Zhaohui Ye, Ph.D. - Publications

Affiliations: 
2009 Johns Hopkins University, Baltimore, MD 
Area:
Cell Biology, Molecular Biology

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Chaudhari P, Tian L, Ye Z, Jang YY. Human-relevant preclinical in vitro models for studying hepatobiliary development and liver diseases using induced pluripotent stem cells. Experimental Biology and Medicine (Maywood, N.J.). 1535370219834895. PMID 30803263 DOI: 10.1177/1535370219834895  0.32
2018 Chaudhari P, Tian L, Kim A, Zhu Q, Anders R, Schwarz KB, Sharkis S, Ye Z, Jang YY. Transient c-Src suppression during endodermal commitment of human iPSCs results in abnormal profibrotic cholangiocyte-like cells. Stem Cells (Dayton, Ohio). PMID 30471152 DOI: 10.1002/stem.2950  0.32
2018 Tian L, Ye Z, Kafka K, Stewart D, Anders R, Schwarz KB, Jang YY. Biliary Atresia Relevant Human iPSCs Recapitulate Key Disease Features in a Dish. Journal of Pediatric Gastroenterology and Nutrition. PMID 30358741 DOI: 10.1097/MPG.0000000000002187  0.32
2017 Cai L, Bai H, Mahairaki V, Gao Y, He C, Wen Y, Jin YC, Wang Y, Pan RL, Qasba A, Ye Z, Cheng L. A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease. Stem Cells Translational Medicine. PMID 29164808 DOI: 10.1002/sctm.17-0066  0.56
2017 Tian L, Eldridge L, Chaudhari P, Zhang L, Anders RA, Schwarz KB, Ye Z, Jang YY. Derivation of a disease-specific human induced pluripotent stem cell line from a biliary atresia patient. Stem Cell Research. 24: 25-28. PMID 29034890 DOI: 10.1016/j.scr.2017.08.001  0.32
2017 Yuan X, Li Z, Baines AC, Gavriilaki E, Ye Z, Wen Z, Braunstein EM, Biesecker LG, Cheng L, Dong X, Brodsky RA. A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model. Plos One. 12: e0174074. PMID 28441409 DOI: 10.1371/journal.pone.0174074  0.56
2017 Liu S, Ye Z, Gao Y, He C, Williams DW, Moliterno A, Spivak J, Huang H, Cheng L. Generation of human iPSCs from an essential thrombocythemia patient carrying a V501L mutation in the MPL gene. Stem Cell Research. 18: 57-59. PMID 28395806 DOI: 10.1016/j.scr.2016.12.012  0.56
2016 Jang YY, Ye Z. Gene correction in patient-specific iPSCs for therapy development and disease modeling. Human Genetics. PMID 27256364 DOI: 10.1007/s00439-016-1691-5  0.32
2016 Tian L, Deshmukh A, Ye Z, Jang YY. Efficient and Controlled Generation of 2D and 3D Bile Duct Tissue from Human Pluripotent Stem Cell-Derived Spheroids. Stem Cell Reviews. PMID 27138846 DOI: 10.1007/s12015-016-9657-5  0.32
2016 Long H, Miller SF, Strauss C, Zhao C, Cheng L, Ye Z, Griffin K, Te R, Lee H, Chen CC, Lynch M. Antibiotic treatment enhances the genome-wide mutation rate of target cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27091991 DOI: 10.1073/pnas.1601208113  0.56
2016 Smith C, Ye Z, Cheng L. Genome Editing in Human Pluripotent Stem Cells. Cold Spring Harbor Protocols. 2016: pdb.top086819. PMID 27037079 DOI: 10.1101/pdb.top086819  0.56
2016 Smith C, Ye Z, Cheng L. A Method for Genome Editing in Human Pluripotent Stem Cells. Cold Spring Harbor Protocols. 2016: pdb.prot090217. PMID 27037073 DOI: 10.1101/pdb.prot090217  0.56
2016 Jang YY, Cai L, Ye Z. Genome editing systems in novel therapies. Discovery Medicine. 21: 57-64. PMID 26896603  0.32
