Benjamin G. Bitler, Ph.D. - Publications

Affiliations: 
2010 Cancer Biology University of Arizona, Tucson, AZ 
Area:
Cell Biology

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Year Citation  Score
2024 Persenaire C, Babbs B, Yamamoto TM, Nebbia M, Jordan KR, Adams S, Lambert JR, Bitler BG. VDX-111, a novel small molecule, induces necroptosis to inhibit ovarian cancer progression. Molecular Carcinogenesis. PMID 38558423 DOI: 10.1002/mc.23721  0.402
2024 Crump LS, Floyd JL, Kuo LW, Post MD, Bickerdike M, O'Neill K, Sompel K, Jordan KR, Corr BR, Marjon N, Woodruff ER, Richer JK, Bitler BG. Targeting tryptophan catabolism in ovarian cancer to attenuate macrophage infiltration and PD-L1 expression. Cancer Research Communications. 4: 822-33. PMID 38451784 DOI: 10.1158/2767-9764.CRC-23-0513  0.347
2024 Villagomez FR, Lang J, Webb P, Neville M, Woodruff ER, Bitler BG. Claudin-4 modulates autophagy via SLC1A5/LAT1 as a tolerance mechanism for genomic instability in ovarian cancer. Biorxiv : the Preprint Server For Biology. PMID 38293054 DOI: 10.1101/2024.01.18.576263  0.364
2023 Sottnik JL, Shackleford MT, Robinson SK, Villagomez FR, Bahnassy S, Oesterreich S, Hu J, Madak-Erdogan Z, Riggins RB, Corr BR, Cook LS, Treviño LS, Bitler BG, Sikora MJ. WNT4 regulates cellular metabolism via intracellular activity at the mitochondria in breast and gynecologic cancers. Cancer Research Communications. PMID 38112643 DOI: 10.1158/2767-9764.CRC-23-0275  0.328
2023 Bapat J, Yamamoto TM, Woodruff ER, Qamar L, Mikeska RG, Aird KM, Watson ZL, Brubaker LW, Bitler BG. CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR. Cancer Gene Therapy. PMID 38030811 DOI: 10.1038/s41417-023-00703-1  0.405
2023 Callaway CS, Mouchantat LM, Bitler BG, Bonetto A. Mechanisms of Ovarian Cancer-Associated Cachexia. Endocrinology. 165. PMID 37980602 DOI: 10.1210/endocr/bqad176  0.343
2023 Brubaker LW, Backos DS, Nguyen VT, Reigan P, Yamamoto TM, Woodruff ER, Iwanaga R, Wempe MF, Kumar V, Persenaire C, Watson ZL, Bitler BG. Novel chromobox 2 inhibitory peptide decreases tumor progression. Expert Opinion On Therapeutic Targets. 1-11. PMID 37243607 DOI: 10.1080/14728222.2023.2218614  0.406
2023 Corr BR, Moroney MR, Woodruff E, Watson ZL, Jordan KR, Danhorn T, Bailey C, Wolsky RJ, Bitler BG. Combination CDC-like kinase inhibition (CLK)/Dual-specificity tyrosine-regulated kinase (DYRK) and taxane therapy in -mutated endometrial cancer. Biorxiv : the Preprint Server For Biology. PMID 37066339 DOI: 10.1101/2023.04.04.535570  0.423
2022 Neville MC, Webb PG, Baumgartner HK, Bitler BG. Claudin-4 localization in epithelial ovarian cancer. Heliyon. 8: e10862. PMID 36237976 DOI: 10.1016/j.heliyon.2022.e10862  0.312
2022 Holmberg R, Robinson M, Gilbert SF, Lujano-Olazaba O, Waters JA, Kogan E, Velasquez CLR, Stevenson D, Cruz LS, Alexander LJ, Lara J, Mu EM, Camillo JR, Bitler BG, Huxford T, et al. TWEAK-Fn14-RelB signaling cascade promotes stem cell-like features that contribute to post-chemotherapy ovarian cancer relapse. Molecular Cancer Research : McR. PMID 36214671 DOI: 10.1158/1541-7786.MCR-22-0486  0.413
2022 McMellen A, Yamamoto TM, Qamar L, Sanders BE, Nguyen LL, Ortiz Chavez D, Bapat J, Berning A, Post MD, Johnson J, Behbakht K, Nurmemmedov E, Chuong EB, Bitler BG. ATF6-mediated signaling contributes to PARP Inhibitor Resistance in Ovarian Cancer. Molecular Cancer Research : McR. PMID 36149636 DOI: 10.1158/1541-7786.MCR-22-0102  0.302
