Kin L. Fok, Ph.D. - Publications

Affiliations: 
2010 The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Oncology, Cell Biology, General Biology

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Li X, Yuan C, Shi J, Kang H, Chen Y, Duan Y, Jin J, Cheung LP, Li TC, Liu Y, Cui Y, Ruan YC, Jiang X, Cai Z, Chan HC, ... ... Fok KL, et al. β-Defensin 19/119 mediates sperm chemotaxis and is associated with idiopathic infertility. Cell Reports. Medicine. 100825. PMID 36513070 DOI: 10.1016/j.xcrm.2022.100825  0.424
2020 Chen Z, Li X, Jin J, Zhou W, Chen J, Fok KL. Connective tissue growth factor mediates mouse spermatogonial migration associated with differentiation. Biochimica Et Biophysica Acta. Molecular Cell Research. 118708. PMID 32240712 DOI: 10.1016/J.Bbamcr.2020.118708  0.358
2019 Wong TW, Kan CD, Chiu WT, Fok KL, Ruan YC, Jiang X, Chen J, Kao CC, Chen IY, Lin HC, Chou CH, Lin CW, Yu CK, Tsao S, Lee YP, et al. Progenitor Cells Derived from Drain Waste Product of Open-Heart Surgery in Children. Journal of Clinical Medicine. 8. PMID 31336927 DOI: 10.3390/Jcm8071028  0.451
2018 Wang C, Zhang J, Fok KL, Tsang LL, Ye M, Liu J, Li F, Zhao AZ, Chan HC, Chen H. CD147 induces epithelial-to-mesenchymal transition by disassembling CAS/E-cadherin/β-catenin complex in human endometriosis. The American Journal of Pathology. PMID 29630856 DOI: 10.1016/J.Ajpath.2018.03.004  0.471
2018 Li X, Fok KL, Guo J, Wang Y, Liu Z, Chen Z, Wang C, Ruan YC, Yu SS, Zhao H, Wu J, Jiang X, Chan HC. Retinoic acid promotes stem cell differentiation and embryonic development by transcriptionally activating CFTR. Biochimica Et Biophysica Acta. PMID 29326073 DOI: 10.1016/J.Bbamcr.2018.01.005  0.479
2017 Bose R, Sheng K, Moawad AR, Manku G, O'Flaherty C, Taketo T, Culty M, Fok KL, Wing SS. Ubiquitin Ligase Huwe1 Modulates Spermatogenesis by Regulating Spermatogonial Differentiation and Entry into Meiosis. Scientific Reports. 7: 17759. PMID 29259204 DOI: 10.1038/S41598-017-17902-0  0.352
2017 Diao R, Wang T, Fok KL, Li X, Ruan Y, Yu MK, Cheng Y, Chen Y, Chen H, Mou L, Cai X, Wang Y, Cai Z, Zeng X, Chan HC. CCR6 is required for ligand-induced CatSper activation in human sperm. Oncotarget. 8: 91445-91458. PMID 29207656 DOI: 10.18632/Oncotarget.20651  0.483
2017 Fok KL, Bose R, Sheng K, Chang CW, Katz-Egorov M, Culty M, Su S, Yang M, Ruan YC, Chan HC, Iavarone A, Lasorella A, Cencic R, Pelletier J, Nagano M, et al. Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response. Endocrinology. PMID 28938460 DOI: 10.1210/En.2017-00396  0.496
2016 Wang C, Fok KL, Cai Z, Chen H, Chan HC. CD147 regulates extrinsic apoptosis in spermatocytes by modulating NFκB signaling pathways. Oncotarget. PMID 27902973 DOI: 10.18632/Oncotarget.13624  0.487
2016 Lu YC, Yang J, Fok KL, Ye YH, Jin L, Chen ZY, Zhang XM, Huang HF, Chan HC. Involvement of Cl(-)/HCO3(-) exchanger SLC26A3 and SLC26A6 in preimplantation embryo cleavage. Scientific Reports. 6: 28402. PMID 27346053 DOI: 10.1038/Srep28402  0.489
