Lloyd C. Trotman - Publications

Affiliations: 
Molecular and Cellular Biology Stony Brook University, Stony Brook, NY, United States 
Area:
Molecular Biology, Cell Biology, Oncology

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Nowak DG, Katsenelson KC, Watrud KE, Chen M, Mathew G, D'Andrea VD, Lee MF, Swamynathan MM, Casanova-Salas I, Jibilian MC, Buckholtz CL, Ambrico AJ, Pan CH, Wilkinson JE, Newton AC, ... Trotman LC, et al. The PHLPP2 phosphatase is a druggable driver of prostate cancer progression. The Journal of Cell Biology. PMID 31092557 DOI: 10.1083/jcb.201902048  0.32
2018 Naguib A, Mathew G, Reczek CR, Watrud K, Ambrico A, Herzka T, Salas IC, Lee MF, El-Amine N, Zheng W, Di Francesco ME, Marszalek JR, Pappin DJ, Chandel NS, Trotman LC. Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells. Cell Reports. 23: 58-67. PMID 29617673 DOI: 10.1016/j.celrep.2018.03.032  0.52
2017 Alexander J, Kendall J, McIndoo J, Rodgers L, Aboukhalil R, Levy D, Stepansky A, Sun G, Chobadjiev L, Riggs M, Cox H, Hakker I, Nowak DG, Laze J, Llukani E, ... ... Trotman LC, et al. Utility of single cell genomics in diagnostic evaluation of prostate cancer. Cancer Research. PMID 29180472 DOI: 10.1158/0008-5472.CAN-17-1138  0.52
2017 Senturk S, Shirole NH, Nowak DG, Corbo V, Pal D, Vaughan A, Tuveson DA, Trotman LC, Kinney JB, Sordella R. Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization. Nature Communications. 8: 14370. PMID 28224990 DOI: 10.1038/ncomms14370  0.32
2017 Chen M, Nowak DG, Narula N, Robinson B, Watrud K, Ambrico A, Herzka TM, Zeeman ME, Minderer M, Zheng W, Ebbesen SH, Plafker KS, Stahlhut C, Wang VM, Wills L, ... ... Trotman LC, et al. The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. The Journal of Cell Biology. PMID 28193700 DOI: 10.1083/jcb.201604025  0.52
2016 Labbé DP, Uetani N, Vinette V, Lessard L, Aubry I, Migon E, Sirois J, Haigh JJ, Bégin LR, Trotman LC, Paquet M, Tremblay ML. PTP1B Deficiency Enables the Ability of a High-Fat Diet to Drive the Invasive Character of PTEN-Deficient Prostate Cancers. Cancer Research. PMID 27020859 DOI: 10.1158/0008-5472.CAN-15-1501  0.32
2015 Naguib A, Bencze G, Cho H, Zheng W, Tocilj A, Elkayam E, Faehnle CR, Jaber N, Pratt CP, Chen M, Zong WX, Marks MS, Joshua-Tor L, Pappin DJ, Trotman LC. PTEN functions by recruitment to cytoplasmic vesicles. Molecular Cell. 58: 255-68. PMID 25866245 DOI: 10.1016/j.molcel.2015.03.011  0.32
2015 Nowak DG, Cho H, Herzka T, Watrud K, DeMarco DV, Wang VM, Senturk S, Fellmann C, Ding D, Beinortas T, Kleinman D, Chen M, Sordella R, Wilkinson JE, Castillo-Martin M, ... ... Trotman LC, et al. MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Cancer Discovery. 5: 636-51. PMID 25829425 DOI: 10.1158/2159-8290.CD-14-1113  0.32
2015 Cho H, Herzka T, Stahlhut C, Watrud K, Robinson BD, Trotman LC. Rapid in vivo validation of candidate drivers derived from the PTEN-mutant prostate metastasis genome. Methods (San Diego, Calif.). 77: 197-204. PMID 25592467 DOI: 10.1016/j.ymeth.2014.12.022  0.52
2015 Naguib A, Bencze G, Engle DD, Chio II, Herzka T, Watrud K, Bencze S, Tuveson DA, Pappin DJ, Trotman LC. p53 mutations change phosphatidylinositol acyl chain composition. Cell Reports. 10: 8-19. PMID 25543136 DOI: 10.1016/j.celrep.2014.12.010  0.32
2014 Reyes G, Niederst M, Cohen-Katsenelson K, Stender JD, Kunkel MT, Chen M, Brognard J, Sierecki E, Gao T, Nowak DG, Trotman LC, Glass CK, Newton AC. Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output. Proceedings of the National Academy of Sciences of the United States of America. 111: E3957-65. PMID 25201979 DOI: 10.1073/pnas.1404221111  0.32
2014 Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, ... ... Trotman LC, et al. A unified nomenclature and amino acid numbering for human PTEN. Science Signaling. 7: pe15. PMID 24985344 DOI: 10.1126/scisignal.2005560  0.32
