Year |
Citation |
Score |
2021 |
Staquicini FI, Hajitou A, Driessen WH, Proneth B, Cardó-Vila M, Staquicini DI, Markosian C, Hoh M, Cortez M, Hooda-Nehra A, Jaloudi M, Silva IT, Buttura J, Nunes D, Dias-Neto E, ... ... Pasqualini R, et al. Targeting a cell surface vitamin D receptor on tumor-associated macrophages in triple-negative breast cancer. Elife. 10. PMID 34060472 DOI: 10.7554/eLife.65145 |
0.357 |
|
2020 |
Tang FHF, Davis D, Arap W, Pasqualini R, Staquicini FI. Eph receptors as cancer targets for antibody-based therapy. Advances in Cancer Research. 147: 303-317. PMID 32593404 DOI: 10.1016/bs.acr.2020.04.007 |
0.327 |
|
2019 |
Suwan K, Yata T, Waramit S, Przystal JM, Stoneham CA, Bentayebi K, Asavarut P, Chongchai A, Pothachareon P, Lee KY, Topanurak S, Smith TL, Gelovani JG, Sidman RL, Pasqualini R, et al. Next-generation of targeted AAVP vectors for systemic transgene delivery against cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 31375630 DOI: 10.1073/pnas.1906653116 |
0.327 |
|
2019 |
Staquicini FI, Smith TL, Tang FHF, Gelovani JG, Giordano RJ, Libutti SK, Sidman RL, Cavenee WK, Arap W, Pasqualini R. Targeted AAVP-based therapy in a mouse model of human glioblastoma: a comparison of cytotoxic versus suicide gene delivery strategies. Cancer Gene Therapy. PMID 31130731 DOI: 10.1038/s41417-019-0101-2 |
0.378 |
|
2019 |
Tang FHF, Staquicini FI, Teixeira AAR, Michaloski JS, Namiyama GM, Taniwaki NN, Setubal JC, da Silva AM, Sidman RL, Pasqualini R, Arap W, Giordano RJ. A ligand motif enables differential vascular targeting of endothelial junctions between brain and retina. Proceedings of the National Academy of Sciences of the United States of America. PMID 30670660 DOI: 10.1073/pnas.1809483116 |
0.308 |
|
2018 |
D'Angelo S, Staquicini FI, Ferrara F, Staquicini DI, Sharma G, Tarleton CA, Nguyen H, Naranjo LA, Sidman RL, Arap W, Bradbury AR, Pasqualini R. Selection of phage-displayed accessible recombinant targeted antibodies (SPARTA): methodology and applications. Jci Insight. 3. PMID 29720567 DOI: 10.1172/jci.insight.98305 |
0.303 |
|
2017 |
Staquicini DI, D'Angelo S, Ferrara F, Karjalainen K, Sharma G, Smith TL, Tarleton CA, Jaalouk DE, Kuniyasu A, Baze WB, Chaffee BK, Hanley PW, Barnhart KF, Koivunen E, Marchiò S, ... ... Pasqualini R, et al. Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates. The Pharmacogenomics Journal. PMID 29205207 DOI: 10.1038/Tpj.2017.46 |
0.362 |
|
2017 |
Al-Hashimi AA, Lebeau P, Majeed F, Polena E, Lhotak Š, Collins CAF, Pinthus JH, Gonzalez-Gronow M, Hoogenes J, Pizzo SV, Crowther M, Kapoor A, Rak J, Gyulay G, D'Angelo S, ... ... Pasqualini R, et al. Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor. The Journal of Biological Chemistry. PMID 29066620 DOI: 10.1074/Jbc.M117.799908 |
0.443 |
|
2017 |
Teixeira AA, Marchiò S, Dias-Neto E, Nunes DN, da Silva IT, Chackerian B, Barry M, Lauer RC, Giordano RJ, Sidman RL, Wheeler CM, Cavenee WK, Pasqualini R, Arap W. Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses. Embo Molecular Medicine. PMID 28751581 DOI: 10.15252/Emmm.201708072 |
0.321 |
|
2017 |
Lewis VO, Devarajan E, Cardó-Vila M, Thomas DG, Kleinerman ES, Marchiò S, Sidman RL, Pasqualini R, Arap W. BMTP-11 is active in preclinical models of human osteosarcoma and a candidate targeted drug for clinical translation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28698375 DOI: 10.1073/Pnas.1704173114 |
0.38 |
|
2017 |
Staquicini DI, Rangel R, Guzman-Rojas L, Staquicini FI, Dobroff AS, Tarleton CA, Ozbun MA, Kolonin MG, Gelovani JG, Marchiò S, Sidman RL, Hajjar KA, Arap W, Pasqualini R. Intracellular targeting of annexin A2 inhibits tumor cell adhesion, migration, and in vivo grafting. Scientific Reports. 7: 4243. PMID 28652618 DOI: 10.1038/S41598-017-03470-W |
0.436 |
|
2017 |
Smith TL, Souza GR, Sidman RL, Arap W, Pasqualini R. An AAVP-based solid-phase transducing matrix for transgene delivery: potential for translational applications. Cancer Gene Therapy. PMID 28548103 DOI: 10.1038/Cgt.2017.19 |
0.459 |
|
2017 |
Kolonin MG, Sergeeva A, Staquicini DI, Smith TL, Tarleton CA, Molldrem JJ, Sidman RL, Marchiò S, Pasqualini R, Arap W. Interaction between tumor cell surface receptor RAGE and proteinase 3 mediates prostate cancer metastasis to bone. Cancer Research. PMID 28428279 DOI: 10.1158/0008-5472.Can-16-0708 |
0.327 |
|
2017 |
Marchiò S, Bansal P, Pasqualini R, Arap W. An antivascular vaccine to boost self-immunity and strike the tumor. Proceedings of the National Academy of Sciences of the United States of America. PMID 28400521 DOI: 10.1073/Pnas.1701452114 |
0.394 |
|
2017 |
Lauer RC, Barry M, Wu J, Lee J, McCance DJ, Du R, Rao A, Dobroff AS, Dias-Neto E, Chen I, Pasqualini R, Arap W. PRUNE2 and PCA3 expression in paired non-malignant and tumor specimens from radical prostatectomy patients with gleason score 7 prostate cancer. Journal of Clinical Oncology. 35: e16582-e16582. DOI: 10.1200/Jco.2017.35.15_Suppl.E16582 |
0.351 |
|
2017 |
Dias-Neto E, Nunes DN, Thomas AM, Smith TL, Rao A, Lauer RC, Chen I, Arap W, Pasqualini R. PCA3 upregulation in prostate cancer: Analysis in a cohort of 497 subjects from TCGA. Journal of Clinical Oncology. 35: e16578-e16578. DOI: 10.1200/Jco.2017.35.15_Suppl.E16578 |
0.362 |
|
2016 |
Ferrara F, Staquicini DI, Driessen WH, D'Angelo S, Dobroff AS, Barry M, Lomo LC, Staquicini FI, Cardó-Vila M, Soghomonyan S, Alauddin MM, Flores LG, Arap MA, Lauer RC, Mathew P, ... ... Pasqualini R, et al. Targeted molecular-genetic imaging and ligand-directed therapy in aggressive variant prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791181 DOI: 10.1073/Pnas.1615400113 |
0.49 |
|
2016 |
Dobroff AS, D'Angelo S, Eckhardt BL, Ferrara F, Staquicini DI, Cardó-Vila M, Staquicini FI, Nunes DN, Kim K, Driessen WH, Hajitou A, Lomo LC, Barry M, Krishnamurthy S, Sahin A, ... ... Pasqualini R, et al. Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791177 DOI: 10.1073/Pnas.1615288113 |
0.43 |
|
2016 |
Silva RA, Giordano RJ, Gutierrez PS, Rocha VZ, Rudnicki M, Kee P, Abdalla DS, Puech-Leão P, Caramelli B, Arap W, Pasqualini R, Meneghetti JC, Marques FL, Khoobchandani M, Katti KV, et al. CTHRSSVVC Peptide as a Possible Early Molecular Imaging Target for Atherosclerosis. International Journal of Molecular Sciences. 17. PMID 27563889 DOI: 10.3390/Ijms17091383 |
0.409 |
|
2016 |