2022 Liu H, Lin J, Zhou W, Moses R, Dai Z, Kossenkov AV, Drapkin R, Bitler BG, Karakashev S, Zhang R. KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer. Cancer Immunology Research. OF1-OF11. PMID 35726891 DOI: 10.1158/2326-6066.CIR-22-0088  0.313
2022 Vu T, Wrobel J, Bitler BG, Schenk EL, Jordan KR, Ghosh D. SPF: A spatial and functional data analytic approach to cell imaging data. Plos Computational Biology. 18: e1009486. PMID 35704658 DOI: 10.1371/journal.pcbi.1009486  0.304
2022 Sanders BE, Yamamoto TM, McMellen A, Woodruff ER, Berning A, Post MD, Bitler BG. Targeting DUSP activity as a treatment for high grade serous ovarian carcinoma. Molecular Cancer Therapeutics. PMID 35587258 DOI: 10.1158/1535-7163.MCT-21-0682  0.398
2022 Yamamoto TM, Webb PG, Davis DM, Baumgartner HK, Woodruff ER, Guntupalli SR, Neville M, Behbakht K, Bitler BG. Loss of Claudin-4 Reduces DNA Damage Repair and Increases Sensitivity to PARP Inhibitors. Molecular Cancer Therapeutics. 21: 647-657. PMID 35373300 DOI: 10.1158/1535-7163.MCT-21-0827  0.392
2021 Moroney MR, Woodruff E, Qamar L, Bradford AP, Wolsky R, Bitler BG, Corr BR. Inhibiting Wnt/beta-catenin in CTNNB1-mutated endometrial cancer. Molecular Carcinogenesis. PMID 34038589 DOI: 10.1002/mc.23308  0.333
2020 Jordan K, Sikora MJ, Slansky JE, Minic A, Richer JK, Moroney MR, Hu J, Wolsky RJ, Watson ZL, Yamamoto TM, Costello JC, Clauset A, Behbakht K, Kumar TR, Bitler BG. The capacity of the ovarian cancer tumor microenvironment to integrate inflammation signaling conveys a shorter disease-free interval. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32928797 DOI: 10.1158/1078-0432.Ccr-20-1762  0.454
2020 McMellen A, Woodruff ER, Corr BR, Bitler BG, Moroney MR. Wnt Signaling in Gynecologic Malignancies. International Journal of Molecular Sciences. 21. PMID 32560059 DOI: 10.3390/Ijms21124272  0.385
2020 Sawyer BT, Qamar L, Yamamoto TM, McMellen A, Watson ZL, Richer JK, Behbakht K, Schlaepfer IR, Bitler BG. Targeting fatty acid oxidation to promote anoikis and inhibit ovarian cancer progression. Molecular Cancer Research : McR. PMID 32198139 DOI: 10.1158/1541-7786.Mcr-19-1057  0.467
2020 Li J, Wang W, Zhang Y, Cieślik M, Guo J, Tan M, Green MD, Wang W, Lin H, Li W, Wei S, Zhou J, Li G, Jing X, Vatan L, ... ... Bitler B, et al. Epigenetic driver mutations in ARID1A shape cancer immune phenotype and immunotherapy. The Journal of Clinical Investigation. PMID 32027624 DOI: 10.1172/Jci134402  0.458
2020 Webb P, Neville MC, Baumgartner-Wilson H, Post MD, Goodspeed A, Bitler BG. Abstract A30: Claudin-4-dependent mechanisms of high-grade serous ovarian cancer progression Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Ovca19-A30  0.522
2020 Bitler BG, Sawyer B, Qamar L, Richer JK, Behbakht K, Schlaepfer IR. Abstract 5029: Targeting fatty acid oxidation to promote anoikis and inhibit ovarian cancer progression Tumor Biology. DOI: 10.1158/1538-7445.Am2020-5029  0.383
2020 Moroney MR, Bitler BG, Corr BR. CTNNB1 Mutations are Associated with Decreased Disease-free Survival in a Low Risk Endometrial Cancer Group: An Analysis of the TCGA Database Gynecologic Oncology. 158. DOI: 10.1016/J.Ygyno.2020.04.004  0.36
2020 Sawyer B, Qamar L, Behbakht K, Schlaepfer I, Bitler B. Inhibition of Carnitine Palmitoyltransferase 1A Attenuates Ovarian Cancer Dissemination Gynecologic Oncology. 156: e3. DOI: 10.1016/J.Ygyno.2019.11.042  0.383
