Thomas Durcan, Ph.D. - Publications

2007 University of Notre Dame, Notre Dame, IN, United States 
Cell Biology

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Mohamed NV, Lépine P, Lacalle-Aurioles M, Sirois J, Mathur M, Reintsch W, Beitel LK, Fon EA, Durcan TM. Microfabricated disk technology: rapid scale up in midbrain organoid generation. Methods (San Diego, Calif.). PMID 34314827 DOI: 10.1016/j.ymeth.2021.07.008  1
2021 Das S, Abou-Haidar R, Rabalais H, Sun SDLW, Rosli Z, Chatpar K, Boivin MN, Tabatabaei M, Rogers C, Legault M, Lo D, Degroot C, Dagher A, Dyke SOM, Durcan TM, et al. The C-BIG Repository: an Institution-Level Open Science Platform. Neuroinformatics. PMID 34003431 DOI: 10.1007/s12021-021-09516-9  1
2021 Tavassoly O, Del Cid Pellitero E, Larroquette F, Cai E, Thomas RA, Soubannier V, Luo W, Durcan TM, Fon EA. Pharmacological Inhibition of Brain EGFR Activation By a BBB-penetrating Inhibitor, AZD3759, Attenuates α-synuclein Pathology in a Mouse Model of α-Synuclein Propagation. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33713002 DOI: 10.1007/s13311-021-01017-6  1
2021 Jin JW, Fan X, Del Cid-Pellitero E, Liu XX, Zhou L, Dai C, Gibbs E, He W, Li H, Wu X, Hill A, Leavitt BR, Cashman N, Liu L, Lu J, ... Durcan TM, et al. Development of an α-synuclein knockdown peptide and evaluation of its efficacy in Parkinson's disease models. Communications Biology. 4: 232. PMID 33608634 DOI: 10.1038/s42003-021-01746-6  1
2020 Castellanos-Montiel MJ, Chaineau M, Durcan TM. The Neglected Genes of ALS: Cytoskeletal Dynamics Impact Synaptic Degeneration in ALS. Frontiers in Cellular Neuroscience. 14: 594975. PMID 33281562 DOI: 10.3389/fncel.2020.594975  0.01
2020 Lacalle-Aurioles M, Cassel de Camps C, Zorca CE, Beitel LK, Durcan TM. Applying hiPSCs and Biomaterials Towards an Understanding and Treatment of Traumatic Brain Injury. Frontiers in Cellular Neuroscience. 14: 594304. PMID 33281561 DOI: 10.3389/fncel.2020.594304  1
2020 Zhang I, Lépine P, Han C, Lacalle-Aurioles M, Chen CX, Haag R, Durcan TM, Maysinger D. Nanotherapeutic Modulation of Human Neural Cells and Glioblastoma in Organoids and Monocultures. Cells. 9. PMID 33171886 DOI: 10.3390/cells9112434  0.01
2020 Siddu A, David LS, Lauinger N, Chen CX, St-Pierre M, Alpaugh M, Durcan T, Cicchetti F. Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication. Neurobiology of Disease. 105042. PMID 32798729 DOI: 10.1016/j.nbd.2020.105042  0.01
2020 Krahn AI, Wells C, Drewry DH, Beitel LK, Durcan TM, Axtman AD. Defining the Neural Kinome: Strategies and Opportunities for Small Molecule Drug Discovery to Target Neurodegenerative Diseases. Acs Chemical Neuroscience. PMID 32464049 DOI: 10.1021/acschemneuro.0c00176  1
2020 Thiry L, Hamel R, Pluchino S, Durcan T, Stifani S. Characterization of Human iPSC-derived Spinal Motor Neurons by Single-cell RNA Sequencing. Neuroscience. PMID 32380268 DOI: 10.1016/J.Neuroscience.2020.04.041  0.01
2020 Soubannier V, Maussion G, Chaineau M, Sigutova V, Rouleau G, Durcan TM, Stifani S. Characterization of human iPSC-derived astrocytes with potential for disease modeling and drug discovery. Neuroscience Letters. 135028. PMID 32380146 DOI: 10.1016/J.Neulet.2020.135028  0.01
2020 Jefri M, Bell S, Peng H, Hettige N, Maussion G, Soubannier V, Wu H, Silveira H, Theroux JF, Moquin L, Zhang X, Aouabed Z, Krishnan J, O'Leary LA, Antonyan L, ... ... Durcan TM, et al. Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells. Stem Cells Translational Medicine. PMID 32154672 DOI: 10.1002/Sctm.18-0180  1
