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Andrea Bredemeyer, Ph.D. - Publications

Affiliations: 
2006 Washington University, Saint Louis, St. Louis, MO 
Area:
Immunology, Cell Biology, Molecular Biology
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Chen BR, Quinet A, Byrum AK, Jackson J, Berti M, Thangavel S, Bredemeyer AL, Hindi I, Mosammaparast N, Tyler JK, Vindigni A, Sleckman BP. XLF and H2AX function in series to promote replication fork stability. The Journal of Cell Biology. PMID 31123184 DOI: 10.1083/jcb.201808134  0.736
2018 Hung PJ, Johnson B, Chen BR, Byrum AK, Bredemeyer AL, Yewdell WT, Johnson TE, Lee BJ, Deivasigamani S, Hindi I, Amatya P, Gross ML, Paull TT, Pisapia DJ, Chaudhuri J, et al. MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining. Molecular Cell. PMID 30017584 DOI: 10.1016/J.Molcel.2018.06.018  0.694
2017 Bredemeyer AL, Edwards BS, Haynes MK, Morales AJ, Wang Y, Ursu O, Waller A, Sklar LA, Sleckman BP. High-Throughput Screening Approach for Identifying Compounds That Inhibit Nonhomologous End Joining. Slas Discovery : Advancing Life Sciences R & D. 2472555217746324. PMID 29232168 DOI: 10.1177/2472555217746324  0.609
2016 Hung PJ, Chen BR, George R, Liberman C, Morales AJ, Colon-Ortiz P, Tyler JK, Sleckman BP, Bredemeyer AL. Deficiency of XLF and PAXX Prevents DNA Double-Strand Break Repair by Non-homologous End Joining in Lymphocytes. Cell Cycle (Georgetown, Tex.). 0. PMID 27830975 DOI: 10.1080/15384101.2016.1253640  0.733
2016 Brauer PM, Pessach IM, Clarke E, Rowe JH, Ott de Bruin L, Lee YN, Dominguez-Brauer C, Comeau AM, Awong G, Felgentreff K, Zhang YH, Bredemeyer A, Al-Herz W, Du L, Ververs F, et al. Modeling altered T-cell development with human induced pluripotent stem cells from patients with RAG1 mutations and distinct immunological phenotypes. Blood. PMID 27301863 DOI: 10.1182/Blood-2015-10-676304  0.563
2015 Bredemeyer AL, Sleckman BP. DNA damage responses: beyond double-strand break repair. Current Biology : Cb. 25: R45-6. PMID 25562302 DOI: 10.1016/j.cub.2014.11.024  0.739
2014 Dorsett Y, Zhou Y, Tubbs AT, Chen BR, Purman C, Lee BS, George R, Bredemeyer AL, Zhao JY, Sodergen E, Weinstock GM, Han ND, Reyes A, Oltz EM, Dorsett D, et al. HCoDES reveals chromosomal DNA end structures with single-nucleotide resolution. Molecular Cell. 56: 808-18. PMID 25435138 DOI: 10.1016/J.Molcel.2014.10.024  0.731
2014 Tubbs AT, Dorsett Y, Chan E, Helmink B, Lee BS, Hung P, George R, Bredemeyer AL, Mittal A, Pappu RV, Chowdhury D, Mosammaparast N, Krangel MS, Sleckman BP. KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G₁-phase lymphocytes. Molecular and Cellular Biology. 34: 2811-21. PMID 24842905 DOI: 10.1128/Mcb.00441-14  0.815
2014 Dose M, Emmanuel AO, Chaumeil J, Zhang J, Sun T, Germar K, Aghajani K, Davis EM, Keerthivasan S, Bredemeyer AL, Sleckman BP, Rosen ST, Skok JA, Le Beau MM, Georgopoulos K, et al. β-Catenin induces T-cell transformation by promoting genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 111: 391-6. PMID 24371308 DOI: 10.1073/Pnas.1315752111  0.663
2013 Lee BS, Gapud EJ, Zhang S, Dorsett Y, Bredemeyer A, George R, Callen E, Daniel JA, Osipovich O, Oltz EM, Bassing CH, Nussenzweig A, Lees-Miller S, Hammel M, Chen BP, et al. Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination. Molecular and Cellular Biology. 33: 3568-79. PMID 23836881 DOI: 10.1128/Mcb.00308-13  0.822
2012 Solimini NL, Xu Q, Mermel CH, Liang AC, Schlabach MR, Luo J, Burrows AE, Anselmo AN, Bredemeyer AL, Li MZ, Beroukhim R, Meyerson M, Elledge SJ. Recurrent hemizygous deletions in cancers may optimize proliferative potential. Science (New York, N.Y.). 337: 104-9. PMID 22628553 DOI: 10.1126/Science.1219580  0.735
2011 Gapud EJ, Dorsett Y, Yin B, Callen E, Bredemeyer A, Mahowald GK, Omi KQ, Walker LM, Bednarski JJ, McKinnon PJ, Bassing CH, Nussenzweig A, Sleckman BP. Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 2022-7. PMID 21245316 DOI: 10.1073/Pnas.1013295108  0.79
2010 O'Connell BC, Adamson B, Lydeard JR, Sowa ME, Ciccia A, Bredemeyer AL, Schlabach M, Gygi SP, Elledge SJ, Harper J. Wade JW. A Genome-wide Camptothecin Sensitivity Screen Identifies a Mammalian MMS22L-NFKBIL2 Complex Required for Genomic Stability Molecular Cell. 40: 645-657. PMID 21055985 DOI: 10.1016/J.Molcel.2010.10.022  0.596
