Josef M. Kurtz, Ph.D. - Publications

Affiliations: 
2002 Harvard University, Cambridge, MA, United States 
Area:
Immunology

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Leonard DA, Powell HR, Defazio MW, Shanmugarajah K, Mastroianni M, Rosales I, Farkash EA, Colvin RB, Randolph MA, Sachs DH, Kurtz JM, Cetrulo CL. Cutaneous leukocyte lineages in tolerant large animal and immunosuppressed clinical vascularized composite allograft recipients. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 32741100 DOI: 10.1111/Ajt.16230  0.519
2017 Mastroianni M, Ng ZY, Goyal R, Mallard C, Farkash EA, Leonard DA, Albritton A, Shanmugarajah K, Kurtz JM, Sachs DH, Macri LK, Kohn J, Cetrulo CL. Topical Delivery of Immunosuppression to Prolong Xenogeneic and Allogeneic Split-Thickness Skin Graft Survival. Journal of Burn Care & Research : Official Publication of the American Burn Association. PMID 28639977 DOI: 10.1097/Bcr.0000000000000597  0.375
2017 Leonard DA, Mallard C, Albritton A, Torabi R, Mastroianni M, Sachs DH, Kurtz JM, Cetrulo CL. Skin grafts from genetically modified α-1,3-galactosyltransferase knockout miniature swine: A functional equivalent to allografts. Burns : Journal of the International Society For Burn Injuries. PMID 28602591 DOI: 10.1016/J.Burns.2017.04.026  0.357
2017 Cetrulo CL, Li K, Salinas HM, Treiser MD, Schol I, Barrisford GW, McGovern FJ, Feldman AS, Grant MT, Tanrikut C, Lee JH, Ehrlichman RJ, Holzer PW, Choy GM, Liu RW, ... ... Kurtz JM, et al. Penis Transplantation: First US Experience. Annals of Surgery. PMID 28509699 DOI: 10.1097/Sla.0000000000002241  0.4
2017 Lellouch AG, Ng ZY, Rosales IA, Colvin RB, Gama A, Schol IM, Geoghegan L, Kurtz JM, Cetrulo CL. Abstract 47: Delayed Tolerance Induction Protocol for Vascularized Composite Allografts in Non-Human Primates Plastic and Reconstructive Surgery. Global Open. 5: 36-37. DOI: 10.1097/01.Gox.0000516567.40845.Df  0.309
2016 Shanmugarajah K, Powell H, Leonard DA, Mallard C, Albritton A, Harrington E, Randolph MA, Farkash E, Sachs DH, Kurtz JM, Cetrulo CL. The Effect of MHC Antigen Matching Between Donors and Recipients on Skin Tolerance of Vascularized Composite Allografts. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28035752 DOI: 10.1111/Ajt.14189  0.48
2016 Lellouch AG, Ng ZY, Kurtz JM, Cetrulo CL. Mixed Chimerism-Based Regimens in VCA Current Transplantation Reports. 3: 390-394. DOI: 10.1007/S40472-016-0124-7  0.459
2015 Madariaga ML, Michel SG, La Muraglia GM, Sekijima M, Villani V, Leonard DA, Powell HJ, Kurtz JM, Farkash EA, Colvin RB, Allan JS, Cetrulo CL, Huang CA, Sachs DH, Yamada K, et al. Kidney-induced cardiac allograft tolerance in miniature swine is dependent on MHC-matching of donor cardiac and renal parenchyma. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 15: 1580-90. PMID 25824550 DOI: 10.1111/Ajt.13131  0.385
2015 Leto Barone AA, Mastroianni M, Farkash EA, Mallard C, Albritton A, Torabi R, Leonard DA, Kurtz JM, Sachs DH, Cetrulo CL. Genetically modified porcine split-thickness skin grafts as an alternative to allograft for provision of temporary wound coverage: preliminary characterization. Burns : Journal of the International Society For Burn Injuries. 41: 565-74. PMID 25406888 DOI: 10.1016/J.Burns.2014.09.003  0.404
