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Mathias G. Lichtenheld - Publications

Affiliations: 
University of Miami, Coral Gables, FL 
Area:
Immunology, Molecular Biology
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27/36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Bai F, McCormack RM, Hower S, Plano GV, Lichtenheld MG, Munson GP. Perforin-2 Breaches the Envelope of Phagocytosed Bacteria Allowing Antimicrobial Effectors Access to Intracellular Targets. Journal of Immunology (Baltimore, Md. : 1950). PMID 30249808 DOI: 10.4049/Jimmunol.1800365  0.318
2015 McCormack RM, de Armas LR, Shiratsuchi M, Fiorentino DG, Olsson ML, Lichtenheld MG, Morales A, Lyapichev K, Gonzalez LE, Strbo N, Sukumar N, Stojadinovic O, Plano GV, Munson GP, Tomic-Canic M, et al. Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria. Elife. 4. PMID 26402460 DOI: 10.7554/Elife.06508  0.346
2013 Díaz-Montero CM, Zidan AA, Pallin MF, Anagnostopoulos V, Salem ML, Wieder E, Komanduri K, Montero AJ, Lichtenheld MG. Understanding the biology of ex vivo-expanded CD8 T cells for adoptive cell therapy: role of CD62L. Immunologic Research. 57: 23-33. PMID 24218360 DOI: 10.1007/S12026-013-8456-1  0.416
2013 Lee JH, Wittki S, Bräu T, Dreyer FS, Krätzel K, Dindorf J, Johnston IC, Gross S, Kremmer E, Zeidler R, Schlötzer-Schrehardt U, Lichtenheld M, Saksela K, Harrer T, Schuler G, et al. HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases. Molecular Cell. 49: 668-79. PMID 23317503 DOI: 10.1016/J.Molcel.2012.12.004  0.33
2011 Parmigiani A, Pallin MF, Schmidtmayerova H, Lichtenheld MG, Pahwa S. Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antiviral activity in human CD8 T cells. Human Immunology. 72: 115-23. PMID 20977918 DOI: 10.1016/J.Humimm.2010.10.015  0.429
2010 Pipkin ME, Rao A, Lichtenheld MG. The transcriptional control of the perforin locus. Immunological Reviews. 235: 55-72. PMID 20536555 DOI: 10.1111/J.0105-2896.2010.00905.X  0.712
2010 Pipkin ME, Sacks JA, Cruz-Guilloty F, Lichtenheld MG, Bevan MJ, Rao A. Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells. Immunity. 32: 79-90. PMID 20096607 DOI: 10.1016/J.Immuni.2009.11.012  0.659
2009 Cruz-Guilloty F, Pipkin ME, Djuretic IM, Levanon D, Lotem J, Lichtenheld MG, Groner Y, Rao A. Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs. The Journal of Experimental Medicine. 206: 51-9. PMID 19139168 DOI: 10.1084/Jem.20081242  0.688
2008 Wolf D, Witte V, Clark P, Blume K, Lichtenheld MG, Baur AS. HIV Nef enhances Tat-mediated viral transcription through a hnRNP-K-nucleated signaling complex. Cell Host & Microbe. 4: 398-408. PMID 18854243 DOI: 10.1016/J.Chom.2008.08.013  0.31
2008 Strbo N, de Armas L, Liu H, Kolber MA, Lichtenheld M, Pahwa S. IL-21 augments natural killer effector functions in chronically HIV-infected individuals. Aids (London, England). 22: 1551-60. PMID 18670213 DOI: 10.1097/Qad.0B013E3283089367  0.315
2007 Rose S, Lichtenheld M, Foote MR, Adkins B. Murine neonatal CD4+ cells are poised for rapid Th2 effector-like function. Journal of Immunology (Baltimore, Md. : 1950). 178: 2667-78. PMID 17312108 DOI: 10.4049/Jimmunol.178.5.2667  0.432
2007 Pipkin ME, Ljutic B, Cruz-Guilloty F, Nouzova M, Rao A, Zúñiga-Pflücker JC, Lichtenheld MG. Chromosome transfer activates and delineates a locus control region for perforin. Immunity. 26: 29-41. PMID 17222571 DOI: 10.1016/J.Immuni.2006.11.009  0.685
