Haidong Dong - Publications

Affiliations: 
Immunology College of Medicine - Mayo Clinic 
Area:
Immunology, Cell Biology, Oncology

162 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bansal A, Lavoie RR, Lucien F, Kethamreddy M, Wootla B, Dong H, Park SS, Pandey MK. Synthesis and evaluation of anti-PD-L1-B11 antibody fragments for PET imaging of PD-L1 in breast cancer and melanoma tumor models. Scientific Reports. 14: 19561. PMID 39174596 DOI: 10.1038/s41598-024-70385-8  0.362
2023 Gicobi JK, Mao Z, DeFranco G, Hirdler JB, Li Y, Vianzon VV, Dellacecca ER, Hsu MA, Barham W, Yan Y, Mansfield AS, Lin Y, Wu X, Hitosugi T, Owen D, ... ... Dong H, et al. Salvage therapy expands highly cytotoxic and metabolically fit resilient CD8 T cells via ME1 up-regulation. Science Advances. 9: eadi2414. PMID 37967193 DOI: 10.1126/sciadv.adi2414  0.409
2023 Zheng J, Wang L, Zhao S, Zhang W, Chang Y, Bosco DB, Huang T, Dheer A, Gao S, Xu S, Ayasoufi K, Al-Kharboosh R, Qi F, Xie M, Johnson AJ, ... Dong H, et al. TREM2 mediates MHCII-associated CD4+ T cell response against gliomas. Neuro-Oncology. PMID 37941134 DOI: 10.1093/neuonc/noad214  0.364
2023 Zhong W, Lu Y, Han X, Yang J, Qin Z, Zhang W, Yu Z, Wu B, Liu S, Xu W, Zheng C, Schuchter LM, Karakousis GC, Mitchell TC, Amaravadi R, ... ... Dong H, et al. Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity. Cell Reports. 42: 113224. PMID 37805922 DOI: 10.1016/j.celrep.2023.113224  0.443
2023 Rodrigues Pessoa R, Zhang H, Zganjar A, Nabavizadeh R, Packiam VT, Lohse CM, Cheville JC, Pagliaro LC, Costello BA, Boorjian SA, Thompson RH, Lucien F, Dong H, Leibovich BC. Circulating antigen-primed cytotoxic T-cells in patients with renal tumors treated with surgery. Urologic Oncology. PMID 37414595 DOI: 10.1016/j.urolonc.2023.05.009  0.339
2023 Liu X, Aneas I, Sakabe N, Anderson RL, Billstrand C, Paz C, Kaur H, Furner B, Choi S, Prichina AY, Enninga EAL, Dong H, Murtha A, Crawford GE, Kessler JA, et al. Single cell profiling at the maternal-fetal interface reveals a deficiency of PD-L1 non-immune cells in human spontaneous preterm labor. Scientific Reports. 13: 7903. PMID 37193763 DOI: 10.1038/s41598-023-35051-5  0.34
2023 An Z, Hsu MA, Gicobi JK, Xu T, Harrington SM, Zhang H, Pavelko KD, Hirdler JB, Lohse CM, Nabavizadeh R, Pessoa RR, Sharma V, Thompson RH, Leibovich BC, Dong H, et al. A Novel PD-L1 Antibody Promotes Antitumor Function of Peripheral Cytotoxic Lymphocytes after Radical Nephrectomy in Patients with Renal Cell Carcinoma. Journal of Immunology (Baltimore, Md. : 1950). PMID 37163328 DOI: 10.4049/jimmunol.2200933  0.459
2023 Zheng J, Wang L, Zhao S, Zhang W, Chang Y, Dheer A, Gao S, Xu S, Ayasoufi K, Al-Kharboosh R, Xie M, Johnson AJ, Dong H, Qui Ones-Hinojosa A, Wu LJ. TREM2 mediates MHCII-associated CD4 T cell response against gliomas. Biorxiv : the Preprint Server For Biology. PMID 37066234 DOI: 10.1101/2023.04.05.535697  0.399