2019 Watson ZL, Yamamoto TM, McMellen A, Kim H, Hughes CJ, Wheeler LJ, Post MD, Behbakht K, Bitler BG. Histone methyltransferases EHMT1 and EHMT2 (GLP/G9A) maintain PARP inhibitor resistance in high-grade serous ovarian carcinoma. Clinical Epigenetics. 11: 165. PMID 31775874 DOI: 10.1186/S13148-019-0758-2  0.334
2019 Rao DM, Shackleford MT, Bordeaux EK, Sottnik JL, Ferguson RL, Yamamoto TM, Wellberg EA, Bitler BG, Sikora MJ. Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine O-acyltransferase or Wnt secretion. The Journal of Biological Chemistry. PMID 31740580 DOI: 10.1074/Jbc.Ra119.009615  0.399
2019 Smith LP, Bitler BG, Richer JK, Christenson JL. Tryptophan catabolism in epithelial ovarian carcinoma. Trends in Cancer Research. 14: 1-9. PMID 31736606  0.346
2019 Park PH, Yamamoto TM, Li H, Alcivar AL, Xia B, Wang Y, Bernhardy AJ, Turner KM, Kossenkov AV, Watson ZL, Behbakht K, Casadei S, Swisher EM, Mischel PS, Johnson N, ... Bitler BG, et al. Amplification of the mutation-carrying BRCA2 allele promotes RAD51 loading and PARP inhibitor resistance in the absence of reversion mutations. Molecular Cancer Therapeutics. PMID 31575654 DOI: 10.1158/1535-7163.Mct-17-0256  0.459
2019 Wheeler LJ, Watson ZL, Qamar L, Yamamoto TM, Sawyer BT, Sullivan KD, Khanal S, Joshi M, Ferchaud-Roucher V, Smith H, Vanderlinden LA, Brubaker SW, Caino CM, Kim H, Espinosa JM, ... ... Bitler BG, et al. Multi-Omic Approaches Identify Metabolic and Autophagy Regulators Important in Ovarian Cancer Dissemination. Iscience. 19: 474-491. PMID 31437751 DOI: 10.1016/J.Isci.2019.07.049  0.401
2019 Ramzan AA, Bitler BG, Hicks D, Barner K, Qamar L, Behbakht K, Powell T, Jansson T, Wilson H. Adiponectin receptor agonist AdipoRon induces apoptotic cell death and suppresses proliferation in human ovarian cancer cells. Molecular and Cellular Biochemistry. PMID 31292831 DOI: 10.1007/S11010-019-03586-9  0.444
2019 Yamamoto TM, McMellen A, Watson ZL, Aguilera J, Ferguson R, Nurmemmedov E, Thakar T, Moldovan GL, Kim H, Cittelly DM, Joglar AM, Brennecke EP, Wilson H, Behbakht K, Sikora MJ, ... Bitler BG, et al. Activation of Wnt signaling promotes olaparib resistant ovarian cancer. Molecular Carcinogenesis. PMID 31219654 DOI: 10.1002/Mc.23064  0.414
2019 Dahl ES, Buj R, Leon KE, Newell JM, Imamura Y, Bitler BG, Snyder NW, Aird KM. Targeting IDH1 as a pro-senescent therapy in high-grade serous ovarian cancer. Molecular Cancer Research : McR. PMID 31110157 DOI: 10.1158/1541-7786.Mcr-18-1233  0.508
2019 Breed C, Hicks DA, Webb PG, Galimanis CE, Bitler BG, Behbakht K, Baumgartner HK. Ovarian Tumor Cell Expression of Claudin-4 Reduces Apoptotic Response to Paclitaxel. Molecular Cancer Research : McR. PMID 30606772 DOI: 10.1158/1541-7786.Mcr-18-0451  0.486
2019 Watson ZL, Bitler BG. Type I Protein Arginine Methyltransferases Overexpression Promotes Transformation and Potentiates Her2/Neu-Driven Tumorigenesis. Cancer Research. 79: 3-4. PMID 30602621 DOI: 10.1158/0008-5472.Can-18-3552  0.417
2019 Wheeler LJ, Watson ZL, Qamar L, McMellen A, Yamamoto T, Behbakht K, Bitler BG. Abstract GMM-058: CBX2 IDENTIFIED AS DRIVER OF ANOIKIS ESCAPE AND DISSEMINATION IN HIGH GRADE SEROUS OVARIAN CANCER Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Gmm-058  0.512
2019 Wheeler L, Watson Z, Qamar L, Yamamoto T, Behbakht K, Bitler B. Chromobox 2 protein identified as driver of anoikis-escape and disease progression in high grade serous ovarian cancer Gynecologic Oncology. 154: e25-e26. DOI: 10.1016/J.Ygyno.2019.03.220  0.405
