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Jonathan K. Alder, Ph.D. - Publications

Affiliations: 
2008 Johns Hopkins University, Baltimore, MD 
Area:
Molecular Biology, Cell Biology, Immunology
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Sullivan DI, Jiang M, Hinchie AM, Roth MG, Bahudhanapati H, Nouraie M, Liu J, McDyer JF, Mallampalli RK, Zhang Y, Kass DJ, Finkel T, Alder JK. Transcriptional and Proteomic Characterization of Telomere-Induced Senescence in a Human Alveolar Epithelial Cell Line. Frontiers in Medicine. 8: 600626. PMID 33634147 DOI: 10.3389/fmed.2021.600626  0.318
2020 Li X, Kim SE, Chen TY, Wang J, Yang X, Tabib T, Tan J, Guo B, Fung S, Zhao J, Sembrat J, Rojas M, Shiva S, Lafyatis R, St Croix C, ... Alder JK, et al. Toll interacting protein protects bronchial epithelial cells from bleomycin-induced apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32596871 DOI: 10.1096/Fj.201902636Rr  0.388
2020 Jiang M, Roth MG, Chun-On P, Sullivan DI, Alder JK. Phenotypic Diversity Caused by Differential Expression of -Cre Transgenic Alleles. American Journal of Respiratory Cell and Molecular Biology. PMID 32208105 DOI: 10.1165/Rcmb.2019-0416Ma  0.367
2019 Zhang Y, Jiang M, Nouraie M, Roth MG, Tabib T, Winters S, Chen X, Sembrat J, Chu Y, Cardenes N, Tuder RM, Herzog EL, Ryu C, Rojas M, Lafyatis R, ... ... Alder JK, et al. GDF15 is an epithelial-derived biomarker of idiopathic pulmonary fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 31432710 DOI: 10.1152/Ajplung.00062.2019  0.401
2019 Hamsanathan S, Alder JK, Sellares J, Rojas M, Gurkar AU, Mora AL. Cellular Senescence: The Trojan Horse in Chronic Lung Diseases. American Journal of Respiratory Cell and Molecular Biology. PMID 30965013 DOI: 10.1165/Rcmb.2018-0410Tr  0.356
2018 Wagner CL, Hanumanthu VS, Talbot CC, Abraham RS, Hamm D, Gable DL, Kanakry CG, Applegate CD, Siliciano J, Jackson JB, Desiderio SV, Alder JK, Luznik L, Armanios M. Short telomere syndromes cause a primary T cell immunodeficiency. The Journal of Clinical Investigation. PMID 30179220 DOI: 10.1172/Jci120216  0.356
2018 Alder JK, Hanumanthu VS, Strong MA, DeZern AE, Stanley SE, Takemoto CM, Danilova L, Applegate CD, Bolton SG, Mohr DW, Brodsky RA, Casella JF, Greider CW, Jackson JB, Armanios M. Diagnostic utility of telomere length testing in a hospital-based setting. Proceedings of the National Academy of Sciences of the United States of America. PMID 29463756 DOI: 10.1073/Pnas.1720427115  0.327
2017 Strock SB, Alder JK, Kass DJ. From Bad to Worse: When Lung Cancer Complicates Idiopathic Pulmonary Fibrosis. The Journal of Pathology. PMID 29282737 DOI: 10.1002/Path.5027  0.301
2016 Stanley SE, Gable DL, Wagner CL, Carlile TM, Hanumanthu VS, Podlevsky JD, Khalil SE, DeZern AE, Rojas-Duran MF, Applegate CD, Alder JK, Parry EM, Gilbert WV, Armanios M. Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema. Science Translational Medicine. 8: 351ra107. PMID 27510903 DOI: 10.1126/Scitranslmed.Aaf7837  0.34
2015 Alder JK, Barkauskas CE, Limjunyawong N, Stanley SE, Kembou F, Tuder RM, Hogan BL, Mitzner W, Armanios M. Telomere dysfunction causes alveolar stem cell failure. Proceedings of the National Academy of Sciences of the United States of America. 112: 5099-104. PMID 25840590 DOI: 10.1073/Pnas.1504780112  0.421
