| Year |
Citation |
Score |
| 2023 |
Coates-Park S, Lazaroff C, Gurung S, Rich J, Colladay A, O'Neill M, Butler GS, Overall CM, Stetler-Stevenson WG, Peeney D. Tissue inhibitors of metalloproteinases are proteolytic targets of matrix metalloproteinase 9. Matrix Biology : Journal of the International Society For Matrix Biology. 123: 59-70. PMID 37804930 DOI: 10.1016/j.matbio.2023.09.002 |
0.442 |
|
| 2022 |
Haack AM, Overall CM, Keller UAD. Degradomics technologies in matrisome exploration. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 36280126 DOI: 10.1016/j.matbio.2022.10.003 |
0.317 |
|
| 2020 |
Omenn GS, Lane L, Overall CM, Cristea IM, Corrales FJ, Lindskog C, Paik YK, Van Eyk JE, Liu S, Pennington S, Snyder MP, Baker MS, Bandeira N, Aebersold R, Moritz RL, et al. Research on The Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, according to the HUPO Human Proteome Project. Journal of Proteome Research. PMID 32931287 DOI: 10.1021/Acs.Jproteome.0C00485 |
0.344 |
|
| 2020 |
Falkowski K, Bielecka E, Thøgersen IB, Bocheńska O, Płaza K, Kalińska M, Sąsiadek L, Magoch M, Pęcak A, Wiśniewska M, Gruba N, Wysocka M, Wojtysiak A, Brzezińska-Bodal M, Sychowska K, ... ... Overall CM, et al. Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis. International Journal of Molecular Sciences. 21. PMID 32575583 DOI: 10.3390/Ijms21124383 |
0.523 |
|
| 2019 |
Fallata AM, Wyatt RA, Levesque JM, Dufour A, Overall CM, Crawford BD. Intracellular Localization in Zebrafish Muscle and Conserved Sequence Features Suggest Roles for Gelatinase A Moonlighting in Sarcomere Maintenance. Biomedicines. 7. PMID 31795436 DOI: 10.3390/Biomedicines7040093 |
0.425 |
|
| 2019 |
Jobin PG, Solis N, Machado Y, Bell PA, Rai SK, Kwon NH, Kim S, Overall CM, Butler GS. Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage. The Journal of Biological Chemistry. PMID 31771979 DOI: 10.1074/Jbc.Ra119.010486 |
0.516 |
|
| 2019 |
Bell PA, Solis N, Kizhakkedathu J, Matthew I, Overall CM. Proteomic and N-terminomic TAILS analyses of human alveolar bone proteins: Improved protein extraction methodology and LysargiNase digestion strategies increase proteome coverage and missing protein identification. Journal of Proteome Research. PMID 31601107 DOI: 10.1021/Acs.Jproteome.9B00445 |
0.373 |
|
| 2019 |
Omenn GS, Lane L, Overall CM, Corrales FJ, Schwenk JM, Paik YK, Van Eyk JE, Liu S, Pennington S, Snyder MP, Baker MS, Deutsch EW. Progress on Identifying and Characterizing the Human Proteome: 2018-2019 Metrics from the HUPO Human Proteome Project. Journal of Proteome Research. PMID 31430157 DOI: 10.1021/Acs.Jproteome.9B00434 |
0.347 |
|
| 2019 |
Zelanis A, Oliveira AK, Prudova A, Huesgen PF, Tashima AK, Kizhakkedathu J, Overall CM, de Toledo Serrano SM. Deep profiling of the cleavage specificity and human substrates of snake venom metalloprotease HF3 by PICS using proteome derived peptide libraries and TAILS N-terminomics. Journal of Proteome Research. PMID 31337208 DOI: 10.1021/Acs.Jproteome.9B00325 |
0.467 |
|
| 2019 |
Jobin PG, Solis N, Machado Y, Bell PA, Kwon NH, Kim S, Overall CM, Butler GS. Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase. The Journal of Biological Chemistry. PMID 31324718 DOI: 10.1074/Jbc.Ra119.009584 |
0.506 |
|
| 2019 |
Lee J, Vinh N, Drinkwater N, Yang W, Kannan Sivaraman K, Schembri LS, Gazdik M, Grin P, Butler G, Overall CM, Charman SA, McGowan S, Scammells PJ. Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions. Journal of Medicinal Chemistry. PMID 31251594 DOI: 10.1021/Acs.Jmedchem.9B00757 |
0.342 |
|
| 2019 |
Chopra S, Overall CM, Dufour A. Matrix metalloproteinases in the CNS: interferons get nervous. Cellular and Molecular Life Sciences : Cmls. PMID 31165203 DOI: 10.1007/S00018-019-03171-9 |
0.5 |
|
| 2019 |
Ehrhardt K, Steck N, Kappelhoff R, Stein S, Rieder F, Gordon IO, Boyle EC, Braubach P, Overall CM, Finlay BB, Grassl GA. Persistent Salmonella enterica Serovar Typhimurium Infection Induces Protease Expression During Intestinal Fibrosis. Inflammatory Bowel Diseases. PMID 31066456 DOI: 10.1093/Ibd/Izz070 |
0.334 |
|
| 2019 |
Quancard J, Klein T, Fung SY, Renatus M, Hughes N, Israël L, Priatel JJ, Kang S, Blank MA, Viner RI, Blank J, Schlapbach A, Erbel P, Kizhakkedathu J, Villard F, ... ... Overall CM, et al. An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient. Nature Chemical Biology. PMID 30692685 DOI: 10.1038/S41589-018-0222-1 |
0.37 |
|
| 2018 |
Paik YK, Overall CM, Corrales F, Deutsch EW, Lane L, Omenn GS. Toward Completion of the Human Proteome Parts List: Progress Uncovering Proteins That Are Missing or Have Unknown Function and Developing Analytical Methods. Journal of Proteome Research. 17: 4023-4030. PMID 30985145 DOI: 10.1021/Acs.Jproteome.8B00885 |
0.312 |
|
| 2018 |
Marshall NC, Klein T, Thejoe M, von Krosigk N, Kizhakkedathu J, Finlay BB, Overall CM. Global Profiling of Proteolysis from the Mitochondrial Amino Terminome during Early Intrinsic Apoptosis Prior to Caspase-3 Activation. Journal of Proteome Research. PMID 30371095 DOI: 10.1021/Acs.Jproteome.8B00675 |
0.304 |
|
| 2018 |
Mallia-Milanes B, Dufour A, Philp C, Solis N, Klein T, Fischer M, Bolton CE, Shapiro SD, Overall CM, Johnson SR. TAILS proteomics reveals dynamic changes in airway proteolysis controlling protease activity and innate immunity during COPD exacerbations. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30284925 DOI: 10.1152/Ajplung.00175.2018 |
0.426 |
|
| 2018 |
Paik YK, Lane L, Kawamura T, Chen YJ, Cho JY, LaBaer J, Yoo JS, Domont GB, Corrales F, Omenn GS, Archakov A, Encarnación-Guevara S, Liu S, Salekdeh GH, Cho JY, ... ... Overall CM, et al. Launching the C-HPP pilot project for functional characterization of identified proteins with no known function. Journal of Proteome Research. PMID 30269496 DOI: 10.1021/Acs.Jproteome.8B00383 |
0.345 |
|
| 2018 |
Omenn GS, Lane L, Overall CM, Corrales FJ, Schwenk JM, Paik YK, Van Eyk JE, Liu S, Snyder M, Baker MS, Deutsch EW. Progress on Identifying and Characterizing the Human Proteome: 2018 Metrics from the HUPO Human Proteome Project. Journal of Proteome Research. PMID 30099871 DOI: 10.1021/Acs.Jproteome.8B00441 |
0.346 |
|
| 2018 |
Russo V, Klein T, Lim DJ, Solis N, Machado Y, Hiroyasu S, Nabai L, Shen Y, Zeglinski MR, Zhao H, Oram CP, Lennox PA, Van Laeken N, Carr NJ, Crawford RI, ... ... Overall CM, et al. Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction. Scientific Reports. 8: 9690. PMID 29946113 DOI: 10.1038/S41598-018-28070-0 |
0.348 |
|
| 2018 |
Dufour A, Bellac CL, Eckhard U, Solis N, Klein T, Kappelhoff R, Fortelny N, Jobin P, Rozmus J, Mark J, Pavlidis P, Dive V, Barbour SJ, Overall CM. C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease. Nature Communications. 9: 2416. PMID 29925830 DOI: 10.1038/S41467-018-04717-4 |
0.425 |
|
| 2018 |
Tharmarajah G, Eckhard U, Jain F, Marino G, Prudova A, Urtatiz O, Fuchs H, Hrabe de Angelis M, Overall CM, Van Raamsdonk CD. Melanocyte development in the mouse tail epidermis requires the Adamts9 metalloproteinase. Pigment Cell & Melanoma Research. PMID 29781574 DOI: 10.1111/Pcmr.12711 |
0.338 |
|
| 2018 |
King SL, Goth CK, Eckhard U, Joshi HJ, Haue AD, Vakhrushev S, Schjoldager K, Overall CM, Wandall HH. TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation. The Journal of Biological Chemistry. PMID 29593093 DOI: 10.1074/Jbc.Ra118.001978 |
0.404 |
|
| 2018 |
Jagdeo JM, Dufour A, Klein T, Solis N, Kleifeld O, Kizhakkedathu J, Luo H, Overall CM, Jan E. N-Terminomics TAILS identifies host cell substrates of poliovirus and coxsackievirus B3 3C proteinases that modulate virus infection. Journal of Virology. PMID 29437971 DOI: 10.1128/Jvi.02211-17 |
0.326 |
|
| 2018 |
Solis N, Overall CM. Identification of Protease Cleavage Sites and Substrates in Cancer by Carboxy-TAILS (C-TAILS). Methods in Molecular Biology (Clifton, N.J.). 1731: 15-28. PMID 29318539 DOI: 10.1007/978-1-4939-7595-2_2 |
0.345 |
|
| 2017 |
Klein T, Eckhard U, Dufour A, Solis N, Overall CM. Proteolytic Cleavage-Mechanisms, Function, and "Omic" Approaches for a Near-Ubiquitous Posttranslational Modification. Chemical Reviews. PMID 29265812 DOI: 10.1021/Acs.Chemrev.7B00120 |