2023 Barham W, Hsu M, Liu X, Harrington SM, Hirdler JB, Gicobi JK, Zhu X, Zeng H, Pavelko KD, Yan Y, Mansfield AS, Dong H. A Novel Humanized PD-1/PD-L1 Mouse Model Permits Direct Comparison of Antitumor Immunity Generated by Food and Drug Administration-Approved PD-1 and PD-L1 Inhibitors. Immunohorizons. 7: 125-139. PMID 36656137 DOI: 10.4049/immunohorizons.2200054  0.41
2022 Gicobi JK, Dellacecca ER, Dong H. Resilient T-cell responses in patients with advanced cancers. International Journal of Hematology. PMID 35864292 DOI: 10.1007/s12185-022-03424-7  0.322
2022 Mahmoud AM, Frank I, Orme JJ, Lavoie RR, Thapa P, Costello BA, Cheville JC, Gupta S, Dong H, Lucien F. Evaluation of PD-L1 and B7-H3 expression as a predictor of response to adjuvant chemotherapy in bladder cancer. Bmc Urology. 22: 90. PMID 35751046 DOI: 10.1186/s12894-022-01044-1  0.431
2022 Friedman DJ, Kizerwetter M, Belmonte P, Rajcula M, Theodore K, Kim Lee HS, Shapiro MJ, Dong H, Shapiro VS. Cutting Edge: Enhanced Antitumor Immunity in ST8Sia6 Knockout Mice. Journal of Immunology (Baltimore, Md. : 1950). 208: 1845-1850. PMID 35379746 DOI: 10.4049/jimmunol.2101165  0.342
2022 Zhu M, Zhang H, Pedersen KS, Foster NR, Jaszewski BL, Liu X, Hirdler JB, An Z, Bekaii-Saab TS, Halfdanarson TR, Boland PM, Yan Y, Hubbard JH, Ma WW, Yoon HH, ... ... Dong H, et al. Understanding Suboptimal Response to Immune Checkpoint Inhibitors. Advanced Biology. e2101319. PMID 35343107 DOI: 10.1002/adbi.202101319  0.363
2022 Sun L, Wang Y, Wang X, Navarro-Corcuera A, Ilyas S, Jalan-Sakrikar N, Gan C, Tu X, Shi Y, Tu K, Liu Q, Lou Z, Dong H, Sharpe AH, Shah VH, et al. PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II. Cell Reports. 38: 110349. PMID 35139382 DOI: 10.1016/j.celrep.2022.110349  0.331
2022 Zhang W, Zhong W, Wang B, Yang J, Yang J, Yu Z, Qin Z, Shi A, Xu W, Zheng C, Schuchter LM, Karakousis GC, Mitchell TC, Amaravadi R, Herlyn M, ... Dong H, et al. ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression. Developmental Cell. PMID 35085484 DOI: 10.1016/j.devcel.2022.01.002  0.458
2021 Wen T, Barham W, Li Y, Zhang H, Gicobi JK, Hirdler JB, Liu X, Ham H, Peterson Martinez KE, Lucien F, Lavoie RR, Li H, Correia C, Monie DD, An Z, ... ... Dong H, et al. NKG7 is a T-cell intrinsic therapeutic target for improving antitumor cytotoxicity and cancer immunotherapy. Cancer Immunology Research. PMID 34911739 DOI: 10.1158/2326-6066.CIR-21-0539  0.476
2021 Lavoie RR, Gargollo PC, Ahmed ME, Kim Y, Baer E, Phelps DA, Charlesworth CM, Madden BJ, Wang L, Houghton PJ, Cheville J, Dong H, Granberg CF, Lucien F. Surfaceome Profiling of Rhabdomyosarcoma Reveals B7-H3 as a Mediator of Immune Evasion. Cancers. 13. PMID 34572755 DOI: 10.3390/cancers13184528  0.42
2021 Bansal A, Pandey MK, Barham W, Liu X, Harrington SM, Lucien F, Dong H, Park SS, DeGrado TR. Non-invasive immunoPET imaging of PD-L1 using anti-PD-L1-B11 in breast cancer and melanoma tumor model. Nuclear Medicine and Biology. 100: 4-11. PMID 34119742 DOI: 10.1016/j.nucmedbio.2021.05.004  0.347
2021 Wang Y, Sinha S, Wellik LE, Secreto CR, Rech KL, Call TG, Parikh SA, Kenderian SS, Muchtar E, Hayman SR, Koehler AB, Van Dyke DL, Leis JF, Slager SL, Dong H, et al. Distinct immune signatures in chronic lymphocytic leukemia and Richter syndrome. Blood Cancer Journal. 11: 86. PMID 33972504 DOI: 10.1038/s41408-021-00477-5  0.358
