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Martin A. Schwartz - Publications

Affiliations: 
Cell Biology Yale University School of Medicine, New Haven, CT 
Area:
Integrin signaling; mechanotransduction; atherosclerosis; vascular remodeling; heart disease; extracellular matrix; cell adhesion; cytoskeleton; cell-cell junctions; fluid shear stress
Website:
http://www.cellbiology.yale.edu/people/martin_schwartz.profile

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Yun S, Budatha M, Dahlman JE, Coon BG, Cameron RT, Langer R, Anderson DG, Baillie G, Schwartz MA. Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling. Nature Cell Biology. PMID 27595237 DOI: 10.1038/Ncb3405  1
2016 Gerhold KA, Schwartz MA. Ion Channels in Endothelial Responses to Fluid Shear Stress. Physiology (Bethesda, Md.). 31: 359-69. PMID 27511462 DOI: 10.1152/Physiol.00007.2016  1
2016 Kumar A, Ouyang M, Van den Dries K, McGhee EJ, Tanaka K, Anderson MD, Groisman A, Goult BT, Anderson KI, Schwartz MA. Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity. The Journal of Cell Biology. 213: 371-83. PMID 27161398 DOI: 10.1083/Jcb.201510012  1
2016 Baeyens N, Bandyopadhyay C, Coon BG, Yun S, Schwartz MA. Endothelial fluid shear stress sensing in vascular health and disease. The Journal of Clinical Investigation. 126: 821-8. PMID 26928035 DOI: 10.1172/Jci83083  1
2016 Baeyens N, Schwartz MA. Biomechanics of vascular mechanosensation and remodeling. Molecular Biology of the Cell. 27: 7-11. PMID 26715421 DOI: 10.1091/Mbc.E14-11-1522  1
2015 Coon BG, Baeyens N, Han J, Budatha M, Ross TD, Fang JS, Yun S, Thomas JL, Schwartz MA. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. The Journal of Cell Biology. 208: 975-86. PMID 25800053 DOI: 10.1085/Jgp.1454Oia13  1
2015 Tornavaca O, Chia M, Dufton N, Almagro LO, Conway DE, Randi AM, Schwartz MA, Matter K, Balda MS. ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation. The Journal of Cell Biology. 208: 821-38. PMID 25753039 DOI: 10.1083/Jcb.201404140  1
2015 Daneshjou N, Sieracki N, van Nieuw Amerongen GP, Schwartz MA, Komarova YA, Malik AB, Conway DE. Rac1 functions as a reversible tension modulator to stabilize VE-cadherin trans-interaction. The Journal of Cell Biology. 208: 23-32. PMID 25559184 DOI: 10.1083/Jcb.201409108  1
2015 Bancroft T, Bouaouina M, Roberts S, Lee M, Calderwood DA, Schwartz M, Simons M, Sessa WC, Kyriakides TR. Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function. The Journal of Biological Chemistry. 290: 409-22. PMID 25389299 DOI: 10.1074/Jbc.M114.618421  1
2015 Andarawewa KL, Moissoglu K, Sup Lee C, Ando Y, Yu M, Debnath P, Shannon JD, Sirinivasan S, Conaway MR, Weber MJ, Schwartz MA. Integrin adjunct therapy for melanoma. Pigment Cell & Melanoma Research. 28: 114-6. PMID 25264294 DOI: 10.1111/Pcmr.12320  1
2015 Mohamied Y, Rowland EM, Bailey EL, Sherwin SJ, Schwartz MA, Weinberg PD. Change of direction in the biomechanics of atherosclerosis. Annals of Biomedical Engineering. 43: 16-25. PMID 25138165 DOI: 10.1007/S10439-014-1095-4  1
2015 Daneshjou N, Sieracki N, Van Nieuw Amerongen GP, Conway DE, Schwartz MA, Komarova YA, Malik AB. Correction to Rac1 functions as a reversible tension modulator to stabilize VE-cadherin trans-interaction [Journal of Cell Biology, 208, 1, (2015) 23-32] Journal of Cell Biology. 209: 181.  1
