| Year |
Citation |
Score |
| 2022 |
Aujla PK, Hu M, Hartley B, Kranrod J, Viveiros A, Kilic T, Owen CA, Oudit GY, Seubert JM, Julien O, Kassiri Z. Loss of ADAM15 Exacerbates Transition to Decompensated Myocardial Hypertrophy and Dilation Through Activation of the Calcineurin Pathway. Hypertension (Dallas, Tex. : 1979). PMID 36330793 DOI: 10.1161/HYPERTENSIONAHA.122.19411 |
0.317 |
|
| 2022 |
Nagalingam RS, Chattopadhyaya S, Al-Hattab DS, Cheung DYC, Schwartz LY, Jana S, Aroutiounova N, Ledingham DA, Moffatt TL, Landry NM, Bagchi RA, Dixon IMC, Wigle JT, Oudit GY, Kassiri Z, et al. Scleraxis and fibrosis in the pressure-overloaded heart. European Heart Journal. PMID 36200607 DOI: 10.1093/eurheartj/ehac362 |
0.31 |
|
| 2022 |
Chute M, Aujla PK, Li Y, Jana S, Zhabyeyev P, Rasmuson J, Owen CA, Abraham T, Oudit GY, Kassiri Z. ADAM15 is required for optimal collagen cross-linking and scar formation following myocardial infarction. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 34995785 DOI: 10.1016/j.matbio.2021.12.002 |
0.315 |
|
| 2021 |
Fan D, Kassiri Z. Modulation of Cardiac Fibrosis in and Beyond Cells. Frontiers in Molecular Biosciences. 8: 750626. PMID 34778374 DOI: 10.3389/fmolb.2021.750626 |
0.325 |
|
| 2021 |
Jana S, Aujla P, Hu M, Kilic T, Zhabyeyev P, McCulloch CA, Oudit GY, Kassiri Z. Gelsolin is an important mediator of Angiotensin II-induced activation of cardiac fibroblasts and fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21932. PMID 34549830 DOI: 10.1096/fj.202100038RR |
0.326 |
|
| 2020 |
Oh Y, Yang S, Liu X, Jana S, Izaddoustdar F, Gao X, Debi R, Kim DK, Kim KH, Yang P, Kassiri Z, Lakin R, Backx PH. Transcriptomic Bioinformatic Analyses of Atria Uncover Involvement of Pathways Related to Strain and Post-translational Modification of Collagen in Increased Atrial Fibrillation Vulnerability in Intensely Exercised Mice. Frontiers in Physiology. 11: 605671. PMID 33424629 DOI: 10.3389/fphys.2020.605671 |
0.69 |
|
| 2018 |
Patel VB, Zhabyeyev P, Chen X, Wang F, Paul M, Fan D, McLean BA, Basu R, Zhang P, Shah S, Dawson JF, Pyle WG, Hazra M, Kassiri Z, Hazra S, et al. PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease. Nature Communications. 9: 5390. PMID 30568254 DOI: 10.1038/s41467-018-07812-8 |
0.313 |
|
| 2018 |
Chen X, Zhabyeyev P, Azad AK, Wang W, Minerath RA, DesAulniers J, Grueter CE, Murray AG, Kassiri Z, Vanhaesebroeck B, Oudit GY. Endothelial and Cardiomyocyte PI3Kβ Divergently Regulate Cardiac Remodeling in Response to Ischemic Injury. Cardiovascular Research. PMID 30496354 DOI: 10.1093/Cvr/Cvy298 |
0.314 |
|
| 2014 |
Wang W, Patel VB, Parajuli N, Fan D, Basu R, Wang Z, Ramprasath T, Kassiri Z, Penninger JM, Oudit GY. Heterozygote loss of ACE2 is sufficient to increase the susceptibility to heart disease. Journal of Molecular Medicine (Berlin, Germany). 92: 847-58. PMID 24728465 DOI: 10.1007/S00109-014-1149-Y |
0.304 |
|
| 2014 |
Fan D, Takawale A, Basu R, Patel V, Lee J, Kandalam V, Wang X, Oudit GY, Kassiri Z. Differential role of TIMP2 and TIMP3 in cardiac hypertrophy, fibrosis, and diastolic dysfunction. Cardiovascular Research. 103: 268-80. PMID 24692173 DOI: 10.1093/cvr/cvu072 |
0.328 |
|
| 2013 |
Wang W, Patel V, Wang Z, Kassiri Z, Penninger J, Oudit G. Haploinsufficiency of ACE2 Is Sufficient to Enhance Susceptibility to Heart Failure With Adverse Cardiovascular Remodeling Canadian Journal of Cardiology. 29: S234-S235. DOI: 10.1016/J.Cjca.2013.07.378 |
0.367 |
|
| 2012 |
Fan D, Takawale A, Lee J, Kassiri Z. Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease. Fibrogenesis & Tissue Repair. 5: 15. PMID 22943504 DOI: 10.1186/1755-1536-5-15 |
0.313 |
|
| 2011 |
Guo D, Thiyam G, Bodiga S, Kassiri Z, Oudit GY. Uncoupling between enhanced excitation-contraction coupling and the response to heart disease: lessons from the PI3Kγ knockout murine model. Journal of Molecular and Cellular Cardiology. 50: 606-12. PMID 21276799 DOI: 10.1016/j.yjmcc.2011.01.011 |
0.332 |
|
| 2011 |
Bodiga S, JiuChang Z, Wang W, Basu R, Das S, Kassiri Z, Oudit G. 545 Cardioprotective effects mediated by AT1 receptor blockade and enhancing ang 1-7 in experimental heart failure in ACE2-null mice Canadian Journal of Cardiology. 27: S258-S259. DOI: 10.1016/J.Cjca.2011.07.453 |
0.372 |
|
| 2011 |
Mori J, Basu R, Zhang L, Wagg C, Kassiri Z, Lopaschuk G, Oudit G. 291 Angiotensin II induces diastolic dysfunction via the AT1 receptor with a reduction in carbohydrate oxidation caused by up-regulation of pyruvate dehydrogenase kinase 4 (PDK4) Canadian Journal of Cardiology. 27: S168-S169. DOI: 10.1016/J.Cjca.2011.07.219 |
0.306 |
|
| 2010 |
Guo D, Kassiri Z, Basu R, Chow FL, Kandalam V, Damilano F, Liang W, Izumo S, Hirsch E, Penninger JM, Backx PH, Oudit GY. Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress. Circulation Research. 107: 1275-89. PMID 20847309 DOI: 10.1161/Circresaha.110.229054 |
0.627 |
|
| 2010 |
Kandalam V, Basu R, Abraham T, Wang X, Awad A, Wang W, Lopaschuk GD, Maeda N, Oudit GY, Kassiri Z. Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1012-23. PMID 20675565 DOI: 10.1152/Ajpheart.00246.2010 |
0.31 |
|
| 2010 |
Koskivirta I, Kassiri Z, Rahkonen O, Kiviranta R, Oudit GY, McKee TD, Kytö V, Saraste A, Jokinen E, Liu PP, Vuorio E, Khokha R. Mice with tissue inhibitor of metalloproteinases 4 (Timp4) deletion succumb to induced myocardial infarction but not to cardiac pressure overload. The Journal of Biological Chemistry. 285: 24487-93. PMID 20516072 DOI: 10.1074/Jbc.M110.136820 |
0.312 |
|
| 2009 |
Basu R, Oudit GY, Wang X, Zhang L, Ussher JR, Lopaschuk GD, Kassiri Z. Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function. American Journal of Physiology. Heart and Circulatory Physiology. 297: H2096-108. PMID 19801494 DOI: 10.1152/ajpheart.00452.2009 |
0.331 |
|
| 2009 |
Kassiri Z, Defamie V, Hariri M, Oudit GY, Anthwal S, Dawood F, Liu P, Khokha R. Simultaneous transforming growth factor beta-tumor necrosis factor activation and cross-talk cause aberrant remodeling response and myocardial fibrosis in Timp3-deficient heart. The Journal of Biological Chemistry. 284: 29893-904. PMID 19625257 DOI: 10.1074/Jbc.M109.028449 |
0.399 |
|
| 2009 |