0.392 |
|
| 2017 |
Paik YK, Overall CM, Deutsch EW, Van Eyk JE, Omenn GS. Progress and Future Direction of Chromosome-Centric Human Proteome Project. Journal of Proteome Research. 16: 4253-4258. PMID 29191025 DOI: 10.1021/Acs.Jproteome.7B00734 |
0.311 |
|
| 2017 |
Na CH, Barbhuiya M, Kim MS, Verbruggen S, Eacker S, Pletnikova O, Troncoso J, Halushka M, Menschaert G, Overall C, Pandey A. Discovery of non-canonical translation initiation sites through mass spectrometric analysis of protein N-termini. Genome Research. PMID 29162641 DOI: 10.1101/Gr.226050.117 |
0.337 |
|
| 2017 |
Paik YK, Omenn GS, Lane L, Overall CM. Advances in the Chromosome-Centric Human Proteome Project: Looking to the Future. Expert Review of Proteomics. PMID 29039980 DOI: 10.1080/14789450.2017.1394189 |
0.318 |
|
| 2017 |
Abbey SR, Eckhard U, Solis N, Marino G, Matthew I, Overall CM. The Human Odontoblast Cell Layer and Dental Pulp Proteomes and N-Terminomes. Journal of Dental Research. 22034517736054. PMID 29035686 DOI: 10.1177/0022034517736054 |
0.348 |
|
| 2017 |
Schwenk JM, Omenn GS, Sun Z, Campbell DS, Baker MS, Overall CM, Aebersold R, Moritz RL, Deutsch EW. The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays. Journal of Proteome Research. PMID 28938075 DOI: 10.1021/Acs.Jproteome.7B00467 |
0.307 |
|
| 2017 |
Eckhard U, Bandukwala H, Mansfield MJ, Marino G, Cheng J, Wallace I, Holyoak T, Charles TC, Austin J, Overall CM, Doxey AC. Discovery of a proteolytic flagellin family in diverse bacterial phyla that assembles enzymatically active flagella. Nature Communications. 8: 521. PMID 28900095 DOI: 10.1038/S41467-017-00599-0 |
0.349 |
|
| 2017 |
Omenn GS, Lane L, Lundberg EK, Overall CM, Deutsch EW. Progress on the HUPO Draft Human Proteome: 2017 Metrics of the Human Proteome Project. Journal of Proteome Research. PMID 28853897 DOI: 10.1021/Acs.Jproteome.7B00375 |
0.336 |
|
| 2017 |
Kappelhoff R, Puente XS, Wilson CH, Seth A, Lopez-Otin C, Overall CM. Overview of transcriptomic analysis of all human proteases, non-proteolytic homologs and inhibitors: Organ, tissue and ovarian cancer cell line expression profiling of the human protease degradome by the CLIP-CHIP™ DNA microarray. Biochimica Et Biophysica Acta. PMID 28797648 DOI: 10.1016/J.Bbamcr.2017.08.004 |
0.341 |
|
| 2017 |
Panwar P, Butler GS, Jamroz A, Azizi P, Overall CM, Brömme D. Aging-associated modifications of collagen affect its degradation by matrix metalloproteinases. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28634008 DOI: 10.1016/J.Matbio.2017.06.004 |
0.454 |
|
| 2017 |
Jobin PG, Butler GS, Overall CM. New intracellular activities of matrix metalloproteinases shine in the moonlight. Biochimica Et Biophysica Acta. PMID 28526562 DOI: 10.1016/J.Bbamcr.2017.05.013 |
0.526 |
|
| 2017 |
Fortelny N, Butler GS, Overall CM, Pavlidis P. Protease-inhibitor interaction predictions: Lessons on the complexity of protein-protein interactions. Molecular & Cellular Proteomics : McP. PMID 28385878 DOI: 10.1074/Mcp.M116.065706 |
0.317 |
|
| 2017 |
Poreba M, Szalek A, Rut W, Kasperkiewicz P, Rutkowska-Wlodarczyk I, Snipas SJ, Itoh Y, Turk D, Turk B, Overall CM, Kaczmarek L, Salvesen GS, Drag M. Highly sensitive and adaptable fluorescence-quenched pair discloses the substrate specificity profiles in diverse protease families. Scientific Reports. 7: 43135. PMID 28230157 DOI: 10.1038/Srep43135 |
0.399 |
|
| 2017 |
Taggart C, Mall MA, Lalmanach G, Cataldo D, Ludwig A, Janciauskiene S, Heath N, Meiners S, Overall CM, Schultz C, Turk B, Borensztajn KS. Protean proteases: at the cutting edge of lung diseases. The European Respiratory Journal. 49. PMID 28179435 DOI: 10.1183/13993003.01200-2015 |
0.416 |
|
| 2017 |
Marshall NC, Finlay BB, Overall CM. Sharpening host defenses during infection: Proteases cut to the chase. Molecular & Cellular Proteomics : McP. PMID 28179412 DOI: 10.1074/Mcp.O116.066456 |
0.328 |
|
| 2017 |
Scott NE, Rogers LD, Prudova A, Brown NF, Fortelny N, Overall CM, Foster LJ. Interactome disassembly during apoptosis occurs independent of caspase cleavage. Molecular Systems Biology. 13: 906. PMID 28082348 DOI: 10.15252/Msb.20167067 |
0.306 |
|
| 2016 |
Klein T, Viner RI, Overall CM. Quantitative proteomics and terminomics to elucidate the role of ubiquitination and proteolysis in adaptive immunity. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 374. PMID 27644975 DOI: 10.1098/Rsta.2015.0372 |
0.304 |
|
| 2016 |
Abdul-Muneer PM, Conte AA, Haldar D, Long M, Patel R, Santhakumar V, Overall CM, Pfister BJ. Traumatic brain injury induced matrix metalloproteinase2 cleaves CXCL12α (stromal cell derived factor 1α) and causes neurodegeneration. Brain, Behavior, and Immunity. PMID 27614125 DOI: 10.1016/J.Bbi.2016.09.002 |
0.425 |
|
| 2016 |
Qing X, Rogers L, Mortha A, Lavin Y, Redecha P, Issuree PD, Maretzky T, Merad M, McIlwain D, Mak TW, Overall CM, Blobel CP, Salmon JE. iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice. European Journal of Immunology. PMID 27601030 DOI: 10.1002/Eji.201646482 |
0.313 |
|
| 2016 |
Omenn GS, Lane L, Lundberg EK, Beavis RC, Overall CM, Deutsch EW. Metrics for the Human Proteome Project 2016: Progress on Identifying and Characterizing the Human Proteome, Including Post-Translational Modifications. Journal of Proteome Research. PMID 27487407 DOI: 10.1021/Acs.Jproteome.6B00511 |
0.353 |
|
| 2016 |
Prudova A, Gocheva V, Auf dem Keller U, Eckhard U, Olson OC, Akkari L, Butler GS, Fortelny N, Lange PF, Mark JC, Joyce JA, Overall CM. TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors. Cell Reports. PMID 27477282 DOI: 10.1016/J.Celrep.2016.06.086 |
0.688 |
|
| 2016 |
Butler GS, Connor AR, Sounni NE, Eckhard U, Morrison CJ, Noël A, Overall CM. Degradomic and yeast 2-hybrid inactive catalytic domain substrate trapping identifies new membrane-type 1 matrix metalloproteinase (MMP14) substrates: CCN3 (Nov) and CCN5 (WISP2). Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27471094 DOI: 10.1016/J.Matbio.2016.07.006 |
0.521 |
|
| 2016 |
Moon H, Cremmel CV, Kulpa A, Jaeger NA, Kappelhoff R, Overall CM, Waterfield JD, Brunette DM. Novel Grooved Substrata Stimulate Macrophage Fusion, CCL2 and MMP-9 Secretion. Journal of Biomedical Materials Research. Part A. PMID 27102570 DOI: 10.1002/Jbm.A.35757 |
0.318 |
|
| 2016 |
Eckhard U, Huesgen PF, Schilling O, Bellac CL, Butler GS, Cox JH, Dufour A, Goebeler V, Kappelhoff R, Auf dem Keller U, Klein T, Lange PF, Marino G, Morrison CJ, Prudova A, ... ... Overall CM, et al. Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14. Data in Brief. 7: 299-310. PMID 26981551 DOI: 10.1016/J.Dib.2016.02.036 |
0.724 |
|
| 2016 |
Eckhard U, Marino G, Butler GS, Overall CM. Positional proteomics in the era of the human proteome project on the doorstep of precision medicine. Biochimie. 122: 110-8. PMID 26542287 DOI: 10.1016/J.Biochi.2015.10.018 |
0.403 |
|
| 2016 |
Tam V, Solis N, Overall C, Klein T, Cheung KMC, Cheah KSE, Chan D. Degradome of the Interverteral Disc Global Spine Journal. 6: s-0036-1582633-s-003. DOI: 10.1055/S-0036-1582633 |
0.435 |
|
| 2015 |
Hamey JJ, Winter DL, Yagoub D, Overall CM, Hart-Smith G, Wilkins MR. Novel N-terminal and lysine methyltransferases that target translation elongation factor 1A in yeast and human. Molecular & Cellular Proteomics : McP. PMID 26545399 DOI: 10.1074/Mcp.M115.052449 |
0.305 |
|
| 2015 |
Klein T, Fung SY, Renner F, Blank MA, Dufour A, Kang S, Bolger-Munro M, Scurll JM, Priatel JJ, Schweigler P, Melkko S, Gold MR, Viner RI, Régnier CH, Turvey SE, ... Overall CM, et al. The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling. Nature Communications. 6: 8777. PMID 26525107 DOI: 10.1038/Ncomms9777 |
0.318 |
|
| 2015 |
Eckhard U, Huesgen PF, Schilling O, Bellac CL, Butler GS, Cox JH, Dufour A, Goebeler V, Kappelhoff R, Keller UA, Klein T, Lange PF, Marino G, Morrison CJ, Prudova A, ... ... Overall CM, et al. Active site specificity of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 26407638 DOI: 10.1016/J.Matbio.2015.09.003 |
0.734 |
|
| 2015 |