2014 Moissoglu K, Schwartz MA. Spatial and temporal control of Rho GTPase functions. Cellular Logistics. 4: e943618. PMID 25610718 DOI: 10.4161/21592780.2014.943618  0.44
2014 Conway DE, Schwartz MA. Mechanotransduction of shear stress occurs through changes in VE-cadherin and PECAM-1 tension: Implications for cell migration. Cell Adhesion & Migration. 1-5. PMID 25482618 DOI: 10.4161/19336918.2014.968498  1
2014 Baeyens N, Mulligan-Kehoe MJ, Corti F, Simon DD, Ross TD, Rhodes JM, Wang TZ, Mejean CO, Simons M, Humphrey J, Schwartz MA. Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling. Proceedings of the National Academy of Sciences of the United States of America. 111: 17308-13. PMID 25404299 DOI: 10.1073/Pnas.1413725111  1
2014 Yan C, Liu D, Li L, Wempe MF, Guin S, Khanna M, Meier J, Hoffman B, Owens C, Wysoczynski CL, Nitz MD, Knabe WE, Ahmed M, Brautigan DL, Paschal BM, ... Schwartz MA, et al. Discovery and characterization of small molecules that target the GTPase Ral. Nature. 515: 443-7. PMID 25219851 DOI: 10.1038/Nature13713  1
2014 Morrison AR, Yarovinsky TO, Young BD, Moraes F, Ross TD, Ceneri N, Zhang J, Zhuang ZW, Sinusas AJ, Pardi R, Schwartz MA, Simons M, Bender JR. Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis. The Journal of Experimental Medicine. 211: 1957-68. PMID 25180062 DOI: 10.1084/Jem.20132130  1
2014 Leerberg JM, Gomez GA, Verma S, Moussa EJ, Wu SK, Priya R, Hoffman BD, Grashoff C, Schwartz MA, Yap AS. Tension-sensitive actin assembly supports contractility at the epithelial zonula adherens. Current Biology : Cb. 24: 1689-99. PMID 25065757 DOI: 10.1016/J.Cub.2014.06.028  1
2014 Schwartz M. Sticking to it: Tracking the paths of integrin signalling Nature Cell Biology. 16: 487. PMID 24875734 DOI: 10.1038/Ncb2971  1
2014 Humphrey JD, Milewicz DM, Tellides G, Schwartz MA. Cell biology. Dysfunctional mechanosensing in aneurysms. Science (New York, N.Y.). 344: 477-9. PMID 24786066 DOI: 10.1126/Science.1253026  1
2014 Moissoglu K, Kiessling V, Wan C, Hoffman BD, Norambuena A, Tamm LK, Schwartz MA. Regulation of Rac1 translocation and activation by membrane domains and their boundaries. Journal of Cell Science. 127: 2565-76. PMID 24695858 DOI: 10.1242/Jcs.149088  1
2013 Conway DE, Schwartz MA. Flow-dependent cellular mechanotransduction in atherosclerosis. Journal of Cell Science. 126: 5101-9. PMID 24190880 DOI: 10.1242/Jcs.138313  1
2013 Dufresne ER, Schwartz MA. Cell migration: Towards the void. Nature Materials. 12: 783-4. PMID 23966050 DOI: 10.1038/Nmat3743  1
2013 Wang C, Baker BM, Chen CS, Schwartz MA. Endothelial cell sensing of flow direction. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2130-6. PMID 23814115 DOI: 10.1161/Atvbaha.113.301826  1
2013 Ross TD, Coon BG, Yun S, Baeyens N, Tanaka K, Ouyang M, Schwartz MA. Integrins in mechanotransduction. Current Opinion in Cell Biology. 25: 613-8. PMID 23797029 DOI: 10.1016/J.Ceb.2013.05.006  1
2013 Conway DE, Breckenridge MT, Hinde E, Gratton E, Chen CS, Schwartz MA. Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Current Biology : Cb. 23: 1024-30. PMID 23684974 DOI: 10.1016/J.Cub.2013.04.049  1
