Eric B. Dammer, Ph.D. - Publications

Affiliations: 
2008 Georgia Institute of Technology, Atlanta, GA 
Area:
Molecular Biology, Genetics, Pharmacology

154/168 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ortlund E, Chen CY, Maner-Smith K, Khadka M, Ahn J, Gulbin X, Ivanova A, Dammer E, Seyfried N, Bennett D, Hajjar I. Integrative brain omics approach reveals key role for sn-1 lysophosphatidylethanolamine in Alzheimer's dementia. Research Square. PMID 38464293 DOI: 10.21203/rs.3.rs-3973736/v1  0.365
2024 Guo Q, Ping L, Dammer EB, Yin L, Xu K, Shantaraman A, Fox EJ, Golde TE, Johnson ECB, Roberts BR, Lah JJ, Levey AI, Seyfried NT. Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease. Research Square. PMID 38464223 DOI: 10.21203/rs.3.rs-3933136/v1  0.367
2024 Shantaraman A, Dammer EB, Ugochukwu O, Duong DM, Yin L, Carter EK, Gearing M, Chen-Plotkin A, Lee EB, Trojanowski JQ, Bennett DA, Lah JJ, Levey AI, Seyfried NT, Higginbotham L. Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease. Biorxiv : the Preprint Server For Biology. PMID 38328211 DOI: 10.1101/2024.01.23.576728  0.402
2024 Chung M, Carter EK, Veire AM, Dammer EB, Chang J, Duong DM, Raj N, Bassell GJ, Glass JD, Gendron TF, Nelson PT, Levey AI, Seyfried NT, McEachin ZT. Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains. Acta Neuropathologica. 147: 29. PMID 38308693 DOI: 10.1007/s00401-023-02671-0  0.307
2024 Wojtas AM, Dammer EB, Guo Q, Ping L, Shantaraman A, Duong DM, Yin L, Fox EJ, Seifar F, Lee EB, Johnson ECB, Lah JJ, Levey AI, Levites Y, Rangaraju S, et al. Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. Medrxiv : the Preprint Server For Health Sciences. PMID 38260316 DOI: 10.1101/2024.01.10.24301099  0.844
2024 Gudmundsdottir V, Frick E, Emilsson V, Jonmundsson T, Steindorsdottir A, Johnson ECB, Puerta R, Dammer E, Shantaraman A, Cano A, Boada M, Valero S, Garcia-Gonzalez P, Gudmundsson E, Gudjonsson A, et al. Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research Square. PMID 38260284 DOI: 10.21203/rs.3.rs-3706206/v1  0.307
2024 Wilson KA, Bar S, Dammer EB, Carrera EM, Hodge BA, Hilsabeck TAU, Bons J, Brownridge GW, Beck JN, Rose J, Granath-Panelo M, Nelson CS, Qi G, Gerencser AA, Lan J, et al. OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature Communications. 15: 467. PMID 38212606 DOI: 10.1038/s41467-023-44343-3  0.75
2023 Levites Y, Dammer EB, Ran Y, Tsering W, Duong D, Abreha M, Gadhavi J, Lolo K, Trejo-Lopez J, Phillips JL, Iturbe A, Erqiuzi A, Moore BD, Ryu D, Natu A, et al. Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease. Biorxiv : the Preprint Server For Biology. PMID 38076912 DOI: 10.1101/2023.11.29.568318  0.83
2023 Kapahi P, Bar S, Wilson K, Hilsabeck T, Alderfer S, Dammer E, Burton J, Shah S, Holtz A, Carrera E, Beck J, Chen J, Kauwe G, Tracy T, Seyfried N, et al. Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction. Research Square. PMID 37986935 DOI: 10.21203/rs.3.rs-3526342/v1  0.774
2023 Frick EA, Emilsson V, Jonmundsson T, Steindorsdottir AE, Johnson ECB, Puerta R, Dammer EB, Shantaraman A, Cano A, Boada M, Valero S, García-González P, Gudmundsson EF, Gudjonsson A, Loureiro JJ, et al. Serum proteomics reveals dependent and independent protein signatures in Alzheimer's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 37986771 DOI: 10.1101/2023.11.08.23298251  0.691
2023 Dammer EB, Shantaraman A, Ping L, Duong DM, Gerasimov ES, Ravindran SP, Gudmundsdottir V, Frick EA, Gomez GT, Walker KA, Emilsson V, Jennings LL, Gudnason V, Western D, Cruchaga C, et al. Proteomic Network Analysis of Alzheimer's Disease Cerebrospinal Fluid Reveals Alterations Associated with ε4 Genotype and Atomoxetine Treatment. Medrxiv : the Preprint Server For Health Sciences. PMID 37961720 DOI: 10.1101/2023.10.29.23297651  0.733
2023 Hurst CD, Dunn AR, Dammer EB, Duong DM, Shapley SM, Seyfried NT, Kaczorowski CC, Johnson ECB. Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome. Frontiers in Aging Neuroscience. 15: 1239116. PMID 37901791 DOI: 10.3389/fnagi.2023.1239116  0.82
2023 Higginbotham L, Carter EK, Dammer EB, Haque RU, Johnson ECB, Duong DM, Yin L, De Jager PL, Bennett DA, Felsky D, Tio ES, Lah JJ, Levey AI, Seyfried NT. Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment. Neurobiology of Disease. 106286. PMID 37689213 DOI: 10.1016/j.nbd.2023.106286  0.672
2023 de Ávila C, Suazo C, Nolz J, Cochran JN, Wang Q, Velazquez R, Dammer E, Readhead B, Mastroeni D. Reduced gene expression in neocortical and limbic brain regions in female Alzheimer's patients correlates with cognitive and neuropathological phenotypes. Biorxiv : the Preprint Server For Biology. PMID 37645898 DOI: 10.1101/2023.08.14.553279  0.318
2023 Borkowski K, Seyfried NT, Arnold M, Lah JJ, Levey AI, Hales CM, Dammer EB, Blach C, Louie G, Kaddurah-Daouk R, Newman JW. Integration of plasma and CSF metabolomics with CSF proteomic reveals novel associations between lipid mediators and central nervous system vascular and energy metabolism. Scientific Reports. 13: 13752. PMID 37612324 DOI: 10.1038/s41598-023-39737-8  0.713
2023 Modeste ES, Ping L, Watson CM, Duong DM, Dammer EB, Johnson ECB, Roberts BR, Lah JJ, Levey AI, Seyfried NT. Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer's disease. Molecular Neurodegeneration. 18: 48. PMID 37468915 DOI: 10.1186/s13024-023-00638-z  0.815
2023 Sung YJ, Yang C, Norton J, Johnson M, Fagan A, Bateman RJ, Perrin RJ, Morris JC, Farlow MR, Chhatwal JP, Schofield PR, Chui H, Wang F, Novotny B, Eteleeb A, ... ... Dammer EB, et al. Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease. Science Translational Medicine. 15: eabq5923. PMID 37406134 DOI: 10.1126/scitranslmed.abq5923  0.73
2023 Hurst CD, Dunn AR, Dammer EB, Duong DM, Seyfried NT, Kaczorowski CC, Johnson ECB. Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome. Biorxiv : the Preprint Server For Biology. PMID 37398142 DOI: 10.1101/2023.06.12.544646  0.82