Eckhard U, Marino G, Abbey SR, Tharmarajah G, Matthew I, Overall CM. The Human Dental Pulp Proteome and N-Terminome: Levering the Unexplored Potential of Semitryptic Peptides Enriched by TAILS to Identify Missing Proteins in the Human Proteome Project in Underexplored Tissues. Journal of Proteome Research. 14: 3568-82. PMID 26258467 DOI: 10.1021/Acs.Jproteome.5B00579 |
0.4 |
|
| 2015 |
Marino G, Eckhard U, Overall CM. Protein Termini and Their Modifications Revealed by Positional Proteomics. Acs Chemical Biology. 10: 1754-64. PMID 26042555 DOI: 10.1021/Acschembio.5B00189 |
0.365 |
|
| 2015 |
Fortelny N, Pavlidis P, Overall CM. The path of no return-Truncated protein N-termini and current ignorance of their genesis. Proteomics. 15: 2547-52. PMID 26010509 DOI: 10.1002/Pmic.201500043 |
0.349 |
|
| 2015 |
Repnik U, Starr AE, Overall CM, Turk B. Cysteine Cathepsins Activate ELR Chemokines and Inactivate Non-ELR Chemokines. The Journal of Biological Chemistry. 290: 13800-11. PMID 25833952 DOI: 10.1074/Jbc.M115.638395 |
0.407 |
|
| 2015 |
Zelanis A, Huesgen PF, Oliveira AK, Tashima AK, Serrano SM, Overall CM. Snake venom serine proteinases specificity mapping by proteomic identification of cleavage sites. Journal of Proteomics. 113: 260-7. PMID 25452133 DOI: 10.1016/J.Jprot.2014.10.002 |
0.351 |
|
| 2015 |
Huesgen PF, Lange PF, Rogers LD, Solis N, Eckhard U, Kleifeld O, Goulas T, Gomis-Rüth FX, Overall CM. LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification Nature Methods. 12: 55-58. PMID 25419962 DOI: 10.1038/Nmeth.3177 |
0.667 |
|
| 2015 |
Fortelny N, Yang S, Pavlidis P, Lange PF, Overall CM. Proteome TopFIND 3.0 with TopFINDer and PathFINDer: database and analysis tools for the association of protein termini to pre- and post-translational events. Nucleic Acids Research. 43: D290-7. PMID 25332401 DOI: 10.1093/Nar/Gku1012 |
0.687 |
|
| 2015 |
Delolme F, Anastasi C, Alcaraz LB, Mendoza V, Vadon-Le Goff S, Talantikite M, Capomaccio R, Mevaere J, Fortin L, Mazzocut D, Damour O, Zanella-Cléon I, Hulmes DJ, Overall CM, Valcourt U, et al. Proteolytic control of TGF-β co-receptor activity by BMP-1/tolloid-like proteases revealed by quantitative iTRAQ proteomics. Cellular and Molecular Life Sciences : Cmls. 72: 1009-27. PMID 25260970 DOI: 10.1007/S00018-014-1733-X |
0.361 |
|
| 2015 |
Mallia-Milanes B, Dufour A, Bailey H, Meakin G, Leme A, Bolton C, Shapiro S, Overall C, Johnson S. S129 A two species proteomics approach to determine MMP-12 substrates in COPD Thorax. 70: A73.2-A74. DOI: 10.1136/Thoraxjnl-2015-207770.135 |
0.502 |
|
| 2014 |
Prudova A, Serrano K, Eckhard U, Fortelny N, Devine DV, Overall CM. TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage. Blood. 124: e49-60. PMID 25331112 DOI: 10.1182/Blood-2014-04-569640 |
0.4 |
|
| 2014 |
Bellac CL, Dufour A, Krisinger MJ, Loonchanta A, Starr AE, Auf dem Keller U, Lange PF, Goebeler V, Kappelhoff R, Butler GS, Burtnick LD, Conway EM, Roberts CR, Overall CM. Macrophage matrix metalloproteinase-12 dampens inflammation and neutrophil influx in arthritis. Cell Reports. 9: 618-32. PMID 25310974 DOI: 10.1016/J.Celrep.2014.09.006 |
0.74 |
|
| 2014 |
Barré O, Dufour A, Eckhard U, Kappelhoff R, Béliveau F, Leduc R, Overall CM. Cleavage specificity analysis of six type II transmembrane serine proteases (TTSPs) using PICS with proteome-derived peptide libraries Plos One. 9. PMID 25211023 DOI: 10.1371/Journal.Pone.0105984 |
0.368 |
|
| 2014 |
Cruz R, Huesgen P, Riley SP, Wlodawer A, Faro C, Overall CM, Martinez JJ, Simões I. RC1339/APRc from Rickettsia conorii is a novel aspartic protease with properties of retropepsin-like enzymes. Plos Pathogens. 10: e1004324. PMID 25144529 DOI: 10.1371/Journal.Ppat.1004324 |
0.359 |
|
| 2014 |
Fortelny N, Cox JH, Kappelhoff R, Starr AE, Lange PF, Pavlidis P, Overall CM. Network analyses reveal pervasive functional regulation between proteases in the human protease web. Plos Biology. 12: e1001869. PMID 24865846 DOI: 10.1371/Journal.Pbio.1001869 |
0.731 |
|
| 2014 |
Marchant DJ, Bellac CL, Moraes TJ, Wadsworth SJ, Dufour A, Butler GS, Bilawchuk LM, Hendry RG, Robertson AG, Cheung CT, Ng J, Ang L, Luo Z, Heilbron K, Norris MJ, ... ... Overall CM, et al. A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity. Nature Medicine. 20: 493-502. PMID 24784232 DOI: 10.1038/Nm.3508 |
0.442 |
|
| 2014 |
Lange PF, Huesgen PF, Nguyen K, Overall CM. Annotating N termini for the human proteome project: N termini and Nα-acetylation status differentiate stable cleaved protein species from degradation remnants in the human erythrocyte proteome. Journal of Proteome Research. 13: 2028-44. PMID 24555563 DOI: 10.1021/Pr401191W |
0.684 |
|
| 2014 |
Huesgen PF, Lange PF, Overall CM. Ensembles of protein termini and specific proteolytic signatures as candidate biomarkers of disease. Proteomics. Clinical Applications. 8: 338-50. PMID 24497460 DOI: 10.1002/Prca.201300104 |
0.675 |
|
| 2014 |
Marino G, Huesgen PF, Eckhard U, Overall CM, Schröder WP, Funk C. Family-wide characterization of matrix metalloproteinases from Arabidopsis thaliana reveals their distinct proteolytic activity and cleavage site specificity. The Biochemical Journal. 457: 335-46. PMID 24156403 DOI: 10.1042/Bj20130196 |
0.53 |
|
| 2014 |
Eckhard U, Huesgen PF, Brandstetter H, Overall CM. Proteomic protease specificity profiling of clostridial collagenases reveals their intrinsic nature as dedicated degraders of collagen. Journal of Proteomics. 100: 102-14. PMID 24125730 DOI: 10.1016/J.Jprot.2013.10.004 |
0.411 |
|
| 2014 |
Fahlman RP, Chen W, Overall CM. Absolute proteomic quantification of the activity state of proteases and proteolytic cleavages using proteolytic signature peptides and isobaric tags. Journal of Proteomics. 100: 79-91. PMID 24060996 DOI: 10.1016/J.Jprot.2013.09.006 |
0.412 |
|
| 2013 |
Huesgen PF, Alami M, Lange PF, Foster LJ, Schröder WP, Overall CM, Green BR. Proteomic amino-termini profiling reveals targeting information for protein import into complex plastids. Plos One. 8: e74483. PMID 24066144 DOI: 10.1371/Journal.Pone.0074483 |
0.671 |
|
| 2013 |
Broder C, Arnold P, Goff SVL, Konerding MA, Bahr K, Müller S, Overall CM, Bond JS, Koudelka T, Tholey A, Hulmes DJS, Moali C, Becker-Pauly C. Metalloproteases meprin α and meprin β are C- and N-procollagen proteinases important for collagen assembly and tensile strength Proceedings of the National Academy of Sciences of the United States of America. 110: 14219-14224. PMID 23940311 DOI: 10.1073/Pnas.1305464110 |
0.326 |
|
| 2013 |
Butler GS, Overall CM. Matrix metalloproteinase processing of signaling molecules to regulate inflammation. Periodontology 2000. 63: 123-48. PMID 23931058 DOI: 10.1111/Prd.12035 |
0.461 |
|
| 2013 |
Solomonson M, Huesgen PF, Wasney GA, Watanabe N, Gruninger RJ, Prehna G, Overall CM, Strynadka NC. Structure of the mycosin-1 protease from the mycobacterial ESX-1 protein type VII secretion system. The Journal of Biological Chemistry. 288: 17782-90. PMID 23620593 DOI: 10.1074/Jbc.M113.462036 |
0.395 |
|
| 2013 |
Dufour A, Overall CM. Missing the target: matrix metalloproteinase antitargets in inflammation and cancer. Trends in Pharmacological Sciences. 34: 233-42. PMID 23541335 DOI: 10.1016/J.Tips.2013.02.004 |
0.503 |
|
| 2013 |
Wilson CH, Indarto D, Doucet A, Pogson LD, Pitman MR, McNicholas K, Menz RI, Overall CM, Abbott CA. Identifying natural substrates for dipeptidyl peptidases 8 and 9 using terminal amine isotopic labeling of substrates (TAILS) reveals in vivo roles in cellular homeostasis and energy metabolism. The Journal of Biological Chemistry. 288: 13936-49. PMID 23519473 DOI: 10.1074/Jbc.M112.445841 |
0.342 |
|
| 2013 |
auf dem Keller U, Prudova A, Eckhard U, Fingleton B, Overall CM. Systems-level analysis of proteolytic events in increased vascular permeability and complement activation in skin inflammation. Science Signaling. 6: rs2. PMID 23322905 DOI: 10.1126/Scisignal.2003512 |
0.458 |
|
| 2013 |
Lange PF, Overall CM. Protein TAILS: when termini tell tales of proteolysis and function. Current Opinion in Chemical Biology. 17: 73-82. PMID 23298954 DOI: 10.1016/J.Cbpa.2012.11.025 |
0.685 |
|
| 2013 |