2014 Chen M, Nowak DG, Trotman LC. Molecular pathways: PI3K pathway phosphatases as biomarkers for cancer prognosis and therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3057-63. PMID 24928944 DOI: 10.1158/1078-0432.CCR-12-3680  0.32
2014 Cho H, Herzka T, Zheng W, Qi J, Wilkinson JE, Bradner JE, Robinson BD, Castillo-Martin M, Cordon-Cardo C, Trotman LC. RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis. Cancer Discovery. 4: 318-333. PMID 24444712 DOI: 10.1158/2159-8290.CD-13-0346  0.32
2014 Labbé DP, Nowak DG, Deblois G, Lessard L, Giguère V, Trotman LC, Tremblay ML. Prostate cancer genetic-susceptibility locus on chromosome 20q13 is amplified and coupled to androgen receptor-regulation in metastatic tumors. Molecular Cancer Research : McR. 12: 184-9. PMID 24379448 DOI: 10.1158/1541-7786.MCR-13-0477  0.32
2012 Xiong Q, Oviedo HV, Trotman LC, Zador AM. PTEN regulation of local and long-range connections in mouse auditory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1643-52. PMID 22302806 DOI: 10.1523/JNEUROSCI.4480-11.2012  0.32
2012 Lessard L, Labbé DP, Deblois G, Bégin LR, Hardy S, Mes-Masson AM, Saad F, Trotman LC, Giguère V, Tremblay ML. PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer. Cancer Research. 72: 1529-37. PMID 22282656 DOI: 10.1158/0008-5472.CAN-11-2602  0.32
2012 Howitt J, Lackovic J, Low LH, Naguib A, Macintyre A, Goh CP, Callaway JK, Hammond V, Thomas T, Dixon M, Putz U, Silke J, Bartlett P, Yang B, Kumar S, ... Trotman LC, et al. Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia. The Journal of Cell Biology. 196: 29-36. PMID 22213801 DOI: 10.1083/jcb.201105009  0.32
2011 Chen M, Pratt CP, Zeeman ME, Schultz N, Taylor BS, O'Neill A, Castillo-Martin M, Nowak DG, Naguib A, Grace DM, Murn J, Navin N, Atwal GS, Sander C, Gerald WL, ... ... Trotman LC, et al. Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression. Cancer Cell. 20: 173-86. PMID 21840483 DOI: 10.1016/j.ccr.2011.07.013  0.32
2010 Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, ... ... Trotman LC, et al. Towards patient-based cancer therapeutics. Nature Biotechnology. 28: 904-6. PMID 20829823 DOI: 10.1038/nbt0910-904  0.32
2010 Alimonti A, Nardella C, Chen Z, Clohessy JG, Carracedo A, Trotman LC, Cheng K, Varmeh S, Kozma SC, Thomas G, Rosivatz E, Woscholski R, Cognetti F, Scher HI, Pandolfi PP. A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis Journal of Clinical Investigation. 120: 681-693. PMID 20197621 DOI: 10.1172/JCI40535  0.32
2008 Janas ML, Hodson D, Stamataki Z, Hill S, Welch K, Gambardella L, Trotman LC, Pandolfi PP, Vigorito E, Turner M. The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 739-46. PMID 18178811  0.32
2007 Trotman LC, Wang X, Alimonti A, Chen Z, Teruya-Feldstein J, Yang H, Pavletich NP, Carver BS, Cordon-Cardo C, Erdjument-Bromage H, Tempst P, Chi SG, Kim HJ, Misteli T, Jiang X, et al. Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression Cell. 128: 141-156. PMID 17218261 DOI: 10.1016/j.cell.2006.11.040  0.32
2006 Trotman LC, Alimonti A, Scaglioni PP, Koutcher JA, Cordon-Cardo C, Pandolfi PP. Identification of a tumour suppressor network opposing nuclear Akt function. Nature. 441: 523-7. PMID 16680151 DOI: 10.1038/nature04809  0.32
2004 Steffan JS, Agrawal N, Pallos J, Rockabrand E, Trotman LC, Slepko N, Illes K, Lukacsovich T, Zhu YZ, Cattaneo E, Pandolfi PP, Thompson LM, Marsh JL. SUMO modification of Huntingtin and Huntington's disease pathology. Science (New York, N.Y.). 304: 100-4. PMID 15064418 DOI: 10.1126/science.1092194  0.32
2003 Trotman LC, Niki M, Dotan ZA, Koutcher JA, Di Cristofano A, Xiao A, Khoo AS, Roy-Burman P, Greenberg NM, Van Dyke T, Cordon-Cardo C, Pandolfi PP. Pten dose dictates cancer progression in the prostate. Plos Biology. 1: E59. PMID 14691534 DOI: 10.1371/journal.pbio.0000059  0.32
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