Thomas Durcan, Ph.D. - Publications

Affiliations: 
2007 University of Notre Dame, Notre Dame, IN, United States 
Area:
Cell Biology

4/85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Collins ES, Hornick JE, Durcan TM, Collins NS, Archer W, Karanjeet KB, Vaughan KT, Hinchcliffe EH. Centrosome biogenesis continues in the absence of microtubules during prolonged S-phase arrest. Journal of Cellular Physiology. 225: 454-65. PMID 20458743 DOI: 10.1002/Jcp.22222  0.703
2008 Durcan TM, Halpin ES, Rao T, Collins NS, Tribble EK, Hornick JE, Hinchcliffe EH. Tektin 2 is required for central spindle microtubule organization and the completion of cytokinesis. The Journal of Cell Biology. 181: 595-603. PMID 18474621 DOI: 10.1083/Jcb.200711160  0.512
2008 Durcan TM, Halpin ES, Casaletti L, Vaughan KT, Pierson MR, Woods S, Hinchcliffe EH. Centrosome duplication proceeds during mimosine-induced G1 cell cycle arrest. Journal of Cellular Physiology. 215: 182-91. PMID 17960592 DOI: 10.1002/Jcp.21298  0.612
2007 Durcan TM, Hinchcliffe EH. Digital image files in light microscopy. Methods in Cell Biology. 81: 315-33. PMID 17519173 DOI: 10.1016/S0091-679X(06)81015-0  0.548
Low-probability matches (unlikely to be authored by this person)
2022 Hettige NC, Peng H, Wu H, Zhang X, Yerko V, Zhang Y, Jefri M, Soubannier V, Maussion G, Alsuwaidi S, Ni A, Rocha C, Krishnan J, McCarty V, Antonyan L, ... ... Durcan TM, et al. FOXG1 dose tunes cell proliferation dynamics in human forebrain progenitor cells. Stem Cell Reports. PMID 35148845 DOI: 10.1016/j.stemcr.2022.01.010  0.28
2024 Banks E, Francis V, Lin SJ, Kharfallah F, Fonov V, Levesque M, Han C, Kulasekaran G, Tuznik M, Bayati A, Al-Khater R, Alkuraya FS, Argyriou L, Babaei M, Bahlo M, ... ... Durcan TM, et al. Loss of symmetric cell division of apical neural progenitors drives -related developmental and epileptic encephalopathy. Medrxiv : the Preprint Server For Health Sciences. PMID 38352438 DOI: 10.1101/2022.08.23.22278845  0.273
2022 Bayati A, Banks E, Han C, Luo W, Reintsch WE, Zorca CE, Shlaifer I, Del Cid Pellitero E, Vanderperre B, McBride HM, Fon EA, Durcan TM, McPherson PS. Rapid macropinocytic transfer of α-synuclein to lysosomes. Cell Reports. 40: 111102. PMID 35858558 DOI: 10.1016/j.celrep.2022.111102  0.257
2021 Chen CX, Abdian N, Maussion G, Thomas RA, Demirova I, Cai E, Tabatabaei M, Beitel LK, Karamchandani J, Fon EA, Durcan TM. A Multistep Workflow to Evaluate Newly Generated iPSCs and Their Ability to Generate Different Cell Types. Methods and Protocols. 4. PMID 34287353 DOI: 10.3390/mps4030050  0.23
2024 Piscopo VEC, Chapleau A, Blaszczyk GJ, Sirois J, You Z, Soubannier V, Chen CX, Bernard G, Antel JP, Durcan TM. The use of a SOX10 reporter toward ameliorating oligodendrocyte lineage differentiation from human induced pluripotent stem cells. Glia. PMID 38497409 DOI: 10.1002/glia.24524  0.214
2022 Dong J, Duchesne A, Bayne AN, Mohamed NV, Yi W, Mathur M, Chen CXQ, You Z, Abdian N, Taylor L, Fon EA, Durcan TM, Trempe JF. An Approach to Measuring Protein Turnover in Human Induced Pluripotent Stem Cell Organoids by Mass Spectrometry. Methods (San Diego, Calif.). PMID 35331912 DOI: 10.1016/j.ymeth.2022.03.011  0.199