Korpos É, Kadri N, Kappelhoff R, Wegner J, Overall CM, Weber E, Holmberg D, Cardell S, Sorokin L. The peri-islet basement membrane, a barrier to infiltrating leukocytes in type 1 diabetes in mouse and human. Diabetes. 62: 531-42. PMID 23139348 DOI: 10.2337/Db12-0432 |
0.341 |
|
| 2013 |
Jefferson T, Auf Dem Keller U, Bellac C, Metz VV, Broder C, Hedrich J, Ohler A, Maier W, Magdolen V, Sterchi E, Bond JS, Jayakumar A, Traupe H, Chalaris A, Rose-John S, ... ... Overall CM, et al. The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10 Cellular and Molecular Life Sciences. 70: 309-333. PMID 22940918 DOI: 10.1007/S00018-012-1106-2 |
0.434 |
|
| 2013 |
Tester AM, Cox JH, Connor AR, Starr AE, Dean RA, Puente XS, López-Otín C, Overall CM. Enhanced bioactivity of MMP-truncated CXCL8 in vitro and in vivo. Plos One. DOI: 10.1371/Journal.Pone.0000312.G007 |
0.479 |
|
| 2012 |
auf dem Keller U, Overall CM. CLIPPER: an add-on to the Trans-Proteomic Pipeline for the automated analysis of TAILS N-terminomics data. Biological Chemistry. 393: 1477-83. PMID 23667905 DOI: 10.1515/Hsz-2012-0269 |
0.326 |
|
| 2012 |
Patel TR, Butler G, McFarlane A, Xie I, Overall CM, Stetefeld J. Site specific cleavage mediated by MMPs regulates function of agrin. Plos One. 7: e43669. PMID 22984437 DOI: 10.1371/Journal.Pone.0043669 |
0.473 |
|
| 2012 |
Starr AE, Bellac CL, Dufour A, Goebeler V, Overall CM. Biochemical characterization and N-terminomics analysis of leukolysin, the membrane-type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophage phagocytic activities. The Journal of Biological Chemistry. 287: 13382-95. PMID 22367194 DOI: 10.1074/Jbc.M111.314179 |
0.559 |
|
| 2012 |
Starr AE, Dufour A, Maier J, Overall CM. Biochemical analysis of matrix metalloproteinase activation of chemokines CCL15 and CCL23 and increased glycosaminoglycan binding of CCL16. The Journal of Biological Chemistry. 287: 5848-60. PMID 22147696 DOI: 10.1074/Jbc.M111.314609 |
0.508 |
|
| 2012 |
Lange PF, Huesgen PF, Overall CM. TopFIND 2.0--linking protein termini with proteolytic processing and modifications altering protein function. Nucleic Acids Research. 40: D351-61. PMID 22102574 DOI: 10.1093/Nar/Gkr1025 |
0.688 |
|
| 2012 |
Huesgen PF, Overall CM. N- and C-terminal degradomics: new approaches to reveal biological roles for plant proteases from substrate identification. Physiologia Plantarum. 145: 5-17. PMID 22023699 DOI: 10.1111/J.1399-3054.2011.01536.X |
0.416 |
|
| 2011 |
Doucet A, Overall CM. Amino-Terminal Oriented Mass Spectrometry of Substrates (ATOMS) N-terminal sequencing of proteins and proteolytic cleavage sites by quantitative mass spectrometry. Methods in Enzymology. 501: 275-93. PMID 22078539 DOI: 10.1016/B978-0-12-385950-1.00013-4 |
0.41 |
|
| 2011 |
Kleifeld O, Doucet A, Prudova A, auf dem Keller U, Gioia M, Kizhakkedathu JN, Overall CM. Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates. Nature Protocols. 6: 1578-611. PMID 21959240 DOI: 10.1038/Nprot.2011.382 |
0.358 |
|
| 2011 |
Schilling O, Huesgen PF, Barré O, Overall CM. Identification and relative quantification of native and proteolytically generated protein C-termini from complex proteomes: C-terminome analysis. Methods in Molecular Biology (Clifton, N.J.). 781: 59-69. PMID 21877277 DOI: 10.1007/978-1-61779-276-2_4 |
0.332 |
|
| 2011 |
Schilling O, auf dem Keller U, Overall CM. Factor Xa subsite mapping by proteome-derived peptide libraries improved using WebPICS, a resource for proteomic identification of cleavage sites. Biological Chemistry. 392: 1031-7. PMID 21846260 DOI: 10.1515/Bc.2011.158 |
0.322 |
|
| 2011 |
Lange PF, Overall CM. TopFIND, a knowledgebase linking protein termini with function. Nature Methods. 8: 703-4. PMID 21822272 DOI: 10.1038/Nmeth.1669 |
0.653 |
|
| 2011 |
Morrison C, Mancini S, Cipollone J, Kappelhoff R, Roskelley C, Overall C. Microarray and proteomic analysis of breast cancer cell and osteoblast co-cultures: role of osteoblast matrix metalloproteinase (MMP)-13 in bone metastasis. The Journal of Biological Chemistry. 286: 34271-85. PMID 21784845 DOI: 10.1074/Jbc.M111.222513 |
0.418 |
|
| 2011 |
Ferraro GB, Morrison CJ, Overall CM, Strittmatter SM, Fournier AE. Membrane-type matrix metalloproteinase-3 regulates neuronal responsiveness to myelin through Nogo-66 receptor 1 cleavage. The Journal of Biological Chemistry. 286: 31418-24. PMID 21768085 DOI: 10.1074/Jbc.M111.249169 |
0.368 |
|
| 2011 |
Becker-Pauly C, Barré O, Schilling O, Auf dem Keller U, Ohler A, Broder C, Schütte A, Kappelhoff R, Stöcker W, Overall CM. Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substrates. Molecular & Cellular Proteomics : McP. 10: M111.009233. PMID 21693781 DOI: 10.1074/Mcp.M111.009233 |
0.38 |
|
| 2011 |
Jefferson T, Čaušević M, auf dem Keller U, Schilling O, Isbert S, Geyer R, Maier W, Tschickardt S, Jumpertz T, Weggen S, Bond JS, Overall CM, Pietrzik CU, Becker-Pauly C. Metalloprotease meprin beta generates nontoxic N-terminal amyloid precursor protein fragments in vivo. The Journal of Biological Chemistry. 286: 27741-50. PMID 21646356 DOI: 10.1074/Jbc.M111.252718 |
0.387 |
|
| 2011 |
Doucet A, Kleifeld O, Kizhakkedathu JN, Overall CM. Identification of proteolytic products and natural protein N-termini by Terminal Amine Isotopic Labeling of Substrates (TAILS). Methods in Molecular Biology (Clifton, N.J.). 753: 273-87. PMID 21604129 DOI: 10.1007/978-1-61779-148-2_18 |
0.349 |
|
| 2011 |
Schilling O, auf dem Keller U, Overall CM. Protease specificity profiling by tandem mass spectrometry using proteome-derived peptide libraries. Methods in Molecular Biology (Clifton, N.J.). 753: 257-72. PMID 21604128 DOI: 10.1007/978-1-61779-148-2_17 |
0.339 |
|
| 2011 |
Schilling O, Huesgen PF, Barré O, Auf dem Keller U, Overall CM. Characterization of the prime and non-prime active site specificities of proteases by proteome-derived peptide libraries and tandem mass spectrometry. Nature Protocols. 6: 111-20. PMID 21212787 DOI: 10.1038/Nprot.2010.178 |
0.361 |
|
| 2011 |
Doucet A, Overall CM. Broad coverage identification of multiple proteolytic cleavage site sequences in complex high molecular weight proteins using quantitative proteomics as a complement to edman sequencing. Molecular & Cellular Proteomics : McP. 10: M110.003533. PMID 20876890 DOI: 10.1074/Mcp.M110.003533 |
0.459 |
|
| 2011 |
Li Y, Ting R, Harwig CW, Auf Dem Keller U, Bellac CL, Lange PF, Inkster JAH, Schaffer P, Adam MJ, Ruth TJ, Overall CM, Perrin DM. Towards kit-like 18F-labeling of marimastat, a noncovalent inhibitor drug for in vivo PET imaging cancer associated matrix metalloproteases Medchemcomm. 2: 942-949. DOI: 10.1039/C1Md00117E |
0.69 |
|
| 2010 |
Cox JH, Starr AE, Kappelhoff R, Yan R, Roberts CR, Overall CM. Matrix metalloproteinase 8 deficiency in mice exacerbates inflammatory arthritis through delayed neutrophil apoptosis and reduced caspase 11 expression. Arthritis and Rheumatism. 62: 3645-55. PMID 21120997 DOI: 10.1002/Art.27757 |
0.423 |
|
| 2010 |
auf dem Keller U, Bellac CL, Li Y, Lou Y, Lange PF, Ting R, Harwig C, Kappelhoff R, Dedhar S, Adam MJ, Ruth TJ, Bénard F, Perrin DM, Overall CM. Novel matrix metalloproteinase inhibitor [18F]marimastat-aryltrifluoroborate as a probe for in vivo positron emission tomography imaging in cancer. Cancer Research. 70: 7562-9. PMID 20729277 DOI: 10.1158/0008-5472.Can-10-1584 |
0.701 |
|
| 2010 |
Dezerega A, Osorio C, Mardones J, Mundi V, Dutzan N, Franco M, Gamonal J, Oyarzún A, Overall CM, Hernández M. Monocyte chemotactic protein-3: possible involvement in apical periodontitis chemotaxis. International Endodontic Journal. 43: 902-8. PMID 20646081 DOI: 10.1111/J.1365-2591.2010.01764.X |
0.323 |
|
| 2010 |
Schilling O, Barré O, Huesgen PF, Overall CM. Proteome-wide analysis of protein carboxy termini: C terminomics. Nature Methods. 7: 508-11. PMID 20526347 DOI: 10.1038/Nmeth.1467 |
0.34 |
|
| 2010 |
Prudova A, auf dem Keller U, Butler GS, Overall CM. Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics. Molecular & Cellular Proteomics : McP. 9: 894-911. PMID 20305284 DOI: 10.1074/Mcp.M000050-Mcp201 |
0.485 |
|
| 2010 |
