Derek Boerboom, Ph.D. - Publications

Affiliations: 
2000 Université de Montréal, Montréal, Canada 
Area:
Molecular Biology

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ménard A, Abou Nader N, Levasseur A, St-Jean G, Le Roy MLG, Boerboom D, Benoit-Biancamano MO, Boyer A. Targeted disruption of Lats1 and Lats2 in mice impairs adrenal cortex development and alters adrenocortical cell fate. Endocrinology. PMID 32243503 DOI: 10.1210/endocr/bqaa052  0.32
2019 St-Jean G, Tsoi M, Abedini A, Levasseur A, Rico C, Morin M, Djordjevic B, Miinalainen I, Kaarteenaho R, Paquet M, Gévry N, Boyer A, Vanderhyden B, Boerboom D. and are required for the maintenance of multipotency in the Müllerian duct mesenchyme. Development (Cambridge, England). PMID 31575647 DOI: 10.1242/dev.180430  0.32
2019 Abou Nader N, Levasseur A, Zhang X, Boerboom D, Nagano MC, Boyer A. Yes-associated protein expression in germ cells is dispensable for spermatogenesis in mice. Genesis (New York, N.Y. : 2000). e23330. PMID 31386299 DOI: 10.1002/dvg.23330  0.32
2019 Zamberlam G, Lapointe E, Abedini A, Rico C, Godin P, Paquet M, DeMayo FJ, Boerboom D. SFRP4 is a negative regulator of ovarian follicle development and female fertility. Endocrinology. PMID 30942852 DOI: 10.1210/en.2019-00212  0.96
2018 St-Jean G, Boyer A, Zamberlam G, Godin P, Paquet M, Boerboom D. Targeted ablation of Wnt4 and Wnt5a in Müllerian duct mesenchyme impedes endometrial gland development and causes partial Müllerian agenesis. Biology of Reproduction. PMID 30010727 DOI: 10.1093/biolre/ioy160  0.32
2018 Li Y, Schang G, Wang Y, Zhou X, Levasseur A, Boyer A, Deng CX, Treier M, Boehm U, Boerboom D, Bernard DJ. Conditional deletion of FOXL2 and SMAD4 in gonadotropes of adult mice causes isolated FSH deficiency. Endocrinology. PMID 29800110 DOI: 10.1210/en.2018-00100  0.32
2017 Levasseur A, St-Jean G, Paquet M, Boerboom D, Boyer A. Targeted disruption of YAP and TAZ impairs the maintenance of the adrenal cortex. Endocrinology. PMID 28938438 DOI: 10.1210/en.2017-00098  0.32
2017 Ciarlillo D, Celeste C, Carmeliet P, Boerboom D, Theoret C. A hypoxia response element in the Vegfa promoter is required for basal Vegfa expression in skin and for optimal granulation tissue formation during wound healing in mice. Plos One. 12: e0180586. PMID 28686658 DOI: 10.1371/journal.pone.0180586  0.48
2017 Levasseur A, Paquet M, Boerboom D, Boyer A. YAP and WWTR1 regulate the expression of sex determining genes in Sertoli cells, but their inactivation does not cause sex reversal. Biology of Reproduction. PMID 28637242 DOI: 10.1093/biolre/iox057  0.32
2017 Feng Y, Cui P, Lu X, Hsueh B, Möller Billig F, Zarnescu Yanez L, Tomer R, Boerboom D, Carmeliet P, Deisseroth K, Hsueh AJ. CLARITY reveals dynamics of ovarian follicular architecture and vasculature in three-dimensions. Scientific Reports. 7: 44810. PMID 28333125 DOI: 10.1038/Srep44810  0.48
2016 Boyer A, Girard M, Thimmahahalli DS, Levasseur A, Céleste C, Paquet M, Duggavathi R, Boerboom D. mTOR Regulates Gap Junction Alpha-1 Protein Trafficking in Sertoli Cells and Is Required for the Maintenance of Spermatogenesis in Mice. Biology of Reproduction. PMID 27281705 DOI: 10.1095/biolreprod.115.138016  0.6
2015 Abedini A, Zamberlam G, Lapointe E, Tourigny C, Boyer A, Paquet M, Hayashi K, Honda H, Kikuchi A, Price C, Boerboom D. WNT5a is required for normal ovarian follicle development and antagonizes gonadotropin responsiveness in granulosa cells by suppressing canonical WNT signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26667040 DOI: 10.1096/fj.15-280313  1