2015 Chou BK, Gu H, Gao Y, Dowey SN, Wang Y, Shi J, Li Y, Ye Z, Cheng T, Cheng L. A facile method to establish human induced pluripotent stem cells from adult blood cells under feeder-free and xeno-free culture conditions: a clinically compliant approach. Stem Cells Translational Medicine. 4: 320-32. PMID 25742692 DOI: 10.5966/sctm.2014-0214  0.56
2015 Wang J, Wang N, Jin Y, Si J, Tan ZK, Du H, Cheng L, Dai X, Bai S, He H, Ye Z, Lai ML, Friend RH, Huang W. Interfacial control toward efficient and low-voltage perovskite light-emitting diodes. Advanced Materials (Deerfield Beach, Fla.). 27: 2311-6. PMID 25708283 DOI: 10.1002/adma.201405217  0.56
2015 Huang X, Wang Y, Yan W, Smith C, Ye Z, Wang J, Gao Y, Mendelsohn L, Cheng L. Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation. Stem Cells (Dayton, Ohio). 33: 1470-9. PMID 25702619 DOI: 10.1002/stem.1969  0.56
2015 Smith C, Abalde-Atristain L, He C, Brodsky BR, Braunstein EM, Chaudhari P, Jang YY, Cheng L, Ye Z. Efficient and allele-specific genome editing of disease loci in human iPSCs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 570-7. PMID 25418680 DOI: 10.1038/mt.2014.226  0.56
2014 Smith C, Gore A, Yan W, Abalde-Atristain L, Li Z, He C, Wang Y, Brodsky RA, Zhang K, Cheng L, Ye Z. Whole-genome sequencing analysis reveals high specificity of CRISPR/Cas9 and TALEN-based genome editing in human iPSCs. Cell Stem Cell. 15: 12-3. PMID 24996165 DOI: 10.1016/j.stem.2014.06.011  0.56
2014 Belet S, Fieremans N, Yuan X, Van Esch H, Verbeeck J, Ye Z, Cheng L, Brodsky BR, Hu H, Kalscheuer VM, Brodsky RA, Froyen G. Early frameshift mutation in PIGA identified in a large XLID family without neonatal lethality. Human Mutation. 35: 350-5. PMID 24357517 DOI: 10.1002/humu.22498  0.56
2014 Ye Z, Liu CF, Lanikova L, Dowey SN, He C, Huang X, Brodsky RA, Spivak JL, Prchal JT, Cheng L. Differential sensitivity to JAK inhibitory drugs by isogenic human erythroblasts and hematopoietic progenitors generated from patient-specific induced pluripotent stem cells. Stem Cells (Dayton, Ohio). 32: 269-78. PMID 24105986 DOI: 10.1002/stem.1545  0.56
2014 Huang X, Shah S, Wang J, Ye Z, Dowey SN, Tsang KM, Mendelsohn LG, Kato GJ, Kickler TS, Cheng L. Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 451-63. PMID 24002691 DOI: 10.1038/mt.2013.201  0.56
2014 Chaudhari P, Ye Z, Jang YY. Roles of reactive oxygen species in the fate of stem cells. Antioxidants & Redox Signaling. 20: 1881-90. PMID 23066813 DOI: 10.1089/ars.2012.4963  0.32
2013 Yuan X, Braunstein EM, Ye Z, Liu CF, Chen G, Zou J, Cheng L, Brodsky RA. Generation of glycosylphosphatidylinositol anchor protein-deficient blood cells from human induced pluripotent stem cells. Stem Cells Translational Medicine. 2: 819-29. PMID 24113066 DOI: 10.5966/sctm.2013-0069  0.56
2013 Ran D, Lam K, Shia WJ, Lo MC, Fan JB, Knorr DA, Ferrell PI, Ye Z, Yan M, Cheng L, Kaufman DS, Zhang DE. Response: the role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells. Blood. 121: 5252-3. PMID 23813938 DOI: 10.1182/blood-2013-04-494914  0.56
2013 Chou BK, Ye Z, Cheng L. Generation and homing of iPSC-derived hematopoietic cells in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1292-3. PMID 23812546 DOI: 10.1038/mt.2013.129  0.56
