Year |
Citation |
Score |
2015 |
Wengrod JC, Gardner LB. Cellular adaptation to nutrient deprivation: crosstalk between the mTORC1 and eIF2α signaling pathways and implications for autophagy. Cell Cycle (Georgetown, Tex.). 14: 2571-7. PMID 26039820 DOI: 10.1080/15384101.2015.1056947 |
0.48 |
|
2015 |
Wengrod J, Wang D, Weiss S, Zhong H, Osman I, Gardner LB. Phosphorylation of eIF2α triggered by mTORC1 inhibition and PP6C activation is required for autophagy and is aberrant in PP6C-mutated melanoma. Science Signaling. 8: ra27. PMID 25759478 DOI: 10.1126/scisignal.aaa0899 |
0.48 |
|
2014 |
Martin L, Grigoryan A, Wang D, Wang J, Breda L, Rivella S, Cardozo T, Gardner LB. Identification and characterization of small molecules that inhibit nonsense-mediated RNA decay and suppress nonsense p53 mutations. Cancer Research. 74: 3104-13. PMID 24662918 DOI: 10.1158/0008-5472.CAN-13-2235 |
0.48 |
|
2014 |
Gold HL, Wengrod J, de Miera EV, Wang D, Fleming N, Sikkema L, Kirchhoff T, Hochman T, Goldberg JD, Osman I, Gardner LB. PP6C hotspot mutations in melanoma display sensitivity to Aurora kinase inhibition. Molecular Cancer Research : McR. 12: 433-9. PMID 24336958 DOI: 10.1158/1541-7786.MCR-13-0422 |
0.48 |
|
2013 |
Karam R, Wengrod J, Gardner LB, Wilkinson MF. Regulation of nonsense-mediated mRNA decay: implications for physiology and disease. Biochimica Et Biophysica Acta. 1829: 624-33. PMID 23500037 DOI: 10.1016/j.bbagrm.2013.03.002 |
0.48 |
|
2012 |
Breda L, Casu C, Gardenghi S, Bianchi N, Cartegni L, Narla M, Yazdanbakhsh K, Musso M, Manwani D, Little J, Gardner LB, Kleinert DA, Prus E, Fibach E, Grady RW, et al. Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients. Plos One. 7: e32345. PMID 22479321 DOI: 10.1371/journal.pone.0032345 |
0.48 |
|
2011 |
Parathath S, Mick SL, Feig JE, Joaquin V, Grauer L, Habiel DM, Gassmann M, Gardner LB, Fisher EA. Hypoxia is present in murine atherosclerotic plaques and has multiple adverse effects on macrophage lipid metabolism. Circulation Research. 109: 1141-52. PMID 21921268 DOI: 10.1161/CIRCRESAHA.111.246363 |
0.48 |
|
2011 |
Wang D, Zavadil J, Martin L, Parisi F, Friedman E, Levy D, Harding H, Ron D, Gardner LB. Inhibition of nonsense-mediated RNA decay by the tumor microenvironment promotes tumorigenesis. Molecular and Cellular Biology. 31: 3670-80. PMID 21730287 DOI: 10.1128/MCB.05704-11 |
0.48 |
|
2011 |
Chin KT, Kang G, Qu J, Gardner LB, Coetzee WA, Zito E, Fishman GI, Ron D. The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2583-91. PMID 21507899 DOI: 10.1096/fj.11-184622 |
0.48 |
|
2008 |
Amengual JE, Zhang X, Ibrahim S, Gardner LB. Regression of HIV-related diffuse large B-cell lymphoma in response to antiviral therapy alone. Blood. 112: 4359-60. PMID 18988884 DOI: 10.1182/blood-2008-06-162289 |
0.48 |
|
2008 |
Asmis LM, Segal JB, Plantinga LC, Fink NE, Kerman JS, Kickler TS, Coresh J, Gardner LB. Heparin-induced antibodies and cardiovascular risk in patients on dialysis. Thrombosis and Haemostasis. 100: 498-504. PMID 18766268 DOI: 10.1160/TH08-03-0144 |
0.48 |
|
2007 |
Nemetski SM, Gardner LB. Hypoxic regulation of Id-1 and activation of the unfolded protein response are aberrant in neuroblastoma. The Journal of Biological Chemistry. 282: 240-8. PMID 17102133 DOI: 10.1074/jbc.M607275200 |
0.48 |
|
2006 |
Dang DT, Chen F, Gardner LB, Cummins JM, Rago C, Bunz F, Kantsevoy SV, Dang LH. Hypoxia-inducible factor-1alpha promotes nonhypoxia-mediated proliferation in colon cancer cells and xenografts. Cancer Research. 66: 1684-936. PMID 16452228 DOI: 10.1158/0008-5472.CAN-05-2887 |
0.48 |
|
2005 |
Kim JW, Gardner LB, Dang CV. Oncogenic alterations of metabolism and the Warburg effect Drug Discovery Today: Disease Mechanisms. 2: 233-238. DOI: 10.1016/j.ddmec.2005.04.001 |
0.48 |
|
2003 |
Gardner LB, Li F, Yang X, Dang CV. Anoxic fibroblasts activate a replication checkpoint that is bypassed by E1a. Molecular and Cellular Biology. 23: 9032-45. PMID 14645516 DOI: 10.1128/MCB.23.24.9032-9045.2003 |
0.48 |
|
2001 |
Gardner LB, Li Q, Park MS, Flanagan WM, Semenza GL, Dang CV. Hypoxia Inhibits G1/S Transition through Regulation of p27 Expression Journal of Biological Chemistry. 276: 7919-7926. PMID 11112789 DOI: 10.1074/jbc.M010189200 |
0.48 |
|
1998 |
Dang CV, Gardner LB. Transient global amnesia after sex [17] Lancet. 352: 1557-1558. PMID 9820339 DOI: 10.1016/S0140-6736(05)60376-5 |
0.48 |
|
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