2015 Nadeau MÈ, Rico C, Tsoi M, Vivancos M, Filimon S, Paquet M, Boerboom D. Pharmacological targeting of valosin containing protein (VCP) induces DNA damage and selectively kills canine lymphoma cells. Bmc Cancer. 15: 479. PMID 26104798 DOI: 10.1186/s12885-015-1489-1  1
2015 Abedini A, Zamberlam G, Boerboom D, Price CA. Non-canonical WNT5A is a potential regulator of granulosa cell function in cattle. Molecular and Cellular Endocrinology. 403: 39-45. PMID 25600632 DOI: 10.1016/j.mce.2015.01.017  1
2015 Boerboom D, Kumar V, Boyer A, Wang Y, Lambrot R, Zhou X, Rico C, Boehm U, Paquet M, Céleste C, Kimmins S, Bernard DJ. β-catenin stabilization in gonadotropes impairs FSH synthesis in male mice in vivo. Endocrinology. 156: 323-33. PMID 25343272 DOI: 10.1210/En.2014-1296  1
2014 Rico C, Dodelet-Devillers A, Paquet M, Tsoi M, Lapointe E, Carmeliet P, Boerboom D. HIF1 activity in granulosa cells is required for FSH-regulated Vegfa expression and follicle survival in mice. Biology of Reproduction. 90: 135. PMID 24855100 DOI: 10.1095/biolreprod.113.115634  1
2013 Tsoi M, Laguë MN, Boyer A, Paquet M, Nadeau MÈ, Boerboom D. Anti-VEGFA Therapy Reduces Tumor Growth and Extends Survival in a Murine Model of Ovarian Granulosa Cell Tumor. Translational Oncology. 6: 226-33. PMID 23730402  0.32
2013 Tran S, Zhou X, Lafleur C, Calderon MJ, Ellsworth BS, Kimmins S, Boehm U, Treier M, Boerboom D, Bernard DJ. Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice. Molecular Endocrinology (Baltimore, Md.). 27: 407-21. PMID 23340250 DOI: 10.1210/Me.2012-1286  1
2013 Tsoi M, Laguë MN, Boyer A, Paquet M, Nadeau ME, Boerboom D. Anti-VEGFA Therapy Reduces Tumor Growth and Extends Survival in a Murine Model of Ovarian Granulosa Cell Tumor Translational Oncology. 6: 226-233. DOI: 10.1593/tlo.13136  1
2012 Lapointe E, Boyer A, Rico C, Paquet M, Franco HL, Gossen J, DeMayo FJ, Richards JS, Boerboom D. FZD1 regulates cumulus expansion genes and is required for normal female fertility in mice. Biology of Reproduction. 87: 104. PMID 22954793 DOI: 10.1095/biolreprod.112.102608  1
2012 Rico C, Laguë MN, Lefèvre P, Tsoi M, Dodelet-Devillers A, Kumar V, Lapointe E, Paquet M, Nadeau MÈ, Boerboom D. Pharmacological targeting of mammalian target of rapamycin inhibits ovarian granulosa cell tumor growth. Carcinogenesis. 33: 2283-92. PMID 22871496 DOI: 10.1093/carcin/bgs263  1
2012 Laguë MN, Romieu-Mourez R, Bonneil É, Boyer A, Pouletty N, Mes-Masson AM, Thibault P, Nadeau MÈ, Boerboom D. Proteomic profiling of a mouse model for ovarian granulosa cell tumor identifies VCP as a highly sensitive serum tumor marker in several human cancers. Plos One. 7: e42470. PMID 22870330 DOI: 10.1371/Journal.Pone.0042470  1
2012 Boyer A, Yeh JR, Zhang X, Paquet M, Gaudin A, Nagano MC, Boerboom D. CTNNB1 signaling in sertoli cells downregulates spermatogonial stem cell activity via WNT4. Plos One. 7: e29764. PMID 22253774 DOI: 10.1371/journal.pone.0029764  1
2012 Deschene K, Céleste C, Boerboom D, Theoret CL. Hypoxia regulates the expression of extracellular matrix associated proteins in equine dermal fibroblasts via HIF1. Journal of Dermatological Science. 65: 12-8. PMID 21999945 DOI: 10.1016/j.jdermsci.2011.09.006  0.6
2012 Richards JS, Fan HY, Liu Z, Tsoi M, Laguë MN, Boyer A, Boerboom D. Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis. Oncogene. 31: 1504-20. PMID 21860425 DOI: 10.1038/onc.2011.341  0.32
2011 Paquet M, El-Warrak AO, Laguë MN, Boerboom D. Atypical caudal duplication with phenotypic sex reversal in a dog. Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 23: 1037-40. PMID 21908371 DOI: 10.1177/1040638711407682  1
