Philip Lazarus - Publications

Affiliations: 
Pennsylvania State University, State College, PA, United States 
Area:
Molecular Biology, Cell Biology, Pharmacology

87 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Neumiller JJ, Chen G, Newsome C, Hughes S, Lazarus P, White JR. Assessment of Regular and NPH Insulin Concentration via Two Methods of Quantification: The Washington State Insulin Concentration Study (WICS). Journal of Diabetes Science and Technology. 1932296819883291. PMID 31640422 DOI: 10.1177/1932296819883291  0.32
2019 Kozlovich S, Chen G, Watson CJ, Blot WJ, Lazarus P. The role of L- and D-menthol in the glucuronidation and detoxification of the major lung carcinogen, NNAL. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31578206 DOI: 10.1124/dmd.119.088351  0.32
2019 Sutliff AK, Shi J, Watson CJW, Hunt M, Chen G, Zhu HJ, Lazarus P. Potential Regulation of UGT2B10 and UGT2B7 by miR-485-5p in human liver. Molecular Pharmacology. PMID 31554697 DOI: 10.1124/mol.119.115881  0.32
2019 Kozlovich S, Chen G, Watson CJ, Lazarus P. Prominent Stereo-selectivity of NNAL Glucuronidation in Upper Aerodigestive Tract Tissues. Chemical Research in Toxicology. PMID 31307193 DOI: 10.1021/acs.chemrestox.9b00217  0.32
2019 Sutliff AK, Watson CJW, Chen G, Lazarus P. Regulation of UGT2A1 by miR-196a-5p and miR-196b-5p and its implications for lung cancer risk. The Journal of Pharmacology and Experimental Therapeutics. PMID 30850392 DOI: 10.1124/jpet.118.255935  0.32
2018 Perez-Paramo YX, Chen G, Ashmore JH, Watson CJW, Nasrin S, Adams-Haduch J, Wang R, Gao YT, Koh WP, Yuan JM, Lazarus P. Nicotine-N'-oxidation by flavin monooxygenase enzymes. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 30381441 DOI: 10.1158/1055-9965.EPI-18-0669  0.32
2018 Luo S, Chen G, Truica CI, Baird CC, Xia Z, Lazarus P. Identification and Quantification of Novel Major Metabolites of the Steroidal Aromatase Inhibitor, Exemestane. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30257855 DOI: 10.1124/dmd.118.081166  0.32
2018 Denton TT, Srivastava P, Xia Z, Chen G, Watson C, Wynd A, Lazarus P. Identification of the 4-position of 3-alkynyl and 3-heteroaromatic substituted pyridine methanamines as a key modification site eliciting increased potency and enhanced selectivity for cytochrome P-450 2A6 inhibition. Journal of Medicinal Chemistry. PMID 29995408 DOI: 10.1021/acs.jmedchem.8b00084  0.32
2017 Laube BL, Afshar-Mohajer N, Koehler K, Chen G, Lazarus P, Collaco JM, McGrath-Morrow SA. Acute and chronic in vivo effects of exposure to nicotine and propylene glycol from an E-cigarette on mucociliary clearance in a murine model. Inhalation Toxicology. 1-9. PMID 28651446 DOI: 10.1080/08958378.2017.1336585  0.32
2017 Peterson A, Xia Z, Chen G, Lazarus P. In vitro metabolism of exemestane by hepatic cytochrome P450s: impact of nonsynonymous polymorphisms on formation of the active metabolite 17β-dihydroexemestane. Pharmacology Research & Perspectives. 5: e00314. PMID 28603633 DOI: 10.1002/prp2.314  0.32
2017 Peterson A, Xia Z, Chen G, Lazarus P. Exemestane potency is unchanged by common nonsynonymous polymorphisms in CYP19A1: results of a novel anti-aromatase activity assay examining exemestane and its derivatives. Pharmacology Research & Perspectives. 5: e00313. PMID 28603632 DOI: 10.1002/prp2.313  0.32
