Steven M. Dubinett - Publications

Affiliations: 
Cellular & Molecular Pathology 049D University of California, Los Angeles, Los Angeles, CA 
Area:
Cell Biology, Molecular Biology, Pathology

283 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Shin DS, Park K, Garon E, Dubinett S. Targeting EZH2 to overcome the resistance to immunotherapy in lung cancer. Seminars in Oncology. PMID 35851153 DOI: 10.1053/j.seminoncol.2022.06.005  0.33
2022 Govindan R, Aggarwal C, Antonia SJ, Davies M, Dubinett SM, Ferris A, Forde PM, Garon EB, Goldberg SB, Hassan R, Hellmann MD, Hirsch FR, Johnson ML, Malik S, Morgensztern D, et al. Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lung cancer and mesothelioma. Journal For Immunotherapy of Cancer. 10. PMID 35640927 DOI: 10.1136/jitc-2021-003956  0.377
2021 Saggese P, Martinez CA, Tran LM, Lim R, Dumitras C, Grogan T, Elashoff D, Ramin SR, Dubinett SM, Liu B, Scafoglio C. Genotoxic Treatment Enhances Immune Response in a Genetic Model of Lung Cancer. Cancers. 13. PMID 34298808 DOI: 10.3390/cancers13143595  0.338
2021 Kadara H, Tran LM, Liu B, Vachani A, Li S, Sinjab A, Zhou XJ, Dubinett SM, Krysan K. Early Diagnosis and Screening for Lung Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 34001525 DOI: 10.1101/cshperspect.a037994  0.391
2021 Sinjab A, Han G, Treekitkarnmongkol W, Hara K, Brennan PM, Dang M, Hao D, Wang R, Dai E, Dejima H, Zhang J, Bogatenkova E, Sanchez-Espiridion B, Chang K, Little DR, ... ... Dubinett SM, et al. Resolving the spatial and cellular architecture of lung adenocarcinoma by multiregion single-cell sequencing. Cancer Discovery. PMID 33972311 DOI: 10.1158/2159-8290.CD-20-1285  0.326
2021 Li R, Salehi-Rad R, Crosson W, Momcilovic M, Lim RJ, Ong SL, Huang ZL, Zhang T, Abascal J, Dumitras C, Jing Z, Park SJ, Krysan K, Shackelford DB, Tran LM, ... ... Dubinett SM, et al. Inhibition of Granulocytic Myeloid-Derived Suppressor Cells Overcomes Resistance to Immune Checkpoint Inhibition in LKB1-deficient Non-Small Cell Lung Cancer. Cancer Research. PMID 33853830 DOI: 10.1158/0008-5472.CAN-20-3564  0.375
2021 Han G, Sinjab A, Hara K, Treekitkarnmongkol W, Brennan P, Chang K, Bogatenkova E, Sanchez-Espiridion B, Behrens C, Solis LM, Gao B, Girard L, Zhang J, Sepesi B, Cascone T, ... ... Dubinett S, et al. Single-Cell Expression Landscape of SARS-CoV-2 Receptor and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients. Cancers. 13. PMID 33809063 DOI: 10.3390/cancers13061250  0.405
2021 Salehi-Rad R, Li R, Tran LM, Lim RJ, Abascal J, Momcilovic M, Park SJ, Ong SL, Shabihkhani M, Huang ZL, Paul M, Shackelford DB, Krysan K, Liu B, Dubinett SM. Novel Kras-mutant murine models of non-small cell lung cancer possessing co-occurring oncogenic mutations and increased tumor mutational burden. Cancer Immunology, Immunotherapy : Cii. PMID 33507343 DOI: 10.1007/s00262-020-02837-9  0.326
2020 Garon EB, Chih-Hsin Yang J, Dubinett SM. The Role of Interleukin 1β in the Pathogenesis of Lung Cancer. Jto Clinical and Research Reports. 1: 100001. PMID 34589908 DOI: 10.1016/j.jtocrr.2020.100001  0.324
2020 Dost AFM, Moye AL, Vedaie M, Tran LM, Fung E, Heinze D, Villacorta-Martin C, Huang J, Hekman R, Kwan JH, Blum BC, Louie SM, Rowbotham SP, Sainz de Aja J, Piper ME, ... ... Dubinett SM, et al. Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells. Cell Stem Cell. PMID 32891189 DOI: 10.1016/J.Stem.2020.07.022  0.498
2020 Lim RJ, Liu B, Krysan K, Dubinett SM. Lung Cancer and Immunity Markers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 32856614 DOI: 10.1158/1055-9965.Epi-20-0716  0.517
2020 Li R, Ong SL, Tran LM, Jing Z, Liu B, Park SJ, Huang ZL, Walser TC, Heinrich EL, Lee G, Salehi-Rad R, Crosson WP, Pagano PC, Paul MK, Xu S, ... ... Dubinett S, et al. Author Correction: Chronic IL-1β-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer. Scientific Reports. 10: 4386. PMID 32127587 DOI: 10.1038/S41598-020-61341-3  0.79
2020 Sharma S, Kadam P, Dubinett S. CCL21 Programs Immune Activity in Tumor Microenvironment. Advances in Experimental Medicine and Biology. 1231: 67-78. PMID 32060847 DOI: 10.1007/978-3-030-36667-4_7  0.372
2020 Salehi-Rad R, Li R, Paul MK, Dubinett SM, Liu B. The Biology of Lung Cancer: Development of More Effective Methods for Prevention, Diagnosis, and Treatment. Clinics in Chest Medicine. 41: 25-38. PMID 32008627 DOI: 10.1016/J.Ccm.2019.10.003  0.522
2020 Li R, Ong SL, Tran LM, Jing Z, Liu B, Park SJ, Huang ZL, Walser TC, Heinrich EL, Lee G, Salehi-Rad R, Crosson WP, Pagano PC, Paul MK, Xu S, ... ... Dubinett S, et al. Chronic IL-1β-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer. Scientific Reports. 10: 377. PMID 31941995 DOI: 10.1038/S41598-019-57285-Y  0.804
2020 Momcilovic M, Jones A, Bailey ST, Waldmann CM, Li R, Lee JT, Abdelhady G, Gomez A, Holloway T, Schmid E, Stout D, Fishbein MC, Stiles L, Dabir DV, Dubinett SM, et al. Publisher Correction: In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer. Nature. PMID 31896820 DOI: 10.1038/S41586-019-1890-Z  0.413
2020 Young PA, Marquez-Garban DC, Goodglick L, Noor ZS, Moatamed N, Elashoff D, Grogan T, Romero T, Sasano H, Saito R, Rausch R, Hamilton N, Dubinett SM, Garon E, Pietras RJ. SUN-125 Phase Ib Study of Dual Therapy with an Aromatase Inhibitor Exemestane and Carboplatin-Based Therapy for Postmenopausal Women with Advanced Non-Small Cell Lung Cancer Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.695  0.402
2020 Koziolek EJ, Martin D, Liu J, Barrio JR, Wallace WD, Shackelford DB, Yanagawa J, Dubinett S, Scafoglio C. Abstract A46: A novel patient-derived approach for preclinical evaluation of predictive imaging biomarkers in early lung cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-A46  0.414
2020 Li R, Salehi-Rad R, Momcilovic M, Ong S, Lim R, Huang ZL, Tran L, Jing Z, Paul M, Teitell M, Minna J, Shackelford D, Kostyantyn K, Liu B, Dubinett S. Abstract 1016: Inhibition of chemokine-induced myeloid cells potentiates the anti-PD-1 response in KRAS/LKB1 mutant non-small cell lung cancer Immunology. DOI: 10.1158/1538-7445.Am2020-1016  0.466
2020 Garon EB, Chih-Hsin Yang J, Dubinett SM. The Role of Interleukin 1β in the Pathogenesis of Lung Cancer Jto Clinical and Research Reports. 1: 100001. DOI: 10.1016/j.jtocrr.2020.100001  0.365
2020 Momcilovic M, Han M, Bushong E, Stiles L, Dubinett S, Christofk H, Shirihai O, Koehler C, Sadeghi S, Ellisman M, Shackelford D. IA08 Mapping Mitochondrial Heterogeneity in Lung Cancer Journal of Thoracic Oncology. 15: S4. DOI: 10.1016/J.Jtho.2019.12.009  0.402
2019 Li R, Dubinett SM. Myeloid-derived suppressor cell-dependent inhibition of B cell responses in non-small cell lung cancer. Translational Lung Cancer Research. 8: S331-S333. PMID 32038908 DOI: 10.21037/Tlcr.2019.04.10  0.412
2019 Momcilovic M, Jones A, Bailey ST, Waldmann CM, Li R, Lee JT, Abdelhady G, Gomez A, Holloway T, Schmid E, Stout D, Fishbein MC, Stiles L, Dabir DV, Dubinett SM, et al. In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer. Nature. PMID 31666695 DOI: 10.1038/S41586-019-1715-0  0.358
2019 Krysan K, Tran LM, Grimes BS, Fishbein GA, Seki A, Gardner BK, Walser TC, Salehi-Rad R, Yanagawa J, Lee JM, Sharma S, Aberle D, Spira AE, Elashoff DA, Wallace WD, ... ... Dubinett SM, et al. The immune contexture associates with the genomic landscape in lung adenomatous premalignancy. Cancer Research. PMID 31142513 DOI: 10.1158/0008-5472.Can-19-0153  0.433
2019 Hu-Lieskovan S, Lisberg A, Zaretsky JM, Grogan TR, Rizvi H, Wells DK, Carroll J, Cummings A, Madrigal J, Jones B, Gukasyan J, Shintaku IP, Slamon DJ, Dubinett SM, Goldman JW, et al. Tumor characteristics associated with benefit from pembrolizumab in advanced non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31113840 DOI: 10.1158/1078-0432.Ccr-18-4275  0.437
2019 Beane JE, Mazzilli SA, Campbell JD, Duclos G, Krysan K, Moy C, Perdomo C, Schaffer M, Liu G, Zhang S, Liu H, Vick J, Dhillon SS, Platero SJ, Dubinett SM, et al. Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions. Nature Communications. 10: 1856. PMID 31015447 DOI: 10.1038/S41467-019-09834-2  0.418
2019 Salehi-Rad R, Dubinett SM. Understanding the mechanisms of immune-evasion by lung cancer in the context of chronic inflammation in emphysema. Journal of Thoracic Disease. 11: 382-385. PMID 30962980 DOI: 10.21037/Jtd.2019.01.22  0.466
2019 Kadara H, Sivakumar S, Jakubek Y, San Lucas FA, Lang W, McDowell T, Weber Z, Behrens C, Davies GE, Kalhor N, Moran C, El-Zein R, Mehran R, Swisher SG, Wang J, ... ... Dubinett S, et al. Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer. American Journal of Respiratory and Critical Care Medicine. PMID 30896962 DOI: 10.1164/Rccm.201806-1178Oc  0.454
2019 Zhang J, Burks E, Beane J, Sullivan T, Liu G, Dubinett S, Lenburg M, Spira A. Abstract 3530: Gene expression alterations associated with histologic aggressiveness in stage I lung adenocarcinomas Cancer Research. 79: 3530-3530. DOI: 10.1158/1538-7445.Sabcs18-3530  0.46
2019 Liu B, Garon EB, Lisberg AE, Salehi-Rad R, Lee JM, Tran LM, Krysan K, Li R, Lim RJ, Paul M, Lin Y, Jing Z, Abtin F, Suh RD, Oh S, ... ... Dubinett SM, et al. Abstract CT226: A Phase I trial ofin situvaccination with autologousCCL21-modified dendritic cells (CCL21-DC) combined with pembrolizumab for advanced NSCLC Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Ct226  0.365
2019 Villegas B, Koziolek E, Liu J, Wallace WD, Elashoff D, Aberle DR, Shackelford DB, Barrio JR, Yanagawa J, Dubinett SM, Scafoglio C. Abstract 4224: SGLT2 is a diagnostic target for early stage lung adenocarcinoma Cancer Research. 79: 4224-4224. DOI: 10.1158/1538-7445.Am2019-4224  0.426
2019 Li R, Salehi-Rad R, Ong S, Momcilovic M, Liu B, Lim R, Tran L, Huang Z, Jing Z, Paul M, Krysan K, Park S, Minna J, Teitell M, Shackelford D, ... Dubinett S, et al. Abstract 2710: Depletion of CXCR2-dependent myeloid-derived suppressor cells (MDSCs) overcomes anti-PD-1 resistance in a murine model of LKB1-deficient non-small cell lung cancer (NSCLC) with high mutational load Cancer Research. 79: 2710-2710. DOI: 10.1158/1538-7445.Am2019-2710  0.452
2019 Paul MK, Basu A, Bisht B, Pagano P, Fontebasso Y, Krysan K, Tran L, Alioscha-Perez M, Minna J, DiCarlo D, Sahli H, Weiss S, Dubinett SM. Abstract 1030: Regulation and role of actin dynamics in promoting premalignant cell migration Cancer Research. 79: 1030-1030. DOI: 10.1158/1538-7445.Am2019-1030  0.361
