroid Biochemistry and Molecular Biology. 76: 43-47. PMID 11384862 DOI: 10.1016/S0960-0760(00)00146-1  0.396
2001 Goltzman D. Osteolysis and cancer. Journal of Clinical Investigation. 107: 1219-1220. PMID 11375409 DOI: 10.1172/Jci13073  0.384
2001 He B, Deckelbaum RA, Miao D, Lipman ML, Pollak M, Goltzman D, Karaplis AC. Tissue-specific targeting of the pthrp gene: the generation of mice with floxed alleles. Endocrinology. 142: 2070-7. PMID 11316774 DOI: 10.1210/Endo.142.5.8146  0.338
2001 Panda DK, Kawas SA, Seldin MF, Hendy GN, Goltzman D. 25-Hydroxyvitamin D 1α-hydroxylase: Structure of the mouse gene, chromosomal assignment, and developmental expression Journal of Bone and Mineral Research. 16: 46-56. PMID 11149489 DOI: 10.1359/Jbmr.2001.16.1.46  0.328
2000 Karaplis AC, Goltzman D. PTH and PTHrP effects on the skeleton. Reviews in Endocrine & Metabolic Disorders. 1: 331-41. PMID 11706747 DOI: 10.1023/A:1026526703898  0.319
2000 Weber MH, Goltzman D, Kostenuik P, Rabbani S, Singh G, Orr FW. Mechanisms of tumor metastasis to bone. Critical Reviews in Eukaryotic Gene Expression. 10: 281-302. PMID 11272470 DOI: 10.1615/Critreveukargeneexpr.V10.I3-4.60  0.394
2000 Abdaimi KE, Papavasiliou V, Goltzman D, Kremer R. Expression and regulation of parathyroid hormone-related peptide in normal and malignant melanocytes American Journal of Physiology-Cell Physiology. 279: 1230-1238. PMID 11003603 DOI: 10.1152/Ajpcell.2000.279.4.C1230  0.301
2000 Amizuka N, Henderson JE, White JH, Karaplis AC, Goltzman D, Sasaki T, Ozawa H. Recent studies on the biological action of parathyroid hormone (PTH)-related peptide (PTHrP) and PTH/PTHrP receptor in cartilage and bone Histology and Histopathology. 15: 957-970. PMID 10963138 DOI: 10.14670/Hh-15.957  0.422
2000 Adachi JD, Olszynski WP, Hanley DA, Hodsman AB, Kendler DL, Siminoski KG, Brown J, Cowden EA, Goltzman D, Ioannidis G, Josse RG, Ste-Marie LG, Tenenhouse AM, Davison KS, Blocka KL, et al. Management of corticosteroid-induced osteoporosis. Seminars in Arthritis and Rheumatism. 29: 228-51. PMID 10707991 DOI: 10.1016/S0049-0172(00)80011-6  0.344
2000 Henderson JE, Naski MC, Aarts MM, Wang D, Cheng L, Goltzman D, Ornitz DM. Expression of FGFR3 with the G380R achondroplasia mutation inhibits proliferation and maturation of CFK2 chondrocytic cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 15: 155-65. PMID 10646125 DOI: 10.1359/Jbmr.2000.15.1.155  0.321
2000 Goltzman D, White JH. Developmental and tissue-specific regulation of parathyroid hormone (PTH)/PTH-related peptide receptor gene expression. Critical Reviews in Eukaryotic Gene Expression. 10: 135. DOI: 10.1615/Critreveukargeneexpr.V10.I2.30  0.363
1999 Fraher LJ, Avram R, Watson PH, Hendy GN, Henderson JE, Chong KL, Goltzman D, Morley P, Willick GE, Whitfield JF, Hodsman AB. Comparison of the biochemical responses to human parathyroid hormone-(1-31)NH2 and hPTH-(1-34) in healthy humans Journal of Clinical Endocrinology and Metabolism. 84: 2739-2743. PMID 10443671 DOI: 10.1210/Jcem.84.8.5891  0.353
