Year |
Citation |
Score |
2021 |
Taylor RE, Trentadue K, Chang CF, Nalin A. Enantioselective Total Synthesis of the Putative Biosynthetic Intermediate Ambruticin J. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33887073 DOI: 10.1002/chem.202100975 |
0.321 |
|
2019 |
Henry JL, Wilson MR, Mulligan MP, Quinn TR, Sackett DL, Taylor RE. Synthesis, conformational preferences, and biological activity of conformational analogues of the microtubule-stabilizing agents, (-)-zampanolide and (-)-dactylolide. Medchemcomm. 10: 800-805. PMID 31191870 DOI: 10.1039/C9Md00164F |
0.499 |
|
2018 |
Granatosky EA, DiPrimio N, Pickering JRE, Stevens DC, Perlstein EO, Taylor RE. GEX1A, a Polyketide from Streptomyces chromofuscus, Corrects the Cellular Defects Associated with Niemann-Pick Type C1 in Human Fibroblasts. Journal of Natural Products. PMID 30188717 DOI: 10.1021/Acs.Jnatprod.8B00314 |
0.529 |
|
2018 |
Dodge GJ, Ronnow D, Taylor RE, Smith JL. Molecular Basis for Olefin Rearrangement in the Gephyronic Acid Polyketide Synthase. Acs Chemical Biology. PMID 30179448 DOI: 10.1021/Acschembio.8B00645 |
0.353 |
|
2018 |
Larsen EM, Chang CF, Sakata-Kato T, Arico JW, Lombardo VM, Wirth DF, Taylor RE. Conformation-guided analogue design identifies potential antimalarial compounds through inhibition of mitochondrial respiration. Organic & Biomolecular Chemistry. PMID 30009295 DOI: 10.1039/C8Ob01257A |
0.353 |
|
2017 |
Woods LM, Arico JW, Frein JD, Sackett DL, Taylor RE. Synthesis and Biological Evaluation of 7-Deoxy-Epothilone Analogues. International Journal of Molecular Sciences. 18. PMID 28304361 DOI: 10.3390/Ijms18030648 |
0.336 |
|
2016 |
Wagner DT, Stevens DC, Mehaffey MR, Manion HR, Taylor RE, Brodbelt JS, Keatinge-Clay AT. α-Methylation follows condensation in the gephyronic acid modular polyketide synthase. Chemical Communications (Cambridge, England). PMID 27346052 DOI: 10.1039/C6Cc04418B |
0.721 |
|
2015 |
Chang CF, Stefan E, Taylor RE. Total Synthesis and Structural Reassignment of Lyngbyaloside C Highlighted by Intermolecular Ketene Esterification. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 10681-6. PMID 26101039 DOI: 10.1002/Chem.201502132 |
0.693 |
|
2015 |
Larsen EM, Wilson MR, Taylor RE. Conformation-activity relationships of polyketide natural products. Natural Product Reports. 32: 1183-206. PMID 25974024 DOI: 10.1039/C5Np00014A |
0.456 |
|
2015 |
Naini A, Muthukumar Y, Raja A, Franke R, Harrier I, Smith AB, Lee D, Taylor RE, Sasse F, Kalesse M. The synthesis and biological evaluation of desepoxyisotedanolide and a comparison with desepoxytedanolide. Angewandte Chemie (International Ed. in English). 54: 6935-9. PMID 25914374 DOI: 10.1002/Anie.201501526 |
0.753 |
|
2015 |
Stefan E, Taylor RE. 1,5-Hydride transfer protocol for the synthesis of β-branched polyketide structural units Tetrahedron Letters. 56: 3416-3419. DOI: 10.1016/J.Tetlet.2015.01.020 |
0.667 |
|
2015 |