2015 Stanley SE, Chen JJ, Podlevsky JD, Alder JK, Hansel NN, Mathias RA, Qi X, Rafaels NM, Wise RA, Silverman EK, Barnes KC, Armanios M. Telomerase mutations in smokers with severe emphysema. The Journal of Clinical Investigation. 125: 563-70. PMID 25562321 DOI: 10.1172/Jci78554  0.318
2015 Alder JK, Stanley SE, Wagner CL, Hamilton M, Hanumanthu VS, Armanios M. Exome Sequencing Identifies Mutant TINF2 in a Family With Pulmonary Fibrosis. Chest. 147: 1361-8. PMID 25539146 DOI: 10.1378/Chest.14-1947  0.326
2013 Alder JK, Parry EM, Yegnasubramanian S, Wagner CL, Lieblich LM, Auerbach R, Auerbach AD, Wheelan SJ, Armanios M. Telomere phenotypes in females with heterozygous mutations in the dyskeratosis congenita 1 (DKC1) gene. Human Mutation. 34: 1481-5. PMID 23946118 DOI: 10.1002/Humu.22397  0.327
2011 Alder JK, Guo N, Kembou F, Parry EM, Anderson CJ, Gorgy AI, Walsh MF, Sussan T, Biswal S, Mitzner W, Tuder RM, Armanios M. Telomere length is a determinant of emphysema susceptibility. American Journal of Respiratory and Critical Care Medicine. 184: 904-12. PMID 21757622 DOI: 10.1164/Rccm.201103-0520Oc  0.372
2011 Alder JK, Cogan JD, Brown AF, Anderson CJ, Lawson WE, Lansdorp PM, Phillips JA, Loyd JE, Chen JJ, Armanios M. Ancestral mutation in telomerase causes defects in repeat addition processivity and manifests as familial pulmonary fibrosis. Plos Genetics. 7: e1001352. PMID 21483807 DOI: 10.1371/Journal.Pgen.1001352  0.34
2011 Parry EM, Alder JK, Qi X, Chen JJ, Armanios M. Syndrome complex of bone marrow failure and pulmonary fibrosis predicts germline defects in telomerase. Blood. 117: 5607-11. PMID 21436073 DOI: 10.1182/Blood-2010-11-322149  0.33
2011 Parry EM, Alder JK, Lee SS, Phillips JA, Loyd JE, Duggal P, Armanios M. Decreased dyskerin levels as a mechanism of telomere shortening in X-linked dyskeratosis congenita. Journal of Medical Genetics. 48: 327-33. PMID 21415081 DOI: 10.1136/Jmg.2010.085100  0.305
2010 Lebson L, Gocke A, Rosenzweig J, Alder J, Civin C, Calabresi PA, Whartenby KA. Cutting edge: The transcription factor Kruppel-like factor 4 regulates the differentiation of Th17 cells independently of RORγt. Journal of Immunology (Baltimore, Md. : 1950). 185: 7161-4. PMID 21076063 DOI: 10.4049/Jimmunol.1002750  0.535
2010 Healey MA, Deaton SL, Alder JK, Winnepenninckx V, Casero RA, Herman JG. Id1 overexpression is independent of repression and epigenetic silencing of tumor suppressor genes in melanoma. Epigenetics. 5: 410-21. PMID 20484992 DOI: 10.4161/Epi.5.5.11929  0.316
2009 Armanios M, Alder JK, Parry EM, Karim B, Strong MA, Greider CW. Short telomeres are sufficient to cause the degenerative defects associated with aging. American Journal of Human Genetics. 85: 823-32. PMID 19944403 DOI: 10.1016/J.Ajhg.2009.10.028  0.305
2008 Alder JK, Chen JJ, Lancaster L, Danoff S, Su SC, Cogan JD, Vulto I, Xie M, Qi X, Tuder RM, Phillips JA, Lansdorp PM, Loyd JE, Armanios MY. Short telomeres are a risk factor for idiopathic pulmonary fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 13051-6. PMID 18753630 DOI: 10.1073/Pnas.0804280105  0.354