2019 Wheeler L, Watson Z, Yamamoto T, Sullivan K, Bitler B. Whole genome CRISPR/Cas9 screen identifies established and novel genes required for ovarian cancer dissemination Gynecologic Oncology. 153: e2. DOI: 10.1016/J.Ygyno.2019.03.108  0.366
2018 Fukumoto T, Zhang R, Bitler BG. Epigenetic inhibitors for the precision treatment of -mutant ovarian cancers: what are the next steps? Expert Review of Precision Medicine and Drug Development. 3: 233-236. PMID 30525111 DOI: 10.1080/23808993.2018.1503050  0.308
2018 Wheeler LJ, Watson ZL, Qamar L, Yamamoto TM, Post MD, Berning AA, Spillman MA, Behbakht K, Bitler BG. CBX2 identified as driver of anoikis escape and dissemination in high grade serous ovarian cancer. Oncogenesis. 7: 92. PMID 30478317 DOI: 10.1038/s41389-018-0103-1  0.434
2018 Wu S, Fatkhutdinov N, Fukumoto T, Bitler BG, Park PH, Kossenkov AV, Trizzino M, Tang HY, Zhang L, Gardini A, Speicher DW, Zhang R. SWI/SNF catalytic subunits' switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells. Nature Communications. 9: 4116. PMID 30297712 DOI: 10.1038/S41467-018-06656-6  0.396
2018 Gordon MA, Babbs B, Cochrane DR, Bitler B, Richer JK. The long non-coding RNA MALAT1 promotes ovarian cancer progression by regulating RBFOX2-mediated alternative splicing. Molecular Carcinogenesis. PMID 30294913 DOI: 10.1002/Mc.22919  0.468
2018 Singha B, Harper SL, Goldman AR, Bitler BG, Aird KM, Borowsky ME, Cadungog MG, Liu Q, Zhang R, Jean S, Drapkin R, Speicher DW. CLIC1 and CLIC4 complement CA125 as a diagnostic biomarker panel for all subtypes of epithelial ovarian cancer. Scientific Reports. 8: 14725. PMID 30282979 DOI: 10.1038/S41598-018-32885-2  0.406
2018 Fukumoto T, Park PH, Wu S, Fatkhutdinov N, Karakashev S, Nacarelli T, Kossenkov AV, Speicher DW, Jean S, Zhang L, Wang TL, Shih IM, Conejo-Garcia JR, Bitler BG, Zhang R. Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer. Cell Reports. 22: 3393-3400. PMID 29590609 DOI: 10.1016/J.Celrep.2018.03.019  0.488
2018 Karakashev S, Zhu H, Wu S, Yokoyama Y, Bitler BG, Park PH, Lee JH, Kossenkov AV, Gaonkar KS, Yan H, Drapkin R, Conejo-Garcia JR, Speicher DW, Ordog T, Zhang R. CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity. Nature Communications. 9: 631. PMID 29434212 DOI: 10.1038/S41467-018-03031-3  0.561
2018 Bitler B, Yamamoto T, Bales E, Watson Z, Behbakht K, Johnson J. Abstract B37: Prevention of epithelial ovarian cancer by eliciting P4/RIPK1-dependent necroptosis Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Ovca17-B37  0.474
2018 Smith LP, Harrell LM, Christenson JL, Bitler B, Slansky J, Richer JK. Abstract 5137: Tryptophan catabolism in ovarian cancer Tumor Biology. DOI: 10.1158/1538-7445.Am2018-5137  0.41
2017 Karakashev S, Zhu H, Yokoyama Y, Zhao B, Fatkhutdinov N, Kossenkov AV, Wilson AJ, Simpkins F, Speicher D, Khabele D, Bitler BG, Zhang R. BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer. Cell Reports. 21: 3398-3405. PMID 29262321 DOI: 10.1016/J.Celrep.2017.11.095  0.507
2017 Bitler BG, Watson ZL, Wheeler LJ, Behbakht K. PARP inhibitors: Clinical utility and possibilities of overcoming resistance. Gynecologic Oncology. PMID 29037806 DOI: 10.1016/J.Ygyno.2017.10.003  0.41