Wang X, Oka T, Chow FL, Cooper SB, Odenbach J, Lopaschuk GD, Kassiri Z, Fernandez-Patron C. Tumor necrosis factor-alpha-converting enzyme is a key regulator of agonist-induced cardiac hypertrophy and fibrosis. Hypertension. 54: 575-82. PMID 19581512 DOI: 10.1161/Hypertensionaha.108.127670 |
0.309 |
|
| 2008 |
Oudit GY, Kassiri Z, Zhou J, Liu QC, Liu PP, Backx PH, Dawood F, Crackower MA, Scholey JW, Penninger JM. Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress. Cardiovascular Research. 78: 505-14. PMID 18281373 DOI: 10.1093/Cvr/Cvn041 |
0.523 |
|
| 2007 |
Oudit GY, Kassiri Z. Role of PI3 kinase gamma in excitation-contraction coupling and heart disease. Cardiovascular & Hematological Disorders Drug Targets. 7: 295-304. PMID 18220729 |
0.306 |
|
| 2007 |
Wong DW, Oudit GY, Reich H, Kassiri Z, Zhou J, Liu QC, Backx PH, Penninger JM, Herzenberg AM, Scholey JW. Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury. The American Journal of Pathology. 171: 438-51. PMID 17600118 DOI: 10.2353/Ajpath.2007.060977 |
0.526 |
|
| 2007 |
Oudit GY, Kassiri Z, Patel MP, Chappell M, Butany J, Backx PH, Tsushima RG, Scholey JW, Khokha R, Penninger JM. Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice. Cardiovascular Research. 75: 29-39. PMID 17499227 DOI: 10.1016/J.Cardiores.2007.04.007 |
0.59 |
|
| 2006 |
Oudit GY, Herzenberg AM, Kassiri Z, Wong D, Reich H, Khokha R, Crackower MA, Backx PH, Penninger JM, Scholey JW. Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis. The American Journal of Pathology. 168: 1808-20. PMID 16723697 DOI: 10.2353/Ajpath.2006.051091 |
0.547 |
|
| 2006 |
Smookler DS, Mohammed FF, Kassiri Z, Duncan GS, Mak TW, Khokha R. Tissue inhibitor of metalloproteinase 3 regulates TNF-dependent systemic inflammation. Journal of Immunology (Baltimore, Md. : 1950). 176: 721-5. PMID 16393953 DOI: 10.4049/Jimmunol.176.2.721 |
0.301 |
|
| 2006 |
Oudit G, Herzenberg A, Kassiri Z, Wong D, Reich H, Khokha R, Crackower M, Backx P, Penninger J, Scholey J. Angiotensin-Converting Enzyme-2 (ACE2)—A New Player in the Genesis of Glomerular Injury? Journal of the American Society of Nephrology. 17: 2637-2643. DOI: 10.1681/Asn.2006080888 |
0.435 |
|
| 2005 |
Joza N, Oudit GY, Brown D, Bénit P, Kassiri Z, Vahsen N, Benoit L, Patel MM, Nowikovsky K, Vassault A, Backx PH, Wada T, Kroemer G, Rustin P, Penninger JM. Muscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy. Molecular and Cellular Biology. 25: 10261-72. PMID 16287843 DOI: 10.1128/Mcb.25.23.10261-10272.2005 |
0.525 |
|
| 2005 |
Kassiri Z, Oudit GY, Sanchez O, Dawood F, Mohammed FF, Nuttall RK, Edwards DR, Liu PP, Backx PH, Khokha R. Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice. Circulation Research. 97: 380-90. PMID 16037568 DOI: 10.1161/01.Res.0000178789.16929.Cf |
0.576 |
|
| 2005 |
Kassiri Z, Khokha R. Myocardial extra-cellular matrix and its regulation by metalloproteinases and their inhibitors. Thrombosis and Haemostasis. 93: 212-9. PMID 15711735 DOI: 10.1160/Th04-08-0522 |
0.42 |
|
| 2005 |
Ricci R, Eriksson U, Oudit GY, Eferl R, Akhmedov A, Sumara I, Sumara G, Kassiri Z, David JP, Bakiri L, Sasse B, Idarraga MH, Rath M, Kurz D, Theussl HC, et al. Distinct functions of junD in cardiac hypertrophy and heart failure. Genes & Development. 19: 208-13. PMID 15655111 DOI: 10.1101/Gad.327005 |
0.561 |
|
| 2004 |
Fedak PW, Smookler DS, Kassiri Z, Ohno N, Leco KJ, Verma S, Mickle DA, Watson KL, Hojilla CV, Cruz W, Weisel RD, Li RK, Khokha R. TIMP-3 deficiency leads to dilated cardiomyopathy. Circulation. 110: 2401-9. PMID 15262835 DOI: 10.1161/01.Cir.0000134959.83967.2D |
0.419 |
|
| 2002 |
Zobel C, Kassiri Z, Nguyen TT, Meng Y, Backx PH. Prevention of hypertrophy by overexpression of Kv4.2 in cultured neonatal cardiomyocytes. Circulation. 106: 2385-91. PMID 12403671 DOI: 10.1161/01.Cir.0000033970.22130.93 |
0.566 |
|
| 2002 |
Kassiri Z, Hajjar R, Backx PH. Molecular components of transient outward potassium current in cultured neonatal rat ventricular myocytes. Journal of Molecular Medicine (Berlin, Germany). 80: 351-8. PMID 12072910 DOI: 10.1007/S00109-002-0325-7 |
0.521 |
|
| 2002 |
Kassiri Z, Zobel C, Nguyen TT, Molkentin JD, Backx PH. Reduction of I(to) causes hypertrophy in neonatal rat ventricular myocytes. Circulation Research. 90: 578-85. PMID 11909822 DOI: 10.1161/01.Res.0000012223.86441.A1 |
0.559 |
|
| 2001 |
Oudit GY, Kassiri Z, Sah R, Ramirez RJ, Zobel C, Backx PH. The molecular physiology of the cardiac transient outward potassium current (I(to)) in normal and diseased myocardium. Journal of Molecular and Cellular Cardiology. 33: 851-72. PMID 11343410 DOI: 10.1006/Jmcc.2001.1376 |
0.724 |
|
| 2000 |
Kassiri Z, Myers R, Kaprielian R, Banijamali HS, Backx PH. Rate-dependent changes of twitch force duration in rat cardiac trabeculae: a property of the contractile system. The Journal of Physiology. 524: 221-31. PMID 10747194 DOI: 10.1111/J.1469-7793.2000.T01-3-00221.X |
0.702 |
|
| 1999 |
Kaprielian R, Wickenden AD, Kassiri Z, Parker TG, Liu PP, Backx PH. Relationship between K+ channel down-regulation and [Ca2+]i in rat ventricular myocytes following myocardial infarction. The Journal of Physiology. 517: 229-45. PMID 10226162 DOI: 10.1111/J.1469-7793.1999.0229Z.X |
0.726 |
|
| 1998 |
Wickenden AD, Kaprielian R, Kassiri Z, Tsoporis JN, Tsushima R, Fishman GI, Backx PH. The role of action potential prolongation and altered intracellular calcium handling in the pathogenesis of heart failure. Cardiovascular Research. 37: 312-23. PMID 9614488 DOI: 10.1016/S0008-6363(97)00256-3 |
0.724 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2009 |
Oudit GY, Kassiri Z, Jiang C, Liu PP, Poutanen SM, Penninger JM, Butany J. SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS European Journal of Clinical Investigation. 39: 618-625. PMID 19453650 DOI: 10.1111/J.1365-2362.2009.02153.X |
0.298 |
|
| 2005 |
Mohammed FF, Pennington CJ, Kassiri Z, Rubin JS, Soloway PD, Ruther U, Edwards DR, Khokha R. Metalloproteinase inhibitor TIMP-1 affects hepatocyte cell cycle via HGF activation in murine liver regeneration. Hepatology (Baltimore, Md.). 41: 857-67. PMID 15726641 DOI: 10.1002/Hep.20618 |
0.296 |
|
| 2015 |
McLean BA, Zhabyeyev P, Patel VB, Basu R, Parajuli N, DesAulniers J, Murray AG, Kassiri Z, Vanhaesebroeck B, Oudit GY. PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult heart. Cardiovascular Research. 105: 292-303. PMID 25618408 DOI: 10.1093/cvr/cvv016 |
0.294 |
|