Naini A, Muthukumar Y, Raja A, Franke R, Harrier I, Smith AB, Lee D, Taylor RE, Sasse F, Kalesse M. Die Synthese und biologische Validierung von Desepoxyisotedanolid und dessen Vergleich mit Desepoxytedanolid Angewandte Chemie. 127: 7039-7043. DOI: 10.1002/Ange.201501526 |
0.72 |
|
2014 |
Stevens DC, Young J, Carmichael R, Tan J, Taylor RE. Draft Genome Sequence of Gephyronic Acid Producer Cystobacter violaceus Strain Cb vi76. Genome Announcements. 2. PMID 25502681 DOI: 10.1128/Genomea.01299-14 |
0.645 |
|
2013 |
Young J, Stevens DC, Carmichael R, Tan J, Rachid S, Boddy CN, Müller R, Taylor RE. Elucidation of gephyronic acid biosynthetic pathway revealed unexpected SAM-dependent methylations. Journal of Natural Products. 76: 2269-76. PMID 24298873 DOI: 10.1021/Np400629V |
0.755 |
|
2013 |
Larsen EM, Wilson MR, Zajicek J, Taylor RE. Conformational preferences of zampanolide and dactylolide. Organic Letters. 15: 5246-9. PMID 24102367 DOI: 10.1021/Ol402462H |
0.393 |
|
2013 |
Stefan E, Nalin AP, Taylor RE. Concise enantioselective synthesis of diospongins A and B. Tetrahedron. 69: 7706-7712. PMID 24058215 DOI: 10.1016/J.Tet.2013.05.081 |
0.674 |
|
2013 |
Wilson MR, Taylor RE. Strained alkenes in natural product synthesis. Angewandte Chemie (International Ed. in English). 52: 4078-87. PMID 23450661 DOI: 10.1002/Anie.201207712 |
0.442 |
|
2013 |
Muthukumar Y, Roy M, Raja A, Taylor RE, Sasse F. The marine polyketide myriaporone 3/4 stalls translation by targeting the elongation phase. Chembiochem : a European Journal of Chemical Biology. 14: 260-4. PMID 23303710 DOI: 10.1002/Cbic.201200522 |
0.523 |
|
2013 |
Wilson MR, Taylor RE. Gespannte Moleküle in der Naturstoffsynthese Angewandte Chemie. 125: 4170-4180. DOI: 10.1002/Ange.201207712 |
0.364 |
|
2012 |
Wilson MR, Taylor RE. Toward an enantioselective synthesis of (-)-zampanolide: preparation of the C9-C20 region. Organic Letters. 14: 3408-11. PMID 22720980 DOI: 10.1021/Ol301383A |
0.518 |
|
2012 |
Stefan E, Taylor RE. Stereoselective synthesis of the C9-C19 fragment of lyngbyaloside B and C via ether transfer. Organic Letters. 14: 3490-3. PMID 22716968 DOI: 10.1021/Ol301455P |
0.649 |
|
2012 |
Zhao Z, Taylor RE. Rapid access to conformational analogues of (+)-peloruside A. Organic Letters. 14: 669-71. PMID 22235754 DOI: 10.1021/Ol203268T |
0.356 |
|
2011 |
Anderl T, Nicolas L, Münkemer J, Baro A, Sasse F, Steinmetz H, Jansen R, Höfle G, Taylor RE, Laschat S. Gephyronic acid, a missing link between polyketide inhibitors of eukaryotic protein synthesis (part II): Total synthesis of gephyronic acid. Angewandte Chemie (International Ed. in English). 50: 942-5. PMID 21246697 DOI: 10.1002/Anie.201005605 |
0.611 |
|
2011 |
Nicolas L, Anderl T, Sasse F, Steinmetz H, Jansen R, Höfle G, Laschat S, Taylor RE. Gephyronic acid, a missing link between polyketide inhibitors of eukaryotic protein synthesis (part I): Structural revision and stereochemical assignment of gephyronic acid. Angewandte Chemie (International Ed. in English). 50: 938-41. PMID 21246696 DOI: 10.1002/Anie.201005530 |