1999 Rabbani SA, Gladu J, Harakidas P, Jamison B, Goltzman D. Over-production of parathyroid hormone-related peptide results in increased osteolytic skeletal metastasis by prostate cancer cells in vivo. International Journal of Cancer. 80: 257-64. PMID 9935208 DOI: 10.1002/(Sici)1097-0215(19990118)80:2<257::Aid-Ijc15>3.0.Co;2-3  0.325
1999 Amizuka N, Kwan MY, Goltzman D, Ozawa H, White JH. Vitamin D3 differentially regulates parathyroid hormone/parathyroid hormone-related peptide receptor expression in bone and cartilage. The Journal of Clinical Investigation. 103: 373-81. PMID 9927498 DOI: 10.1172/Jci3265  0.377
1999 Palcy S, Goltzman D. Protein kinase signalling pathways involved in the up-regulation of the rat alpha1(I) collagen gene by transforming growth factor beta1 and bone morphogenetic protein 2 in osteoblastic cells. Biochemical Journal. 343: 21-27. DOI: 10.1042/Bj3430021  0.317
1998 Bettoun JD, Minagawa M, Hendy GN, Alpert LC, Goodyer CG, Goltzman D, White JH. Developmental upregulation of human parathyroid hormone (PTH)/PTH-related peptide receptor gene expression from conserved and human-specific promoters. The Journal of Clinical Investigation. 102: 958-67. PMID 9727064 DOI: 10.1172/Jci3678  0.323
1998 Meerovitch K, Wing S, Goltzman D. Proparathyroid Hormone-related Protein Is Associated with the Chaperone Protein BiP and Undergoes Proteasome-mediated Degradation Journal of Biological Chemistry. 273: 21025-21030. PMID 9694854 DOI: 10.1074/Jbc.273.33.21025  0.302
1998 Lipman ML, Panda D, Bennett HPJ, Henderson JE, Shane E, Shen Y, Goltzman D, Karaplis AC. Cloning of human PEX cDNA: Expression, subcellular localization, and endopeptidase activity Journal of Biological Chemistry. 273: 13729-13737. PMID 9593714 DOI: 10.1074/Jbc.273.22.13729  0.345
1997 Rabbani SA, Gladu J, Mazar AP, Henkin J, Goltzman D. Induction in human osteoblastic cells (SaOS2) of the early response genes fos, jun, and myc by the amino terminal fragment (ATF) of urokinase. Journal of Cellular Physiology. 172: 137-45. PMID 9258335 DOI: 10.1002/(Sici)1097-4652(199708)172:2<137::Aid-Jcp1>3.0.Co;2-P  0.361
1997 Lomri A, de Pollak C, Sebag M, Goltzman D, Kremer R, Marie PJ. Expression of parathyroid hormone-related peptide (PTHrP) and PTH/PTHrP receptor in newborn human calvaria osteoblastic cells. European Journal of Endocrinology / European Federation of Endocrine Societies. 136: 640-8. PMID 9225729 DOI: 10.1530/Eje.0.1360640  0.359
1997 Rabbani SA, Harakidas P, Gladu J, Srivastava S, Diarra A, Sauvé R, Karaplis AC, Henderson JE, Goltzman D, Hendy GN. Expression and characterization of recombinant rat parathyroid hormone-related peptide (1-141) and an amino-terminally-truncated analogue (38-141) Molecular and Cellular Endocrinology. 130: 13-21. PMID 9220017 DOI: 10.1016/S0303-7207(97)00068-3  0.318
1997 Goltzman D, Henderson JE. Parathyroid hormone-related peptide and hypercalcemia of malignancy Cancer Treatment and Research. 89: 193-215. PMID 9204194 DOI: 10.1007/978-1-4615-6355-6_10  0.39
1997 Bettoun JD, Minagawa M, Kwan MY, Lee HS, Yasuda T, Hendy GN, Goltzman D, White JH. Cloning and characterization of the promoter regions of the human parathyroid hormone (PTH)/PTH-related peptide receptor gene: analysis of deoxyribonucleic acid from normal subjects and patients with pseudohypoparathyroidism type 1b. The Journal of Clinical Endocrinology and Metabolism. 82: 1031-40. PMID 9100569 DOI: 10.1210/Jcem.82.4.3906  0.314