2016 Dluzen DF, Sutliff A, Chen G, Watson C, Ishmael FT, Lazarus P. Regulation of UGT2B expression and activity by miR-216b in liver cancer cell lines. The Journal of Pharmacology and Experimental Therapeutics. PMID 27474751 DOI: 10.1124/jpet.116.235044  0.32
2016 Chen G, Luo S, Kozlovich S, Lazarus P. Association between glucuronidation genotypes and urinary NNAL metabolic phenotypes in smokers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 27197298 DOI: 10.1158/1055-9965.EPI-15-1245  0.32
2016 Platt A, Xia Z, Liu Y, Chen G, Lazarus P. Impact of nonsynonymous single nucleotide polymorphisms on in-vitro metabolism of exemestane by hepatic cytosolic reductases. Pharmacogenetics and Genomics. PMID 27111237 DOI: 10.1097/FPC.0000000000000226  0.32
2016 White JR, Padowski JM, Zhong Y, Chen G, Luo S, Lazarus P, Layton ME, McPherson S. Pharmacokinetic analysis and comparison of caffeine administered rapidly or slowly in coffee chilled or hot versus chilled energy drink in healthy young adults. Clinical Toxicology (Philadelphia, Pa.). 54: 308-12. PMID 27100333 DOI: 10.3109/15563650.2016.1146740  0.32
2015 Jones NR, Ashmore JH, Lee SY, Richie JP, Lazarus P, Muscat JE. Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks. Cancers. 7: 2386-96. PMID 26690219 DOI: 10.3390/cancers7040898  0.32
2015 Kozlovich S, Chen G, Lazarus P. Stereospecific Metabolism of the Tobacco Specific Nitrosamine, NNAL. Chemical Research in Toxicology. PMID 26452127 DOI: 10.1021/acs.chemrestox.5b00278  0.32
2015 Smith D, Aherrera A, Lopez A, Neptune E, Winickoff JP, Klein JD, Chen G, Lazarus P, Collaco JM, McGrath-Morrow SA. Adult Behavior in Male Mice Exposed to E-Cigarette Nicotine Vapors during Late Prenatal and Early Postnatal Life. Plos One. 10: e0137953. PMID 26372012 DOI: 10.1371/journal.pone.0137953  0.32
2015 Ashmore JH, Gallagher CJ, Lesko SM, Muscat JE, Hartman TJ, Lazarus P. No association between vitamin D intake, VDR polymorphisms, and colorectal cancer in a population-based case-control study. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 26224799 DOI: 10.1158/1055-9965.EPI-15-0284  0.32
2015 Gufford BT, Chen G, Vergara AG, Lazarus P, Oberlies NH, Paine MF. Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product-Drug Interaction. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1353-9. PMID 26070840 DOI: 10.1124/dmd.115.065086  0.32
2015 McGrath-Morrow SA, Hayashi M, Aherrera A, Lopez A, Malinina A, Collaco JM, Neptune E, Klein JD, Winickoff JP, Breysse P, Lazarus P, Chen G. The effects of electronic cigarette emissions on systemic cotinine levels, weight and postnatal lung growth in neonatal mice. Plos One. 10: e0118344. PMID 25706869 DOI: 10.1371/journal.pone.0118344  0.32
2015 Conway DI, Brenner DR, McMahon AD, Macpherson LM, Agudo A, Ahrens W, Bosetti C, Brenner H, Castellsague X, Chen C, Curado MP, Curioni OA, Dal Maso L, Daudt AW, de Gois Filho JF, ... ... Lazarus P, et al. Estimating and explaining the effect of education and income on head and neck cancer risk: INHANCE consortium pooled analysis of 31 case-control studies from 27 countries. International Journal of Cancer. Journal International Du Cancer. 136: 1125-39. PMID 24996155 DOI: 10.1002/ijc.29063  0.32