2021 Chen C, Li S, Xue J, Qi M, Liu X, Huang Y, Hu J, Dong H, Ling K. PD-L1 tumor-intrinsic signaling and its therapeutic implication in triple-negative breast cancer. Jci Insight. 6. PMID 33884962 DOI: 10.1172/jci.insight.131458  0.352
2020 Barham W, Guo R, Park SS, Herrmann J, Dong H, Yan Y. Case Report: Simultaneous Hyperprogression and Fulminant Myocarditis in a Patient With Advanced Melanoma Following Treatment With Immune Checkpoint Inhibitor Therapy. Frontiers in Immunology. 11: 561083. PMID 33603731 DOI: 10.3389/fimmu.2020.561083  0.468
2020 Breen WG, Leventakos K, Dong H, Merrell KW. Radiation and immunotherapy: emerging mechanisms of synergy. Journal of Thoracic Disease. 12: 7011-7023. PMID 33282406 DOI: 10.21037/Jtd-2019-Cptn-07  0.438
2020 Orme JJ, Enninga EAL, Lucien-Matteoni F, Dale H, Burgstaler E, Harrington SM, Ball MK, Mansfield AS, Park SS, Block MS, Markovic SN, Yan Y, Dong H, Dronca RS, Winters JL. Therapeutic plasma exchange clears circulating soluble PD-L1 and PD-L1-positive extracellular vesicles. Journal For Immunotherapy of Cancer. 8. PMID 32817395 DOI: 10.1136/Jitc-2020-001113  0.404
2020 Loeuillard E, Yang J, Buckarma E, Wang J, Liu Y, Conboy CB, Pavelko KD, Li Y, O'Brien D, Wang C, Graham RP, Smoot RL, Dong H, Rizvi S. Targeting tumor-associated macrophages and granulocytic-myeloid-derived suppressor cells augments pd-1 blockade in cholangiocarcinoma. The Journal of Clinical Investigation. PMID 32663198 DOI: 10.1172/Jci137110  0.485
2020 Yu J, Qin B, Moyer AM, Nowsheen S, Tu X, Dong H, Boughey JC, Goetz MP, Weinshilboum R, Lou Z, Wang L. Author Correction: Regulation of sister chromatid cohesion by nuclear PD-L1. Cell Research. PMID 32636455 DOI: 10.1038/S41422-020-0365-Y  0.36
2020 Vera Aguilera J, Paludo J, McWilliams RR, Zhang H, Li Y, Kumar AB, Failing J, Kottschade LA, Block MS, Markovic SN, Dong H, Dronca RS, Yan Y. Chemo-immunotherapy combination after PD-1 inhibitor failure improves clinical outcomes in metastatic melanoma patients. Melanoma Research. PMID 32404734 DOI: 10.1200/Jco.2018.36.15_Suppl.9558  0.485
2020 Orme JJ, Jazieh KA, Xie T, Harrington S, Liu X, Ball M, Madden B, Charlesworth MC, Azam TU, Lucien F, Wootla B, Li Y, Villasboas JC, Mansfield AS, Dronca RS, ... Dong H, et al. ADAM10 and ADAM17 cleave PD-L1 to mediate PD-(L)1 inhibitor resistance. Oncoimmunology. 9: 1744980. PMID 32363112 DOI: 10.1080/2162402X.2020.1744980  0.467
2020 Yu J, Qin B, Moyer AM, Nowsheen S, Tu X, Dong H, Boughey JC, Goetz MP, Weinshilboum R, Lou Z, Wang L. Regulation of sister chromatid cohesion by nuclear PD-L1. Cell Research. PMID 32350394 DOI: 10.1038/S41422-020-0315-8  0.493
2020 Johnson RMG, Wen T, Dong H. Bidirectional signals of PD-L1 in T cells that fraternize with cancer cells. Nature Immunology. PMID 32152507 DOI: 10.1038/S41590-020-0599-3  0.53
2020 Himes BT, Peterson TE, de Mooij T, Garcia MLMC, Jung MY, Uhm S, Yan D, Tyson J, Li HJL, Parney D, Abukhadra M, Gustafson MP, Dietz AB, Johnson AJ, Dong H, et al. The role of extracellular vesicles and PD-L1 in glioblastoma-mediated immunosuppressive monocyte induction. Neuro-Oncology. PMID 32080744 DOI: 10.1093/Neuonc/Noaa029  0.447