2015 Leonard DA, Shanmugarajah K, Powell H, Albritton A, Mallard C, Sachs DH, Cetrulo CL, Kurtz JM. Abstract 10: The Role of Skin-Specific Immunobiology and Major Histocompatibility Complex Sharing in Vascularized Composite Allograft Tolerance Plastic and Reconstructive Surgery. 135: 17. DOI: 10.1097/01.Prs.0000465458.37717.94  0.339
2015 Leto Barone AA, Kurtz JM, Albritton A, Mallard CA, Shanmugarajah K, Torabi R, Leonard DA, Randolph MA, Huang CA, Sachs DH, Cetrulo CL. Effects of Transient Donor Chimerism on Rejection of MHC-Mismatched Vascularized Composite Allografts in Swine Vascularized Composite Allotransplantation. 2: 1-8. DOI: 10.1080/23723505.2015.1039692  0.32
2014 Shanmugarajah K, Mallard C, Leonard DA, Albritton A, Powell H, Harrington E, Randolph MA, Sachs DH, Kurtz JM, Cetrulo CL. Abstract 104: MHC class I sharing influences the fate of the epidermal component of vascularized composite allografts in mixed chimerism based tolerance protocols in miniature Swine. Plastic and Reconstructive Surgery. 133: 119. PMID 25942215 DOI: 10.1097/01.Prs.0000444928.61077.5D  0.335
2014 Chadha R, Leonard DA, Kurtz JM, Cetrulo CL. The unique immunobiology of the skin: implications for tolerance of vascularized composite allografts. Current Opinion in Organ Transplantation. 19: 566-72. PMID 25333830 DOI: 10.1097/Mot.0000000000000136  0.424
2014 Tena A, Kurtz J, Leonard DA, Dobrinsky JR, Terlouw SL, Mtango N, Verstegen J, Germana S, Mallard C, Arn JS, Sachs DH, Hawley RJ. Transgenic expression of human CD47 markedly increases engraftment in a murine model of pig-to-human hematopoietic cell transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 2713-22. PMID 25278264 DOI: 10.1111/Ajt.12918  0.538
2014 Leonard DA, Kurtz JM, Cetrulo CL. Achieving immune tolerance in hand and face transplantation: a realistic prospect? Immunotherapy. 6: 499-502. PMID 24896618 DOI: 10.2217/Imt.14.29  0.503
2014 Albritton A, Leonard DA, Leto Barone A, Keegan J, Mallard C, Sachs DH, Kurtz JM, Cetrulo CL. Lack of cross-sensitization between α-1,3-galactosyltransferase knockout porcine and allogeneic skin grafts permits serial grafting. Transplantation. 97: 1209-15. PMID 24798308 DOI: 10.1097/Tp.0000000000000093  0.368
2014 Leonard DA, Kurtz JM, Mallard C, Albritton A, Duran-Struuck R, Farkash EA, Crepeau R, Matar A, Horner BM, Randolph MA, Sachs DH, Huang CA, Cetrulo CL. Vascularized composite allograft tolerance across MHC barriers in a large animal model American Journal of Transplantation. 14: 343-355. PMID 24405666 DOI: 10.1111/Ajt.12560  0.535
2014 Shanmugarajah K, Leonard DA, Mallard C, Powell H, Albritton A, Randolph M, Harrington E, Sachs DH, Kurtz JM, Cetrulo CL. MHC Class I Matching Between Donors and Recipients Influences the Skin Tolerance of Vascularized Composite Allografts Vascularized Composite Allotransplantation. 1: 68-68. DOI: 10.4161/23723505.2014.970912  0.332