2023 Pybus AF, Bitarafan S, Brothers RO, Rohrer A, Khaitan A, Moctezuma FR, Udeshi K, Davies B, Triplett S, Dammer E, Rangaraju S, Buckley EM, Wood LB. Profiling the neuroimmune cascade in 3xTg mice exposed to successive mild traumatic brain injuries. Biorxiv : the Preprint Server For Biology. PMID 37397993 DOI: 10.1101/2023.06.13.544838  0.793
2023 Kumar P, Goettemoeller AM, Espinosa-Garcia C, Tobin BR, Tfaily A, Nelson RS, Natu A, Dammer EB, Santiago JV, Malepati S, Cheng L, Xiao H, Duong D, Seyfried NT, Wood LB, et al. Native-state proteomics of Parvalbumin interneurons identifies novel molecular signatures and metabolic vulnerabilities to early Alzheimer's disease pathology. Biorxiv : the Preprint Server For Biology. PMID 37292756 DOI: 10.1101/2023.05.17.541038  0.832
2023 Wynne ME, Ogunbona O, Lane AR, Gokhale A, Zlatic SA, Xu C, Wen Z, Duong DM, Rayaprolu S, Ivanova A, Ortlund EA, Dammer EB, Seyfried NT, Roberts BR, Crocker A, et al. APOE expression and secretion are modulated by mitochondrial dysfunction. Elife. 12. PMID 37171075 DOI: 10.7554/eLife.85779  0.802
2023 Watson CM, Dammer EB, Ping L, Duong DM, Modeste E, Carter EK, Johnson ECB, Levey AI, Lah JJ, Roberts BR, Seyfried NT. Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific Data. 10: 261. PMID 37160957 DOI: 10.1038/s41597-023-02158-3  0.833
2023 Dammer EB, Seyfried NT, Johnson ECB. Batch Correction and Harmonization of -Omics Datasets with a Tunable Median Polish of Ratio. Frontiers in Systems Biology. 3. PMID 37122388 DOI: 10.3389/fsysb.2023.1092341  0.61
2023 Sunna S, Bowen C, Zeng H, Rayaprolu S, Kumar P, Bagchi P, Dammer EB, Guo Q, Duong DM, Bitarafan S, Natu A, Wood L, Seyfried NT, Rangaraju S. Cellular proteomic profiling using proximity labelling by TurboID-NES in microglial and neuronal cell lines. Molecular & Cellular Proteomics : McP. 100546. PMID 37061046 DOI: 10.1016/j.mcpro.2023.100546  0.8
2023 Walker CK, Greathouse KM, Tuscher JJ, Dammer EB, Weber AJ, Liu E, Curtis KA, Boros BD, Freeman CD, Seo JV, Ramdas R, Hurst C, Duong DM, Gearing M, Murchison CF, et al. Cross-Platform Synaptic Network Analysis of Human Entorhinal Cortex Identifies TWF2 as a Modulator of Dendritic Spine Length. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 37055180 DOI: 10.1523/JNEUROSCI.2102-22.2023  0.833
2023 Hurst C, Pugh DA, Abreha MH, Duong DM, Dammer EB, Bennett DA, Herskowitz JH, Seyfried NT. Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer's Disease. Molecular & Cellular Proteomics : McP. 100542. PMID 37024090 DOI: 10.1016/j.mcpro.2023.100542  0.835
2023 Čarna M, Novotny JS, Dragišić N, Slavik H, Sheardova K, Geda YE, Vyhnalek M, Laczo J, Hort J, Mao Z, Rissman RA, Hajduch M, Dammer EB, Stokin GB. Missorting of Plasma miRNAs in Aging and Alzheimer's Disease. Journal of Neurochemistry. PMID 36892419 DOI: 10.1111/jnc.15801  0.72
2023 Čarna M, Onyango IG, Katina S, Holub D, Novotny JS, Nezvedova M, Jha D, Nedelska Z, Lacovich V, Vyvere TV, Houbrechts R, Garcia-Mansfield K, Sharma R, David-Dirgo V, Vyhnalek M, ... ... Dammer EB, et al. Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36825691 DOI: 10.1002/alz.12970  0.827
2022 Del Campo M, Peeters CFW, Johnson ECB, Vermunt L, Hok-A-Hin YS, van Nee M, Chen-Plotkin A, Irwin DJ, Hu WT, Lah JJ, Seyfried NT, Dammer EB, Herradon G, Meeter LH, van Swieten J, et al. CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature Aging. 2: 1040-1053. PMID 37118088 DOI: 10.1038/s43587-022-00300-1  0.717
2022 Dammer EB, Ping L, Duong DM, Modeste ES, Seyfried NT, Lah JJ, Levey AI, Johnson ECB. Multi-platform proteomic analysis of Alzheimer's disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome. Alzheimer's Research & Therapy. 14: 174. PMID 36384809 DOI: 10.1186/s13195-022-01113-5  0.829
2022 Ponnusamy M, Wang S, Yuksel M, Hansen MT, Blazier DM, McMillan JD, Zhang X, Dammer EB, Collier L, Thinakaran G. Loss of forebrain BIN1 attenuates hippocampal pathology and neuroinflammation in a tauopathy model. Brain : a Journal of Neurology. PMID 36059072 DOI: 10.1093/brain/awac318  0.322
2022 Nelson RS, Dammer EB, Santiago JV, Seyfried NT, Rangaraju S. Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms. Frontiers in Neuroscience. 16: 902146. PMID 35784845 DOI: 10.3389/fnins.2022.902146  0.818
2022 Olah VJ, Goettemoeller AM, Rayaprolu S, Dammer EB, Seyfried NT, Rangaraju S, Dimidschstein J, Rowan MJM. Biophysical Kv3 channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer's. Elife. 11. PMID 35727131 DOI: 10.7554/eLife.75316  0.817
2022 Adebayo OO, Dammer EB, Dill CD, Adebayo AO, Oseni SO, Griffen TL, Ohandjo AQ, Yan F, Jain S, Barwick BG, Singh R, Boise LH, Lillard JW. Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients. Cancers. 14. PMID 35565356 DOI: 10.3390/cancers14092228  0.772
2022 Zhang H, Dammer EB, Duong DM, Danelia D, Seyfried NT, Yu DS. Quantitative proteomic analysis of the lysine acetylome reveals diverse SIRT2 substrates. Scientific Reports. 12: 3822. PMID 35264593 DOI: 10.1038/s41598-022-06793-5  0.699
2022 Johnson ECB, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, et al. Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level. Nature Neuroscience. 25: 213-225. PMID 35115731 DOI: 10.1038/s41593-021-00999-y  0.803
2021 Levey AI, Qiu D, Zhao L, Hu WT, Duong DM, Higginbotham L, Dammer EB, Seyfried NT, Wingo TS, Hales CM, Gámez Tansey M, Goldstein DS, Abrol A, Calhoun VD, Goldstein FC, et al. A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment. Brain : a Journal of Neurology. PMID 34919634 DOI: 10.1093/brain/awab452  0.73
2021 Haytural H, Benfeitas R, Schedin-Weiss S, Bereczki E, Rezeli M, Unwin RD, Wang X, Dammer EB, Johnson ECB, Seyfried NT, Winblad B, Tijms BM, Visser PJ, Frykman S, Tjernberg LO. Insights into the changes in the proteome of Alzheimer disease elucidated by a meta-analysis. Scientific Data. 8: 312. PMID 34862388 DOI: 10.1038/s41597-021-01090-8  0.746