2011 Boerboom D, Lafond JF, Zheng X, Lapointe E, Mittaz L, Boyer A, Pritchard MA, DeMayo FJ, Mort JS, Drolet R, Richards JS. Partially redundant functions of Adamts1 and Adamts4 in the perinatal development of the renal medulla. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 1806-14. PMID 21584905 DOI: 10.1002/Dvdy.22662  1
2011 Deschene K, Céleste C, Boerboom D, Theoret CL. Constitutive expression of hypoxia-inducible factor-1 α in keratinocytes during the repair of skin wounds in horses. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 19: 250-9. PMID 21362093 DOI: 10.1111/j.1524-475X.2010.00663.x  0.6
2011 Lapointe E, Boerboom D. WNT signaling and the regulation of ovarian steroidogenesis. Frontiers in Bioscience (Scholar Edition). 3: 276-85. PMID 21196376  1
2011 Franco HL, Dai D, Lee KY, Rubel CA, Roop D, Boerboom D, Jeong JW, Lydon JP, Bagchi IC, Bagchi MK, DeMayo FJ. WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1176-87. PMID 21163860 DOI: 10.1096/fj.10-175349  1
2010 Laguë MN, Detmar J, Paquet M, Boyer A, Richards JS, Adamson SL, Boerboom D. Decidual PTEN expression is required for trophoblast invasion in the mouse. American Journal of Physiology. Endocrinology and Metabolism. 299: E936-46. PMID 20858757 DOI: 10.1152/ajpendo.00255.2010  1
2010 Brown HM, Dunning KR, Robker RL, Boerboom D, Pritchard M, Lane M, Russell DL. ADAMTS1 cleavage of versican mediates essential structural remodeling of the ovarian follicle and cumulus-oocyte matrix during ovulation in mice. Biology of Reproduction. 83: 549-57. PMID 20592310 DOI: 10.1095/biolreprod.110.084434  1
2010 Boyer A, Lapointe E, Zheng X, Cowan RG, Li H, Quirk SM, DeMayo FJ, Richards JS, Boerboom D. WNT4 is required for normal ovarian follicle development and female fertility. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3010-25. PMID 20371632 DOI: 10.1096/Fj.09-145789  1
2010 Boyer A, Goff AK, Boerboom D. WNT signaling in ovarian follicle biology and tumorigenesis. Trends in Endocrinology and Metabolism: Tem. 21: 25-32. PMID 19875303 DOI: 10.1016/j.tem.2009.08.005  0.56
2009 Nadeau ME, Kaartinen MJ, Laguë MN, Paquet M, Huneault LM, Boerboom D. A mouse surgical model for metastatic ovarian granulosa cell tumor. Comparative Medicine. 59: 553-6. PMID 20034430  1
2009 Zheng X, Boerboom D, Carrière PD. Transforming growth factor-beta1 inhibits luteinization and promotes apoptosis in bovine granulosa cells. Reproduction (Cambridge, England). 137: 969-77. PMID 19307427 DOI: 10.1530/Rep-08-0365  0.32
2009 Boyer A, Paquet M, Laguë MN, Hermo L, Boerboom D. Dysregulation of WNT/CTNNB1 and PI3K/AKT signaling in testicular stromal cells causes granulosa cell tumor of the testis. Carcinogenesis. 30: 869-78. PMID 19237610 DOI: 10.1093/carcin/bgp051  1
2008 Paquet M, Penney J, Boerboom D. Lateral femoral hernias in a line of FVB/NHsd mice: a new confounding lesion linked to genetic background? Comparative Medicine. 58: 395-8. PMID 18724783  1
2008 Laguë MN, Paquet M, Fan HY, Kaartinen MJ, Chu S, Jamin SP, Behringer RR, Fuller PJ, Mitchell A, Doré M, Huneault LM, Richards JS, Boerboom D. Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression. Carcinogenesis. 29: 2062-72. PMID 18687666 DOI: 10.1093/Carcin/Bgn186  1
2008 Boyer A, Hermo L, Paquet M, Robaire B, Boerboom D. Seminiferous tubule degeneration and infertility in mice with sustained activation of WNT/CTNNB1 signaling in sertoli cells. Biology of Reproduction. 79: 475-85. PMID 18480464 DOI: 10.1095/biolreprod.108.068627  1
2006 Brown KA, Boerboom D, Bouchard N, Doré M, Lussier JG, Sirois J. Human chorionic gonadotropin-dependent induction of an equine aldo-keto reductase (AKR1C23) with 20alpha-hydroxysteroid dehydrogenase activity during follicular luteinization in vivo. Journal of Molecular Endocrinology. 36: 449-61. PMID 16720716 DOI: 10.1677/jme.1.01987  1