Cardó-Vila M, Marchiò S, Sato M, Staquicini FI, Smith TL, Bronk JK, Yin G, Zurita AJ, Sun M, Behrens C, Sidman RL, Lee JJ, Hong WK, Wistuba II, Arap W, ... Pasqualini R, et al. Interleukin-11 Receptor Is a Candidate Target for Ligand-Directed Therapy in Lung Cancer: Analysis of Clinical Samples and BMTP-11 Preclinical Activity. The American Journal of Pathology. PMID 27317903 DOI: 10.1016/J.Ajpath.2016.04.013 |
0.405 |
|
2016 |
Marchiò S, Sidman RL, Arap W, Pasqualini R. Brain endothelial cell-targeted gene therapy of neurovascular disorders. Embo Molecular Medicine. PMID 27189170 DOI: 10.15252/Emmm.201606407 |
0.308 |
|
2016 |
Bartolini A, Cardaci S, Lamba S, Oddo D, Marchiò C, Cassoni P, Amoreo CA, Corti G, Testori A, Bussolino F, Pasqualini R, Arap W, Corà D, Di Nicolantonio F, Marchio S. BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS Mutant Colorectal Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27143691 DOI: 10.1158/1078-0432.Ccr-15-2664 |
0.436 |
|
2016 |
Körbelin J, Sieber T, Michelfelder S, Lunding L, Spies E, Hunger A, Alawi M, Rapti K, Indenbirken D, Müller OJ, Pasqualini R, Arap W, Kleinschmidt JA, Trepel M. Pulmonary targeting of adeno-associated viral vectors by next-generation sequencing-guided screening of random capsid displayed peptide libraries. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27018516 DOI: 10.1038/Mt.2016.62 |
0.404 |
|
2016 |
Smith TL, Yuan Z, Cardó-Vila M, Sanchez Claros C, Adem A, Cui MH, Branch CA, Gelovani JG, Libutti SK, Sidman RL, Pasqualini R, Arap W. AAVP displaying octreotide for ligand-directed therapeutic transgene delivery in neuroendocrine tumors of the pancreas. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884209 DOI: 10.1073/Pnas.1525709113 |
0.478 |
|
2016 |
Dondossola E, Dobroff AS, Marchiò S, Cardó-Vila M, Hosoya H, Libutti SK, Corti A, Sidman RL, Arap W, Pasqualini R. Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858439 DOI: 10.1073/Pnas.1525697113 |
0.454 |
|
2016 |
Hosoya H, Dobroff AS, Driessen WH, Cristini V, Brinker LM, Staquicini FI, Cardó-Vila M, D'Angelo S, Ferrara F, Proneth B, Lin YS, Dunphy DR, Dogra P, Melancon MP, Stafford RJ, ... ... Pasqualini R, et al. Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release. Proceedings of the National Academy of Sciences of the United States of America. PMID 26839407 DOI: 10.1073/Pnas.1525796113 |
0.428 |
|
2016 |
Yao VJ, D'Angelo S, Butler KS, Theron C, Smith TL, Marchiò S, Gelovani JG, Sidman RL, Dobroff AS, Jeffrey Brinker C, Bradbury AR, Arap W, Pasqualini R. Ligand-targeted theranostic nanomedicines against cancer. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26772878 DOI: 10.1016/J.Jconrel.2016.01.002 |
0.545 |
|
2016 |
Kolonin M, Sergeeva A, Staquicini D, Molldrem JJ, Pasqualini R, Arap W. Neutrophil-Secreted Proteinase 3 Mediates Metastasis of Prostate Cancer Cells Expressing RAGE to the Bone Marrow Blood. 128: 1025-1025. DOI: 10.1182/Blood.V128.22.1025.1025 |
0.336 |
|
2016 |
Yuan Z, Srinivasab S, Alexander JF, Liu X, Arap W, Pasqualini R, Ferrari M, Libutti SK, Vilentchouk BG. Abstract 3911: Bacteriophage associated silicon particles (BASP) for targeting pancreatic neuroendocrine tumors Cancer Research. 76: 3911-3911. DOI: 10.1158/1538-7445.Am2016-3911 |
0.473 |
|
2015 |
Sidman RL, Li J, Lawrence M, Hu W, Musso GF, Giordano RJ, Cardó-Vila M, Pasqualini R, Arap W. The peptidomimetic Vasotide targets two retinal VEGF receptors and reduces pathological angiogenesis in murine and nonhuman primate models of retinal disease. Science Translational Medicine. 7: 309ra165. PMID 26468327 DOI: 10.1126/Scitranslmed.Aac4882 |
0.32 |
|
2015 |
Bartolini A, Di Paolo D, Noghero A, Murgia D, Sementa AR, Cilli M, Pasqualini R, Arap W, Bussolino F, Ponzoni M, Pastorino F, Marchiò S. The Neuronal Pentraxin-2 Pathway Is an Unrecognized Target in Human Neuroblastoma, Which Also Offers Prognostic Value in Patients. Cancer Research. 75: 4265-71. PMID 26294210 DOI: 10.1158/0008-5472.Can-15-0649 |
0.532 |
|
2015 |
Salameh A, Lee AK, Cardó-Vila M, Nunes DN, Efstathiou E, Staquicini FI, Dobroff AS, Marchiò S, Navone NM, Hosoya H, Lauer RC, Wen S, Salmeron CC, Hoang A, Newsham I, ... ... Pasqualini R, et al. PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3. Proceedings of the National Academy of Sciences of the United States of America. PMID 26080435 DOI: 10.1073/Pnas.1507882112 |
0.326 |
|
2015 |
Pasqualini R, Millikan RE, Christianson DR, Cardó-Vila M, Driessen WH, Giordano RJ, Hajitou A, Hoang AG, Wen S, Barnhart KF, Baze WB, Marcott VD, Hawke DH, Do KA, Navone NM, et al. Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man study. Cancer. 121: 2411-21. PMID 25832466 DOI: 10.1002/Cncr.29344 |
0.454 |
|
2015 |
Karjalainen K, Jaalouk DE, Bueso-Ramos C, Bover L, Sun Y, Kuniyasu A, Driessen WH, Cardó-Vila M, Rietz C, Zurita AJ, O'Brien S, Kantarjian HM, Cortes JE, Calin GA, Koivunen E, ... ... Pasqualini R, et al. Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 3041-51. PMID 25779950 DOI: 10.1158/1078-0432.Ccr-13-3059 |
0.428 |
|
2015 |
Mandelin J, Cardó-Vila M, Driessen WH, Mathew P, Navone NM, Lin SH, Logothetis CJ, Rietz AC, Dobroff AS, Proneth B, Sidman RL, Pasqualini R, Arap W. Selection and identification of ligand peptides targeting a model of castrate-resistant osteogenic prostate cancer and their receptors. Proceedings of the National Academy of Sciences of the United States of America. 112: 3776-81. PMID 25762070 DOI: 10.1073/Pnas.1500128112 |
0.427 |
|
2015 |
Ardelt PU, Ebbing J, Adams F, Reiss C, Arap W, Pasqualini R, Bachmann A, Wetterauer U, Riedmiller H, Kneitz B. An anti-ubiquitin antibody response in transitional cell carcinoma of the urinary bladder. Plos One. 10: e0118646. PMID 25742283 DOI: 10.1371/Journal.Pone.0118646 |
0.329 |
|
2015 |
Mintz PJ, Rietz AC, Cardó-Vila M, Ozawa MG, Dondossola E, Do KA, Kim J, Troncoso P, Logothetis CJ, Sidman RL, Pasqualini R, Arap W. Discovery and horizontal follow-up of an autoantibody signature in human prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 112: 2515-20. PMID 25675522 DOI: 10.1073/Pnas.1500097112 |
0.341 |
|
2015 |
Christianson DR, Dobroff AS, Proneth B, Zurita AJ, Salameh A, Dondossola E, Makino J, Bologa CG, Smith TL, Yao VJ, Calderone TL, O'Connell DJ, Oprea TI, Kataoka K, Cahill DJ, ... ... Pasqualini R, et al. Ligand-directed targeting of lymphatic vessels uncovers mechanistic insights in melanoma metastasis. Proceedings of the National Academy of Sciences of the United States of America. 112: 2521-6. PMID 25659743 DOI: 10.1073/Pnas.1424994112 |
0.456 |
|
2015 |