2013 Jin Y, Roycik MD, Bosco DB, Cao Q, Constantino MH, Schwartz MA, Sang QX. Matrix metalloproteinase inhibitors based on the 3-mercaptopyrrolidine core. Journal of Medicinal Chemistry. 56: 4357-73. PMID 23631440 DOI: 10.1021/Jm400529F  1
2013 Ouyang M, Lu S, Kim T, Chen CE, Seong J, Leckband DE, Wang F, Reynolds AB, Schwartz MA, Wang Y. N-cadherin regulates spatially polarized signals through distinct p120ctn and β-catenin-dependent signalling pathways. Nature Communications. 4: 1589. PMID 23481397 DOI: 10.1038/Ncomms2560  1
2013 Schwartz MA, Chen CS. Cell biology. Deconstructing dimensionality. Science (New York, N.Y.). 339: 402-4. PMID 23349278 DOI: 10.1126/Science.1233814  1
2013 Park MH, Lee HS, Lee CS, You ST, Kim DJ, Park BH, Kang MJ, Heo WD, Shin EY, Schwartz MA, Kim EG. p21-Activated kinase 4 promotes prostate cancer progression through CREB. Oncogene. 32: 2475-82. PMID 22710715 DOI: 10.1038/onc.2012.255  1
2012 Tirziu D, Jaba IM, Yu P, Larrivée B, Coon BG, Cristofaro B, Zhuang ZW, Lanahan AA, Schwartz MA, Eichmann A, Simons M. Endothelial nuclear factor-κB-dependent regulation of arteriogenesis and branching. Circulation. 126: 2589-600. PMID 23091063 DOI: 10.1161/Circulationaha.112.119321  1
2012 Simons M, Schwartz MA. Profilin phosphorylation as a VEGFR effector in angiogenesis. Nature Cell Biology. 14: 985-7. PMID 23033049 DOI: 10.1038/Ncb2596  1
2012 Jhaveri KA, Debnath P, Chernoff J, Sanders J, Schwartz MA. The role of p21-activated kinase in the initiation of atherosclerosis. Bmc Cardiovascular Disorders. 12: 55. PMID 22824149 DOI: 10.1186/1471-2261-12-55  1
2012 Yaqoob U, Cao S, Shergill U, Jagavelu K, Geng Z, Yin M, De Assuncao TM, Cao Y, Szabolcs A, Thorgeirsson S, Schwartz M, Yang JD, Ehman R, Roberts L, Mukhopadhyay D, et al. Neuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironment Cancer Research. 72: 4047-4059. PMID 22738912 DOI: 10.1158/0008-5472.Can-11-3907  1
2012 Schwartz MA, Simons M. Lymphatics thrive on stress: mechanical force in lymphatic development. The Embo Journal. 31: 781-2. PMID 22334045 DOI: 10.1038/Emboj.2011.484  1
2012 Batra N, Burra S, Siller-Jackson AJ, Gu S, Xia X, Weber GF, DeSimone D, Bonewald LF, Lafer EM, Sprague E, Schwartz MA, Jiang JX. Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels. Proceedings of the National Academy of Sciences of the United States of America. 109: 3359-64. PMID 22331870 DOI: 10.1073/Pnas.1115967109  1
2012 Conway D, Schwartz MA. Lessons from the endothelial junctional mechanosensory complex. F1000 Biology Reports. 4: 1. PMID 22238515 DOI: 10.3410/B4-1  1
2011 Hahn C, Wang C, Orr AW, Coon BG, Schwartz MA. JNK2 promotes endothelial cell alignment under flow. Plos One. 6: e24338. PMID 21909388 DOI: 10.1371/Journal.Pone.0024338  1
2011 Norambuena A, Schwartz MA. Effects of integrin-mediated cell adhesion on plasma membrane lipid raft components and signaling. Molecular Biology of the Cell. 22: 3456-64. PMID 21795400 DOI: 10.1091/Mbc.E11-04-0361  1
2011 Hoffman BD, Grashoff C, Schwartz MA. Dynamic molecular processes mediate cellular mechanotransduction. Nature. 475: 316-23. PMID 21776077 DOI: 10.1038/Nature10316  1
2011 Goguen BN, Hoffman BD, Sellers JR, Schwartz MA, Imperiali B. Light-triggered myosin activation for probing dynamic cellular processes. Angewandte Chemie (International Ed. in English). 50: 5667-70. PMID 21542072 DOI: 10.1002/Anie.201100674  1