2013 Ran D, Shia WJ, Lo MC, Fan JB, Knorr DA, Ferrell PI, Ye Z, Yan M, Cheng L, Kaufman DS, Zhang DE. RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells. Blood. 121: 2882-90. PMID 23372166 DOI: 10.1182/blood-2012-08-451641  0.56
2013 Choi SM, Kim Y, Shim JS, Park JT, Wang RH, Leach SD, Liu JO, Deng C, Ye Z, Jang YY. Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells. Hepatology (Baltimore, Md.). 57: 2458-68. PMID 23325555 DOI: 10.1002/hep.26237  0.32
2012 Dowey SN, Huang X, Chou BK, Ye Z, Cheng L. Generation of integration-free human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression. Nature Protocols. 7: 2013-21. PMID 23080273 DOI: 10.1038/nprot.2012.121  0.56
2012 Ye Z, Chou BK, Cheng L. Promise and challenges of human iPSC-based hematologic disease modeling and treatment. International Journal of Hematology. 95: 601-9. PMID 22619021 DOI: 10.1007/s12185-012-1095-9  0.56
2012 Cheng L, Hansen NF, Zhao L, Du Y, Zou C, Donovan FX, Chou BK, Zhou G, Li S, Dowey SN, Ye Z, Chandrasekharappa SC, Yang H, Mullikin JC, et al. Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression. Cell Stem Cell. 10: 337-44. PMID 22385660 DOI: 10.1016/j.stem.2012.01.005  0.56
2012 Johnston JJ, Gropman AL, Sapp JC, Teer JK, Martin JM, Liu CF, Yuan X, Ye Z, Cheng L, Brodsky RA, Biesecker LG. The phenotype of a germline mutation in PIGA: the gene somatically mutated in paroxysmal nocturnal hemoglobinuria. American Journal of Human Genetics. 90: 295-300. PMID 22305531 DOI: 10.1016/j.ajhg.2011.11.031  0.56
2012 Zou C, Chou BK, Dowey SN, Tsang K, Huang X, Liu CF, Smith C, Yen J, Mali P, Zhang YA, Cheng L, Ye Z. Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines. Stem Cells and Development. 21: 2298-311. PMID 22225458 DOI: 10.1089/scd.2011.0688  0.56
2011 Ye Z, Liu CF, Jang YY. Hematopoietic cells as sources for patient-specific iPSCs and disease modeling. Cell Cycle (Georgetown, Tex.). 10: 2840-4. PMID 21857158 DOI: 10.4161/cc.10.17.17180  0.32
2011 Choi SM, Kim Y, Liu H, Chaudhari P, Ye Z, Jang YY. Liver engraftment potential of hepatic cells derived from patient-specific induced pluripotent stem cells. Cell Cycle (Georgetown, Tex.). 10: 2423-7. PMID 21750407 DOI: 10.4161/cc.10.15.16869  0.32
2011 Choi SM, Liu H, Chaudhari P, Kim Y, Cheng L, Feng J, Sharkis S, Ye Z, Jang YY. Reprogramming of EBV-immortalized B-lymphocyte cell lines into induced pluripotent Stem cells Blood. 118: 1801-1805. PMID 21628406 DOI: 10.1182/blood-2011-03-340620  0.56
2011 Jang YY, Ye Z, Cheng L. Molecular imaging and stem cell research. Molecular Imaging. 10: 111-22. PMID 21439256  0.56
2011 Broxmeyer HE, Lee MR, Hangoc G, Cooper S, Prasain N, Kim YJ, Mallett C, Ye Z, Witting S, Cornetta K, Cheng L, Yoder MC. Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood. Blood. 117: 4773-7. PMID 21393480 DOI: 10.1182/blood-2011-01-330514  0.56
2011 Wang B, Zhang YB, Zhang F, Lin H, Wang X, Wan N, Ye Z, Weng H, Zhang L, Li X, Yan J, Wang P, Wu T, Cheng L, Wang J, et al. On the origin of Tibetans and their genetic basis in adapting high-altitude environments. Plos One. 6: e17002. PMID 21386899 DOI: 10.1371/journal.pone.0017002  0.56