2008 Alder JK, Georgantas RW, Hildreth RL, Kaplan IM, Morisot S, Yu X, McDevitt M, Civin CI. Kruppel-like factor 4 is essential for inflammatory monocyte differentiation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 180: 5645-52. PMID 18390749 DOI: 10.1182/Blood.V110.11.239.239  0.589
2007 Armanios MY, Chen JJ, Cogan JD, Alder JK, Ingersoll RG, Markin C, Lawson WE, Xie M, Vulto I, Phillips JA, Lansdorp PM, Greider CW, Loyd JE. Telomerase mutations in families with idiopathic pulmonary fibrosis. The New England Journal of Medicine. 356: 1317-26. PMID 17392301 DOI: 10.1056/Nejmoa066157  0.331
2007 Georgantas RW, Hildreth R, Morisot S, Alder J, Liu CG, Heimfeld S, Calin GA, Croce CM, Civin CI. CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control. Proceedings of the National Academy of Sciences of the United States of America. 104: 2750-5. PMID 17293455 DOI: 10.1073/Pnas.0610983104  0.511
2006 Yu X, Alder JK, Chun JH, Friedman AD, Heimfeld S, Cheng L, Civin CI. HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Stem Cells (Dayton, Ohio). 24: 876-88. PMID 16513761 DOI: 10.1634/Stemcells.2005-0598  0.59
2006 Hildreth R, Georgantas RW, Patel R, Morisot S, Alder J, Civin CI. MicroRNA hsa-mir-16 Contributes to Regulation of Myeloid Differentiation of Human CD34+ Cells. Blood. 108: 1343-1343. DOI: 10.1182/Blood.V108.11.1343.1343  0.556
2006 Georgantas RW, Hildreth R, Morisot S, Alder J, Civin CI. MicroRNA hsa-mir-155 Blocks Myeloid and Erythroid Differentiation of Human CD34+ Cells. Blood. 108: 1337-1337. DOI: 10.1182/Blood.V108.11.1337.1337  0.551
2006 Georgantas RW, Hildreth R, Alder J, Croce CM, Calin GA, Civin CI. MicroRNA Expression and Regulation of Hematopoiesis in CD34+ Cells: A Bioinformatic Circuit Diagram of the Hematopoietic Differentiation Control. Blood. 108: 1334-1334. DOI: 10.1182/Blood.V108.11.1334.1334  0.564
2006 Alder JK, Georgantas RW, Hildreth RL, Yu X, Civin CI. Kruppel-Like Factor 4 Upregulates p21 and Downregulates Proliferation of Human and Mouse HSPCs, but Is Not Essential for Mouse HSPC Repopulation. Blood. 108: 1317-1317. DOI: 10.1182/Blood.V108.11.1317.1317  0.6
2006 Alder JK, Georgantas RW, Hildreth RL, Civin CI. 348. Kruppel-Like Factor 4 Regulates Proliferation of Human and Mouse Hematopoietic Stem-Progenitor Cells, but Is Not Essential for Mouse Hematopoietic Repopulation Molecular Therapy. 13: S132-S133. DOI: 10.1016/J.Ymthe.2006.08.406  0.603
2004 Alder JK, Georgantas RW, Yu X, Civin CI. KLF4 as a Mediator of Quiescence in Hematopoietic Stem/Progenitor Cells. Blood. 104: 4146-4146. DOI: 10.1182/Blood.V104.11.4146.4146  0.612
2003 De Las Peñas A, Pan SJ, Castaño I, Alder J, Cregg R, Cormack BP. Virulence-related surface glycoproteins in the yeast pathogen Candida glabrata are encoded in subtelomeric clusters and subject to RAP1- and SIR-dependent transcriptional silencing. Genes & Development. 17: 2245-58. PMID 12952896 DOI: 10.1101/Gad.1121003  0.303
2002 Dunn DM, Ishigami T, Pankow J, Niederhausern AV, Alder J, Hunt SC, Leppert MF, Lalouel JM, Weiss RB. Common variant of human NEDD4L activates a cryptic splice site to form a frameshifted transcript Journal of Human Genetics. 47: 665-676. PMID 12522688 DOI: 10.1007/S100380200102  0.337
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