2007 White L, Krishnan S, Strbo N, Liu H, Kolber MA, Lichtenheld MG, Pahwa RN, Pahwa S. Differential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV). Blood. 109: 3873-80. PMID 17192392 DOI: 10.1182/Blood-2006-09-045278  0.444
2006 Pipkin ME, Lichtenheld MG. A reliable method to display authentic DNase I hypersensitive sites at long-ranges in single-copy genes from large genomes. Nucleic Acids Research. 34: e34. PMID 16510851 DOI: 10.1093/Nar/Gkl006  0.643
2005 Buzzeo R, Enkemann S, Nimmanapalli R, Alsina M, Lichtenheld MG, Dalton WS, Beaupre DM. Characterization of a R115777-resistant human multiple myeloma cell line with cross-resistance to PS-341. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 6057-64. PMID 16115951 DOI: 10.1182/Blood.V104.11.3363.3363  0.3
2003 Beaupre DM, McCafferty-Grad J, Bahlis NJ, Boise LH, Lichtenheld MG. Farnesyl transferase inhibitors enhance death receptor signals and induce apoptosis in multiple myeloma cells. Leukemia & Lymphoma. 44: 2123-34. PMID 14959858 DOI: 10.1080/1042819031000116652  0.313
2003 Lu Q, Wu A, Ray D, Deng C, Attwood J, Hanash S, Pipkin M, Lichtenheld M, Richardson B. DNA methylation and chromatin structure regulate T cell perforin gene expression. Journal of Immunology (Baltimore, Md. : 1950). 170: 5124-32. PMID 12734359 DOI: 10.4049/Jimmunol.170.10.5124  0.678
2002 Zhou J, Zhang J, Lichtenheld MG, Meadows GG. A role for NF-kappa B activation in perforin expression of NK cells upon IL-2 receptor signaling. Journal of Immunology (Baltimore, Md. : 1950). 169: 1319-25. PMID 12133954 DOI: 10.4049/Jimmunol.169.3.1319  0.441
2001 Malek TR, Yu A, Scibelli P, Lichtenheld MG, Codias EK. Broad programming by IL-2 receptor signaling for extended growth to multiple cytokines and functional maturation of antigen-activated T cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 1675-83. PMID 11160210 DOI: 10.4049/Jimmunol.166.3.1675  0.436
1999 Zhang J, Scordi I, Smyth MJ, Lichtenheld MG. Interleukin 2 receptor signaling regulates the perforin gene through signal transducer and activator of transcription (Stat)5 activation of two enhancers Journal of Experimental Medicine. 190: 1297-1307. PMID 10544201 DOI: 10.1084/Jem.190.9.1297  0.478
1998 Cepero E, Hnatyszyn HJ, Kraus G, Lichtenheld MG. Potent inhibition of CTLA-4 expression by an anti-CTLA-4 ribozyme. Biochemical and Biophysical Research Communications. 247: 838-43. PMID 9647780 DOI: 10.1006/Bbrc.1998.8889  0.413
1991 Podack ER, Hengartner H, Lichtenheld MG. A central role of perforin in cytolysis? Annual Review of Immunology. 9: 129-57. PMID 1910674 DOI: 10.1146/Annurev.Iy.09.040191.001021  0.487
1990 Podack ER, Lichtenheld MG. Chapter 14 Perforin and the Mechanism of Lymphocyte-Mediated Cytolysis Current Topics in Membranes and Transport. 36: 161-175. DOI: 10.1016/S0070-2161(08)60176-8  0.387
1989 Lowrey DM, Aebischer T, Olsen K, Lichtenheld M, Rupp F, Hengartner H, Podack ER. Cloning, analysis, and expression of murine perforin 1 cDNA, a component of cytolytic T-cell granules with homology to complement component C9. Proceedings of the National Academy of Sciences of the United States of America. 86: 247-51. PMID 2783486 DOI: 10.1073/Pnas.86.1.247  0.356