2011 Min D, Chen M, Zheng L, Jin Y, Schwartz MA, Sang QX, Yang W. Enhancing QM/MM molecular dynamics sampling in explicit environments via an orthogonal-space-random-walk-based strategy. The Journal of Physical Chemistry. B. 115: 3924-35. PMID 21417256 DOI: 10.1021/Jp109454Q  1
2011 Schwartz MA. Super-resolution microscopy: a new dimension in focal adhesions. Current Biology : Cb. 21: R115-6. PMID 21300274 DOI: 10.1016/J.Cub.2010.12.025  1
2011 Thomas S, Overdevest JB, Nitz MD, Williams PD, Owens CR, Sanchez-Carbayo M, Frierson HF, Schwartz MA, Theodorescu D. Src and caveolin-1 reciprocally regulate metastasis via a common downstream signaling pathway in bladder cancer. Cancer Research. 71: 832-41. PMID 21148751 DOI: 10.1158/0008-5472.Can-10-0730  1
2010 Schwartz MA. Integrins and extracellular matrix in mechanotransduction. Cold Spring Harbor Perspectives in Biology. 2: a005066. PMID 21084386 DOI: 10.1101/Cshperspect.A005066  1
2010 Parsons JT, Horwitz AR, Schwartz MA. Cell adhesion: integrating cytoskeletal dynamics and cellular tension. Nature Reviews. Molecular Cell Biology. 11: 633-43. PMID 20729930 DOI: 10.1038/Nrm2957  1
2010 Lee CS, Choi CK, Shin EY, Schwartz MA, Kim EG. Myosin II directly binds and inhibits Dbl family guanine nucleotide exchange factors: a possible link to Rho family GTPases. The Journal of Cell Biology. 190: 663-74. PMID 20713598 DOI: 10.1083/Jcb.201003057  1
2010 Shin ME, He Y, Li D, Na S, Chowdhury F, Poh YC, Collin O, Su P, de Lanerolle P, Schwartz MA, Wang N, Wang F. Spatiotemporal organization, regulation, and functions of tractions during neutrophil chemotaxis. Blood. 116: 3297-310. PMID 20616216 DOI: 10.1182/Blood-2009-12-260851  1
2010 Grashoff C, Hoffman BD, Brenner MD, Zhou R, Parsons M, Yang MT, McLean MA, Sligar SG, Chen CS, Ha T, Schwartz MA. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature. 466: 263-6. PMID 20613844 DOI: 10.1038/Nature09198  1
2010 Feaver RE, Gelfand BD, Wang C, Schwartz MA, Blackman BR. Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation. Circulation Research. 106: 1703-11. PMID 20378855 DOI: 10.1161/Circresaha.109.216283  1
2010 Funk SD, Yurdagul A, Green JM, Jhaveri KA, Schwartz MA, Orr AW. Matrix-specific protein kinase A signaling regulates p21-activated kinase activation by flow in endothelial cells. Circulation Research. 106: 1394-403. PMID 20224042 DOI: 10.1161/Circresaha.109.210286  1
2010 Schwartz MA. Remembrance of dead cells past: discovering that the extracellular matrix is a cell survival factor. Molecular Biology of the Cell. 21: 499-500. PMID 20150528 DOI: 10.1091/Mbc.E09-07-0602  1
2010 Balasubramanian N, Meier JA, Scott DW, Norambuena A, White MA, Schwartz MA. RalA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Current Biology : Cb. 20: 75-9. PMID 20005108 DOI: 10.1016/J.Cub.2009.11.016  1
2009 Petzold T, Orr AW, Hahn C, Jhaveri KA, Parsons JT, Schwartz MA. Focal adhesion kinase modulates activation of NF-kappaB by flow in endothelial cells. American Journal of Physiology. Cell Physiology. 297: C814-22. PMID 19587216 DOI: 10.1152/Ajpcell.00226.2009  1