2020 Li C, Zhu B, Son YM, Wang Z, Jiang L, Xiang M, Ye Z, Beckermann KE, Wu Y, Jenkins JW, Siska PJ, Vincent BG, Prakash YS, Peikert T, Edelson BT, ... ... Dong H, et al. The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8 T Cell Fitness and Functionality. Immunity. 52: 201-202. PMID 31940270 DOI: 10.1016/J.Immuni.2019.12.008  0.359
2020 Packiam VT, Bhindi B, Zhang H, Lohse CM, Shah PH, Tsivian M, Pagliaro LC, Costello BA, Thompson RH, Boorjian SA, Cheville J, Dong H, Leibovich BC. The impact of surgical resection on circulating tumor-reactive cytotoxic T cells for patients with renal tumors. Journal of Clinical Oncology. 38: 725-725. DOI: 10.1200/Jco.2020.38.6_Suppl.725  0.398
2020 Zhu M, Zhang H, Foster NR, Dong H, Bekaii-Saab TS, Jaszewski BL, Boland PM, Overman MJ, Pedersen K, McWilliams RR, Academic. Abstract 4467: Bim and CX3CR1/granzyme B in circulating CD8+ T cells are predictive biomarkers for PD-1 blockade therapy Immunology. DOI: 10.1158/1538-7445.Am2020-4467  0.532
2019 Eckel-Passow JE, Ho TH, Serie DJ, Cheville JC, Houston Thompson R, Costello BA, Dong H, Kwon ED, Leibovich BC, Parker AS. Concordance of PD-1 and PD-L1 (B7-H1) in paired primary and metastatic clear cell renal cell carcinoma. Cancer Medicine. PMID 31829518 DOI: 10.1002/Cam4.2769  0.504
2019 Li C, Zhu B, Son YM, Wang Z, Jiang L, Xiang M, Ye Z, Beckermann KE, Wu Y, Jenkins JW, Siska PJ, Vincent BG, Prakash YS, Peikert T, Edelson BT, ... ... Dong H, et al. The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8 T Cell Fitness and Functionality. Immunity. 51: 491-507.e7. PMID 31533057 DOI: 10.1016/J.Immuni.2019.08.013  0.506
2019 Feng D, Qin B, Pal K, Sun L, Dutta S, Dong H, Liu X, Mukhopadhyay D, Huang S, Sinicrope FA. BRAF-induced, tumor intrinsic PD-L1 can regulate chemotherapy-induced apoptosis in human colon cancer cells and in tumor xenografts. Oncogene. PMID 31406255 DOI: 10.1038/S41388-019-0919-Y  0.475
2019 Sideras K, de Man RA, Harrington SM, Polak WG, Zhou G, Schutz HM, Pedroza-Gonzalez A, Biermann K, Mancham S, Hansen BE, Bart Takkenberg R, van Vuuren AJ, Pan Q, Ijzermans JNM, Sleijfer S, ... ... Dong H, et al. Circulating levels of PD-L1 and Galectin-9 are associated with patient survival in surgically treated Hepatocellular Carcinoma independent of their intra-tumoral expression levels. Scientific Reports. 9: 10677. PMID 31337865 DOI: 10.1038/s41598-019-47235-z  0.322
2019 Tu X, Qin B, Zhang Y, Zhang C, Kahila M, Nowsheen S, Yin P, Yuan J, Pei H, Li H, Yu J, Song Z, Zhou Q, Zhao F, Liu J, ... ... Dong H, et al. PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy. Molecular Cell. PMID 31053471 DOI: 10.1016/J.Molcel.2019.04.005  0.434
2019 Duma N, Abdel-Ghani A, Yadav S, Hoversten KP, Reed CT, Sitek AN, Enninga EAL, Paludo J, Aguilera JV, Leventakos K, Lou Y, Kottschade LA, Dong H, Mansfield AS, Manochakian R, et al. Sex Differences in Tolerability to Anti-Programmed Cell Death Protein 1 Therapy in Patients with Metastatic Melanoma and Non-Small Cell Lung Cancer: Are We All Equal? The Oncologist. PMID 31036771 DOI: 10.1634/Theoncologist.2019-0094  0.407