2017 Bitler BG, Wu S, Park PH, Hai Y, Aird KM, Wang Y, Zhai Y, Kossenkov AV, Vara-Ailor A, Rauscher Iii FJ, Zou W, Speicher DW, Huntsman DG, Conejo-Garcia JR, Cho KR, et al. ARID1A-mutated ovarian cancers depend on HDAC6 activity. Nature Cell Biology. PMID 28737768 DOI: 10.1038/Ncb3582  0.415
2017 Baumgartner HK, Rudolph MC, Ramanathan P, Burns V, Webb P, Bitler BG, Stein T, Kobayashi K, Neville MC. Developmental Expression of Claudins in the Mammary Gland. Journal of Mammary Gland Biology and Neoplasia. PMID 28455726 DOI: 10.1007/S10911-017-9379-6  0.308
2017 Zhu H, Bengsch F, Svoronos N, Rutkowski MR, Bitler BG, Allegrezza MJ, Yokoyama Y, Bradner JE, Conejo-Garcia JR, Zhang R. Abstract AP31: TARGETING PD–L1/PD1 PATHWAY THROUGH BET PROTEIN INHIBITION IN EPITHELIAL OVARIAN CANCER Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Ovcasymp16-Ap31  0.371
2017 Bitler BG, Park PH, Hai Y, Aird KM, Wang Y, Huntsman DG, Cho KR, Christianson DW, Zhang R. Abstract AP25: INHIBITION OF HDAC ACTIVITY SELECTIVELY INHIBITS ARID1A–MUTATED OVARIAN CLEAR CELL CARCINOMA THROUGH A NOVEL P53 REGULATORY MECHANISM Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Ovcasymp16-Ap25  0.528
2016 Yokoyama Y, Zhu H, Lee JH, Kossenkov AV, Wu SY, Wickramasinghe JM, Yin X, Palozola KC, Gardini A, Showe LC, Zaret KS, Liu Q, Speicher D, Conejo-Garcia JR, Bradner JE, ... ... Bitler BG, et al. BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer. Cancer Research. 76: 6320-6330. PMID 27803105 DOI: 10.1158/0008-5472.Can-16-0854  0.527
2016 Aird KM, Iwasaki O, Kossenkov AV, Tanizawa H, Fatkhutdinov N, Bitler BG, Le L, Alicea G, Yang TL, Johnson FB, Noma KI, Zhang R. HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci. The Journal of Cell Biology. PMID 27799366 DOI: 10.1083/Jcb.201608026  0.323
2016 Goldman AR, Bitler BG, Schug Z, Conejo-Garcia JR, Zhang R, Speicher DW. The Primary Effect on the Proteome of ARID1A-Mutated Ovarian Clear Cell Carcinoma is Downregulation of the Mevalonate Pathway at the Post-Transcriptional Level. Molecular & Cellular Proteomics : McP. PMID 27654507 DOI: 10.1074/Mcp.M116.062539  0.425
2016 Zhu H, Bengsch F, Svoronos N, Rutkowski MR, Bitler BG, Allegrezza MJ, Yokoyama Y, Kossenkov AV, Bradner JE, Conejo-Garcia JR, Zhang R. BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression. Cell Reports. 16: 2829-2837. PMID 27626654 DOI: 10.1016/J.Celrep.2016.08.032  0.394
2016 Bitler BG, Aird KM, Zhang R. Epigenetic synthetic lethality in ovarian clear cell carcinoma: EZH2 and ARID1A mutations. Molecular & Cellular Oncology. 3: e1032476. PMID 27308548 DOI: 10.1080/23723556.2015.1032476  0.354
2016 Bitler B, Shih I, Zhang R. Abstract B16: Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated ovarian cancers. Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Ovca15-B16  0.463
2016 Bitler B, Garipov A, Shih IM, Zhang R. Abstract B30: Targeting EZH2 methyltransferase activity: A novel therapeutic approach to ARID1A-deficient cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-B30  0.558
2015 Zhu H, Ren S, Bitler BG, Aird KM, Tu Z, Skordalakes E, Zhu Y, Yan J, Sun Y, Zhang R. SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase. Cell Reports. PMID 26527005 DOI: 10.1016/J.Celrep.2015.09.083  0.456
2015 Bitler BG, Fatkhutdinov N, Zhang R. Potential therapeutic targets in ARID1A-mutated cancers. Expert Opinion On Therapeutic Targets. 1-4. PMID 26125128 DOI: 10.1517/14728222.2015.1062879  0.479