2006 Boerboom D, White LD, Dalle S, Courty J, Richards JS. Dominant-stable β-catenin expression causes cell fate alterations and Wnt signaling antagonist expression in a murine granulosa cell tumor model Cancer Research. 66: 1964-1973. PMID 16488995 DOI: 10.1158/0008-5472.CAN-05-3493  1
2005 Boerboom D, Paquet M, Hsieh M, Liu J, Jamin SP, Behringer RR, Sirois J, Taketo MM, Richards JS. Misregulated Wnt/beta-catenin signaling leads to ovarian granulosa cell tumor development. Cancer Research. 65: 9206-15. PMID 16230381 DOI: 10.1158/0008-5472.Can-05-1024  1
2005 Hsieh M, Boerboom D, Shimada M, Lo Y, Parlow AF, Luhmann UF, Berger W, Richards JS. Mice null for Frizzled4 (Fzd4-/-) are infertile and exhibit impaired corpora lutea formation and function. Biology of Reproduction. 73: 1135-46. PMID 16093361 DOI: 10.1095/biolreprod.105.042739  0.32
2005 Richards JS, Hernandez-Gonzalez I, Gonzalez-Robayna I, Teuling E, Lo Y, Boerboom D, Falender AE, Doyle KH, LeBaron RG, Thompson V, Sandy JD. Regulated expression of ADAMTS family members in follicles and cumulus oocyte complexes: evidence for specific and redundant patterns during ovulation. Biology of Reproduction. 72: 1241-55. PMID 15659705 DOI: 10.1095/Biolreprod.104.038083  1
2005 Sayasith K, Bouchard N, Boerboom D, Brown KA, Doré M, Sirois J. Molecular characterization of equine P-selectin (CD62P) and its regulation in ovarian follicles during the ovulatory process. Biology of Reproduction. 72: 736-44. PMID 15564599 DOI: 10.1095/biolreprod.104.034710  1
2004 Brown KA, Boerboom D, Bouchard N, Doré M, Lussier JG, Sirois J. Human chorionic gonadotropin-dependent regulation of 17beta-hydroxysteroid dehydrogenase type 4 in preovulatory follicles and its potential role in follicular luteinization. Endocrinology. 145: 1906-15. PMID 14726434 DOI: 10.1210/en.2003-1715  1
2004 Boerboom D, Brown KA, Vaillancourt D, Poitras P, Goff AK, Watanabe K, Doré M, Sirois J. Expression of key prostaglandin synthases in equine endometrium during late diestrus and early pregnancy. Biology of Reproduction. 70: 391-9. PMID 14561653 DOI: 10.1095/biolreprod.103.020800  1
2003 Boerboom D, Russell DL, Richards JS, Sirois J. Regulation of transcripts encoding ADAMTS-1 (a disintegrin and metalloproteinase with thrombospondin-like motifs-1) and progesterone receptor by human chorionic gonadotropin in equine preovulatory follicles. Journal of Molecular Endocrinology. 31: 473-85. PMID 14664708 DOI: 10.1677/jme.0.0310473  1
2003 Boerboom D, Mulon PY, Desrochers A. Duodenal obstruction caused by malposition of the gallbladder in a heifer Journal of the American Veterinary Medical Association. 223: 1475-1477+1435. PMID 14627100 DOI: 10.2460/javma.2003.223.1475  1
2003 Sirois J, Boerboom D, Sayasith K. Prostaglandin Biosynthesis and Action in the Ovary The Ovary: Second Edition. 233-247. DOI: 10.1016/B978-012444562-8/50014-8  1
2002 Boutemmine D, Bouchard N, Boerboom D, Jones HE, Goff AK, Dore M, Sirois J. Molecular Characterization of Canine Prostaglandin G/H Synthase-2 and Regulation in Prostatic Adenocarcinoma Cells in Vitro. Endocrinology. 143: 1134-1143. PMID 28201358 DOI: 10.1210/endo.143.3.8695  1
2002 Boutemmine D, Bouchard N, Boerboom D, Jones HE, Goff AK, Doré M, Sirois J. Molecular characterization of canine prostaglandin G/H synthase-2 and regulation in prostatic adenocarcinoma cells in vitro. Endocrinology. 143: 1134-43. PMID 11861541 DOI: 10.1210/endo.143.3.8695  1