Dobroff AS, Rangel R, Guzman-Roja L, Salmeron CC, Gelovani JG, Sidman RL, Bologa CG, Oprea TI, Brinker CJ, Pasqualini R, Arap W. Ligand-directed profiling of organelles with internalizing phage libraries. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. 79: 30.4.1-30.4.30. PMID 25640897 DOI: 10.1002/0471140864.Ps3004S79 |
0.432 |
|
2015 |
Staquicini FI, Qian MD, Salameh A, Dobroff AS, Edwards JK, Cimino DF, Moeller BJ, Kelly P, Nunez MI, Tang X, Liu DD, Lee JJ, Hong WK, Ferrara F, Bradbury AR, ... ... Pasqualini R, et al. Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer. The Journal of Biological Chemistry. 290: 7345-59. PMID 25623065 DOI: 10.1074/Jbc.M114.630525 |
0.345 |
|
2015 |
Lauer RC, Friend SC, Rietz C, Pasqualini R, Arap W. Drug design strategies for the treatment of prostate cancer. Expert Opinion On Drug Discovery. 10: 81-90. PMID 25366417 DOI: 10.1517/17460441.2015.978855 |
0.354 |
|
2015 |
Staquicini F, Dobroff A, Ferrara F, D'Angelo S, Bradbury AR, Arap W, Pasqualini R. Abstract LB-006: Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-006 |
0.355 |
|
2015 |
Dobroff AS, Eckhardt BL, Salmeron CC, Cimino DF, Arap W, Pasqualini R. Abstract 3543: Ligand-directed and transcription-based molecular imaging and treatment of cancer Cancer Research. 75: 3543-3543. DOI: 10.1158/1538-7445.Am2015-3543 |
0.495 |
|
2014 |
Dondossola E, Corti A, Sidman RL, Arap W, Pasqualini R. Bone marrow-derived CD13(+) cells sustain tumor progression: A potential non-malignant target for anticancer therapy. Oncoimmunology. 3: e27716. PMID 25339996 DOI: 10.4161/Onci.27716 |
0.338 |
|
2014 |
Karjalainen K, Pasqualini R, Cortes JE, Kornblau SM, Lichtiger B, O'Brien S, Kantarjian HM, Sidman RL, Arap W, Koivunen E. Design, development, and validation of a high-throughput drug-screening assay for targeting of human leukemia. Cancer. 120: 589-602. PMID 24496871 DOI: 10.1002/Cncr.28419 |
0.33 |
|
2013 |
Srinivasan S, Alexander JF, Driessen WH, Leonard F, Ye H, Liu X, Arap W, Pasqualini R, Ferrari M, Godin B. Bacteriophage Associated Silicon Particles: Design and Characterization of a Novel Theranostic Vector with Improved Payload Carrying Potential. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 1. PMID 24409342 DOI: 10.1039/C3Tb20595A |
0.387 |
|
2013 |
Dondossola E, Rangel R, Guzman-Rojas L, Barbu EM, Hosoya H, St John LS, Molldrem JJ, Corti A, Sidman RL, Arap W, Pasqualini R. CD13-positive bone marrow-derived myeloid cells promote angiogenesis, tumor growth, and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 110: 20717-22. PMID 24297924 DOI: 10.1073/Pnas.1321139110 |
0.378 |
|
2013 |
Barbu EM, Shirazi F, McGrath DM, Albert N, Sidman RL, Pasqualini R, Arap W, Kontoyiannis DP. An antimicrobial peptidomimetic induces Mucorales cell death through mitochondria-mediated apoptosis. Plos One. 8: e76981. PMID 24098573 DOI: 10.1371/Journal.Pone.0076981 |
0.313 |
|
2013 |
Rangel R, Dobroff AS, Guzman-Rojas L, Salmeron CC, Gelovani JG, Sidman RL, Pasqualini R, Arap W. Targeting mammalian organelles with internalizing phage (iPhage) libraries. Nature Protocols. 8: 1916-39. PMID 24030441 DOI: 10.1038/Nprot.2013.119 |
0.411 |
|
2013 |
Chintalgattu V, Rees ML, Culver JC, Goel A, Jiffar T, Zhang J, Dunner K, Pati S, Bankson JA, Pasqualini R, Arap W, Bryan NS, Taegtmeyer H, Langley RR, Yao H, et al. Coronary microvascular pericytes are the cellular target of sunitinib malate-induced cardiotoxicity. Science Translational Medicine. 5: 187ra69. PMID 23720580 DOI: 10.1126/Scitranslmed.3005066 |
0.313 |
|
2013 |
Loi M, Di Paolo D, Soster M, Brignole C, Bartolini A, Emionite L, Sun J, Becherini P, Curnis F, Petretto A, Sani M, Gori A, Milanese M, Gambini C, Longhi R, ... ... Pasqualini R, et al. Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings. Journal of Controlled Release : Official Journal of the Controlled Release Society. 170: 233-41. PMID 23714122 DOI: 10.1016/J.Jconrel.2013.04.029 |
0.524 |
|
2013 |
Miao YR, Eckhardt BL, Cao Y, Pasqualini R, Argani P, Arap W, Ramsay RG, Anderson RL. Inhibition of established micrometastases by targeted drug delivery via cell surface-associated GRP78. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 2107-16. PMID 23470966 DOI: 10.1158/1078-0432.Ccr-12-2991 |
0.449 |
|
2013 |
Arap W, Pasqualini R, Montalti M, Petrizza L, Prodi L, Rampazzo E, Zaccheroni N, Marchiò S. Luminescent silica nanoparticles for cancer diagnosis. Current Medicinal Chemistry. 20: 2195-2211. PMID 23458621 DOI: 10.2174/0929867311320170005 |
0.322 |
|
2013 |
León-Novelo LG, Müller P, Arap W, Kolonin M, Sun J, Pasqualini R, Do KA. Semiparametric Bayesian inference for phage display data. Biometrics. 69: 174-83. PMID 23339534 DOI: 10.1111/J.1541-0420.2012.01817.X |
0.323 |
|
2013 |
Yuan Z, Syrkin G, Adem A, Geha R, Pastoriza J, Vrikshajanani C, Smith T, Quinn TJ, Alemu G, Cho H, Barrett CJ, Arap W, Pasqualini R, Libutti SK. Blockade of inhibitors of apoptosis (IAPs) in combination with tumor-targeted delivery of tumor necrosis factor-α leads to synergistic antitumor activity. Cancer Gene Therapy. 20: 46-56. PMID 23154431 DOI: 10.1038/Cgt.2012.83 |
0.346 |
|
2013 |
Loi M, Paolo DD, Soster M, Brignole C, Bartolini A, Emionite L, Sun J, Becherini P, Curnis F, Petretto A, Sani M, Gori A, Gambini C, Longhi R, Cilli M, ... ... Pasqualini R, et al. Abstract 5620: Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings. Cancer Research. 73: 5620-5620. DOI: 10.1158/1538-7445.Am2013-5620 |
0.534 |
|
2013 |
Bronk L, Polf J, Driessen W, Gillin M, Arap W, Pasqualini R. TU-A-108-11: Nanoscaffold-Enhanced Proton Therapy Medical Physics. 40: 422-422. DOI: 10.1118/1.4815334 |
0.327 |
|
2012 |
Marchiò S, Soster M, Cardaci S, Muratore A, Bartolini A, Barone V, Ribero D, Monti M, Bovino P, Sun J, Giavazzi R, Asioli S, Cassoni P, Capussotti L, Pucci P, ... ... Pasqualini R, et al. A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6. Embo Molecular Medicine. 4: 1156-75. PMID 23070965 DOI: 10.1002/Emmm.201101164 |
0.349 |
|
2012 |
Rangel R, Guzman-Rojas L, le Roux LG, Staquicini FI, Hosoya H, Barbu EM, Ozawa MG, Nie J, Jr KD, Langley RR, Sage EH, Koivunen E, Gelovani JG, Lobb RR, Sidman RL, ... Pasqualini R, et al. Combinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells. Nature Communications. 3: 788. PMID 22510693 DOI: 10.1038/Ncomms1773 |
0.451 |
|
2012 |
Guzman-Rojas L, Rangel R, Salameh A, Edwards JK, Dondossola E, Kim YG, Saghatelian A, Giordano RJ, Kolonin MG, Staquicini FI, Koivunen E, Sidman RL, Arap W, Pasqualini R. Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment. Proceedings of the National Academy of Sciences of the United States of America. 109: 1637-42. PMID 22307623 DOI: 10.1073/Pnas.1120790109 |