2015 Bitler BG, Aird KM, Garipov A, Li H, Amatangelo M, Kossenkov AV, Schultz DC, Liu Q, Shih IeM, Conejo-Garcia JR, Speicher DW, Zhang R. Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers. Nature Medicine. 21: 231-8. PMID 25686104 DOI: 10.1038/Nm.3799  0.45
2013 Bitler BG, Fink LS, Wei Z, Peterson JR, Zhang R. A high-content screening assay for small-molecule modulators of oncogene-induced senescence. Journal of Biomolecular Screening. 18: 1054-61. PMID 23733845 DOI: 10.1177/1087057113491827  0.374
2013 Aird KM, Zhang G, Li H, Tu Z, Bitler BG, Garipov A, Wu H, Wei Z, Wagner SN, Herlyn M, Zhang R. Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence. Cell Reports. 3: 1252-65. PMID 23562156 DOI: 10.1016/J.Celrep.2013.03.004  0.408
2013 Garipov A, Li H, Bitler BG, Thapa RJ, Balachandran S, Zhang R. NF-YA underlies EZH2 upregulation and is essential for proliferation of human epithelial ovarian cancer cells. Molecular Cancer Research : McR. 11: 360-9. PMID 23360797 DOI: 10.1158/1541-7786.Mcr-12-0661  0.435
2013 Horm TM, Bitler BG, Broka DM, Louderbough J, Schroeder JA. Abstract A78: MUC1 drives c-Met-dependent migration and scattering Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A78  0.76
2012 Horm TM, Bitler BG, Broka DM, Louderbough JM, Schroeder JA. MUC1 drives c-Met-dependent migration and scattering. Molecular Cancer Research : McR. 10: 1544-54. PMID 23193156 DOI: 10.1158/1541-7786.Mcr-12-0296  0.761
2012 Li H, Bitler BG, Vathipadiekal V, Maradeo ME, Slifker M, Creasy CL, Tummino PJ, Cairns P, Birrer MJ, Zhang R. ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches. Cancer Prevention Research (Philadelphia, Pa.). 5: 484-91. PMID 22144423 DOI: 10.1158/1940-6207.Capr-11-0414  0.401
2011 Tu Z, Aird KM, Bitler BG, Nicodemus JP, Beeharry N, Xia B, Yen TJ, Zhang R. Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence. Developmental Cell. 21: 1077-91. PMID 22137763 DOI: 10.1016/J.Devcel.2011.10.010  0.314
2011 Bitler BG, Nicodemus JP, Li H, Cai Q, Wu H, Hua X, Li T, Birrer MJ, Godwin AK, Cairns P, Zhang R. Wnt5a suppresses epithelial ovarian cancer by promoting cellular senescence. Cancer Research. 71: 6184-94. PMID 21816908 DOI: 10.1158/0008-5472.Can-11-1341  0.509
2011 Bitler BG, Nicodemus JP, Li H, Cai Q, Soring K, Birrer MJ, Connolly DC, Godwin AK, Cairns P, Wu H, Zhang R. Abstract 1230: Wnt5a-dependent induction of senescence suppresses epithelial ovarian cancer Cancer Research. 71: 1230-1230. DOI: 10.1158/1538-7445.Am2011-1230  0.505
2010 Bitler BG, Goverdhan A, Schroeder JA. MUC1 regulates nuclear localization and function of the epidermal growth factor receptor Journal of Cell Science. 123: 1716-1723. PMID 20406885 DOI: 10.1242/Jcs.062661  0.741
2010 Bitler BG, Schroeder JA. Anti-cancer therapies that utilize cell penetrating peptides Recent Patents On Anti-Cancer Drug Discovery. 5: 99-108. PMID 19961434 DOI: 10.2174/157489210790936252  0.688
2010 Bitler BG, Goverdhan A, Schroeder J. Abstract 270: Modulation of EGFR localization and transcriptional activity Cancer Research. 70: 270-270. DOI: 10.1158/1538-7445.Am10-270  0.763
2007 Pochampalli MR, Bitler BG, Schroeder JA. Transforming growth factor α-dependent cancer progression is modulated by Muc1 Cancer Research. 67: 6591-6598. PMID 17638868 DOI: 10.1158/0008-5472.Can-06-4518  0.695
Low-probability matches (unlikely to be authored by this person)
2023 Nguyen LL, Watson ZL, Ortega R, Woodruff ER, Jordan KR, Iwanaga R, Yamamoto TM, Bailey CA, Jeong AD, Guntupalli SR, Behbakht K, Gbaja V, Arnoult N, Chuong EB, Bitler BG. Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models. Biorxiv : the Preprint Server For Biology. PMID 36865165 DOI: 10.1101/2023.02.23.529773  0.3