2021 Ma Y, Dammer EB, Felsky D, Duong DM, Klein HU, White CC, Zhou M, Logsdon BA, McCabe C, Xu J, Wang M, Wingo TS, Lah JJ, Zhang B, Schneider J, et al. Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue. Nature Communications. 12: 7035. PMID 34857756 DOI: 10.1038/s41467-021-27204-9  0.792
2021 Kundinger SR, Dammer EB, Yin L, Hurst C, Shapley S, Ping L, Khoshnevis S, Ghalei H, Duong DM, Seyfried NT. Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization. The Journal of Biological Chemistry. 101306. PMID 34673031 DOI: 10.1016/j.jbc.2021.101306  0.796
2021 Borkowski K, Pedersen TL, Seyfried NT, Lah JJ, Levey AI, Hales CM, Dammer EB, Blach C, Louie G, Kaddurah-Daouk R, Newman JW. Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer's disease. Alzheimer's Research & Therapy. 13: 149. PMID 34488866 DOI: 10.1186/s13195-021-00893-6  0.708
2021 Lagomarsino VN, Pearse RV, Liu L, Hsieh YC, Fernandez MA, Vinton EA, Paull D, Felsky D, Tasaki S, Gaiteri C, Vardarajan B, Lee H, Muratore CR, Benoit CR, Chou V, ... ... Dammer EB, et al. Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors. Neuron. PMID 34473944 DOI: 10.1016/j.neuron.2021.08.003  0.732
2021 Griffen TL, Dammer EB, Dill CD, Carey KM, Young CD, Nunez SK, Ohandjo AQ, Kornblau SM, Lillard JW. Multivariate transcriptome analysis identifies networks and key drivers of chronic lymphocytic leukemia relapse risk and patient survival. Bmc Medical Genomics. 14: 171. PMID 34187466 DOI: 10.1186/s12920-021-01012-y  0.758
2021 Gutierrez-Quiceno L, Dammer EB, Johnson AG, Webster JA, Shah R, Duong D, Yin L, Seyfried NT, Alvarez VE, Stein TD, McKee AC, Hales CM. A proteomic network approach resolves stage-specific molecular phenotypes in chronic traumatic encephalopathy. Molecular Neurodegeneration. 16: 40. PMID 34172091 DOI: 10.1186/s13024-021-00462-3  0.7
2021 Dill CD, Dammer EB, Griffen TL, Seyfried NT, Lillard JW. A network approach reveals driver genes associated with survival of patients with triple-negative breast cancer. Iscience. 24: 102451. PMID 34007962 DOI: 10.1016/j.isci.2021.102451  0.774
2021 Donovan LE, Dammer EB, Duong DM, Hanfelt JJ, Levey AI, Seyfried NT, Lah JJ. Correction to: Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease. Alzheimer's Research & Therapy. 13: 102. PMID 34006317 DOI: 10.1186/s13195-021-00839-y  0.652
2021 Abreha MH, Ojelade S, Dammer EB, McEachin ZT, Duong DM, Gearing M, Bassell GJ, Lah JJ, Levey AI, Shulman JM, Seyfried NT. TBK1 interacts with tau and enhances neurodegeneration in tauopathy. The Journal of Biological Chemistry. 100760. PMID 33965374 DOI: 10.1016/j.jbc.2021.100760  0.699
2021 Wingo TS, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Lori A, Kim PJ, Ressler KJ, Beach TG, Reiman EM, Epstein MP, De Jager PL, Lah JJ, et al. Brain proteome-wide association study implicates novel proteins in depression pathogenesis. Nature Neuroscience. PMID 33846625 DOI: 10.1038/s41593-021-00832-6  0.641
2021 Guo Q, Dammer EB, Zhou M, Kundinger SR, Gearing M, Lah JJ, Levey AI, Shulman JM, Seyfried NT. Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease. Frontiers in Molecular Neuroscience. 14: 623659. PMID 33815056 DOI: 10.3389/fnmol.2021.623659  0.827
2021 Chen MJ, Ramesha S, Weinstock LD, Gao T, Ping L, Xiao H, Dammer EB, Duong DD, Levey AI, Lah JJ, Seyfried NT, Wood LB, Rangaraju S. Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease. Journal of Neuroscience Research. PMID 33729626 DOI: 10.1002/jnr.24829  0.828
2021 Ramesha S, Rayaprolu S, Bowen CA, Giver CR, Bitarafan S, Nguyen HM, Gao T, Chen MJ, Nwabueze N, Dammer EB, Engstrom AK, Xiao H, Pennati A, Seyfried NT, Katz DJ, et al. Unique molecular characteristics and microglial origin of Kv1.3 channel-positive brain myeloid cells in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33649184 DOI: 10.1073/pnas.2013545118  0.813
2021 Robins C, Liu Y, Fan W, Duong DM, Meigs J, Harerimana NV, Gerasimov ES, Dammer EB, Cutler DJ, Beach TG, Reiman EM, De Jager PL, Bennett DA, Lah JJ, Wingo AP, et al. Genetic control of the human brain proteome. American Journal of Human Genetics. PMID 33571421 DOI: 10.1016/j.ajhg.2021.01.012  0.689
2021 Wingo AP, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Robins C, Beach TG, Reiman EM, Epstein MP, De Jager PL, Lah JJ, Bennett DA, Seyfried NT, et al. Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis. Nature Genetics. PMID 33510477 DOI: 10.1038/s41588-020-00773-z  0.723
2021 Li HD, Funk CC, McFarland K, Dammer EB, Allen M, Carrasquillo MM, Levties Y, Chakrabarty P, Burgess JD, Wang X, Dickson D, Seyfried NT, Duong DM, Lah JJ, Younkin SG, et al. Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33480174 DOI: 10.1002/alz.12254  0.722
2020 Sarkar S, Murphy MA, Dammer EB, Olsen AL, Rangaraju S, Fraenkel E, Feany MB. Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy. Npj Parkinson's Disease. 6: 40. PMID 33311497 DOI: 10.1038/s41531-020-00143-w  0.768
2020 Higginbotham L, Ping L, Dammer EB, Duong DM, Zhou M, Gearing M, Hurst C, Glass JD, Factor SA, Johnson ECB, Hajjar I, Lah JJ, Levey AI, Seyfried NT. Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease. Science Advances. 6. PMID 33087358 DOI: 10.1126/sciadv.aaz9360  0.838
2020 Huang M, Modeste E, Dammer E, Merino P, Taylor G, Duong DM, Deng Q, Holler CJ, Gearing M, Dickson D, Seyfried NT, Kukar T. Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations. Acta Neuropathologica Communications. 8: 163. PMID 33028409 DOI: 10.1186/s40478-020-01037-x  0.829
2020 Mangleburg CG, Wu T, Yalamanchili HK, Guo C, Hsieh YC, Duong DM, Dammer EB, De Jager PL, Seyfried NT, Liu Z, Shulman JM. Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Molecular Neurodegeneration. 15: 56. PMID 32993812 DOI: 10.1186/s13024-020-00405-4  0.705
2020 Beckmann ND, Lin WJ, Wang M, Cohain AT, Charney AW, Wang P, Ma W, Wang YC, Jiang C, Audrain M, Comella PH, Fakira AK, Hariharan SP, Belbin GM, Girdhar K, ... ... Dammer EB, et al. Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease. Nature Communications. 11: 3942. PMID 32770063 DOI: 10.1038/S41467-020-17405-Z  0.744