0.604 |
|
2011 |
Young J, Leliaert A, Schafer ZT, Taylor RE. Abstract C67: Gene expression profiling with human breast cancer cell lines exposed to gephyronic acid Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-C67 |
0.546 |
|
2011 |
Anderl T, Nicolas L, Münkemer J, Muthukumar Y, Baro A, Frey W, Sasse F, Taylor RE, Laschat S. Synthesis and biological evaluation of gephyronic acid derivatives: Initial steps towards the identification of the biological target of polyketide inhibitors of eukaryotic protein synthesis European Journal of Organic Chemistry. 7294-7307. DOI: 10.1002/Ejoc.201101129 |
0.659 |
|
2010 |
Liu K, Arico JW, Taylor RE. Application of stereoselective ether transfer to the synthesis of isotactic polyethers. The Journal of Organic Chemistry. 75: 3953-7. PMID 20481506 DOI: 10.1021/Jo100094D |
0.399 |
|
2010 |
Anderl T, Nicolas L, Münkemer J, Baro A, Sasse F, Steinmetz H, Jansen R, Höfle G, Taylor RE, Laschat S. Gephyronsäure, ein fehlendes Bindeglied zwischen Polyketid-Inhibitoren der eukaryotischen Proteinsynthese (Teil II): Totalsynthese Angewandte Chemie. 123: 972-975. DOI: 10.1002/Ange.201005605 |
0.523 |
|
2010 |
Nicolas L, Anderl T, Sasse F, Steinmetz H, Jansen R, Höfle G, Laschat S, Taylor RE. Gephyronsäure, ein fehlendes Bindeglied zwischen Polyketid- Inhibitoren der eukaryotischen Proteinsynthese (Teil I): Strukturrevision und stereochemische Zuordnung Angewandte Chemie. 123: 968-971. DOI: 10.1002/Ange.201005530 |
0.549 |
|
2009 |
Frein JD, Taylor RE, Sackett DL. New sources of chemical diversity inspired by biosynthesis: rational design of a potent epothilone analogue. Organic Letters. 11: 3186-9. PMID 19572566 DOI: 10.1021/Ol900971R |
0.302 |
|
2009 |
Daly EM, Taylor RE. Entropy and enthalpy in the activity of Tubulin-based antimitotic agents Current Chemical Biology. 3: 47-59. DOI: 10.2174/2212796810903010047 |
0.586 |
|
2008 |
Kartika R, Gruffi TR, Taylor RE. Concise enantioselective total synthesis of neopeltolide macrolactone highlighted by ether transfer. Organic Letters. 10: 5047-50. PMID 18855401 DOI: 10.1021/Ol802254Z |
0.733 |
|
2008 |
Taylor RE. Tedanolide and the evolution of polyketide inhibitors of eukaryotic protein synthesis. Natural Product Reports. 25: 854-61. PMID 18820754 DOI: 10.1039/B805700C |
0.342 |
|
2008 |
Young J, Taylor RE. Evolution of polyketides: post-PKS processing in the formation of spiroketals. Natural Product Reports. 25: 651-5. PMID 18663388 DOI: 10.1039/B719088N |
0.54 |
|
2008 |
Kartika R, Frein JD, Taylor RE. Electrophile-induced ether transfer: stereoselective synthesis of 2,6-disubstituted-3,4-dihydropyrans. The Journal of Organic Chemistry. 73: 5592-4. PMID 18570473 DOI: 10.1021/Jo800704D |
0.735 |
|
2007 |
Kartika R, Taylor RE. Electrophile-induced ether transfer: stereoselective synthesis of 2,4,6-trisubstituted tetrahydropyrans. Angewandte Chemie (International Ed. in English). 46: 6874-7. PMID 17674386 DOI: 10.1002/Anie.200702018 |