2022 Chen CX, You Z, Abdian N, Sirois J, Shlaifer I, Tabatabaei M, Boivin MN, Gaborieau L, Karamchandani J, Beitel LK, Fon EA, Durcan TM. Generation of homozygous PRKN, PINK1 and double PINK1/PRKN knockout cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 editing. Stem Cell Research. 62: 102806. PMID 35561458 DOI: 10.1016/j.scr.2022.102806  0.178
2018 Han C, Chaineau M, Chen CX, Beitel LK, Durcan TM. Open Science Meets Stem Cells: A New Drug Discovery Approach for Neurodegenerative Disorders. Frontiers in Neuroscience. 12: 47. PMID 29467610 DOI: 10.3389/fnins.2018.00047  0.173
2020 Thiry L, Hamel R, Pluchino S, Durcan T, Stifani S. Characterization of Human iPSC-derived Spinal Motor Neurons by Single-cell RNA Sequencing. Neuroscience. PMID 32380268 DOI: 10.1016/J.Neuroscience.2020.04.041  0.172
2022 Senkevich K, Zorca CE, Dworkind A, Rudakou U, Somerville E, Yu E, Ermolaev A, Nikanorova D, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Fahn S, Waters C, Monchi O, ... ... Durcan TM, et al. GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson's disease. Brain : a Journal of Neurology. PMID 36370000 DOI: 10.1093/brain/awac413  0.168
2020 Martínez GF, Gazal NG, Quassollo G, Szalai AM, Cid-Pellitero ED, Durcan TM, Fon EA, Bisbal M, Stefani FD, Unsain N. Quantitative expansion microscopy for the characterization of the spectrin periodic skeleton of axons using fluorescence microscopy. Scientific Reports. 10: 2917. PMID 32076054 DOI: 10.1038/S41598-020-59856-W  0.167
2015 Durcan TM, Fon EA. The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications. Genes & Development. 29: 989-99. PMID 25995186 DOI: 10.1101/gad.262758.115  0.161
2023 Bayati A, Luo W, Del Cid-Pellitero E, Fon EA, Durcan TM, McPherson PS. Visualization of α-synuclein trafficking via nanogold labeling and electron microscopy. Star Protocols. 4: 102113. PMID 36861831 DOI: 10.1016/j.xpro.2023.102113  0.16
2019 De Snoo ML, Friesen EL, Zhang YT, Earnshaw R, Dorval G, Kapadia M, O'Hara DM, Agapova V, Chau H, Pellerito O, Tang MY, Wang X, Schmitt-Ulms G, Durcan TM, Fon EA, et al. Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death. Cell Death & Disease. 10: 907. PMID 31787745 DOI: 10.1038/S41419-019-2132-X  0.159
2021 Mohamed NV, Sirois J, Ramamurthy J, Mathur M, Lépine P, Deneault E, Maussion G, Nicouleau M, Chen CX, Abdian N, Soubannier V, Cai E, Nami H, Thomas RA, Wen D, ... ... Durcan TM, et al. Midbrain organoids with an gene triplication model key features of synucleinopathy. Brain Communications. 3: fcab223. PMID 34632384 DOI: 10.1093/braincomms/fcab223  0.156
2023 Cassel de Camps C, Mok S, Ashby E, Li C, Lépine P, Durcan TM, Moraes C. Compressive molding of engineered tissues thermoresponsive hydrogel devices. Lab On a Chip. PMID 36916609 DOI: 10.1039/d3lc00007a  0.154
2023 Castellanos-Montiel MJ, Chaineau M, Franco-Flores AK, Haghi G, Carrillo-Valenzuela D, Reintsch WE, Chen CX, Durcan TM. An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids. Cells. 12. PMID 36831212 DOI: 10.3390/cells12040545  0.15