| 2004 |
Mohammed FF, Smookler DS, Taylor SE, Fingleton B, Kassiri Z, Sanchez OH, English JL, Matrisian LM, Au B, Yeh WC, Khokha R. Abnormal TNF activity in Timp3-/- mice leads to chronic hepatic inflammation and failure of liver regeneration. Nature Genetics. 36: 969-77. PMID 15322543 DOI: 10.1038/Ng1413 |
0.292 |
|
| 2012 |
Patel VB, Bodiga S, Fan D, Das SK, Wang Z, Wang W, Basu R, Zhong J, Kassiri Z, Oudit GY. Cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensin-converting enzyme 2-null mice. Hypertension. 59: 1195-203. PMID 22508831 DOI: 10.1161/HYPERTENSIONAHA.112.191650 |
0.292 |
|
| 2011 |
Wang W, Bodiga S, Kassiri Z, Penninger J, Oudit G. 491 Loss of Apelin exacerbates post-myocardial infarction remodeling and myocardial ischemia-reperfusion injury Canadian Journal of Cardiology. 27: S240. DOI: 10.1016/J.Cjca.2011.07.411 |
0.289 |
|
| 2016 |
Sakamuri SS, Takawale A, Basu R, Fedak PW, Freed D, Sergi C, Oudit GY, Kassiri Z. Differential impact of mechanical unloading on structural and nonstructural components of the extracellular matrix in advanced human heart failure. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 26963743 DOI: 10.1016/J.Trsl.2016.02.006 |
0.289 |
|
| 2015 |
Takawale A, Sakamuri SS, Kassiri Z. Extracellular matrix communication and turnover in cardiac physiology and pathology. Comprehensive Physiology. 5: 687-719. PMID 25880510 DOI: 10.1002/cphy.c140045 |
0.286 |
|
| 2011 |
Bodiga S, Zhong JC, Wang W, Basu R, Lo J, Liu GC, Guo D, Holland SM, Scholey JW, Penninger JM, Kassiri Z, Oudit GY. Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit. Cardiovascular Research. 91: 151-61. PMID 21285291 DOI: 10.1093/Cvr/Cvr036 |
0.285 |
|
| 2013 |
Patel V, Basu R, Lee J, Morton J, Parajuli N, Davidge S, Kassiri Z, Oudit G. Angiotensin Converting Enzyme 2 Deficiency Exacerbates Angiotensin II Induced Loss of Smooth Muscle Cells Leading to Enhanced Adverse Vascular Remodeling Canadian Journal of Cardiology. 29: S179-S180. DOI: 10.1016/J.Cjca.2013.07.282 |
0.285 |
|
| 2022 |
Sosnowski DK, Jamieson KL, Gruzdev A, Li Y, Valencia R, Yousef A, Kassiri Z, Zeldin DC, Seubert JM. Cardiomyocyte-specific disruption of soluble epoxide hydrolase limits inflammation to preserve cardiac function. American Journal of Physiology. Heart and Circulatory Physiology. PMID 35985007 DOI: 10.1152/ajpheart.00217.2022 |
0.284 |
|
| 2012 |
Mori J, Basu R, McLean BA, Das SK, Zhang L, Patel VB, Wagg CS, Kassiri Z, Lopaschuk GD, Oudit GY. Agonist-induced hypertrophy and diastolic dysfunction are associated with selective reduction in glucose oxidation: a metabolic contribution to heart failure with normal ejection fraction. Circulation. Heart Failure. 5: 493-503. PMID 22705769 DOI: 10.1161/CIRCHEARTFAILURE.112.966705 |
0.283 |
|
| 2011 |
Kandalam V, Basu R, Moore L, Fan D, Wang X, Jaworski DM, Oudit GY, Kassiri Z. Lack of tissue inhibitor of metalloproteinases 2 leads to exacerbated left ventricular dysfunction and adverse extracellular matrix remodeling in response to biomechanical stress. Circulation. 124: 2094-105. PMID 21986284 DOI: 10.1161/CIRCULATIONAHA.111.030338 |
0.281 |
|
| 2010 |
Ali MA, Cho WJ, Hudson B, Kassiri Z, Granzier H, Schulz R. Titin is a target of matrix metalloproteinase-2: implications in myocardial ischemia/reperfusion injury. Circulation. 122: 2039-47. PMID 21041693 DOI: 10.1161/Circulationaha.109.930222 |
0.281 |
|
| 2007 |
Sun M, Chen M, Dawood F, Zurawska U, Li JY, Parker T, Kassiri Z, Kirshenbaum LA, Arnold M, Khokha R, Liu PP. Tumor necrosis factor-alpha mediates cardiac remodeling and ventricular dysfunction after pressure overload state. Circulation. 115: 1398-407. PMID 17353445 DOI: 10.1161/Circulationaha.106.643585 |
0.28 |
|
| 2015 |
Wang X, Berry E, Hernandez-Anzaldo S, Takawale A, Kassiri Z, Fernandez-Patron C. Matrix metalloproteinase-2 mediates a mechanism of metabolic cardioprotection consisting of negative regulation of the sterol regulatory element-binding protein-2/3-hydroxy-3-methylglutaryl-CoA reductase pathway in the heart. Hypertension. 65: 882-8. PMID 25646300 DOI: 10.1161/Hypertensionaha.114.04989 |
0.275 |
|
| 2018 |
Lindsey ML, Kassiri Z, Virag JAI, de Castro Bras LE, Scherrer-Crosbie M. Guidelines for Measuring Cardiac Physiology in Mice. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29351456 DOI: 10.1152/ajpheart.00339.2017 |
0.274 |
|
| 2013 |
McLean B, DesAulniers J, Zhabyeyev P, Kassiri Z, Oudit G. PI3Kα Is Required for Recovery From Transient CRE/Tamoxifen Cardiotoxicity, but Is not Required for Normal Cardiac Function in the Adult Mouse Heart Canadian Journal of Cardiology. 29: S247-S248. DOI: 10.1016/j.cjca.2013.07.401 |
0.272 |
|
| 2017 |
Takawale A, Zhang P, Patel VB, Wang X, Oudit G, Kassiri Z. Tissue Inhibitor of Matrix Metalloproteinase-1 Promotes Myocardial Fibrosis by Mediating CD63-Integrin β1 Interaction. Hypertension (Dallas, Tex. : 1979). PMID 28373589 DOI: 10.1161/HYPERTENSIONAHA.117.09045 |
0.271 |
|
| 2012 |
Moore L, Fan D, Basu R, Kandalam V, Kassiri Z. Tissue inhibitor of metalloproteinases (TIMPs) in heart failure. Heart Failure Reviews. 17: 693-706. PMID 21717224 DOI: 10.1007/s10741-011-9266-y |
0.266 |
|
| 2013 |
Patel VB, Wang Z, Fan D, Zhabyeyev P, Basu R, Das SK, Wang W, Desaulniers J, Holland SM, Kassiri Z, Oudit GY. Loss of p47phox subunit enhances susceptibility to biomechanical stress and heart failure because of dysregulation of cortactin and actin filaments. Circulation Research. 112: 1542-56. PMID 23553616 DOI: 10.1161/CIRCRESAHA.111.300299 |
0.265 |
|
| 2011 |
Basu R, Morton J, Kandalam V, Wang X, Davidge S, Oudit G, Kassiri Z. 148 Loss of TIMP3 leads to adverse remodeling of the vascular wall structure and development of Abdominal Aortic Aneurysm following angiotensin II treatment Canadian Journal of Cardiology. 27: S115-S116. DOI: 10.1016/J.Cjca.2011.07.105 |
0.261 |
|
| 2016 |
Fan D, Takawale A, Shen M, Samokhvalov V, Basu R, Patel V, Wang X, Fernandez-Patron C, Seubert JM, Oudit GY, Kassiri Z. A Disintegrin and Metalloprotease-17 Regulates Pressure Overload-Induced Myocardial Hypertrophy and Dysfunction Through Proteolytic Processing of Integrin β1. Hypertension (Dallas, Tex. : 1979). PMID 27550917 DOI: 10.1161/Hypertensionaha.116.07566 |
0.259 |
|
| 2006 |