0.41 |
|
2012 |
Corti A, Pastorino F, Curnis F, Arap W, Ponzoni M, Pasqualini R. Targeted drug delivery and penetration into solid tumors. Medicinal Research Reviews. 32: 1078-91. PMID 21287572 DOI: 10.1002/Med.20238 |
0.432 |
|
2012 |
Karjalainen K, Jaalouk DE, Bueso-Ramos CE, Zurita AJ, Kuniyasu A, Eckhardt BL, Marini FC, Lichtiger B, O'Brien S, Kantarjian HM, Cortes JE, Koivunen E, Arap W, Pasqualini R. Abstract 2903: Therapeutic targeting of leukemia and lymphoma with a neuropilin-1 binding pro-apoptotic peptide Cancer Research. 72: 2903-2903. DOI: 10.1158/1538-7445.Am2012-2903 |
0.469 |
|
2012 |
Eckhardt B, Miao R, Cao Y, Driessen W, Krishnamurthy S, Arap W, Ueno N, Anderson R, Pasqualini R. Abstract P3-10-09: Peptide-based molecular targeting of inflammatory breast cancer. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P3-10-09 |
0.434 |
|
2011 |
Staquicini FI, Cardó-Vila M, Kolonin MG, Trepel M, Edwards JK, Nunes DN, Sergeeva A, Efstathiou E, Sun J, Almeida NF, Tu SM, Botz GH, Wallace MJ, O'Connell DJ, Krajewski S, ... ... Pasqualini R, et al. Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients. Proceedings of the National Academy of Sciences of the United States of America. 108: 18637-42. PMID 22049339 DOI: 10.1073/Pnas.1114503108 |
0.41 |
|
2011 |
Polf JC, Bronk LF, Driessen WH, Arap W, Pasqualini R, Gillin M. Enhanced relative biological effectiveness of proton radiotherapy in tumor cells with internalized gold nanoparticles. Applied Physics Letters. 98: 193702. PMID 21915155 DOI: 10.1063/1.3589914 |
0.343 |
|
2011 |
Carraro DM, Ferreira EN, de Campos Molina G, Puga RD, Abrantes EF, Trapé AP, Eckhardt BL, Ekhardt BL, Nunes DN, Brentani MM, Arap W, Pasqualini R, Brentani H, Dias-Neto E, Brentani RR. Poly (A)+ transcriptome assessment of ERBB2-induced alterations in breast cell lines. Plos One. 6: e21022. PMID 21731642 DOI: 10.1371/Journal.Pone.0021022 |
0.369 |
|
2011 |
Moeller BJ, Sidman RL, Pasqualini R, Arap W. Discovery of DNA repair inhibitors by combinatorial library profiling. Cancer Research. 71: 1816-24. PMID 21343400 DOI: 10.1158/0008-5472.Can-10-2361 |
0.344 |
|
2011 |
Staquicini FI, Ozawa MG, Moya CA, Driessen WH, Barbu EM, Nishimori H, Soghomonyan S, Flores LG, Liang X, Paolillo V, Alauddin MM, Basilion JP, Furnari FB, Bogler O, Lang FF, ... ... Pasqualini R, et al. Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. The Journal of Clinical Investigation. 121: 161-73. PMID 21183793 DOI: 10.1172/Jci44798 |
0.787 |
|
2011 |
Karjalainen K, Jaalouk DE, Bueso-Ramos CE, Zurita AJ, Kuniyasu A, Eckhardt BL, Marini FC, Lichtiger B, O'Brien S, Kantarjian HM, Cortes JE, Koivunen E, Arap W, Pasqualini R. Targeting neuropilin-1 in human leukemia and lymphoma. Blood. 117: 920-7. PMID 21063027 DOI: 10.1182/Blood-2010-05-282921 |
0.441 |
|
2011 |
Gesteira TF, Coulson-Thomas VJ, Taunay-Rodrigues A, Oliveira V, Thacker BE, Juliano MA, Pasqualini R, Arap W, Tersariol IL, Nader HB, Esko JD, Pinhal MA. Inhibitory peptides of the sulfotransferase domain of the heparan sulfate enzyme, N-deacetylase-N-sulfotransferase-1. The Journal of Biological Chemistry. 286: 5338-46. PMID 20129923 DOI: 10.1074/Jbc.M110.100719 |
0.352 |
|
2011 |
Marchiò S, Paolo DD, Loi M, Soster M, Bartolini A, Cilli M, Sun J, Gambini C, Longhi R, Curnis F, Corti A, Arap W, Pasqualini R, Ponzoni M, Pastorino F. Abstract 3625: Novel phage-display derived peptides for tumor- and vasculature-targeted therapies in neuroblastoma Cancer Research. 71: 3625-3625. DOI: 10.1158/1538-7445.Am2011-3625 |
0.532 |
|
2010 |
Staquicini FI, Moeller BJ, Arap W, Pasqualini R. Combinatorial vascular targeting in translational medicine. Proteomics. Clinical Applications. 4: 626-32. PMID 21137081 DOI: 10.1002/Prca.200900213 |
0.405 |
|
2010 |
Tonelli RR, Giordano RJ, Barbu EM, Torrecilhas AC, Kobayashi GS, Langley RR, Arap W, Pasqualini R, Colli W, Alves MJ. Role of the gp85/trans-sialidases in Trypanosoma cruzi tissue tropism: preferential binding of a conserved peptide motif to the vasculature in vivo. Plos Neglected Tropical Diseases. 4: e864. PMID 21072227 DOI: 10.1371/Journal.Pntd.0000864 |
0.343 |
|
2010 |
Staquicini FI, Sidman RL, Arap W, Pasqualini R. Phage display technology for stem cell delivery and systemic therapy. Advanced Drug Delivery Reviews. 62: 1213-6. PMID 20932865 DOI: 10.1016/J.Addr.2010.09.014 |
0.41 |
|
2010 |
Moeller BJ, Arap W, Pasqualini R. Targeting synthetic lethality in DNA damage repair pathways as an anti-cancer strategy. Current Drug Targets. 11: 1336-40. PMID 20840076 DOI: 10.2174/1389450111007011336 |
0.343 |
|
2010 |
Driessen WH, Bronk LF, Edwards JK, Proneth B, Souza GR, Decuzzi P, Pasqualini R, Arap W. On the synergistic effects of ligand-mediated and phage-intrinsic properties during in vivo selection. Advances in Genetics. 69: 115-33. PMID 20807605 DOI: 10.1016/S0065-2660(10)69005-0 |
0.447 |
|
2010 |
Sato M, Yao VJ, Arap W, Pasqualini R. GRP78 signaling hub a receptor for targeted tumor therapy. Advances in Genetics. 69: 97-114. PMID 20807604 DOI: 10.1016/S0065-2660(10)69006-2 |
0.489 |
|
2010 |
Pasqualini R, Moeller BJ, Arap W. Leveraging molecular heterogeneity of the vascular endothelium for targeted drug delivery and imaging. Seminars in Thrombosis and Hemostasis. 36: 343-51. PMID 20490984 DOI: 10.1055/S-0030-1253456 |
0.398 |
|
2010 |
Loi M, Marchiò S, Becherini P, Di Paolo D, Soster M, Curnis F, Brignole C, Pagnan G, Perri P, Caffa I, Longhi R, Nico B, Bussolino F, Gambini C, Ribatti D, ... ... Pasqualini R, et al. Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma. Journal of Controlled Release : Official Journal of the Controlled Release Society. 145: 66-73. PMID 20346382 DOI: 10.1016/J.Jconrel.2010.03.015 |
0.484 |
|
2010 |
Cardó-Vila M, Giordano RJ, Sidman RL, Bronk LF, Fan Z, Mendelsohn J, Arap W, Pasqualini R. From combinatorial peptide selection to drug prototype (II): targeting the epidermal growth factor receptor pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 5118-23. PMID 20190183 DOI: 10.1073/Pnas.0915146107 |
0.345 |
|
2010 |
Giordano RJ, Cardó-Vila M, Salameh A, Anobom CD, Zeitlin BD, Hawke DH, Valente AP, Almeida FC, Nör JE, Sidman RL, Pasqualini R, Arap W. From combinatorial peptide selection to drug prototype (I): targeting the vascular endothelial growth factor receptor pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 5112-7. PMID 20190181 DOI: 10.1073/Pnas.0915141107 |
0.407 |
|
2010 |