2023 Jones-Tabah J, He K, Senkevich K, Karpilovsky N, Deyab G, Cousineau Y, Nikanorova D, Goldsmith T, Pellitero EDC, Chen CX, Luo W, You Z, Abdian N, Pietrantonio I, Goiran T, ... ... Durcan TM, et al. The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons. Biorxiv : the Preprint Server For Biology. PMID 38014143 DOI: 10.1101/2023.11.11.566693  0.15
2024 Eldeeb MA, Bayne AN, Fallahi A, Goiran T, MacDougall EJ, Soumbasis A, Zorca CE, Tabah JJ, Thomas RA, Karpilovsky N, Mathur M, Durcan TM, Trempe JF, Fon EA. Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress. Proceedings of the National Academy of Sciences of the United States of America. 121: e2313540121. PMID 38416681 DOI: 10.1073/pnas.2313540121  0.15
2021 Cassel de Camps C, Aslani S, Stylianesis N, Nami H, Mohamed NV, Durcan TM, Moraes C. Hydrogel Mechanics Influence the Growth and Development of Embedded Brain Organoids. Acs Applied Bio Materials. 5: 214-224. PMID 35014820 DOI: 10.1021/acsabm.1c01047  0.148
2022 Lackie RE, de Miranda AS, Lim MP, Novikov V, Madrer N, Karunatilleke NC, Rutledge BS, Tullo S, Brickenden A, Maitland MER, Greenberg D, Gallino D, Luo W, Attaran A, Shlaifer I, ... ... Durcan TM, et al. Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo. Acta Neuropathologica. PMID 36121476 DOI: 10.1007/s00401-022-02491-8  0.147
2020 Zhang I, Lépine P, Han C, Lacalle-Aurioles M, Chen CX, Haag R, Durcan TM, Maysinger D. Nanotherapeutic Modulation of Human Neural Cells and Glioblastoma in Organoids and Monocultures. Cells. 9. PMID 33171886 DOI: 10.3390/cells9112434  0.145
2023 McGoldrick P, Lau A, You Z, Durcan TM, Robertson J. Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules. Cell Reports. 42: 112134. PMID 36821445 DOI: 10.1016/j.celrep.2023.112134  0.144
2024 Flax RG, Rosston P, Rocha C, Anderson B, Capener JL, Durcan TM, Drewry DH, Prinos P, Axtman AD. Illumination of understudied ciliary kinases. Frontiers in Molecular Biosciences. 11: 1352781. PMID 38523660 DOI: 10.3389/fmolb.2024.1352781  0.144
2024 Jones-Tabah J, He K, Senkevich K, Karpilovsky N, Deyab G, Cousineau Y, Nikanorova D, Goldsmith T, Pellitero ED, Chen CX, Luo W, You Z, Abdian N, Pietrantonio I, Goiran T, ... ... Durcan TM, et al. The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons. Research Square. PMID 38562709 DOI: 10.21203/rs.3.rs-3979098/v1  0.144
2023 Dorion MF, Yaqubi M, Senkevich K, Kieran NW, MacDonald A, Chen CX, Luo W, Wallis A, Shlaifer I, Hall JA, Dudley RWR, Glass IA, Stratton JA, Fon E, Bartels T, ... ... Durcan TM, et al. MerTK is a mediator of alpha-synuclein fibril uptake by human microglia. Brain : a Journal of Neurology. PMID 37671615 DOI: 10.1093/brain/awad298  0.141
2020 Siddu A, David LS, Lauinger N, Chen CX, St-Pierre M, Alpaugh M, Durcan T, Cicchetti F. Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication. Neurobiology of Disease. 105042. PMID 32798729 DOI: 10.1016/j.nbd.2020.105042  0.138
2011 Durcan TM, Kontogiannea M, Thorarinsdottir T, Fallon L, Williams AJ, Djarmati A, Fantaneanu T, Paulson HL, Fon EA. The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability. Human Molecular Genetics. 20: 141-54. PMID 20940148 DOI: 10.1093/hmg/ddq452  0.137