2015 Modesto JL, Hull A, Angstadt AY, Berg A, Gallagher CJ, Lazarus P, Muscat JE. NNK reduction pathway gene polymorphisms and risk of lung cancer. Molecular Carcinogenesis. 54: E94-E102. PMID 24976539 DOI: 10.1002/mc.22187  0.32
2015 Zhang LR, Morgenstern H, Greenland S, Chang SC, Lazarus P, Teare MD, Woll PJ, Orlow I, Cox B, Brhane Y, Liu G, Hung RJ. Cannabis smoking and lung cancer risk: Pooled analysis in the International Lung Cancer Consortium. International Journal of Cancer. Journal International Du Cancer. 136: 894-903. PMID 24947688 DOI: 10.1002/ijc.29036  0.32
2014 Gufford BT, Chen G, Lazarus P, Graf TN, Oberlies NH, Paine MF. Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 1675-83. PMID 25008344 DOI: 10.1124/dmd.114.059451  0.32
2014 Angstadt AY, Hartman TJ, Lesko SM, Muscat JE, Zhu J, Gallagher CJ, Lazarus P. The effect of UGT1A and UGT2B polymorphisms on colorectal cancer risk: haplotype associations and gene–environment interactions. Genes, Chromosomes & Cancer. 53: 454-66. PMID 24822274 DOI: 10.1002/gcc.22157  0.32
2014 Kim CH, Lee YC, Hung RJ, McNallan SR, Cote ML, Lim WY, Chang SC, Kim JH, Ugolini D, Chen Y, Liloglou T, Andrew AS, Onega T, Duell EJ, Field JK, ... Lazarus P, et al. Exposure to secondhand tobacco smoke and lung cancer by histological type: a pooled analysis of the International Lung Cancer Consortium (ILCCO). International Journal of Cancer. Journal International Du Cancer. 135: 1918-30. PMID 24615328 DOI: 10.1002/ijc.28835  0.32
2014 Jones NR, Lazarus P. UGT2B gene expression analysis in multiple tobacco carcinogen-targeted tissues. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 529-36. PMID 24459179 DOI: 10.1124/dmd.113.054718  0.32
2014 Dluzen DF, Sun D, Salzberg AC, Jones N, Bushey RT, Robertson GP, Lazarus P. Regulation of UDP-glucuronosyltransferase 1A1 expression and activity by microRNA 491-3p. The Journal of Pharmacology and Experimental Therapeutics. 348: 465-77. PMID 24399855 DOI: 10.1124/jpet.113.210658  0.32
2014 Marks MA, Chaturvedi AK, Kelsey K, Straif K, Berthiller J, Schwartz SM, Smith E, Wyss A, Brennan P, Olshan AF, Wei Q, Sturgis EM, Zhang ZF, Morgenstern H, Muscat J, ... Lazarus P, et al. Association of marijuana smoking with oropharyngeal and oral tongue cancers: pooled analysis from the INHANCE consortium. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 23: 160-71. PMID 24351902 DOI: 10.1158/1055-9965.EPI-13-0181  0.32
2014 Leoncini E, Ricciardi W, Cadoni G, Arzani D, Petrelli L, Paludetti G, Brennan P, Luce D, Stucker I, Matsuo K, Talamini R, La Vecchia C, Olshan AF, Winn DM, Herrero R, ... ... Lazarus P, et al. Adult height and head and neck cancer: a pooled analysis within the INHANCE Consortium. European Journal of Epidemiology. 29: 35-48. PMID 24271556 DOI: 10.1007/s10654-013-9863-2  0.32
2013 Baldwin DA, Sarnowski CP, Reddy SA, Blair IA, Clapper M, Lazarus P, Li M, Muscat JE, Penning TM, Vachani A, Whitehead AS. Development of a genotyping microarray for studying the role of gene-environment interactions in risk for lung cancer. Journal of Biomolecular Techniques : Jbt. 24: 198-217. PMID 24294113 DOI: 10.7171/jbt.13-2404-004  0.32
2013 Ashmore JH, Lesko SM, Muscat JE, Gallagher CJ, Berg AS, Miller PE, Hartman TJ, Lazarus P. Association of dietary and supplemental folate intake and polymorphisms in three FOCM pathway genes with colorectal cancer in a population-based case-control study. Genes, Chromosomes & Cancer. 52: 945-53. PMID 23893618 DOI: 10.1002/gcc.22089  0.32