Weaver MS, Workman G, Cardo-Vila M, Arap W, Pasqualini R, Sage EH. Processing of the matricellular protein hevin in mouse brain is dependent on ADAMTS4. The Journal of Biological Chemistry. 285: 5868-77. PMID 20018883 DOI: 10.1074/Jbc.M109.070318 |
0.32 |
|
2010 |
Ardelt PU, Kneitz B, Adam P, Reiss C, Kocot A, Fensterle J, Chen L, Pasqualini R, Arap W, Gerharz EW, Riedmiller H. Reactive antibodies against bacillus Calmette-Guerin heat-shock protein-65 potentially predict the outcome of immunotherapy for high-grade transitional cell carcinoma of the bladder. Cancer. 116: 600-9. PMID 19957324 DOI: 10.1002/Cncr.24770 |
0.312 |
|
2010 |
Souza GR, Staquicini FI, Christianson DR, Ozawa MG, Miller JH, Pasqualini R, Arap W. Combinatorial targeting and nanotechnology applications. Biomedical Microdevices. 12: 597-606. PMID 19669890 DOI: 10.1007/S10544-009-9340-6 |
0.409 |
|
2010 |
Staquicini FI, Ozawa MG, Moya CA, Driessen WHP, Barbu EM, Soghomonyan S, Flores LG, Alauddin MM, Gelovani JG, Liang X, Hook M, Basilion JP, Bogler O, Sidman RL, Cavenee WK, ... Pasqualini R, et al. Abstract 582: Targeting the blood-brain barrier with a non-canonical iron-mimicry mechanism: A translational approach for the detection and treatment of human brain tumors Cancer Research. 70: 582-582. DOI: 10.1158/1538-7445.Am10-582 |
0.449 |
|
2010 |
Driessen WH, Mandelin J, Cardó-Vila M, Kim J, Mathew P, Navone NM, Soghomonyan S, Flores LG, Alauddin MM, Gelovani JG, Pasqualini R, Arap W. Abstract 4322: Ligand-directed therapy and molecular imaging in a mouse model of androgen-independent osteogenic prostate cancer Cancer Research. 70: 4322-4322. DOI: 10.1158/1538-7445.Am10-4322 |
0.445 |
|
2010 |
Proneth B, Driessen WH, Hajitou A, Staquicini FI, Arap W, Pasqualini R. Abstract 1625: Discovery of a breast cancer targeting peptide with anti-tumor activity Cancer Research. 70: 1625-1625. DOI: 10.1158/1538-7445.Am10-1625 |
0.464 |
|
2009 |
Staquicini FI, Pasqualini R, Arap W. Ligand-directed profiling: applications to target drug discovery in cancer. Expert Opinion On Drug Discovery. 4: 51-9. PMID 23480336 DOI: 10.1517/17460440802628152 |
0.467 |
|
2009 |
Dias-Neto E, Nunes DN, Giordano RJ, Sun J, Botz GH, Yang K, Setubal JC, Pasqualini R, Arap W. Next-generation phage display: integrating and comparing available molecular tools to enable cost-effective high-throughput analysis. Plos One. 4: e8338. PMID 20020040 DOI: 10.1371/Journal.Pone.0008338 |
0.345 |
|
2009 |
Driessen WH, Ozawa MG, Arap W, Pasqualini R. Ligand-directed cancer gene therapy to angiogenic vasculature. Advances in Genetics. 67: 103-21. PMID 19914451 DOI: 10.1016/S0065-2660(09)67004-8 |
0.452 |
|
2009 |
Giordano RJ, Edwards JK, Tuder RM, Arap W, Pasqualini R. Combinatorial ligand-directed lung targeting. Proceedings of the American Thoracic Society. 6: 411-5. PMID 19687212 DOI: 10.1513/pats.200903-014AW |
0.319 |
|
2009 |
Trepel M, Stoneham CA, Eleftherohorinou H, Mazarakis ND, Pasqualini R, Arap W, Hajitou A. A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer. Molecular Cancer Therapeutics. 8: 2383-91. PMID 19671758 DOI: 10.1158/1535-7163.Mct-09-0110 |
0.457 |
|
2009 |
Stefanidakis M, Karjalainen K, Jaalouk DE, Gahmberg CG, O'Brien S, Pasqualini R, Arap W, Koivunen E. Role of leukemia cell invadosome in extramedullary infiltration. Blood. 114: 3008-17. PMID 19636064 DOI: 10.1182/Blood-2008-04-148643 |
0.336 |
|
2009 |
Zhang Y, Daquinag A, Traktuev DO, Amaya-Manzanares F, Simmons PJ, March KL, Pasqualini R, Arap W, Kolonin MG. White adipose tissue cells are recruited by experimental tumors and promote cancer progression in mouse models. Cancer Research. 69: 5259-66. PMID 19491274 DOI: 10.1158/0008-5472.Can-08-3444 |
0.423 |
|
2009 |
Moeller BJ, Pasqualini R, Arap W. Targeting cancer-specific synthetic lethality in double-strand DNA break repair. Cell Cycle (Georgetown, Tex.). 8: 1872-6. PMID 19440052 DOI: 10.4161/Cc.8.12.8743 |
0.366 |
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2009 |
Paoloni MC, Tandle A, Mazcko C, Hanna E, Kachala S, Leblanc A, Newman S, Vail D, Henry C, Thamm D, Sorenmo K, Hajitou A, Pasqualini R, Arap W, Khanna C, et al. Launching a novel preclinical infrastructure: comparative oncology trials consortium directed therapeutic targeting of TNFalpha to cancer vasculature. Plos One. 4: e4972. PMID 19330034 DOI: 10.1371/Journal.Pone.0004972 |
0.329 |
|
2009 |
Lewis VO, Ozawa MG, Deavers MT, Wang G, Shintani T, Arap W, Pasqualini R. The interleukin-11 receptor alpha as a candidate ligand-directed target in osteosarcoma: consistent data from cell lines, orthotopic models, and human tumor samples. Cancer Research. 69: 1995-9. PMID 19244100 DOI: 10.1158/0008-5472.Can-08-4845 |
0.367 |
|
2009 |
Marchiò S, Arap W, Pasqualini R. Targeting the extracellular signature of metastatic colorectal cancers. Expert Opinion On Therapeutic Targets. 13: 363-79. PMID 19236157 DOI: 10.1517/14728220902762910 |
0.375 |
|
2009 |
Mandelin J, Lin EC, Hu DD, Knowles SK, Do KA, Wang X, Sage EH, Smith JW, Arap W, Pasqualini R. Extracellular and intracellular mechanisms that mediate the metastatic activity of exogenous osteopontin. Cancer. 115: 1753-64. PMID 19224553 DOI: 10.1002/Cncr.24170 |
0.318 |
|
2009 |
Mintz PJ, Cardó-Vila M, Ozawa MG, Hajitou A, Rangel R, Guzman-Rojas L, Christianson DR, Arap MA, Giordano RJ, Souza GR, Easley J, Salameh A, Oliviero S, Brentani RR, Koivunen E, ... ... Pasqualini R, et al. An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment. Proceedings of the National Academy of Sciences of the United States of America. 106: 2182-7. PMID 19168626 DOI: 10.1073/Pnas.0807543105 |
0.408 |
|
2009 |
Tandle A, Hanna E, Lorang D, Hajitou A, Moya CA, Pasqualini R, Arap W, Adem A, Starker E, Hewitt S, Libutti SK. Tumor vasculature-targeted delivery of tumor necrosis factor-alpha. Cancer. 115: 128-39. PMID 19090007 DOI: 10.1002/Cncr.24001 |
0.756 |
|
2009 |
Tagore DM, Nolte WM, Neveu JM, Rangel R, Guzman-Rojas L, Pasqualini R, Arap W, Lane WS, Saghatelian A. Peptidase substrates via global peptide profiling. Nature Chemical Biology. 5: 23-5. PMID 19011639 DOI: 10.1038/Nchembio.126 |
0.338 |
|
2009 |
Decuzzi P, Pasqualini R, Arap W, Ferrari M. Intravascular delivery of particulate systems: does geometry really matter? Pharmaceutical Research. 26: 235-43. PMID 18712584 DOI: 10.1007/S11095-008-9697-X |
0.348 |
|
2008 |
Trepel M, Pasqualini R, Arap W. Chapter 4. Screening phage-display Peptide libraries for vascular targeted peptides. Methods in Enzymology. 445: 83-106. PMID 19022056 DOI: 10.1016/S0076-6879(08)03004-8 |
0.48 |
|
2008 |