2021 Imanbekova M, Suarasan S, Rojalin T, Mizenko RR, Hilt S, Mathur M, Lepine P, Nicouleau M, Mohamed NV, Durcan TM, Carney RP, Voss JC, Wachsmann-Hogiu S. Identification of amyloid beta in small extracellular vesicles Raman spectroscopy. Nanoscale Advances. 3: 4119-4132. PMID 34355118 DOI: 10.1039/d1na00330e  0.129
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Durcan TM, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.126
2015 Aguileta MA, Korac J, Durcan TM, Trempe JF, Haber M, Gehring K, Elsasser S, Waidmann O, Fon EA, Husnjak K. The E3 ubiquitin ligase parkin is recruited to the 26 S proteasome via the proteasomal ubiquitin receptor Rpn13. The Journal of Biological Chemistry. 290: 7492-505. PMID 25666615 DOI: 10.1074/jbc.M114.614925  0.125
2024 Thiry L, Sirois J, Durcan TM, Stifani S. Generation of human iPSC-derived phrenic-like motor neurons to model respiratory motor neuron degeneration in ALS. Communications Biology. 7: 238. PMID 38418587 DOI: 10.1038/s42003-024-05925-z  0.122
2019 Mohamed N, Mathur M, da Silva RV, Beitel LK, Fon EA, Durcan TM. Generation of human midbrain organoids from induced pluripotent stem cells Mni Open Research. 3: 1. DOI: 10.12688/MNIOPENRES.12816.1  0.121
2022 Vranas M, Lu Y, Rasool S, Croteau N, Krett JD, Sauvé V, Gehring K, Fon EA, Durcan TM, Trempe JF. Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria. Open Biology. 12: 210255. PMID 35042405 DOI: 10.1098/rsob.210255  0.121
2024 Dorion MF, Casas D, Shlaifer I, Yaqubi M, Fleming P, Karpilovsky N, Chen CX, Nicouleau M, Piscopo VEC, MacDougall EJ, Alluli A, Goldsmith TM, Schneider A, Dorion S, Aprahamian N, ... ... Durcan TM, et al. An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders. Molecular Neurodegeneration. 19: 31. PMID 38576039 DOI: 10.1186/s13024-024-00723-x  0.12
2024 Lépine S, Nauleau-Javaudin A, Deneault E, Chen CX, Abdian N, Franco-Flores AK, Haghi G, Castellanos-Montiel MJ, Maussion G, Chaineau M, Durcan TM. Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons. Iscience. 27: 109166. PMID 38433895 DOI: 10.1016/j.isci.2024.109166  0.117
2023 Schorova L, Bedard N, Khayachi A, Ho HH, Bolivar-Pedroso J, Huynh J, Piccirelli M, Wang Y, Plourde M, Luo W, Del Cid-Pellitero E, Shlaifer I, Castellanos-Montiel MJ, Yu Z, Valenzuela DVC, ... ... Durcan TM, et al. USP19 deubiquitinase inactivation regulates α-synuclein ubiquitination and inhibits accumulation of Lewy body-like aggregates in mice. Npj Parkinson's Disease. 9: 157. PMID 38017009 DOI: 10.1038/s41531-023-00601-1  0.116
2013 Montie HL, Durcan TM. The cell and molecular biology of neurodegenerative diseases: an overview. Frontiers in Neurology. 4: 194. PMID 24348458 DOI: 10.3389/Fneur.2013.00194  0.114
2014 Durcan TM, Tang MY, Pérusse JR, Dashti EA, Aguileta MA, McLelland GL, Gros P, Shaler TA, Faubert D, Coulombe B, Fon EA. USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin. The Embo Journal. 33: 2473-91. PMID 25216678 DOI: 10.15252/Embj.201489729  0.114