2019 Zhang J, Burks E, Sullivan T, Sands J, Regis S, Mckee B, Mckee A, Zhang S, Liu H, Liu G, Dubinett S, Spira A, Beane J, Christ K, Lenburg M. MA15.06 Stage I Lung Adenocarcinoma Gene Expression Associated with Aggressive Histologic Features for Guiding Precision Surgery and Therapy Journal of Thoracic Oncology. 14: S310-S311. DOI: 10.1016/J.Jtho.2019.08.623  0.368
2018 Scafoglio CR, Villegas B, Abdelhady G, Bailey ST, Liu J, Shirali AS, Wallace WD, Magyar CE, Grogan TR, Elashoff D, Walser T, Yanagawa J, Aberle DR, Barrio JR, Dubinett SM, et al. Sodium-glucose transporter 2 is a diagnostic and therapeutic target for early-stage lung adenocarcinoma. Science Translational Medicine. 10. PMID 30429355 DOI: 10.1126/Scitranslmed.Aat5933  0.451
2018 Dhar M, Lam JN, Walser T, Dubinett SM, Rettig MB, Di Carlo D. Functional profiling of circulating tumor cells with an integrated vortex capture and single-cell protease activity assay. Proceedings of the National Academy of Sciences of the United States of America. PMID 30224472 DOI: 10.1073/Pnas.1803884115  0.345
2018 Garon EB, Siegfried JM, Stabile LP, Young PA, Marquez-Garban DC, Park DJ, Patel R, Hu EH, Sadeghi S, Parikh RJ, Reckamp KL, Adams B, Elashoff RM, Elashoff D, Grogan T, ... ... Dubinett SM, et al. Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 123: 91-98. PMID 30089602 DOI: 10.1016/J.Lungcan.2018.06.013  0.456
2018 Brahmer JR, Govindan R, Anders RA, Antonia SJ, Sagorsky S, Davies MJ, Dubinett SM, Ferris A, Gandhi L, Garon EB, Hellmann MD, Hirsch FR, Malik S, Neal JW, Papadimitrakopoulou VA, et al. The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of non-small cell lung cancer (NSCLC). Journal For Immunotherapy of Cancer. 6: 75. PMID 30012210 DOI: 10.1186/S40425-018-0382-2  0.47
2018 Chattopadhyay A, Yang X, Mukherjee P, Sulaiman D, Fogelman HR, Grijalva V, Dubinett S, Wasler TC, Paul MK, Salehi-Rad R, Mack JJ, Iruela-Arispe ML, Navab M, Fogelman AM, Reddy ST. Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer. Scientific Reports. 8: 9032. PMID 29899427 DOI: 10.1038/S41598-018-26755-0  0.506
2018 Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Braas D, Go J, Graeber TG, Parlati F, Demo S, Li R, Walser TC, Gricowski M, Shuman R, Ibarra J, Fridman D, ... ... Dubinett SM, et al. The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma. Cancer Cell. 33: 905-921.e5. PMID 29763624 DOI: 10.1016/J.Ccell.2018.04.002  0.413
2018 Salehi-Rad R, Dubinett SM. Understanding the Hurdles in Lung Cancer Immunotherapy in the Context of Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 29589957 DOI: 10.1164/Rccm.201803-0523Ed  0.435
2018 Walser TC, Jing Z, Tran LM, Lin YQ, Yakobian N, Wang G, Krysan K, Zhu LX, Sharma S, Lee MH, Belperio JA, Ooi AT, Gomperts BN, Shay JW, Larsen JE, ... ... Dubinett SM, et al. Silencing the Snail-dependent RNA splice regulator ESRP1 drives malignant transformation of human pulmonary epithelial cells. Cancer Research. PMID 29431637 DOI: 10.1158/0008-5472.Can-17-0315  0.488
2018 Lu H, Cummings AL, Goldman JW, Lisberg AE, Hu-Lieskovan S, Grogan T, Gukasyan J, Madrigal J, Carroll JM, Bornazyan K, Jones B, Noor ZS, Zaretsky JM, Elashoff D, Slamon DJ, ... Dubinett SM, et al. Human leukocyte antigen (HLA) B44 supertype and immunotherapy outcomes in non-small cell lung cancer (NSCLC). Journal of Clinical Oncology. 36: 3026-3026. DOI: 10.1200/Jco.2018.36.15_Suppl.3026  0.346
2018 Krysan K, Tran LM, Grimes BS, Dubinett SM. Abstract IA09: Inflammation and immunity in pulmonary premalignancy Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-Ia09  0.439
2018 Husain H, Dietrich M, Dubinett S, Gerber DE, Gregg J, Shiller M, West H, Thai K, Milner A, Chehab N, Baik C. Abstract B32: RADIANCE: An open-label, nonrandomized, prospective biomarker study to assess analytic concordance between noninvasive testing and tissue testing for EGFR T790M mutation detection in patients with non-small cell lung cancer Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-B32  0.378
2018 Momcilovic M, Bailey ST, Lee JT, Magyar C, Braas D, Graeber T, Parlati F, Demo S, Krysan K, Walser TC, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. Abstract B28: Targeted inhibition of EGFR and glutaminase induces metabolic crisis in EGFR-mutant lung cancer Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-B28  0.477
2018 Yanagawa J, Fung E, Lee M, Wallace WD, Fishbein MC, Paul M, Krysan K, Minna JD, Guo R, Elashoff D, Lee JM, Dubinett SM. Abstract B20: Premalignant lung lesions demonstrate enhanced PD-L1 upregulation in response to interferon-gamma exposure Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-B20  0.44
2018 Scafoglio C, Bailey ST, Abdelhady G, Liu J, Yanagawa J, Shirali A, Wallace DW, Barrio JR, Wright EM, Walser T, Dubinett SM, Shackelford DB. Abstract A16: Sodium-dependent glucose transporter 2 is a novel diagnostic and therapeutic target for early-stage lung adenocarcinoma Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-A16  0.393
2018 Sivakumar S, Jakubek Y, Lucas FAS, Lang W, McDowell C, Weber Z, Behrens C, Kalhor N, Moran C, El-Zein R, Davies G, Fujimoto J, Mehran R, Swisher SG, Wang J, ... ... Dubinett S, et al. Abstract 3997: Somatic mutational processes in the cancerization field of the normal-appearing airway reveal early drivers in the development of non-small cell lung cancer Tumor Biology. DOI: 10.1158/1538-7445.Am2018-3997  0.471
2018 Paul MK, Dutta S, Bisht B, Ramin S, Pagano P, Bitan G, Minna JD, Dubinett SM. Abstract 2015: Exosomes secreted by highly migratory premalignant lung epithelial cells promote epithelial mesenchymal transition and migration Cancer Research. 78: 2015-2015. DOI: 10.1158/1538-7445.Am2018-2015  0.486
2018 Cummings A, Lu H, Gukasyan J, Madrigal J, Carroll J, Bornazyan K, Jones B, Noor Z, Lisberg A, Goldman J, Hu-Lieskovan S, Dubinett S, Garon E. P1.04-14 HLA B44 Supertype Associated with Less Favorable Neoantigen Binding in Non-Small Cell Lung Cancer Treated with Immunotherapy Journal of Thoracic Oncology. 13: S530-S531. DOI: 10.1016/J.Jtho.2018.08.729  0.448
2017 Dubinett SM, Spira AE. Impact of COPD on Immune-based Treatment for Lung Cancer: Moving Towards Disease Interception. American Journal of Respiratory and Critical Care Medicine. PMID 29072842 DOI: 10.1164/Rccm.201710-2065Ed  0.446
2017 Sivakumar S, San Lucas FA, McDowell TL, Lang W, Xu L, Fujimoto J, Zhang J, Futreal PA, Fukuoka J, Yatabe Y, Dubinett SM, Spira AE, Fowler J, Hawk ET, Wistuba II, et al. Genomic landscape of atypical adenomatous hyperplasia reveals divergent modes to lung adenocarcinoma. Cancer Research. PMID 28951454 DOI: 10.1158/0008-5472.Can-17-1605  0.437
2017 Pavel AB, Campbell JD, Liu G, Elashoff DA, Dubinett SM, Smith K, Whitney D, Lenburg ME, Spira AE. Alterations in bronchial airway microRNA expression for lung cancer detection. Cancer Prevention Research (Philadelphia, Pa.). PMID 28877936 DOI: 10.1158/1940-6207.Capr-17-0098  0.459
2017 Pagano PC, Tran LM, Bendris N, O'Byrne S, Tse HT, Sharma S, Hoech JW, Park SJ, Liclican EL, Jing Z, Li R, Krysan K, Paul MK, Fontebasso Y, Larsen JE, ... ... Dubinett SM, et al. Identification of a human airway epithelial cell subpopulation with altered biophysical, molecular, and metastatic properties. Cancer Prevention Research (Philadelphia, Pa.). PMID 28754664 DOI: 10.1158/1940-6207.Capr-16-0335  0.472
2017 Lee JMM, Lee MH, Garon E, Goldman JW, Salehi-Rad R, Baratelli FE, Schaue D, Wang G, Rosen F, Yanagawa J, Walser TC, Lin Y, Park SJ, Adams S, Marincola FM, ... ... Dubinett SM, et al. Phase I trial of intratumoral injection of CCL21 gene modified dendritic cells in lung cancer elicits tumor-specific immune responses and CD8+ T cell infiltration. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28468947 DOI: 10.1158/1078-0432.Ccr-16-2821  0.435
2017 Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Magyar C, Braas D, Graeber T, Jackson NJ, Czernin J, Emberley E, Gross M, Janes J, Mackinnon A, Pan A, Rodriguez M, ... ... Dubinett SM, et al. Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer. Cell Reports. 18: 601-610. PMID 28099841 DOI: 10.1016/J.Celrep.2016.12.061  0.454
2017 Sharma S, Dubinett S. Inhibiting C5a/C5aR axis reduces myeloid-derived suppressor cells and enhances PD-1 blockade therapy in lung cancer Translational Cancer Research. 6. DOI: 10.21037/13966  0.523
2017 Campbell J, Zhang X, Dhillon SS, Perdomo C, Mazzilli S, Geshalter Y, Liu G, Zhang S, Lin H, Vick J, Moy C, Monti S, Johnson E, Meyerson M, Dubinett S, et al. Abstract 3259: The genomic landscape of premalignant lung squamous cell carcinoma lesions Cancer Research. 77: 3259-3259. DOI: 10.1158/1538-7445.Am2017-3259  0.381
2017 Momcilovic M, Bailey ST, Lee JT, Braas D, Graeber TG, Works M, Parlati F, Demo S, Walser TC, Dubinett SM, Sadeghi S, Christofk H, Shackelford DB. Abstract 1830: Targeted inhibition of EGFR and glutaminase induces metabolic crisis in EGFR mutant lung cancer Cancer Research. 77: 1830-1830. DOI: 10.1158/1538-7445.Am2017-1830  0.478
2017 Sivakumar S, San Lucas F, McDowell T, Lang W, Xu L, Fujimoto J, Zhang J, Wistuba I, Futreal F, Fukuoka J, Yatabe Y, Dubinett S, Spira A, Fowler J, Hawk E, et al. Genomic Landscape of Atypical Adenomatous Hyperplasia and Their Progression to Lung Adenocarcinomas Journal of Thoracic Oncology. 12: S1546. DOI: 10.1016/J.Jtho.2017.06.061  0.401
2017 Salehi-Rad R, Walser T, Ong S, Park S, Sharma S, Jay L, Dubinett S. CCL21 Combined with PD-1 Blockade Cooperatively Inhibits Tumor Growth in KRAS Murine Model of NSCLC Journal of Thoracic Oncology. 12: S1537. DOI: 10.1016/J.Jtho.2017.06.026  0.319
2017 Lee J, Garon E, Goldman J, Abtin F, Suh R, Wallace W, Zeng G, Elashoff D, Sharma S, Dubinett S. Phase I Trial of CCL21 Gene Modified Dendritic Cells in Lung Cancer Elicits Immune Responses Journal of Thoracic Oncology. 12: S1537. DOI: 10.1016/J.Jtho.2017.06.024  0.441
2017 Lisberg A, Mckenna R, Dering J, Chen H, Kamranpour N, Hou D, Velez M, Cameron R, Lee J, Dubinett S, Slamon D. P1.05-003 Coexpression of CD8a and PD-L1 Frequently Observed in Resected NSCLC Tumors from Smokers Journal of Thoracic Oncology. 12: S614-S615. DOI: 10.1016/J.Jtho.2016.11.787  0.301
2017 Lisberg A, Mckenna R, Dering J, Chen H, Hou D, Kamranpour N, Velez M, Cameron R, Lee J, Dubinett S, Slamon D. P2.01-078 Frequent High TIM-3 (HAVCR2) Expression in Resected NSCLC Specimens, Most Notably in Adenocarcinoma Histology Journal of Thoracic Oncology. 12: S835. DOI: 10.1016/J.Jtho.2016.11.1130  0.339