English JL, Kassiri Z, Koskivirta I, Atkinson SJ, Di Grappa M, Soloway PD, Nagase H, Vuorio E, Murphy G, Khokha R. Individual Timp deficiencies differentially impact pro-MMP-2 activation. The Journal of Biological Chemistry. 281: 10337-46. PMID 16469749 DOI: 10.1074/Jbc.M512009200 |
0.257 |
|
| 2017 |
Takawale A, Zhang P, Azad A, Wang W, Wang X, Murray AG, Kassiri Z. Myocardial overexpression of TIMP3 following myocardial infarction exerts beneficial effects through promoting angiogenesis and suppressing early proteolysis. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00108.2017. PMID 28550172 DOI: 10.1152/ajpheart.00108.2017 |
0.257 |
|
| 2009 |
Kassiri Z, Zhong J, Guo D, Basu R, Wang X, Liu PP, Scholey JW, Penninger JM, Oudit GY. Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction. Circulation. Heart Failure. 2: 446-55. PMID 19808375 DOI: 10.1161/Circheartfailure.108.840124 |
0.256 |
|
| 2010 |
Kandalam V, Basu R, Abraham T, Wang X, Soloway PD, Jaworski DM, Oudit GY, Kassiri Z. TIMP2 deficiency accelerates adverse post-myocardial infarction remodeling because of enhanced MT1-MMP activity despite lack of MMP2 activation. Circulation Research. 106: 796-808. PMID 20056917 DOI: 10.1161/CIRCRESAHA.109.209189 |
0.254 |
|
| 2013 |
Wang W, McKinnie SM, Patel VB, Haddad G, Wang Z, Zhabyeyev P, Das SK, Basu R, McLean B, Kandalam V, Penninger JM, Kassiri Z, Vederas JC, Murray AG, Oudit GY. Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues. Journal of the American Heart Association. 2: e000249. PMID 23817469 DOI: 10.1161/Jaha.113.000249 |
0.253 |
|
| 2021 |
Jamieson KL, Darwesh AM, Sosnowski DK, Zhang H, Shah S, Zhabyeyev P, Yang J, Hammock BD, Edin ML, Zeldin DC, Oudit GY, Kassiri Z, Seubert JM. Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury. International Journal of Molecular Sciences. 22. PMID 33567578 DOI: 10.3390/ijms22041691 |
0.252 |
|
| 2015 |
Hernandez-Anzaldo S, Berry E, Brglez V, Leung D, Yun TJ, Lee JS, Filep JG, Kassiri Z, Cheong C, Lambeau G, Lehner R, Fernandez-Patron C. Identification of a Novel Heart-Liver Axis: Matrix Metalloproteinase-2 Negatively Regulates Cardiac Secreted Phospholipase A2 to Modulate Lipid Metabolism and Inflammation in the Liver. Journal of the American Heart Association. 4. PMID 26567374 DOI: 10.1161/JAHA.115.002553 |
0.249 |
|
| 2022 |
Al Rimon R, Nelson VL, Brunt KR, Kassiri Z. High Impact Opportunities to Address Ischemia: A Focus on Heart and Circulatory Research. American Journal of Physiology. Heart and Circulatory Physiology. PMID 36331554 DOI: 10.1152/ajpheart.00402.2022 |
0.248 |
|
| 2021 |
Chen X, Zhabyeyev P, Azad AK, Vanhaesebroeck B, Grueter CE, Murray AG, Kassiri Z, Oudit GY. Pharmacological and cell-specific genetic PI3Kα inhibition worsens cardiac remodeling after myocardial infarction. Journal of Molecular and Cellular Cardiology. 157: 17-30. PMID 33887328 DOI: 10.1016/j.yjmcc.2021.04.004 |
0.247 |
|
| 2009 |
ZHONG J, OUDIT G, ZHU D, KASSIRI Z, GAO P, PENNINGER J. Prevention of angiotensin II-induced hypertension and cardiac remodeling by recombinant human angiotensin-converting enzyme 2 in mice International Journal of Cardiology. 137: S131. DOI: 10.1016/J.Ijcard.2009.09.446 |
0.246 |
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| 2014 |
Putko BN, Wang Z, Lo J, Anderson T, Becher H, Dyck JR, Kassiri Z, Oudit GY. Circulating levels of tumor necrosis factor-alpha receptor 2 are increased in heart failure with preserved ejection fraction relative to heart failure with reduced ejection fraction: evidence for a divergence in pathophysiology. Plos One. 9: e99495. PMID 24923671 DOI: 10.1371/journal.pone.0099495 |
0.245 |
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| 2024 |
Lindsey ML, Brunt KR, Kleinbongard P, Carter JR, Ripplinger CM, Kassiri Z, Hansell Keehan K, LeBlanc AJ, Kirk JA. The heart of physiological reports. Physiological Reports. 12: e15962. PMID 38439748 DOI: 10.14814/phy2.15962 |
0.237 |
|
| 2011 |
Odenbach J, Wang X, Cooper S, Chow FL, Oka T, Lopaschuk G, Kassiri Z, Fernandez-Patron C. MMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE. Hypertension. 57: 123-30. PMID 21079048 DOI: 10.1161/Hypertensionaha.110.159525 |
0.237 |
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| 2018 |
Jana S, Zhang H, Lopaschuk GD, Freed DH, Sergi C, Kantor PF, Oudit GY, Kassiri Z. Disparate Remodeling of the Extracellular Matrix and Proteoglycans in Failing Pediatric Versus Adult Hearts. Journal of the American Heart Association. 7: e010427. PMID 30371322 DOI: 10.1161/Jaha.118.010427 |
0.235 |
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| 2014 |
Patel VB, Clarke N, Wang Z, Fan D, Parajuli N, Basu R, Putko B, Kassiri Z, Turner AJ, Oudit GY. Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: a positive feedback mechanism in the RAS. Journal of Molecular and Cellular Cardiology. 66: 167-76. PMID 24332999 DOI: 10.1016/j.yjmcc.2013.11.017 |
0.234 |
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| 2021 |
Lindsey ML, Brunt KR, Kirk JA, Kleinbongard P, Calvert JW, de Castro Brás LE, DeLeon-Pennell KY, Del Re DP, Frangogiannis NG, Frantz S, Gumina RJ, Halade G, Jones SP, Ritchie RH, Spinale FG, ... ... Kassiri Z, et al. Guidelines for in vivo mouse models of myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34623181 DOI: 10.1152/ajpheart.00459.2021 |
0.234 |
|
| 2020 |
Aujla PK, Kassiri Z. Diverse origins and activation of fibroblasts in cardiac fibrosis. Cellular Signalling. 109869. PMID 33278559 DOI: 10.1016/j.cellsig.2020.109869 |
0.233 |
|
| 2014 |
Ezekowitz JA, Becher H, Belenkie I, Clark AM, Duff HJ, Friedrich MG, Haykowsky MJ, Howlett JG, Kassiri Z, Kaul P, Kim DH, Knudtson ML, Light PE, Lopaschuk GD, McAlister FA, et al. The Alberta Heart Failure Etiology and Analysis Research Team (HEART) study. Bmc Cardiovascular Disorders. 14: 91. PMID 25063541 DOI: 10.1186/1471-2261-14-91 |
0.233 |
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| 2013 |
Song B, Zhang ZZ, Zhong JC, Yu XY, Oudit GY, Jin HY, Lu L, Xu YL, Kassiri Z, Shen WF, Gao PJ, Zhu DL. Loss of angiotensin-converting enzyme 2 exacerbates myocardial injury via activation of the CTGF-fractalkine signaling pathway. Circulation Journal : Official Journal of the Japanese Circulation Society. 77: 2997-3006. PMID 24161906 DOI: 10.1253/circj.CJ-13-0805 |
0.232 |
|
| 2022 |