2017 Manecka DL, Vanderperre B, Fon EA, Durcan TM. The Neuroprotective Role of Protein Quality Control in Halting the Development of Alpha-Synuclein Pathology. Frontiers in Molecular Neuroscience. 10: 311. PMID 29021741 DOI: 10.3389/fnmol.2017.00311  0.114
2023 Maussion G, Rocha C, Abdian N, Yang D, Turk J, Carrillo Valenzuela D, Pimentel L, You Z, Morquette B, Nicouleau M, Deneault E, Higgins S, Chen CX, Reintsch WE, Ho S, ... ... Durcan TM, et al. Transcriptional Dysregulation and Impaired Neuronal Activity in Knock-Out and Fragile X Patients' iPSC-Derived Models. International Journal of Molecular Sciences. 24. PMID 37834379 DOI: 10.3390/ijms241914926  0.112
2018 Bell S, Maussion G, Jefri M, Peng H, Theroux JF, Silveira H, Soubannier V, Wu H, Hu P, Galat E, Torres-Platas SG, Boudreau-Pinsonneault C, O'Leary LA, Galat V, Turecki G, ... Durcan TM, et al. Disruption of GRIN2B Impairs Differentiation in Human Neurons. Stem Cell Reports. PMID 29937144 DOI: 10.1016/J.Stemcr.2018.05.018  0.111
2020 Jefri M, Bell S, Peng H, Hettige N, Maussion G, Soubannier V, Wu H, Silveira H, Theroux JF, Moquin L, Zhang X, Aouabed Z, Krishnan J, O'Leary LA, Antonyan L, ... ... Durcan TM, et al. Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells. Stem Cells Translational Medicine. PMID 32154672 DOI: 10.1002/Sctm.18-0180  0.11
2020 Krahn AI, Wells C, Drewry DH, Beitel LK, Durcan TM, Axtman AD. Defining the Neural Kinome: Strategies and Opportunities for Small Molecule Drug Discovery to Target Neurodegenerative Diseases. Acs Chemical Neuroscience. PMID 32464049 DOI: 10.1021/acschemneuro.0c00176  0.11
2011 Durcan TM, Fon EA. Mutant ataxin-3 promotes the autophagic degradation of parkin. Autophagy. 7: 233-4. PMID 21116127 DOI: 10.4161/auto.7.2.14224  0.109
2022 Bérard M, Sheta R, Malvaut S, Rodriguez-Aller R, Teixeira M, Idi W, Turmel R, Alpaugh M, Dubois M, Dahmene M, Sales C, Lamontagne-Proulx J, St-Pierre MK, Tavassoly O, Luo W, ... ... Durcan TM, et al. A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease. Plos Biology. 20: e3001578. PMID 35263320 DOI: 10.1371/journal.pbio.3001578  0.108
2020 Castellanos-Montiel MJ, Chaineau M, Durcan TM. The Neglected Genes of ALS: Cytoskeletal Dynamics Impact Synaptic Degeneration in ALS. Frontiers in Cellular Neuroscience. 14: 594975. PMID 33281562 DOI: 10.3389/fncel.2020.594975  0.107
2019 Mohamed NV, Larroquette F, Beitel LK, Fon EA, Durcan TM. One Step Into the Future: New iPSC Tools to Advance Research in Parkinson's Disease and Neurological Disorders. Journal of Parkinson's Disease. PMID 30741685 DOI: 10.3233/JPD-181515  0.107
2022 Soubannier V, Chaineau M, Gursu L, Haghi G, Franco Flores AK, Rouleau G, Durcan TM, Stifani S. Rapid Generation of Ventral Spinal Cord-like Astrocytes from Human iPSCs for Modeling Non-Cell Autonomous Mechanisms of Lower Motor Neuron Disease. Cells. 11. PMID 35159209 DOI: 10.3390/cells11030399  0.103
2022 Lépine S, Castellanos-Montiel MJ, Durcan TM. TDP-43 dysregulation and neuromuscular junction disruption in amyotrophic lateral sclerosis. Translational Neurodegeneration. 11: 56. PMID 36575535 DOI: 10.1186/s40035-022-00331-z  0.103