2020 Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, ... ... Dammer EB, et al. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Reports. 32: 107908. PMID 32668255 DOI: 10.1016/J.Celrep.2020.107908  0.486
2020 Swarup V, Chang TS, Duong DM, Dammer EB, Dai J, Lah JJ, Johnson ECB, Seyfried NT, Levey AI, Geschwind DH. Identification of Conserved Proteomic Networks in Neurodegenerative Dementia. Cell Reports. 31: 107807. PMID 32579933 DOI: 10.1016/J.Celrep.2020.107807  0.758
2020 Wingo AP, Fan W, Duong DM, Gerasimov ES, Dammer EB, Liu Y, Harerimana NV, White B, Thambisetty M, Troncoso JC, Kim N, Schneider JA, Hajjar IM, Lah JJ, Bennett DA, et al. Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. Nature Neuroscience. PMID 32576978 DOI: 10.1038/S41593-020-0662-2  0.703
2020 Zhou M, Haque RU, Dammer EB, Duong DM, Ping L, Johnson ECB, Lah JJ, Levey AI, Seyfried NT. Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer's disease. Clinical Proteomics. 17: 19. PMID 32514259 DOI: 10.1186/S12014-020-09285-8  0.819
2020 Wingo AP, Fan W, Duong DM, Gerasimov ES, Dammer EB, Liu Y, Harerimana NV, White B, Thambisetty M, Troncoso JC, Kim N, Schneider JA, Hajjar IM, Lah JJ, Bennett DA, et al. Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. Nature Neuroscience. PMID 32424284 DOI: 10.1038/S41593-020-0635-5  0.71
2020 Rayaprolu S, Gao T, Xiao H, Ramesha S, Weinstock LD, Shah J, Duong DM, Dammer EB, Webster JA, Lah JJ, Wood LB, Betarbet R, Levey AI, Seyfried NT, Rangaraju S. Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease. Molecular Neurodegeneration. 15: 28. PMID 32381088 DOI: 10.1186/S13024-020-00377-5  0.82
2020 Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, et al. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature Medicine. PMID 32284590 DOI: 10.1038/S41591-020-0815-6  0.847
2020 Sarkar S, Dammer EB, Malovic E, Olsen AL, Raza SA, Gao T, Xiao H, Oliver DL, Duong D, Joers V, Seyfried N, Huang M, Kukar T, Tansey MG, Kanthasamy AG, et al. Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells. Frontiers in Immunology. 11: 33. PMID 32082315 DOI: 10.1096/Fasebj.2020.34.S1.00630  0.803
2020 Kundinger SR, Bishof I, Dammer EB, Duong DM, Seyfried NT. Middle-Down Proteomics Reveals Dense Sites of Methylation and Phosphorylation in Arginine-Rich RNA-Binding Proteins. Journal of Proteome Research. PMID 31994892 DOI: 10.1021/Acs.Jproteome.9B00633  0.783
2020 Nguyen TT, Dammer EB, Owino SA, Giddens MM, Madaras NS, Duong DM, Seyfried NT, Hall RA. Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1. Journal of Proteome Research. PMID 31903766 DOI: 10.1021/Acs.Jproteome.9B00622  0.71
2020 Frank F, Kavousi N, Bountali A, Dammer E, Mourtada-Maarabouni M, Ortlund E. SAT-LB138 The LncRNA Growth Arrest Specific 5 Regulates Cell Survival via Distinct Structural Modules With Independent Functions Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.2327  0.321
2020 Adebayo OO, Griffen T, Young C, Dammer E, Lillard JW. Abstract 4388: Weighted gene co-expression network analysis identified cell cycle signaling pathway associated hub genes correlated with progression and prognosis of multiple myeloma Cancer Research. 80: 4388-4388. DOI: 10.1158/1538-7445.Am2020-4388  0.792
2020 Wingo TS, Liu Y, Lori A, Gerasimov ES, Duong DM, Dammer E, Ressler K, Lah J, Bennett D, Seyfried NT, Levey AI, Wingo A. Human Brain Proteome-Wide Association Study of Depression Identified 24 Proteins as Tractable Targets for Further Mechanistic Studies Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.480  0.682
2019 Ohandjo AQ, Liu Z, Dammer EB, Dill CD, Griffen TL, Carey KM, Hinton DE, Meller R, Lillard JW. Transcriptome Network Analysis Identifies CXCL13-CXCR5 Signaling Modules in the Prostate Tumor Immune Microenvironment. Scientific Reports. 9: 14963. PMID 31628349 DOI: 10.1038/S41598-019-46491-3  0.782
2019 Hsieh YC, Guo C, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, De Jager PL, Seyfried NT, Liu Z, Shulman JM. Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Reports. 29: 301-316.e10. PMID 31597093 DOI: 10.1016/J.Celrep.2019.08.104  0.744
2019 Werner E, Alter A, Deng Q, Dammer EB, Wang Y, Yu DS, Duong DM, Seyfried NT, Doetsch PW. Ionizing Radiation induction of cholesterol biosynthesis in Lung tissue. Scientific Reports. 9: 12546. PMID 31467399 DOI: 10.1038/S41598-019-48972-X  0.643
2019 Higginbotham L, Dammer EB, Duong DM, Modeste E, Montine TJ, Lah JJ, Levey AI, Seyfried NT. Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease. Proteomes. 7. PMID 31461916 DOI: 10.3390/Proteomes7030030  0.831
2019 Gao T, Jernigan J, Raza SA, Dammer EB, Xiao H, Seyfried NT, Levey AI, Rangaraju S. Transcriptional regulation of homeostatic and disease-associated-microglial genes by IRF1, LXRβ, and CEBPα. Glia. PMID 31301160 DOI: 10.1002/Glia.23678  0.782
2019 Zhang YQ, Tang YB, Dammer E, Liu JR, Zhao YW, Zhu L, Ren RJ, Chen HZ, Wang G, Cheng Q. Dysregulated Urinary Arginine Metabolism in Older Adults With Amnestic Mild Cognitive Impairment. Frontiers in Aging Neuroscience. 11: 90. PMID 31105552 DOI: 10.3389/Fnagi.2019.00090  0.335
2019 Gerber KJ, Dammer EB, Duong DM, Deng Q, Dudek SM, Seyfried NT, Hepler JR. Specific Proteomes of Hippocampal Regions CA2 and CA1 Reveal Proteins Linked to the Unique Physiology of Area CA2. Journal of Proteome Research. PMID 31059263 DOI: 10.1021/Acs.Jproteome.9B00103  0.647
2019 Wingo AP, Dammer EB, Breen MS, Logsdon BA, Duong DM, Troncosco JC, Thambisetty M, Beach TG, Serrano GE, Reiman EM, Caselli RJ, Lah JJ, Seyfried NT, Levey AI, Wingo TS. Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age. Nature Communications. 10: 1619. PMID 30962425 DOI: 10.1038/S41467-019-09613-Z  0.672