2011 Chou BK, Mali P, Huang X, Ye Z, Dowey SN, Resar LM, Zou C, Zhang YA, Tong J, Cheng L. Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Research. 21: 518-29. PMID 21243013 DOI: 10.1038/cr.2011.12  0.56
2010 Ye Z, Cheng L. Potential of human induced pluripotent stem cells derived from blood and other postnatal cell types. Regenerative Medicine. 5: 521-30. PMID 20632856 DOI: 10.2217/rme.10.38  0.56
2010 Liu H, Ye Z, Kim Y, Sharkis S, Jang YY. Generation of endoderm-derived human induced pluripotent stem cells from primary hepatocytes. Hepatology (Baltimore, Md.). 51: 1810-9. PMID 20432258 DOI: 10.1002/hep.23626  0.32
2010 Mali P, Ye Z, Chou BK, Yen J, Cheng L. An improved method for generating and identifying human induced pluripotent stem cells. Methods in Molecular Biology (Clifton, N.J.). 636: 191-205. PMID 20336524 DOI: 10.1007/978-1-60761-691-7_12  0.56
2010 Mali P, Chou BK, Yen J, Ye Z, Zou J, Dowey S, Brodsky RA, Ohm JE, Yu W, Baylin SB, Yusa K, Bradley A, Meyers DJ, Mukherjee C, Cole PA, et al. Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells (Dayton, Ohio). 28: 713-20. PMID 20201064 DOI: 10.1002/stem.402  0.56
2009 Ye Z, Zhan H, Mali P, Dowey S, Williams DM, Jang YY, Dang CV, Spivak JL, Moliterno AR, Cheng L. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders Blood. 114: 5473-5480. PMID 19797525 DOI: 10.1182/blood-2009-04-217406  0.56
2009 Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L. Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 5: 97-110. PMID 19540188 DOI: 10.1016/j.stem.2009.05.023  0.56
2009 Pomper MG, Hammond H, Yu X, Ye Z, Foss CA, Lin DD, Fox JJ, Cheng L. Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models. Cell Research. 19: 370-9. PMID 19114988 DOI: 10.1038/cr.2008.329  0.56
2009 Durai M, Krueger C, Ye Z, Cheng L, Mackensen A, Oelke M, Schneck JP. In vivo functional efficacy of tumor-specific T cells expanded using HLA-Ig based artificial antigen presenting cells (aAPC). Cancer Immunology, Immunotherapy : Cii. 58: 209-20. PMID 18563409 DOI: 10.1007/s00262-008-0542-1  0.56
2008 Hwang NS, Varghese S, Lee HJ, Zhang Z, Ye Z, Bae J, Cheng L, Elisseeff J. In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 20641-6. PMID 19095799 DOI: 10.1073/pnas.0809680106  0.56
2008 Hillion J, Dhara S, Sumter TF, Mukherjee M, Di Cello F, Belton A, Turkson J, Jaganathan S, Cheng L, Ye Z, Jove R, Aplan P, Lin YW, Wertzler K, Reeves R, et al. The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Cancer Research. 68: 10121-7. PMID 19074878 DOI: 10.1158/0008-5472.CAN-08-2121  0.56
2008 Mali P, Ye Z, Hommond HH, Yu X, Lin J, Chen G, Zou J, Cheng L. Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells (Dayton, Ohio). 26: 1998-2005. PMID 18511599 DOI: 10.1634/stemcells.2008-0346  0.56
2008 Yu X, Zou J, Ye Z, Hammond H, Chen G, Tokunaga A, Mali P, Li YM, Civin C, Gaiano N, Cheng L. Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment. Cell Stem Cell. 2: 461-71. PMID 18462696 DOI: 10.1016/j.stem.2008.03.001  0.56
2008 Chen G, Ye Z, Yu X, Zou J, Mali P, Brodsky RA, Cheng L. Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins. Cell Stem Cell. 2: 345-55. PMID 18397754 DOI: 10.1016/j.stem.2008.02.004  0.56