Viveiros A, Noyce RS, Gheblawi M, Colombo D, Bilawchuk LM, Clemente-Casares X, Marchant DJ, Kassiri Z, Del Nonno F, Evans DH, Oudit GY. SARS-CoV-2 Infection Downregulates Myocardial ACE2 and Potentiates Cardiac Inflammation in Humans and Hamsters. American Journal of Physiology. Heart and Circulatory Physiology. PMID 36367689 DOI: 10.1152/ajpheart.00578.2022 |
0.231 |
|
| 2010 |
Awad AE, Kandalam V, Chakrabarti S, Wang X, Penninger JM, Davidge ST, Oudit GY, Kassiri Z. Tumor necrosis factor induces matrix metalloproteinases in cardiomyocytes and cardiofibroblasts differentially via superoxide production in a PI3Kgamma-dependent manner. American Journal of Physiology. Cell Physiology. 298: C679-92. PMID 20007453 DOI: 10.1152/Ajpcell.00351.2009 |
0.231 |
|
| 2012 |
Patel VB, Bodiga S, Basu R, Das SK, Wang W, Wang Z, Lo J, Grant MB, Zhong J, Kassiri Z, Oudit GY. Loss of angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: a critical role of the angiotensin II/AT1 receptor axis. Circulation Research. 110: 1322-35. PMID 22474255 DOI: 10.1161/Circresaha.112.268029 |
0.228 |
|
| 2010 |
Oudit GY, Zhong J, Basu R, Guo D, Penninger JM, Kassiri Z. Angiotensin Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis and Diastolic Dysfunction Journal of Cardiac Failure. 16: S16. DOI: 10.1016/J.Cardfail.2010.06.054 |
0.226 |
|
| 2020 |
Zhang H, Viveiros A, Nikhanj A, Nguyen Q, Wang K, Wang W, Freed DH, Mullen JC, MacArthur R, Kim DH, Tymchak W, Sergi CM, Kassiri Z, Wang S, Oudit GY. The Human Explanted Heart Program: A translational bridge for cardiovascular medicine. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1867: 165995. PMID 33141063 DOI: 10.1016/j.bbadis.2020.165995 |
0.226 |
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| 2019 |
Chute M, Aujla P, Jana S, Kassiri Z. The Non-Fibrillar Side of Fibrosis: Contribution of the Basement Membrane, Proteoglycans, and Glycoproteins to Myocardial Fibrosis. Journal of Cardiovascular Development and Disease. 6. PMID 31547598 DOI: 10.3390/jcdd6040035 |
0.224 |
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| 2016 |
Spinale FG, Frangogiannis NG, Hinz B, Holmes JW, Kassiri Z, Lindsey ML. Crossing Into the Next Frontier of Cardiac Extracellular Matrix Research. Circulation Research. 119: 1040-1045. PMID 27789578 DOI: 10.1161/Circresaha.116.309916 |
0.221 |
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| 2010 |
Zhong J, Basu R, Guo D, Chow FL, Byrns S, Schuster M, Loibner H, Wang XH, Penninger JM, Kassiri Z, Oudit GY. Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction. Circulation. 122: 717-28, 18 p followi. PMID 20679547 DOI: 10.1161/Circulationaha.110.955369 |
0.218 |
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| 2014 |
Fernandez-Patron C, Wang X, Kassiri Z, Hernandez-Anzaldo S, Berry E, Zhang D, Li L. MMP-2 MEDIATES A MECHANISM OF METABOLIC CARDIOPROTECTION CONSISTING OF NEGATIVE REGULATION OF THE SREBP/HMGCR/ADAM-12 PATHWAY IN THE HEART Canadian Journal of Cardiology. 30: S211. DOI: 10.1016/j.cjca.2014.07.349 |
0.217 |
|
| 2012 |
Zhong J, Song B, Jin H, Xu Y, Kassiri Z, Zhang Z, Gao P, Penninger JM, Oudit GY, Zhong J. ANGIOTENSIN II-MEDIATED MYOCARDIAL EXPRESSION OF MMP2, MMP9 AND MT1-MMP WERE ENHANCED IN ACE2-NULL MICE Heart. 98: E9.2-E9. DOI: 10.1136/Heartjnl-2012-302920A.19 |
0.216 |
|
| 2017 |
Jamieson KL, Samokhvalov V, Akhnokh M, Lee K, Cho WJ, Takawale A, Wang X, Kassiri Z, Seubert JM. Genetic Deletion of Soluble Epoxide Hydrolase Provides Cardioprotective Responses Following Myocardial Infarction in Aged Mice. Prostaglandins & Other Lipid Mediators. PMID 28104457 DOI: 10.1016/j.prostaglandins.2017.01.001 |
0.215 |
|
| 2016 |
Fernandez-Patron C, Kassiri Z, Leung D. Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients. Comprehensive Physiology. 6: 1935-1949. PMID 27783864 DOI: 10.1002/cphy.c160010 |
0.215 |
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| 2015 |
Patel VB, Takawale A, Ramprasath T, Das SK, Basu R, Grant MB, Hall DA, Kassiri Z, Oudit GY. Antagonism of angiotensin 1-7 prevents the therapeutic effects of recombinant human ACE2. Journal of Molecular Medicine (Berlin, Germany). PMID 25874965 DOI: 10.1007/S00109-015-1285-Z |
0.214 |
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| 2009 |
Wang X, Chow FL, Oka T, Hao L, Lopez-Campistrous A, Kelly S, Cooper S, Odenbach J, Finegan BA, Schulz R, Kassiri Z, Lopaschuk GD, Fernandez-Patron C. Matrix metalloproteinase-7 and ADAM-12 (a disintegrin and metalloproteinase-12) define a signaling axis in agonist-induced hypertension and cardiac hypertrophy. Circulation. 119: 2480-9. PMID 19398663 DOI: 10.1161/Circulationaha.108.835488 |
0.212 |
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| 2012 |
Jin HY, Song B, Oudit GY, Davidge ST, Yu HM, Jiang YY, Gao PJ, Zhu DL, Ning G, Kassiri Z, Penninger JM, Zhong JC. ACE2 deficiency enhances angiotensin II-mediated aortic profilin-1 expression, inflammation and peroxynitrite production. Plos One. 7: e38502. PMID 22693641 DOI: 10.1371/Journal.Pone.0038502 |
0.209 |
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| 2013 |
Zhabyeyev P, Gandhi M, Mori J, Basu R, Kassiri Z, Clanachan A, Lopaschuk GD, Oudit GY. Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. Cardiovascular Research. 97: 676-85. PMID 23257023 DOI: 10.1093/cvr/cvs424 |
0.204 |
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| 2021 |
Lindsey ML, de Castro Bras LE, DeLeon-Pennell KY, Frangogiannis NG, Halade GV, O'Meara CC, Spinale FG, Kassiri Z, Kirk JA, Kleinbongard P, Ripplinger CM, Brunt KR. Reperfused vs. Non-reperfused Myocardial Infarction: When to Use Which Model. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34114891 DOI: 10.1152/ajpheart.00234.2021 |
0.204 |
|
| 2011 |
Zhong J, Guo D, Chen CB, Wang W, Schuster M, Loibner H, Penninger JM, Scholey JW, Kassiri Z, Oudit GY. Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2. Hypertension. 57: 314-22. PMID 21189404 DOI: 10.1161/Hypertensionaha.110.164244 |
0.195 |
|
| 2011 |
Zhong JC, Jin HY, Shen WL, Niu WQ, Li Y, Gao PJ, Zhu DL, Kassiri Z, Oudit GY. PREVENTION OF PRESSURE OVERLOAD-INDUCED MYOCARDIAL FIBROSIS AND PATHOLOGICAL REMODELING BY ANGIOTENSIN CONVERTING ENZYME 2 Journal of Hypertension. 29: e58. DOI: 10.1097/00004872-201106001-00147 |
0.192 |
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| 2015 |