2019 Gao Y, Ren RJ, Zhong ZL, Dammer E, Zhao QH, Shan S, Zhou Z, Li X, Zhang YQ, Cui HL, Hu YB, Chen SD, Chen JJ, Guo QH, Wang G. Mutation profile of APP, PSEN1, and PSEN2 in Chinese familial Alzheimer's disease. Neurobiology of Aging. 77: 154-157. PMID 30822634 DOI: 10.1016/J.Neurobiolaging.2019.01.018  0.332
2019 Wingo AP, Dammer EB, Breen MS, Logsdon BA, Duong D, Troncoso JC, Thambisetty M, Beach TG, Serrano GE, Reiman EM, Caselli RJ, Lah JJ, Seyfried NT, Levey AI, Wingo TS. O4-10-04: LARGE-SCALE PROTEOMIC ANALYSIS OF HUMAN PREFRONTAL CORTEX IDENTIFIES PROTEINS ASSOCIATED WITH COGNITIVE TRAJECTORY IN ADVANCED AGE Alzheimer's & Dementia. 15: P1260-P1260. DOI: 10.1016/J.Jalz.2019.06.4797  0.66
2019 Ping L, Higginbotham LA, Dammer EB, Duong D, Zhou M, Wingo TS, Johnson EC, Lah JJ, Levey AI, Seyfried NT. INTEGRATIVE PROTEOMICS LINKS CEREBROSPINAL FLUID BIOMARKERS TO PATHOLOGICAL NETWORKS IN THE ALZHEIMER’S DISEASE BRAIN Alzheimer's & Dementia. 15: P191. DOI: 10.1016/J.Jalz.2019.06.4517  0.781
2019 Guo C, Hsieh Y, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, Jager PLD, Seyfried NT, Liu Z, Shulman JM. P4-130: Tau-Mediated Disruption Of The Spliceosome Triggers Cryptic Rna Splicing And Neurodegeneration In Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3791  0.701
2019 Modeste ES, Dammer EB, Duong D, Lah JJ, Levey AI, Wingo AP, Wingo TS, Seyfried NT. P4-115: SEX-SPECIFIC PROTEIN DIFFERENCES LINKED TO ALZHEIMER'S DISEASE RISK UNCOVERED BY A COEXPRESSION-REGRESSION FRAMEWORK Alzheimer's & Dementia. 15: P1320-P1320. DOI: 10.1016/J.Jalz.2019.06.3776  0.81
2019 Johnson ECB, Dammer EB, Duong D, Yin L, Thambisetty M, Troncoso JC, Lah JJ, Levey AI, Seyfried NT. P2-218: Deep Proteomic Network Analysis Of Alzheimer'S Disease Brain Reveals Alterations In Rna Binding Proteins And Rna Splicing Associated With Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2625  0.722
2019 Wingo A, Fan W, Seyfried N, Duong D, Dammer E, Bennett D, Lah J, Levey A, Wingo T. F94. Human Brain Proteome-Wide Association Study of Longitudinally Assessed Late-Life Depression Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.631  0.645
2018 Dai J, Johnson ECB, Dammer EB, Duong DM, Gearing M, Lah JJ, Levey AI, Wingo TS, Seyfried NT. Effects of Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease. Frontiers in Molecular Neuroscience. 11: 454. PMID 30618606 DOI: 10.3389/Fnmol.2018.00454  0.726
2018 Johnson ECB, Dammer EB, Duong DM, Yin L, Thambisetty M, Troncoso JC, Lah JJ, Levey AI, Seyfried NT. Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease. Molecular Neurodegeneration. 13: 52. PMID 30286791 DOI: 10.1186/S13024-018-0282-4  0.772
2018 Abreha MH, Dammer EB, Ping L, Zhang T, Duong DM, Gearing M, Lah JJ, Levey AI, Seyfried NT. Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease. Proteomics. e1800108. PMID 30230243 DOI: 10.1002/Pmic.201800108  0.751
2018 Wang M, Beckmann ND, Roussos P, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF, Hauberg ME, Bendl J, Peters MA, Logsdon B, Wang P, ... ... Dammer EB, et al. The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease. Scientific Data. 5: 180185. PMID 30204156 DOI: 10.1038/Sdata.2018.185  0.718
2018 Rangaraju S, Dammer EB, Raza SA, Gao T, Xiao H, Betarbet R, Duong DM, Webster JA, Hales CM, Lah JJ, Levey AI, Seyfried NT. Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins. Molecular Neurodegeneration. 13: 34. PMID 29954413 DOI: 10.1186/S13024-018-0266-4  0.819
2018 Bishof I, Dammer EB, Duong DM, Kundinger S, Gearing M, Lah JJ, Levey AI, Seyfried NT. RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease. The Journal of Biological Chemistry. PMID 29802200 DOI: 10.1074/Jbc.Ra118.001747  0.792
2018 Rangaraju S, Dammer EB, Raza SA, Rathakrishnan P, Xiao H, Gao T, Duong DM, Pennington MW, Lah JJ, Seyfried NT, Levey AI. Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease. Molecular Neurodegeneration. 13: 24. PMID 29784049 DOI: 10.1186/S13024-018-0254-8  0.824
2018 Rangaraju S, Raza SA, Li NX, Betarbet R, Dammer EB, Duong D, Lah JJ, Seyfried NT, Levey AI. Differential Phagocytic Properties of CD45Microglia and CD45Brain Mononuclear Phagocytes-Activation and Age-Related Effects. Frontiers in Immunology. 9: 405. PMID 29552013 DOI: 10.3389/Fimmu.2018.00405  0.826
2018 Evans PR, Gerber KJ, Dammer EB, Duong DM, Goswami D, Lustberg DJ, Zou J, Yang JJ, Dudek SM, Griffin PR, Seyfried NT, Hepler JR. Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner. Journal of Proteome Research. PMID 29518331 DOI: 10.1021/Acs.Jproteome.8B00027  0.696
2017 Umoh ME, Dammer EB, Dai J, Duong DM, Lah JJ, Levey AI, Gearing M, Glass JD, Seyfried NT. A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain. Embo Molecular Medicine. PMID 29191947 DOI: 10.15252/Emmm.201708202  0.809
2017 Cherry JD, Zeineddin A, Dammer EB, Webster JA, Duong D, Seyfried NT, Levey AI, Alvarez VE, Huber BR, Stein TD, Kiernan PT, McKee AC, Lah JJ, Hales CM. Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy. Journal of Neuropathology and Experimental Neurology. PMID 29145658 DOI: 10.1093/Jnen/Nlx100  0.77
2017 McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, et al. Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease. Molecular Neurodegeneration. 12: 82. PMID 29110684 DOI: 10.1186/S13024-017-0219-3  0.705
2017 Allen M, Wang X, Burgess JD, Watzlawik J, Serie DJ, Younkin CS, Nguyen T, Malphrus KG, Lincoln S, Carrasquillo MM, Ho C, Chakrabarty P, Strickland S, Murray ME, Swarup V, ... ... Dammer EB, et al. Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29107053 DOI: 10.1016/J.Jalz.2017.09.012  0.737
2017 An Y, Varma VR, Varma S, Casanova R, Dammer E, Pletnikova O, Chia CW, Egan JM, Ferrucci L, Troncoso J, Levey A, Lah J, Seyfried N, Legido-Quigley C, O'Brien R, et al. Evidence for brain glucose dysregulation in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29055815 DOI: 10.1016/J.Jalz.2017.09.011  0.715
