| Year |
Citation |
Score |
| 2020 |
Morgan ET, Skubic C, Lee CM, Cokan KB, Rozman D. Regulation of cytochrome P450 enzyme activity and expression by nitric oxide in the context of inflammatory disease. Drug Metabolism Reviews. 1-17. PMID 32898444 DOI: 10.1080/03602532.2020.1817061 |
0.428 |
|
| 2020 |
Cerrone J, Lee CM, Mi T, Morgan ET. Nitric Oxide Mediated Degradation of CYP2A6 via the Ubiquitin-Proteasome Pathway in Human Hepatoma Cells. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32350062 DOI: 10.1124/dmd.119.089961 |
0.311 |
|
| 2018 |
Park JW, Lee CM, Cheng JS, Morgan ET. Posttranslational regulation of CYP2J2 by nitric oxide. Free Radical Biology & Medicine. PMID 29715548 DOI: 10.1016/j.freeradbiomed.2018.04.576 |
0.353 |
|
| 2017 |
Park JW, Byrd A, Lee CM, Morgan ET. Nitric oxide stimulates cellular degradation of human CYP51A1, the highly conserved lanosterol 14α-demethylase. The Biochemical Journal. PMID 28830911 DOI: 10.1042/BCJ20170459 |
0.342 |
|
| 2017 |
Lee CM, Tripathi S, Morgan ET. Nitric oxide-regulated proteolysis of human CYP2B6 via the ubiquitin-proteasome system. Free Radical Biology & Medicine. PMID 28427998 DOI: 10.1016/j.freeradbiomed.2017.04.015 |
0.309 |
|
| 2014 |
Nyagode BA, Jahangardi R, Merrell MD, Tansey MG, Morgan ET. Selective effects of a therapeutic protein targeting tumor necrosis factor-alpha on cytochrome P450 regulation during infectious colitis: Implications for disease-dependent drug-drug interactions. Pharmacology Research & Perspectives. 2: e00027. PMID 24707356 DOI: 10.1002/Prp2.27 |
0.372 |
|
| 2014 |
Nyagode BA, Williams IR, Morgan ET. Altered inflammatory responses to Citrobacter rodentium infection, but not bacterial lipopolysaccharide, in mice lacking the Cyp4a10 or Cyp4a14 genes. Inflammation. 37: 893-907. PMID 24413902 DOI: 10.1007/s10753-013-9809-6 |
0.384 |
|
| 2014 |
Merrell MD, Nyagode BA, Clarke JD, Cherrington NJ, Morgan ET. Selective and cytokine-dependent regulation of hepatic transporters and bile acid homeostasis during infectious colitis in mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 596-602. PMID 24378326 DOI: 10.1124/Dmd.113.055525 |
0.326 |
|
| 2014 |
Mimche SM, Nyagode BA, Merrell MD, Lee CM, Prasanphanich NS, Cummings RD, Morgan ET. Hepatic cytochrome P450s, phase II enzymes and nuclear receptors are downregulated in a Th2 environment during Schistosoma mansoni infection. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 134-40. PMID 24163175 DOI: 10.1124/Dmd.113.054957 |
0.399 |
|
| 2014 |
Lee CM, Lee BS, Arnold SL, Isoherranen N, Morgan ET. Nitric oxide and interleukin-1β stimulate the proteasome-independent degradation of the retinoic acid hydroxylase CYP2C22 in primary rat hepatocytes. The Journal of Pharmacology and Experimental Therapeutics. 348: 141-52. PMID 24144795 DOI: 10.1124/Jpet.113.209841 |
0.34 |
|
| 2012 |
Nyagode BA, Watkins WJ, Kinloch RD, Morgan ET. Selective modulation of hepatic cytochrome P450 and flavin monooxygenase 3 expression during citrobacter rodentium infection in severe combined immune-deficient mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 1894-9. PMID 22745333 DOI: 10.1124/Dmd.112.046557 |