1997 Meerovitch K, Wing S, Goltzman D. Preproparathyroid Hormone-related Protein, a Secreted Peptide, Is a Substrate for the Ubiquitin Proteolytic System Journal of Biological Chemistry. 272: 6706-6713. PMID 9045703 DOI: 10.1074/Jbc.272.10.6706  0.327
1997 Amizuka N, Lee HS, Kwan MY, Arazani A, Warshawsky H, Hendy GN, Ozawa H, White JH, Goltzman D. Cell-specific expression of the parathyroid hormone (PTH)/PTH-related peptide receptor gene in kidney from kidney-specific and ubiquitous promoters. Endocrinology. 138: 469-81. PMID 8977437 DOI: 10.1210/Endo.138.1.4845  0.318
1996 Amizuka N, Goltzman D, Ozawa H. The Biologic Action of Parathyroid Hormone-Related Peptide on Bone and Cartilage Cells Tissue Engineering. 2: 277-287. PMID 19877959 DOI: 10.1089/Ten.1996.2.277  0.404
1996 Amizuka N, Henderson JE, Hoshi K, Warshawsky H, Ozawa H, Goltzman D, Karaplis AC. Programmed cell death of chondrocytes and aberrant chondrogenesis in mice homozygous for parathyroid hormone-related peptide gene deletion Endocrinology. 137: 5055-5067. PMID 8895380 DOI: 10.1210/Endo.137.11.8895380  0.349
1996 Henderson JE, He B, Goltzman D, Karaplis AC. Constitutive expression of parathyroid hormone-related peptide (PTHrP) stimulates growth and inhibit differentiation of CFK2 chondrocytes Journal of Cellular Physiology. 169: 33-41. PMID 8841420 DOI: 10.1002/(Sici)1097-4652(199610)169:1<33::Aid-Jcp4>3.0.Co;2-F  0.332
1996 Kremer R, Sebag M, Champigny C, Meerovitch K, Hendy GN, White J, Goltzman D. Identification and characterization of 1,25-dihydroxyvitamin D3-responsive repressor sequences in the rat parathyroid hormone-related peptide gene. Journal of Biological Chemistry. 271: 16310-16316. PMID 8663213 DOI: 10.1074/Jbc.271.27.16310  0.33
1996 Azarani A, Goltzman D, Orlowski J. Structurally diverse N-terminal peptides of parathyroid hormone (PTH) and PTH-related peptide (PTHRP) inhibit the Na+/H+ exchanger NHE3 isoform by binding to the PTH/PTHRP receptor type I and activating distinct signaling pathways. Journal of Biological Chemistry. 271: 14931-14936. PMID 8663042 DOI: 10.1074/Jbc.271.25.14931  0.338
1996 Amizuka N, Karaplis AC, Henderson JE, Warshawsky H, Lipman ML, Matsuki Y, Ejiri S, Tanaka M, Izumi N, Ozawa H, Goltzman D. Haploinsufficiency of parathyroid hormone-related peptide (PTHrP) results in abnormal postnatal bone development Developmental Biology. 175: 166-176. PMID 8608863 DOI: 10.1006/Dbio.1996.0104  0.444
1995 Azarani A, Goltzman D, Orlowski J. Parathyroid Hormone and Parathyroid Hormone-related Peptide Inhibit the Apical Na+/H+ Exchanger NHE-3 Isoform in Renal Cells (OK) via a Dual Signaling Cascade Involving Protein Kinase A and C Journal of Biological Chemistry. 270: 20004-20010. PMID 7650018 DOI: 10.1074/Jbc.270.34.20004  0.308
1995 Liu B, Amizuka N, Goltzman D, Rabbani SA. Inhibition of processing of parathyroid hormone-related peptide by anti-sense furin: effect in vitro and in vivo on rat Leydig (H-500) tumor cells. International Journal of Cancer. 63: 276-81. PMID 7591217 DOI: 10.1002/Ijc.2910630222  0.325