2016 Wu S, Zhang R, Bitler BG. Arid1a controls tissue regeneration. Stem Cell Investigation. 3: 35. PMID 27582418 DOI: 10.21037/Sci.2016.07.07  0.294
2006 Matzkin LM, Watts TD, Bitler BG, Machado CA, Markow TA. Functional genomics of cactus host shifts in Drosophila mojavensis. Molecular Ecology. 15: 4635-43. PMID 17107489 DOI: 10.1111/J.1365-294X.2006.03102.X  0.286
2021 Steinhart B, Jordan KR, Bapat J, Post MD, Brubaker LW, Bitler BG, Wrobel J. The Spatial Context of Tumor-Infiltrating Immune Cells Associates with Improved Ovarian Cancer Survival. Molecular Cancer Research : McR. PMID 34615692 DOI: 10.1158/1541-7786.MCR-21-0411  0.261
2022 Huang TT, Burkett SS, Tandon M, Yamamoto TM, Gupta N, Bitler BG, Lee JM, Nair JR. Distinct roles of treatment schemes and BRCA2 on the restoration of homologous recombination DNA repair and PARP inhibitor resistance in ovarian cancer. Oncogene. PMID 36224341 DOI: 10.1038/s41388-022-02491-8  0.254
2021 Cari EL, Hagen-Lillevik S, Giornazi A, Post M, Komar AA, Appiah L, Bitler B, Polotsky AJ, Santoro N, Kieft J, Lai K, Johnson J. Integrated stress response control of granulosa cell translation and proliferation during normal ovarian follicle development. Molecular Human Reproduction. PMID 34314477 DOI: 10.1093/molehr/gaab050  0.249
2023 Bitler BG, Bailey CA, Yamamoto TM, McMellen A, Kim H, Watson ZL. Targeting BRPF3 moderately reverses olaparib resistance in high grade serous ovarian carcinoma. Molecular Carcinogenesis. PMID 37493106 DOI: 10.1002/mc.23610  0.243
2024 Greenwood A, Woodruff ER, Nguyen C, Piper C, Clauset A, Brubaker LW, Behbakht K, Bitler BG. Early Ovarian Cancer Detection in the Age of Fallopian Tube Precursors: A Systematic Review. Obstetrics and Gynecology. PMID 38176019 DOI: 10.1097/AOG.0000000000005496  0.238
2021 Sanders BE, Ku L, Walker P, Bitler BG. Assessing Genetic Variants in Matched Biocompartments From Patients With Serous Ovarian Cancer. Technology in Cancer Research & Treatment. 20: 15330338211027917. PMID 34169762 DOI: 10.1177/15330338211027917  0.236
2006 Elser JJ, Watts T, Bitler B, Markow TA. Ontogenetic coupling of growth rate with RNA and P contents in five species of Drosophila Functional Ecology. 20: 846-856. DOI: 10.1111/J.1365-2435.2006.01165.X  0.235
2019 Johnson J, Llerena Cari EM, Sam PK, Bales ES, Ryu S, Nel-Themaat L, Kallen AN, Polotsky AJ, Post MD, Orlicky DJ, Jordan K, Bitler BG. Expression and function of the PD-1 immune checkpoint in the human ovary and fallopian tube Fertility and Sterility. 112: e106. DOI: 10.1016/J.Fertnstert.2019.07.397  0.232
2024 Kleunen LV, Ahmadian M, Post MD, Wolsky RJ, Rickert C, Jordan K, Hu J, Richer JK, Marjon NA, Behbakht K, Sikora MJ, Bitler BG, Clauset A. The spatial structure of the tumor immune microenvironment can explain and predict patient response in high-grade serous carcinoma. Biorxiv : the Preprint Server For Biology. PMID 38352574 DOI: 10.1101/2024.01.26.577350  0.22
2011 Dang H, Klokk TI, Schaheen B, McLaughlin BM, Thomas AJ, Durns TA, Bitler BG, Sandvig K, Fares H. Derlin-dependent retrograde transport from endosomes to the Golgi apparatus. Traffic (Copenhagen, Denmark). 12: 1417-31. PMID 21722281 DOI: 10.1111/J.1600-0854.2011.01243.X  0.219