2016 Arenberg D, Dubinett SM. Lung Cancer: Evolving Concepts in Management. Seminars in Respiratory and Critical Care Medicine. 37: 647-648. PMID 27732986 DOI: 10.1055/S-0036-1592297  0.443
2016 Lin Y, Mallen-St Clair J, Wang G, Luo J, Palma-Diaz F, Lai C, Elashoff DA, Sharma S, Dubinett SM, St John M. p38 MAPK mediates epithelial-mesenchymal transition by regulating p38IP and Snail in head and neck squamous cell carcinoma. Oral Oncology. 60: 81-9. PMID 27531877 DOI: 10.1016/J.Oraloncology.2016.06.010  0.331
2016 Hong CS, Graham NA, Gu W, Espindola Camacho C, Mah V, Maresh EL, Alavi M, Bagryanova L, Krotee PA, Gardner BK, Behbahan IS, Horvath S, Chia D, Mellinghoff IK, Hurvitz SA, ... Dubinett SM, et al. MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. Cell Reports. PMID 26876179 DOI: 10.1016/J.Celrep.2016.01.057  0.427
2016 Grimes BS, Krysan K, Tran LM, Park SJ, Aberle DR, Spira AE, Dubinett SM. Indolence versus aggression in non-small cell lung cancer: defining heterogeneity to impact clinical outcomes Translational Cancer Research. 5. DOI: 10.21037/11283  0.446
2016 Walser TC, Jing Z, Tran L, Lin Y, Zhu L, Sharma S, Ooi A, Gomperts BN, Shay JW, Larsen JE, Gao B, Minna JD, Fishbein MC, Dubinett SM. Abstract 5170: Snail-dependent ESRP1 silencing drives malignant conversion of human pulmonary epithelial cells Cancer Research. 76: 5170-5170. DOI: 10.1158/1538-7445.Am2016-5170  0.35
2016 Moses E, Wang T, Jackson GR, Corbett S, Drizik E, Brooks D, O’Connor G, Perdomo C, Dubinett S, Hayden P, Lenburg ME, Spira A. Abstract 4502: Molecular impact of in vitro exposure to electronic cigarette vapor in human bronchial epithelium Cancer Research. 76: 4502-4502. DOI: 10.1158/1538-7445.Am2016-4502  0.319
2016 Lee M, Yanagawa J, Walser TC, Goldman JW, Garon EB, Zeng G, Sharma S, Gao B, Minna J, Dubinett SM, Lee JM. Abstract 2324: FRA1 contributes to ERK-mediated increased PD-L1 expression in KRAS mutated premalignant human bronchial epithelial cells Cancer Research. 76: 2324-2324. DOI: 10.1158/1538-7445.Am2016-2324  0.344
2016 Pavel AB, Campbell J, Liu G, Zhang S, Liu H, Xiao J, Porta K, Whitney D, Dubinett S, Elashoff D, Lenburg M, Spira A. Abstract 1954: microRNA expression in bronchial epithelium for lung cancer detection Cancer Research. 76: 1954-1954. DOI: 10.1158/1538-7445.Am2016-1954  0.419
2016 Salehi-rad R, Walser TC, Yakobian N, Park SJ, Lee M, Lee JM, Sharma S, Dubinett SM. Intratumoral CCL21 and checkpoint blockade cooperatively inhibit NSCLC tumor growth in vivo to a greater extent than either monotherapy alone Journal of Thoracic Oncology. 11: S41. DOI: 10.1016/J.Jtho.2015.12.069  0.498
2016 Li R, Ong S, Krysan K, Tran L, Park S, Walser T, Zhe J, Dubinett S. An epigenetic switch leads to EMT memory in chronic inflammation in non-small cell lung cancer Journal of Thoracic Oncology. 11: S30-S31. DOI: 10.1016/J.Jtho.2015.12.051  0.467
2016 Grimes BS, Walser TC, Li R, Jing Z, Tran L, Dubinett SM. The transcription factor Slug induces diverse malignant phenotypes in models of established lung cancer and pulmonary premalignancy Journal of Thoracic Oncology. 11: S22. DOI: 10.1016/J.Jtho.2015.12.036  0.463
2015 Momcilovic M, McMickle R, Abt E, Seki A, Simko SA, Magyar C, Stout DB, Fishbein MC, Walser TC, Dubinett SM, Shackelford DB. Heightening Energetic Stress Selectively Targets LKB1-Deficient Non-Small Cell Lung Cancers. Cancer Research. 75: 4910-22. PMID 26574479 DOI: 10.1158/0008-5472.Can-15-0797  0.515
2015 Lin Y, Clair JM, Luo J, Sharma S, Dubinett S, John MS. p53 modulates NF-κB mediated epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma. Oral Oncology. PMID 26306422 DOI: 10.1016/J.Oraloncology.2015.07.006  0.312
2015 Zhu LX, Davoodi M, Srivastava MK, Kachroo P, Lee JM, St John M, Harris-White M, Huang M, Strieter RM, Dubinett S, Sharma S. GITR agonist enhances vaccination responses in lung cancer. Oncoimmunology. 4: e992237. PMID 26137407 DOI: 10.4161/2162402X.2014.992237  0.455
2015 Reckamp KL, Koczywas M, Cristea MC, Dowell JE, Wang HJ, Gardner BK, Milne GL, Figlin RA, Fishbein MC, Elashoff RM, Dubinett SM. Randomized phase 2 trial of erlotinib in combination with high-dose celecoxib or placebo in patients with advanced non-small cell lung cancer. Cancer. PMID 26033830 DOI: 10.1002/Cncr.29480  0.453
2015 Lee M, Yanagawa J, Li R, Walser TC, Krysan K, Wang G, Goldman JW, Garon EBG, Zeng G, Sharma S, Minna JD, Carbone D, Dubinett SM, Lee JM. Increased PD-L1 expression in KRAS mutated premalignant human bronchial epithelial cells is enhanced by LKB1 loss and mediated by ERK activation Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P305  0.404
2015 Park SJ, Walser TC, Tran LM, Perdomo C, Wang T, Hong L, Pagano PC, Liclican EL, Larsen JE, Krysan K, Fishbein MC, Minna JD, Lenburg ME, Avrum S, Dubinett S. Abstract B22: The role of e-cigarette exposure on pulmonary epithelial cell transformation Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-B22  0.431
2015 Pavel AB, Campbell JD, Liu G, Zhang S, Liu H, Luo L, Xiao J, Porta K, Whitney D, Dubinett S, Elashoff D, Lenburg ME, Spira A. Abstract 3077: Dysregulation of microRNA-mRNA regulatory networks in the bronchial airway epithelium of smokers with lung cancer Cancer Research. 75: 3077-3077. DOI: 10.1158/1538-7445.Am2015-3077  0.472
2014 Lee MH, Kachroo P, Pagano PC, Yanagawa J, Wang G, Walser TC, Krysan K, Sharma S, John MS, Dubinett SM, Lee JM. Combination Treatment with Apricoxib and IL-27 Enhances Inhibition of Epithelial-Mesenchymal Transition in Human Lung Cancer Cells through a STAT1 Dominant Pathway. Journal of Cancer Science & Therapy. 6: 468-477. PMID 26523208 DOI: 10.4172/1948-5956.1000310  0.489
2014 Liclican EL, Walser TC, Hazra S, Krysan K, Park SJ, Pagano PC, Gardner BK, Larsen JE, Minna JD, Dubinett SM. Loss of miR125a expression in a model of K-ras-dependent pulmonary premalignancy. Cancer Prevention Research (Philadelphia, Pa.). 7: 845-55. PMID 24913817 DOI: 10.1158/1940-6207.Capr-14-0063  0.342
2014 Lin Y, Luo J, Zhu WE, Srivastava M, Schaue D, Elashoff DA, Dubinett SM, Sharma S, Wu B, St John MA. A cytokine-delivering polymer is effective in reducing tumor burden in a head and neck squamous cell carcinoma murine model. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 151: 447-53. PMID 24825873 DOI: 10.1177/0194599814533775  0.319
2014 Ooi AT, Gower AC, Zhang KX, Vick JL, Hong L, Nagao B, Wallace WD, Elashoff DA, Walser TC, Dubinett SM, Pellegrini M, Lenburg ME, Spira A, Gomperts BN. Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). 7: 487-95. PMID 24618292 DOI: 10.1158/1940-6207.Capr-13-0372  0.431
2014 Hanas JS, Peyton MD, Lerner MR, Lightfoot SA, Deb SJ, Hanas RJ, Vu NT, Kupiec TC, Stowell DE, Brackett DJ, Dubinett SM, Hocker JR. Distinguishing patients with stage I lung cancer versus control individuals using serum mass profiling. Cancer Investigation. 32: 136-43. PMID 24579933 DOI: 10.3109/07357907.2014.883528  0.469
2014 Krysan K, Kusko R, Grogan T, O'Hearn J, Reckamp KL, Walser TC, Garon EB, Lenburg ME, Sharma S, Spira AE, Elashoff D, Dubinett SM. PGE2-driven expression of c-Myc and oncomiR-17-92 contributes to apoptosis resistance in NSCLC. Molecular Cancer Research : McR. 12: 765-74. PMID 24469837 DOI: 10.1158/1541-7786.Mcr-13-0377  0.415
2014 Garon EB, Christofk HR, Hosmer W, Britten CD, Bahng A, Crabtree MJ, Hong CS, Kamranpour N, Pitts S, Kabbinavar F, Patel C, von Euw E, Black A, Michelakis ED, Dubinett SM, et al. Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer. Journal of Cancer Research and Clinical Oncology. 140: 443-52. PMID 24442098 DOI: 10.1007/S00432-014-1583-9  0.492
2014 Grant JL, Fishbein MC, Hong LS, Krysan K, Minna JD, Shay JW, Walser TC, Dubinett SM. A novel molecular pathway for Snail-dependent, SPARC-mediated invasion in non-small cell lung cancer pathogenesis. Cancer Prevention Research (Philadelphia, Pa.). 7: 150-60. PMID 24253315 DOI: 10.1158/1940-6207.Capr-13-0263  0.75
2014 Jiwani A, Maple E, Schnall M, Mahon I, Apgar C, Browning R, More K, Morris M, Parrish J, Atwood C, Battaile J, Garshick E, Gatsonis C, Goldstein R, Kieth R, ... ... Dubinett S, et al. Detection and Validation of Molecular Biomarkers for the Early Detection of Lung Cancer Among Military and Veteran Populations: The DECAMP Consortium Chest. 146: 590A. DOI: 10.1378/Chest.1993874  0.391
2014 Park SJ, Walser TC, Perdomo C, Wang T, Hong L, Pagano PC, Liclican EL, Krysan K, Larsen JE, Fishbein MC, Minna JD, Lenburg ME, Spira A, Dubinett SM. Abstract 932: The impact of e-cigarette exposure on pulmonary epithelium gene expression and transformation Cancer Research. 74: 932-932. DOI: 10.1158/1538-7445.Am2014-932  0.443
2014 Wong DJ, Garon EB, Silveira DD, Kamranpour N, Pitts S, Chalukya M, Hamidi H, Dubinett S, Linnartz R, Finn RS, Slamon DJ. Abstract 743: Potent anti-tumor activity of the MEK1/2 inhibitor MEK162 in human non-small cell lung cancer (NSCLC) and squamous cell carcinoma of the head and neck (SCCHN) cell lines Cancer Research. 74: 743-743. DOI: 10.1158/1538-7445.Am2014-743  0.48
2014 Kusko R, Anderlind C, Wang G, Zhang S, Wallace WD, Wasler T, Ebright M, Garcia MM, Eisenberg R, Lee G, Liu G, Elashoff D, Kalhor N, Moran C, Mehran R, ... ... Dubinett S, et al. Abstract 2352: Mapping the airway-wide molecular field of injury in smokers with lung cancer Cancer Research. 74: 2352-2352. DOI: 10.1158/1538-7445.Am2014-2352  0.513
2014 Pavel A, Campbell J, Liu G, Zhang S, Liu H, Dubinett S, Elashoff D, Porta K, Whitney D, Lenburg M, Spira A. Abstract 1485: Biomarker development for lung cancer diagnosis using integrative microRNA and gene expression networks Cancer Research. 74: 1485-1485. DOI: 10.1158/1538-7445.Am2014-1485  0.402
2014 Lin Y, Luo J, Abemayor E, Sharma S, Dubinett S, John MS. Abstract 1141: p53-dependent regulation of epithelial-to-mescenchymal transition by nf-κb in head and neck squamous cell carcinoma Cancer Research. 74: 1141-1141. DOI: 10.1158/1538-7445.Am2014-1141  0.397
2014 Pagano PC, Sharma S, O'Byrne S, Tse HT, Park SJ, Liclican EL, Krysan K, Walser TC, Larsen JE, Minna JD, Gimzewski JK, Carlo DD, Dubinett SM. Abstract B15: Cell motility and deformability in the pathogenesis of lung cancer. Clinical Cancer Research. 20: B15-B15. DOI: 10.1158/1078-0432.14Aacriaslc-B15  0.534