2019 Wu X, Li Y, Liu X, Chen C, Harrington SM, Cao S, Xie T, Pham T, Mansfield AS, Yan Y, Kwon ED, Wang L, Ling K, Dong H. Corrigendum to "Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy" [Heliyon 4 (12) (December 2018) e01039]. Heliyon. 5: e01309. PMID 30937406 DOI: 10.1016/j.heliyon.2019.e01309  0.335
2019 Jalali S, Price-Troska T, Bothun C, Villasboas J, Kim HJ, Yang ZZ, Novak AJ, Dong H, Ansell SM. Reverse signaling via PD-L1 supports malignant cell growth and survival in classical Hodgkin lymphoma. Blood Cancer Journal. 9: 22. PMID 30783096 DOI: 10.1038/S41408-019-0185-9  0.446
2019 Aguilera JV, Erskine CL, Suman VJ, Paludo J, McWilliams RR, Kottschade LA, Yan Y, Dronca RS, Dong H, Markovic S, Block MS. IL-12p40 and MIP3a to predict clinical responses to anti-PD-1 therapy in patients with metastatic melanoma. Journal of Clinical Oncology. 37: 9535-9535. DOI: 10.1200/Jco.2019.37.15_Suppl.9535  0.399
2019 Orme J, Villasboas J, Dong H. Tumor ADAM10/ADAM17-Mediated PD-L1 Loss May Predict Poor Outcomes in Diffuse Large B Cell Lymphoma Blood. 134: 4120-4120. DOI: 10.1182/Blood-2019-124189  0.461
2019 Yan Y, Dong H, Dronca R, Markovic S. Abstract PR11: CX3CR1+CD8+ T-cells are responsible to the clinical benefit of chemoimmunotherapy in metastatic melanoma patients after disease progression on PD-1 blockade Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-Pr11  0.496
2019 Orme JJ, Jazieh K, Harrington S, Ball M, Azam TU, Liu X(, Xie T, Mansfield A, Dronca RS, Dong H. Abstract A210: Tumor-associated ADAM10 and ADAM17 produce soluble PD-L1 (sPD-L1, sB7-H1) and affect downstream tumor immunity – A resistance mechanism to PD-1 checkpoint blockade in melanoma Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A210  0.535
2019 Feng D, Pal K, Mukhopadhyay D, Liu X, Dong H, Huang S, Sinicrope FA. Abstract 705: Tumor intrinsic PD-L1 is mediated byBRAFV600Eand can regulate drug-induced apoptosis in human colon cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-705  0.412
2019 Zhang H, Liu X, Cao S, Chen L, Harrington S, Li Y, Mansfield A, Park S, Yan Y, Dronca R, Dong H. Abstract 4080: Expansion of CX3CR1+ cytotoxic CD8+ T cells provides a rationale for IL-15 in combination cancer therapy with PD-1 antibody Cancer Research. 79: 4080-4080. DOI: 10.1158/1538-7445.Am2019-4080  0.501
2019 Himes B, Peterson T, Tyson J, Lee H, deMooij T, Cumba-Garcia L, Jung M, Gustafson M, Dietz A, Johnson A, Dong H, Maus R, Svetomir M, Lucien-Matteoni F, Yan D, et al. Immu-36. The Role Of Pd-L1 In Glioblastoma-Derived Extracellular Vesicles In The Induction Of Immunosuppressive Monocytes Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.528  0.402
2019 Loeuillard E, Bronk S, Dong H, Rizvi S. 853 – Cholangiocarcinoma (CCA) Derived Extracellular Vesicles Reprogram Hepatic Macrophages to a Pd-L1+ PRO-Tumor Phenotype Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)37262-2  0.415