2001 Liu J, Antaya M, Goff AK, Boerboom D, Silversides DW, Lussier JG, Sirois J. Molecular characterization of bovine prostaglandin G/H synthase-2 and regulation in uterine stromal cells. Biology of Reproduction. 64: 983-91. PMID 11207216 DOI: 10.1095/biolreprod64.3.983  1
2001 Boerboom D, Sirois J. Equine P450 cholesterol side-chain cleavage and 3 beta-hydroxysteroid dehydrogenase/delta(5)-delta(4) isomerase: molecular cloning and regulation of their messenger ribonucleic acids in equine follicles during the ovulatory process. Biology of Reproduction. 64: 206-15. PMID 11133676 DOI: 10.1095/biolreprod64.1.206  1
2000 Boerboom D, Pilon N, Behdjani R, Silversides DW, Sirois J. Expression and Regulation of Transcripts Encoding Two Members of the NR5A Nuclear Receptor Subfamily of Orphan Nuclear Receptors, Steroidogenic Factor-1 and NR5A2, in Equine Ovarian Cells during the Ovulatory Process* *This study was supported by Natural Sciences and Engineering Research Council of Canada Grant OPG0171135. The nucleotide sequences reported in this paper have been submitted to GenBank, with accession numbers AF157626, AF168796, AF203911, and AF203913. Endocrinology. 141: 4647-4656. PMID 28204327 DOI: 10.1210/endo.141.12.7808  1
2000 Boerboom D, Pilon N, Behdjani R, Silversides DW, Sirois J. Expression and regulation of transcripts encoding two members of the NR5A nuclear receptor subfamily of orphan nuclear receptors, steroidogenic factor-1 and NR5A2, in equine ovarian cells during the ovulatory process. Endocrinology. 141: 4647-56. PMID 11108279 DOI: 10.1210/endo.141.12.7808  1
1999 Boerboom D, Kerban A, Sirois J. Dual Regulation of Promoter II- and Promoter 1f-Derived Cytochrome P450 Aromatase Transcripts in Equine Granulosa Cells during Human Chorionic Gonadotropin-Induced Ovulation: A Novel Model for the Study of Aromatase Promoter Switching1. Endocrinology. 140: 4133-4141. PMID 28201009 DOI: 10.1210/endo.140.9.6951  1
1999 Liu J, Antaya M, Boerboom D, Lussier JG, Silversides DW, Sirois J. The delayed activation of the prostaglandin G/H synthase-2 promoter in bovine granulosa cells is associated with down-regulation of truncated upstream stimulatory factor-2. The Journal of Biological Chemistry. 274: 35037-45. PMID 10574982 DOI: 10.1074/jbc.274.49.35037  1
1999 Boerboom D, Kerban A, Sirois J. Dual regulation of promoter II- and promoter 1f-derived cytochrome P450 aromatase transcripts in equine granulosa cells during human chorionic gonadotropin-induced ovulation: a novel model for the study of aromatase promoter switching. Endocrinology. 140: 4133-41. PMID 10465286 DOI: 10.1210/endo.140.9.6951  1
1999 Kerban A, Boerboom D, Sirois J. Human chorionic gonadotropin induces an inverse regulation of steroidogenic acute regulatory protein messenger ribonucleic acid in theca interna and granulosa cells of equine preovulatory follicles. Endocrinology. 140: 667-74. PMID 9927292 DOI: 10.1210/endo.140.2.6499  1
1998 Boerboom D, Sirois J. Molecular characterization of equine prostaglandin G/H synthase-2 and regulation of its messenger ribonucleic acid in preovulatory follicles. Endocrinology. 139: 1662-70. PMID 9528947 DOI: 10.1210/endo.139.4.5898  1
1994 Tillmann U, Wagner J, Boerboom D, Westphal H, Tremblay ML. Nuclear localization and cell cycle regulation of a murine protein tyrosine phosphatase Molecular and Cellular Biology. 14: 3030-3040. PMID 8164659 DOI: 10.1128/MCB.14.5.3030  1
1994 Wagner J, Boerboom D, Tremblay ML. Molecular cloning and tissue-specific RNA processing of a murine receptor-type protein tyrosine phosphatase European Journal of Biochemistry. 226: 773-782. PMID 7529177 DOI: 10.1111/j.1432-1033.1994.00773.x  1
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