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Zhixun Dou, Ph.D. - Publications

Affiliations: 
2012 Molecular and Cellular Biology Stony Brook University, Stony Brook, NY, United States 
Area:
Cell Biology, Molecular Biology, Medicine and Surgery
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Miller KN, Li B, Pierce-Hoffman HR, Patel S, Lei X, Rajesh A, Teneche MG, Havas AP, Gandhi A, Macip CC, Lyu J, Victorelli SG, Woo SH, Lagnado AB, LaPorta MA, ... ... Dou Z, et al. p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells. Nature Communications. 16: 2229. PMID 40044657 DOI: 10.1038/s41467-025-57229-3  0.303
2023 Miller KN, Li B, Pierce-Hoffman HR, Lei X, Havas AP, Patel S, Macip CC, Victorelli SG, Woo SH, Lagnado AB, Liu T, Dasgupta N, Lyu J, Altman Y, Porritt RA, ... ... Dou Z, et al. A mitochondria-regulated p53-CCF circuit integrates genome integrity with inflammation. Biorxiv : the Preprint Server For Biology. PMID 38045344 DOI: 10.1101/2023.11.20.567963  0.324
2020 Wang L, Xu C, Johansen T, Berger SL, Dou Z. SIRT1 - a new mammalian substrate of nuclear autophagy. Autophagy. PMID 33292048 DOI: 10.1080/15548627.2020.1860541  0.33
2020 Xu C, Wang L, Fozouni P, Evjen G, Chandra V, Jiang J, Lu C, Nicastri M, Bretz C, Winkler JD, Amaravadi R, Garcia BA, Adams PD, Ott M, Tong W, ... ... Dou Z, et al. SIRT1 is downregulated by autophagy in senescence and ageing. Nature Cell Biology. PMID 32989246 DOI: 10.1038/s41556-020-00579-5  0.363
2020 Vizioli MG, Liu T, Miller KN, Robertson NA, Gilroy K, Lagnado AB, Perez-Garcia A, Kiourtis C, Dasgupta N, Lei X, Kruger PJ, Nixon C, Clark W, Jurk D, Bird TG, ... ... Dou Z, et al. Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence. Genes & Development. PMID 32001510 DOI: 10.1101/Gad.331272.119  0.42
2019 Sen P, Lan Y, Li CY, Sidoli S, Donahue G, Dou Z, Frederick B, Chen Q, Luense LJ, Garcia BA, Dang W, Johnson FB, Adams PD, Schultz DC, Berger SL. Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence. Molecular Cell. PMID 30773298 DOI: 10.1016/J.Molcel.2019.01.021  0.414
2017 Wangensteen KJ, Wang YJ, Dou Z, Wang AW, Mosleh-Shirazi E, Horlbeck MA, Gilbert LA, Weissman JS, Berger SL, Kaestner KH. Combinatorial genetics in liver repopulation and carcinogenesis with a novel in vivo CRISPR activation platform. Hepatology (Baltimore, Md.). PMID 29091290 DOI: 10.1002/Hep.29626  0.332
2017 Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, et al. Cytoplasmic chromatin triggers inflammation in senescence and cancer. Nature. PMID 28976970 DOI: 10.1038/Nature24050  0.377
2016 Jaber N, Mohd-Naim N, Wang Z, DeLeon JL, Kim S, Zhong H, Sheshadri N, Dou Z, Edinger AL, Du G, Braga VM, Zong WX. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase activating protein Armus. Journal of Cell Science. PMID 27793976 DOI: 10.1242/Jcs.192260  0.689
2016 Zhu J, Dou Z, Sammons MA, Levine AJ, Berger SL. Lysine methylation represses p53 activity in teratocarcinoma cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27535933 DOI: 10.1073/Pnas.1610387113  0.44
2016 Pan JA, Sun Y, Jiang YP, Bott AJ, Jaber N, Dou Z, Yang B, Chen JS, Catanzaro JM, Du C, Ding WX, Diaz-Meco MT, Moscat J, Ozato K, Lin RZ, et al. TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis. Molecular Cell. 62: 149-151. PMID 27058791 DOI: 10.1016/j.molcel.2016.03.015  0.704
2016 Pan JA, Sun Y, Jiang YP, Bott AJ, Jaber N, Dou Z, Yang B, Chen JS, Catanzaro JM, Du C, Ding WX, Diaz-Meco MT, Moscat J, Ozato K, Lin RZ, et al. TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis. Molecular Cell. 61: 720-733. PMID 26942676 DOI: 10.1016/J.Molcel.2016.02.007  0.703