0.365 |
|
| 2011 |
Kinloch RD, Lee CM, van Rooijen N, Morgan ET. Selective role for tumor necrosis factor-α, but not interleukin-1 or Kupffer cells, in down-regulation of CYP3A11 and CYP3A25 in livers of mice infected with a noninvasive intestinal pathogen. Biochemical Pharmacology. 82: 312-21. PMID 21570957 DOI: 10.1016/J.Bcp.2011.04.016 |
0.391 |
|
| 2010 |
Nyagode BA, Lee CM, Morgan ET. Modulation of hepatic cytochrome P450s by Citrobacter rodentium infection in interleukin-6- and interferon-{gamma}-null mice. The Journal of Pharmacology and Experimental Therapeutics. 335: 480-8. PMID 20719939 DOI: 10.1124/jpet.110.171488 |
0.372 |
|
| 2009 |
Lee CM, Pohl J, Morgan ET. Dual mechanisms of CYP3A protein regulation by proinflammatory cytokine stimulation in primary hepatocyte cultures. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 865-72. PMID 19171675 DOI: 10.1124/dmd.108.026187 |
0.377 |
|
| 2009 |
Zhang J, Chaluvadi MR, Reddy R, Motika MS, Richardson TA, Cashman JR, Morgan ET. Hepatic flavin-containing monooxygenase gene regulation in different mouse inflammation models. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 462-8. PMID 19088265 DOI: 10.1124/dmd.108.025338 |
0.512 |
|
| 2009 |
Chaluvadi MR, Nyagode BA, Kinloch RD, Morgan ET. TLR4-dependent and -independent regulation of hepatic cytochrome P450 in mice with chemically induced inflammatory bowel disease. Biochemical Pharmacology. 77: 464-71. PMID 19027721 DOI: 10.1016/J.Bcp.2008.10.029 |
0.591 |
|
| 2009 |
Chaluvadi MR, Kinloch RD, Nyagode BA, Richardson TA, Raynor MJ, Sherman M, Antonovic L, Strobel HW, Dillehay DL, Morgan ET. Regulation of hepatic cytochrome P450 expression in mice with intestinal or systemic infections of citrobacter rodentium. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 366-74. PMID 18971315 DOI: 10.1124/Dmd.108.024240 |
0.4 |
|
| 2008 |
Chen C, Shah YM, Morimura K, Krausz KW, Miyazaki M, Richardson TA, Morgan ET, Ntambi JM, Idle JR, Gonzalez FJ. Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis. Cell Metabolism. 7: 135-47. PMID 18249173 DOI: 10.1016/J.Cmet.2007.12.003 |
0.392 |
|
| 2008 |
Aitken AE, Lee CM, Morgan ET. Roles of nitric oxide in inflammatory downregulation of human cytochromes P450. Free Radical Biology & Medicine. 44: 1161-8. PMID 18206661 DOI: 10.1016/j.freeradbiomed.2007.12.010 |
0.454 |
|
| 2008 |
Lee CM, Kim BY, Li L, Morgan ET. Nitric oxide-dependent proteasomal degradation of cytochrome P450 2B proteins. The Journal of Biological Chemistry. 283: 889-98. PMID 17993647 DOI: 10.1074/jbc.M708821200 |
0.406 |
|
| 2007 |
Aitken AE, Morgan ET. Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1687-93. PMID 17576808 DOI: 10.1124/dmd.107.015511 |
0.41 |
|
| 2007 |
Kalsotra A, Anakk S, Brommer CL, Kikuta Y, Morgan ET, Strobel HW. Catalytic characterization and cytokine mediated regulation of cytochrome P450 4Fs in rat hepatocytes. Archives of Biochemistry and Biophysics. 461: 104-12. PMID 17418803 DOI: 10.1016/J.Abb.2007.02.027 |
0.358 |
|
| 2006 |