2009 Elfenbein A, Rhodes JM, Meller J, Schwartz MA, Matsuda M, Simons M. Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway. The Journal of Cell Biology. 186: 75-83. PMID 19581409 DOI: 10.1083/Jcb.200810179  1
2009 Wu Y, Moissoglu K, Wang H, Wang X, Frierson HF, Schwartz MA, Theodorescu D. Src phosphorylation of RhoGDI2 regulates its metastasis suppressor function. Proceedings of the National Academy of Sciences of the United States of America. 106: 5807-12. PMID 19321744 DOI: 10.1073/Pnas.0810094106  1
2009 Dzamba BJ, Jakab KR, Marsden M, Schwartz MA, DeSimone DW. Cadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization. Developmental Cell. 16: 421-32. PMID 19289087 DOI: 10.1016/J.Devcel.2009.01.008  1
2009 Hahn C, Orr AW, Sanders JM, Jhaveri KA, Schwartz MA. The subendothelial extracellular matrix modulates JNK activation by flow. Circulation Research. 104: 995-1003. PMID 19286608 DOI: 10.1161/Circresaha.108.186486  1
2009 Moissoglu K, McRoberts KS, Meier JA, Theodorescu D, Schwartz MA. Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. Cancer Research. 69: 2838-44. PMID 19276387 DOI: 10.1158/0008-5472.Can-08-1397  1
2009 Hahn C, Schwartz MA. Mechanotransduction in vascular physiology and atherogenesis. Nature Reviews. Molecular Cell Biology. 10: 53-62. PMID 19197332 DOI: 10.1038/Nrm2596  1
2009 Schwartz MA. Cell biology. The force is with us. Science (New York, N.Y.). 323: 588-9. PMID 19179515 DOI: 10.1126/Science.1169414  1
2009 Sebbagh M, Santoni MJ, Hall B, Borg JP, Schwartz MA. Regulation of LKB1/STRAD localization and function by E-cadherin. Current Biology : Cb. 19: 37-42. PMID 19110428 DOI: 10.1016/J.Cub.2008.11.033  1
2008 Schwartz MA, McRoberts K, Coyner M, Andarawewa KL, Frierson HF, Sanders JM, Swenson S, Markland F, Conaway MR, Theodorescu D. Integrin agonists as adjuvants in chemotherapy for melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 6193-7. PMID 18829498 DOI: 10.1158/1078-0432.Ccr-08-1285  1
2008 Hahn C, Schwartz MA. The role of cellular adaptation to mechanical forces in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2101-7. PMID 18787190 DOI: 10.1161/Atvbaha.108.165951  1
2008 Harry BL, Sanders JM, Feaver RE, Lansey M, Deem TL, Zarbock A, Bruce AC, Pryor AW, Gelfand BD, Blackman BR, Schwartz MA, Ley K. Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2003-8. PMID 18688018 DOI: 10.1161/Atvbaha.108.164707  1
2008 Orr AW, Hahn C, Blackman BR, Schwartz MA. p21-activated kinase signaling regulates oxidant-dependent NF-kappa B activation by flow. Circulation Research. 103: 671-9. PMID 18669917 DOI: 10.1161/Circresaha.108.182097  1
2008 Schwartz MA, DeSimone DW. Cell adhesion receptors in mechanotransduction. Current Opinion in Cell Biology. 20: 551-6. PMID 18583124 DOI: 10.1016/J.Ceb.2008.05.005  1
2008 Meller J, Vidali L, Schwartz MA. Endogenous RhoG is dispensable for integrin-mediated cell spreading but contributes to Rac-independent migration. Journal of Cell Science. 121: 1981-9. PMID 18505794 DOI: 10.1242/Jcs.025130  1
2008 Schwartz MA. The importance of stupidity in scientific research. Journal of Cell Science. 121: 1771. PMID 18492790 DOI: 10.1785/Gssrl.82.1.3  1
2008 Hall B, McLean MA, Davis K, Casanova JE, Sligar SG, Schwartz MA. A fluorescence resonance energy transfer activation sensor for Arf6. Analytical Biochemistry. 374: 243-9. PMID 18162163 DOI: 10.1016/J.Ab.2007.11.032  1