Zhang P, Shen M, Fernandez-Patron C, Kassiri Z. ADAMs family and relatives in cardiovascular physiology and pathology. Journal of Molecular and Cellular Cardiology. PMID 26522853 DOI: 10.1016/J.Yjmcc.2015.10.031 |
0.192 |
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| 2018 |
Chute M, Jana S, Kassiri Z. Disintegrin and metalloproteinases (ADAMs and ADAM-TSs), the emerging family of proteases in heart physiology and pathology Current Opinion in Physiology. 1: 34-45. DOI: 10.1016/J.COPHYS.2017.07.002 |
0.192 |
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| 2014 |
Takawale A, Fan D, Basu R, Shen M, Parajuli N, Wang W, Wang X, Oudit GY, Kassiri Z. Myocardial recovery from ischemia-reperfusion is compromised in the absence of tissue inhibitor of metalloproteinase 4. Circulation. Heart Failure. 7: 652-62. PMID 24842912 DOI: 10.1161/CIRCHEARTFAILURE.114.001113 |
0.191 |
|
| 2015 |
Fan D, Takawale A, Shen M, Wang W, Wang X, Basu R, Oudit GY, Kassiri Z. Cardiomyocyte ADAM17 Is Essential in Post-Myocardial Infarction Repair by Regulating Angiogenesis. Circulation. Heart Failure. PMID 26136458 DOI: 10.1161/CIRCHEARTFAILURE.114.002029 |
0.191 |
|
| 2009 |
Kassiri Z, Oudit GY, Kandalam V, Awad A, Wang X, Ziou X, Maeda N, Herzenberg AM, Scholey JW. Loss of TIMP3 enhances interstitial nephritis and fibrosis. Journal of the American Society of Nephrology : Jasn. 20: 1223-35. PMID 19406980 DOI: 10.1681/Asn.2008050492 |
0.19 |
|
| 2012 |
Basu R, Fan D, Kandalam V, Lee J, Das SK, Wang X, Baldwin TA, Oudit GY, Kassiri Z. Loss of Timp3 gene leads to abdominal aortic aneurysm formation in response to angiotensin II. The Journal of Biological Chemistry. 287: 44083-96. PMID 23144462 DOI: 10.1074/Jbc.M112.425652 |
0.185 |
|
| 2010 |
Guo D, Basu R, Chow FL, Wang X, Kassiri Z, Oudit GY. Dual Loss of PI3Kα and PI3Kγ Leads to a Paradoxical Increase in AKT Activation and Physiological Hypertrophy Journal of Cardiac Failure. 16: S35. DOI: 10.1016/j.cardfail.2010.06.121 |
0.184 |
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| 2019 |
Wang W, Shen M, Fischer C, Basu R, Hazra S, Couvineau P, Paul M, Wang F, Toth S, Mix DS, Poglitsch M, Gerard NP, Bouvier M, Vederas JC, Penninger JM, ... Kassiri Z, et al. Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs. Proceedings of the National Academy of Sciences of the United States of America. PMID 31189595 DOI: 10.1073/Pnas.1900152116 |
0.18 |
|
| 2014 |
Wang Z, Famulski K, Lee J, Das SK, Wang X, Halloran P, Oudit GY, Kassiri Z. TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury. Kidney International. 85: 82-93. PMID 23760282 DOI: 10.1038/Ki.2013.225 |
0.179 |
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| 2012 |
Basu R, Lee J, Wang Z, Patel VB, Fan D, Das SK, Liu GC, John R, Scholey JW, Oudit GY, Kassiri Z. Loss of TIMP3 selectively exacerbates diabetic nephropathy. American Journal of Physiology. Renal Physiology. 303: F1341-52. PMID 22896043 DOI: 10.1152/ajprenal.00349.2012 |
0.177 |
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| 2020 |
Fan D, Kassiri Z. Biology of Tissue Inhibitor of Metalloproteinase 3 (TIMP3), and Its Therapeutic Implications in Cardiovascular Pathology. Frontiers in Physiology. 11: 661. PMID 32612540 DOI: 10.3389/fphys.2020.00661 |
0.176 |
|
| 2015 |
Das SK, Wang W, Zhabyeyev P, Basu R, McLean B, Fan D, Parajuli N, DesAulniers J, Patel VB, Hajjar RJ, Dyck JR, Kassiri Z, Oudit GY. Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy. Scientific Reports. 5: 18132. PMID 26638758 DOI: 10.1038/srep18132 |
0.174 |
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| 2014 |
Haddad G, Zhabyeyev P, Farhan M, Zhu LF, Kassiri Z, Rayner DC, Vanhaesebroeck B, Oudit GY, Murray AG. Phosphoinositide 3-kinase β mediates microvascular endothelial repair of thrombotic microangiopathy. Blood. 124: 2142-9. PMID 25139353 DOI: 10.1182/blood-2014-02-557975 |
0.173 |
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| 2015 |
Berry E, Hernandez-Anzaldo S, Ghomashchi F, Lehner R, Murakami M, Gelb MH, Kassiri Z, Wang X, Fernandez-Patron C. Matrix metalloproteinase-2 negatively regulates cardiac secreted phospholipase A2 to modulate inflammation and fever. Journal of the American Heart Association. 4. PMID 25820137 DOI: 10.1161/Jaha.115.001868 |
0.171 |
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| 2018 |
Zhabyeyev P, Das SK, Basu R, Shen M, Patel VB, Kassiri Z, Oudit GY. TIMP3 deficiency exacerbates iron-overload mediated cardiomyopathy and liver disease. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29373036 DOI: 10.1152/ajpheart.00597.2017 |
0.169 |
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| 2021 |
Wang K, Gheblawi M, Nikhanj A, Munan M, MacIntyre E, O'Neil C, Poglitsch M, Colombo D, Del Nonno F, Kassiri Z, Sligl W, Oudit GY. Dysregulation of ACE (Angiotensin-Converting Enzyme)-2 and Renin-Angiotensin Peptides in SARS-CoV-2 Mediated Mortality and End-Organ Injuries. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA12118. PMID 34844421 DOI: 10.1161/HYPERTENSIONAHA.121.18295 |
0.169 |
|
| 2012 |
Zhong J, Jin H, Song B, Kassiri Z, Zhang Z, Gao P, Zhu D, Penninger JM, Oudit GY. 1040 ANGIOTENSIN II-MEDIATED VASCULAR INFLAMMATION IS ACCELERATED IN ACE2 NULL MICE WITH ENHANCED PROFILIN-1 EXPRESSION Journal of Hypertension. 30: e303. DOI: 10.1097/01.Hjh.0000420984.25019.C2 |
0.168 |
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| 2014 |
Patel VB, Zhong JC, Fan D, Basu R, Morton JS, Parajuli N, McMurtry MS, Davidge ST, Kassiri Z, Oudit GY. Angiotensin-converting enzyme 2 is a critical determinant of angiotensin II-induced loss of vascular smooth muscle cells and adverse vascular remodeling. Hypertension. 64: 157-64. PMID 24799609 DOI: 10.1161/HYPERTENSIONAHA.114.03388 |
0.166 |
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| 2010 |
Zhong J, Chow FL, Wang X, Kassiri Z, Oudit GY. Loss of ACE2 Accelerates Pressure Overload-Induced Myocardial Oxidative Stress and Ventricular Dysfunction Journal of Cardiac Failure. 16: S11. DOI: 10.1016/j.cardfail.2010.06.036 |
0.163 |
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| 2016 |
Shen M, Morton J, Davidge ST, Kassiri Z. Loss of smooth muscle cell disintegrin and metalloproteinase 17 transiently suppresses angiotensin II-induced hypertension and end-organ damage. Journal of Molecular and Cellular Cardiology. PMID 27993561 DOI: 10.1016/j.yjmcc.2016.12.001 |