Aitken AE, Richardson TA, Morgan ET. Regulation of drug-metabolizing enzymes and transporters in inflammation. Annual Review of Pharmacology and Toxicology. 46: 123-49. PMID 16402901 DOI: 10.1146/annurev.pharmtox.46.120604.141059 |
0.327 |
|
| 2006 |
Richardson TA, Sherman M, Antonovic L, Kardar SS, Strobel HW, Kalman D, Morgan ET. Hepatic and renal cytochrome p450 gene regulation during citrobacter rodentium infection in wild-type and toll-like receptor 4 mutant mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 354-60. PMID 16339354 DOI: 10.1124/Dmd.105.007393 |
0.418 |
|
| 2006 |
Richardson TA, Sherman M, Kalman D, Morgan ET. Expression of UDP-glucuronosyltransferase isoform mRNAs during inflammation and infection in mouse liver and kidney. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 351-3. PMID 16339353 DOI: 10.1124/Dmd.105.007435 |
0.499 |
|
| 2005 |
Richardson TA, Morgan ET. Hepatic cytochrome P450 gene regulation during endotoxin-induced inflammation in nuclear receptor knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 314: 703-9. PMID 15860574 DOI: 10.1124/jpet.105.085456 |
0.521 |
|
| 2004 |
Riddick DS, Lee C, Bhathena A, Timsit YE, Cheng PY, Morgan ET, Prough RA, Ripp SL, Miller KK, Jahan A, Chiang JY. Transcriptional suppression of cytochrome P450 genes by endogenous and exogenous chemicals. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 367-75. PMID 15039287 DOI: 10.1124/Dmd.32.4.367 |
0.339 |
|
| 2003 |
Kalsotra A, Cui X, Antonovic L, Robida AM, Morgan ET, Strobel HW. Inflammatory prompts produce isoform-specific changes in the expression of leukotriene B(4) omega-hydroxylases in rat liver and kidney. Febs Letters. 555: 236-42. PMID 14644421 DOI: 10.1016/S0014-5793(03)01240-7 |
0.526 |
|
| 2003 |
Cheng PY, Wang M, Morgan ET. Rapid transcriptional suppression of rat cytochrome P450 genes by endotoxin treatment and its inhibition by curcumin. The Journal of Pharmacology and Experimental Therapeutics. 307: 1205-12. PMID 14557382 DOI: 10.1124/jpet.103.057174 |
0.501 |
|
| 2002 |
Morgan ET, Li-Masters T, Cheng PY. Mechanisms of cytochrome P450 regulation by inflammatory mediators. Toxicology. 181: 207-10. PMID 12505312 DOI: 10.1016/S0300-483X(02)00283-4 |
0.766 |
|
| 2002 |
Li-Masters T, Morgan ET. Down-regulation of phenobarbital-induced cytochrome P4502B mRNAs and proteins by endotoxin in mice: independence from nitric oxide production by inducible nitric oxide synthase. Biochemical Pharmacology. 64: 1703-11. PMID 12445859 DOI: 10.1016/S0006-2952(02)01423-5 |
0.758 |
|
| 2001 |
Cheng PY, Morgan ET. Hepatic cytochrome P450 regulation in disease states. Current Drug Metabolism. 2: 165-83. PMID 11469724 DOI: 10.2174/1389200013338676 |
0.416 |
|
| 2001 |
Ferrari L, Peng N, Halpert JR, Morgan ET. Role of nitric oxide in down-regulation of CYP2B1 protein, but not RNA, in primary cultures of rat hepatocytes. Molecular Pharmacology. 60: 209-16. PMID 11408616 DOI: 10.1124/MOL.60.1.209 |
0.517 |
|
| 2001 |
Iber H, Li-Masters T, Chen Q, Yu S, Morgan ET. Regulation of hepatic cytochrome P450 2C11 via cAMP: implications for down-regulation in diabetes, fasting, and inflammation. The Journal of Pharmacology and Experimental Therapeutics. 297: 174-80. PMID 11259542 |
0.734 |
|