0.736 |
|
2007 |
Melancon BJ, Perl NR, Taylor RE. Competitive cationic pathways and the asymmetric synthesis of aryl-substituted cyclopropanes. Organic Letters. 9: 1425-8. PMID 17362019 DOI: 10.1021/Ol063026P |
0.397 |
|
2007 |
Kartika R, Taylor RE. Electrophile-induced ether transfer: An expedient route to 2-cyano-tetrahydropyrans Heterocycles. 74: 447-459. DOI: 10.3987/Com-07-S(W)23 |
0.706 |
|
2007 |
Tung JC, Chen W, Noll BC, Taylor RE, Fields SC, Dent WH, Green FR. Towards the synthesis of the cornexistins Synthesis. 2388-2396. DOI: 10.1055/S-2007-983769 |
0.637 |
|
2007 |
Daly EM, Taylor RE. Recent applications of the Nozaki-Hiyama-Kishi reaction in natural product synthesis Chemtracts. 20: 1-8. |
0.619 |
|
2007 |
Kartika R, Taylor RE. An exhaustive hydrogenation strategy to bicyclic alkaloids Chemtracts. 19: 385-390. |
0.617 |
|
2006 |
Liu K, Taylor RE, Kartika R. Electrophile-induced ether transfer: a new approach to polyketide structural units. Organic Letters. 8: 5393-5. PMID 17078726 DOI: 10.1021/Ol0623318 |
0.722 |
|
2006 |
Hines J, Roy M, Cheng H, Agapakis CM, Taylor R, Crews CM. Myriaporone 3/4 structure--activity relationship studies define a pharmacophore targeting eukaryotic protein synthesis. Molecular Biosystems. 2: 371-9. PMID 16880957 DOI: 10.1039/B602936A |
0.517 |
|
2005 |
Jin M, Taylor RE. Total synthesis of (+)-peloruside A. Organic Letters. 7: 1303-5. PMID 15787492 DOI: 10.1021/Ol050070G |
0.405 |
|
2005 |
Taylor RE, Fleming KN, Hearn BR. Chapter 8 Total synthesis of myriaporones 1, 3, and 4 Strategies and Tactics in Organic Synthesis. 6: 246-268. DOI: 10.1016/S1874-6004(05)80031-0 |
0.789 |
|
2005 |
Paquette WD, Taylor RE. Conformationally biased macrolactonizations Chemtracts. 18: 584-590. |
0.734 |
|
2004 |
Risatti CA, Taylor RE. Enantioselective synthesis of cyclopropanes by aldehyde homologation. Angewandte Chemie (International Ed. in English). 43: 6671-2. PMID 15593156 DOI: 10.1002/Anie.200461106 |
0.795 |
|
2004 |
Suckow MA, Gutierrez LS, Risatti CA, Wolter WR, Taylor RE, Pollard M, Navari RM, Castellino FJ, Paoni NF. The anti-ischemia agent ranolazine promotes the development of intestinal tumors in APC(Min/+) mice. Cancer Letters. 209: 165-9. PMID 15159018 DOI: 10.1016/J.Canlet.2004.01.007 |
0.726 |
|
2004 |
Fleming KN, Taylor RE. Total synthesis and stereochemical assignment of myriaporones 1, 3, and 4. Angewandte Chemie (International Ed. in English). 43: 1728-30. PMID 15038050 DOI: 10.1002/Anie.200353348 |
0.728 |
|
2004 |
Taylor RE, Chen Y, Galvin GM, Pabba PK. Conformation-activity relationships in polyketide natural products. Towards the biologically active conformation of epothilone. Organic & Biomolecular Chemistry. 2: 127-32. PMID 14737671 DOI: 10.1039/B312213C |
0.766 |
|
2004 |
Paquette WD, Taylor RE. Enantioselective preparation of the C1-C11 fragment of apoptolidin. Organic Letters. 6: 103-6. PMID 14703361 DOI: 10.1021/Ol0361397 |
0.791 |
|