1988 Lichtenheld MG, Olsen KJ, Lu P, Lowrey DM, Hameed A, Hengartner H, Podack ER. Structure and function of human perforin Nature. 335: 448-451. PMID 3419519 DOI: 10.1038/335448A0  0.308
1988 Podack ER, Lowrey DM, Lichtenheld M, Olsen KJ, Aebischer T, Binder D, Rupp F, Hengartner H. Structure, function and expression of murine and human perforin 1 (P1). Immunological Reviews. 103: 203-11. PMID 3292394 DOI: 10.1111/J.1600-065X.1988.Tb00756.X  0.301
1988 Podack ER, Lowrey DM, Lichtenheld M, Hameed A. Function of granule perforin and esterases in T cell-mediated reactions. Components required for delivery of molecules to target cells. Annals of the New York Academy of Sciences. 532: 292-302. PMID 2972243 DOI: 10.1111/J.1749-6632.1988.Tb36347.X  0.308
Low-probability matches (unlikely to be authored by this person)
2011 Díaz-Montero CM, Naga O, Zidan AA, Salem ML, Pallin M, Parmigiani A, Walker G, Wieder E, Komanduri K, Cole DJ, Montero AJ, Lichtenheld MG. Synergy of brief activation of CD8 T-cells in the presence of IL-12 and adoptive transfer into lymphopenic hosts promotes tumor clearance and anti-tumor memory. American Journal of Cancer Research. 1: 882-96. PMID 21915391  0.287
1989 Hameed A, Olsen KJ, Lee MK, Lichtenheld MG, Podack ER. Cytolysis by Ca-permeable transmembrane channels. Pore formation causes extensive DNA degradation and cell lysis Journal of Experimental Medicine. 169: 765-777. PMID 2538546 DOI: 10.1084/Jem.169.3.765  0.287
1989 Podack ER, Olsen KJ, Lowrey DM, Lichtenheld M. Structure and function of perforin Current Topics in Microbiology and Immunology. 140: 11-17. PMID 2644072 DOI: 10.1007/978-3-642-73911-8_2  0.285
2015 McCormack RM, Armas LRd, Shiratsuchi M, Fiorentino DG, Olsson ML, Lichtenheld MG, Morales A, Lyapichev K, Gonzalez LE, Strbo N, Sukumar N, Stojadinovic O, Plano GV, Munson GP, Tomic-Canic M, et al. Author response: Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria Elife. DOI: 10.7554/Elife.06508.037  0.28
2005 Zhu K, Gerbino E, Beaupre DM, Mackley PA, Muro-Cacho C, Beam C, Hamilton AD, Lichtenheld MG, Kerr WG, Dalton W, Alsina M, Sebti SM. Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells. Blood. 105: 4759-66. PMID 15728126 DOI: 10.1182/Blood-2004-11-4307  0.264
1991 Clément MV, Haddad P, Soulié A, Benvenuti C, Lichtenheld MG, Podack ER, Sigaux N, Sasportes M. Perforin and granzyme B as markers for acute rejection in heart transplantation. International Immunology. 3: 1175-81. PMID 1760412 DOI: 10.1016/0198-8859(91)90223-V  0.244
2004 Beaupre DM, Cepero E, Obeng EA, Boise LH, Lichtenheld MG. R115777 induces Ras-independent apoptosis of myeloma cells via multiple intrinsic pathways. Molecular Cancer Therapeutics. 3: 179-86. PMID 14985458  0.145
1991 Clément M, Haddad P, Soulié A, Benevenuti C, Lichtenheld M, Podack E, Sigaux N, Sasportes M. Perforin and granzyme B as markers for acute rejection in heart transplantation Human Immunology. 32: 60. DOI: 10.1016/0198-8859(91)90223-V  0.041
2020 van Zuilen MH, England JS, Sussman DA, Deshpande AR, Mechaber AJ, Issenberg SB, Lichtenheld MG. The Fallacy of Teaching and the Illusion of Learning: Improving Articulation of Basic Science in the Medical School Curriculum. Medical Science Educator. 30: 1735-1736. PMID 34457838 DOI: 10.1007/s40670-020-01075-z  0.011
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