2017 Wingo TS, Duong DM, Zhou M, Dammer EB, Wu H, Cutler DJ, Lah JJ, Levey AI, Seyfried NT. Integrating Next-Generation Genomic Sequencing and Mass Spectrometry to Estimate Allele-Specific Protein Abundance in Human Brain. Journal of Proteome Research. PMID 28691493 DOI: 10.1021/Acs.Jproteome.7B00324  0.775
2017 Rangaraju S, Raza SA, Pennati A, Deng Q, Dammer EB, Duong D, Pennington MW, Tansey MG, Lah JJ, Betarbet R, Seyfried NT, Levey AI. A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation. Journal of Neuroinflammation. 14: 128. PMID 28651603 DOI: 10.1186/S12974-017-0906-6  0.779
2017 Cutler AA, Dammer EB, Doung DM, Seyfried NT, Corbett AH, Pavlath GK. Biochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging. Aging Cell. PMID 28544616 DOI: 10.1111/Acel.12604  0.662
2017 Li Y, Dammer EB, Zhang-Brotzge X, Chen S, Duong DM, Seyfried NT, Kuan CY, Sun YY. Osteopontin Is a Blood Biomarker for Microglial Activation and Brain Injury in Experimental Hypoxic-Ischemic Encephalopathy. Eneuro. 4. PMID 28101531 DOI: 10.1523/ENEURO.0253-16.2016  0.646
2017 Seyfried NT, Dammer EB, Duong DM, Deng Q, Troncoso JC, Thambisetty M, Lah JJ, Levey AI. PROTEIN CO-EXPRESSION NETWORK ANALYSIS IN ASYMPTOMATIC AND SYMPTOMATIC ALZHEIMER'S DISEASE Alzheimer's & Dementia. 13: P554-P555. DOI: 10.1016/J.Jalz.2017.07.155  0.731
2016 Seyfried NT, Dammer EB, Swarup V, Nandakumar D, Duong DM, Yin L, Deng Q, Nguyen T, Hales CM, Wingo T, Glass J, Gearing M, Thambisetty M, Troncoso JC, Geschwind DH, et al. A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease. Cell Systems. PMID 27989508 DOI: 10.1016/J.Cels.2016.11.006  0.762
2016 Varma VR, Varma S, An Y, Hohman TJ, Seddighi S, Casanova R, Beri A, Dammer EB, Seyfried NT, Pletnikova O, Moghekar A, Wilson MR, Lah JJ, O'Brien RJ, Levey AI, et al. Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway. Molecular Psychiatry. PMID 27872486 DOI: 10.1038/Mp.2016.206  0.752
2016 Hales CM, Dammer EB, Deng Q, Duong DM, Gearing M, Troncoso JC, Thambisetty M, Lah JJ, Shulman JM, Levey AI, Seyfried NT. Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression. Proteomics. PMID 27718298 DOI: 10.1002/Pmic.201600057  0.739
2016 Zhang B, Wang LL, Ren RJ, Dammer EB, Zhang YF, Huang Y, Di Chen S, Wang G. MicroRNA-146a represses LRP2 translation and leads to cell apoptosis in Alzheimer's disease. Febs Letters. PMID 27241555 DOI: 10.1002/1873-3468.12229  0.331
2016 Owings JP, Kuiper EG, Prezioso SM, Meisner J, Varga JJ, Zelinskaya N, Dammer EB, Duong DM, Seyfried NT, Albertí S, Conn GL, Goldberg JB. Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase. The Journal of Biological Chemistry. 291: 3280-90. PMID 26677219 DOI: 10.1074/Jbc.M115.706853  0.64
2016 Seyfried NT, Ping L, Dammer EB, Duong DM, Gearing M, Deng Q, Lah JJ, Levey AI. O5-06-02: Proteomic Network Analysis to Find Common Mechanisms Underlying Alzheimer's Disease and PD Alzheimer's & Dementia. 12: P390-P391. DOI: 10.1016/J.Jalz.2016.06.736  0.682
2016 Levey AI, Dammer EB, Duong DM, Lah JJ, Seyfried NT. Discovery Of Novel Proteomic Targets For Treatment Of Alzheimer'S Disease Alzheimers & Dementia. 12: 215. DOI: 10.1016/J.Jalz.2016.06.382  0.697
2016 Varma VR, Varma S, An Y, Beri A, Dammer EB, Seyfried NT, Moghekar A, Wilson M, Lah JJ, O’Brien R, Levey AI, Troncoso JC, Albert MS, Thambisetty M. The Acute Phase Protein Alpha-2-Macroglobulin Predicts Risk Of Incident Alzheimer'S Disease And Modulates Tau Pathology Through The Rcan1-Calcineurin Pathway Alzheimers & Dementia. 12: 745. DOI: 10.1016/J.Jalz.2016.06.1554  0.697
2015 Ren RJ, Zhang YF, Dammer EB, Zhou Y, Wang LL, Liu XH, Feng BL, Jiang GX, Chen SD, Wang G, Cheng Q. Peripheral Blood MicroRNA Expression Profiles in Alzheimer's Disease: Screening, Validation, Association with Clinical Phenotype and Implications for Molecular Mechanism. Molecular Neurobiology. PMID 26497032 DOI: 10.1007/S12035-015-9484-8  0.35
2015 Hu YB, Dammer EB, Ren RJ, Wang G. The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration. Translational Neurodegeneration. 4: 18. PMID 26448863 DOI: 10.1186/S40035-015-0041-1  0.379
2015 Dammer EB, Göttle M, Duong DM, Hanfelt J, Seyfried NT, Jinnah HA. Consequences of impaired purine recycling on the proteome in a cellular model of Lesch-Nyhan disease. Molecular Genetics and Metabolism. 114: 570-9. PMID 25769394 DOI: 10.1016/J.Ymgme.2015.02.007  0.701
2015 Dammer EB, Lee AK, Duong DM, Gearing M, Lah JJ, Levey AI, Seyfried NT. Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins. Proteomics. 15: 508-19. PMID 25332170 DOI: 10.1002/Pmic.201400189  0.742
2015 Dammer EB, Ren R, Duong DM, Lee AK, Gearing M, Lah JJ, Levey AI, Seyfried NT. O4-12-03: Brain phosphoproteome network analysis discriminates Alzheimer's disease from other tauopathies Alzheimer's & Dementia. 11: P300-P300. DOI: 10.1016/J.Jalz.2015.07.415  0.705
2015 Dammer EB, Duong DM, Yin L, Swarup V, Parikshak N, Coppola G, Geschwind DH, Troncoso JC, Thambisetty M, Seyfried NT, Lah JJ, Levey AI. O4-12-02: Protein co-expression network analysis in Alzheimer's disease Alzheimer's & Dementia. 11: P299-P299. DOI: 10.1016/J.Jalz.2015.07.414  0.716
2014 Ren RJ, Dammer EB, Wang G, Seyfried NT, Levey AI. Proteomics of protein post-translational modifications implicated in neurodegeneration. Translational Neurodegeneration. 3: 23. PMID 25671099 DOI: 10.1186/2047-9158-3-23  0.713
2014 Hales CM, Seyfried NT, Dammer EB, Duong D, Yi H, Gearing M, Troncoso JC, Mufson EJ, Thambisetty M, Levey AI, Lah JJ. U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21. Molecular Neurodegeneration. 9: 15. PMID 24773620 DOI: 10.1186/1750-1326-9-15  0.714
2014 Hales CM, Dammer EB, Diner I, Yi H, Seyfried NT, Gearing M, Glass JD, Montine TJ, Levey AI, Lah JJ. Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 24: 344-51. PMID 24571648 DOI: 10.1111/Bpa.12133  0.73
2013 Hales CM, Rees H, Seyfried NT, Dammer EB, Duong DM, Gearing M, Montine TJ, Troncoso JC, Thambisetty M, Levey AI, Lah JJ, Wingo TS. Abnormal gephyrin immunoreactivity associated with Alzheimer disease pathologic changes. Journal of Neuropathology and Experimental Neurology. 72: 1009-15. PMID 24128675 DOI: 10.1097/01.Jnen.0000435847.59828.Db  0.736