auf dem Keller U, Prudova A, Gioia M, Butler GS, Overall CM. A statistics-based platform for quantitative N-terminome analysis and identification of protease cleavage products. Molecular & Cellular Proteomics : McP. 9: 912-27. PMID 20305283 DOI: 10.1074/Mcp.M000032-Mcp201 |
0.4 |
|
| 2010 |
Sounni NE, Dehne K, van Kempen L, Egeblad M, Affara NI, Cuevas I, Wiesen J, Junankar S, Korets L, Lee J, Shen J, Morrison CJ, Overall CM, Krane SM, Werb Z, et al. Stromal regulation of vessel stability by MMP14 and TGFbeta. Disease Models & Mechanisms. 3: 317-32. PMID 20223936 DOI: 10.1242/Dmm.003863 |
0.401 |
|
| 2010 |
Kleifeld O, Doucet A, auf dem Keller U, Prudova A, Schilling O, Kainthan RK, Starr AE, Foster LJ, Kizhakkedathu JN, Overall CM. Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products. Nature Biotechnology. 28: 281-8. PMID 20208520 DOI: 10.1038/Nbt.1611 |
0.466 |
|
| 2010 |
Dezerega A, Pozo P, Hernández M, Oyarzún A, Rivera O, Dutzan N, Gutiérrez-Fernández A, Overall CM, Garrido M, Alcota M, Ortiz E, Gamonal J. Chemokine monocyte chemoattractant protein-3 in progressive periodontal lesions in patients with chronic periodontitis. Journal of Periodontology. 81: 267-76. PMID 20151806 DOI: 10.1902/Jop.2009.090406 |
0.305 |
|
| 2010 |
Butler GS, Dean RA, Morrison CJ, Overall CM. Identification of cellular MMP substrates using quantitative proteomics: isotope-coded affinity tags (ICAT) and isobaric tags for relative and absolute quantification (iTRAQ). Methods in Molecular Biology (Clifton, N.J.). 622: 451-70. PMID 20135298 DOI: 10.1007/978-1-60327-299-5_26 |
0.481 |
|
| 2010 |
Kappelhoff R, Auf dem Keller U, Overall CM. Analysis of the degradome with the CLIP-CHIP microarray. Methods in Molecular Biology (Clifton, N.J.). 622: 175-93. PMID 20135282 DOI: 10.1007/978-1-60327-299-5_10 |
0.348 |
|
| 2010 |
Wu Y, Dai J, Schmuckler NG, Bakdash N, Yoder MC, Overall CM, Colman RW. Cleaved high molecular weight kininogen inhibits tube formation of endothelial progenitor cells via suppression of matrix metalloproteinase 2 Journal of Thrombosis and Haemostasis. 8: 185-193. PMID 19874467 DOI: 10.1111/J.1538-7836.2009.03662.X |
0.359 |
|
| 2010 |
Rodríguez D, Morrison CJ, Overall CM. Matrix metalloproteinases: what do they not do? New substrates and biological roles identified by murine models and proteomics. Biochimica Et Biophysica Acta. 1803: 39-54. PMID 19800373 DOI: 10.1016/J.Bbamcr.2009.09.015 |
0.52 |
|
| 2010 |
Kleifeld O, Doucet A, Kizhakkedathu JN, Overall CM. System-wide proteomic identification of protease cleavage products by terminal amine isotopic labeling of substrates Nature Protocols. DOI: 10.1038/Nprot.2010.30 |
0.329 |
|
| 2009 |
Butler GS, Overall CM. Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting. Nature Reviews. Drug Discovery. 8: 935-48. PMID 19949400 DOI: 10.1038/Nrd2945 |
0.32 |
|
| 2009 |
Butler GS, Overall CM. Updated biological roles for matrix metalloproteinases and new "intracellular" substrates revealed by degradomics. Biochemistry. 48: 10830-45. PMID 19817485 DOI: 10.1021/Bi901656F |
0.514 |
|
| 2009 |
Morrison CJ, Butler GS, Rodríguez D, Overall CM. Matrix metalloproteinase proteomics: substrates, targets, and therapy. Current Opinion in Cell Biology. 21: 645-53. PMID 19616423 DOI: 10.1016/J.Ceb.2009.06.006 |
0.507 |
|
| 2009 |
Maretzky T, Le Gall SM, Worpenberg-Pietruk S, Eder J, Overall CM, Huang XY, Poghosyan Z, Edwards DR, Blobel CP. Src stimulates fibroblast growth factor receptor-2 shedding by an ADAM15 splice variant linked to breast cancer. Cancer Research. 69: 4573-6. PMID 19487280 DOI: 10.1158/0008-5472.Can-08-4766 |
0.311 |
|
| 2009 |
Starr AE, Overall CM. Chapter 13. Characterizing proteolytic processing of chemokines by mass spectrometry, biochemistry, neo-epitope antibodies and functional assays. Methods in Enzymology. 461: 281-307. PMID 19480924 DOI: 10.1016/S0076-6879(09)05413-5 |
0.329 |
|
| 2009 |
Hwang Q, Cheifetz S, Overall CM, McCulloch CA, Sodek J. Bone sialoprotein does not interact with pro-gelatinase A (MMP-2) or mediate MMP-2 activation. Bmc Cancer. 9: 121. PMID 19386107 DOI: 10.1186/1471-2407-9-121 |
0.675 |
|
| 2009 |
Gioia M, Foster LJ, Overall CM. Cell-based identification of natural substrates and cleavage sites for extracellular proteases by SILAC proteomics. Methods in Molecular Biology (Clifton, N.J.). 539: 131-53. PMID 19377966 DOI: 10.1007/978-1-60327-003-8_8 |
0.473 |
|
| 2009 |
Maretzky T, Yang G, Ouerfelli O, Overall CM, Worpenberg S, Hassiepen U, Eder J, Blobel CP. Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays. The Biochemical Journal. 420: 105-13. PMID 19207106 DOI: 10.1042/Bj20082127 |
0.413 |
|
| 2009 |
Butler GS, Dean RA, Smith D, Overall CM. Membrane protease degradomics: proteomic identification and quantification of cell surface protease substrates. Methods in Molecular Biology (Clifton, N.J.). 528: 159-76. PMID 19153692 DOI: 10.1007/978-1-60327-310-7_12 |
0.434 |
|
| 2009 |
Gioia M, Monaco S, Van Den Steen PE, Sbardella D, Grasso G, Marini S, Overall CM, Opdenakker G, Coletta M. The collagen binding domain of gelatinase A modulates degradation of collagen IV by gelatinase B. Journal of Molecular Biology. 386: 419-34. PMID 19109975 DOI: 10.1016/J.Jmb.2008.12.021 |
0.519 |
|
| 2008 |
Dean RA, Cox JH, Bellac CL, Doucet A, Starr AE, Overall CM. Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influx. Blood. 112: 3455-64. PMID 18660381 DOI: 10.1182/Blood-2007-12-129080 |
0.483 |
|
| 2008 |
Doucet A, Butler GS, Rodríguez D, Prudova A, Overall CM. Metadegradomics: toward in vivo quantitative degradomics of proteolytic post-translational modifications of the cancer proteome. Molecular & Cellular Proteomics : McP. 7: 1925-51. PMID 18596063 DOI: 10.1074/Mcp.R800012-Mcp200 |
0.452 |
|
| 2008 |
Doucet A, Overall CM. Protease proteomics: revealing protease in vivo functions using systems biology approaches. Molecular Aspects of Medicine. 29: 339-58. PMID 18571712 DOI: 10.1016/J.Mam.2008.04.003 |
0.432 |
|
| 2008 |
Lin M, Jackson P, Tester AM, Diaconu E, Overall CM, Blalock JE, Pearlman E. Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro. The American Journal of Pathology. 173: 144-53. PMID 18556780 DOI: 10.2353/Ajpath.2008.080081 |
0.461 |
|
| 2008 |
Butler GS, Dean RA, Tam EM, Overall CM. Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein shedding. Molecular and Cellular Biology. 28: 4896-914. PMID 18505826 DOI: 10.1128/Mcb.01775-07 |
0.773 |
|
| 2008 |
Schilling O, Overall CM. Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites. Nature Biotechnology. 26: 685-94. PMID 18500335 DOI: 10.1038/Nbt1408 |
0.367 |
|
| 2008 |
Cox JH, Dean RA, Roberts CR, Overall CM. Matrix metalloproteinase processing of CXCL11/I-TAC results in loss of chemoattractant activity and altered glycosaminoglycan binding. The Journal of Biological Chemistry. 283: 19389-99. PMID 18411283 DOI: 10.1074/Jbc.M800266200 |
0.5 |
|
| 2008 |
Cheung C, Marchant D, Walker EK, Luo Z, Zhang J, Yanagawa B, Rahmani M, Cox J, Overall C, Senior RM, Luo H, McManus BM. Ablation of matrix metalloproteinase-9 increases severity of viral myocarditis in mice. Circulation. 117: 1574-82. PMID 18332263 DOI: 10.1161/Circulationaha.107.733238 |
0.432 |
|
| 2008 |
Ajami K, Pitman MR, Wilson CH, Park J, Menz RI, Starr AE, Cox JH, Abbott CA, Overall CM, Gorrell MD. Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8. Febs Letters. 582: 819-25. PMID 18275857 DOI: 10.1016/J.Febslet.2008.02.005 |
0.369 |
|
| 2008 |
Folgueras AR, Fueyo A, García-Suárez O, Cox J, Astudillo A, Tortorella P, Campestre C, Gutiérrez-Fernández A, Fanjul-Fernández M, Pennington CJ, Edwards DR, Overall CM, López-Otín C. Collagenase-2 deficiency or inhibition impairs experimental autoimmune encephalomyelitis in mice. The Journal of Biological Chemistry. 283: 9465-74. PMID 18245084 DOI: 10.1074/Jbc.M709522200 |
0.474 |
|
| 2008 |
auf dem Keller U, Doucet A, Overall CM. Protease research in the era of systems biology. Biological Chemistry. 388: 1159-62. PMID 17976008 DOI: 10.1515/Bc.2007.146 |
0.36 |
|
| 2008 |