2013 Wyss A, Hashibe M, Chuang SC, Lee YC, Zhang ZF, Yu GP, Winn DM, Wei Q, Talamini R, Szeszenia-Dabrowska N, Sturgis EM, Smith E, Shangina O, Schwartz SM, Schantz S, ... ... Lazarus P, et al. Cigarette, cigar, and pipe smoking and the risk of head and neck cancers: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. American Journal of Epidemiology. 178: 679-90. PMID 23817919 DOI: 10.1093/aje/kwt029  0.32
2013 Sun D, Jones NR, Manni A, Lazarus P. Characterization of raloxifene glucuronidation: potential role of UGT1A8 genotype on raloxifene metabolism in vivo. Cancer Prevention Research (Philadelphia, Pa.). 6: 719-30. PMID 23682072 DOI: 10.1158/1940-6207.CAPR-12-0448  0.32
2013 Angstadt AY, Berg A, Zhu J, Miller P, Hartman TJ, Lesko SM, Muscat JE, Lazarus P, Gallagher CJ. The effect of copy number variation in the phase II detoxification genes UGT2B17 and UGT2B28 on colorectal cancer risk. Cancer. 119: 2477-85. PMID 23575887 DOI: 10.1002/cncr.28009  0.32
2013 Ashmore JH, Lesko SM, Miller PE, Cross AJ, Muscat JE, Zhu J, Liao J, Harper G, Lazarus P, Hartman TJ. Association of dietary and supplemental iron and colorectal cancer in a population-based study. European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (Ecp). 22: 506-11. PMID 23492957 DOI: 10.1097/CEJ.0b013e32836056f8  0.32
2013 Miller PE, Lazarus P, Lesko SM, Cross AJ, Sinha R, Laio J, Zhu J, Harper G, Muscat JE, Hartman TJ. Meat-related compounds and colorectal cancer risk by anatomical subsite. Nutrition and Cancer. 65: 202-26. PMID 23441608 DOI: 10.1080/01635581.2013.756534  0.32
2012 Brenner DR, Boffetta P, Duell EJ, Bickeböller H, Rosenberger A, McCormack V, Muscat JE, Yang P, Wichmann HE, Brueske-Hohlfeld I, Schwartz AG, Cote ML, Tjønneland A, Friis S, Le Marchand L, ... ... Lazarus P, et al. Previous lung diseases and lung cancer risk: a pooled analysis from the International Lung Cancer Consortium. American Journal of Epidemiology. 176: 573-85. PMID 22986146 DOI: 10.1093/aje/kws151  0.32
2012 Ma J, Xiao F, Xiong M, Andrew AS, Brenner H, Duell EJ, Haugen A, Hoggart C, Hung RJ, Lazarus P, Liu C, Matsuo K, Mayordomo JI, Schwartz AG, Staratschek-Jox A, et al. Natural and orthogonal interaction framework for modeling gene-environment interactions with application to lung cancer. Human Heredity. 73: 185-94. PMID 22889990 DOI: 10.1159/000339906  0.32
2012 Jones NR, Sun D, Freeman WM, Lazarus P. Quantification of Hepatic UDP glucuronosyltransferase 1A splice variant expression and correlation of UDP glucuronosyltransferase 1A1 variant expression with glucuronidation activity. The Journal of Pharmacology and Experimental Therapeutics. 342: 720-9. PMID 22661630 DOI: 10.1124/jpet.112.192658  0.32
2012 Erickson-Ridout KK, Sun D, Lazarus P. Glucuronidation of the second-generation antipsychotic clozapine and its active metabolite N-desmethylclozapine. Potential importance of the UGT1A1 A(TA)₇TAA and UGT1A4 L48V polymorphisms. Pharmacogenetics and Genomics. 22: 561-76. PMID 22565219 DOI: 10.1097/FPC.0b013e328354026b  0.48
2012 Coté ML, Liu M, Bonassi S, Neri M, Schwartz AG, Christiani DC, Spitz MR, Muscat JE, Rennert G, Aben KK, Andrew AS, Bencko V, Bickeböller H, Boffetta P, Brennan P, ... ... Lazarus P, et al. Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium. European Journal of Cancer (Oxford, England : 1990). 48: 1957-68. PMID 22436981 DOI: 10.1016/j.ejca.2012.01.038  0.32