2008 Meller N, Westbrook MJ, Shannon JD, Guda C, Schwartz MA. Function of the N-terminus of zizimin1: autoinhibition and membrane targeting. The Biochemical Journal. 409: 525-33. PMID 17935486 DOI: 10.1042/Bj20071263  1
2007 Balasubramanian N, Scott DW, Castle JD, Casanova JE, Schwartz MA. Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts. Nature Cell Biology. 9: 1381-91. PMID 18026091 DOI: 10.1038/Ncb1657  1
2007 Stockton R, Reutershan J, Scott D, Sanders J, Ley K, Schwartz MA. Induction of vascular permeability: beta PIX and GIT1 scaffold the activation of extracellular signal-regulated kinase by PAK. Molecular Biology of the Cell. 18: 2346-55. PMID 17429073 DOI: 10.1091/Mbc.E06-07-0584  1
2007 Del Pozo MA, Schwartz MA. Rac, membrane heterogeneity, caveolin and regulation of growth by integrins. Trends in Cell Biology. 17: 246-50. PMID 17363257 DOI: 10.1016/J.Tcb.2007.03.001  1
2007 Reutershan J, Stockton R, Zarbock A, Sullivan GW, Chang D, Scott D, Schwartz MA, Ley K. Blocking p21-activated kinase reduces lipopolysaccharide-induced acute lung injury by preventing polymorphonuclear leukocyte infiltration. American Journal of Respiratory and Critical Care Medicine. 175: 1027-35. PMID 17322107 DOI: 10.1164/Rccm.200612-1822Oc  1
2007 Orr AW, Stockton R, Simmers MB, Sanders JM, Sarembock IJ, Blackman BR, Schwartz MA. Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis. The Journal of Cell Biology. 176: 719-27. PMID 17312022 DOI: 10.1083/Jcb.200609008  1
2006 Lechene C, Hillion F, McMahon G, Benson D, Kleinfeld AM, Kampf JP, Distel D, Luyten Y, Bonventre J, Hentschel D, Park KM, Ito S, Schwartz M, Benichou G, Slodzian G. High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry. Journal of Biology. 5: 20. PMID 17010211 DOI: 10.1186/Jbiol42  1
2006 Gaus K, Le Lay S, Balasubramanian N, Schwartz MA. Integrin-mediated adhesion regulates membrane order. The Journal of Cell Biology. 174: 725-34. PMID 16943184 DOI: 10.1083/Jcb.200603034  1
2006 Orr AW, Ginsberg MH, Shattil SJ, Deckmyn H, Schwartz MA. Matrix-specific suppression of integrin activation in shear stress signaling. Molecular Biology of the Cell. 17: 4686-97. PMID 16928957 DOI: 10.1091/Mbc.E06-04-0289  1
2006 Moissoglu K, Schwartz MA. Integrin signalling in directed cell migration Biology of the Cell. 98: 547-555. PMID 16907663 DOI: 10.1042/Bc20060025  1
2006 Schwartz MA, Horwitz AR. Integrating adhesion, protrusion, and contraction during cell migration. Cell. 125: 1223-5. PMID 16814706 DOI: 10.1016/J.Cell.2006.06.015  1
2006 Sang QX, Jin Y, Newcomer RG, Monroe SC, Fang X, Hurst DR, Lee S, Cao Q, Schwartz MA. Matrix metalloproteinase inhibitors as prospective agents for the prevention and treatment of cardiovascular and neoplastic diseases. Current Topics in Medicinal Chemistry. 6: 289-316. PMID 16611144 DOI: 10.2174/156802606776287045  1
2006 Moissoglu K, Slepchenko BM, Meller N, Horwitz AF, Schwartz MA. In vivo dynamics of Rac-membrane interactions. Molecular Biology of the Cell. 17: 2770-9. PMID 16597700 DOI: 10.1091/Mbc.E06-01-0005  1
2006 Orr AW, Helmke BP, Blackman BR, Schwartz MA. Mechanisms of mechanotransduction. Developmental Cell. 10: 11-20. PMID 16399074 DOI: 10.1016/J.Devcel.2005.12.006  1