Cardó-Vila M, Zurita AJ, Giordano RJ, Sun J, Rangel R, Guzman-Rojas L, Anobom CD, Valente AP, Almeida FC, Lahdenranta J, Kolonin MG, Arap W, Pasqualini R. A ligand peptide motif selected from a cancer patient is a receptor-interacting site within human interleukin-11. Plos One. 3: e3452. PMID 18941632 DOI: 10.1371/Journal.Pone.0003452 |
0.335 |
|
2008 |
Staquicini FI, Tandle A, Libutti SK, Sun J, Zigler M, Bar-Eli M, Aliperti F, Pérez EC, Gershenwald JE, Mariano M, Pasqualini R, Arap W, Lopes JD. A subset of host B lymphocytes controls melanoma metastasis through a melanoma cell adhesion molecule/MUC18-dependent interaction: evidence from mice and humans. Cancer Research. 68: 8419-28. PMID 18922915 DOI: 10.1158/0008-5472.Can-08-1242 |
0.38 |
|
2008 |
Giordano RJ, Lahdenranta J, Zhen L, Chukwueke U, Petrache I, Langley RR, Fidler IJ, Pasqualini R, Tuder RM, Arap W. Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse. The Journal of Biological Chemistry. 283: 29447-60. PMID 18718906 DOI: 10.1074/Jbc.M804595200 |
0.339 |
|
2008 |
Nie J, Chang B, Traktuev DO, Sun J, March K, Chan L, Sage EH, Pasqualini R, Arap W, Kolonin MG. IFATS collection: Combinatorial peptides identify alpha5beta1 integrin as a receptor for the matricellular protein SPARC on adipose stromal cells. Stem Cells (Dayton, Ohio). 26: 2735-45. PMID 18583538 DOI: 10.1634/Stemcells.2008-0212 |
0.452 |
|
2008 |
Corti A, Curnis F, Arap W, Pasqualini R. The neovasculature homing motif NGR: more than meets the eye. Blood. 112: 2628-35. PMID 18574027 DOI: 10.1182/Blood-2008-04-150862 |
0.471 |
|
2008 |
Ozawa MG, Zurita AJ, Dias-Neto E, Nunes DN, Sidman RL, Gelovani JG, Arap W, Pasqualini R. Beyond receptor expression levels: the relevance of target accessibility in ligand-directed pharmacodelivery systems. Trends in Cardiovascular Medicine. 18: 126-32. PMID 18555185 DOI: 10.1016/J.Tcm.2008.03.001 |
0.455 |
|
2008 |
Hajitou A, Lev DC, Hannay JA, Korchin B, Staquicini FI, Soghomonyan S, Alauddin MM, Benjamin RS, Pollock RE, Gelovani JG, Pasqualini R, Arap W. A preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging. Proceedings of the National Academy of Sciences of the United States of America. 105: 4471-6. PMID 18337507 DOI: 10.1073/Pnas.0712184105 |
0.418 |
|
2008 |
Nishimura S, Takahashi S, Kamikatahira H, Kuroki Y, Jaalouk DE, O'Brien S, Koivunen E, Arap W, Pasqualini R, Nakayama H, Kuniyasu A. Combinatorial targeting of the macropinocytotic pathway in leukemia and lymphoma cells. The Journal of Biological Chemistry. 283: 11752-62. PMID 18292083 DOI: 10.1074/Jbc.M708849200 |
0.444 |
|
2008 |
Wood KC, Azarin SM, Arap W, Pasqualini R, Langer R, Hammond PT. Tumor-targeted gene delivery using molecularly engineered hybrid polymers functionalized with a tumor-homing peptide. Bioconjugate Chemistry. 19: 403-5. PMID 18189340 DOI: 10.1021/Bc700408R |
0.41 |
|
2008 |
Sato M, Arap W, Pasqualini R. Molecular targets on blood vessels for cancer therapies in clinical trials. Oncology (Williston Park, N.Y.). 21: 1346-52; discussion . PMID 18080618 |
0.343 |
|
2008 |
Binder M, Müller F, Frick M, Wehr C, Pantic M, Pfeifer D, Pasqualini R, Arap W, Veelken H, Mertelsmann RH, Trepel M. B-Cell Receptor Profiling Suggests a Limited Number of Antigens Involved in the Pathogenesis of Chronic Lymphocytic Leukemia. Blood. 112: 2060-2060. DOI: 10.1182/Blood.V112.11.2060.2060 |
0.405 |
|
2008 |
Pastorino F, Marchiò S, Paolo DD, Loi M, Corti A, Bussolino F, Ribatti D, Arap W, Pasqualini R, Ponzoni M. 126 POSTER Novel phage display-derived peptides for tumor- and vascular- targeted therapies against neuroblastoma Ejc Supplements. 6: 41. DOI: 10.1016/S1359-6349(08)72058-5 |
0.468 |
|
2007 |
Jaalouk DE, Ozawa MG, Sun J, Lahdenranta J, Schlingemann RO, Pasqualini R, Arap W. The original pathologische anatomie leiden-endothelium monoclonal antibody recognizes a vascular endothelial growth factor-binding site within neuropilin-1 Cancer Research. 67: 9623-9629. PMID 17942890 DOI: 10.1158/0008-5472.Can-07-2737 |
0.333 |
|
2007 |
Bover LC, Cardó-Vila M, Kuniyasu A, Sun J, Rangel R, Takeya M, Aggarwal BB, Arap W, Pasqualini R. A Previously Unrecognized Protein-Protein Interaction between TWEAK and CD163: Potential Biological Implications Journal of Immunology. 178: 8183-8194. PMID 17548657 DOI: 10.4049/Jimmunol.178.12.8183 |
0.326 |
|
2007 |
Lahdenranta J, Sidman RL, Pasqualini R, Arap W. Treatment of hypoxia-induced retinopathy with targeted proapoptotic peptidomimetic in a mouse model of disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3272-8. PMID 17513561 DOI: 10.1096/Fj.07-8273Com |
0.437 |
|
2007 |
Hajitou A, Rangel R, Trepel M, Soghomonyan S, Gelovani JG, Alauddin MM, Pasqualini R, Arap W. Design and construction of targeted AAVP vectors for mammalian cell transduction Nature Protocols. 2: 523-531. PMID 17406616 DOI: 10.1038/Nprot.2007.51 |
0.428 |
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2007 |
Rangel R, Sun Y, Guzman-Rojas L, Ozawa MG, Sun J, Giordano RJ, Van Pelt CS, Tinkey PT, Behringer RR, Sidman RL, Arap W, Pasqualini R. Impaired angiogenesis in aminopeptidase N-null mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 4588-93. PMID 17360568 DOI: 10.1073/Pnas.0611653104 |
0.319 |
|
2007 |
Christianson DR, Ozawa MG, Pasqualini R, Arap W. Techniques to Decipher Molecular Diversity by Phage Display Methods of Molecular Biology. 357: 385-406. PMID 17172704 DOI: 10.1385/1-59745-214-9:385 |
0.445 |
|
2007 |
Ji Y, Yin G, Tsui K, Kolonin MG, Sun J, Arap W, Pasqualini R, Do K. Bayesian mixture models for complex high dimensional count data in phage display experiments Journal of the Royal Statistical Society: Series C (Applied Statistics). 56: 139-152. DOI: 10.1111/J.1467-9876.2007.00570.X |
0.386 |
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2006 |
Sergeeva A, Kolonin MG, Molldrem JJ, Pasqualini R, Arap W. Display technologies: application for the discovery of drug and gene delivery agents. Advanced Drug Delivery Reviews. 58: 1622-1654. PMID 17123658 DOI: 10.1016/J.Addr.2006.09.018 |
0.45 |
|
2006 |
Kzhyshkowska J, Workman G, Cardó-Vila M, Arap W, Pasqualini R, Gratchev A, Krusell L, Goerdt S, Sage EH. Novel function of alternatively activated macrophages: stabilin-1-mediated clearance of SPARC. Journal of Immunology (Baltimore, Md. : 1950). 176: 5825-32. PMID 16670288 DOI: 10.4049/Jimmunol.176.10.5825 |
0.41 |
|
2006 |
Hajitou A, Trepel M, Lilley CE, Soghomonyan S, Alauddin MM, Marini FC, Restel BH, Ozawa MG, Moya CA, Rangel R, Sun Y, Zaoui K, Schmidt M, von Kalle C, Weitzman MD, ... ... Pasqualini R, et al. A hybrid vector for ligand-directed tumor targeting and molecular imaging. Cell. 125: 385-98. PMID 16630824 DOI: 10.1016/J.Cell.2006.02.042 |