2012 Chen G, Giambrone NE, Lazarus P. Glucuronidation of trans-3'-hydroxycotinine by UGT2B17 and UGT2B10. Pharmacogenetics and Genomics. 22: 183-90. PMID 22228205 DOI: 10.1097/FPC.0b013e32834ff3a5  0.32
2012 Chuang SC, Jenab M, Heck JE, Bosetti C, Talamini R, Matsuo K, Castellsague X, Franceschi S, Herrero R, Winn DM, La Vecchia C, Morgenstern H, Zhang ZF, Levi F, Dal Maso L, ... ... Lazarus P, et al. Diet and the risk of head and neck cancer: a pooled analysis in the INHANCE consortium. Cancer Causes & Control : Ccc. 23: 69-88. PMID 22037906 DOI: 10.1007/s10552-011-9857-x  0.32
2011 McCormack VA, Hung RJ, Brenner DR, Bickeböller H, Rosenberger A, Muscat JE, Lazarus P, Tjønneland A, Friis S, Christiani DC, Chun EM, Le Marchand L, Rennert G, Rennert HS, Andrew AS, et al. Aspirin and NSAID use and lung cancer risk: a pooled analysis in the International Lung Cancer Consortium (ILCCO). Cancer Causes & Control : Ccc. 22: 1709-20. PMID 21987079 DOI: 10.1007/s10552-011-9847-z  0.32
2011 Olson KC, Sun D, Chen G, Sharma AK, Amin S, Ropson IJ, Spratt TE, Lazarus P. Characterization of dibenzo[a,l]pyrene-trans-11,12-diol (dibenzo[def,p]chrysene) glucuronidation by UDP-glucuronosyltransferases. Chemical Research in Toxicology. 24: 1549-59. PMID 21780761 DOI: 10.1021/tx200178v  0.32
2011 Erickson-Ridout KK, Zhu J, Lazarus P. Olanzapine metabolism and the significance of UGT1A448V and UGT2B1067Y variants. Pharmacogenetics and Genomics. 21: 539-51. PMID 21750471 DOI: 10.1097/FPC.0b013e328348c76b  0.48
2011 Lubin JH, Muscat J, Gaudet MM, Olshan AF, Curado MP, Dal Maso L, Wünsch-Filho V, Sturgis EM, Szeszenia-Dabrowska N, Castellsague X, Zhang ZF, Smith E, Fernandez L, Matos E, Franceschi S, ... ... Lazarus P, et al. An examination of male and female odds ratios by BMI, cigarette smoking, and alcohol consumption for cancers of the oral cavity, pharynx, and larynx in pooled data from 15 case-control studies. Cancer Causes & Control : Ccc. 22: 1217-31. PMID 21744095 DOI: 10.1007/s10552-011-9792-x  0.32
2011 McKay JD, Truong T, Gaborieau V, Chabrier A, Chuang SC, Byrnes G, Zaridze D, Shangina O, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Bucur A, Bencko V, Holcatova I, ... ... Lazarus P, et al. A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. Plos Genetics. 7: e1001333. PMID 21437268 DOI: 10.1371/journal.pgen.1001333  0.32
2011 Chen D, Truong T, Gaborieau V, Byrnes G, Chabrier A, Chuang SC, Olshan AF, Weissler MC, Luo J, Romkes M, Buch S, Nukui T, Franceschi S, Herrero R, Talamini R, ... ... Lazarus P, et al. A sex-specific association between a 15q25 variant and upper aerodigestive tract cancers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 20: 658-64. PMID 21335511 DOI: 10.1158/1055-9965.EPI-10-1008  0.32
2011 Bushey RT, Chen G, Blevins-Primeau AS, Krzeminski J, Amin S, Lazarus P. Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis. Pharmacogenetics and Genomics. 21: 55-65. PMID 21164388 DOI: 10.1097/FPC.0b013e328341db05  0.32
2011 Jones NR, Spratt TE, Berg AS, Muscat JE, Lazarus P, Gallagher CJ. Association studies of excision repair cross-complementation group 1 (ERCC1) haplotypes with lung and head and neck cancer risk in a Caucasian population. Cancer Epidemiology. 35: 175-81. PMID 20863778 DOI: 10.1016/j.canep.2010.08.007  0.32