0.162 |
|
| 2018 |
Jana S, Zhang H, Freed D, Lopaschuk G, Kantor P, Oudit G, Kassiri Z. Remodeling of myocardial extracellular matrix and proteoglycans varies in pediatric versus adult patients with dilated cardiomyopathy Journal of Molecular and Cellular Cardiology. 124: 115. DOI: 10.1016/J.Yjmcc.2018.07.096 |
0.159 |
|
| 2016 |
Akhnokh MK, Yang FH, Samokhvalov V, Jamieson KL, Cho WJ, Wagg C, Takawale A, Wang X, Lopaschuk GD, Hammock BD, Kassiri Z, Seubert JM. Inhibition of Soluble Epoxide Hydrolase Limits Mitochondrial Damage and Preserves Function Following Ischemic Injury. Frontiers in Pharmacology. 7: 133. PMID 27375480 DOI: 10.3389/Fphar.2016.00133 |
0.157 |
|
| 2023 |
Masoud AG, Lin J, Zhu LF, Tao K, Ness NW, Kassiri Z, Moore RB, Vanhaesebroeck B, West L, Anderson CC, Oudit GY, Murray AG. Endothelial phosphoinositide 3-kinase-β inactivation confers protection from immune-mediated vascular injury. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 23: 202-213. PMID 36804130 DOI: 10.1016/j.ajt.2022.11.014 |
0.156 |
|
| 2013 |
Basu R, Lee J, Morton JS, Takawale A, Fan D, Kandalam V, Wang X, Davidge ST, Kassiri Z. TIMP3 is the primary TIMP to regulate agonist-induced vascular remodelling and hypertension. Cardiovascular Research. 98: 360-71. PMID 23524300 DOI: 10.1093/cvr/cvt067 |
0.156 |
|
| 2020 |
Jana S, Chute M, Hu M, Winkelaar G, Owen CA, Oudit GY, Kassiri Z. ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)-Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314600. PMID 32522006 DOI: 10.1161/ATVBAHA.120.314600 |
0.155 |
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| 2019 |
Masoud AG, Lin J, Azad AK, Farhan MA, Fischer C, Zhu LF, Zhang H, Sis B, Kassiri Z, Moore RB, Kim D, Anderson CC, Vederas JC, Adam BA, Oudit GY, et al. Apelin directs endothelial cell differentiation and vascular repair following immune-mediated injury. The Journal of Clinical Investigation. PMID 31738185 DOI: 10.1172/Jci128469 |
0.153 |
|
| 2010 |
Guo D, Kassiri Z, Penninger JM, Oudit GY. Loss of PI3Kγ Enhances cAMP-Dependent MMP Remodeling of N-Cadherin Adhesion Complexes and Extracellular Matrix in Response to Biomechanical Stress Journal of Cardiac Failure. 16: S9. DOI: 10.1016/J.Cardfail.2010.06.031 |
0.151 |
|
| 2012 |
Rueda-Clausen CF, Morton JS, Oudit GY, Kassiri Z, Jiang Y, Davidge ST. Effects of hypoxia-induced intrauterine growth restriction on cardiac siderosis and oxidative stress. Journal of Developmental Origins of Health and Disease. 3: 350-7. PMID 25102264 DOI: 10.1017/S2040174412000219 |
0.15 |
|
| 2018 |
Shen M, Hu M, Fedak PW, Oudit GY, Kassiri Z. Cell-Specific Functions of ADAM17 Regulate the Progression of Thoracic Aortic Aneurysm. Circulation Research. PMID 29930147 DOI: 10.1161/CIRCRESAHA.118.313181 |
0.15 |
|
| 2012 |
Rey-Parra GJ, Vadivel A, Coltan L, Hall A, Eaton F, Schuster M, Loibner H, Penninger JM, Kassiri Z, Oudit GY, Thébaud B. Angiotensin converting enzyme 2 abrogates bleomycin-induced lung injury Journal of Molecular Medicine. 90: 637-647. PMID 22246130 DOI: 10.1007/S00109-012-0859-2 |
0.149 |
|
| 2005 |
Reich H, Tritchler D, Herzenberg AM, Kassiri Z, Zhou X, Gao W, Scholey JW. Albumin activates ERK via EGF receptor in human renal epithelial cells. Journal of the American Society of Nephrology : Jasn. 16: 1266-78. PMID 15829704 DOI: 10.1681/ASN.2004030222 |
0.148 |
|
| 2017 |
Sakamuri SSVP, Watts R, Takawale A, Wang X, Hernandez-Anzaldo S, Bahitham W, Fernandez-Patron C, Lehner R, Kassiri Z. Absence of Tissue Inhibitor of Metalloproteinase-4 (TIMP4) ameliorates high fat diet-induced obesity in mice due to defective lipid absorption. Scientific Reports. 7: 6210. PMID 28740132 DOI: 10.1038/s41598-017-05951-4 |
0.148 |
|
| 2021 |
Hu M, Jana S, Kilic T, Wang F, Shen M, Winkelaar G, Oudit GY, Rayner K, Zhang DW, Kassiri Z. Loss of TIMP4 (Tissue Inhibitor of Metalloproteinase 4) Promotes Atherosclerotic Plaque Deposition in the Abdominal Aorta Despite Suppressed Plasma Cholesterol Levels. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120315522. PMID 33792349 DOI: 10.1161/ATVBAHA.120.315522 |
0.144 |
|
| 2017 |
Das SK, Patel VB, Basu R, Wang W, DesAulniers J, Kassiri Z, Oudit GY. Females Are Protected From Iron-Overload Cardiomyopathy Independent of Iron Metabolism: Key Role of Oxidative Stress. Journal of the American Heart Association. 6. PMID 28115312 DOI: 10.1161/JAHA.116.003456 |
0.144 |
|
| 2017 |
Das SK, Zhabyeyev P, Basu R, Patel VB, Dyck JRB, Kassiri Z, Oudit GY. Advanced iron-overload cardiomyopathy in a genetic murine model is rescued by resveratrol therapy. Bioscience Reports. PMID 29208771 DOI: 10.1042/BSR20171302 |
0.143 |
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| 2014 |
Mori J, Patel VB, Abo Alrob O, Basu R, Altamimi T, Desaulniers J, Wagg CS, Kassiri Z, Lopaschuk GD, Oudit GY. Angiotensin 1-7 ameliorates diabetic cardiomyopathy and diastolic dysfunction in db/db mice by reducing lipotoxicity and inflammation. Circulation. Heart Failure. 7: 327-39. PMID 24389129 DOI: 10.1161/CIRCHEARTFAILURE.113.000672 |
0.143 |
|
| 2014 |
Fan D, Creemers EE, Kassiri Z. Matrix as an interstitial transport system. Circulation Research. 114: 889-902. PMID 24577968 DOI: 10.1161/CIRCRESAHA.114.302335 |
0.131 |
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| 2022 |
Hu M, Hiroyasu S, Granville DJ, Kassiri Z. Implications of SM22α-Cre expression in keratinocytes and un-anticipated inflammatory skin lesions in a model of atherosclerosis. American Journal of Physiology. Heart and Circulatory Physiology. PMID 35930445 DOI: 10.1152/ajpheart.00325.2022 |
0.131 |
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| 2024 |
Lindsey ML, Kirk JA, LeBlanc AJ, Brunt KR, Carter JR, Hansell Keehan K, Ripplinger CM, Kleinbongard P, Kassiri Z. Looking Backward to Plan for Forward. American Journal of Physiology. Heart and Circulatory Physiology. PMID 38551484 DOI: 10.1152/ajpheart.00154.2024 |
0.12 |
|
| 2021 |
Viveiros A, Gheblawi M, Aujla PK, Sosnowski DK, Seubert JM, Kassiri Z, Oudit GY. Sex- and age-specific regulation of ACE2: Insights into severe COVID-19 susceptibility. Journal of Molecular and Cellular Cardiology. 164: 13-16. PMID 34774871 DOI: 10.1016/j.yjmcc.2021.11.003 |
0.117 |
|
| 2007 |