0.776 |
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2006 |
Kolonin MG, Sun J, Do KA, Vidal CI, Ji Y, Baggerly KA, Pasqualini R, Arap W. Synchronous selection of homing peptides for multiple tissues by in vivo phage display. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 979-81. PMID 16581960 DOI: 10.1096/Fj.05-5186Fje |
0.444 |
|
2006 |
Hajitou A, Pasqualini R, Arap W. Vascular targeting: Recent advances and therapeutic perspectives Trends in Cardiovascular Medicine. 16: 80-88. PMID 16546688 DOI: 10.1016/J.Tcm.2006.01.003 |
0.452 |
|
2006 |
Yao VJ, Ozawa MG, Varner AS, Kasman IM, Chanthery YH, Pasqualini R, Arap W, McDonald DM. Antiangiogenic therapy decreases integrin expression in normalized tumor blood vessels. Cancer Research. 66: 2639-49. PMID 16510583 DOI: 10.1158/0008-5472.Can-05-1824 |
0.448 |
|
2006 |
Souza GR, Christianson DR, Staquicini FI, Ozawa MG, Snyder EY, Sidman RL, Miller JH, Arap W, Pasqualini R. Networks of gold nanoparticles and bacteriophage as biological sensors and cell-targeting agents. Proceedings of the National Academy of Sciences of the United States of America. 103: 1215-20. PMID 16434473 DOI: 10.1073/Pnas.0509739103 |
0.337 |
|
2006 |
Kolonin MG, Bover L, Sun J, Zurita AJ, Do KA, Lahdenranta J, Cardó-Vila M, Giordano RJ, Jaalouk DE, Ozawa MG, Moya CA, Souza GR, Staquicini FI, Kunyiasu A, Scudiero DA, ... ... Pasqualini R, et al. Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries. Cancer Research. 66: 34-40. PMID 16397212 DOI: 10.1158/0008-5472.Can-05-2748 |
0.782 |
|
2005 |
Oh Y, Mohiuddin I, Sun Y, Putnam JB, Hong WK, Arap W, Pasqualini R. Phenotypic Diversity of the Lung Vasculature in Experimental Models of Metastases Chest. 128: 5-6. PMID 16373855 DOI: 10.1378/Chest.128.6_Suppl.596S |
0.405 |
|
2005 |
Giordano RJ, Anobom CD, Cardó-Vila M, Kalil J, Valente AP, Pasqualini R, Almeida FC, Arap W. Structural basis for the interaction of a vascular endothelial growth factor mimic peptide motif and its corresponding receptors. Chemistry & Biology. 12: 1075-83. PMID 16242650 DOI: 10.1016/J.Chembiol.2005.07.008 |
0.359 |
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2005 |
Lionakis MS, Lahdenranta J, Sun J, Liu W, Lewis RE, Albert ND, Pasqualini R, Arap W, Kontoyiannis DP. Development of a ligand-directed approach to study the pathogenesis of invasive aspergillosis. Infection and Immunity. 73: 7747-58. PMID 16239579 DOI: 10.1128/Iai.73.11.7747-7758.2005 |
0.392 |
|
2005 |
Ozawa MG, Yao VJ, Chanthery YH, Troncoso P, Uemura A, Varner AS, Kasman IM, Pasqualini R, Arap W, McDonald DM. Angiogenesis with pericyte abnormalities in a transgenic model of prostate carcinoma. Cancer. 104: 2104-15. PMID 16208706 DOI: 10.1002/Cncr.21436 |
0.345 |
|
2005 |
Yao VJ, Ozawa MG, Trepel M, Arap W, McDonald DM, Pasqualini R. Targeting Pancreatic Islets with Phage Display Assisted by Laser Pressure Catapult Microdissection American Journal of Pathology. 166: 625-636. PMID 15681844 DOI: 10.1016/S0002-9440(10)62283-3 |
0.395 |
|
2005 |
Harris LD, Arap MA, Pasqualini R, Arap W, Sabichi AL, Grossman HB. 606: Identification of AN43, a Tumor Associated Antigen Found in Bladder Cancer The Journal of Urology. 173: 165-166. DOI: 10.1016/S0022-5347(18)34846-8 |
0.366 |
|
2004 |
Vidal CI, Mintz PJ, Lu K, Ellis LM, Manenti L, Giavazzi R, Gershenson DM, Broaddus R, Liu J, Arap W, Pasqualini R. An HSP90-mimic peptide revealed by fingerprinting the pool of antibodies from ovarian cancer patients. Oncogene. 23: 8859-67. PMID 15480432 DOI: 10.1038/Sj.Onc.1208082 |
0.423 |
|
2004 |
Arap MA, Lahdenranta J, Mintz PJ, Hajitou A, Sarkis ÁS, Arap W, Pasqualini R. Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands Cancer Cell. 6: 275-284. PMID 15380518 DOI: 10.1016/J.Ccr.2004.08.018 |
0.532 |
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2004 |
Chen L, Zurita AJ, Ardelt PU, Giordano RJ, Arap W, Pasqualini R. Design and validation of a bifunctional ligand display system for receptor targeting. Chemistry & Biology. 11: 1081-91. PMID 15324809 DOI: 10.1016/J.Chembiol.2004.05.019 |
0.478 |
|
2004 |
Arap W, Pasqualini R. Engineered embryonic endothelial progenitor cells as therapeutic Trojan horses Cancer Cell. 5: 406-408. PMID 15144946 DOI: 10.1016/S1535-6108(04)00121-7 |
0.404 |
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2004 |
Kolonin MG, Saha PK, Chan L, Pasqualini R, Arap W. Reversal of obesity by targeted ablation of adipose tissue. Nature Medicine. 10: 625-632. PMID 15133506 DOI: 10.1038/Nm1048 |
0.34 |
|
2004 |
Marchiò S, Lahdenranta J, Schlingemann RO, Valdembri D, Wesseling P, Arap MA, Hajitou A, Ozawa MG, Trepel M, Giordano RJ, Nanus DM, Dijkman HB, Oosterwijk E, Sidman RL, Cooper MD, ... ... Pasqualini R, et al. Aminopeptidase A is a functional target in angiogenic blood vessels. Cancer Cell. 5: 151-62. PMID 14998491 DOI: 10.1016/S1535-6108(04)00025-X |
0.442 |
|
2004 |
Zurita AJ, Troncoso P, Cardó-Vila M, Logothetis CJ, Pasqualini R, Arap W. Combinatorial screenings in patients: The interleukin-11 receptor α as a candidate target in the progression of human prostate cancer Cancer Research. 64: 435-439. PMID 14744752 DOI: 10.1158/0008-5472.Can-03-2675 |
0.378 |
|
2004 |
Sokolov K, Aaron J, Hsu B, Nida D, Gillenwater A, Follen M, MacAulay C, Adler-Storthz K, Korgel B, Descour M, Pasqualini R, Arap W, Lam W, Richards-Kortum R. Optical systems for in vivo molecular imaging of cancer. Technology in Cancer Research & Treatment. 2: 491-504. PMID 14640761 DOI: 10.1177/153303460300200602 |
0.307 |
|
2004 |
Zurita AJ, Hajitou A, Cardó-Vila M, Troncoso P, Logothetis CJ, Pasqualini R, Arap W. Preclinical development of an interleukin-11 receptor-targeted pro-apoptotic peptide against advanced prostate cancer Journal of Clinical Oncology. 22: 3190-3190. DOI: 10.1200/Jco.2004.22.90140.3190 |
0.369 |
|
2003 |
Zurita AJ, Arap W, Pasqualini R. Mapping tumor vascular diversity by screening phage display libraries. Journal of Controlled Release. 91: 183-186. PMID 12932650 DOI: 10.1016/S0168-3659(03)00236-0 |
0.52 |
|
2003 |
Müller OJ, Kaul F, Weitzman MD, Pasqualini R, Arap W, Kleinschmidt JA, Trepel M. Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors. Nature Biotechnology. 21: 1040-6. PMID 12897791 DOI: 10.1038/Nbt856 |
0.456 |
|
2003 |
Cardó-Vila M, Arap W, Pasqualini R. αvβ5 Integrin-Dependent Programmed Cell Death Triggered by a Peptide Mimic of Annexin V Molecular Cell. 11: 1151-1162. PMID 12769841 DOI: 10.1016/S1097-2765(03)00138-2 |