2014 Lee J, Garon E, Lee M, Baratelli F, Wang G, Abtin F, Suh R, Wallace W, Zeng G, Sharma S, Dubinett S. Phase I Trial of Trans-thoracic Injection of CCL21 Gene Modified Dendritic Cells in Human Non-small Cell Lung Carcinoma Journal of Surgical Research. 186: 558. DOI: 10.1016/J.Jss.2013.11.470  0.422
2013 Sharma S, Zhu L, Srivastava MK, Harris-White M, Huang M, Lee JM, Rosen F, Lee G, Wang G, Kickhoefer V, Rome LH, Baratelli F, St John M, Reckamp K, Chul-Yang S, ... ... Dubinett S, et al. CCL21 Chemokine Therapy for Lung Cancer. International Trends in Immunity. 1: 10-15. PMID 25264541  0.365
2013 Kachroo P, Lee MH, Zhang L, Baratelli F, Lee G, Srivastava MK, Wang G, Walser TC, Krysan K, Sharma S, Dubinett SM, Lee JM. IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer. Journal of Experimental & Clinical Cancer Research : Cr. 32: 97. PMID 24274066 DOI: 10.1186/1756-9966-32-97  0.491
2013 Perdomo C, Campbell JD, Gerrein J, Tellez CS, Garrison CB, Walser TC, Drizik E, Si H, Gower AC, Vick J, Anderlind C, Jackson GR, Mankus C, Schembri F, O'Hara C, ... ... Dubinett SM, et al. MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 18946-51. PMID 24158479 DOI: 10.1073/Pnas.1220319110  0.489
2013 Dubinett SM, Spira A. Challenge and opportunity of targeted lung cancer chemoprevention. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 4169-71. PMID 24002497 DOI: 10.1200/Jco.2013.51.2400  0.502
2013 Ohashi K, Sequist LV, Arcila ME, Lovly CM, Chen X, Rudin CM, Moran T, Camidge DR, Vnencak-Jones CL, Berry L, Pan Y, Sasaki H, Engelman JA, Garon EB, Dubinett SM, et al. Characteristics of lung cancers harboring NRAS mutations. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 2584-91. PMID 23515407 DOI: 10.1158/1078-0432.Ccr-12-3173  0.479
2013 Sharma S, Zhu L, Davoodi M, Harris-White M, Lee JM, St John M, Salgia R, Dubinett S. TLR3 agonists and proinflammatory antitumor activities. Expert Opinion On Therapeutic Targets. 17: 481-3. PMID 23506058 DOI: 10.1517/14728222.2013.781585  0.324
2013 Garon EB, Finn RS, Hamidi H, Dering J, Pitts S, Kamranpour N, Desai AJ, Hosmer W, Ide S, Avsar E, Jensen MR, Quadt C, Liu M, Dubinett SM, Slamon DJ. The HSP90 inhibitor NVP-AUY922 potently inhibits non-small cell lung cancer growth. Molecular Cancer Therapeutics. 12: 890-900. PMID 23493311 DOI: 10.1158/1535-7163.Mct-12-0998  0.444
2013 Garon EB, Pietras RJ, Finn RS, Kamranpour N, Pitts S, Márquez-Garbán DC, Desai AJ, Dering J, Hosmer W, von Euw EM, Dubinett SM, Slamon DJ. Antiestrogen fulvestrant enhances the antiproliferative effects of epidermal growth factor receptor inhibitors in human non-small-cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 8: 270-8. PMID 23399957 DOI: 10.1097/Jto.0B013E31827D525C  0.435
2013 Gomperts BN, Walser TC, Spira A, Dubinett SM. Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer. Cancer Prevention Research (Philadelphia, Pa.). 6: 4-7. PMID 23233734 DOI: 10.1158/1940-6207.Capr-12-0470  0.486
2013 Park SJ, Walser TC, Perdomo C, Pagano PP, Brass D, Liclican EL, Krysan K, Lenburg ME, Spira A, Dubinett SM. Abstract C58: The gene expression and functional impact of E-cigarette exposure on pulmonary epithelial transformation Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-C58  0.381
2013 Liclican EL, Hazra S, Larsen JE, Park SJ, Pagano PC, Walser TC, Krysan K, Minna JD, Dubinett SM. Abstract A08: The role of miR-125a in the pathogenesis of lung cancer Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-A08  0.383
2013 Garon EB, Siegfried JM, Dubinett SM, Elashoff RM, Park DJ, Parikh RJ, Patel R, Hu EH, Reckamp KL, Adams B, Martinez D, Wang H, Kabbinavar F, Dacic S, Brennan M, et al. Abstract 4664: Result of TORI L-03, a randomized, multicenter phase II clinical trial of erlotinib (E) or E + fulvestrant (F) in previously treated advanced non-small cell lung cancer (NSCLC). Cancer Research. 73: 4664-4664. DOI: 10.1158/1538-7445.Am2013-4664  0.405
2013 Ooi AT, Gower A, Zhang K, Vick J, Hong L, Fishbein M, Nagao B, Wallace WD, Elashoff D, Lenburg M, Dubinett S, Spira A, Gomperts B. Abstract 1063: Examining early events in carcinogenesis by profiling premalignant lesions in the airways of patients with lung squamous cell carcinomas. Cancer Research. 73: 1063-1063. DOI: 10.1158/1538-7445.Am2013-1063  0.508
2013 Li R, Walser TC, Krysan K, Shackelford D, Larsen JE, Minna JD, Dubinett SM. Abstract C296: The contribution of LKB1/STK11-mediated CXCL8 dysregulation to lung carcinogenesis. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C296  0.56
2012 Srivastava MK, Zhu L, Harris-White M, Huang M, St John M, Lee JM, Salgia R, Cameron RB, Strieter R, Dubinett S, Sharma S. Targeting myeloid-derived suppressor cells augments antitumor activity against lung cancer. Immunotargets and Therapy. 2012: 7-12. PMID 24791250 DOI: 10.2147/ITT.S32617  0.381
2012 Srivastava MK, Dubinett S, Sharma S. Targeting MDSCs enhance therapeutic vaccination responses against lung cancer. Oncoimmunology. 1: 1650-1651. PMID 23264925 DOI: 10.4161/Onci.21970  0.477
2012 Sharma S, Dubinett S, Salgia R. CD14(+)S100A9(+) myeloid-derived suppressor cells portend decreased survival in patients with advanced lung cancer. American Journal of Respiratory and Critical Care Medicine. 186: 940-1. PMID 23155211 DOI: 10.1164/Rccm.201209-1597Ed  0.463
2012 Lu QY, Jin Y, Mao JT, Zhang ZF, Heber D, Dubinett SM, Rao J. Green tea inhibits cycolooxygenase-2 in non-small cell lung cancer cells through the induction of Annexin-1. Biochemical and Biophysical Research Communications. 427: 725-30. PMID 23036202 DOI: 10.1016/J.Bbrc.2012.09.125  0.533
2012 Srivastava MK, Zhu L, Harris-White M, Kar UK, Kar U, Huang M, Johnson MF, Lee JM, Elashoff D, Strieter R, Dubinett S, Sharma S. Myeloid suppressor cell depletion augments antitumor activity in lung cancer. Plos One. 7: e40677. PMID 22815789 DOI: 10.1371/Journal.Pone.0040677  0.482
2012 Dennis M, Wang G, Luo J, Lin Y, Dohadwala M, Abemayor E, Elashoff DA, Sharma S, Dubinett SM, St John MA. Snail controls the mesenchymal phenotype and drives erlotinib resistance in oral epithelial and head and neck squamous cell carcinoma cells. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 147: 726-32. PMID 22568942 DOI: 10.1177/0194599812446407  0.356
2012 Srivastava MK, Andersson Å, Zhu L, Harris-White M, Lee JM, Dubinett S, Sharma S. Myeloid suppressor cells and immune modulation in lung cancer. Immunotherapy. 4: 291-304. PMID 22401635 DOI: 10.2217/Imt.11.178  0.475
2012 Huynh TP, Mah V, Sampson VB, Chia D, Fishbein MC, Horvath S, Alavi M, Wu DC, Harper J, Sarafian T, Dubinett SM, Langhans SA, Goodglick L, Rajasekaran AK. Na,K-ATPase is a target of cigarette smoke and reduced expression predicts poor patient outcome of smokers with lung cancer. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L1150-8. PMID 22345575 DOI: 10.1152/Ajplung.00384.2010  0.377
2012 Heinrich EL, Walser TC, Krysan K, Liclican EL, Grant JL, Rodriguez NL, Dubinett SM. The inflammatory tumor microenvironment, epithelial mesenchymal transition and lung carcinogenesis. Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. 5: 5-18. PMID 21922183 DOI: 10.1007/S12307-011-0089-0  0.81
2012 Stoyanov E, Uddin M, Mankuta D, Dubinett SM, Levi-Schaffer F. Mast cells and histamine enhance the proliferation of non-small cell lung cancer cells. Lung Cancer (Amsterdam, Netherlands). 75: 38-44. PMID 21733595 DOI: 10.1016/J.Lungcan.2011.05.029  0.519
2012 Mendelsohn AH, Lai CK, Shintaku IP, Fishbein MC, Brugman K, Elashoff DA, Abemayor E, Dubinett SM, St John MA. Snail as a novel marker for regional metastasis in head and neck squamous cell carcinoma. American Journal of Otolaryngology. 33: 6-13. PMID 21439681 DOI: 10.1016/J.Amjoto.2010.11.018  0.343
2012 Srivastava MK, Zhu L, Harris-White M, Kar UK, Huang M, Johnson MF, Lee JM, Elashoff D, Strieter R, Dubinett S, Sharma S. Correction: Myeloid Suppressor Cell Depletion Augments Antitumor Activity in Lung Cancer Plos One. 7. DOI: 10.1371/Annotation/5C756E7D-6E97-416F-836A-Dced97Cf46Af  0.431
2012 Ohashi K, Sequist LV, Sos M, Chen X, Rudin CM, Moran T, Arcila ME, Lovly CM, Vnencak-Jones CL, Sasaki H, Dias-Santagata D, Dubinett SM, Riely GJ, Ladanyi M, Franklin WA, et al. Characteristics of NSCLCs harboring NRAS mutations. Journal of Clinical Oncology. 30: 7532-7532. DOI: 10.1200/Jco.2012.30.15_Suppl.7532  0.394
2012 Reckamp KL, Koczywas M, Cristea MC, Dowell J, Gardner B, Milne GL, Figlin RA, Elashoff RM, Dubinett SM. Randomized phase II trial of erlotinib (E) plus high-dose celecoxib (HD-C) or placebo (P) in advanced non-small cell lung cancer. Journal of Clinical Oncology. 30: 7518-7518. DOI: 10.1200/Jco.2012.30.15_Suppl.7518  0.375
2012 Lin Y, Suwarnasarn A, Luo J, Elashoff D, Dubinett S, Wu B, John MS. Abstract 4409: A modular polymer platform for the delivery of cytokines is effective in the treatment of head and neck squamous cell carcinoma (HNSCC) Cancer Research. 72: 4409-4409. DOI: 10.1158/1538-7445.Am2012-4409  0.316
2012 Kachroo P, Lee M, Lee G, Krysan K, Walser TC, Sharma S, Zaknoen S, Dubinett SM, Lee JM. Abstract 339: Apricoxib, a selective COX-2 inhibitor, suppresses IL-27-mediated STAT3 activation and potentiates its inhibition of epithelial to mesenchymal transition in human non-small cell lung cancer Cancer Research. 72: 339-339. DOI: 10.1158/1538-7445.Am2012-339  0.406
2012 Campbell JD, Luo L, Xiao J, Liu G, Aleksyev Y, Elashoff D, Dubinett SM, Lenburg ME, Spira A. Abstract 3154: Sequencing of the small RNA transcriptome in cytologically normal bronchial airway epithelium of smokers with and without lung cancer Cancer Research. 72: 3154-3154. DOI: 10.1158/1538-7445.Am2012-3154  0.502
2012 Lee G, Gardner BK, Hazra S, Kachroo P, Lee M, Krysan K, Walser TC, Larsen JE, Girard L, Wistuba II, Minna JD, Dubinett SM. Abstract 2558: VEGF-dependent suppression of prostaglandin transporter (PGT) expression in Kras mutant human bronchial epithelial cells Cancer Research. 72: 2558-2558. DOI: 10.1158/1538-7445.Am2012-2558  0.308
2012 Grant JL, Walser TC, Minna JD, Shay JW, Dubinett SM. Abstract A15: Snail upregulation of SPARC leads to increased invasion in models of both early-and late-stage NSCLC Clinical Cancer Research. 18: A15-A15. DOI: 10.1158/1078-0432.12Aacriaslc-A15  0.767
2012 Kachroo P, Lee M, Lee G, Krysan K, Sharma S, Dubinett S, Lee J. IL-27 Mediated Inhibition of Epithelial to Mesenchymal Transition is Augmented by STAT1 Activator, 2-(1,8-naphthyridin-2-yl)phenol (2-NP) in Human Non-small Cell Lung Cancer Journal of Surgical Research. 172: 243. DOI: 10.1016/J.Jss.2011.11.382  0.479