2010 Chen G, Giambrone NE, Dluzen DF, Muscat JE, Berg A, Gallagher CJ, Lazarus P. Glucuronidation genotypes and nicotine metabolic phenotypes: importance of functional UGT2B10 and UGT2B17 polymorphisms. Cancer Research. 70: 7543-52. PMID 20876810 DOI: 10.1158/0008-5472.CAN-09-4582  0.32
2010 Gallagher CJ, Balliet RM, Sun D, Chen G, Lazarus P. Sex differences in UDP-glucuronosyltransferase 2B17 expression and activity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 2204-9. PMID 20810538 DOI: 10.1124/dmd.110.035345  0.32
2010 Sun D, Chen G, Dellinger RW, Sharma AK, Lazarus P. Characterization of 17-dihydroexemestane glucuronidation: potential role of the UGT2B17 deletion in exemestane pharmacogenetics. Pharmacogenetics and Genomics. 20: 575-85. PMID 20697310 DOI: 10.1097/FPC.0b013e32833b04af  0.32
2010 Mikse OR, Blake DC, Jones NR, Sun YW, Amin S, Gallagher CJ, Lazarus P, Weisz J, Herzog CR. FOXO3 encodes a carcinogen-activated transcription factor frequently deleted in early-stage lung adenocarcinoma. Cancer Research. 70: 6205-15. PMID 20631076 DOI: 10.1158/0008-5472.CAN-09-4008  0.32
2010 Truong T, Hung RJ, Amos CI, Wu X, Bickeböller H, Rosenberger A, Sauter W, Illig T, Wichmann HE, Risch A, Dienemann H, Kaaks R, Yang P, Jiang R, Wiencke JK, ... ... Lazarus P, et al. Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. Journal of the National Cancer Institute. 102: 959-71. PMID 20548021 DOI: 10.1093/jnci/djq178  0.32
2010 Lubin JH, Gaudet MM, Olshan AF, Kelsey K, Boffetta P, Brennan P, Castellsague X, Chen C, Curado MP, Dal Maso L, Daudt AW, Fabianova E, Fernandez L, Wünsch-Filho V, Franceschi S, ... ... Lazarus P, et al. Body mass index, cigarette smoking, and alcohol consumption and cancers of the oral cavity, pharynx, and larynx: modeling odds ratios in pooled case-control data. American Journal of Epidemiology. 171: 1250-61. PMID 20494999 DOI: 10.1093/aje/kwq088  0.32
2010 Li Y, Ma C, Wang Z, Chen G, Ahn K, Lazarus P, Wu R. A disequilibrium model for detecting genetic mutations for cancer Journal of Theoretical Biology. 265: 218-224. PMID 20450921 DOI: 10.1016/j.jtbi.2010.04.019  0.32
2010 Miller PE, Lazarus P, Lesko SM, Muscat JE, Harper G, Cross AJ, Sinha R, Ryczak K, Escobar G, Mauger DT, Hartman TJ. Diet index-based and empirically derived dietary patterns are associated with colorectal cancer risk. The Journal of Nutrition. 140: 1267-73. PMID 20444952 DOI: 10.3945/jn.110.121780  0.32
2010 Miller PE, Lesko SM, Muscat JE, Lazarus P, Hartman TJ. Dietary patterns and colorectal adenoma and cancer risk: a review of the epidemiological evidence. Nutrition and Cancer. 62: 413-24. PMID 20432162 DOI: 10.1080/01635580903407114  0.32
2010 Gaudet MM, Olshan AF, Chuang SC, Berthiller J, Zhang ZF, Lissowska J, Zaridze D, Winn DM, Wei Q, Talamini R, Szeszenia-Dabrowska N, Sturgis EM, Schwartz SM, Rudnai P, Eluf-Neto J, ... ... Lazarus P, et al. Body mass index and risk of head and neck cancer in a pooled analysis of case-control studies in the International Head and Neck Cancer Epidemiology (INHANCE) Consortium. International Journal of Epidemiology. 39: 1091-102. PMID 20123951 DOI: 10.1093/ije/dyp380  0.32