0.35 |
|
2003 |
Ellerby HM, Lee S, Ellerby LM, Chen S, Kiyota T, Del Rio G, Sugihara G, Sun Y, Bredesen DE, Arap W, Pasqualini R. An artificially designed pore-forming protein with anti-tumor effects Journal of Biological Chemistry. 278: 35311-35316. PMID 12750379 DOI: 10.1074/Jbc.M300474200 |
0.336 |
|
2003 |
Ardelt PU, Wood CG, Chen L, Mintz PJ, Moya C, Arap MA, Wright KC, Pasqualini R, Arap W. Targeting urothelium: ex vivo assay standardization and selection of internalizing ligands. The Journal of Urology. 169: 1535-40. PMID 12629410 DOI: 10.1097/01.Ju.0000055477.37115.66 |
0.771 |
|
2003 |
Tamm I, Trepel M, Cardó-Vila M, Sun Y, Welsh K, Cabezas E, Swatterthwait A, Arap W, Reed JC, Pasqualini R. Peptides targeting caspase inhibitors. The Journal of Biological Chemistry. 278: 14401-5. PMID 12538646 DOI: 10.1074/Jbc.M210133200 |
0.383 |
|
2003 |
Mintz PJ, Kim J, Do KA, Wang X, Zinner RG, Cristofanilli M, Arap MA, Hong WK, Troncoso P, Logothetis CJ, Pasqualini R, Arap W. Fingerprinting the circulating repertoire of antibodies from cancer patients Nature Biotechnology. 21: 57-63. PMID 12496764 DOI: 10.1038/Nbt774 |
0.411 |
|
2002 |
Pasqualini R, Arap W, McDonald DM. Probing the structural and molecular diversity of tumor vasculature. Trends in Molecular Medicine. 8: 563-571. PMID 12470989 DOI: 10.1016/S1471-4914(02)02429-2 |
0.494 |
|
2002 |
Pasqualini R, Barbas CF, Arap W. Vessel maneuvers: zinc fingers promote angiogenesis. Nature Medicine. 8: 1353-1354. PMID 12457173 DOI: 10.1038/Nm1202-1353 |
0.324 |
|
2002 |
Kolonin MG, Pasqualini R, Arap W. Teratogenicity induced by targeting a placental immunoglobulin transporter. Proceedings of the National Academy of Sciences of the United States of America. 99: 13055-13060. PMID 12242328 DOI: 10.1073/Pnas.162468499 |
0.353 |
|
2002 |
Trepel M, Arap W, Pasqualini R. In vivo phage display and vascular heterogeneity: implications for targeted medicine. Current Opinion in Chemical Biology. 6: 399-404. PMID 12023122 DOI: 10.1016/S1367-5931(02)00336-8 |
0.447 |
|
2002 |
Arap W, Haedicke W, Bernasconi M, Kain R, Rajotte D, Krajewski S, Ellerby HM, Bredesen DE, Pasqualini R, Ruoslahti E. Targeting the prostate for destruction through a vascular address Proceedings of the National Academy of Sciences of the United States of America. 99: 1527-1531. PMID 11830668 DOI: 10.1073/Pnas.241655998 |
0.34 |
|
2002 |
Arap W, Kolonin MG, Trepel M, Lahdenranta J, Cardó-Vila M, Giordano RJ, Mintz PJ, Ardelt PU, Yao VJ, Vidal CI, Chen L, Flamm A, Valtanen H, Weavind LM, Hicks ME, ... ... Pasqualini R, et al. Steps toward mapping the human vasculature by phage display. Nature Medicine. 8: 121-7. PMID 11821895 DOI: 10.1038/Nm0202-121 |
0.434 |
|
2001 |
Cardó-Vila M, Arden KC, Cavenee WK, Pasqualini R, Arap W. Is annexin 7 a tumor suppressor gene in prostate cancer? The Pharmacogenomics Journal. 1: 92-4. PMID 11911446 DOI: 10.1038/Sj.Tpj.6500028 |
0.335 |
|
2001 |
Gerlag DM, Borges E, Tak PP, Ellerby HM, Bredesen DE, Pasqualini R, Ruoslahti E, Firestein GS. Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature Arthritis Research. 3: 357-361. PMID 11714389 DOI: 10.1186/Ar327 |
0.374 |
|
2001 |
Giordano RJ, Cardó-Vila M, Lahdenranta J, Pasqualini R, Arap W. Biopanning and rapid analysis of selective interactive ligands. Nature Medicine. 7: 1249-1253. PMID 11689892 DOI: 10.1038/Nm1101-1249 |
0.402 |
|
2001 |
Kolonin M, Pasqualini R, Arap W. Molecular addresses in blood vessels as targets for therapy. Current Opinion in Chemical Biology. 5: 308-313. PMID 11479123 DOI: 10.1016/S1367-5931(00)00207-6 |
0.491 |
|
2001 |
Pasqualini R, McDonald DM, Arap W. Vascular targeting and antigen presentation. Nature Immunology. 2: 567-568. PMID 11429533 DOI: 10.1038/89704 |
0.388 |
|
2001 |
Grifman M, Trepel M, Speece P, Gilbert LB, Arap W, Pasqualini R, Weitzman MD. Incorporation of tumor-targeting peptides into recombinant adeno-associated virus capsids. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 964-75. PMID 11407911 DOI: 10.1006/Mthe.2001.0345 |
0.499 |
|
2000 |
Trepel M, Arap W, Pasqualini R. Exploring vascular heterogeneity for gene therapy targeting. Gene Therapy. 7: 2059-2060. PMID 11223985 DOI: 10.1038/Sj.Gt.3301361 |
0.331 |
|
2000 |
Ogawa K, Pasqualini R, Lindberg RA, Kain R, Freeman AL, Pasquale EB. The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization. Oncogene. 19: 6043-52. PMID 11146556 DOI: 10.1038/Sj.Onc.1204004 |
0.432 |
|
2000 |
Trepel M, Grifman M, Weitzman MD, Pasqualini R. Molecular adaptors for vascular-targeted adenoviral gene delivery Human Gene Therapy. 11: 1971-1981. PMID 11020797 DOI: 10.1089/10430340050143408 |
0.443 |
|
1999 |
Ellerby HM, Arap W, Ellerby LM, Kain R, Andrusiak R, Rio GD, Krajewski S, Lombardo CR, Rao R, Ruoslahti E, Bredesen DE, Pasqualini R. Anti-cancer activity of targeted pro-apoptotic peptides Nature Medicine. 5: 1032-1038. PMID 10470080 DOI: 10.1038/12469 |
0.445 |
|
1999 |
Koivunen E, Arap W, Valtanen H, Rainisalo A, Medina OP, Heikkilä P, Kantor C, Gahmberg CG, Salo T, Konttinen YT, Sorsa T, Ruoslahti E, Pasqualini R. Tumor targeting with a selective gelatinase inhibitor Nature Biotechnology. 17: 768-774. PMID 10429241 DOI: 10.1038/11703 |
0.419 |
|
1998 |
Arap W, Pasqualini R, Ruoslahti E. Chemotherapy targeted to tumor vasculature Current Opinion in Oncology. 10: 560-565. PMID 9818236 DOI: 10.1097/00001622-199811000-00014 |
0.43 |
|
1998 |
Rajotte D, Arap W, Hagedorn M, Koivunen E, Pasqualini R, Ruoslahti E. Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display. Journal of Clinical Investigation. 102: 430-437. PMID 9664085 DOI: 10.1172/Jci3008 |
0.419 |
|
1998 |
Arap W, Pasqualini R, Ruoslahti E. Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model Science. 279: 377-380. PMID 9430587 DOI: 10.1126/Science.279.5349.377 |
0.475 |
|
1997 |
Pasqualini R, Koivunen E, Ruoslahti E. αv Integrins as receptors for tumor targeting by circulating ligands Nature Biotechnology. 15: 542-546. PMID 9181576 DOI: 10.1038/Nbt0697-542 |
0.488 |
|
1996 |
Pasqualini R, Bourdoulous S, Koivunen E, Woods VL, Ruoslahti E. A polymeric form of fibronectin has antimetastatic effects against multiple tumor types. Nature Medicine. 2: 1197-1203. PMID 8898745 DOI: 10.1038/Nm1196-1197 |
0.412 |
|
1996 |
Pasqualini R, Ruoslahti E. Organ targeting in vivo using phage display peptide libraries Nature. 380: 364-366. PMID 8598934 DOI: 10.1038/380364A0 |
0.421 |
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