2011 Garon EB, Dubinett SM, Kabbinavar FF, Reckamp KL, Marquez-Garban DC, Goodglick L, Sharma S, Stabile LP, Siegfried J, Pietras RJ. Randomized, multicenter phase II study of erlotinib (E) or E plus fulvestrant (F) in previously treated advanced non-small cell lung cancer (NSCLC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: TPS216. PMID 28023479 DOI: 10.1200/Jco.2011.29.15_Suppl.Tps216  0.386
2011 Mao JT, Roth MD, Fishbein MC, Aberle DR, Zhang ZF, Rao JY, Tashkin DP, Goodglick L, Holmes EC, Cameron RB, Dubinett SM, Elashoff R, Szabo E, Elashoff D. Lung cancer chemoprevention with celecoxib in former smokers. Cancer Prevention Research (Philadelphia, Pa.). 4: 984-93. PMID 21733822 DOI: 10.1158/1940-6207.Capr-11-0078  0.452
2011 Sharma S, Srivastava MK, Harris-White M, Lee JM, Dubinett S. MUC1 peptide vaccine mediated antitumor activity in non-small cell lung cancer. Expert Opinion On Biological Therapy. 11: 987-90. PMID 21711210 DOI: 10.1517/14712598.2011.598146  0.499
2011 Lee G, Gardner BK, Elashoff DA, Purcell CM, Sandha HS, Mao JT, Krysan K, Lee JM, Dubinett SM. Elevated levels of CXC chemokine connective tissue activating peptide (CTAP)-III in lung cancer patients. American Journal of Translational Research. 3: 226-33. PMID 21654877  0.349
2011 Andersson A, Srivastava MK, Harris-White M, Huang M, Zhu L, Elashoff D, Strieter RM, Dubinett SM, Sharma S. Role of CXCR3 ligands in IL-7/IL-7R alpha-Fc-mediated antitumor activity in lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3660-72. PMID 21636553 DOI: 10.1158/1078-0432.Ccr-10-3346  0.416
2011 Kar UK, Srivastava MK, Andersson A, Baratelli F, Huang M, Kickhoefer VA, Dubinett SM, Rome LH, Sharma S. Novel CCL21-vault nanocapsule intratumoral delivery inhibits lung cancer growth. Plos One. 6: e18758. PMID 21559281 DOI: 10.1371/Journal.Pone.0018758  0.478
2011 Gomperts BN, Spira A, Massion PP, Walser TC, Wistuba II, Minna JD, Dubinett SM. Evolving concepts in lung carcinogenesis. Seminars in Respiratory and Critical Care Medicine. 32: 32-43. PMID 21500122 DOI: 10.1055/S-0031-1272867  0.512
2011 Mortazavi F, Dubinett S, Rettig M. c-Crk proto-oncogene contributes to transcriptional repression of p120-catenin in non-small cell lung cancer cells. Clinical & Experimental Metastasis. 28: 391-404. PMID 21336985 DOI: 10.1007/S10585-011-9378-8  0.415
2011 Dubinett S, Sharma S. Towards effective immunotherapy for lung cancer: simultaneous targeting of tumor-initiating cells and immune pathways in the tumor microenvironment. Immunotherapy. 1: 721-5. PMID 20636013 DOI: 10.2217/Imt.09.56  0.487
2011 Dennis MS, Wang G, Luo J, Dubinett S, Sidell DR, Abemayor E, St. John M. Snail Drives Erlotinib Resistance in Head and Neck Squamous Cell Carcinoma Cells Otolaryngology–Head and Neck Surgery. 145: P75-P75. DOI: 10.1177/0194599811416318A109  0.374
2011 Srivastava MK, Sharma S, Zhu L, Huang M, Andersson Å, Harris-White M, Kar UK, Hong L, Fishbein M, Dubinett S. Abstract A17: Tumor Snail knockdown reduces tumor burden and metastases by inducing antitumor immune responses in lung cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-A17  0.496
2011 Kachroo P, Zhang L, Walser TC, Cui X, Hazra S, Lin QY, Minna JD, Dubinett SM, Lee JM. Abstract 4268: Interleukin-27 inhibits angiogenesis in non-small cell lung cancer Cancer Research. 71: 4268-4268. DOI: 10.1158/1538-7445.Am2011-4268  0.449
2011 Lee JM, Zhang L, Kachroo P, Cui X, Hazra S, Walser TC, Minna JD, Sharma S, Dubinett SM. Abstract 3425: Interleukin-27 inhibits epithelial mesenchymal transition in lung carcinogenesis Cancer Research. 71: 3425-3425. DOI: 10.1158/1538-7445.Am2011-3425  0.462
2011 Mortazavi F(, Dubinett SM, Rettig MB. Abstract 1084: c-Crk proto-oncogene and TGF-β signaling pathway contribute to transcriptional repression ofp120-cateninin non-small cell lung cancer cells Cancer Research. 71: 1084-1084. DOI: 10.1158/1538-7445.Am2011-1084  0.423
2010 Garon EB, Dubinett SM. Poly(ADP-ribose) polymerase inhibitors. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 5: S455-6. PMID 21102236 DOI: 10.1097/01.Jto.0000391363.10517.56  0.354
2010 Patz EF, Caporaso NE, Dubinett SM, Massion PP, Hirsch FR, Minna JD, Gatsonis C, Duan F, Adams A, Apgar C, Medina RM, Aberle DR. National Lung Cancer Screening Trial American College of Radiology Imaging Network Specimen Biorepository originating from the Contemporary Screening for the Detection of Lung Cancer Trial (NLST, ACRIN 6654): design, intent, and availability of specimens for validation of lung cancer biomarkers. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 5: 1502-6. PMID 20871260 DOI: 10.1097/Jto.0B013E3181F1C634  0.471
2010 Ooi AT, Mah V, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh EL, Chia D, Gower AC, Lenburg ME, Spira A, Solis LM, Wistuba II, ... ... Dubinett SM, et al. Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer. Cancer Research. 70: 6639-48. PMID 20710044 DOI: 10.1158/0008-5472.Can-10-0455  0.496
2010 Dubinett SM, Lee JM, Sharma S, Mulé JJ. Chemokines: can effector cells be redirected to the site of the tumor? Cancer Journal (Sudbury, Mass.). 16: 325-35. PMID 20693843 DOI: 10.1097/Ppo.0B013E3181Eb33Bc  0.403
2010 Mortazavi F, An J, Dubinett S, Rettig M. p120-catenin is transcriptionally downregulated by FOXC2 in non-small cell lung cancer cells. Molecular Cancer Research : McR. 8: 762-74. PMID 20460685 DOI: 10.1158/1541-7786.Mcr-10-0004  0.481
2010 Dohadwala M, Wang G, Heinrich E, Luo J, Lau O, Shih H, Munaim Q, Lee G, Hong L, Lai C, Abemayor E, Fishbein MC, Elashoff DA, Dubinett SM, St John MA. The role of ZEB1 in the inflammation-induced promotion of EMT in HNSCC. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 142: 753-9. PMID 20416468 DOI: 10.1016/J.Otohns.2010.01.034  0.747
2010 Demaria S, Pikarsky E, Karin M, Coussens LM, Chen YC, El-Omar EM, Trinchieri G, Dubinett SM, Mao JT, Szabo E, Krieg A, Weiner GJ, Fox BA, Coukos G, Wang E, et al. Cancer and inflammation: promise for biologic therapy. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 335-51. PMID 20386472 DOI: 10.1097/Cji.0B013E3181D32E74  0.401
2010 Gomperts BN, Spira A, Elashoff DE, Dubinett SM. Lung cancer biomarkers: FISHing in the sputum for risk assessment and early detection. Cancer Prevention Research (Philadelphia, Pa.). 3: 420-3. PMID 20332300 DOI: 10.1158/1940-6207.Capr-10-0052  0.401
2010 Reckamp KL, Koczywas M, Cristea MC, Dowell J, Gardner B, Milne G, Fouladi Rad S, Figlin RA, Elashoff R, Dubinett SM. Randomized, placebo-controlled, phase II trial of EGFR and COX-2 inhibition in advanced non-small cell lung cancer. Journal of Clinical Oncology. 28: TPS337-TPS337. DOI: 10.1200/Jco.2010.28.15_Suppl.Tps337  0.449
2010 Garon EB, Dubinett SM, Hosmer W, Reckamp KL, Kabbinavar FF, Goodglick L, Marquez-Garban DC, Stabile LP, Siegfried J, Pietras RJ. Randomized phase II study of erlotinib (E) alone or combined with fulvestrant (F) in previously treated patients with advanced non-small cell lung cancer (NSCLC). Journal of Clinical Oncology. 28: TPS295-TPS295. DOI: 10.1200/Jco.2010.28.15_Suppl.Tps295  0.376
2010 Lee JM, Garon EB, Baratelli F, Schaue D, Pak PS, Wallace WD, Suh R, Abtin F, Zeng G, Dubinett SM. Phase I trial of CCL21 gene modified dendritic cells in non-small cell lung cancer. Journal of Clinical Oncology. 28: TPS157-TPS157. DOI: 10.1200/Jco.2010.28.15_Suppl.Tps157  0.436
2010 Walser TC, Krysan K, Gardner BK, Hong L, Fishbein MC, Goodglick L, Ooi A, Gomperts BN, Larsen JE, Minna JD, Dubinett SM. Abstract CN12-03: The inflammation-EMT-cancer initiating cell axis in the pathogenesis of lung cancer: Breaking ground in the pursuit of targeted chemoprevention Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-Cn12-03  0.552
2010 Hazra S, Lee G, Grant J, Walser T, Prasad S, Larsen JE, Minna J, Dubinett SM. Abstract B57: Modulation of prostaglandin E2 by statins in human bronchial epithelial cells harboring K-ras mutation: The potential advantage of combination therapy Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-B57  0.717
2010 Hazra S, Gardner BK, Krysan K, Walser TC, Larsen JE, Pertsemlidis A, Shay JW, Minna JD, Spira A, Dubinett SM. Abstract A31: The role of microRNA 125a‐3P in the pathogenesis of lung cancer Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-A31  0.491
2010 Grant JL, Walser TC, Yanagawa J, Lee G, Minna JD, Prasad S, Hazra S, Dubinett SM. Abstract 5592: Lovastatin and low dose celecoxib decrease proliferation and inflammation in a cellular model of lung pre-malignancy Cancer Research. 70: 5592-5592. DOI: 10.1158/1538-7445.Am10-5592  0.756
2010 John MS, Wang G, Luo J, Munaim Q, Lee JM, Burrows F, Zaknoen S, Dubinett SM. Abstract 4459: Apricoxib upregulates 15-PGDH and PGT in HNSCC Cancer Research. 70: 4459-4459. DOI: 10.1158/1538-7445.Am10-4459  0.477
2010 Ooi AT, Mah VH, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh E, Chia D, Gower AC, Lenburg ME, Spira A, Walser T, Wallace WD, ... Dubinett SM, et al. Abstract 4299: Poor prognosis in smokers with non-small cell lung cancer correlates with the presence of a reparative progenitor cell population Cancer Research. 70: 4299-4299. DOI: 10.1158/1538-7445.Am10-4299  0.463
2010 Heinrich EL, Dohadwala M, Charuworn B, Walser TC, Dubinett S. Abstract 2311: IL-1β induction of EMT and impact on drug sensitivity in NSCLC Cancer Research. 70: 2311-2311. DOI: 10.1158/1538-7445.Am10-2311  0.799
2010 Lee KH, Lee S, Yim J, Yoo C, Lee C, Kim YW, Han SK, Shim Y, Sharma S, Dubinett SM, Yang S. Abstract 1474: Polo-like kinase-1 regulation by cyclooxygenase-2 in non small cell lung cancer Cancer Research. 70: 1474-1474. DOI: 10.1158/1538-7445.Am10-1474  0.563
2009 Yanagawa J, Walser TC, Zhu LX, Hong L, Fishbein MC, Mah V, Chia D, Goodglick L, Elashoff DA, Luo J, Magyar CE, Dohadwala M, Lee JM, St John MA, Strieter RM, ... ... Dubinett SM, et al. Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6820-9. PMID 19887480 DOI: 10.1158/1078-0432.Ccr-09-1558  0.54
2009 St John MA, Dohadwala M, Luo J, Wang G, Lee G, Shih H, Heinrich E, Krysan K, Walser T, Hazra S, Zhu L, Lai C, Abemayor E, Fishbein M, Elashoff DA, ... ... Dubinett SM, et al. Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6018-27. PMID 19789323 DOI: 10.1158/1078-0432.Ccr-09-0011  0.741