2004 |
Risatti CA, Taylor RE. Biomimetic Synthesis of Polycyclic Natural Products from Acyclic Precursors Chemtracts. 17: 83-91. |
0.771 |
|
2003 |
Taylor RE, Jin M. Toward a total synthesis of peloruside A: enantioselective preparation of the C8-C19 region. Organic Letters. 5: 4959-61. PMID 14682739 DOI: 10.1021/Ol0358814 |
0.374 |
|
2003 |
Yoshimura F, Rivkin A, Gabarda AE, Chou TC, Dong H, Sukenick G, Morel FF, Taylor RE, Danishefsky SJ. Synthesis and conformational analysis of (E)-9,10-dehydroepothilone B: a suggestive link between the chemistry and biology of epothilones. Angewandte Chemie (International Ed. in English). 42: 2518-21. PMID 12800175 DOI: 10.1002/Anie.200351407 |
0.308 |
|
2003 |
Taylor RE, Risatti CA, Engelhardt FC, Schmitt MJ. Cyclopropane structural units from homoaldol adducts. Organic Letters. 5: 1377-9. PMID 12688763 DOI: 10.1021/Ol034448R |
0.773 |
|
2003 |
Taylor RE, Chen Y, Beatty A, Myles DC, Zhou Y. Conformation-activity relationships in polyketide natural products: a new perspective on the rational design of epothilone analogues. Journal of the American Chemical Society. 125: 26-7. PMID 12515494 DOI: 10.1021/Ja028196L |
0.324 |
|
2003 |
Taylor RE, Engelhardt FC, Schmitt MJ. Biosynthetic inspirations: Cationic approaches to cyclopropane formation Tetrahedron. 59: 5623-5634. DOI: 10.1016/S0040-4020(03)00880-9 |
0.723 |
|
2003 |
Brown AV, Taylor RE. Lewis acid induced epoxide rearrangement for complex molecule synthesis Chemtracts. 16: 254-258. |
0.593 |
|
2002 |
Taylor RE, Hearn BR, Ciavarri JP. A divergent approach to the myriaporones and tedanolide: completion of the carbon skeleton of myriaporone 1. Organic Letters. 4: 2953-5. PMID 12182597 DOI: 10.1021/Ol026356S |
0.772 |
|
2001 |
Taylor RE, Chen Y. Total synthesis of epothilones B and D Organic Letters. 3: 2221-2223. PMID 11440584 DOI: 10.1021/Ol010094X |
0.381 |
|
2001 |
Engelhardt FC, Schmitt MJ, Taylor RE. Kinetically controlled cross-metathesis reactions with high E-olefin selectivities. Organic Letters. 3: 2209-12. PMID 11440581 DOI: 10.1021/Ol016061Z |
0.702 |
|
2001 |
Taylor RE, Engelhardt FC, Schmitt MJ, Yuan H. Synthetic methodology for the construction of structurally diverse cyclopropanes Journal of the American Chemical Society. 123: 2964-2969. DOI: 10.1021/Ja0037163 |
0.7 |
|
2000 |
Taylor RE, Schmitt MJ, Yuan H. Structural diversity based on cyclopropane scaffolds Organic Letters. 2: 601-3. PMID 10814388 DOI: 10.1021/Ol9913542 |
0.5 |
|
1999 |
Taylor RE, Conrad Engelhardt F, Yuan H. Oligocyclopropane structural units from cationic intermediates Organic Letters. 1: 1257-1260. DOI: 10.1021/Ol990221D |
0.417 |
|
1999 |
Taylor RE, Zajicek J. Conformational properties of epothilone Journal of Organic Chemistry. 64: 7224-7228. DOI: 10.1021/Jo991014U |
0.319 |
|
1999 |
Taylor RE, Ciavarri JP. 2-bromoallyl acetate: A useful structural unit for sequential carbon-carbon bond formation Organic Letters. 1: 467-469. |
0.729 |
|
1998 |