2013 Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, et al. U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 16562-7. PMID 24023061 DOI: 10.1073/Pnas.1310249110  0.798
2013 Wu F, Nicholson AD, Haile WB, Torre E, An J, Chen C, Lee AK, Duong DM, Dammer EB, Seyfried NT, Tong FC, Votaw JR, Yepes M. Tissue-type plasminogen activator mediates neuronal detection and adaptation to metabolic stress. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1761-9. PMID 23881246 DOI: 10.1038/Jcbfm.2013.124  0.755
2013 Dammer EB, Duong DM, Diner I, Gearing M, Feng Y, Lah JJ, Levey AI, Seyfried NT. Neuron enriched nuclear proteome isolated from human brain. Journal of Proteome Research. 12: 3193-206. PMID 23768213 DOI: 10.1021/Pr400246T  0.685
2013 Donovan LE, Dammer EB, Duong DM, Hanfelt JJ, Levey AI, Seyfried NT, Lah JJ. Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease. Alzheimer's Research & Therapy. 5: 32. PMID 23764030 DOI: 10.1186/Alzrt186  0.726
2013 Kallappagoudar S, Dammer EB, Duong DM, Seyfried NT, Lucchesi JC. Expression, purification and proteomic analysis of recombinant histone H4 acetylated at lysine 16. Proteomics. 13: 1687-91. PMID 23554095 DOI: 10.1002/Pmic.201300025  0.623
2013 Willmund F, del Alamo M, Pechmann S, Chen T, Albanèse V, Dammer EB, Peng J, Frydman J. The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell. 152: 196-209. PMID 23332755 DOI: 10.1016/J.Cell.2012.12.001  0.548
2013 Li D, Dammer EB, Lucki NC, Sewer MB. cAMP-stimulated phosphorylation of diaphanous 1 regulates protein stability and interaction with binding partners in adrenocortical cells. Molecular Biology of the Cell. 24: 848-57. PMID 23325789 DOI: 10.1091/Mbc.E12-08-0597  0.794
2013 Higginbotham L, Donovan L, Duong D, Dammer E, Schantz A, Montine T, Lah J, Levey A, Seyfried N. O2-08-06: Analysis of the synapse-rich brain proteome reveals potential markers of asymptomatic Alzheimer's disease Alzheimer's & Dementia. 9: P331-P331. DOI: 10.1016/J.Jalz.2013.04.182  0.709
2012 Fan F, Nie S, Dammer EB, Duong DM, Pan D, Ping L, Zhai L, Wu J, Hong X, Qin L, Xu P, Zhang YH. Protein profiling of active cysteine cathepsins in living cells using an activity-based probe containing a cell-penetrating peptide. Journal of Proteome Research. 11: 5763-72. PMID 23082807 DOI: 10.1021/Pr300575U  0.323
2012 Wu F, Wu J, Nicholson AD, Echeverry R, Haile WB, Catano M, An J, Lee AK, Duong D, Dammer EB, Seyfried NT, Tong FC, Votaw JR, Medcalf RL, Yepes M. Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9848-58. PMID 22815500 DOI: 10.1523/Jneurosci.1241-12.2012  0.752
2012 Dammer EB, Fallini C, Gozal YM, Duong DM, Rossoll W, Xu P, Lah JJ, Levey AI, Peng J, Bassell GJ, Seyfried NT. Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination. Plos One. 7: e38658. PMID 22761693 DOI: 10.1371/Journal.Pone.0038658  0.764
2012 Herskowitz JH, Gozal YM, Duong DM, Dammer EB, Gearing M, Ye K, Lah JJ, Peng J, Levey AI, Seyfried NT. Asparaginyl endopeptidase cleaves TDP-43 in brain. Proteomics. 12: 2455-63. PMID 22718532 DOI: 10.1002/Pmic.201200006  0.764
2012 Li D, Dammer EB, Sewer MB. Resveratrol stimulates cortisol biosynthesis by activating SIRT-dependent deacetylation of P450scc. Endocrinology. 153: 3258-68. PMID 22585829 DOI: 10.1210/En.2011-2088  0.694
2012 Donovan LE, Higginbotham L, Dammer EB, Gearing M, Rees HD, Xia Q, Duong DM, Seyfried NT, Lah JJ, Levey AI. Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease. Proteomics. Clinical Applications. 6: 201-11. PMID 22532456 DOI: 10.1002/Prca.201100068  0.752
2012 Seyfried NT, Gozal YM, Donovan LE, Herskowitz JH, Dammer EB, Xia Q, Ku L, Chang J, Duong DM, Rees HD, Cooper DS, Glass JD, Gearing M, Tansey MG, Lah JJ, et al. Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards. Journal of Proteome Research. 11: 2721-38. PMID 22416763 DOI: 10.1021/Pr2010814  0.788
2011 Gozal YM, Dammer EB, Duong DM, Cheng D, Gearing M, Rees HD, Peng J, Lah JJ, Levey AI. Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology. Frontiers in Neurology. 2: 24. PMID 21577247 DOI: 10.3389/Fneur.2011.00024  0.631
2011 Dammer EB, Na CH, Xu P, Seyfried NT, Duong DM, Cheng D, Gearing M, Rees H, Lah JJ, Levey AI, Rush J, Peng J. Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease. The Journal of Biological Chemistry. 286: 10457-65. PMID 21278249 DOI: 10.1074/Jbc.M110.149633  0.751
2011 Sephton CF, Cenik C, Kucukural A, Dammer EB, Cenik B, Han Y, Dewey CM, Roth FP, Herz J, Peng J, Moore MJ, Yu G. Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes. The Journal of Biological Chemistry. 286: 1204-15. PMID 21051541 DOI: 10.1074/Jbc.M110.190884  0.565
2010 Dammer E, Peng J. At the crossroads of ubiquitin signaling and mass spectrometry. Expert Review of Proteomics. 7: 643-5. PMID 20973637 DOI: 10.1586/Epr.10.90  0.551
2010 Seyfried NT, Gozal YM, Dammer EB, Xia Q, Duong DM, Cheng D, Lah JJ, Levey AI, Peng J. Multiplex SILAC analysis of a cellular TDP-43 proteinopathy model reveals protein inclusions associated with SUMOylation and diverse polyubiquitin chains. Molecular & Cellular Proteomics : McP. 9: 705-18. PMID 20047951 DOI: 10.1074/Mcp.M800390-Mcp200  0.778
2008 Sewer MB, Li D, Dammer EB, Jagarlapudi S, Lucki N. Multiple Signaling Pathways Coordinate CYP17 Gene Expression in the Human Adrenal Cortex. Acta Chimica Slovenica. 55: 53-57. PMID 20098627  0.778
2008 Dammer EB, Sewer MB. Phosphorylation of CtBP1 by cAMP-dependent protein kinase modulates induction of CYP17 by stimulating partnering of CtBP1 and 2. The Journal of Biological Chemistry. 283: 6925-34. PMID 18184656 DOI: 10.1074/Jbc.M708432200  0.713
2007 Sewer MB, Dammer EB, Jagarlapudi S. Transcriptional regulation of adrenocortical steroidogenic gene expression. Drug Metabolism Reviews. 39: 371-88. PMID 17786627 DOI: 10.1080/03602530701498828  0.677
