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Lawrence B. Gardner - Publications

Affiliations: 
Basic Medical Science New York University, New York, NY, United States 
Area:
Cell Biology
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Daley D, Mani VR, Mohan N, Akkad N, Ochi A, Heindel DW, Lee KB, Zambirinis CP, Pandian GS, Savadkar S, Torres-Hernandez A, Nayak S, Wang D, Hundeyin M, Diskin B, ... ... Gardner L, et al. Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance. Nature Medicine. PMID 28394331 DOI: 10.1038/Nm.4314  0.307
2015 Wengrod JC, Gardner LB. Cellular adaptation to nutrient deprivation: crosstalk between the mTORC1 and eIF2α signaling pathways and implications for autophagy. Cell Cycle (Georgetown, Tex.). 14: 2571-7. PMID 26039820 DOI: 10.1080/15384101.2015.1056947  0.733
2015 Wengrod J, Wang D, Weiss S, Zhong H, Osman I, Gardner LB. Phosphorylation of eIF2α triggered by mTORC1 inhibition and PP6C activation is required for autophagy and is aberrant in PP6C-mutated melanoma. Science Signaling. 8: ra27. PMID 25759478 DOI: 10.1126/Scisignal.Aaa0899  0.738
2014 Martin L, Gardner LB. Stress-induced inhibition of nonsense-mediated RNA decay regulates intracellular cystine transport and intracellular glutathione through regulation of the cystine/glutamate exchanger SLC7A11. Oncogene. PMID 25399695 DOI: 10.1038/Onc.2014.352  0.402
2014 Martin L, Grigoryan A, Wang D, Wang J, Breda L, Rivella S, Cardozo T, Gardner LB. Identification and characterization of small molecules that inhibit nonsense-mediated RNA decay and suppress nonsense p53 mutations. Cancer Research. 74: 3104-13. PMID 24662918 DOI: 10.1158/0008-5472.Can-13-2235  0.49
2014 Gold HL, Wengrod J, de Miera EV, Wang D, Fleming N, Sikkema L, Kirchhoff T, Hochman T, Goldberg JD, Osman I, Gardner LB. PP6C hotspot mutations in melanoma display sensitivity to Aurora kinase inhibition. Molecular Cancer Research : McR. 12: 433-9. PMID 24336958 DOI: 10.1158/1541-7786.Mcr-13-0422  0.717
2013 Wengrod J, Martin L, Wang D, Frischmeyer-Guerrerio P, Dietz HC, Gardner LB. Inhibition of nonsense-mediated RNA decay activates autophagy. Molecular and Cellular Biology. 33: 2128-35. PMID 23508110 DOI: 10.1128/Mcb.00174-13  0.751
2013 Karam R, Wengrod J, Gardner LB, Wilkinson MF. Regulation of nonsense-mediated mRNA decay: implications for physiology and disease. Biochimica Et Biophysica Acta. 1829: 624-33. PMID 23500037 DOI: 10.1016/J.Bbagrm.2013.03.002  0.728
2013 Gold HL, Wengrod J, Tian J, Miera EVd, Nadeem Z, Fleming NH, Shapiro R, Hernando-Monge E, Gardner L, Osman I. The clinical and biologic impact of PPP6C mutations in melanoma. Journal of Clinical Oncology. 31: 9067-9067. DOI: 10.1200/Jco.2013.31.15_Suppl.9067  0.7
2012 Martin L, Rainey M, Santocanale C, Gardner LB. Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation. Oncogene. 31: 4076-84. PMID 22179839 DOI: 10.1038/Onc.2011.585  0.372
2011 Wang D, Wengrod J, Gardner LB. Overexpression of the c-myc oncogene inhibits nonsense-mediated RNA decay in B lymphocytes. The Journal of Biological Chemistry. 286: 40038-43. PMID 21969377 DOI: 10.1074/Jbc.M111.266361  0.737
2011 Wang D, Zavadil J, Martin L, Parisi F, Friedman E, Levy D, Harding H, Ron D, Gardner LB. Inhibition of nonsense-mediated RNA decay by the tumor microenvironment promotes tumorigenesis. Molecular and Cellular Biology. 31: 3670-80. PMID 21730287 DOI: 10.1128/Mcb.05704-11  0.503
2011 Chin KT, Kang G, Qu J, Gardner LB, Coetzee WA, Zito E, Fishman GI, Ron D. The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2583-91. PMID 21507899 DOI: 10.1096/Fj.11-184622  0.306
2010 Martin L, Kimball SR, Gardner LB. Regulation of the unfolded protein response by eif2Bdelta isoforms. The Journal of Biological Chemistry. 285: 31944-53. PMID 20709751 DOI: 10.1074/Jbc.M110.153148  0.443
2010 Gardner LB. Nonsense-mediated RNA decay regulation by cellular stress: implications for tumorigenesis. Molecular Cancer Research : McR. 8: 295-308. PMID 20179151 DOI: 10.1158/1541-7786.Mcr-09-0502  0.537
2009 Breda L, Casu C, Casula L, Kleinert DA, Bianchi N, Prus E, Cartegni L, Fibach E, Gardner LB, Giardina PJ, Gambari R, Rivella S. Following Beta-Globin Gene Transfer, the Production of Hemoglobin Depends Upon the Beta-Thalassemia Genotype. Blood. 114: 978-978. DOI: 10.1182/Blood.V114.22.978.978  0.327
2008 Gardner LB, Corn PG. Hypoxic regulation of mRNA expression. Cell Cycle (Georgetown, Tex.). 7: 1916-24. PMID 18604161 DOI: 10.4161/Cc.7.13.6203  0.466
2008 Gardner LB. Hypoxic inhibition of nonsense-mediated RNA decay regulates gene expression and the integrated stress response. Molecular and Cellular Biology. 28: 3729-41. PMID 18362164 DOI: 10.1128/Mcb.02284-07  0.53
2007 Clancy RM, Zheng P, O'Mahony M, Izmirly P, Zavadil J, Gardner L, Buyon JP. Role of hypoxia and cAMP in the transdifferentiation of human fetal cardiac fibroblasts: implications for progression to scarring in autoimmune-associated congenital heart block. Arthritis & Rheumatism. 56: 4120-4131. PMID 18050204 DOI: 10.1002/Art.23061  0.308
2007 Nemetski SM, Gardner LB. Hypoxic regulation of Id-1 and activation of the unfolded protein response are aberrant in neuroblastoma. The Journal of Biological Chemistry. 282: 240-8. PMID 17102133 DOI: 10.1074/Jbc.M607275200  0.405
2007 Gardner LB. Inhibition of Nonsense Mediated RNA Decay in Hypoxic Cells; Implications for Thalassemia. Blood. 110: 1781-1781. DOI: 10.1182/Blood.V110.11.1781.1781  0.562
2005 Kim JW, Gardner LB, Dang CV. Oncogenic alterations of metabolism and the Warburg effect Drug Discovery Today: Disease Mechanisms. 2: 233-238. DOI: 10.1016/J.Ddmec.2005.04.001  0.366
2003 Gardner LB, Li F, Yang X, Dang CV. Anoxic fibroblasts activate a replication checkpoint that is bypassed by E1a. Molecular and Cellular Biology. 23: 9032-45. PMID 14645516 DOI: 10.1128/Mcb.23.24.9032-9045.2003  0.349
2001 Gardner LB, Li Q, Park MS, Flanagan WM, Semenza GL, Dang CV. Hypoxia Inhibits G1/S Transition through Regulation of p27 Expression Journal of Biological Chemistry. 276: 7919-7926. PMID 11112789 DOI: 10.1074/Jbc.M010189200  0.373
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