2010 Reavie L, Della Gatta G, Crusio K, Aranda-Orgilles B, Buckley SM, Thompson B, Lee E, Gao J, Bredemeyer AL, Helmink BA, Zavadil J, Sleckman BP, Palomero T, Ferrando A, Aifantis I. Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase-substrate complex. Nature Immunology. 11: 207-15. PMID 20081848 DOI: 10.1038/Ni.1839  0.705
2009 Yin B, Savic V, Juntilla MM, Bredemeyer AL, Yang-Iott KS, Helmink BA, Koretzky GA, Sleckman BP, Bassing CH. Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination. The Journal of Experimental Medicine. 206: 2625-39. PMID 19887394 DOI: 10.1084/Jem.20091320  0.81
2009 Mahowald GK, Baron JM, Mahowald MA, Kulkarni S, Bredemeyer AL, Bassing CH, Sleckman BP. Aberrantly resolved RAG-mediated DNA breaks in Atm-deficient lymphocytes target chromosomal breakpoints in cis. Proceedings of the National Academy of Sciences of the United States of America. 106: 18339-44. PMID 19820166 DOI: 10.1073/Pnas.0902545106  0.785
2009 Ciccia A, Bredemeyer AL, Sowa ME, Terret ME, Jallepalli PV, Harper JW, Elledge SJ. The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart Genes and Development. 23: 2415-2425. PMID 19793862 DOI: 10.1101/Gad.1832309  0.672
2009 Savic V, Yin B, Maas NL, Bredemeyer AL, Carpenter AC, Helmink BA, Yang-Iott KS, Sleckman BP, Bassing CH. Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin. Molecular Cell. 34: 298-310. PMID 19450528 DOI: 10.1016/J.Molcel.2009.04.012  0.786
2009 Dose M, Sleckman BP, Han J, Bredemeyer AL, Bendelac A, Gounari F. Intrathymic proliferation wave essential for Valpha14+ natural killer T cell development depends on c-Myc. Proceedings of the National Academy of Sciences of the United States of America. 106: 8641-6. PMID 19423665 DOI: 10.1073/Pnas.0812255106  0.529
2009 Helmink BA, Bredemeyer AL, Lee BS, Huang CY, Sharma GG, Walker LM, Bednarski JJ, Lee WL, Pandita TK, Bassing CH, Sleckman BP. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks. The Journal of Experimental Medicine. 206: 669-79. PMID 19221393 DOI: 10.1084/Jem.20081326  0.827
2008 Bredemeyer AL, Helmink BA, Innes CL, Calderon B, McGinnis LM, Mahowald GK, Gapud EJ, Walker LM, Collins JB, Weaver BK, Mandik-Nayak L, Schreiber RD, Allen PM, May MJ, Paules RS, et al. DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes. Nature. 456: 819-23. PMID 18849970 DOI: 10.1038/Nature07392  0.768
2008 Bredemeyer AL, Huang CY, Walker LM, Bassing CH, Sleckman BP. Aberrant V(D)J recombination in ataxia telangiectasia mutated-deficient lymphocytes is dependent on nonhomologous DNA end joining. Journal of Immunology (Baltimore, Md. : 1950). 181: 2620-5. PMID 18684952 DOI: 10.4049/Jimmunol.181.4.2620  0.69
2008 Huang CY, Bredemeyer AL, Walker LM, Bassing CH, Sleckman BP. Dynamic regulation of c-Myc proto-oncogene expression during lymphocyte development revealed by a GFP-c-Myc knock-in mouse. European Journal of Immunology. 38: 342-9. PMID 18196519 DOI: 10.1002/Eji.200737972  0.527
2007 Bredemeyer AL, Sleckman BP. SWI-SNF: promoter of accessibility. Nature Immunology. 8: 795-6. PMID 17641658 DOI: 10.1038/ni0807-795  0.481
2007 Callén E, Jankovic M, Difilippantonio S, Daniel JA, Chen HT, Celeste A, Pellegrini M, McBride K, Wangsa D, Bredemeyer AL, Sleckman BP, Ried T, Nussenzweig M, Nussenzweig A. ATM Prevents the Persistence and Propagation of Chromosome Breaks in Lymphocytes Cell. 130: 63-75. PMID 17599403 DOI: 10.1016/J.Cell.2007.06.016  0.702
2006 Bredemeyer AL, Sharma GG, Huang CY, Helmink BA, Walker LM, Khor KC, Nuskey B, Sullivan KE, Pandita TK, Bassing CH, Sleckman BP. ATM stabilizes DNA double-strand-break complexes during V(D)J recombination. Nature. 442: 466-70. PMID 16799570 DOI: 10.1038/Nature04866  0.832
2006 Khor B, Bredemeyer AL, Huang CY, Turnbull IR, Evans R, Maggi LB, White JM, Walker LM, Carnes K, Hess RA, Sleckman BP. Proteasome activator PA200 is required for normal spermatogenesis Molecular and Cellular Biology. 26: 2999-3007. PMID 16581775 DOI: 10.1128/Mcb.26.8.2999-3007.2006  0.795
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