2021 Mohamed NV, Lépine P, Lacalle-Aurioles M, Sirois J, Mathur M, Reintsch W, Beitel LK, Fon EA, Durcan TM. Microfabricated disk technology: rapid scale up in midbrain organoid generation. Methods (San Diego, Calif.). PMID 34314827 DOI: 10.1016/j.ymeth.2021.07.008  0.102
2021 Deneault E, Chaineau M, Nicouleau M, Castellanos Montiel MJ, Franco Flores AK, Haghi G, Chen CX, Abdian N, Shlaifer I, Beitel LK, Durcan TM. A streamlined CRISPR workflow to introduce mutations and generate isogenic iPSCs for modeling amyotrophic lateral sclerosis. Methods (San Diego, Calif.). PMID 34500068 DOI: 10.1016/j.ymeth.2021.09.002  0.101
2021 Tavassoly O, Del Cid Pellitero E, Larroquette F, Cai E, Thomas RA, Soubannier V, Luo W, Durcan TM, Fon EA. Pharmacological Inhibition of Brain EGFR Activation By a BBB-penetrating Inhibitor, AZD3759, Attenuates α-synuclein Pathology in a Mouse Model of α-Synuclein Propagation. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33713002 DOI: 10.1007/s13311-021-01017-6  0.099
2021 Das S, Abou-Haidar R, Rabalais H, Sun SDLW, Rosli Z, Chatpar K, Boivin MN, Tabatabaei M, Rogers C, Legault M, Lo D, Degroot C, Dagher A, Dyke SOM, Durcan TM, et al. The C-BIG Repository: an Institution-Level Open Science Platform. Neuroinformatics. PMID 34003431 DOI: 10.1007/s12021-021-09516-9  0.099
2023 Feller B, Fallon A, Luo W, Nguyen PT, Shlaifer I, Lee AK, Chofflet N, Yi N, Khaled H, Karkout S, Bourgault S, Durcan TM, Takahashi H. α-Synuclein Preformed Fibrils Bind to β-Neurexins and Impair β-Neurexin-Mediated Presynaptic Organization. Cells. 12. PMID 37048156 DOI: 10.3390/cells12071083  0.099
2022 Alshafie W, Fotouhi M, Shlaifer I, Ayoubi R, Edwards AM, Durcan TM, McPherson PS, Laflamme C. Identification of highly specific antibodies for Serine/threonine-protein kinase TBK1 for use in immunoblot, immunoprecipitation and immunofluorescence. F1000research. 11: 977. PMID 36415206 DOI: 10.12688/f1000research.124632.1  0.096
2022 X-Q Chen C, Deneault E, Abdian N, You Z, Sirois J, Nicouleau M, Shlaifer I, Villegas L, Boivin MN, Gaborieau L, Karamchandani J, Beitel LK, Fon EA, Durcan TM. Generation of patient-derived pluripotent stem cell-lines and CRISPR modified isogenic controls with mutations in the Parkinson's associated GBA gene. Stem Cell Research. 64: 102919. PMID 36130446 DOI: 10.1016/j.scr.2022.102919  0.095
2020 Lacalle-Aurioles M, Cassel de Camps C, Zorca CE, Beitel LK, Durcan TM. Applying hiPSCs and Biomaterials Towards an Understanding and Treatment of Traumatic Brain Injury. Frontiers in Cellular Neuroscience. 14: 594304. PMID 33281561 DOI: 10.3389/fncel.2020.594304  0.095
2012 Durcan TM, Kontogiannea M, Bedard N, Wing SS, Fon EA. Ataxin-3 deubiquitination is coupled to Parkin ubiquitination via E2 ubiquitin-conjugating enzyme. The Journal of Biological Chemistry. 287: 531-41. PMID 22081612 DOI: 10.1074/jbc.M111.288449  0.092
2023 Tullo S, Miranda AS, Del Cid-Pellitero E, Lim MP, Gallino D, Attaran A, Patel R, Novikov V, Park M, Beraldo FH, Luo W, Shlaifer I, Durcan TM, Bussey TJ, Saksida LM, et al. Neuroanatomical and cognitive biomarkers of alpha-synuclein propagation in a mouse model of synucleinopathy prior to onset of motor symptoms. Journal of Neurochemistry. PMID 37804203 DOI: 10.1111/jnc.15967  0.091