1995 Rabbani SA, Gladu J, Liu B, Goltzman D. Regulation in vivo of the growth of Leydig cell tumors by antisense ribonucleic acid for parathyroid hormone-related peptide. Endocrinology. 136: 5416-22. PMID 7588290 DOI: 10.1210/Endo.136.12.7588290  0.306
1995 Azarani A, Orlowski J, Goltzman D. Parathyroid Hormone and Parathyroid Hormone-related Peptide Activate the Na+/H+ Exchanger NHE-1 Isoform in Osteoblastic Cells (UMR-106) via a cAMP-dependent Pathway Journal of Biological Chemistry. 270: 23166-23172. PMID 7559463 DOI: 10.1074/Jbc.270.39.23166  0.323
1995 Liu B, Goltzman D, Rabbani SA. Processing of pro-PTHRP by the prohormone convertase, furin: effect on biological activity. The American Journal of Physiology. 268: E832-8. PMID 7539217 DOI: 10.1152/Ajpendo.1995.268.5.E832  0.302
1995 Yu J, Papavasiliou V, Rhim J, Goltzman D, Kremer R. Vitamin D analogs: new therapeutic agents for the treatment of squamous cancer and its associated hypercalcemia. Anti-Cancer Drugs. 6: 101-108. DOI: 10.1097/00001813-199502000-00012  0.329
1994 Sebag M, Henderson J, Goltzman D, Kremer R. Regulation of parathyroid hormone-related peptide production in normal human mammary epithelial cells in vitro American Journal of Physiology - Cell Physiology. 267: C723-C730. PMID 7943200 DOI: 10.1152/Ajpcell.1994.267.3.C723  0.34
1993 Haq M, Kremer R, Goltzman D, Rabbani SA. A vitamin D analogue (EB1089) inhibits parathyroid hormone-related peptide production and prevents the development of malignancy-associated hypercalcemia in vivo Journal of Clinical Investigation. 91: 2416-2422. PMID 8514854 DOI: 10.1172/Jci116475  0.317
1993 Liu B, Goltzman D, Rabbani SA. Regulation of parathyroid hormone-related peptide production in vitro by the rat hypercalcemic Leydig cell tumor H-500. Endocrinology. 132: 1658-64. PMID 8462465 DOI: 10.1210/Endo.132.4.8462465  0.351
1993 Goltzman D, Bolivar I, Rabbani SA. Studies on the pathogenesis of osteoblastic metastases by prostate cancer. Advances in Experimental Medicine and Biology. 324: 165-71. PMID 1283497 DOI: 10.1007/978-1-4615-3398-6_17  0.345
1992 Bernier SM, Goltzman D. Effect of protein and steroidal osteotropic agents on differentiation and epidermal growth factor-mediated growth of the CFK1 osseous cell line. Journal of Cellular Physiology. 152: 317-327. PMID 1639866 DOI: 10.1002/Jcp.1041520213  0.326
1992 Henderson JE, Kremer R, Rhim JS, Goltzman D. Identification and functional characterization of adenylate cyclase-linked receptors for parathyroid hormone-like peptides on immortalized human keratinocytes Endocrinology. 130: 449-457. PMID 1309343 DOI: 10.1210/Endo.130.1.1309343  0.334
1991 Bernier SM, Rouleau MF, Goltzman D. Biochemical and morphological analysis of the interaction of epidermal growth factor and parathyroid hormone with UMR 106 osteosarcoma cells. Endocrinology. 128: 2752-2760. PMID 2036959 DOI: 10.1210/Endo-128-6-2752  0.322
1991 Kremer R, Karaplis AC, Henderson J, Gulliver W, Banville D, Hendy GN, Goltzman D. Regulation of parathyroid hormone-like peptide in cultured normal human keratinocytes: Effect of growth factors and 1,25 dihydroxyvitamin D3 on gene expression and secretion Journal of Clinical Investigation. 87: 884-893. PMID 1999499 DOI: 10.1172/Jci115094  0.359