2006 Schwartz MA, Yap AS. Cell-to-cell contact and extracellular matrix Current Opinion in Cell Biology. 18: 461-462. DOI: 10.1016/J.Ceb.2006.08.013  1
2005 de Rooij J, Kerstens A, Danuser G, Schwartz MA, Waterman-Storer CM. Integrin-dependent actomyosin contraction regulates epithelial cell scattering. The Journal of Cell Biology. 171: 153-64. PMID 16216928 DOI: 10.1083/Jcb.200506152  1
2005 Bolick DT, Orr AW, Whetzel A, Srinivasan S, Hatley ME, Schwartz MA, Hedrick CC. 12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 2301-7. PMID 16166569 DOI: 10.1161/01.Atv.0000186181.19909.A6  1
2005 Tzima E, Irani-Tehrani M, Kiosses WB, Dejana E, Schultz DA, Engelhardt B, Cao G, DeLisser H, Schwartz MA. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature. 437: 426-31. PMID 16163360 DOI: 10.1038/Nature03952  1
2005 del Pozo MA, Balasubramanian N, Alderson NB, Kiosses WB, Grande-García A, Anderson RG, Schwartz MA. Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization. Nature Cell Biology. 7: 901-8. PMID 16113676 DOI: 10.1038/Ncb1293  1
2005 Hurst DR, Schwartz MA, Jin Y, Ghaffari MA, Kozarekar P, Cao J, Sang QX. Inhibition of enzyme activity of and cell-mediated substrate cleavage by membrane type 1 matrix metalloproteinase by newly developed mercaptosulphide inhibitors. The Biochemical Journal. 392: 527-36. PMID 16026329 DOI: 10.1042/Bj20050545  1
2005 Titus B, Schwartz MA, Theodorescu D. Rho proteins in cell migration and metastasis. Critical Reviews in Eukaryotic Gene Expression. 15: 103-14. PMID 16022631 DOI: 10.1615/Critreveukaryotgeneexpr.V15.I2.20  1
2005 Orr AW, Sanders JM, Bevard M, Coleman E, Sarembock IJ, Schwartz MA. The subendothelial extracellular matrix modulates NF-kappaB activation by flow: a potential role in atherosclerosis. The Journal of Cell Biology. 169: 191-202. PMID 15809308 DOI: 10.1083/Jcb.200410073  1
2005 Katsumi A, Naoe T, Matsushita T, Kaibuchi K, Schwartz MA. Integrin activation and matrix binding mediate cellular responses to mechanical stretch. The Journal of Biological Chemistry. 280: 16546-9. PMID 15760908 DOI: 10.1074/Jbc.C400455200  1
2005 Nishikimi A, Meller N, Uekawa N, Isobe K, Schwartz MA, Maruyama M. Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes. Febs Letters. 579: 1039-46. PMID 15710388 DOI: 10.1016/J.Febslet.2005.01.006  1
2005 Civelekoglu-Scholey G, Orr AW, Novak I, Meister JJ, Schwartz MA, Mogilner A. Model of coupled transient changes of Rac, Rho, adhesions and stress fibers alignment in endothelial cells responding to shear stress. Journal of Theoretical Biology. 232: 569-85. PMID 15588637 DOI: 10.1016/J.Jtbi.2004.09.004  1
2005 Tzima E, Reader JS, Irani-Tehrani M, Ewalt KL, Schwartz MA, Schimmel P. VE-cadherin links tRNA synthetase cytokine to anti-angiogenic function. The Journal of Biological Chemistry. 280: 2405-8. PMID 15579907 DOI: 10.1074/Jbc.C400431200  1
2004 Schwartz M. Rho signalling at a glance Journal of Cell Science. 117: 5457-5458. PMID 15509861 DOI: 10.1242/Jcs.01582  1
2004 Stockton RA, Schaefer E, Schwartz MA. p21-activated kinase regulates endothelial permeability through modulation of contractility. The Journal of Biological Chemistry. 279: 46621-30. PMID 15333633 DOI: 10.1074/Jbc.M408877200  1