| 2001 |
Li-Masters T, Morgan ET. Effects of bacterial lipopolysaccharide on phenobarbital-induced CYP2B expression in mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 29: 252-7. PMID 11181491 |
0.756 |
|
| 2001 |
Mitchell SR, Sewer MB, Kardar SS, Morgan ET. Characterization of CYP4A induction in rat liver by inflammatory stimuli: Dependence on sex, strain, and inflammation-evoked hypophagia Drug Metabolism and Disposition. 29: 17-22. PMID 11124224 |
0.722 |
|
| 2000 |
Iber H, Chen Q, Cheng PY, Morgan ET. Suppression of CYP2C11 gene transcription by interleukin-1 mediated by NF-kappaB binding at the transcription start site. Archives of Biochemistry and Biophysics. 377: 187-94. PMID 10775459 DOI: 10.1006/ABBI.2000.1772 |
0.364 |
|
| 1999 |
Merrill AH, Nikolova-Karakashian M, Schmelz EM, Morgan ET, Stewart J. Regulation of cytochrome P450 expression by sphingolipids Chemistry and Physics of Lipids. 102: 131-139. PMID 11001567 DOI: 10.1016/S0009-3084(99)00081-X |
0.322 |
|
| 1999 |
Merrill AH, Morgan ET, Nikolova-Karakashian M, Stewart J. Sphingomyelin hydrolysis and regulation of the expression of the gene for cytochrome P450 Biochemical Society Transactions. 27: 383-387. PMID 10917607 DOI: 10.1042/Bst0270383 |
0.366 |
|
| 1999 |
Barclay TB, Peters JM, Sewer MB, Ferrari L, Gonzalez FJ, Morgan ET. Modulation of cytochrome P-450 gene expression in endotoxemic mice is tissue specific and peroxisome proliferator-activated receptor-alpha dependent. The Journal of Pharmacology and Experimental Therapeutics. 290: 1250-7. PMID 10454501 |
0.773 |
|
| 1999 |
Iber H, Sewer MB, Barclay TB, Mitchell SR, Tong LI, Morgan ET. Modulation of drug metabolism in infectious and inflammatory diseases Drug Metabolism Reviews. 31: 29-41. PMID 10065364 DOI: 10.1081/DMR-100101906 |
0.71 |
|
| 1999 |
Merrill AH, Morgan ET. Sphingomyelin metabolism and regulation of cytochrome P450 gene expression Biochemical Society Transactions. 27: A62-A62. DOI: 10.1042/Bst027A062B |
0.331 |
|
| 1998 |
Morgan ET, Sewer MB, Iber H, Gonzalez FJ, Lee YH, Tukey RH, Okino S, Vu T, Chen YH, Sidhu JS, Omiecinski CJ. Physiological and pathophysiological regulation of cytochrome P450. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 26: 1232-40. PMID 9860933 |
0.691 |
|
| 1998 |
Sewer MB, Morgan ET. Down-regulation of the expression of three major rat liver cytochrome P450S by endotoxin in vivo occurs independently of nitric oxide production. The Journal of Pharmacology and Experimental Therapeutics. 287: 352-8. PMID 9765356 |
0.791 |
|
| 1998 |
Sewer MB, Barclay TB, Morgan ET. Down-regulation of cytochrome P450 mRNAs and proteins in mice lacking a functional NOS2 gene. Molecular Pharmacology. 54: 273-9. PMID 9687568 |
0.755 |
|
| 1998 |
Morgan ET. Regulation of cytochromes P450 during inflammation and infection. Drug Metabolism Reviews. 29: 1129-88. PMID 9421688 DOI: 10.3109/03602539709002246 |
0.446 |
|
| 1998 |
Ferrari L, Morgan ET. No is not involved in LPS repression of CYP2B1 MRNA in primary rat hepatocytes Toxicology Letters. 95: 111-112. DOI: 10.1016/s0378-4274(98)80441-4 |
0.454 |
|
| 1997 |