Taylor RE, Galvin GM, Hilfiker KA, Chen Y. A formal total synthesis of epothilone A: Enantioselective preparation of the C1-C6 and C7-C12 fragments Journal of Organic Chemistry. 63: 9580-9583. DOI: 10.1021/Jo981461U |
0.811 |
|
1998 |
Taylor RE, Ciavarri JP, Hearn BR. A divergent approach to the myriaporones and tedanolide: Enantioselective preparation of the common intermediate Tetrahedron Letters. 39: 9361-9364. DOI: 10.1016/S0040-4039(98)02110-8 |
0.798 |
|
1998 |
Patterson S, Smith BD, Taylor RE. Tuning the affinity of a synthetic sialic acid receptor using combinatorial chemistry Tetrahedron Letters. 39: 3111-3114. DOI: 10.1016/S0040-4039(98)00514-0 |
0.448 |
|
1997 |
Wender PA, Badham NF, Conway SP, Floreancig PE, Glass TE, Houze JB, Krauss NE, Lee D, Marquess DG, McGrane PL, Meng W, Natchus MG, Shuker AJ, Sutton JC, Taylor RE. The pinene path to taxanes. 6. A concise stereocontrolled synthesis of taxol Journal of the American Chemical Society. 119: 2757-2758. DOI: 10.1021/Ja963539Z |
0.794 |
|
1997 |
Wender PA, Badham NF, Conway SP, Floreancig PE, Glass TE, Granicher C, Houze JB, Janichen J, Lee D, Marquess DG, McGrane PL, Meng W, Mucciaro TP, Muhlebach M, Natchus MG, ... ... Taylor RE, et al. The pinene path tot taxanes. 5. Stereocontrolled synthesis of a versatile taxane precursor Journal of the American Chemical Society. 119: 2755-2756. DOI: 10.1021/Ja9635387 |
0.792 |
|
1997 |
Patterson S, Smith BD, Taylor RE. Fluorescence sensing of a ribonucleoside 5'-triphosphate Tetrahedron Letters. 38: 6323-6326. DOI: 10.1016/S0040-4039(97)01454-8 |
0.423 |
|
1997 |
Taylor RE, Haley JD. Towards the synthesis of epothilone A: Enantioselective preparation of the thiazole side-chain and macrocyclic ring closure Tetrahedron Letters. 38: 2061-2064. DOI: 10.1016/S0040-4039(97)00285-2 |
0.412 |
|
1997 |
Taylor RE, Ameriks MK, LaMarche MJ. A novel approach to oligocyclopropane structural units Tetrahedron Letters. 38: 2057-2060. DOI: 10.1016/S0040-4039(97)00284-0 |
0.377 |
|
1992 |
Schultz AG, Taveras AG, Taylor RE, Tham FS, Kullnig RK. Solid-state photochemistry. Remarkable effects of the packing of molecules in crystals on the diastereoselectivity of the intramolecular 2 + 2 photocycloaddition of a 4- (3′-butenyl)-2,5-cyclohexadien-1-one Journal of the American Chemical Society. 114: 8725-8727. DOI: 10.1021/Ja00048A070 |
0.504 |
|
1992 |
Schultz AG, Taylor RE. Diastereoselective ester enolate alkylations. Asymmetric syntheses of 3-alkyl-3-carbomethoxy-2-exo-methylene-5-cyclohexen-1-ones. [Erratum to document cited in CA116(21):214030x] Journal of the American Chemical Society. 114: 8341-8341. DOI: 10.1021/Ja00047A084 |
0.544 |
|
1992 |
Schultz AG, Taylor RE. Diastereoselective ester enolate alkylations. Asymmetric syntheses of 3-alkyl-3-carbomethoxy-2-exo-methylenecyclohex-5-en-1-ones Journal of the American Chemical Society. 114: 3937-3943. DOI: 10.1021/Ja00036A047 |
0.552 |
|
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