2014 Diao R, Fok KL, Chen H, Yu MK, Duan Y, Chung CM, Li Z, Wu H, Li Z, Zhang H, Ji Z, Zhen W, Ng CF, Gui Y, Cai Z, et al. Deficient human β-defensin 1 underlies male infertility associated with poor sperm motility and genital tract infection. Science Translational Medicine. 6: 249ra108. PMID 25122636 DOI: 10.1126/Scitranslmed.3009071  0.487
2014 Guo JH, Chen H, Ruan YC, Zhang XL, Zhang XH, Fok KL, Tsang LL, Yu MK, Huang WQ, Sun X, Chung YW, Jiang X, Sohma Y, Chan HC. Glucose-induced electrical activities and insulin secretion in pancreatic islet β-cells are modulated by CFTR. Nature Communications. 5: 4420. PMID 25025956 DOI: 10.1038/Ncomms5420  0.461
2014 Fok KL, Chen H, Ruan YC, Chan HC. Novel regulators of spermatogenesis. Seminars in Cell & Developmental Biology. 29: 31-42. PMID 24594193 DOI: 10.1016/J.Semcdb.2014.02.008  0.48
2013 Diao R, Fok KL, Zhao L, Chen H, Tang H, Chen J, Zheng A, Zhang X, Gui Y, Chan HC, Cai Z. Decreased expression of cystic fibrosis transmembrane conductance regulator impairs sperm quality in aged men. Reproduction (Cambridge, England). 146: 637-45. PMID 24077955 DOI: 10.1530/REP-13-0146  0.407
2013 Zhang JT, Jiang XH, Xie C, Cheng H, Da Dong J, Wang Y, Fok KL, Zhang XH, Sun TT, Tsang LL, Chen H, Sun XJ, Chung YW, Cai ZM, Jiang WG, et al. Downregulation of CFTR promotes epithelial-to-mesenchymal transition and is associated with poor prognosis of breast cancer. Biochimica Et Biophysica Acta. 1833: 2961-9. PMID 23916755 DOI: 10.1016/J.Bbamcr.2013.07.021  0.493
2013 Xie C, Jiang XH, Zhang JT, Sun TT, Dong JD, Sanders AJ, Diao RY, Wang Y, Fok KL, Tsang LL, Yu MK, Zhang XH, Chung YW, Ye L, Zhao MY, et al. CFTR suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer. Oncogene. 32: 2282-91, 2291.e1-7. PMID 22797075 DOI: 10.1038/Onc.2012.251  0.401
2012 Zhang XH, Ma ZG, Rowlands DK, Gou YL, Fok KL, Wong HY, Yu MK, Tsang LL, Mu L, Chen L, Yung WH, Chung YW, Zhang BL, Zhao H, Chan HC. Flavonoid Myricetin Modulates GABA(A) Receptor Activity through Activation of Ca(2+) Channels and CaMK-II Pathway. Evidence-Based Complementary and Alternative Medicine : Ecam. 2012: 758097. PMID 23258999 DOI: 10.1155/2012/758097  0.449
2012 Chen J, Fok KL, Chen H, Zhang XH, Xu WM, Chan HC. Cryptorchidism-induced CFTR down-regulation results in disruption of testicular tight junctions through up-regulation of NF-κB/COX-2/PGE2. Human Reproduction (Oxford, England). 27: 2585-97. PMID 22777528 DOI: 10.1093/Humrep/Des254  0.487
2012 Ruan YC, Guo JH, Liu X, Zhang R, Tsang LL, Dong JD, Chen H, Yu MK, Jiang X, Zhang XH, Fok KL, Chung YW, Huang H, Zhou WL, Chan HC. Activation of the epithelial Na+ channel triggers prostaglandin Eâ‚‚ release and production required for embryo implantation. Nature Medicine. 18: 1112-7. PMID 22729284 DOI: 10.1038/Nm.2771  0.462
2012 Lu YC, Chen H, Fok KL, Tsang LL, Yu MK, Zhang XH, Chen J, Jiang X, Chung YW, Ma AC, Leung AY, Huang HF, Chan HC. CFTR mediates bicarbonate-dependent activation of miR-125b in preimplantation embryo development. Cell Research. 22: 1453-66. PMID 22664907 DOI: 10.1038/Cr.2012.88  0.455
