Suzanne L. Iverson, Ph.D. - Publications

2002 University of Toronto, Toronto, ON, Canada 
Toxicology, Pharmacology, Pathology

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Smith DA, Iverson SL. Introduction: History of metabolite safety in drug development Metabolite Safety in Drug Development. 1-16. DOI: 10.1002/9781118949689.ch1  1
2016 Iverson SL, Smith DA. Metabolite Safety in Drug Development Metabolite Safety in Drug Development. 1-331. DOI: 10.1002/9781118949689  1
2015 Goodwin RJ, Nilsson A, Mackay CL, Swales JG, Johansson MK, Billger M, Andrén PE, Iverson SL. Exemplifying the Screening Power of Mass Spectrometry Imaging over Label-Based Technologies for Simultaneous Monitoring of Drug and Metabolite Distributions in Tissue Sections. Journal of Biomolecular Screening. PMID 26701101 DOI: 10.1177/1087057115623740  1
2015 Swales JG, Tucker JW, Spreadborough MJ, Iverson SL, Clench MR, Webborn PJ, Goodwin RJ. Mapping Drug Distribution in Brain Tissue Using Liquid Extraction Surface Analysis Mass Spectrometry Imaging. Analytical Chemistry. PMID 26350423 DOI: 10.1021/acs.analchem.5b02998  0.01
2014 Haglund J, Halldin MM, Brunnström A, Eklund G, Kautiainen A, Sandholm A, Iverson SL. Pragmatic approaches to determine the exposures of drug metabolites in preclinical and clinical subjects in the MIST evaluation of the clinical development phase. Chemical Research in Toxicology. 27: 601-10. PMID 24593263 DOI: 10.1021/tx400449z  1
2012 Goodwin RJ, Nilsson A, Borg D, Langridge-Smith PR, Harrison DJ, Mackay CL, Iverson SL, Andrén PE. Conductive carbon tape used for support and mounting of both whole animal and fragile heat-treated tissue sections for MALDI MS imaging and quantitation. Journal of Proteomics. 75: 4912-20. PMID 22796569 DOI: 10.1016/J.Jprot.2012.07.006  0.08
2012 Goodwin RJ, Iverson SL, Andren PE. The significance of ambient-temperature on pharmaceutical and endogenous compound abundance and distribution in tissues sections when analyzed by matrix-assisted laser desorption/ionization mass spectrometry imaging. Rapid Communications in Mass Spectrometry : Rcm. 26: 494-8. PMID 22302488 DOI: 10.1002/rcm.6125  0.08
2011 Goodwin RJ, Mackay CL, Nilsson A, Harrison DJ, Farde L, Andren PE, Iverson SL. Qualitative and quantitative MALDI imaging of the positron emission tomography ligands raclopride (a D2 dopamine antagonist) and SCH 23390 (a D1 dopamine antagonist) in rat brain tissue sections using a solvent-free dry matrix application method. Analytical Chemistry. 83: 9694-701. PMID 22077717 DOI: 10.1021/ac202630t  1
2011 Blatherwick EQ, Van Berkel GJ, Pickup K, Johansson MK, Beaudoin ME, Cole RO, Day JM, Iverson S, Wilson ID, Scrivens JH, Weston DJ. Utility of spatially-resolved atmospheric pressure surface sampling and ionization techniques as alternatives to mass spectrometric imaging (MSI) in drug metabolism. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 41: 720-34. PMID 21671748 DOI: 10.3109/00498254.2011.587550  1
2010 Iverson S, Kautiainen A, Ip J, Uetrecht JP. Effect of clozapine on neutrophil kinetics in rabbits. Chemical Research in Toxicology. 23: 1184-91. PMID 20553052 DOI: 10.1021/Tx100035K  1
2004 Iverson SL, Orrenius S. The cardiolipin-cytochrome c interaction and the mitochondrial regulation of apoptosis. Archives of Biochemistry and Biophysics. 423: 37-46. PMID 14989263  0.01
2004 Iverson SL, Enoksson M, Gogvadze V, Ott M, Orrenius S. Cardiolipin is not required for Bax-mediated cytochrome c release from yeast mitochondria. The Journal of Biological Chemistry. 279: 1100-7. PMID 14551208 DOI: 10.1074/jbc.M305020200  0.01
2002 Iverson S, Zahid N, Uetrecht JP. Predicting drug-induced agranulocytosis: characterizing neutrophil-generated metabolites of a model compound, DMP 406, and assessing the relevance of an in vitro apoptosis assay for identifying drugs that may cause agranulocytosis. Chemico-Biological Interactions. 142: 175-99. PMID 12399162 DOI: 10.1016/S0009-2797(02)00061-3  0.4
2001 Iverson SL, Uetrecht JP. Identification of a reactive metabolite of terbinafine: insights into terbinafine-induced hepatotoxicity. Chemical Research in Toxicology. 14: 175-81. PMID 11258966 DOI: 10.1021/Tx0002029  1
1997 Bolton JL, Pisha E, Shen L, Krol ES, Iverson SL, Huang Z, Van Breemen RB, Pezzuto JM. The reactivity of o-quinones which do not isomerize to quinone methides correlates with alkylcatechol-induced toxicity in human melanoma cells Chemico-Biological Interactions. 106: 133-148. PMID 9366899 DOI: 10.1016/S0009-2797(97)00066-5  1
1996 Iverson SL, Shen L, Anlar N, Bolton JL. Bioactivation of estrone and its catechol metabolites to quinoid-glutathione conjugates in rat liver microsomes Chemical Research in Toxicology. 9: 492-499. PMID 8839054 DOI: 10.1021/Tx950178C  1
1995 Iverson SL, Hu LQ, Vukomanovic V, Bolton JL. The influence of the p-alkyl substituent on the isomerization of o-quinones to p-quinone methides: Potential bioactivation mechanism for catechols Chemical Research in Toxicology. 8: 537-544. PMID 7548733 DOI: 10.1021/Tx00046A007  1
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