2010 Truong T, Sauter W, McKay JD, Hosgood HD, Gallagher C, Amos CI, Spitz M, Muscat J, Lazarus P, Illig T, Wichmann HE, Bickeböller H, Risch A, Dienemann H, Zhang ZF, et al. International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants. Carcinogenesis. 31: 625-33. PMID 20106900 DOI: 10.1093/carcin/bgq001  0.32
2010 Balliet RM, Chen G, Dellinger RW, Lazarus P. UDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 484-90. PMID 20007297 DOI: 10.1124/dmd.109.030569  0.32
2010 Lazarus P, Sun D. Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen and aromatase inhibitors. Drug Metabolism Reviews. 42: 182-94. PMID 19821643 DOI: 10.3109/03602530903208652  0.48
2009 Lubin JH, Purdue M, Kelsey K, Zhang ZF, Winn D, Wei Q, Talamini R, Szeszenia-Dabrowska N, Sturgis EM, Smith E, Shangina O, Schwartz SM, Rudnai P, Neto JE, Muscat J, ... ... Lazarus P, et al. Total exposure and exposure rate effects for alcohol and smoking and risk of head and neck cancer: a pooled analysis of case-control studies. American Journal of Epidemiology. 170: 937-47. PMID 19745021 DOI: 10.1093/aje/kwp222  0.32
2009 Olson KC, Dellinger RW, Zhong Q, Sun D, Amin S, Spratt TE, Lazarus P. Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1999-2007. PMID 19589876 DOI: 10.1124/dmd.108.024596  0.32
2009 Berthiller J, Lee YC, Boffetta P, Wei Q, Sturgis EM, Greenland S, Morgenstern H, Zhang ZF, Lazarus P, Muscat J, Chen C, Schwartz SM, Eluf Neto J, Wünsch Filho V, Koifman S, et al. Marijuana smoking and the risk of head and neck cancer: pooled analysis in the INHANCE consortium. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 1544-51. PMID 19423532 DOI: 10.1158/1055-9965.EPI-08-0845  0.32
2009 Yang X, Liang SH, Weyant DM, Lazarus P, Gallagher CJ, Omiecinski CJ. The expression of human microsomal epoxide hydrolase is predominantly driven by a genetically polymorphic far upstream promoter. The Journal of Pharmacology and Experimental Therapeutics. 330: 23-30. PMID 19364907 DOI: 10.1124/jpet.109.150870  0.32
2009 Lazarus P, Blevins-Primeau AS, Zheng Y, Sun D. Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen. Annals of the New York Academy of Sciences. 1155: 99-111. PMID 19250197 DOI: 10.1111/j.1749-6632.2009.04114.x  0.48
2009 Hashibe M, Brennan P, Chuang SC, Boccia S, Castellsague X, Chen C, Curado MP, Dal Maso L, Daudt AW, Fabianova E, Fernandez L, Wünsch-Filho V, Franceschi S, Hayes RB, Herrero R, ... ... Lazarus P, et al. Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 541-50. PMID 19190158 DOI: 10.1158/1055-9965.EPI-08-0347  0.32
2009 Muscat JE, Chen G, Knipe A, Stellman SD, Lazarus P, Richie JP. Effects of menthol on tobacco smoke exposure, nicotine dependence, and NNAL glucuronidation. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 35-41. PMID 19124478 DOI: 10.1158/1055-9965.EPI-08-0744  0.32
2009 Gallagher CJ, Ahn K, Knipe AL, Dyer AM, Richie JP, Lazarus P, Muscat JE. Association between haplotypes of manganese superoxide dismutase (SOD2), smoking, and lung cancer risk. Free Radical Biology & Medicine. 46: 20-4. PMID 18930810 DOI: 10.1016/j.freeradbiomed.2008.09.018  0.32
2008 Hung RJ, Christiani DC, Risch A, Popanda O, Haugen A, Zienolddiny S, Benhamou S, Bouchardy C, Lan Q, Spitz MR, Wichmann HE, LeMarchand L, Vineis P, Matullo G, Kiyohara C, ... ... Lazarus P, et al. International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 3081-9. PMID 18990748 DOI: 10.1158/1055-9965.EPI-08-0411  0.32