2014 Mastroianni M, Mallard CA, Albritton A, Leonard DA, Kurtz JM, Sachs DH, Cetrulo CL. Abstract P21: Topical Immunosuppression Does Not Prolong Xenogeneic Skin Graft Survival Plastic and Reconstructive Surgery. 133: 1038-1039. DOI: 10.1097/01.Prs.0000445867.58427.D6  0.354
2014 Powell H, Leonard DA, Albritton A, Mallard C, Cetrulo CL, Kurtz JM. Abstract P16: Detailed Characterization and Functional Analysis of Skin-Resident Leukocytes from Vascularized Composite Allografts in Tolerant Miniature Swine Mixed Chimeras Plastic and Reconstructive Surgery. 133: 198-199. DOI: 10.1097/01.Prs.0000445013.48989.C4  0.321
2013 Leonard DA, Kurtz JM, Cetrulo CL. Vascularized composite allotransplantation: towards tolerance and the importance of skin-specific immunobiology. Current Opinion in Organ Transplantation. 18: 645-51. PMID 24126805 DOI: 10.1097/Mot.0000000000000022  0.332
2012 Leonard DA, McGrouther DA, Kurtz JM, Cetrulo CL. Tolerance induction strategies in vascularized composite allotransplantation: mixed chimerism and novel developments. Clinical & Developmental Immunology. 2012: 863264. PMID 23320020 DOI: 10.1155/2012/863264  0.444
2012 Leonard D, Albritton A, Barone AL, Torabi R, Mallard C, Kurtz J, Sachs D, Cetrulo C. Abstract 21P: Lack of Cross-Sensitization Between Alpha-1, 3-Galactosyltransferase Knockout Porcine and Allogeneic Skin Grafts Permits Serial Grafting and Extended Temporary Coverage of Simulated Burn Wounds Plastic and Reconstructive Surgery. 130: 94. DOI: 10.1097/01.Prs.0000416219.21153.D8  0.334
2012 Leonard D, Torabi R, Mallard C, Albritton A, Randolph M, Kurtz J, Sachs D, Cetrulo C. Abstract 20P: Prolonged Vascularized Composite Allograft Survival and Multi-Lineage Mixed Chimerism Across A Full Major Histocompatibility Barrier in Swine Plastic and Reconstructive Surgery. 130: 93. DOI: 10.1097/01.Prs.0000416218.26990.80  0.318
2012 Leonard D, Horner B, Randolph M, Duran-Struuck R, Crepeau R, Mallard C, Matar A, Albritton A, Kurtz J, Sachs D, Huang C, Cetrulo C. Abstract 110: Induction of Skin Tolerance by Establishment of Stable Mixed Chimerism Across A Major Histocompatibility Barrier in Miniature Swine Plastic and Reconstructive Surgery. 130: 80. DOI: 10.1097/01.Prs.0000416194.98487.C8  0.334
2012 Barone AL, Torabi R, Randolph M, Leonard D, Mallard C, Albritton A, Duran-Struuck R, Matar A, Crepeau R, Tang Y, Scalea J, Wang Z, Tena A, Hawley R, Kurtz J, et al. Abstract 37: Vascularized Composite Allograft Transplantation and Mixed Hematopoietic Chimerism Across a Full MHC Barrier in Swine Plastic and Reconstructive Surgery. 130: 36. DOI: 10.1097/01.Prs.0000416125.23144.A8  0.458
2011 del Rio ML, Kurtz J, Perez-Martinez C, Ghosh A, Perez-Simon JA, Rodriguez-Barbosa JI. B- and T-lymphocyte attenuator targeting protects against the acute phase of graft versus host reaction by inhibiting donor anti-host cytotoxicity. Transplantation. 92: 1085-93. PMID 21978997 DOI: 10.1097/Tp.0B013E3182339D4A  0.471