2019 Mutter RW, Tu X, Qin B, Zhang Y, Zhang C, Kahila MM, Nowsheen S, Yin P, Yuan J, Li H, Yu J, Zhou Q, Zhao F, Liu J, Dong H, et al. PD-L1 is an RNA Binding Protein That Regulates the Expression of DNA Damage Response Genes and Can be Targeted to Sensitize Cancer to Radiation International Journal of Radiation Oncology Biology Physics. 105. DOI: 10.1016/J.Ijrobp.2019.06.559  0.35
2018 Wu X, Li Y, Liu X, Chen C, Harrington SM, Cao S, Xie T, Orzechowski A, Pham T, Mansfield AS, Yan Y, Kwon ED, Wang L, Ling K, Dong H. Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy. Heliyon. 4: e01039. PMID 30603685 DOI: 10.1016/J.Heliyon.2018.E01039  0.496
2018 Jin X, Ding D, Yan Y, Li H, Wang B, Ma L, Ye Z, Ma T, Wu Q, Rodrigues DN, Kohli M, Jimenez R, Wang L, Goodrich DW, de Bono J, ... Dong H, et al. Phosphorylated RB Promotes Cancer Immunity by Inhibiting NF-κB Activation and PD-L1 Expression. Molecular Cell. PMID 30527665 DOI: 10.1016/J.Molcel.2018.10.034  0.49
2018 Liang Y, Tang H, Guo J, Qiu X, Yang Z, Ren Z, Sun Z, Bian Y, Xu L, Xu H, Shen J, Han Y, Dong H, Peng H, Fu YX. Targeting IFNα to tumor by anti-PD-L1 creates feedforward antitumor responses to overcome checkpoint blockade resistance. Nature Communications. 9: 4586. PMID 30389912 DOI: 10.1038/S41467-018-06890-Y  0.512
2018 Evans JD, Morris LK, Zhang H, Cao S, Liu X, Mara KC, Stish BJ, Davis BJ, Mansfield AS, Dronca RS, Iott Cnp MJ, Kwon ED, Foote RL, Olivier KR, Dong H, et al. Prospective Immunophenotyping of CD8 T-cells and Associated Clinical Outcomes of Patients with Oligometastatic Prostate Cancer Treated with Metastasis-Directed SBRT. International Journal of Radiation Oncology, Biology, Physics. PMID 30205124 DOI: 10.1016/J.Ijrobp.2018.09.001  0.39
2018 Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, ... ... Dong H, et al. Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response. Nature. PMID 30089911 DOI: 10.1038/S41586-018-0392-8  0.493
2018 Chakrabarti S, Dong H, Paripati HR, Ross HJ, Yoon HH. First Report of Dramatic Tumor Responses with Ramucirumab and Paclitaxel After Progression on Pembrolizumab in Two Cases of Metastatic Gastroesophageal Adenocarcinoma. The Oncologist. PMID 29674442 DOI: 10.1634/theoncologist.2017-0561  0.358
2018 Yan Y, Cao S, Liu X, Harrington SM, Bindeman WE, Adjei AA, Jang JS, Jen J, Li Y, Chanana P, Mansfield AS, Park SS, Markovic SN, Dronca RS, Dong H. CX3CR1 identifies PD-1 therapy-responsive CD8+ T cells that withstand chemotherapy during cancer chemoimmunotherapy. Jci Insight. 3. PMID 29669928 DOI: 10.1172/Jci.Insight.97828  0.561
2018 Tang H, Liang Y, Anders RA, Taube JM, Qiu X, Mulgaonkar A, Liu X, Harrington SM, Guo J, Xin Y, Xiong Y, Nham K, Silvers W, Hao G, Sun X, ... ... Dong H, et al. PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression. The Journal of Clinical Investigation. PMID 29337303 DOI: 10.1172/Jci96061  0.417
2018 Bhindi B, Lohse CM, Cheville JC, Mason R, Tollefson MK, Harrington S, Dong H, Parker AS, Boorjian SA, Thompson RH, Leibovich BC. Creation of a tissue expression biomarker-augmented prognostic model for patients with metastatic renal cell carcinoma. Journal of Clinical Oncology. 36: 703-703. DOI: 10.1200/Jco.2018.36.6_Suppl.703  0.472