2008 Chen G, Dellinger RW, Gallagher CJ, Sun D, Lazarus P. Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines. Pharmacogenetics and Genomics. 18: 181-91. PMID 18300939 DOI: 10.1097/FPC.0b013e3282f4dbdd  0.32
2008 Chen G, Dellinger RW, Sun D, Spratt TE, Lazarus P. Glucuronidation of tobacco-specific nitrosamines by UGT2B10. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 824-30. PMID 18238858 DOI: 10.1124/dmd.107.019406  0.32
2007 Gallagher CJ, Kadlubar FF, Muscat JE, Ambrosone CB, Lang NP, Lazarus P. The UGT2B17 gene deletion polymorphism and risk of prostate cancer. A case-control study in Caucasians. Cancer Detection and Prevention. 31: 310-5. PMID 17935910 DOI: 10.1016/j.cdp.2007.07.005  0.32
2007 Chen G, Blevins-Primeau AS, Dellinger RW, Muscat JE, Lazarus P. Glucuronidation of nicotine and cotinine by UGT2B10: loss of function by the UGT2B10 Codon 67 (Asp>Tyr) polymorphism. Cancer Research. 67: 9024-9. PMID 17909004 DOI: 10.1158/0008-5472.CAN-07-2245  0.32
2007 Sun D, Sharma AK, Dellinger RW, Blevins-Primeau AS, Balliet RM, Chen G, Boyiri T, Amin S, Lazarus P. Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 2006-14. PMID 17664247 DOI: 10.1124/dmd.107.017145  0.32
2007 Dellinger RW, Chen G, Blevins-Primeau AS, Krzeminski J, Amin S, Lazarus P. Glucuronidation of PhIP and N-OH-PhIP by UDP-glucuronosyltransferase 1A10. Carcinogenesis. 28: 2412-8. PMID 17638922 DOI: 10.1093/carcin/bgm164  0.32
2007 Zheng Y, Sun D, Sharma AK, Chen G, Amin S, Lazarus P. Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1942-8. PMID 17620345 DOI: 10.1124/dmd.107.016279  0.48
2007 Gallagher CJ, Muscat JE, Hicks AN, Zheng Y, Dyer AM, Chase GA, Richie J, Lazarus P. The UDP-glucuronosyltransferase 2B17 gene deletion polymorphism: sex-specific association with urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronidation phenotype and risk for lung cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 823-8. PMID 17416778 DOI: 10.1158/1055-9965.EPI-06-0823  0.32
2006 Sun D, Chen G, Dellinger RW, Duncan K, Fang JL, Lazarus P. Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants. Breast Cancer Research : Bcr. 8: R50. PMID 16884532 DOI: 10.1186/bcr1539  0.32
2006 Dellinger RW, Fang JL, Chen G, Weinberg R, Lazarus P. Importance of UDP-glucuronosyltransferase 1A10 (UGT1A10) in the detoxification of polycyclic aromatic hydrocarbons: decreased glucuronidative activity of the UGT1A10139Lys isoform. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 943-9. PMID 16510539 DOI: 10.1124/dmd.105.009100  0.32
2004 Park J, Chen L, Shade K, Lazarus P, Seigne J, Patterson S, Helal M, Pow-Sang J. Asp85tyr polymorphism in the udp-glucuronosyltransferase (UGT) 2B15 gene and the risk of prostate cancer. The Journal of Urology. 171: 2484-8. PMID 15126881 DOI: 10.1097/01.ju.0000117748.44313.43  0.32
2004 Smits KM, Benhamou S, Garte S, Weijenberg MP, Alamanos Y, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Boffetta P, Bouchardy C, Brockmoller J, Butkiewicz D, Cascorbi I, ... ... Lazarus P, et al. Association of metabolic gene polymorphisms with tobacco consumption in healthy controls. International Journal of Cancer. Journal International Du Cancer. 110: 266-70. PMID 15069692 DOI: 10.1002/ijc.20114  0.32
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