1991 Kongo T, Kupfer J, Enomoto H, Sharifi B, Giannella-Neto D, Forrester JS, Singer FR, Goltzman D, Hendy GN, Pirola C, Fagin JA, Clemens TL. Abundant expression of parathyroid hormone-related protein in primary rat aortic smooth muscle cells accompanies serum-induced proliferation Journal of Clinical Investigation. 88: 1841-1847. PMID 1752945 DOI: 10.1172/Jci115505  0.334
1991 Stern PH, Shankar G, Fargher RC, Copp DH, Milliken CE, Sato KJ, Goltzman D, Herrmann-Erlee MPM. Salmon stanniocalcin and bovine parathyroid hormone have dissimilar actions on mammalian bone Journal of Bone and Mineral Research. 6: 1153-1159. PMID 1666805 DOI: 10.1002/Jbmr.5650061103  0.417
1990 Bernier SM, Desjardins J, Sullivan AK, Goltzman D. Establishment of an osseous cell line from fetal rat calvaria using an immunocytolytic method of cell selection: characterization of the cell line and of derived clones. Journal of Cellular Physiology. 145: 274-285. PMID 2246327 DOI: 10.1002/Jcp.1041450212  0.344
1990 Asa SL, Henderson J, Goltzman D, Drucker DJ. Parathyroid hormone-like peptide in normal and neoplastic human endocrine tissues Journal of Clinical Endocrinology and Metabolism. 71: 1112-1118. PMID 2229275 DOI: 10.1210/Jcem-71-5-1112  0.302
1990 McAuley P, Asa SL, Chiu B, Henderson J, Goltzman D, Drucker DJ. Parathyroid hormone-like peptide in normal and neoplastic mesothelial cells Cancer. 66: 1975-1979. PMID 2224795 DOI: 10.1002/1097-0142(19901101)66:9<1975::Aid-Cncr2820660921>3.0.Co;2-3  0.32
1990 Rabbani SA, Kaiser SM, Henderson JE, Bernier SM, Mouland AJ, Roy DR, Zahab DM, Sung WL, Goltzman D, Hendy GN. Synthesis and characterization of extended and deleted recombinant analogues of parathyroid hormone-(1-84): correlation of peptide structure with function. Biochemistry. 29: 10080-9. PMID 2176861 DOI: 10.1021/Bi00495A010  0.328
1990 Henderson J, Bernier S, D'Amour P, Goltzman D. Effects of passive immunization against parathyroid hormone (PTH)-like peptide and PTH in hypercalcemic tumor-bearing rats and normocalcemic controls Endocrinology. 127: 1310-1318. PMID 2167215 DOI: 10.1210/Endo-127-3-1310  0.347
1990 Mitchell J, Goltzman D. Mechanisms of homologous and heterologous regulation of parathyroid hormone receptors in the rat osteosarcoma cell line UMR-106. Endocrinology. 126: 2650-2660. PMID 2158432 DOI: 10.1210/Endo-126-5-2650  0.31
1990 Mitchell J, Rouleau MF, Goltzman D. Biochemical and morphological characterization of parathyroid hormone receptor binding to the rat osteosarcoma cell line UMR-106. Endocrinology. 126: 2327-2335. PMID 2158423 DOI: 10.1210/Endo-126-5-2327  0.314
1989 Goltzman D, Hendy GN, Banville D. Parathyroid hormone-like peptide: molecular characterization and biological properties. Trends in Endocrinology and Metabolism. 1: 39-44. PMID 18411086 DOI: 10.1016/1043-2760(89)90029-5  0.327
1989 Rabbani SA, Mitchell J, Roy DR, Hendy GN, Goltzman D. Influence of the amino-terminus on in vitro and in vivo biological activity of synthetic parathyroid hormone-like peptides of malignancy. Endocrinology. 123: 2709-16. PMID 2848683 DOI: 10.1210/Endo-123-6-2709  0.341