2016 Roberts RF, Tang MY, Fon EA, Durcan TM. Defending the mitochondria: the pathways of mitophagy and mitochondrial-derived vesicles. The International Journal of Biochemistry & Cell Biology. PMID 27443527 DOI: 10.1016/j.biocel.2016.07.020  0.089
2015 Durcan TM, Fon EA. USP8 and PARK2/parkin-mediated mitophagy. Autophagy. 11: 428-9. PMID 25700639 DOI: 10.1080/15548627.2015.1009794  0.088
2021 Jin JW, Fan X, Del Cid-Pellitero E, Liu XX, Zhou L, Dai C, Gibbs E, He W, Li H, Wu X, Hill A, Leavitt BR, Cashman N, Liu L, Lu J, ... Durcan TM, et al. Development of an α-synuclein knockdown peptide and evaluation of its efficacy in Parkinson's disease models. Communications Biology. 4: 232. PMID 33608634 DOI: 10.1038/s42003-021-01746-6  0.086
2019 Maussion G, Rocha C, Bernard G, Beitel LK, Durcan TM. Patient-Derived Stem Cells, Another Model, or the Missing Link Toward Novel Therapies for Autism Spectrum Disorders? Frontiers in Pediatrics. 7: 225. PMID 31245336 DOI: 10.3389/Fped.2019.00225  0.082
2023 Stevens MU, Croteau N, Eldeeb MA, Antico O, Zeng ZW, Toth R, Durcan TM, Springer W, Fon EA, Muqit MM, Trempe JF. Structure-based design and characterization of Parkin-activating mutations. Life Science Alliance. 6. PMID 36941054 DOI: 10.26508/lsa.202201419  0.081
2020 Semmler S, Gagné M, Garg P, Pickles SR, Baudouin C, Hamon-Keromen E, Destroismaisons L, Khalfallah Y, Chaineau M, Caron E, Bayne AN, Trempe JF, Cashman NR, Star AT, Haqqani AS, ... Durcan TM, et al. TNF receptor associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation. The Journal of Biological Chemistry. PMID 32029478 DOI: 10.1074/Jbc.Ra119.011215  0.079
2022 Sheta R, Teixeira M, Idi W, Pierre M, de Rus Jacquet A, Emond V, Zorca CE, Vanderperre B, Durcan TM, Fon EA, Calon F, Chahine M, Oueslati A. Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons. Scientific Reports. 12: 17176. PMID 36229560 DOI: 10.1038/s41598-022-22158-4  0.075
2013 Durcan TM, Fon EA. Ataxin-3 and its e3 partners: implications for machado-joseph disease. Frontiers in Neurology. 4: 46. PMID 23653622 DOI: 10.3389/fneur.2013.00046  0.068
2016 Das S, Glatard T, Rogers C, Saigle J, Paiva S, MacIntyre L, Safi-Harab M, Rousseau ME, Stirling J, Khalili-Mahani N, MacFarlane D, Kostopoulos P, Rioux P, Madjar C, Lecours-Boucher X, ... ... Durcan TM, et al. Cyberinfrastructure for Open Science at the Montreal Neurological Institute. Frontiers in Neuroinformatics. 10: 53. PMID 28111547 DOI: 10.3389/Fninf.2016.00053  0.061
2021 Kwan C, Kang MS, Nuara SG, Gourdon JC, Bédard D, Tardif CL, Hopewell R, Ross K, Bdair H, Hamadjida A, Massarweh G, Soucy JP, Luo W, Del Cid Pellitero E, Shlaifer I, ... Durcan TM, et al. Co-registration of Imaging Modalities (MRI, CT and PET) to Perform Frameless Stereotaxic Robotic Injections in the Common Marmoset. Neuroscience. PMID 34774970 DOI: 10.1016/j.neuroscience.2021.11.009  0.06
2019 Gan-Or Z, Rao T, Leveille E, Degroot C, Chouinard S, Cicchetti F, Dagher A, Das S, Desautels A, Drouin-Ouellet J, Durcan T, Gagnon JF, Genge A, Karamchandani J, Lafontaine AL, et al. The Quebec Parkinson Network: A Researcher-Patient Matching Platform and Multimodal Biorepository. Journal of Parkinson's Disease. PMID 31868683 DOI: 10.3233/Jpd-191775  0.057