2020 Martínez GF, Gazal NG, Quassollo G, Szalai AM, Cid-Pellitero ED, Durcan TM, Fon EA, Bisbal M, Stefani FD, Unsain N. Quantitative expansion microscopy for the characterization of the spectrin periodic skeleton of axons using fluorescence microscopy. Scientific Reports. 10: 2917. PMID 32076054 DOI: 10.1038/S41598-020-59856-W  1
2020 Semmler S, Gagné M, Garg P, Pickles SR, Baudouin C, Hamon-Keromen E, Destroismaisons L, Khalfallah Y, Chaineau M, Caron E, Bayne AN, Trempe JF, Cashman NR, Star AT, Haqqani AS, ... Durcan TM, et al. TNF receptor associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation. The Journal of Biological Chemistry. PMID 32029478 DOI: 10.1074/Jbc.Ra119.011215  1
2019 Gan-Or Z, Rao T, Leveille E, Degroot C, Chouinard S, Cicchetti F, Dagher A, Das S, Desautels A, Drouin-Ouellet J, Durcan T, Gagnon JF, Genge A, Karamchandani J, Lafontaine AL, et al. The Quebec Parkinson Network: A Researcher-Patient Matching Platform and Multimodal Biorepository. Journal of Parkinson's Disease. PMID 31868683 DOI: 10.3233/Jpd-191775  1
2019 De Snoo ML, Friesen EL, Zhang YT, Earnshaw R, Dorval G, Kapadia M, O'Hara DM, Agapova V, Chau H, Pellerito O, Tang MY, Wang X, Schmitt-Ulms G, Durcan TM, Fon EA, et al. Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death. Cell Death & Disease. 10: 907. PMID 31787745 DOI: 10.1038/S41419-019-2132-X  1
2019 Laflamme C, McKeever PM, Kumar R, Schwartz J, Kolahdouzan M, Chen CX, You Z, Benaliouad F, Gileadi O, McBride HM, Durcan TM, Edwards AM, Healy LM, Robertson J, McPherson PS. Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72. Elife. 8. PMID 31612854 DOI: 10.7554/Elife.48363  0.01
2019 Maussion G, Rocha C, Bernard G, Beitel LK, Durcan TM. Patient-Derived Stem Cells, Another Model, or the Missing Link Toward Novel Therapies for Autism Spectrum Disorders? Frontiers in Pediatrics. 7: 225. PMID 31245336 DOI: 10.3389/Fped.2019.00225  1
2019 Mohamed NV, Larroquette F, Beitel LK, Fon EA, Durcan TM. One Step Into the Future: New iPSC Tools to Advance Research in Parkinson's Disease and Neurological Disorders. Journal of Parkinson's Disease. PMID 30741685 DOI: 10.3233/JPD-181515  1
2018 Bell S, Maussion G, Jefri M, Peng H, Theroux JF, Silveira H, Soubannier V, Wu H, Hu P, Galat E, Torres-Platas SG, Boudreau-Pinsonneault C, O'Leary LA, Galat V, Turecki G, ... Durcan TM, et al. Disruption of GRIN2B Impairs Differentiation in Human Neurons. Stem Cell Reports. PMID 29937144 DOI: 10.1016/J.Stemcr.2018.05.018  1
2018 McLelland GL, Goiran T, Yi W, Dorval G, Chen CX, Lauinger ND, Krahn AI, Valimehr S, Rakovic A, Rouiller I, Durcan TM, Trempe JF, Fon EA. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. Elife. 7. PMID 29676259 DOI: 10.7554/eLife.32866  1
2018 Han C, Chaineau M, Chen CX, Beitel LK, Durcan TM. Open Science Meets Stem Cells: A New Drug Discovery Approach for Neurodegenerative Disorders. Frontiers in Neuroscience. 12: 47. PMID 29467610 DOI: 10.3389/fnins.2018.00047  1
2017 Manecka DL, Vanderperre B, Fon EA, Durcan TM. The Neuroprotective Role of Protein Quality Control in Halting the Development of Alpha-Synuclein Pathology. Frontiers in Molecular Neuroscience. 10: 311. PMID 29021741 DOI: 10.3389/fnmol.2017.00311  1
2016 Das S, Glatard T, Rogers C, Saigle J, Paiva S, MacIntyre L, Safi-Harab M, Rousseau ME, Stirling J, Khalili-Mahani N, MacFarlane D, Kostopoulos P, Rioux P, Madjar C, Lecours-Boucher X, ... ... Durcan TM, et al. Cyberinfrastructure for Open Science at the Montreal Neurological Institute. Frontiers in Neuroinformatics. 10: 53. PMID 28111547 DOI: 10.3389/Fninf.2016.00053  1