2009 Reckamp KL, Figlin RA, Burdick MD, Dubinett SM, Elashoff RM, Strieter RM. CXCR4 expression on circulating pan-cytokeratin positive cells is associated with survival in patients with advanced non-small cell lung cancer. Bmc Cancer. 9: 213. PMID 19563666 DOI: 10.1186/1471-2407-9-213  0.529
2009 Andersson A, Yang SC, Huang M, Zhu L, Kar UK, Batra RK, Elashoff D, Strieter RM, Dubinett SM, Sharma S. IL-7 promotes CXCR3 ligand-dependent T cell antitumor reactivity in lung cancer. Journal of Immunology (Baltimore, Md. : 1950). 182: 6951-8. PMID 19454692 DOI: 10.4049/Jimmunol.0803340  0.413
2009 Lee G, Walser TC, Dubinett SM. Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer. Current Opinion in Pulmonary Medicine. 15: 303-7. PMID 19417670 DOI: 10.1097/Mcp.0B013E32832C975A  0.469
2009 Punturieri A, Szabo E, Croxton TL, Shapiro SD, Dubinett SM. Lung cancer and chronic obstructive pulmonary disease: needs and opportunities for integrated research. Journal of the National Cancer Institute. 101: 554-9. PMID 19351920 DOI: 10.1093/Jnci/Djp023  0.427
2009 Lu QY, Yang Y, Jin YS, Zhang ZF, Heber D, Li FP, Dubinett SM, Sondej MA, Loo JA, Rao JY. Effects of green tea extract on lung cancer A549 cells: proteomic identification of proteins associated with cell migration. Proteomics. 9: 757-67. PMID 19137550 DOI: 10.1002/Pmic.200800019  0.41
2009 St. John M, Dohadwala M, Wang G, Luo J, Dubinett S. Proinflammatory Mediators Promote Metastasis in HNSCC Otolaryngology–Head and Neck Surgery. 141: P56-P57. DOI: 10.1016/J.Otohns.2009.06.169  0.326
2009 Lau OD, Sharma S, Wu B, Dubinett SM, St. MA. A Novel Modular Polymer Platform for the Treatment of Head and Neck Squamous Cell Carcinoma The Laryngoscope. 119: S156-S156. DOI: 10.1002/Lary.20417  0.373
2008 Dubinett SM, Mao JT, Hazra S. Focusing downstream in lung cancer prevention: 15-hydroxyprostaglandin dehydrogenase. Cancer Prevention Research (Philadelphia, Pa.). 1: 223-5. PMID 19138963 DOI: 10.1158/1940-6207.Capr-08-0148  0.478
2008 Walser T, Cui X, Yanagawa J, Lee JM, Heinrich E, Lee G, Sharma S, Dubinett SM. Smoking and lung cancer: the role of inflammation. Proceedings of the American Thoracic Society. 5: 811-5. PMID 19017734 DOI: 10.1513/pats.200809-100TH  0.797
2008 Dubinett SM, Aberle DR, Tashkin DP, Mao JT. The partners--airflow obstruction, emphysema, and lung cancer. American Journal of Respiratory and Critical Care Medicine. 178: 665-6. PMID 18796652 DOI: 10.1164/Rccm.200806-902Ed  0.484
2008 Hazra S, Peebles KA, Sharma S, Mao JT, Dubinett SM. The Role of PPARgamma in the Cyclooxygenase Pathway in Lung Cancer. Ppar Research. 2008: 790568. PMID 18769553 DOI: 10.1155/2008/790568  0.54
2008 Baratelli F, Takedatsu H, Hazra S, Peebles K, Luo J, Kurimoto PS, Zeng G, Batra RK, Sharma S, Dubinett SM, Lee JM. Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in non-small cell lung cancer. Journal of Translational Medicine. 6: 38. PMID 18644162 DOI: 10.1186/1479-5876-6-38  0.483
2008 Einhorn LH, Bonomi P, Bunn PA, Camidge DR, Carbone DP, Choy H, Dubinett SM, Gandara DR, Gaspar LE, Govindan R, Johnson DH, Minna JD, Scagliotti G, West HJ, Herbst RS. Summary report 7th Annual Targeted Therapies of the Treatment of Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 3: 545-55. PMID 18449013 DOI: 10.1097/Jto.0B013E318170627F  0.438
2008 Lee JM, Yanagawa J, Peebles KA, Sharma S, Mao JT, Dubinett SM. Inflammation in lung carcinogenesis: new targets for lung cancer chemoprevention and treatment. Critical Reviews in Oncology/Hematology. 66: 208-17. PMID 18304833 DOI: 10.1016/J.Critrevonc.2008.01.004  0.547
2008 Reckamp KL, Gardner BK, Figlin RA, Elashoff D, Krysan K, Dohadwala M, Mao J, Sharma S, Inge L, Rajasekaran A, Dubinett SM. Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline in serum-soluble E-cadherin. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 3: 117-24. PMID 18303430 DOI: 10.1097/Jto.0B013E3181622Bef  0.466
2008 Krysan K, Lee JM, Dohadwala M, Gardner BK, Reckamp KL, Garon E, St John M, Sharma S, Dubinett SM. Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 3: 107-10. PMID 18303428 DOI: 10.1097/Jto.0B013E3181630Ece  0.385
2008 Su H, Seimbille Y, Ferl GZ, Bodenstein C, Fueger B, Kim KJ, Hsu YT, Dubinett SM, Phelps ME, Czernin J, Weber WA. Evaluation of [(18)F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors. European Journal of Nuclear Medicine and Molecular Imaging. 35: 1089-99. PMID 18239919 DOI: 10.1007/S00259-007-0636-6  0.395
2008 Garon EB, Sadeghi S, Kabbinavar FF, Reckamp KL, Marquez-Garban DC, Stabile LP, Goodglick L, Dubinett SM, Siegfried JM, Pietras RJ. Interim safety analysis of a phase II study of erlotinib (E) alone or combined with fulvestrant (F) in previously treated patients with advanced non-small cell lung cancer (NSCLC) Journal of Clinical Oncology. 26: 19091-19091. DOI: 10.1200/Jco.2008.26.15_Suppl.19091  0.407
2008 Walser T, Yanagawa J, Luo J, Liu M, Goodglick L, Hong L, Fishbein M, Shay J, Minna J, Dubinett S. Abstract PR-11: Snail-induced and EMT-mediated early lung cancer development: Promotion of invasion and expansion of stem cell populations Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-Pr-11  0.461
2008 Heinrich E, Charuworn B, Dohadwala M, Dubinett S. Abstract A26: IL-1β dependent epithelial-mesenchymal transition in non-small cell lung cancer Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-A26  0.812
2008 Yanagawa J, Walser TC, Lee JM, Dohadwala M, Zhu LX, Krysan K, Luo J, Sharma S, Dubinett SM. Transcriptional repressor Snail promotes tumor growth and angiogenesis in human non-small cell lung cancer Journal of the American College of Surgeons. 207: S47. DOI: 10.1016/J.Jamcollsurg.2008.06.096  0.509
2008 Andersson A, Buttan A, Batra R, Zhu L, Dubinett S, Sharmax S. OR.88. IL-7/IL-7R alpha-Fc Immune Therapy for Non Small Cell Lung Cancer Clinical Immunology. 127: S36. DOI: 10.1016/J.Clim.2008.03.095  0.411
2007 Peebles KA, Lee JM, Mao JT, Hazra S, Reckamp KL, Krysan K, Dohadwala M, Heinrich EL, Walser TC, Cui X, Baratelli FE, Garon E, Sharma S, Dubinett SM. Inflammation and lung carcinogenesis: applying findings in prevention and treatment. Expert Review of Anticancer Therapy. 7: 1405-21. PMID 17944566 DOI: 10.1586/14737140.7.10.1405  0.825
2007 Hazra S, Dubinett SM. Ciglitazone mediates COX-2 dependent suppression of PGE2 in human non-small cell lung cancer cells. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 77: 51-8. PMID 17697767 DOI: 10.1016/J.Plefa.2007.05.006  0.486
2007 Liu M, Yang SC, Sharma S, Luo J, Cui X, Peebles KA, Huang M, Sato M, Ramirez RD, Shay JW, Minna JD, Dubinett SM. EGFR signaling is required for TGF-β1-mediated COX-2 induction in human bronchial epithelial cells American Journal of Respiratory Cell and Molecular Biology. 37: 578-588. PMID 17600311 DOI: 10.1165/Rcmb.2007-0100Oc  0.428
2007 Hazra S, Batra RK, Tai HH, Sharma S, Cui X, Dubinett SM. Pioglitazone and rosiglitazone decrease prostaglandin E2 in non-small-cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase. Molecular Pharmacology. 71: 1715-20. PMID 17412838 DOI: 10.1124/Mol.106.033357  0.515
2007 Lee JM, Mao JT, Krysan K, Dubinett SM. Significance of cyclooxygenase-2 in prognosis, targeted therapy and chemoprevention of NSCLC. Future Oncology (London, England). 3: 149-53. PMID 17381414 DOI: 10.2217/14796694.3.2.149  0.507
2007 Lu QY, Jin YS, Zhang ZF, Le AD, Heber D, Li FP, Dubinett SM, Rao JY. Green tea induces annexin-I expression in human lung adenocarcinoma A549 cells: involvement of annexin-I in actin remodeling. Laboratory Investigation; a Journal of Technical Methods and Pathology. 87: 456-65. PMID 17351649 DOI: 10.1038/Labinvest.3700534  0.431
2007 Cui X, Zhang L, Luo J, Rajasekaran A, Hazra S, Cacalano N, Dubinett SM. Unphosphorylated STAT6 contributes to constitutive cyclooxygenase-2 expression in human non-small cell lung cancer. Oncogene. 26: 4253-60. PMID 17237818 DOI: 10.1038/Sj.Onc.1210222  0.451
2007 Yang SC, Kim YW, Yoo C, Lee SM, Lee C, Han SK, Shim Y, Lim J, Hillinger S, Zhu L, Dubinett SM, Sharma S. IL-7 ENHANCES THE ANTI-TUMOR RESPONSE IN NON-SMALL CELL LUNG CANCER Chest. 132: 458B. DOI: 10.1378/CHEST.132.4_MEETINGABSTRACTS.458B  0.424
2007 Reckamp KL, Gardner BK, Figlin RA, Elashoff D, Krysan K, Dohadwala M, Inge L, Rajasekaran A, Dubinett SM. Decline in serum soluble E-cadherin and low baseline matrix metalloproteinase-9 are associated with response to combination celecoxib and erlotinib therapy in advanced non-small cell lung cancer Journal of Clinical Oncology. 25: 7640-7640. DOI: 10.1200/Jco.2007.25.18_Suppl.7640  0.413
2007 Reckamp KL, Gardner BK, Elashoff D, Figlin RA, Krysan K, Dohadwala M, Inge L, Rajasekaran A, Dubinett SM. P3-033: Serum biomarkers predict response to combination celecoxib and erlotinib therapy in advanced non-small cell lung cancer Journal of Thoracic Oncology. 2: S621. DOI: 10.1097/01.Jto.0000283790.42985.55  0.451
2007 Arni S, Cardell M, Yang S, Korom S, Opitz I, Lardinois D, Sharma S, Dubinett SM, Weder W, Hillinger S. P3-020: Combined CCL19/IL-7 treatment eradicates tumors in murine models of lung cancer Journal of Thoracic Oncology. 2: S615. DOI: 10.1097/01.Jto.0000283777.95457.Fd  0.476
2007 Dubinett SM. M10-02: Inflammation in lung carcinogenesis: the complicity of host cellular networks in lung tumorigenesis Journal of Thoracic Oncology. 2: S179-S180. DOI: 10.1097/01.Jto.0000282958.22684.74  0.411
2006 Su H, Bodenstein C, Dumont RA, Seimbille Y, Dubinett S, Phelps ME, Herschman H, Czernin J, Weber W. Monitoring tumor glucose utilization by positron emission tomography for the prediction of treatment response to epidermal growth factor receptor kinase inhibitors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5659-67. PMID 17020967 DOI: 10.1158/1078-0432.Ccr-06-0368  0.381
2006 Zeng G, Aldridge ME, Tian X, Seiler D, Zhang X, Jin Y, Rao J, Li W, Chen D, Langford MP, Duggan C, Belldegrun AS, Dubinett SM. Dendritic cell surface calreticulin is a receptor for NY-ESO-1: direct interactions between tumor-associated antigen and the innate immune system. Journal of Immunology (Baltimore, Md. : 1950). 177: 3582-9. PMID 16951317 DOI: 10.4049/Jimmunol.177.6.3582  0.322
2006 Reckamp KL, Krysan K, Morrow JD, Milne GL, Newman RA, Tucker C, Elashoff RM, Dubinett SM, Figlin RA. A phase I trial to determine the optimal biological dose of celecoxib when combined with erlotinib in advanced non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3381-8. PMID 16740761 DOI: 10.1158/1078-0432.Ccr-06-0112  0.412