2019 Laflamme C, McKeever PM, Kumar R, Schwartz J, Kolahdouzan M, Chen CX, You Z, Benaliouad F, Gileadi O, McBride HM, Durcan TM, Edwards AM, Healy LM, Robertson J, McPherson PS. Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72. Elife. 8. PMID 31612854 DOI: 10.7554/Elife.48363  0.054
2018 McLelland GL, Goiran T, Yi W, Dorval G, Chen CX, Lauinger ND, Krahn AI, Valimehr S, Rakovic A, Rouiller I, Durcan TM, Trempe JF, Fon EA. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. Elife. 7. PMID 29676259 DOI: 10.7554/eLife.32866  0.052
2021 Maussion G, Thomas RA, Demirova I, Gu G, Cai E, Chen CX, Abdian N, Strauss TJP, Kelaï S, Nauleau-Javaudin A, Beitel LK, Ramoz N, Gorwood P, Durcan TM. Auto-qPCR; a python-based web app for automated and reproducible analysis of qPCR data. Scientific Reports. 11: 21293. PMID 34716395 DOI: 10.1038/s41598-021-99727-6  0.051
2009 Scanlon TC, Gottlieb B, Durcan TM, Fon EA, Beitel LK, Trifiro MA. Isolation of human proteasomes and putative proteasome-interacting proteins using a novel affinity chromatography method. Experimental Cell Research. 315: 176-89. PMID 19013454 DOI: 10.1016/j.yexcr.2008.10.027  0.049
2023 Hooshmandi M, Sharma V, Thörn Perez C, Sood R, Krimbacher K, Wong C, Lister KC, Ureña Guzmán A, Bartley TD, Rocha C, Maussion G, Nadler E, Roque PM, Gantois I, Popic J, ... ... Durcan TM, et al. Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome. Neuron. PMID 37473758 DOI: 10.1016/j.neuron.2023.06.017  0.041
2023 Dorion MF, Yaqubi M, Murdoch HJ, Hall JA, Dudley R, Antel JP, Durcan TM, Healy LM. Systematic comparison of culture media uncovers phenotypic shift of primary human microglia defined by reduced reliance to CSF1R signaling. Glia. PMID 36680780 DOI: 10.1002/glia.24338  0.036
2023 Ayoubi R, Ryan J, Fotouhi M, Alshafie W, Bolivar SG, Moleon VR, Reintsch W, Eckmann P, Worrall D, McDowell I, Southern K, Durcan TM, Brown CM, Bandrowski A, Virk HS, et al. Quantifying the coverage of the human proteome with renewable antibodies. Biorxiv : the Preprint Server For Biology. PMID 37398479 DOI: 10.1101/2023.06.01.543292  0.034
2020 Soubannier V, Maussion G, Chaineau M, Sigutova V, Rouleau G, Durcan TM, Stifani S. Characterization of human iPSC-derived astrocytes with potential for disease modeling and drug discovery. Neuroscience Letters. 135028. PMID 32380146 DOI: 10.1016/J.Neulet.2020.135028  0.031
2023 Ayoubi R, Ryan J, Biddle MS, Alshafie W, Fotouhi M, Bolivar SG, Ruiz Moleon V, Eckmann P, Worrall D, McDowell I, Southern K, Reintsch W, Durcan TM, Brown C, Bandrowski A, et al. Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications. Elife. 12. PMID 37995198 DOI: 10.7554/eLife.91645  0.03
2023 Durcan TM, Axtman AD. Editorial: The next generation of tools and technologies for studying human neurons in a dish. Frontiers in Cellular Neuroscience. 17: 1196543. PMID 37124399 DOI: 10.3389/fncel.2023.1196543  0.028
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