Lea M. Starita, Ph.D. - Publications

Affiliations: 
2005 Harvard University, Cambridge, MA, United States 
Area:
Molecular Biology

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Starita LM, Islam MM, Banerjee T, Adamovich AI, Gullingsrud J, Fields S, Shendure J, Parvin JD. A Multiplex Homology-Directed DNA Repair Assay Reveals the Impact of More Than 1,000 BRCA1 Missense Substitution Variants on Protein Function. American Journal of Human Genetics. PMID 30219179 DOI: 10.1016/j.ajhg.2018.07.016  0.68
2015 Lee C, Banerjee T, Gillespie J, Ceravolo A, Parvinsmith MR, Starita LM, Fields S, Toland AE, Parvin JD. Functional Analysis of BARD1 Missense Variants in Homology-Directed Repair of DNA Double Strand Breaks. Human Mutation. 36: 1205-14. PMID 26350354 DOI: 10.1002/humu.22902  0.44
2015 Starita LM, Fields S. Deep Mutational Scanning: A Highly Parallel Method to Measure the Effects of Mutation on Protein Function. Cold Spring Harbor Protocols. 2015: 711-4. PMID 26240414 DOI: 10.1101/pdb.top077503  0.44
2015 Starita LM, Fields S. Deep Mutational Scanning: Calculating Enrichment Scores for Protein Variants from DNA Sequencing Output Files. Cold Spring Harbor Protocols. 2015: 781-3. PMID 26240406 DOI: 10.1101/pdb.prot085233  0.44
2015 Starita LM, Fields S. Deep Mutational Scanning: Library Construction, Functional Selection, and High-Throughput Sequencing. Cold Spring Harbor Protocols. 2015: 777-80. PMID 26240405 DOI: 10.1101/pdb.prot085225  0.44
2015 Starita LM, Young DL, Islam M, Kitzman JO, Gullingsrud J, Hause RJ, Fowler DM, Parvin JD, Shendure J, Fields S. Massively Parallel Functional Analysis of BRCA1 RING Domain Variants. Genetics. 200: 413-22. PMID 25823446 DOI: 10.1534/genetics.115.175802  0.44
2013 Starita LM, Pruneda JN, Lo RS, Fowler DM, Kim HJ, Hiatt JB, Shendure J, Brzovic PS, Fields S, Klevit RE. Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: E1263-72. PMID 23509263 DOI: 10.1073/pnas.1303309110  0.44
2012 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S. Sites of ubiquitin attachment in Saccharomyces cerevisiae. Proteomics. 12: 236-40. PMID 22106047 DOI: 10.1002/pmic.201100166  0.44
2007 Pujana MA, Han JD, Starita LM, Stevens KN, Tewari M, Ahn JS, Rennert G, Moreno V, Kirchhoff T, Gold B, Assmann V, Elshamy WM, Rual JF, Levine D, Rozek LS, et al. Network modeling links breast cancer susceptibility and centrosome dysfunction. Nature Genetics. 39: 1338-49. PMID 17922014 DOI: 10.1038/ng.2007.2  0.44
2006 Ozturk SB, Vishnu MR, Olarewaju O, Starita LM, Masison DC, Kinzy TG. Unique classes of mutations in the Saccharomyces cerevisiae G-protein translation elongation factor 1A suppress the requirement for guanine nucleotide exchange. Genetics. 174: 651-63. PMID 16951075 DOI: 10.1534/genetics.106.059899  0.44
2006 Sankaran S, Starita LM, Simons AM, Parvin JD. Identification of domains of BRCA1 critical for the ubiquitin-dependent inhibition of centrosome function. Cancer Research. 66: 4100-7. PMID 16618730 DOI: 10.1158/0008-5472.CAN-05-4430  0.68
2006 Simons AM, Horwitz AA, Starita LM, Griffin K, Williams RS, Glover JN, Parvin JD. BRCA1 DNA-binding activity is stimulated by BARD1. Cancer Research. 66: 2012-8. PMID 16489000 DOI: 10.1158/0008-5472.CAN-05-3296  0.68
2006 Starita LM, Parvin JD. Substrates of the BRCA1-dependent ubiquitin ligase. Cancer Biology & Therapy. 5: 137-41. PMID 16479151  0.68
2005 Sankaran S, Starita LM, Groen AC, Ko MJ, Parvin JD. Centrosomal microtubule nucleation activity is inhibited by BRCA1-dependent ubiquitination. Molecular and Cellular Biology. 25: 8656-68. PMID 16166645 DOI: 10.1128/MCB.25.19.8656-8668.2005  0.44
2005 Starita LM, Horwitz AA, Keogh MC, Ishioka C, Parvin JD, Chiba N. BRCA1/BARD1 ubiquitinate phosphorylated RNA polymerase II. The Journal of Biological Chemistry. 280: 24498-505. PMID 15886201 DOI: 10.1074/jbc.M414020200  0.44
2004 Starita LM, Machida Y, Sankaran S, Elias JE, Griffin K, Schlegel BP, Gygi SP, Parvin JD. BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number. Molecular and Cellular Biology. 24: 8457-66. PMID 15367667 DOI: 10.1128/MCB.24.19.8457-8466.2004  0.68
2003 Starita LM, Parvin JD. The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair. Current Opinion in Cell Biology. 15: 345-50. PMID 12787778  0.68
2003 Schlegel BP, Starita LM, Parvin JD. Overexpression of a protein fragment of RNA helicase A causes inhibition of endogenous BRCA1 function and defects in ploidy and cytokinesis in mammary epithelial cells. Oncogene. 22: 983-91. PMID 12592385 DOI: 10.1038/sj.onc.1206195  0.68
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