2006 Krysan K, Reckamp KL, Sharma S, Dubinett SM. The potential and rationale for COX-2 inhibitors in lung cancer. Anti-Cancer Agents in Medicinal Chemistry. 6: 209-20. PMID 16712449 DOI: 10.2174/187152006776930882  0.523
2006 Dohadwala M, Yang SC, Luo J, Sharma S, Batra RK, Huang M, Lin Y, Goodglick L, Krysan K, Fishbein MC, Hong L, Lai C, Cameron RB, Gemmill RM, Drabkin HA, ... Dubinett SM, et al. Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Research. 66: 5338-45. PMID 16707460 DOI: 10.1158/0008-5472.Can-05-3635  0.471
2006 Hillinger S, Yang SC, Batra RK, Strieter RM, Weder W, Dubinett SM, Sharma S. CCL19 reduces tumour burden in a model of advanced lung cancer. British Journal of Cancer. 94: 1029-34. PMID 16598185 DOI: 10.1038/sj.bjc.6603061  0.34
2006 Cui X, Yang SC, Sharma S, Heuze-Vourc'h N, Dubinett SM. IL-4 regulates COX-2 and PGE2 production in human non-small cell lung cancer. Biochemical and Biophysical Research Communications. 343: 995-1001. PMID 16574063 DOI: 10.1016/J.Bbrc.2006.03.073  0.361
2006 Yang SC, Batra RK, Hillinger S, Reckamp KL, Strieter RM, Dubinett SM, Sharma S. Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma. Cancer Research. 66: 3205-13. PMID 16540672 DOI: 10.1158/0008-5472.Can-05-3619  0.451
2006 Hoang B, Zhu L, Shi Y, Frost P, Yan H, Sharma S, Sharma S, Goodglick L, Dubinett S, Lichtenstein A. Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance. Blood. 107: 4484-90. PMID 16497971 DOI: 10.1182/Blood-2005-09-3926  0.323
2006 Pan J, Burdick MD, Belperio JA, Xue YY, Gerard C, Sharma S, Dubinett SM, Strieter RM. CXCR3/CXCR3 ligand biological axis impairs RENCA tumor growth by a mechanism of immunoangiostasis. Journal of Immunology (Baltimore, Md. : 1950). 176: 1456-64. PMID 16424173 DOI: 10.4049/Jimmunol.176.3.1456  0.365
2006 Mao JT, Fishbein MC, Adams B, Roth MD, Goodglick L, Hong L, Burdick M, Strieter ER, Holmes C, Tashkin DP, Dubinett SM. Celecoxib decreases Ki-67 proliferative index in active smokers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 314-20. PMID 16397057 DOI: 10.1158/1078-0432.Ccr-05-1440  0.429
2006 Liu W, Dubinett S, Patterson SL, Kelly KA. COX-2 inhibition affects growth rate of Chlamydia muridarum within epithelial cells. Microbes and Infection / Institut Pasteur. 8: 478-86. PMID 16297651 DOI: 10.1016/J.Micinf.2005.07.026  0.351
2006 Zhang L, Sharma S, Hershman JM, Brent GA, Dubinett SM, Huang M. Iodide sensitizes genetically modified non-small cell lung cancer cells to ionizing radiation. Cancer Gene Therapy. 13: 74-81. PMID 16052231 DOI: 10.1038/Sj.Cgt.7700875  0.466
2006 Reckamp KL, Czernin J, Weber WA, Dubinett SM, Figlin RA. Targeted COX-2 and EGFR TK inhibition in advanced non-small cell lung cancer Journal of Clinical Oncology. 24: 7179-7179. DOI: 10.1200/Jco.2006.24.18_Suppl.7179  0.407
2005 Weinberg OK, Marquez-Garban DC, Fishbein MC, Goodglick L, Garban HJ, Dubinett SM, Pietras RJ. Aromatase inhibitors in human lung cancer therapy. Cancer Research. 65: 11287-91. PMID 16357134 DOI: 10.1158/0008-5472.Can-05-2737  0.52
2005 Dalwadi H, Krysan K, Heuze-Vourc'h N, Dohadwala M, Elashoff D, Sharma S, Cacalano N, Lichtenstein A, Dubinett S. Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 7674-82. PMID 16278387 DOI: 10.1158/1078-0432.Ccr-05-1205  0.5
2005 Rodriguez PC, Hernandez CP, Quiceno D, Dubinett SM, Zabaleta J, Ochoa JB, Gilbert J, Ochoa AC. Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma. The Journal of Experimental Medicine. 202: 931-9. PMID 16186186 DOI: 10.1084/Jem.20050715  0.525
2005 Mao JT, Cui X, Reckamp K, Liu M, Krysan K, Dalwadi H, Sharma S, Hazra S, Strieter R, Gardner B, Dubinett SM. Chemoprevention strategies with cyclooxygenase-2 inhibitors for lung cancer. Clinical Lung Cancer. 7: 30-9. PMID 16098242 DOI: 10.3816/Clc.2005.N.019  0.528
2005 Krysan K, Reckamp KL, Dalwadi H, Sharma S, Rozengurt E, Dohadwala M, Dubinett SM. Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner. Cancer Research. 65: 6275-81. PMID 16024629 DOI: 10.1158/0008-5472.Can-05-0216  0.462
2005 Sharma S, Zhu L, Yang SC, Zhang L, Lin J, Hillinger S, Gardner B, Reckamp K, Strieter RM, Huang M, Batra RK, Dubinett SM. Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses. Journal of Immunology (Baltimore, Md. : 1950). 175: 813-9. PMID 16002678 DOI: 10.4049/Jimmunol.175.2.813  0.39
2005 Sharma S, Yang SC, Zhu L, Reckamp K, Gardner B, Baratelli F, Huang M, Batra RK, Dubinett SM. Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer. Cancer Research. 65: 5211-20. PMID 15958566 DOI: 10.1158/0008-5472.Can-05-0141  0.455
2005 Heuzé-Vourc'h N, Liu M, Dalwadi H, Baratelli FE, Zhu L, Goodglick L, Põld M, Sharma S, Ramirez RD, Shay JW, Minna JD, Strieter RM, Dubinett SM. IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression Biochemical and Biophysical Research Communications. 333: 470-475. PMID 15950941 DOI: 10.1016/J.Bbrc.2005.05.122  0.367
2005 Baratelli F, Krysan K, Heuzé-Vourc'h N, Zhu L, Escuadro B, Sharma S, Reckamp K, Dohadwala M, Dubinett SM. PGE2 confers survivin-dependent apoptosis resistance in human monocyte-derived dendritic cells. Journal of Leukocyte Biology. 78: 555-64. PMID 15908458 DOI: 10.1189/Jlb.1004569  0.328
2005 Zeng G, Aldridge ME, Wang Y, Pantuck AJ, Wang AY, Liu YX, Han Y, Yuan YH, Robbins PF, Dubinett SM, deKernion JB, Belldegrun AS. Dominant B cell epitope from NY-ESO-1 recognized by sera from a wide spectrum of cancer patients: implications as a potential biomarker. International Journal of Cancer. Journal International Du Cancer. 114: 268-73. PMID 15540228 DOI: 10.1002/Ijc.20716  0.4
2005 Reckamp KL, Dubinett SM, Krysan K, Figlin RA. A phase I trial of targeted COX-2 and EGFR TK inhibition in advanced NSCLC Journal of Clinical Oncology. 23: 7112-7112. DOI: 10.1200/Jco.2005.23.16_Suppl.7112  0.313
2005 Hillinger S, Yang S, Cardell M, Korom S, Lardinois D, Dubinett S, Sharma S, Weder W. P-050 Loco-regional chemokine treatment inhibits tumor growth in anorthotopic model of lung cancer Lung Cancer. 49: S127. DOI: 10.1016/S0169-5002(05)80544-6  0.463
2005 Hillinger S, Yang S, Huang M, Batra R, Strieter R, Weder W, Dubinett S, Sharma S. P-049 Systemic chemokine CCL19 administration reduces tumorburden in a late stage model of spontaneous lung cancer Lung Cancer. 49: S127. DOI: 10.1016/S0169-5002(05)80543-4  0.426
2005 Dalwadi H, Krysan K, Heuze-Vourc'h N, Dohadwala M, Elashoff D, Sharma S, Cacalano N, Lichtenstein A, Dubinett S. P-026 IL-6 induces apoptosis resistance and VEGF production throughmultiple signaling pathways in non-small cell lung cancer Lung Cancer. 49: S122. DOI: 10.1016/S0169-5002(05)80520-3  0.455
2005 Reckamp K, Krysan K, Dubinett S, Figlin R. O-194 Targeted COX-2 and EGFR inhibition in advanced NSCLC Lung Cancer. 49: S65. DOI: 10.1016/S0169-5002(05)80329-0  0.305
2004 Strieter RM, Belperio JA, Burdick MD, Sharma S, Dubinett SM, Keane MP. CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer. Annals of the New York Academy of Sciences. 1028: 351-60. PMID 15650260 DOI: 10.1196/Annals.1322.041  0.535
2004 Mao JT, Tsu IH, Dubinett SM, Adams B, Sarafian T, Baratelli F, Roth MD, Serio KJ. Modulation of pulmonary leukotriene B4 production by cyclooxygenase-2 inhibitors and lipopolysaccharide. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 6872-8. PMID 15501964 DOI: 10.1158/1078-0432.Ccr-04-0945  0.438
2004 Baratelli FE, Heuzé-Vourc'h N, Krysan K, Dohadwala M, Riedl K, Sharma S, Dubinett SM. Prostaglandin E2-dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix Journal of Immunology. 173: 5458-5466. PMID 15494493 DOI: 10.4049/Jimmunol.173.9.5458  0.343
2004 Põld M, Krysan K, Põld A, Dohadwala M, Heuze-Vourc'h N, Mao JT, Riedl KL, Sharma S, Dubinett SM. Cyclooxygenase-2 modulates the insulin-like growth factor axis in non-small-cell lung cancer Cancer Research. 64: 6549-6555. PMID 15374967 DOI: 10.1158/0008-5472.Can-04-1225  0.431
2004 Krysan K, Dalwadi H, Sharma S, Põld M, Dubinett S. Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer. Cancer Research. 64: 6359-62. PMID 15374938 DOI: 10.1158/0008-5472.Can-04-1681  0.504
2004 Riedl K, Krysan K, Põld M, Dalwadi H, Heuze-Vourc'h N, Dohadwala M, Liu M, Cui X, Figlin R, Mao JT, Strieter R, Sharma S, Dubinett SM. Multifaceted roles of cyclooxygenase-2 in lung cancer Drug Resistance Updates. 7: 169-184. PMID 15296859 DOI: 10.1016/J.Drup.2004.04.003  0.529
2004 Dubinett SM, Elashoff D, Meyerson M. Assessing prognosis in non-small-cell lung cancer: Avenues to a more complete picture? Journal of Clinical Oncology. 22: 3209-3211. PMID 15249586 DOI: 10.1200/Jco.2004.05.931  0.418
2004 Sandler AB, Dubinett SM. COX-2 inhibition and lung cancer. Seminars in Oncology. 31: 45-52. PMID 15179623 DOI: 10.1053/J.Seminoncol.2004.03.045  0.517
2004 Krysan K, Dohadwala M, Luo J, Lin Y, Zhu L, Heuze-Vourc'h N, Goodglick L, Merchant F, Seligson D, Pold M, Strieter R, Sharma S, Dubinett S. Cyclooxygenase-2-dependent expression of survivin in non-small cell lung cancer. Chest. 125: 140S. PMID 15136466 DOI: 10.1378/Chest.125.5_Suppl.140S  0.529
2004 Yang SC, Hillinger S, Riedl K, Zhang L, Zhu L, Huang M, Atianzar K, Kuo BY, Gardner B, Batra RK, Strieter RM, Dubinett SM, Sharma S. Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2891-901. PMID 15102698 DOI: 10.1158/1078-0432.Ccr-03-0380  0.367
2004 Põld M, Zhu LX, Sharma S, Burdick MD, Lin Y, Lee PP, Põld A, Luo J, Krysan K, Dohadwala M, Mao JT, Batra RK, Strieter RM, Dubinett SM. Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer. Cancer Research. 64: 1853-60. PMID 14996749 DOI: 10.1158/0008-5472.Can-03-3262  0.507
2004 Gardner B, Zhu LX, Roth MD, Tashkin DP, Dubinett SM, Sharma S. Cocaine modulates cytokine and enhances tumor growth through sigma receptors. Journal of Neuroimmunology. 147: 95-8. PMID 14741436 DOI: 10.1016/J.Jneuroim.2003.10.020  0.334
2003 Mao JT, Roth MD, Serio KJ, Baratelli F, Zhu L, Holmes EC, Strieter RM, Dubinett SM. Celecoxib modulates the capacity for prostaglandin E2 and interleukin-10 production in alveolar macrophages from active smokers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 5835-41. PMID 14676104  0.431
2003 Hillinger S, Yang SC, Zhu L, Huang M, Duckett R, Atianzar K, Batra RK, Strieter RM, Dubinett SM, Sharma S. EBV-induced molecule 1 ligand chemokine (ELC/CCL19) promotes IFN-gamma-dependent antitumor responses in a lung cancer model. Journal of Immunology (Baltimore, Md. : 1950). 171: 6457-65. PMID 14662845 DOI: 10.4049/Jimmunol.171.12.6457  0.41