2006 Pfeiler E, Bitler BG, Ramsey JM, Palacios-Cardiel C, Markow TA. Genetic variation, population structure, and phylogenetic relationships of Triatoma rubida and T. recurva (Hemiptera: Reduviidae: Triatominae) from the Sonoran Desert, insect vectors of the Chagas' disease parasite Trypanosoma cruzi. Molecular Phylogenetics and Evolution. 41: 209-21. PMID 16934496 DOI: 10.1016/J.Ympev.2006.07.001  0.218
2021 Clauset A, Behbakht K, Bitler BG. Decoding the dynamic tumor microenvironment. Science Advances. 7. PMID 34088677 DOI: 10.1126/sciadv.abi5904  0.216
2022 Haag JG, Wolsky RJ, Moroney MR, Sheren J, Sheeder J, Bitler BG, Corr BR. Clinicopathologic Evaluation of CTNNB1 Mutations in High-Intermediate Risk Endometrial Endometrioid Carcinoma. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. PMID 35283443 DOI: 10.1097/PGP.0000000000000865  0.215
2021 Lin J, Guo D, Liu H, Zhou W, Wang C, Müller I, Kossenkov AV, Drapkin R, Bitler BG, Helin K, Zhang R. The SETDB1-TRIM28 Complex Suppresses Antitumor Immunity. Cancer Immunology Research. PMID 34848497 DOI: 10.1158/2326-6066.CIR-21-0754  0.21
2020 Luu TH, Cari EL, Bales E, Lucas E, Bitler B, Tamburini B, Johnson J. Highly Increased Vascular Density In Corpora Lutea Of Pd-L1 Knockout Mice Compared To Controls Fertility and Sterility. 113. DOI: 10.1016/J.Fertnstert.2020.02.018  0.208
2023 Pasquesi GIM, Allen H, Ivancevic A, Barbachano-Guerrero A, Joyner O, Guo K, Simpson DM, Gapin K, Horton I, Nguyen L, Yang Q, Warren CJ, Florea LD, Bitler BG, Santiago ML, et al. Regulation of human interferon signaling by transposon exonization. Biorxiv : the Preprint Server For Biology. PMID 37745311 DOI: 10.1101/2023.09.11.557241  0.188
2024 Uboveja A, Huang Z, Buj R, Amalric A, Wang H, Tangudu NK, Cole AR, Megill E, Kantner D, Chatoff A, Ahmad H, Marcinkiewicz MM, Disharoon JA, Graff S, Dahl ES, ... ... Bitler BG, et al. αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation. Biorxiv : the Preprint Server For Biology. PMID 38370789 DOI: 10.1101/2024.02.06.578742  0.166
2022 Johnson J, Kim SY, Sam PK, Asokan R, Cari EL, Bales ES, Luu TH, Perez L, Kallen AN, Nel-Themaat L, Polotsky AJ, Post MD, Orlicky DJ, Jordan KR, Bitler BG. Expression and T cell Regulatory Action of the PD-1 Immune Checkpoint in the Ovary and Fallopian Tube. American Journal of Reproductive Immunology (New York, N.Y. : 1989). PMID 36394352 DOI: 10.1111/aji.13649  0.112
2023 Seal S, Bitler BG, Ghosh D. SMASH: Scalable Method for Analyzing Spatial Heterogeneity of genes in spatial transcriptomics data. Biorxiv : the Preprint Server For Biology. PMID 36993287 DOI: 10.1101/2023.03.23.533980  0.111
2023 Seal S, Bitler BG, Ghosh D. SMASH: Scalable Method for Analyzing Spatial Heterogeneity of genes in spatial transcriptomics data. Plos Genetics. 19: e1010983. PMID 37862362 DOI: 10.1371/journal.pgen.1010983  0.11
2023 Ahmadian M, Rickert C, Minic A, Wrobel J, Bitler BG, Xing F, Angelo M, Hsieh EWY, Ghosh D, Jordan KR. A platform-independent framework for phenotyping of multiplex tissue imaging data. Plos Computational Biology. 19: e1011432. PMID 37733781 DOI: 10.1371/journal.pcbi.1011432  0.047
2022 Seal S, Wrobel J, Johnson AM, Nemenoff RA, Schenk EL, Bitler BG, Jordan KR, Ghosh D. On clustering for cell-phenotyping in multiplex immunohistochemistry (mIHC) and multiplexed ion beam imaging (MIBI) data. Bmc Research Notes. 15: 215. PMID 35725622 DOI: 10.1186/s13104-022-06097-x  0.038
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