2004 Meller N, Irani-Tehrani M, Ratnikov BI, Paschal BM, Schwartz MA. The novel Cdc42 guanine nucleotide exchange factor, zizimin1, dimerizes via the Cdc42-binding CZH2 domain. The Journal of Biological Chemistry. 279: 37470-6. PMID 15247287 DOI: 10.1074/Jbc.M404535200  1
2004 Helmke BP, Schwartz MA. Putting the squeeze on mechanotransduction. Developmental Cell. 6: 745-6. PMID 15177022 DOI: 10.1016/J.Devcel.2004.05.013  1
2004 Shiu YT, Li S, Marganski WA, Usami S, Schwartz MA, Wang YL, Dembo M, Chien S. Rho mediates the shear-enhancement of endothelial cell migration and traction force generation. Biophysical Journal. 86: 2558-65. PMID 15041692 DOI: 10.1016/S0006-3495(04)74311-8  1
2004 Katsumi A, Orr AW, Tzima E, Schwartz MA. Integrins in mechanotransduction. The Journal of Biological Chemistry. 279: 12001-4. PMID 14960578 DOI: 10.1074/Jbc.R300038200  1
2004 del Pozo MA, Alderson NB, Kiosses WB, Chiang HH, Anderson RG, Schwartz MA. Integrins regulate Rac targeting by internalization of membrane domains. Science (New York, N.Y.). 303: 839-42. PMID 14764880 DOI: 10.1126/Science.1092571  1
2004 Hurst DR, Schwartz MA, Ghaffari MA, Jin Y, Tschesche H, Fields GB, Sang QX. Catalytic- and ecto-domains of membrane type 1-matrix metalloproteinase have similar inhibition profiles but distinct endopeptidase activities. The Biochemical Journal. 377: 775-9. PMID 14533979 DOI: 10.1042/Bj20031067  1
2003 Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. Cell migration: integrating signals from front to back. Science (New York, N.Y.). 302: 1704-9. PMID 14657486 DOI: 10.1126/Science.1092053  1
2003 Park HI, Jin Y, Hurst DR, Monroe CA, Lee S, Schwartz MA, Sang QX. The intermediate S1' pocket of the endometase/matrilysin-2 active site revealed by enzyme inhibition kinetic studies, protein sequence analyses, and homology modeling. The Journal of Biological Chemistry. 278: 51646-53. PMID 14532275 DOI: 10.1074/Jbc.M310109200  1
2002 Schwartz MA. Matrix and meaning. Methods in Cell Biology. 69: 13-6. PMID 12070989 DOI: 10.1016/S0091-679X(02)69004-1  1
2002 Schwartz MA, Ginsberg MH. Networks and crosstalk: integrin signalling spreads. Nature Cell Biology. 4: E65-8. PMID 11944032 DOI: 10.1038/Ncb0402-E65  1
2002 Liu S, Kiosses WB, Rose DM, Slepak M, Salgia R, Griffin JD, Turner CE, Schwartz MA, Ginsberg MH. A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration. The Journal of Biological Chemistry. 277: 20887-94. PMID 11919182 DOI: 10.1074/Jbc.M110928200  0.32
1992 Schwartz MA, Van Wart HE. 8 Synthetic Inhibitors of Bacterial and Mammalian Interstitial Collagenases Progress in Medicinal Chemistry. 29: 271-334. DOI: 10.1016/S0079-6468(08)70011-0  1
1982 Lahav J, Schwartz MA, Hynes RO. Analysis of platelet adhesion with a radioactive chemical crosslinking reagent: interaction of thrombospondin with fibronectin and collagen. Cell. 31: 253-62. PMID 7159924 DOI: 10.1016/0092-8674(82)90425-1  0.36
1982 Schwartz MA, Das OP, Hynes RO. A new radioactive cross-linking reagent for studying the interactions of proteins. The Journal of Biological Chemistry. 257: 2343-9. PMID 7061425  1
1978 Schwartz MA, McConnell HM. Surface areas of lipid membranes. Biochemistry. 17: 837-40. PMID 629935 DOI: 10.1021/Bi00598A014  0.96
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