2003 Riedl K, Baratelli F, Batra RK, Yang SC, Luo J, Escuadro B, Figlin R, Strieter R, Sharma S, Dubinett S. Overexpression of CCL-21/secondary lymphoid tissue chemokine in human dendritic cells augments chemotactic activities for lymphocytes and antigen presenting cells. Molecular Cancer. 2: 35. PMID 14613584 DOI: 10.1186/1476-4598-2-35  0.367
2003 Krysan K, Merchant FH, Zhu L, Dohadwala M, Luo J, Lin Y, Heuze-Vourc'h N, Põld M, Seligson D, Chia D, Goodglick L, Wang H, Strieter R, Sharma S, Dubinett S. COX-2-dependent stabilization of survivin in non-small cell lung cancer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 206-8. PMID 14597555 DOI: 10.1096/Fj.03-0369Fje  0.491
2003 Sharma S, Batra RK, Yang SC, Hillinger S, Zhu L, Atianzar K, Strieter RM, Riedl K, Huang M, Dubinett SM. Interleukin-7 gene-modified dendritic cells reduce pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma. Human Gene Therapy. 14: 1511-24. PMID 14577913 DOI: 10.1089/104303403322495025  0.449
2003 Gardner B, Zhu LX, Sharma S, Tashkin DP, Dubinett SM. Methanandamide increases COX-2 expression and tumor growth in murine lung cancer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 2157-9. PMID 12958151 DOI: 10.1096/Fj.03-0254Fje  0.446
2003 Zhang L, Sharma S, Zhu LX, Kogai T, Hershman JM, Brent GA, Dubinett SM, Huang M. Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells. Cancer Research. 63: 5065-72. PMID 12941836  0.411
2003 Dubinett SM, Sharma S, Huang M, Dohadwala M, Pold M, Mao JT. Cyclooxygenase-2 in lung cancer. Progress in Experimental Tumor Research. 37: 138-62. PMID 12795053 DOI: 10.1159/000071371  0.491
2003 Sharma S, Yang SC, Hillinger S, Zhu LX, Huang M, Batra RK, Lin JF, Burdick MD, Strieter RM, Dubinett SM. SLC/CCL21-mediated anti-tumor responses require IFNgamma, MIG/CXCL9 and IP-10/CXCL10. Molecular Cancer. 2: 22. PMID 12740040 DOI: 10.1186/1476-4598-2-22  0.359
2003 Heuze-Vourc'h N, Zhu L, Krysan K, Batra RK, Sharma S, Dubinett SM. Abnormal interleukin 10Ralpha expression contributes to the maintenance of elevated cyclooxygenase-2 in non-small cell lung cancer cells. Cancer Research. 63: 766-70. PMID 12591723  0.38
2003 Sharma S, Huang M, Dohadwala M, Pold M, Batra RK, Dubinett SM. Cyclooxygenase 2-dependent regulation of antitumor immunity in lung cancer. Methods in Molecular Medicine. 75: 723-36. PMID 12407775 DOI: 10.1385/1-59259-324-0:723  0.482
2003 Sharma S, Yang SC, Batra RK, Dubinett SM. Intratumoral therapy with cytokine gene-modified dendritic cells in murine lung cancer models. Methods in Molecular Medicine. 75: 711-22. PMID 12407774 DOI: 10.1385/1-59259-324-0:711  0.481
2003 Dubinett SM, Krysan K, Pold M, Sharma S, Riedl K, Dohadwala M. E-21. Cyclooxygenase-2-dependent regulation of the malignant phenotype in non-small cell lung cancer Lung Cancer. 41: S28. DOI: 10.1016/S0169-5002(03)90428-4  0.524
2002 Tashkin DP, Baldwin GC, Sarafian T, Dubinett S, Roth MD. Respiratory and immunologic consequences of marijuana smoking. Journal of Clinical Pharmacology. 42: 71S-81S. PMID 12412839 DOI: 10.1002/J.1552-4604.2002.Tb06006.X  0.394
2002 Dohadwala M, Batra RK, Luo J, Lin Y, Krysan K, Pold M, Sharma S, Dubinett SM. Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion. The Journal of Biological Chemistry. 277: 50828-33. PMID 12393872 DOI: 10.1074/Jbc.M210707200  0.376
2002 Huang M, Sharma S, Zhu LX, Keane MP, Luo J, Zhang L, Burdick MD, Lin YQ, Dohadwala M, Gardner B, Batra RK, Strieter RM, Dubinett SM. IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis. The Journal of Clinical Investigation. 109: 931-7. PMID 11927620 DOI: 10.1172/Jci14685  0.326
2002 Põld M, Dohadwala M, Luo J, Lin Y, Dubinett S. Microarray identifies cyclo-oxygenase-2-dependent modulation of insulin-like growth factor binding protein-3 in non-small cell lung cancer cells. Chest. 121: 29S-30S. PMID 11893667 DOI: 10.1378/Chest.121.3_Suppl.29S  0.436
2001 Huang M, Batra RK, Kogai T, Lin YQ, Hershman JM, Lichtenstein A, Sharma S, Zhu LX, Brent GA, Dubinett SM. Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer. Cancer Gene Therapy. 8: 612-8. PMID 11571539 DOI: 10.1038/Sj.Cgt.7700354  0.509
2001 Dohadwala M, Luo J, Zhu L, Lin Y, Dougherty GJ, Sharma S, Huang M, Pold M, Batra RK, Dubinett SM. Non-small cell lung cancer cyclooxygenase-2-dependent invasion is mediated by CD44. The Journal of Biological Chemistry. 276: 20809-12. PMID 11320076 DOI: 10.1074/Jbc.C100140200  0.498
2000 Batra RK, Sharma S, Dubinett SM. New gene and cell-based therapies for lung cancer. Seminars in Respiratory and Critical Care Medicine. 21: 463-72. PMID 16088747 DOI: 10.1055/S-2000-9455  0.468
2000 Zhu LX, Sharma S, Stolina M, Gardner B, Roth MD, Tashkin DP, Dubinett SM. Delta-9-tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway. Journal of Immunology (Baltimore, Md. : 1950). 165: 373-80. PMID 10861074 DOI: 10.4049/Jimmunol.165.1.373  0.398
2000 Batra RK, Dubinett SM, Henkle BW, Sharma S, Gardner BK. Adenoviral gene transfer is inhibited by soluble factors in malignant pleural effusions. American Journal of Respiratory Cell and Molecular Biology. 22: 613-9. PMID 10783134 DOI: 10.1165/Ajrcmb.22.5.3970  0.352
2000 Dubinett SM, Batra RK, Miller PW, Sharma S. Tumor antigens in thoracic malignancy. American Journal of Respiratory Cell and Molecular Biology. 22: 524-7. PMID 10783122 DOI: 10.1165/Ajrcmb.22.5.F186  0.323
2000 Sharma S, Stolina M, Luo J, Strieter RM, Burdick M, Zhu LX, Batra RK, Dubinett SM. Secondary lymphoid tissue chemokine mediates T cell-dependent antitumor responses in vivo. Journal of Immunology (Baltimore, Md. : 1950). 164: 4558-63. PMID 10779757 DOI: 10.4049/Jimmunol.164.9.4558  0.355
2000 Miller PW, Sharma S, Stolina M, Butterfield LH, Luo J, Lin Y, Dohadwala M, Batra RK, Wu L, Economou JS, Dubinett SM. Intratumoral administration of adenoviral interleukin 7 gene-modified dendritic cells augments specific antitumor immunity and achieves tumor eradication. Human Gene Therapy. 11: 53-65. PMID 10646639 DOI: 10.1089/10430340050016157  0.357
2000 Kiertscher SM, Luo J, Dubinett SM, Roth MD. Tumors promote altered maturation and early apoptosis of monocyte-derived dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 164: 1269-76. PMID 10640740 DOI: 10.4049/Jimmunol.164.3.1269  0.361
2000 Stolina M, Sharma S, Lin Y, Dohadwala M, Gardner B, Luo J, Zhu L, Kronenberg M, Miller PW, Portanova J, Lee JC, Dubinett SM. Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis. Journal of Immunology (Baltimore, Md. : 1950). 164: 361-70. PMID 10605031 DOI: 10.4049/Jimmunol.164.1.361  0.403
1999 Batra RK, Guttridge DC, Brenner DA, Dubinett SM, Baldwin AS, Boucher RC. IkappaBalpha gene transfer is cytotoxic to squamous-cell lung cancer cells and sensitizes them to tumor necrosis factor-alpha-mediated cell death. American Journal of Respiratory Cell and Molecular Biology. 21: 238-45. PMID 10423407 DOI: 10.1165/Ajrcmb.21.2.3470  0.465
1998 Dubinett SM, Miller PW, Sharma S, Batra RK. Gene therapy for lung cancer. Hematology/Oncology Clinics of North America. 12: 569-94. PMID 9684099 DOI: 10.1016/S0889-8588(05)70009-5  0.462
1997 Sharma S, Miller PW, Stolina M, Zhu L, Huang M, Paul RW, Dubinett SM. Multicomponent gene therapy vaccines for lung cancer: effective eradication of established murine tumors in vivo with interleukin-7/herpes simplex thymidine kinase-transduced autologous tumor and ex vivo activated dendritic cells. Gene Therapy. 4: 1361-70. PMID 9472560 DOI: 10.1038/Sj.Gt.3300531  0.444
1997 Baldwin GC, Tashkin DP, Buckley DM, Park AN, Dubinett SM, Roth MD. Marijuana and cocaine impair alveolar macrophage function and cytokine production. American Journal of Respiratory and Critical Care Medicine. 156: 1606-13. PMID 9372683 DOI: 10.1164/Ajrccm.156.5.9704146  0.334
1997 Hagenbaugh A, Sharma S, Dubinett SM, Wei SH, Aranda R, Cheroutre H, Fowell DJ, Binder S, Tsao B, Locksley RM, Moore KW, Kronenberg M. Altered immune responses in interleukin 10 transgenic mice. The Journal of Experimental Medicine. 185: 2101-10. PMID 9182682 DOI: 10.1084/Jem.185.12.2101  0.325
1996 Wang J, Huang M, Lee P, Komanduri K, Sharma S, Chen G, Dubinett SM. Interleukin-8 inhibits non-small cell lung cancer proliferation: a possible role for regulation of tumor growth by autocrine and paracrine pathways. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 16: 53-60. PMID 8640452 DOI: 10.1089/Jir.1996.16.53  0.442
1995 Dubinett SM, Huang M, Dhanani S, Economou JS, Wang J, Lee P, Sharma S, Dougherty GJ, McBride WH. Down-regulation of murine fibrosarcoma transforming growth factor-beta 1 expression by interleukin 7. Journal of the National Cancer Institute. 87: 593-7. PMID 7752257 DOI: 10.1093/Jnci/87.8.593  0.35
1994 Dhanani S, Huang M, Wang J, Dubinett SM. Interferon-alpha inhibits murine macrophage transforming growth factor-beta mRNA expression. Inflammation. 18: 301-9. PMID 8088926 DOI: 10.1007/Bf01534271  0.309
1994 Kelley DM, Lichtenstein A, Wang J, Taylor AN, Dubinett SM. Corticotropin-releasing factor reduces lipopolysaccharide-induced pulmonary vascular leak. Immunopharmacology and Immunotoxicology. 16: 139-48. PMID 8077603 DOI: 10.3109/08923979409007086  0.311
1993 Dubinett SM, Patrone L, Huang M, Markowitz J, McBride WH, Economou JS, Tobias J, Kelley D, Yan D, Seelig M. Interleukin-2-responsive wound-infiltrating lymphocytes in surgical adjuvant cancer immunotherapy. Immunological Investigations. 22: 13-23. PMID 8440522 DOI: 10.3109/08820139309066190  0.344
1993 Nguyen QH, Moy RL, Roth MD, Yamamoto R, Tomono S, Dubinett SM. Expression of CD45 isoforms in fresh and IL-2-cultured tumor-infiltrating lymphocytes from basal cell carcinoma. Cellular Immunology. 146: 421-30. PMID 8174180 DOI: 10.1006/Cimm.1993.1038  0.348
1993 Dubinett SM, Huang M, Dhanani S, Kelley D, Lichtenstein A, Grody WW, Mintz LE. In Situ Regulation of Pulmonary Macrophage TNF-α mRNA Expression by IL2 Chest. 103: 91S-94S. DOI: 10.1378/Chest.103.2_Supplement.91S  0.315
1987 Kradin RL, Boyle LA, Preffer FI, Callahan RJ, Barlai-Kovach M, Strauss HW, Dubinett S, Kurnick JT. Tumor-derived interleukin-2-dependent lymphocytes in adoptive immunotherapy of lung cancer. Cancer Immunology, Immunotherapy : Cii. 24: 76-85. PMID 3493073 DOI: 10.1007/BF00199837  0.363
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