2016 Capell BC, Drake AM, Zhu J, Shah PP, Dou Z, Dorsey J, Simola DF, Donahue G, Sammons M, Rai TS, Natale C, Ridky TW, Adams PD, Berger SL. MLL1 is essential for the senescence-associated secretory phenotype. Genes & Development. 30: 321-36. PMID 26833731 DOI: 10.1101/Gad.271882.115  0.359
2015 Dou Z, Ivanov A, Adams PD, Berger SL. Mammalian autophagy degrades nuclear constituents in response to tumorigenic stress. Autophagy. 0. PMID 26654219 DOI: 10.1080/15548627.2015.1127465  0.485
2015 Dou Z, Xu C, Donahue G, Shimi T, Pan JA, Zhu J, Ivanov A, Capell BC, Drake AM, Shah PP, Catanzaro JM, Daniel Ricketts M, Lamark T, Adam SA, Marmorstein R, et al. Autophagy mediates degradation of nuclear lamina. Nature. 527: 105-9. PMID 26524528 DOI: 10.1038/Nature15548  0.735
2015 Zhu J, Sammons MA, Donahue G, Dou Z, Vedadi M, Getlik M, Barsyte-Lovejoy D, Al-awar R, Katona BW, Shilatifard A, Huang J, Hua X, Arrowsmith CH, Berger SL. Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth. Nature. 525: 206-11. PMID 26331536 DOI: 10.1038/Nature15251  0.417
2014 McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX, Yue Z. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex. Plos Genetics. 10: e1004626. PMID 25275521 DOI: 10.1371/Journal.Pgen.1004626  0.7
2014 Zhou Z, Jia X, Xue Q, Dou Z, Ma Y, Zhao Z, Jiang Z, He B, Jin Q, Wang J. TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response. Proceedings of the National Academy of Sciences of the United States of America. 111: E245-54. PMID 24379373 DOI: 10.1073/Pnas.1316941111  0.355
2013 Dou Z, Pan JA, Dbouk HA, Ballou LM, DeLeon JL, Fan Y, Chen JS, Liang Z, Li G, Backer JM, Lin RZ, Zong WX. Class IA PI3K p110β subunit promotes autophagy through Rab5 small GTPase in response to growth factor limitation. Molecular Cell. 50: 29-42. PMID 23434372 DOI: 10.1016/J.Molcel.2013.01.022  0.642
2012 Jaber N, Dou Z, Lin RZ, Zhang J, Zong WX. Mammalian PIK3C3/VPS34: the key to autophagic processing in liver and heart. Autophagy. 8: 707-8. PMID 22498475 DOI: 10.4161/Auto.19627  0.647
2012 Jaber N, Dou Z, Chen JS, Catanzaro J, Jiang YP, Ballou LM, Selinger E, Ouyang X, Lin RZ, Zhang J, Zong WX. Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function. Proceedings of the National Academy of Sciences of the United States of America. 109: 2003-8. PMID 22308354 DOI: 10.1073/Pnas.1112848109  0.726
2011 Pan JA, Ullman E, Dou Z, Zong WX. Inhibition of protein degradation induces apoptosis through a microtubule-associated protein 1 light chain 3-mediated activation of caspase-8 at intracellular membranes. Molecular and Cellular Biology. 31: 3158-70. PMID 21628531 DOI: 10.1128/Mcb.05460-11  0.754
2011 Dou Z, Pan JA, Lin RZ, Zong WX. The beta identity of class I PtdIns3K: A positive role of p110β in autophagy revealed Autophagy. 7: 246-247. PMID 21160279 DOI: 10.4161/Auto.7.2.14346  0.669
2010 Dou Z, Chattopadhyay M, Pan JA, Guerriero JL, Jiang YP, Ballou LM, Yue Z, Lin RZ, Zong WX. The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy. The Journal of Cell Biology. 191: 827-43. PMID 21059846 DOI: 10.1083/Jcb.201006056  0.763
2007 Zhou Z, Yin J, Dou Z, Tang J, Zhang C, Cao Y. The calponin homology domain of Vav1 associates with calmodulin and is prerequisite to T cell antigen receptor-induced calcium release in Jurkat T lymphocytes. The Journal of Biological Chemistry. 282: 23737-44. PMID 17550897 DOI: 10.1074/Jbc.M702975200  0.303
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