Marchant D, Cheung C, Walker EK, Luo H, Luo Z, Zhang J, Yanagawa B, Rahmani M, McManus BM, Cox J, Overall C, Senior RM. Response to Letter Regarding Article, “Ablation of Matrix Metalloproteinase-9 Increases Severity of Viral Myocarditis in Mice” Circulation. 118. DOI: 10.1161/Circulationaha.108.794024 |
0.463 |
|
| 2007 |
Kappelhoff R, Overall C. The CLIP-CHIP oligonucleotide microarray: dedicated array for analysis of all protease, nonproteolytic homolog, and inhibitor gene transcripts in human and mouse. Current Protocols in Protein Science. 56. PMID 19365791 DOI: 10.1002/0471140864.Ps2119S56 |
0.302 |
|
| 2007 |
Dean RA, Smith D, Overall CM. Proteomic identification of cellular protease substrates using isobaric tags for relative and absolute quantification (iTRAQ). Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit 21.18. PMID 18429318 DOI: 10.1002/0471140864.Ps2118S49 |
0.399 |
|
| 2007 |
Overall CM, Butler GS. Protease yoga: extreme flexibility of a matrix metalloproteinase. Structure (London, England : 1993). 15: 1159-61. PMID 17937904 DOI: 10.1016/J.Str.2007.10.001 |
0.458 |
|
| 2007 |
Kim M, Hamilton SE, Guddat LW, Overall CM. Plant collagenase: unique collagenolytic activity of cysteine proteases from ginger. Biochimica Et Biophysica Acta. 1770: 1627-35. PMID 17920199 DOI: 10.1016/J.Bbagen.2007.08.003 |
0.306 |
|
| 2007 |
Dean RA, Butler GS, Hamma-Kourbali Y, Delbé J, Brigstock DR, Courty J, Overall CM. Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: disruption of vascular endothelial growth factor (VEGF)/heparin affin regulatory peptide (pleiotrophin) and VEGF/Connective tissue growth factor angiogenic inhibitory complexes by MMP-2 proteolysis. Molecular and Cellular Biology. 27: 8454-65. PMID 17908800 DOI: 10.1128/Mcb.00821-07 |
0.522 |
|
| 2007 |
Wolf K, Wu YI, Liu Y, Geiger J, Tam E, Overall C, Stack MS, Friedl P. Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nature Cell Biology. 9: 893-904. PMID 17618273 DOI: 10.1038/Ncb1616 |
0.749 |
|
| 2007 |
Tester AM, Cox JH, Connor AR, Starr AE, Dean RA, Puente XS, López-OtÃn C, Overall CM. LPS responsiveness and neutrophil chemotaxis in vivo require PMN MMP-8 activity. Plos One. 2: e312. PMID 17375198 DOI: 10.1371/Journal.Pone.0000312 |
0.49 |
|
| 2007 |
Minond D, Lauer-Fields JL, Cudic M, Overall CM, Pei D, Brew K, Moss ML, Fields GB. Differentiation of secreted and membrane-type matrix metalloproteinase activities based on substitutions and interruptions of triple-helical sequences. Biochemistry. 46: 3724-33. PMID 17338550 DOI: 10.1021/Bi062199J |
0.512 |
|
| 2007 |
Butler GS, Overall CM. Proteomic validation of protease drug targets: pharmacoproteomics of matrix metalloproteinase inhibitor drugs using isotope-coded affinity tag labelling and tandem mass spectrometry. Current Pharmaceutical Design. 13: 263-70. PMID 17313360 DOI: 10.2174/138161207779313524 |
0.373 |
|
| 2007 |
Overall CM, Blobel CP. In search of partners: linking extracellular proteases to substrates. Nature Reviews. Molecular Cell Biology. 8: 245-57. PMID 17299501 DOI: 10.1038/Nrm2120 |
0.374 |
|
| 2007 |
Iida J, Wilhelmson KL, Ng J, Lee P, Morrison C, Tam E, Overall CM, McCarthy JB. Cell surface chondroitin sulfate glycosaminoglycan in melanoma: role in the activation of pro-MMP-2 (pro-gelatinase A). The Biochemical Journal. 403: 553-63. PMID 17217338 DOI: 10.1042/Bj20061176 |
0.769 |
|
| 2007 |
Dean RA, Overall CM. Proteomics discovery of metalloproteinase substrates in the cellular context by iTRAQ labeling reveals a diverse MMP-2 substrate degradome. Molecular & Cellular Proteomics : McP. 6: 611-23. PMID 17200105 DOI: 10.1074/Mcp.M600341-Mcp200 |
0.547 |
|
| 2006 |
Schilling O, Overall CM. Proteomic discovery of protease substrates. Current Opinion in Chemical Biology. 11: 36-45. PMID 17194619 DOI: 10.1016/J.Cbpa.2006.11.037 |
0.428 |
|
| 2006 |
Vergote D, Butler GS, Ooms M, Cox JH, Silva C, Hollenberg MD, Jhamandas JH, Overall CM, Power C. Proteolytic processing of SDF-1alpha reveals a change in receptor specificity mediating HIV-associated neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 103: 19182-7. PMID 17148615 DOI: 10.1073/Pnas.0604678103 |
0.359 |
|
| 2006 |
Minond D, Lauer-Fields JL, Cudic M, Overall CM, Pei D, Brew K, Visse R, Nagase H, Fields GB. The roles of substrate thermal stability and P2 and P1' subsite identity on matrix metalloproteinase triple-helical peptidase activity and collagen specificity. The Journal of Biological Chemistry. 281: 38302-13. PMID 17065155 DOI: 10.1074/Jbc.M606004200 |
0.511 |
|
| 2006 |
Lee H, Overall CM, McCulloch CA, Sodek J. A critical role for the membrane-type 1 matrix metalloproteinase in collagen phagocytosis. Molecular Biology of the Cell. 17: 4812-26. PMID 16971509 DOI: 10.1091/Mbc.E06-06-0486 |
0.69 |
|
| 2006 |
Morrison CJ, Overall CM. TIMP independence of matrix metalloproteinase (MMP)-2 activation by membrane type 2 (MT2)-MMP is determined by contributions of both the MT2-MMP catalytic and hemopexin C domains. The Journal of Biological Chemistry. 281: 26528-39. PMID 16825197 DOI: 10.1074/Jbc.M603331200 |
0.511 |
|
| 2006 |
Hasan L, Mazzucchelli L, Liebi M, Lis M, Hunger RE, Tester A, Overall CM, Wolf M. Function of liver activation-regulated chemokine/CC chemokine ligand 20 is differently affected by cathepsin B and cathepsin D processing. Journal of Immunology (Baltimore, Md. : 1950). 176: 6512-22. PMID 16709808 DOI: 10.4049/Jimmunol.176.11.6512 |
0.355 |
|
| 2006 |
Overall CM, Dean RA. Degradomics: systems biology of the protease web. Pleiotropic roles of MMPs in cancer. Cancer Metastasis Reviews. 25: 69-75. PMID 16680573 DOI: 10.1007/S10555-006-7890-0 |
0.555 |
|
| 2006 |
Overall CM, Kleifeld O. Towards third generation matrix metalloproteinase inhibitors for cancer therapy British Journal of Cancer. 94: 941-946. PMID 16538215 DOI: 10.1038/Sj.Bjc.6603043 |
0.466 |
|
| 2006 |
Overall CM, Kleifeld O. Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy. Nature Reviews. Cancer. 6: 227-39. PMID 16498445 DOI: 10.1038/Nrc1821 |
0.453 |
|
| 2005 |
Nisato RE, Hosseini G, Sirrenberg C, Butler GS, Crabbe T, Docherty AJ, Wiesner M, Murphy G, Overall CM, Goodman SL, Pepper MS. Dissecting the role of matrix metalloproteinases (MMP) and integrin alpha(v)beta3 in angiogenesis in vitro: absence of hemopexin C domain bioactivity, but membrane-Type 1-MMP and alpha(v)beta3 are critical. Cancer Research. 65: 9377-87. PMID 16230401 DOI: 10.1158/0008-5472.Can-05-1512 |
0.46 |
|
| 2005 |
Nour N, Mayer G, Mort JS, Salvas A, Mbikay M, Morrison CJ, Overall CM, Seidah NG. The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases Molecular Biology of the Cell. 16: 5215-5226. PMID 16135528 DOI: 10.1091/Mbc.E05-06-0504 |
0.357 |
|
| 2005 |
Overall CM. Dilating the degradome: matrix metalloproteinase 2 (MMP-2) cuts to the heart of the matter. The Biochemical Journal. 383: e5-7. PMID 15508185 DOI: 10.1042/Bj20041433 |
0.488 |
|
| 2004 |
Pelman GR, Morrison CJ, Overall CM. Pivotal molecular determinants of peptidic and collagen triple helicase activities reside in the S3' subsite of matrix metalloproteinase 8 (MMP-8): the role of hydrogen bonding potential of ASN188 and TYR189 and the connecting cis bond. The Journal of Biological Chemistry. 280: 2370-7. PMID 15533938 DOI: 10.1074/Jbc.M409603200 |
0.458 |
|
| 2004 |
Tam EM, Moore TR, Butler GS, Overall CM. Characterization of the distinct collagen binding, helicase and cleavage mechanisms of matrix metalloproteinase 2 and 14 (gelatinase A and MT1-MMP): the differential roles of the MMP hemopexin c domains and the MMP-2 fibronectin type II modules in collagen triple helicase activities. The Journal of Biological Chemistry. 279: 43336-44. PMID 15292230 DOI: 10.1074/Jbc.M407186200 |
0.765 |
|
| 2004 |
Overall CM, Tam EM, Kappelhoff R, Connor A, Ewart T, Morrison CJ, Puente X, López-Otín C, Seth A. Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors. Biological Chemistry. 385: 493-504. PMID 15255181 DOI: 10.1515/Bc.2004.058 |
0.772 |
|
| 2004 |
Tam EM, Morrison CJ, Wu YI, Stack MS, Overall CM. Membrane protease proteomics: Isotope-coded affinity tag MS identification of undescribed MT1-matrix metalloproteinase substrates. Proceedings of the National Academy of Sciences of the United States of America. 101: 6917-22. PMID 15118097 DOI: 10.1073/Pnas.0305862101 |