2007 Urs AN, Dammer E, Kelly S, Wang E, Merrill AH, Sewer MB. Steroidogenic factor-1 is a sphingolipid binding protein. Molecular and Cellular Endocrinology. 265: 174-8. PMID 17196738 DOI: 10.1016/J.Mce.2006.12.016  0.688
2007 Dammer EB, Leon A, Sewer MB. Coregulator exchange and sphingosine-sensitive cooperativity of steroidogenic factor-1, general control nonderepressed 5, p54, and p160 coactivators regulate cyclic adenosine 3',5'-monophosphate-dependent cytochrome P450c17 transcription rate. Molecular Endocrinology (Baltimore, Md.). 21: 415-38. PMID 17121866 DOI: 10.1210/Me.2006-0361  0.692
2006 Urs AN, Dammer E, Sewer MB. Sphingosine regulates the transcription of CYP17 by binding to steroidogenic factor-1. Endocrinology. 147: 5249-58. PMID 16887917 DOI: 10.1210/En.2006-0355  0.68
2006 Ping L, Duong D, Dammer EB, Gearing M, Lah JJ, Levey AI, Seyfried NT. P2-217: INTEGRATED PROTEOMICS AND PHOSPHOPROTEOMICS REVEAL NETWORKS LINKED TO ALZHEIMER'S DISEASE RISK Alzheimer's & Dementia. 14: P752-P752. DOI: 10.1016/J.Jalz.2018.06.905  0.697
2006 Bishof IJ, Dammer EB, Duong D, Gearing M, Lah JJ, Levey AI, Seyfried NT. O2-02-05: RNA-BINDING PROTEINS WITH MIXED CHARGE DOMAINS SELF-ASSEMBLE AND AGGREGATE IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P612-P612. DOI: 10.1016/J.Jalz.2018.06.2649  0.792
2006 Raza SA, Gao T, Dammer EB, Xiao H, Lah JJ, Seyfried NT, Levey AI, Rangaraju S. O2-01-01: A TRANSCRIPTOMIC LANDSCAPE OF MICROGLIAL ACTIVATION IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P608-P608. DOI: 10.1016/J.Jalz.2018.06.2639  0.684
2006 Abreha M, Dammer EB, Ping L, Duong D, Lah JJ, Levey AI, Seyfried NT. P3-191: COMPREHENSIVE MAPPING OF ALZHEIMER'S DISEASE BRAIN UBIQUITYLOME Alzheimer's & Dementia. 14: P1140-P1140. DOI: 10.1016/J.Jalz.2018.06.1549  0.693
Low-probability matches (unlikely to be authored by this person)
2020 Frank F, Kavousi N, Bountali A, Dammer EB, Mourtada-Maarabouni M, Ortlund EA. The lncRNA Growth Arrest Specific 5 Regulates Cell Survival via Distinct Structural Modules with Independent Functions. Cell Reports. 32: 107933. PMID 32697996 DOI: 10.1016/J.Celrep.2020.107933  0.299
2019 Li Y, Dammer EB, Gao Y, Lan Q, Villamil MA, Duong DM, Zhang C, Ping L, Lauinger L, Flick K, Xu Z, Wei W, Xing X, Chang L, Jin J, et al. Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation. Molecular Cell. PMID 31444107 DOI: 10.1016/J.Molcel.2019.07.001  0.293
2021 Hu YB, Zhang YF, Ren RJ, Dammer EB, Xie XY, Chen SW, Huang Q, Huang WY, Zhang R, Chen HZ, Wang H, Wang G. microRNA-425 loss mediates amyloid plaque microenvironment heterogeneity and promotes neurodegenerative pathologies. Aging Cell. e13454. PMID 34510683 DOI: 10.1111/acel.13454  0.292
2013 Ping L, Zhang H, Zhai L, Dammer EB, Duong DM, Li N, Yan Z, Wu J, Xu P. Quantitative proteomics reveals significant changes in cell shape and an energy shift after IPTG induction via an optimized SILAC approach for Escherichia coli. Journal of Proteome Research. 12: 5978-88. PMID 24224529 DOI: 10.1021/Pr400775W  0.287
2017 Vest KE, Phillips BL, Banerjee A, Apponi LH, Dammer EB, Xu W, Zheng D, Yu J, Tian B, Pavlath GK, Corbett AH. Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology. Human Molecular Genetics. PMID 28575395 DOI: 10.1093/Hmg/Ddx206  0.28
2021 Ren RJ, Huang Q, Xu G, Gu K, Dammer EB, Wang CF, Xie XY, Chen W, Shao ZY, Chen SD, Wang G. Association between Alzheimer's disease and risk of cancer: A retrospective cohort study in Shanghai, China. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34482613 DOI: 10.1002/alz.12436  0.249
2021 Gao Y, Ping L, Duong D, Zhang C, Dammer EB, Li Y, Chen P, Chang L, Gao H, Wu J, Xu P. Mass-Spectrometry-Based Near-Complete Draft of the Proteome. Journal of Proteome Research. PMID 33443437 DOI: 10.1021/acs.jproteome.0c00721  0.248
2022 Wang HL, Tang R, Ren RJ, Dammer EB, Guo QH, Peng GP, Cui HL, Zhang YM, Wang JT, Xie XY, Huang Q, Li JP, Yan FH, Chen SD, He NY, et al. Speech silence character as a diagnostic biomarker of early cognitive decline and its functional mechanism: a multicenter cross-sectional cohort study. Bmc Medicine. 20: 380. PMID 36336678 DOI: 10.1186/s12916-022-02584-x  0.247
2015 Xu J, Wang LL, Dammer EB, Li CB, Xu G, Chen SD, Wang G. Melatonin for Sleep Disorders and Cognition in Dementia: A Meta-Analysis of Randomized Controlled Trials. American Journal of Alzheimer's Disease and Other Dementias. PMID 25614508 DOI: 10.1177/1533317514568005  0.242
2021 Xie XY, Zhao QH, Huang Q, Dammer E, Chen SD, Ren RJ, Wang G. Genetic profiles of familial late-onset Alzheimer's disease in China: The Shanghai FLOAD study. Genes & Diseases. 9: 1639-1649. PMID 36157508 DOI: 10.1016/j.gendis.2021.05.001  0.216
2020 Yang K, Wei M, Yang Z, Fu Z, Xu R, Cheng C, Chen X, Chen S, Dammer E, Le W. Activation of dopamine receptor D1 inhibits glioblastoma tumorigenicity by regulating autophagic activity. Cellular Oncology (Dordrecht). PMID 32761562 DOI: 10.1007/S13402-020-00550-4  0.214
2023 McKinney LP, Singh R, Jordan IK, Varambally S, Dammer EB, Lillard JW. Transcriptome Analysis Identifies Tumor Immune Microenvironment Signaling Networks Supporting Metastatic Castration-Resistant Prostate Cancer. Onco. 3: 81-95. PMID 38435029 DOI: 10.3390/onco3020007  0.165
2022 Huang Q, Zhang YF, Li LJ, Dammer EB, Hu YB, Xie XY, Tang R, Li JP, Wang JT, Che XQ, Wang G, Ren RJ. Adult-Onset Neuronal Ceroid Lipofuscinosis With a Novel Mutation Exhibits Aberrant Protein Palmitoylation. Frontiers in Aging Neuroscience. 14: 829573. PMID 35462699 DOI: 10.3389/fnagi.2022.829573  0.136
2024 Kumar P, Goettemoeller AM, Espinosa-Garcia C, Tobin BR, Tfaily A, Nelson RS, Natu A, Dammer EB, Santiago JV, Malepati S, Cheng L, Xiao H, Duong DD, Seyfried NT, Wood LB, et al. Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology. Nature Communications. 15: 2823. PMID 38561349 DOI: 10.1038/s41467-024-47028-7  0.12
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