2011 LoCascio SA, Spinelli J, Kurtz J. Hematopoietic stem cell transplantation for the treatment of autoimmunity in type 1 diabetes. Current Stem Cell Research & Therapy. 6: 29-37. PMID 20955158 DOI: 10.2174/157488811794480681  0.438
2011 Barone AAL, Torabi R, Randolph MA, Leonard DA, Mallard C, Albritton A, Duran-Struuck R, Matar A, Crepeau R, Tang Y, Scalea JR, Wang Z, Tena A, Hawley RJ, Kurtz JM, et al. Lop10: Vascularized Composite Allograft Transplantation And Mixed Hematopoietic Chimerism Across A Full Mhc Barrier In Swine: Preliminary Results Plastic and Reconstructive Surgery. 128: 618. DOI: 10.1097/01.Prs.0000400363.55026.A7  0.461
2010 Mollov JL, Lucas CL, Haspot F, Kurtz J, Gaspar C, Guzman A, Sykes M. Recipient dendritic cells, but not B cells, are required antigen-presenting cells for peripheral alloreactive CD8+ T-cell tolerance. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 10: 518-26. PMID 20121730 DOI: 10.1111/J.1600-6143.2009.02967.X  0.777
2010 Fehr T, Lucas CL, Kurtz J, Onoe T, Zhao G, Hogan T, Vallot C, Rao A, Sykes M. A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo. Blood. 115: 1280-7. PMID 20007805 DOI: 10.1182/Blood-2009-07-230680  0.771
2010 Spinelli J, Sykes M, Kurtz J. Reversal of Autoimmunity by Induction of Mixed Hematopoietic Chimerism: Evidence for Non-deletional Mechanisms Clinical Immunology. 135: S91. DOI: 10.1016/J.Clim.2010.03.272  0.498
2009 Kurtz J, Raval F, Vallot C, Der J, Sykes M. CTLA-4 on alloreactive CD4 T cells interacts with recipient CD80/86 to promote tolerance. Blood. 113: 3475-84. PMID 19179471 DOI: 10.1182/Blood-2008-01-133736  0.691
2008 Fehr T, Wang S, Haspot F, Kurtz J, Blaha P, Hogan T, Chittenden M, Wekerle T, Sykes M. Rapid deletional peripheral CD8 T cell tolerance induced by allogeneic bone marrow: role of donor class II MHC and B cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 4371-80. PMID 18768896 DOI: 10.4049/Jimmunol.181.6.4371  0.701
2008 Camirand G, Stéphan L, Rousseau J, Sackett MK, Caron NJ, Mills P, Kurtz J, Sykes M, Rothstein DM, Tremblay JP. Central tolerance to myogenic cell transplants does not include muscle neoantigens. Transplantation. 85: 1791-801. PMID 18580473 DOI: 10.1097/Tp.0B013E31817726Bc  0.564
2008 Kurtz J, Shubert L, LoCascio S, Sykes M. INDUCTION OF ALLOREACTIVE CD4 TOLERANCE BY CROSS-PRESENTATION OF DONOR MHC MOLECULES BY RECIPIENT APCʼ Transplantation. 86: 228-229. DOI: 10.1097/01.Tp.0000332177.47191.33  0.647
2005 Fehr T, Takeuchi Y, Kurtz J, Wekerle T, Sykes M. Early regulation of CD8 T cell alloreactivity by CD4+CD25- T cells in recipients of anti-CD154 antibody and allogeneic BMT is followed by rapid peripheral deletion of donor-reactive CD8+ T cells, precluding a role for sustained regulation. European Journal of Immunology. 35: 2679-90. PMID 16082727 DOI: 10.1002/Eji.200526190  0.685
2005 Domenig C, Sanchez-Fueyo A, Kurtz J, Alexopoulos SP, Mariat C, Sykes M, Strom TB, Zheng XX. Roles of deletion and regulation in creating mixed chimerism and allograft tolerance using a nonlymphoablative irradiation-free protocol. Journal of Immunology (Baltimore, Md. : 1950). 175: 51-60. PMID 15972631 DOI: 10.4049/Jimmunol.175.1.51  0.646