0.779 |
|
| 2004 |
Butler GS, Tam EM, Overall CM. The canonical methionine 392 of matrix metalloproteinase 2 (gelatinase A) is not required for catalytic efficiency or structural integrity: probing the role of the methionine-turn in the metzincin metalloprotease superfamily. The Journal of Biological Chemistry. 279: 15615-20. PMID 14732714 DOI: 10.1074/Jbc.M312727200 |
0.772 |
|
| 2003 |
Balbín M, Fueyo A, Tester AM, Pendás AM, Pitiot AS, Astudillo A, Overall CM, Shapiro SD, López-Otín C. Loss of collagenase-2 confers increased skin tumor susceptibility to male mice. Nature Genetics. 35: 252-7. PMID 14517555 DOI: 10.1038/Ng1249 |
0.431 |
|
| 2003 |
Zhang K, McQuibban GA, Silva C, Butler GS, Johnston JB, Holden J, Clark-Lewis I, Overall CM, Power C. HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration. Nature Neuroscience. 6: 1064-71. PMID 14502291 DOI: 10.1038/Nn1127 |
0.757 |
|
| 2003 |
Puente XS, Sánchez LM, Overall CM, López-Otín C. Human and mouse proteases: a comparative genomic approach. Nature Reviews. Genetics. 4: 544-58. PMID 12838346 DOI: 10.1038/Nrg1111 |
0.309 |
|
| 2003 |
Overall CM. Molecular determinants of metalloproteinase substrate specificity: matrix metalloproteinase substrate binding domains, modules, and exosites. Molecular Biotechnology. 22: 51-86. PMID 12353914 DOI: 10.1385/Mb:22:1:051 |
0.488 |
|
| 2002 |
Radomski A, Jurasz P, Sanders EJ, Overall CM, Bigg HF, Edwards DR, Radomski MW. Identification, regulation and role of tissue inhibitor of metalloproteinases-4 (TIMP-4) in human platelets British Journal of Pharmacology. 137: 1330-1338. PMID 12466243 DOI: 10.1038/Sj.Bjp.0704936 |
0.368 |
|
| 2002 |
Overall CM, McQuibban GA, Clark-Lewis I. Discovery of chemokine substrates for matrix metalloproteinases by exosite scanning: a new tool for degradomics. Biological Chemistry. 383: 1059-66. PMID 12437088 DOI: 10.1515/Bc.2002.114 |
0.792 |
|
| 2002 |
Kai HS, Butler GS, Morrison CJ, King AE, Pelman GR, Overall CM. Utilization of a novel recombinant myoglobin fusion protein expression system to characterize the tissue inhibitor of metalloproteinase (TIMP)-4 and TIMP-2 C-terminal domain and tails by mutagenesis. The importance of acidic residues in binding the MMP-2 hemopexin C-domain. The Journal of Biological Chemistry. 277: 48696-707. PMID 12374789 DOI: 10.1074/Jbc.M209177200 |
0.481 |
|
| 2002 |
Overall CM, López-Otín C. Strategies for MMP inhibition in cancer: innovations for the post-trial era. Nature Reviews. Cancer. 2: 657-72. PMID 12209155 DOI: 10.1038/Nrc884 |
0.489 |
|
| 2002 |
McQuibban GA, Gong JH, Wong JP, Wallace JL, Clark-Lewis I, Overall CM. Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo. Blood. 100: 1160-7. PMID 12149192 DOI: 10.1182/Blood.V100.4.1160.H81602001160_1160_1167 |
0.79 |
|
| 2002 |
Tam EM, Wu YI, Butler GS, Stack MS, Overall CM. Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage. The Journal of Biological Chemistry. 277: 39005-14. PMID 12145314 DOI: 10.1074/Jbc.M206874200 |
0.768 |
|
| 2002 |
López-Otín C, Overall CM. Protease degradomics: a new challenge for proteomics. Nature Reviews. Molecular Cell Biology. 3: 509-19. PMID 12094217 DOI: 10.1038/Nrm858 |
0.308 |
|
| 2002 |
Butler GS, Sim D, Tam E, Devine D, Overall CM. Mannose-binding lectin (MBL) mutants are susceptible to matrix metalloproteinase proteolysis: potential role in human MBL deficiency. The Journal of Biological Chemistry. 277: 17511-9. PMID 11891230 DOI: 10.1074/Jbc.M201461200 |
0.765 |
|
| 2002 |
Saad S, Gottlieb DJ, Bradstock KF, Overall CM, Bendall LJ. Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts. Cancer Research. 62: 283-9. PMID 11782389 |
0.363 |
|
| 2002 |
OVERALL C, KING A, SAM D, ONG A, LAU T, WALLON U, DECLERCK Y, ATHERSTONE J. Identification of the TIMP-2 binding site on the hemopexin domain of human gelatinase A by site-directed mutagenesis International Journal of Experimental Pathology. 79: A40-A41. DOI: 10.1046/J.1365-2613.1998.T01-31-750408.X |
0.306 |
|
| 2001 |
Morrison CJ, Butler GS, Bigg HF, Roberts CR, Soloway PD, Overall CM. Cellular activation of MMP-2 (gelatinase A) by MT2-MMP occurs via a TIMP-2-independent pathway. The Journal of Biological Chemistry. 276: 47402-10. PMID 11584019 DOI: 10.1074/Jbc.M108643200 |
0.512 |
|
| 2001 |
McQuibban GA, Butler GS, Gong JH, Bendall L, Power C, Clark-Lewis I, Overall CM. Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1. The Journal of Biological Chemistry. 276: 43503-8. PMID 11571304 DOI: 10.1074/Jbc.M107736200 |
0.793 |
|
| 2001 |
Ellerbroek SM, Wu YI, Overall CM, Stack MS. Functional interplay between type I collagen and cell surface matrix metalloproteinase activity. The Journal of Biological Chemistry. 276: 24833-42. PMID 11331272 DOI: 10.1074/Jbc.M005631200 |
0.504 |
|
| 2001 |
Kang T, Yi J, Guo A, Wang X, Overall CM, Jiang W, Elde R, Borregaard N, Pei D. Subcellular Distribution and Cytokine- and Chemokine-regulated Secretion of Leukolysin/MT6-MMP/MMP-25 in Neutrophils Journal of Biological Chemistry. 276: 21960-21968. PMID 11282999 DOI: 10.1074/Jbc.M007997200 |
0.495 |
|
| 2001 |
Toth M, Bernardo MM, Gervasi DC, Soloway PD, Wang Z, Bigg HF, Overall CM, DeClerck YA, Tschesche H, Cher ML, Brown S, Mobashery S, Fridman R. Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (Membrane type 1)-MMP-dependent activation of pro-MMP-2. The Journal of Biological Chemistry. 275: 41415-23. PMID 10998420 DOI: 10.1074/Jbc.M006871200 |
0.406 |
|
| 2001 |
Overall CM. Matrix MetaIIoproteinase Substrate Binding Domains, Modules and Exosites Methods of Molecular Biology. 151: 79-120. DOI: 10.1385/1-59259-046-2:079 |
0.373 |
|
| 2000 |
Overall CM, Tam E, McQuibban GA, Morrison C, Wallon UM, Bigg HF, King AE, Roberts CR. Domain interactions in the gelatinase A.TIMP-2.MT1-MMP activation complex. The ectodomain of the 44-kDa form of membrane type-1 matrix metalloproteinase does not modulate gelatinase A activation. The Journal of Biological Chemistry. 275: 39497-506. PMID 10991943 DOI: 10.1074/jbc.M005932200 |
0.77 |
|
| 2000 |
McQuibban GA, Gong JH, Tam EM, McCulloch CA, Clark-Lewis I, Overall CM. Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3. Science (New York, N.Y.). 289: 1202-6. PMID 10947989 DOI: 10.1126/Science.289.5482.1202 |
0.807 |
|
| 2000 |
Bhide VM, Smith L, Overall CM, Birek P, McCulloch CA. Use of a fluorogenic septapeptide matrix metalloproteinase assay to assess responses to periodontal treatment. Journal of Periodontology. 71: 690-700. PMID 10872948 DOI: 10.1902/Jop.2000.71.5.690 |
0.422 |
|
| 2000 |
Martin-De Las Heras S, Valenzuela A, Overall CM. The matrix metalloproteinase gelatinase A in human dentine. Archives of Oral Biology. 45: 757-65. PMID 10869489 DOI: 10.1016/S0003-9969(00)00052-2 |
0.311 |
|
| 2000 |
Brayer GD, Sidhu G, Maurus R, Rydberg EH, Braun C, Wang Y, Nguyen NT, Overall CM, Withers SG. Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques. Biochemistry. 39: 4778-91. PMID 10769135 DOI: 10.1021/Bi9921182 |
0.332 |
|
| 1999 |
Mancini S, Romanelli R, Laschinger CA, Overall CM, Sodek J, McCulloch CA. Assessment of a novel screening test for neutrophil collagenase activity in the diagnosis of periodontal diseases. Journal of Periodontology. 70: 1292-302. PMID 10588492 DOI: 10.1902/Jop.1999.70.11.1292 |
0.603 |
|
| 1999 |
Overall CM, King AE, Bigg HF, McQuibban A, Atherstone J, Sam DK, Ong AD, Lau TT, Wallon UM, DeClerck YA, Tam E. Identification of the TIMP-2 binding site on the gelatinase A hemopexin C-domain by site-directed mutagenesis and the yeast two-hybrid system. Annals of the New York Academy of Sciences. 878: 747-53. PMID 10415826 DOI: 10.1111/J.1749-6632.1999.Tb07780.X |
0.672 |
|
| 1999 |
Romanelli R, Mancini S, Laschinger C, Overall CM, Sodek J, McCulloch CA. Activation of neutrophil collagenase in periodontitis. Infection and Immunity. 67: 2319-26. PMID 10225890 DOI: 10.1128/Iai.67.5.2319-2326.1999 |
0.679 |
|
| 1999 |
Rydberg EH, Sidhu G, Vo HC, Hewitt J, Côte HC, Wang Y, Numao S, MacGillivray RT, Overall CM, Brayer GD, Withers SG. Cloning, mutagenesis, and structural analysis of human pancreatic alpha-amylase expressed in Pichia pastoris. Protein Science : a Publication of the Protein Society. 8: 635-43. PMID 10091666 DOI: 10.1110/Ps.8.3.635 |