2012 Wu W, Song W, Li S, Ouyang S, Fok KL, Diao R, Miao S, Chan HC, Wang L. Regulation of apoptosis by Bat3-enhanced YWK-II/APLP2 protein stability. Journal of Cell Science. 125: 4219-29. PMID 22641691 DOI: 10.1242/Jcs.086553  0.479
2012 Tang XX, Fok KL, Chen H, Chan KS, Tsang LL, Rowlands DK, Zhang XH, Dong JD, Ruan YC, Jiang X, Yu SS, Chung YW, Chan HC. Lymphocyte CFTR promotes epithelial bicarbonate secretion for bacterial killing. Journal of Cellular Physiology. 227: 3887-94. PMID 22552906 DOI: 10.1002/Jcp.24101  0.516
2012 Chen H, Fok KL, Jiang X, Jiang J, Chen Z, Gui Y, Chan HC, Cai Z. CD147 regulates apoptosis in mouse spermatocytes but not spermatogonia. Human Reproduction (Oxford, England). 27: 1568-76. PMID 22451502 DOI: 10.1093/Humrep/Des050  0.479
2012 Fu J, Wang Y, Fok KL, Yang D, Qiu Y, Chan HC, Koide SS, Miao S, Wang L. Anti-ACTL7a antibodies: a cause of infertility. Fertility and Sterility. 97: 1226-33.e1-8. PMID 22386842 DOI: 10.1016/J.Fertnstert.2012.02.023  0.405
2012 Chen H, Guo JH, Lu YC, Ding GL, Yu MK, Tsang LL, Fok KL, Liu XM, Zhang XH, Chung YW, Huang P, Huang H, Chan HC. Impaired CFTR-dependent amplification of FSH-stimulated estrogen production in cystic fibrosis and PCOS. The Journal of Clinical Endocrinology and Metabolism. 97: 923-32. PMID 22170719 DOI: 10.1210/Jc.2011-1363  0.474
2011 Liu Y, Jiang X, Zhang X, Chen R, Sun T, Fok KL, Dong J, Tsang LL, Yi S, Ruan Y, Guo J, Yu MK, Tian Y, Chung YW, Yang M, et al. Dedifferentiation-reprogrammed mesenchymal stem cells with improved therapeutic potential. Stem Cells (Dayton, Ohio). 29: 2077-89. PMID 22052697 DOI: 10.1002/Stem.764  0.46
2011 Xu WM, Chen J, Chen H, Diao RY, Fok KL, Dong JD, Sun TT, Chen WY, Yu MK, Zhang XH, Tsang LL, Lau A, Shi QX, Shi QH, Huang PB, et al. Defective CFTR-dependent CREB activation results in impaired spermatogenesis and azoospermia. Plos One. 6: e19120. PMID 21625623 DOI: 10.1371/Journal.Pone.0019120  0.631
2011 Chen H, Fok KL, Yu S, Jiang J, Chen Z, Gui Y, Cai Z, Chan HC. CD147 is required for matrix metalloproteinases-2 production and germ cell migration during spermatogenesis. Molecular Human Reproduction. 17: 405-14. PMID 21343160 DOI: 10.1093/Molehr/Gar013  0.468
2010 Ajonuma LC, Fok KL, Ho LS, Chan PK, Chow PH, Tsang LL, Wong CH, Chen J, Li S, Rowlands DK, Chung YW, Chan HC. CFTR is required for cellular entry and internalization of Chlamydia trachomatis. Cell Biology International. 34: 593-600. PMID 20178459 DOI: 10.1042/Cbi20090227  0.504
2010 Xu W, Zhang X, Chen W, Fok KL, Rowlands DK, Chui YL, Chan HC. Immunization with Bin1b decreases sperm motility with compromised fertility in rats. Fertility and Sterility. 93: 952-958.e1. PMID 19135192 DOI: 10.1016/J.Fertnstert.2008.10.066  0.547