2008 Ye Z, Yu X, Cheng L. Lentiviral gene transduction of mouse and human stem cells. Methods in Molecular Biology (Clifton, N.J.). 430: 243-53. PMID 18370304 DOI: 10.1007/978-1-59745-182-6_17  0.56
2007 Baba S, Cho SY, Ye Z, Cheng L, Engles JM, Wahl RL. How reproducible is bioluminescent imaging of tumor cell growth? Single time point versus the dynamic measurement approach. Molecular Imaging. 6: 315-22. PMID 18092516 DOI: 10.2310/7290.2007.00031  0.56
2007 Li L, Piloto O, Kim KT, Ye Z, Nguyen HB, Yu X, Levis M, Cheng L, Small D. FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells. British Journal of Haematology. 137: 64-75. PMID 17359372 DOI: 10.1111/j.1365-2141.2007.06525.x  0.56
2007 Cai L, Ye Z, Zhou BY, Mali P, Zhou C, Cheng L. Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions. Cell Research. 17: 62-72. PMID 17211448 DOI: 10.1038/sj.cr.7310138  0.56
2007 Zhou BY, Ye Z, Chen G, Gao ZP, Zhang YA, Cheng L. Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Stem Cells (Dayton, Ohio). 25: 779-89. PMID 17158240 DOI: 10.1634/stemcells.2006-0128  0.56
2005 Wang K, Xue T, Tsang SY, Van Huizen R, Wong CW, Lai KW, Ye Z, Cheng L, Au KW, Zhang J, Li GR, Lau CP, Tse HF, Li RA. Electrophysiological properties of pluripotent human and mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 23: 1526-34. PMID 16091557 DOI: 10.1634/stemcells.2004-0299  0.56
2005 Dravid G, Ye Z, Hammond H, Chen G, Pyle A, Donovan P, Yu X, Cheng L. Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells (Dayton, Ohio). 23: 1489-501. PMID 16002782 DOI: 10.1634/stemcells.2005-0034  0.56
2004 Zhan X, Dravid G, Ye Z, Hammond H, Shamblott M, Gearhart J, Cheng L. Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro. Lancet (London, England). 364: 163-71. PMID 15246729 DOI: 10.1016/S0140-6736(04)16629-4  0.56
2004 Pan F, Ye Z, Cheng L, Liu JO. Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: a calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT). The Journal of Biological Chemistry. 279: 14477-80. PMID 14722108 DOI: 10.1074/jbc.C300487200  0.56
2003 Ye Z, Cheng L. Making lentiviral vectors more powerful and universal. Discovery Medicine. 3: 48-9. PMID 20704865  0.56
2003 Zhou X, Cui Y, Huang X, Yu Z, Thomas AM, Ye Z, Pardoll DM, Jaffee EM, Cheng L. Lentivirus-mediated gene transfer and expression in established human tumor antigen-specific cytotoxic T cells and primary unstimulated T cells. Human Gene Therapy. 14: 1089-105. PMID 12885348 DOI: 10.1089/104303403322124800  0.56
2003 Yu X, Zhan X, D'Costa J, Tanavde VM, Ye Z, Peng T, Malehorn MT, Yang X, Civin CI, Cheng L. Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 827-38. PMID 12788657  0.56
2003 Cheng L, Hammond H, Ye Z, Zhan X, Dravid G. Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture. Stem Cells (Dayton, Ohio). 21: 131-42. PMID 12634409 DOI: 10.1634/stemcells.21-2-131  0.56
2002 Cui Y, Golob J, Kelleher E, Ye Z, Pardoll D, Cheng L. Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells. Blood. 99: 399-408. PMID 11781219 DOI: 10.1182/blood.V99.2.399  0.56
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