1989 Hendy GN, Stotland MA, Grunbaum D, Fraher LJ, Loveridge N, Goltzman D. Characteristics of secondary hyperparathyroidism in vitamin D-deficient dogs. The American Journal of Physiology. 256: E765-72. PMID 2735402 DOI: 10.1152/Ajpendo.1989.256.6.E765  0.35
1989 Drucker DJ, Asa SL, Henderson J, Goltzman D. The parathyroid hormone-like peptide gene is expressed in the normal and neoplastic human endocrine pancreas Molecular Endocrinology. 3: 1589-1595. PMID 2691879 DOI: 10.1210/Mend-3-10-1589  0.32
1989 Kremer R, Bolivar I, Goltzman D, Hendy GN. Influence of Calcium and 1,25-Dihydroxycholecalciferol on Proliferation and Proto-Oncogene Expression in Primary Cultures of Bovine Parathyroid Cells* Endocrinology. 125: 935-941. PMID 2502380 DOI: 10.1210/Endo-125-2-935  0.324
1988 Rouleau MF, Mitchell J, Goltzman D. In Vivo Distribution of Parathyroid Hormone Receptors in Bone: Evidence that a Predominant Osseous Target Cell Is Not the Mature Osteoblast* Endocrinology. 123: 187-191. PMID 2838253 DOI: 10.1210/Endo-123-1-187  0.402
1988 Mitchell J, Tenenhouse A, Warner M, Goltzman D. Parathyroid hormone desensitization in renal membranes of vitamin D-deficient rats is associated with a postreceptor defect. Endocrinology. 122: 1834-1841. PMID 2834176 DOI: 10.1210/Endo-122-5-1834  0.33
1986 Rouleau MF, Warshawsky H, Goltzman D. Parathyroid Hormone Binding in Vivo to Renal, Hepatic, and Skeletal Tissues of the Rat Using a Radioautographic Approach* Endocrinology. 118: 919-931. PMID 3948781 DOI: 10.1210/Endo-118-3-919  0.325
1986 Goltzman D, Bennett HP, Koutsilieris M, Mitchell J, Rabbani SA, Rouleau MF. Studies of the multiple molecular forms of bioactive parathyroid hormone and parathyroid hormone-like substances. Recent Progress in Hormone Research. 42: 665-703. PMID 3016836 DOI: 10.1016/B978-0-12-571142-5.50020-3  0.335
1985 Mitchell J, Goltzman D. Examination of Circulating Parathyroid Hormone in Pseudohypoparathyroidism The Journal of Clinical Endocrinology and Metabolism. 61: 328-334. PMID 4008609 DOI: 10.1210/Jcem-61-2-328  0.314
1983 Reddy GS, Norman AW, Willis DM, Goltzman D, Guyda H, Solomon S, Philips DR, Bishop JE, Mayer E. Regulation of vitamin D metabolism in normal human pregnancy. The Journal of Clinical Endocrinology and Metabolism. 56: 363-70. PMID 6600459 DOI: 10.1210/Jcem-56-2-363  0.302
1982 Kremer R, Goltzman D. Parathyroid hormone stimulates mammalian renal 25-hydroxyvitamin D3-1α-hydroxylase in vitro Endocrinology. 110: 294-296. PMID 7053991 DOI: 10.1210/Endo-110-1-294  0.327
1980 Goltzman D, Henderson B, Loveridge N. Cytochemical Bioassay of Parathyroid Hormone: CHARACTERISTICS OF THE ASSAY AND ANALYSIS OF CIRCULATING HORMONAL FORMS Journal of Clinical Investigation. 65: 1309-1317. PMID 7410546 DOI: 10.1172/Jci109794  0.33
1978 Goltzman D. Examination of the requirement for metabolism of parathyroid hormone in skeletal tissue before biological action. Endocrinology. 102: 1555-1562. PMID 744038 DOI: 10.1210/Endo-102-5-1555  0.332
1978 Goltzman D, Callahan EN, Tregear GW, Potts JT. Influence of guanyl nucleotides on parathyroid hormone-stimulated adenylyl cyclase activity in renal cortical membranes Endocrinology. 103: 1352-1360. PMID 217675 DOI: 10.1210/Endo-103-4-1352  0.313
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