2010 Chen H, Fok KL, Gui Y, Cai Z, Chan HC. Co-localization of CD147 and matrix metalloproteinases and its implication for spermatogenesis during mouse testis development Cell Biology International. 34: S8-S8. DOI: 10.1042/Cbi034S008B  0.443
2009 Yin L, Chung CM, Huo R, Liu H, Zhou C, Xu W, Zhu H, Zhang J, Shi Q, Wong HY, Chen J, Lu Y, Bi Y, Zhao C, Du Y, ... ... Fok KL, et al. A sperm GPI-anchored protein elicits sperm-cumulus cross-talk leading to the acrosome reaction. Cellular and Molecular Life Sciences : Cmls. 66: 900-8. PMID 19153666 DOI: 10.1007/S00018-009-8482-2  0.587
2009 Yin LL, Chung CM, Chen J, Fok KL, Ng CP, Jia RR, Ren X, Zhou J, Zhang T, Zhao XH, Lin M, Zhu H, Zhang XH, Tsang LL, Bi Y, et al. A suppressor of multiple extracellular matrix-degrading proteases and cancer metastasis. Journal of Cellular and Molecular Medicine. 13: 4034-41. PMID 19017363 DOI: 10.1111/J.1582-4934.2008.00576.X  0.471
2008 Ajonuma LC, Chan PK, Ng EH, Fok KL, Wong CH, Tsang LL, Tang XX, Ho LS, Lau MC, Chung CM, He Q, Huang HY, Yang DZ, Rowlands DK, Chung YW, et al. Involvement of cystic fibrosis transmembrane conductance regulator (CFTR) in the pathogenesis of hydrosalpinx induced by Chlamydia trachomatis infection. The Journal of Obstetrics and Gynaecology Research. 34: 923-30. PMID 19012687 DOI: 10.1111/J.1447-0756.2008.00826.X  0.496
2008 Wang Y, Guan X, Fok KL, Li S, Zhang X, Miao S, Zong S, Koide SS, Chan HC, Wang L. A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis. Cellular and Molecular Life Sciences : Cmls. 65: 3822-9. PMID 18953687 DOI: 10.1007/s00018-008-8452-0  0.393
2008 Ajonuma LC, He Q, Sheung Chan PK, Yu Ng EH, Fok KL, Yan Wong CH, Tsang LL, Ho LS, Lau MC, Huang HY, Yang DZ, Rowlands DK, Tang XX, Zhang XH, Chung YW, et al. Involvement of cystic fibrosis transmembrane conductance regulator in infection-induced edema. Cell Biology International. 32: 801-6. PMID 18462959 DOI: 10.1016/J.Cellbi.2008.03.010  0.479
2008 Zhang XH, Rowlands DK, Ma ZG, Gou YL, Tsang LL, Wong HY, Fok KL, Chung YW, Mu L, Chan HC. Herbal extract ECBRC-AG and its active intgredient reduces HPA axis funtion by inhibiting PVN neurons activity through T-type calcium channels Cell Biology International. 32: S66-S67. DOI: 10.1016/J.Cellbi.2008.01.283  0.421
2008 Xu WM, Chen WY, Dong HS, Fok KL, Zhou CX, Zhu H, Yan Wong CH, Chan HC. The functional role of CFTR in spermatogenesis Cell Biology International. 32: S65-S65. DOI: 10.1016/J.Cellbi.2008.01.278  0.453
2007 Yin X, Ouyang S, Xu W, Zhang X, Fok KL, Wong HY, Zhang J, Qiu X, Miao S, Chan HC, Wang L. YWK-II protein as a novel G(o)-coupled receptor for Müllerian inhibiting substance in cell survival. Journal of Cell Science. 120: 1521-8. PMID 17452623 DOI: 10.1242/Jcs.001230  0.488
2006 Shu C, Li TY, Tsang LL, Fok KL, Lo PS, Zhu JX, Ho LS, Chung YW, Chan HC. Differentiation of adult rat bone marrow stem cells into epithelial progenitor cells in culture. Cell Biology International. 30: 823-8. PMID 16877014 DOI: 10.1016/J.Cellbi.2006.06.004  0.488
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