Hojilla CV, Kim I, Kassiri Z, Fata JE, Fang H, Khokha R. Metalloproteinase axes increase beta-catenin signaling in primary mouse mammary epithelial cells lacking TIMP3. Journal of Cell Science. 120: 1050-60. PMID 17327279 DOI: 10.1242/Jcs.003335 |
0.115 |
|
| 2011 |
Luong C, Rey-Perra J, Vadivel A, Gilmour G, Sauve Y, Koonen D, Walker D, Todd KG, Gressens P, Kassiri Z, Nadeem K, Morgan B, Eaton F, Dyck JR, Archer SL, et al. Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia. Circulation. 123: 2120-31. PMID 21537000 DOI: 10.1161/Circulationaha.108.845909 |
0.114 |
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| 2016 |
van der Veen JN, Lingrell S, Gao X, Quiroga AD, Takawale A, Armstrong EA, Yager JY, Kassiri Z, Lehner R, Vance DE, Jacobs RL. Pioglitazone attenuates hepatic inflammation and fibrosis in phosphatidylethanolamine N-methyltransferase-(PEMT) deficient mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00243.2015. PMID 26797396 DOI: 10.1152/Ajpgi.00243.2015 |
0.11 |
|
| 2018 |
Presa N, Clugston RD, Lingrell S, Kelly SE, Merrill AH, Jana S, Kassiri Z, Gómez-Muñoz A, Vance DE, Jacobs RL, van der Veen JN. Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1865: 14-25. PMID 30300671 DOI: 10.1016/J.Bbadis.2018.10.010 |
0.107 |
|
| 2017 |
van der Veen JN, Lingrell S, Gao X, Takawale A, Kassiri Z, Vance DE, Jacobs RL. Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferase. Journal of Lipid Research. PMID 28159867 DOI: 10.1194/Jlr.M070631 |
0.096 |
|
| 2016 |
Hernandez-Anzaldo S, Brglez V, Hemmeryckx B, Leung D, Filep JG, Vance JE, Vance DE, Kassiri Z, Lijnen RH, Lambeau G, Fernandez-Patron C. Novel Role for Matrix Metalloproteinase 9 in Modulation of Cholesterol Metabolism. Journal of the American Heart Association. 5. PMID 27694328 DOI: 10.1161/Jaha.116.004228 |
0.09 |
|
| 2023 |
Hu M, Meganathan I, Zhu J, MacArthur R, Kassiri Z. Loss of TIMP3, but not TIMP4, exacerbates thoracic and abdominal aortic aneurysm. Journal of Molecular and Cellular Cardiology. 184: 61-74. PMID 37844423 DOI: 10.1016/j.yjmcc.2023.10.001 |
0.09 |
|
| 2015 |
Shen M, Lee J, Basu R, Sakamuri SS, Wang X, Fan D, Kassiri Z. Divergent roles of matrix metalloproteinase 2 in pathogenesis of thoracic aortic aneurysm. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 888-98. PMID 25657308 DOI: 10.1161/ATVBAHA.114.305115 |
0.088 |
|
| 2020 |
Liu B, Granville DJ, Golledge J, Kassiri Z. Pathogenic mechanisms and the potential of drug therapies for aortic aneurysm. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32083977 DOI: 10.1152/Ajpheart.00621.2019 |
0.083 |
|
| 2014 |
Lee J, Shen M, Parajuli N, Oudit GY, McMurtry MS, Kassiri Z. Gender-dependent aortic remodelling in patients with bicuspid aortic valve-associated thoracic aortic aneurysm. Journal of Molecular Medicine (Berlin, Germany). 92: 939-49. PMID 24893666 DOI: 10.1007/s00109-014-1178-6 |
0.082 |
|
| 2021 |
Lindsey ML, Kassiri Z, Hansell Keehan K, Brunt KR, Carter JR, Kirk JA, LeBlanc AJ, Kleinbongard P, Ripplinger CM. We are the Change We Seek. American Journal of Physiology. Heart and Circulatory Physiology. PMID 33710925 DOI: 10.1152/ajpheart.00090.2021 |
0.075 |
|
| 2010 |
Oudit GY, Liu GC, Zhong J, Basu R, Chow FL, Zhou J, Loibner H, Janzek E, Schuster M, Penninger JM, Herzenberg AM, Kassiri Z, Scholey JW. Human recombinant ACE2 reduces the progression of diabetic nephropathy. Diabetes. 59: 529-38. PMID 19934006 DOI: 10.2337/Db09-1218 |
0.07 |
|
| 2022 |
Kilic T, Okuno K, Eguchi S, Kassiri Z. Disintegrin and Metalloproteinases (ADAMs [A Disintegrin and Metalloproteinase] and ADAMTSs [ADAMs With a Thrombospondin Motif]) in Aortic Aneurysm. Hypertension (Dallas, Tex. : 1979). 79: 1327-1338. PMID 35543145 DOI: 10.1161/HYPERTENSIONAHA.122.17963 |
0.07 |
|
| 2019 |
Jana S, Hu M, Shen M, Kassiri Z. Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm. Experimental & Molecular Medicine. 51: 160. PMID 31857579 DOI: 10.1038/s12276-019-0286-3 |
0.064 |
|
| 2018 |
Jana S, Kassiri Z. LOXury of Inhibiting Fibrosis in Volume Overload Cardiomyopathy Editorial Focus on Ms #H-00086-2018R2. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29856653 DOI: 10.1152/ajpheart.00315.2018 |
0.063 |
|
| 2015 |
Das SK, DesAulniers J, Dyck JR, Kassiri Z, Oudit GY. Resveratrol mediates therapeutic hepatic effects in acquired and genetic murine models of iron-overload. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 26077449 DOI: 10.1111/liv.12893 |
0.05 |
|
| 2021 |
Lindsey ML, LeBlanc AJ, Ripplinger CM, Kirk JA, Carter JR, Hansell Keehan K, Brunt KR, Kleinbongard P, Kassiri Z. Reinforcing rigor and reproducibility expectations for use of sex and gender in cardiovascular research. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34524922 DOI: 10.1152/ajpheart.00418.2021 |
0.05 |
|
| 2022 |
Lindsey ML, Carter JR, Ripplinger CM, Kassiri Z, Hansell Keehan K, Brunt KR, Kirk JA, Kleinbongard P, LeBlanc AJ. Sex Still Matters in Cardiovascular Research. American Journal of Physiology. Heart and Circulatory Physiology. PMID 36487186 DOI: 10.1152/ajpheart.00643.2022 |
0.04 |
|
| 2023 |
Zhang A, Li Y, Kassiri Z, Oudit GY. Linking Plasma LTBP-2 Levels and Clinical Outcomes in Patients with Dilated Cardiomyopathy. The Canadian Journal of Cardiology. PMID 37348759 DOI: 10.1016/j.cjca.2023.06.016 |
0.037 |
|
| 2022 |
Hu M, Kassiri Z. Function of TGFβ (Transforming Growth Factor-β) Receptor in the Vein Is Not in Vain. Arteriosclerosis, Thrombosis, and Vascular Biology. 101161ATVBAHA1223178. PMID 35616032 DOI: 10.1161/ATVBAHA.122.317861 |
0.035 |
|
| 2023 |
Zhu J, Kassiri Z. Can Good CARMA Prevent Abdominal Aortic Aneurysm? The Canadian Journal of Cardiology. PMID 37086836 DOI: 10.1016/j.cjca.2023.04.012 |
0.017 |
|
| 2023 |
Lindsey ML, Kleinbongard P, Kassiri Z, Carter JR, Hansell Keehan K, Ripplinger CM, LeBlanc AJ, Brunt KR, Kirk JA. We Asked and You Answered. American Journal of Physiology. Heart and Circulatory Physiology. PMID 36930658 DOI: 10.1152/ajpheart.00084.2023 |
0.01 |
|
| 2023 |
Lindsey ML, Kassiri Z, LeBlanc AJ, Ripplinger CM, Kirk JA, Carter JR, Kleinbongard P, Brunt KR. Spring Cleaning: Freshening up the portfolio. American Journal of Physiology. Heart and Circulatory Physiology. PMID 37115630 DOI: 10.1152/ajpheart.00219.2023 |
0.01 |
|
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