2004 Kurtz J, Wekerle T, Sykes M. Tolerance in mixed chimerism - a role for regulatory cells? Trends in Immunology. 25: 518-23. PMID 15364053 DOI: 10.1016/J.It.2004.08.007  0.624
2004 Kurtz J, Shaffer J, Lie A, Anosova N, Benichou G, Sykes M. Mechanisms of early peripheral CD4 T-cell tolerance induction by anti-CD154 monoclonal antibody and allogeneic bone marrow transplantation: evidence for anergy and deletion but not regulatory cells. Blood. 103: 4336-43. PMID 14962909 DOI: 10.1182/Blood-2003-08-2642  0.721
2004 Takeuchi Y, Ito H, Kurtz J, Wekerle T, Ho L, Sykes M. Earlier low-dose TBI or DST overcomes CD8+ T-cell-mediated alloresistance to allogeneic marrow in recipients of anti-CD40L. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 4: 31-40. PMID 14678032 DOI: 10.1046/J.1600-6135.2003.00272.X  0.71
2004 Kurtz J, Lie A, Griffith M, Eysaman S, Shaffer J, Anosova N, Turka L, Benichou G, Sykes M. Lack of role for CsA-sensitive or Fas pathways in the tolerization of CD4 T cells via BMT and anti-CD40L. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 3: 804-16. PMID 12814472 DOI: 10.1034/J.1600-6143.2003.00128.X  0.715
2004 Ito H, Kurtz J, Shaffer J, Sykes M. ANTI-CD40L MAB OVERCOMES CD4 T CELL-MEDIATED RESISTANCE TO XENOGENEIC MARROW ENGRAFTMENT Transplantation. 78: 156-157. DOI: 10.1097/00007890-200407271-00413  0.644
2004 Fehr T, Takeuchi Y, Kurtz J, Sykes M. CD8+ T CELL TOLERANCE AFTER BONE MARROW TRANSPLANTATION USING NON-MYELOABLATIVE CONDITIONING WITH TBI AND ANTI-CD154 MAB: IMPORTANCE OF SIGNAL 1, CD4+ T CELLS AND CTLA4, BUT NO EVIDENCE FOR LONG-TERM REGULATION Transplantation. 78: 41. DOI: 10.1097/00007890-200407271-00120  0.692
2003 Wekerle T, Kurtz J, Bigenzahn S, Takeuchi Y, Sykes M. Mechanisms of transplant tolerance induction using costimulatory blockade. Current Opinion in Immunology. 14: 592-600. PMID 12183158 DOI: 10.1016/S0952-7915(02)00378-3  0.592
2002 Blaha P, Bigenzahn S, Koporc Z, Schmid M, Langer F, Selzer E, Bergmeister H, Wrba F, Kurtz J, Kiss C, Roth E, Muehlbacher F, Sykes M, Wekerle T. The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade. Blood. 101: 2886-93. PMID 12433677 DOI: 10.1182/Blood-2002-10-3014  0.646
2002 Kurtz J, Ito H, Wekerle T, Shaffer J, Sykes M. Mechanisms involved in the establishment of tolerance through costimulatory blockade and BMT: lack of requirement for CD40L-mediated signaling for tolerance or deletion of donor-reactive CD4+ cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 1: 339-49. PMID 12099378 DOI: 10.1034/J.1600-6143.2001.10409.X  0.735
2002 Blaha P, Kiss C, Langer F, Selzer E, Bergmeister H, Kurtz J, Roth E, Muehlbacher F, Sykes M, Wekerle T. The effects of rapamycin and cyclosporin a on tolerance induction through bone marrow transplantation with costimulation blockade Journal of Heart and Lung Transplantation. 21: 155. DOI: 10.1016/S1053-2498(01)00712-4  0.615