Sewer MB, Morgan ET. Nitric oxide-independent suppression of P450 2C11 expression by interleukin-1beta and endotoxin in primary rat hepatocytes. Biochemical Pharmacology. 54: 729-37. PMID 9310350 |
0.74 |
|
| 1997 |
Sewer MB, Koop DR, Morgan ET. Differential inductive and suppressive effects of endotoxin and particulate irritants on hepatic and renal cytochrome P-450 expression. The Journal of Pharmacology and Experimental Therapeutics. 280: 1445-54. PMID 9067334 |
0.754 |
|
| 1996 |
Sewer MB, Koop DR, Morgan ET. Endotoxemia in rats is associated with induction of the P4504A subfamily and suppression of several other forms of cytochrome P450. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 24: 401-7. PMID 8801054 |
0.764 |
|
| 1996 |
Morgan ET, Nikolova-Karakashian M, Chen JQ, Merrill AH. Sphingolipid-dependent signaling in regulation of cytochrome P450 expression Methods in Enzymology. 272: 381-388. PMID 8791797 DOI: 10.1016/S0076-6879(96)72043-8 |
0.423 |
|
| 1995 |
Chen J, Nikolova-Karakashian M, Merrill AH, Morgan ET. Regulation of cytochrome P450 2C11 (CYP2C11) gene expression by interleukin-1, sphingomyelin hydrolysis, and ceramides in rat hepatocytes Journal of Biological Chemistry. 270: 25233-25238. PMID 7559661 DOI: 10.1074/Jbc.270.42.25233 |
0.396 |
|
| 1994 |
Morgan ET, Thomas KB, Swanson R, Vales T, Hwang J, Wright K. Selective suppression of cytochrome P-450 gene expression by interleukins 1 and 6 in rat liver Bba - Gene Structure and Expression. 1219: 475-483. PMID 7918645 DOI: 10.1016/0167-4781(94)90074-4 |
0.346 |
|
| 1993 |
Morgan ET. Down-regulation of multiple cytochrome P450 gene products by inflammatory mediators in vivo. Independence from the hypothalamo-pituitary axis. Biochemical Pharmacology. 45: 415-9. PMID 8435092 DOI: 10.1016/0006-2952(93)90078-B |
0.506 |
|
| 1991 |
Morgan ET. Suppression of P450IIC12 gene expression and elevation of actin messenger ribonucleic acid levels in the livers of female rats after injection of the interferon inducer poly rI.poly rC. Biochemical Pharmacology. 42: 51-7. PMID 2069598 DOI: 10.1016/0006-2952(91)90680-4 |
0.464 |
|
| 1990 |
Wright K, Morgan ET. Transcriptional and post-transcriptional suppression of P450IIC11 and P450IIC12 by inflammation. Febs Letters. 271: 59-61. PMID 2226815 DOI: 10.1016/0014-5793(90)80371-O |
0.399 |
|
| 1988 |
Ström A, Mode A, Zaphiropoulos P, Nilsson A, Morgan E, Gustafsson J. Cloning and pretranslational hormonal regulation of testosterone 16α-hydroxylase (P-45016α) in male rat liver European Journal of Endocrinology. 118: 314-320. PMID 2455430 DOI: 10.1530/Acta.0.1180314 |
0.417 |
|
| 1987 |
Ström A, Mode A, Morgan E, Gustafsson J. Pretranslational hormonal control of male-specific cytochrome P-45016α in rat liver Biochemical Society Transactions. 15: 575-576. PMID 3678577 DOI: 10.1042/Bst0150575 |
0.392 |
|
| 1987 |
MacGeoch C, Morgan ET, Cordell B, Gustafsson JA. Growth hormone regulates expression of rat liver cytochrome P-450 15 beta at a pretranslational level. Biochemical and Biophysical Research Communications. 143: 782-8. PMID 3494447 DOI: 10.1016/0006-291X(87)91422-7 |
0.365 |
|
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