2016 Roberts RF, Tang MY, Fon EA, Durcan TM. Defending the mitochondria: the pathways of mitophagy and mitochondrial-derived vesicles. The International Journal of Biochemistry & Cell Biology. PMID 27443527 DOI: 10.1016/j.biocel.2016.07.020  1
2015 Durcan TM, Fon EA. The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications. Genes & Development. 29: 989-99. PMID 25995186 DOI: 10.1101/gad.262758.115  1
2015 Durcan TM, Fon EA. USP8 and PARK2/parkin-mediated mitophagy. Autophagy. 11: 428-9. PMID 25700639 DOI: 10.1080/15548627.2015.1009794  1
2015 Aguileta MA, Korac J, Durcan TM, Trempe JF, Haber M, Gehring K, Elsasser S, Waidmann O, Fon EA, Husnjak K. The E3 ubiquitin ligase parkin is recruited to the 26 S proteasome via the proteasomal ubiquitin receptor Rpn13. The Journal of Biological Chemistry. 290: 7492-505. PMID 25666615 DOI: 10.1074/jbc.M114.614925  1
2014 Durcan TM, Tang MY, Pérusse JR, Dashti EA, Aguileta MA, McLelland GL, Gros P, Shaler TA, Faubert D, Coulombe B, Fon EA. USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin. The Embo Journal. 33: 2473-91. PMID 25216678 DOI: 10.15252/Embj.201489729  1
2013 Montie HL, Durcan TM. The cell and molecular biology of neurodegenerative diseases: an overview. Frontiers in Neurology. 4: 194. PMID 24348458 DOI: 10.3389/Fneur.2013.00194  0.01
2013 Durcan TM, Fon EA. Ataxin-3 and its e3 partners: implications for machado-joseph disease. Frontiers in Neurology. 4: 46. PMID 23653622 DOI: 10.3389/fneur.2013.00046  1
2012 Durcan TM, Kontogiannea M, Bedard N, Wing SS, Fon EA. Ataxin-3 deubiquitination is coupled to Parkin ubiquitination via E2 ubiquitin-conjugating enzyme. The Journal of Biological Chemistry. 287: 531-41. PMID 22081612 DOI: 10.1074/jbc.M111.288449  1
2011 Durcan TM, Fon EA. Mutant ataxin-3 promotes the autophagic degradation of parkin. Autophagy. 7: 233-4. PMID 21116127 DOI: 10.4161/auto.7.2.14224  1
2011 Durcan TM, Kontogiannea M, Thorarinsdottir T, Fallon L, Williams AJ, Djarmati A, Fantaneanu T, Paulson HL, Fon EA. The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability. Human Molecular Genetics. 20: 141-54. PMID 20940148 DOI: 10.1093/hmg/ddq452  1
2010 Collins ES, Hornick JE, Durcan TM, Collins NS, Archer W, Karanjeet KB, Vaughan KT, Hinchcliffe EH. Centrosome biogenesis continues in the absence of microtubules during prolonged S-phase arrest. Journal of Cellular Physiology. 225: 454-65. PMID 20458743 DOI: 10.1002/Jcp.22222  1
2009 Scanlon TC, Gottlieb B, Durcan TM, Fon EA, Beitel LK, Trifiro MA. Isolation of human proteasomes and putative proteasome-interacting proteins using a novel affinity chromatography method. Experimental Cell Research. 315: 176-89. PMID 19013454 DOI: 10.1016/j.yexcr.2008.10.027  1
2008 Durcan TM, Halpin ES, Rao T, Collins NS, Tribble EK, Hornick JE, Hinchcliffe EH. Tektin 2 is required for central spindle microtubule organization and the completion of cytokinesis. The Journal of Cell Biology. 181: 595-603. PMID 18474621 DOI: 10.1083/Jcb.200711160  1
2008 Durcan TM, Halpin ES, Casaletti L, Vaughan KT, Pierson MR, Woods S, Hinchcliffe EH. Centrosome duplication proceeds during mimosine-induced G1 cell cycle arrest. Journal of Cellular Physiology. 215: 182-91. PMID 17960592 DOI: 10.1002/Jcp.21298  1
2007 Durcan TM, Hinchcliffe EH. Digital image files in light microscopy. Methods in Cell Biology. 81: 315-33. PMID 17519173 DOI: 10.1016/S0091-679X(06)81015-0  1
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