2001 Ito H, Kurtz J, Shaffer J, Sykes M. CD4 T cell-mediated alloresistance to fully MHC-mismatched allogeneic bone marrow engraftment is dependent on CD40-CD40 ligand interactions, and lasting T cell tolerance is induced by bone marrow transplantation with initial blockade of this pathway. Journal of Immunology (Baltimore, Md. : 1950). 166: 2970-81. PMID 11207246 DOI: 10.4049/Jimmunol.166.5.2970  0.708
2001 Wekerle T, Kurtz J, Sayegh M, Ito H, Wells A, Bensinger S, Shaffer J, Turka L, Sykes M. Peripheral deletion after bone marrow transplantation with costimulatory blockade has features of both activation-induced cell death and passive cell death. Journal of Immunology (Baltimore, Md. : 1950). 166: 2311-6. PMID 11160287 DOI: 10.4049/Jimmunol.166.4.2311  0.655
2000 Wekerle T, Kurtz J, Ito H, Ronquillo JV, Dong V, Zhao G, Shaffer J, Sayegh MH, Sykes M. Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment. Nature Medicine. 6: 464-9. PMID 10742157 DOI: 10.1038/74731  0.646
2000 Ito H, Kurtz J, Shaffer J, Sykes M. ONE INJECTION OF ANTI-CD40L MAB OVERCOMES CD4 T CELL-MEDIATED RESISTANCE TO FULLY MHC-MISMATCHED ALLOGENEIC MARROW ENGRAFTMENT. Transplantation. 69: S371. DOI: 10.1097/00007890-200004271-00995  0.657
2000 Wekerle T, Kurtz J, Ito H, Shaffer J, Sykes M. A ONE-DAY PROTOCOL OF BONE MARROW TRANSPLANTATION WITH COSTIMULATORY BLOCKADE FOR THE RAPID INDUCTION OF DONOR-SPECIFIC SKIN GRAFT TOLERANCE WITHOUT PRE-CONDITIONING. Transplantation. 69: S370. DOI: 10.1097/00007890-200004271-00994  0.609
2000 Kurtz J, Ito H, Shaffer J, Sykes M. SYNERGISTIC EFFECT OF COSTIMULATORY BLOCKADE AND CYCLOSPORIN TREATMENT IN THE ESTABLISHMENT OF EARLY MIXED HEMATAPOIETIC CHIMERISM. Transplantation. 69: S370. DOI: 10.1097/00007890-200004271-00993  0.458
1999 Wekerle T, Kurtz J, Sykes M. Mixed hematopoietic chimerism and transplantation tolerance: insights from experimental models Current Opinion in Organ Transplantation. 4: 44. DOI: 10.1097/00075200-199903000-00009  0.587
1999 Wekerle T, Turka LA, Sayegh MH, Kurtz J, Ito H, Wells AD, Shaffer J, Sykes M. EARLY DELETION AFTER BONE MARROW TRANSPLANTATION WITH COSTIMULATORY BLOCKADE IS FAS-DEPENDENT AND IS PREVENTED BY BCL-XL OVEREXPRESSION Transplantation. 67: S242. DOI: 10.1097/00007890-199904150-00965  0.571
1999 Kurtz J, Wekerle T, Ito H, Shaffer J, Sykes M. AN UNEXPECTED ROLE FOR CD28 AND LACK OF A ROLE FOR CD40L SIGNALING IN PERIPHERAL DELETION OF DONOR-REACTIVE CD4+ T CELLS AND ESTABLISHMENT OF MIXED CHIMERISM THROUGH COSTIMULATORY BLOCKADE Transplantation. 67: S120. DOI: 10.1097/00007890-199904150-00481  0.658
1999 Wekerle T, Sayegh MH, Kurtz J, Ronquillo JV, Dong V, Swenson KG, Zhao G, Sykes M. SUBSTANTIAL DONOR CHIMERISM AND TOLERANCE ACROSS A FULL MHC BARRIER WITHOUT HOST PRE-CONDITIONING Transplantation. 67: S34. DOI: 10.1097/00007890-199904150-00138  0.542
1999 Ito H, Wekerle T, Kurtz J, Sayegh MH, Hill J, Chandraker A, Pearson DA, Swenson KG, Zhao G, Sykes M. INDUCTION OF MIXED HEMATOPOIETIC CHIMERISM AND TOLERANCE WITH SUBOPTIMAL RECIPIENT T CELL DEPLETION, 3GY TBI AND ANTI-CD154 OR CTLA4Ig: TOWARD A CLINICAL REGIMEN USEFUL FOR CADAVERIC DONORS Transplantation. 67: S34. DOI: 10.1097/00007890-199904150-00137  0.701
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