| Year |
Citation |
Score |
| 2023 |
Yap J, Yuan J, Ng WH, Chen GB, Sim YRM, Goh KC, Teo J, Lim TYH, Goay SM, Teo JHJ, Lao Z, Lam P, Sabapathy K, Hu J. BRAF(V600E) mutation together with loss of Trp53 or pTEN drives the origination of hairy cell leukemia from B-lymphocytes. Molecular Cancer. 22: 125. PMID 37543582 DOI: 10.1186/s12943-023-01817-8 |
0.34 |
|
| 2020 |
Yuan J, Dong X, Yap J, Hu J. The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy. Journal of Hematology & Oncology. 13: 113. PMID 32807225 DOI: 10.1186/S13045-020-00949-4 |
0.384 |
|
| 2020 |
Degirmenci U, Wang M, Hu J. Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy. Cells. 9. PMID 31941155 DOI: 10.3390/Cells9010198 |
0.419 |
|
| 2019 |
Yap J, Yuan J, Tee ZH, Huang X, Ng WH, Hu J. Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods. Journal of Visualized Experiments : Jove. PMID 31380842 DOI: 10.3791/59795 |
0.358 |
|
| 2018 |
Yuan J, Ng WH, Tian Z, Yap J, Baccarini M, Chen Z, Hu J. Activating mutations in MEK1 enhance homodimerization and promote tumorigenesis. Science Signaling. 11. PMID 30377225 DOI: 10.1126/Scisignal.Aar6795 |
0.371 |
|
| 2018 |
Yuan J, Ng WH, Yap J, Chia B, Huang X, Wang M, Hu J. The AMPK inhibitor overcomes the paradoxical effect of RAF inhibitors through blocking the phospho-Ser-621 in the carboxyl-terminus of CRAF. The Journal of Biological Chemistry. PMID 30030377 DOI: 10.1074/Jbc.Ra118.004597 |
0.366 |
|
| 2018 |
Yuan J, Ng WH, Lam PYP, Wang Y, Xia H, Yap J, Guan SP, Lee ASG, Wang M, Baccarini M, Hu J. The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutants. Oncogene. PMID 29930381 DOI: 10.1038/S41388-018-0365-2 |
0.36 |
|
| 2016 |
Xu X, Wang X, Todd EM, Jaeger ER, Vella JL, Mooren OL, Feng Y, Hu J, Cooper JA, Morley SC, Huang YH. Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration. Journal of Immunology (Baltimore, Md. : 1950). PMID 27465533 DOI: 10.4049/Jimmunol.1600874 |
0.446 |
|
| 2015 |
Chung JJ, Huber TB, Gödel M, Jarad G, Hartleben B, Kwoh C, Keil A, Karpitskiy A, Hu J, Huh CJ, Cella M, Gross RW, Miner JH, Shaw AS. Albumin-associated free fatty acids induce macropinocytosis in podocytes. The Journal of Clinical Investigation. 125: 2307-16. PMID 25915582 DOI: 10.1172/Jci79641 |
0.332 |
|
| 2015 |
Hu J, Ahuja LG, Meharena HS, Kannan N, Kornev AP, Taylor SS, Shaw AS. Kinase regulation by hydrophobic spine assembly in cancer. Molecular and Cellular Biology. 35: 264-76. PMID 25348715 DOI: 10.1128/Mcb.00943-14 |
0.328 |
|
| 2014 |
Wang X, Boyken SE, Hu J, Xu X, Rimer RP, Shea MA, Shaw AS, Andreotti AH, Huang YH. Calmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production. Science Signaling. 7: ra74. PMID 25097034 DOI: 10.1126/Scisignal.2005147 |
0.314 |
|
| 2014 |
Hu J, Oda SK, Shotts K, Donovan EE, Strauch P, Pujanauski LM, Victorino F, Al-Shami A, Fujiwara Y, Tigyi G, Oravecz T, Pelanda R, Torres RM. Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response. Journal of Immunology (Baltimore, Md. : 1950). 193: 85-95. PMID 24890721 DOI: 10.4049/Jimmunol.1300429 |
0.54 |
|
| 2014 |
Shaw AS, Kornev AP, Hu J, Ahuja LG, Taylor SS. Kinases and pseudokinases: lessons from RAF. Molecular and Cellular Biology. 34: 1538-46. PMID 24567368 DOI: 10.1128/Mcb.00057-14 |
0.371 |
|
| 2013 |
Hu J, Stites EC, Yu H, Germino EA, Meharena HS, Stork PJ, Kornev AP, Taylor SS, Shaw AS. Allosteric activation of functionally asymmetric RAF kinase dimers. Cell. 154: 1036-46. PMID 23993095 DOI: 10.1016/J.Cell.2013.07.046 |
0.36 |
|
| 2013 |
Taylor SS, Shaw A, Hu J, Meharena HS, Kornev A. Pseudokinases from a structural perspective. Biochemical Society Transactions. 41: 981-6. PMID 23863167 DOI: 10.1042/Bst20130120 |
0.371 |
|
| 2012 |
Banchereau J, Zurawski S, Thompson-Snipes L, Blanck JP, Clayton S, Munk A, Cao Y, Wang Z, Khandelwal S, Hu J, McCoy WH, Palucka KA, Reiter Y, Fremont DH, Zurawski G, et al. Immunoglobulin-like transcript receptors on human dermal CD14+ dendritic cells act as a CD8-antagonist to control cytotoxic T cell priming. Proceedings of the National Academy of Sciences of the United States of America. 109: 18885-90. PMID 23112154 DOI: 10.1073/Pnas.1205785109 |
0.379 |
|
| 2011 |
Hu J, Yu H, Kornev AP, Zhao J, Filbert EL, Taylor SS, Shaw AS. Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF. Proceedings of the National Academy of Sciences of the United States of America. 108: 6067-72. PMID 21441104 DOI: 10.1073/Pnas.1102554108 |
0.333 |
|
| 2008 |
Hu J, Strauch P, Rubtsov A, Donovan EE, Pelanda R, Torres RM. Lsc activity is controlled by oligomerization and regulates integrin adhesion. Molecular Immunology. 45: 1825-36. PMID 18157933 DOI: 10.1016/J.Molimm.2007.11.002 |
0.692 |
|
| 2005 |
Rubtsov A, Strauch P, Digiacomo A, Hu J, Pelanda R, Torres RM. Lsc regulates marginal-zone B cell migration and adhesion and is required for the IgM T-dependent antibody response. Immunity. 23: 527-38. PMID 16286020 DOI: 10.1016/J.Immuni.2005.09.018 |
0.701 |
|
| 2002 |
Xu LG, Wu M, Hu J, Zhai Z, Shu HB. Identification of downstream genes up-regulated by the tumor necrosis factor family member TALL-1. Journal of Leukocyte Biology. 72: 410-6. PMID 12149433 DOI: 10.1189/Jlb.72.2.410 |
0.397 |
|
| 2001 |
Hu J, Lei Y, Hong X, Lu Z, Zhai Z. Rapid senescence induced by overexpression of p53 in NIH3T3 cells Chinese Science Bulletin. 46: 653-656. DOI: 10.1007/Bf03182827 |
0.347 |
|
| 2000 |
Jiang Z, Hong X, Long H, Hu J, Zhai Z. Ceramides induce apoptosis in HeLa cells and enhance cytochrome c-induced apoptosis in Xenopus egg extracts. Cellular and Molecular Life Sciences : Cmls. 57: 1117-25. PMID 10961348 DOI: 10.1007/Pl00000748 |
0.334 |
|
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