0.356 |
|
| 1998 |
Steffensen B, Bigg HF, Overall CM. The involvement of the fibronectin type II-like modules of human gelatinase A in cell surface localization and activation. The Journal of Biological Chemistry. 273: 20622-8. PMID 9685420 DOI: 10.1074/Jbc.273.32.20622 |
0.41 |
|
| 1998 |
Sutinen M, Kainulainen T, Hurskainen T, Vesterlund E, Alexander JP, Overall CM, Sorsa T, Salo T. Expression of matrix metalloproteinases (MMP-1 and -2) and their inhibitors (TIMP-1, -2 and -3) in oral lichen planus, dysplasia, squamous cell carcinoma and lymph node metastasis British Journal of Cancer. 77: 2239-2245. PMID 9649139 DOI: 10.1038/Bjc.1998.372 |
0.434 |
|
| 1997 |
Maurus R, Overall CM, Bogumil R, Luo Y, Mauk AG, Smith M, Brayer GD. A myoglobin variant with a polar substitution in a conserved hydrophobic cluster in the heme binding pocket. Biochimica Et Biophysica Acta. 1341: 1-13. PMID 9300804 DOI: 10.1016/S0167-4838(97)00064-2 |
0.392 |
|
| 1997 |
Iamaroon A, Wallon UM, Overall CM, Diewert VM. Expression of 72-kDa gelatinase (matrix metalloproteinase-2) in the developing mouse craniofacial complex. Archives of Oral Biology. 41: 1109-19. PMID 9134100 DOI: 10.1016/S0003-9969(96)00097-0 |
0.466 |
|
| 1995 |
Overall CM. Repression of tissue inhibitor of matrix metalloproteinase expression by all-trans-retinoic acid in rat bone cell populations: comparison with transforming growth factor-beta 1. Journal of Cellular Physiology. 164: 17-25. PMID 7790389 DOI: 10.1002/Jcp.1041640104 |
0.396 |
|
| 1995 |
Steffensen B, Wallon UM, Overall CM. Extracellular matrix binding properties of recombinant fibronectin type II-like modules of human 72-kDa gelatinase/type IV collagenase. High affinity binding to native type I collagen but not native type IV collagen. The Journal of Biological Chemistry. 270: 11555-66. PMID 7744795 DOI: 10.1074/Jbc.270.19.11555 |
0.405 |
|
| 1994 |
Overall CM. Regulation of tissue inhibitor of matrix metalloproteinase expression. Annals of the New York Academy of Sciences. 732: 51-64. PMID 7978851 DOI: 10.1111/J.1749-6632.1994.Tb24724.X |
0.413 |
|
| 1993 |
Dedhar S, Saulnier R, Nagle R, Overall CM. Specific alterations in the expression of alpha 3 beta 1 and alpha 6 beta 4 integrins in highly invasive and metastatic variants of human prostate carcinoma cells selected by in vitro invasion through reconstituted basement membrane. Clinical & Experimental Metastasis. 11: 391-400. PMID 8375114 DOI: 10.1007/Bf00132982 |
0.307 |
|
| 1992 |
Sodek J, Overall CM. Matrix metalloproteinases in periodontal tissue remodelling. Matrix (Stuttgart, Germany). Supplement. 1: 352-62. PMID 1480060 |
0.619 |
|
| 1992 |
Overall CM, Sodek J. Reciprocal regulation of collagenase, 72 kDa-gelatinase, and TIMP gene expression and protein synthesis in human fibroblasts induced by concanavalin A. Matrix (Stuttgart, Germany). Supplement. 1: 209-11. PMID 1480028 |
0.53 |
|
| 1991 |
Wrana JL, Kubota T, Zhang Q, Overall CM, Aubin JE, Butler WT, Sodek J. Regulation of transformation-sensitive secreted phosphoprotein (SPPI/osteopontin) expression by transforming growth factor-beta. Comparisons with expression of SPARC (secreted acidic cysteine-rich protein). The Biochemical Journal. 273: 523-31. PMID 1996953 DOI: 10.1042/Bj2730523 |
0.669 |
|
| 1991 |
Kasugai S, Zhang Q, Overall CM, Wrana JL, Butler WT, Sodek J. Differential regulation of the 55 and 44 kDa forms of secreted phosphoprotein 1 (SPP-1, osteopontin) in normal and transformed rat bone cells by osteotropic hormones, growth factors and a tumor promoter. Bone and Mineral. 13: 235-50. PMID 1863811 DOI: 10.1016/0169-6009(91)90071-7 |
0.66 |
|
| 1991 |
Overall CM, Wrana JL, Sodek J. Induction of formative and resorptive cellular phenotypes in human gingival fibroblasts by TGF-beta 1 and concanavalin A: regulation of matrix metalloproteinases and TIMP. Journal of Periodontal Research. 26: 279-82. PMID 1831853 DOI: 10.1111/J.1600-0765.1991.Tb01658.X |
0.702 |
|
| 1991 |
Wrana JL, Overall CM, Sodek J. Regulation of the expression of a secreted acidic protein rich in cysteine (SPARC) in human fibroblasts by transforming growth factor beta. Comparison of transcriptional and post-transcriptional control with fibronectin and type I collagen. European Journal of Biochemistry. 197: 519-28. PMID 1709099 DOI: 10.1111/J.1432-1033.1991.Tb15940.X |
0.634 |
|
| 1991 |
Lee W, Aitken S, Kulkarni G, Birek P, Overall CM, Sodek J, McCulloch CA. Collagenase activity in recurrent periodontitis: relationship to disease progression and doxycycline therapy. Journal of Periodontal Research. 26: 479-85. PMID 1662266 DOI: 10.1111/J.1600-0765.1991.Tb01798.X |
0.56 |
|
| 1991 |
Overall CM, Sodek J, McCulloch CA, Birek P. Evidence for polymorphonuclear leukocyte collagenase and 92-kilodalton gelatinase in gingival crevicular fluid. Infection and Immunity. 59: 4687-92. PMID 1657787 DOI: 10.1128/Iai.59.12.4687-4692.1991 |
0.557 |
|
| 1991 |
Overall CM, Wrana JL, Sodek J. Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression. The Journal of Biological Chemistry. 266: 14064-71. PMID 1649834 |
0.59 |
|
| 1991 |
OVERALL CM. Recent Advances in Matrix Metalloproteinase Research. Trends in Glycoscience and Glycotechnology. 3: 384-399. DOI: 10.4052/Tigg.3.384 |
0.464 |
|
| 1990 |
Overall CM, Sodek J. Concanavalin A produces a matrix-degradative phenotype in human fibroblasts. Induction and endogenous activation of collagenase, 72-kDa gelatinase, and Pump-1 is accompanied by the suppression of the tissue inhibitor of matrix metalloproteinases. The Journal of Biological Chemistry. 265: 21141-51. PMID 2174435 |
0.658 |
|
| 1990 |
Gangbar S, Overall CM, McCulloch CA, Sodek J. Identification of polymorphonuclear leukocyte collagenase and gelatinase activities in mouthrinse samples: correlation with periodontal disease activity in adult and juvenile periodontitis. Journal of Periodontal Research. 25: 257-67. PMID 2170617 DOI: 10.1111/J.1600-0765.1990.Tb00914.X |
0.578 |
|
| 1989 |
Overall CM, Limeback H. Identification and characterization of enamel proteinases isolated from developing enamel. Amelogeninolytic serine proteinases are associated with enamel maturation in pig. The Biochemical Journal. 256: 965-72. PMID 3223966 DOI: 10.1042/Bj2560965 |
0.421 |
|
| 1989 |
Overall CM, Wrana JL, Sodek J. Transforming growth factor-beta regulation of collagenase, 72 kDa-progelatinase, TIMP and PAI-1 expression in rat bone cell populations and human fibroblasts. Connective Tissue Research. 20: 289-94. PMID 2558843 DOI: 10.3109/03008208909023899 |
0.649 |
|
| 1989 |
Overall CM, Wrana JL, Sodek J. Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-beta. The Journal of Biological Chemistry. 264: 1860-9. PMID 2536374 |
0.554 |
|
| 1988 |
Drouin L, Overall CM, Sodek J. Identification of matrix metalloendoproteinase inhibitor (TIMP) in human parotid and submandibular saliva: partial purification and characterization. Journal of Periodontal Research. 23: 370-7. PMID 2851041 DOI: 10.1111/J.1600-0765.1988.Tb01615.X |
0.621 |
|
| 1988 |
Otsuka K, Pitaru S, Overall CM, Aubin JE, Sodek J. Biochemical comparison of fibroblast populations from different periodontal tissues: characterization of matrix protein and collagenolytic enzyme synthesis. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 66: 167-76. PMID 2838055 DOI: 10.1139/O88-023 |
0.618 |
|
| 1987 |
Overall CM, Sodek J. Initial characterization of a neutral metalloproteinase, active on native 3/4-collagen fragments, synthesized by ROS 17/2.8 osteoblastic cells, periodontal fibroblasts, and identified in gingival crevicular fluid. Journal of Dental Research. 66: 1271-82. PMID 3040831 DOI: 10.1177/00220345870660071201 |
0.654 |
|
| 1987 |
Overall CM, Wiebkin OW, Thonard JC. Demonstration of tissue collagenase activity in vivo and its relationship to inflammation severity in human gingiva. Journal of Periodontal Research. 22: 81-8. PMID 3035163 DOI: 10.1111/J.1600-0765.1987.Tb01544.X |
0.377 |
|
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