2018 Duma N, Paludo J, Enninga EA, Yadav S, Vera-Aguilera J, Kottschade LA, Dong H, Adjei AA, Dronca RS. Sex differences in tolerability to Anti-PD1 therapy: Are we all equal? Journal of Clinical Oncology. 36: 9547-9547. DOI: 10.1200/Jco.2018.36.15_Suppl.9547  0.361
2018 Wang Y, Sinha S, Dong H, Secreto C, Call T, Parikh SA, Leis JF, Rech K, Feldman AL, Kenderian S, Kay NE, Ansell SM, He R, Ding W. Distinct immune signatures in chronic lymphocytic leukemia (CLL) and Richter’s syndrome (RS). Journal of Clinical Oncology. 36: 7524-7524. DOI: 10.1200/Jco.2018.36.15_Suppl.7524  0.412
2018 Dronca RS, Mansfield A, Liu X, Harrington S, Enninga E, Markovic S, Kottschade L, Mcwilliams R, Block M, Nevala W, Thompson M, Dong H. Abstract A38: Blood-based T cell biomarkers and soluble PD-L1 predict responses and immune-related toxicity to PD-1 blockade in melanoma and lung cancer Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-A38  0.555
2018 Mansfield AS, Peikert T, Smadbeck JB, Udell JB, Kosari F, Murphy SJ, Ren H, Serla VV, Klein JLS, Karagouga G, Harris FR, Sosa C, Johnson SH, Nevala W, Markovic SN, ... ... Dong H, et al. Abstract 5726: Rearrangement-related peptides with neoantigenic potential in malignant pleural mesothelioma Cancer Research. 78: 5726-5726. DOI: 10.1158/1538-7445.Am2018-5726  0.311
2018 Lowerison M, Cepeda M, Liu C, Fedyshyn Y, Joshi V, Shah P, Cheville J, Leibovich B, Boorjian S, Dong H, Leong H. PD57-07 RAPID PATIENT DERIVED XENOGRAFTS THAT CONSIDER TUMOR HETEROGENEITY FOR PREDICTION OF CANCER IMMUNOTHERAPY RESPONSES IN METASTATIC RENAL CELL CARCINOMA Journal of Urology. 199. DOI: 10.1016/J.JURO.2018.02.2651  0.346
2018 Duma N, Azzouqa A, Yadav S, Hoversten K, Reed C, Sitek A, Enninga E, Paludo J, Aguilera JV, Lou Y, Molina J, Leventakos K, Kottschade L, Dong H, Mansfield A, et al. P1.01-17 Immune-Related Adverse Events in Patients with Metastatic Non-Small Cell Lung Cancer: Sex Differences and Response to Therapy Journal of Thoracic Oncology. 13. DOI: 10.1016/J.Jtho.2018.08.573  0.326
2018 Evans JD, Morris LK, Dong H, Cao S, Liu X, Mara K, Stish BJ, Davis BJ, Olivier K, Mansfield AS, Dronca RS, Iott MJ, Kwon ED, Foote RL, Park SS. Prospective Immunophenotyping of CD8+ T-cells and Associated Clinical Outcomes of Patients with Oligometastatic Prostate Cancer Treated with Metastasis-Directed Stereotactic Body Radiation Therapy International Journal of Radiation Oncology Biology Physics. 102. DOI: 10.1016/J.Ijrobp.2018.06.351  0.371
2017 Dong H, Yan Y, Dronca RS, Markovic SN. A T cell equation as a conceptual model of T cell responses for maximizing the efficacy of cancer immunotherapy. Soj Immunology. 5: 1-5. PMID 29629436 DOI: 10.15226/2372-0948/5/1/00155  0.302
2017 Pavelko KD, Bell MP, Harrington SM, Dong H. B7-H1 Influences the Accumulation of Virus-Specific Tissue Resident Memory T Cells in the Central Nervous System. Frontiers in Immunology. 8: 1532. PMID 29170671 DOI: 10.3389/fimmu.2017.01532  0.49
2017 Terra SBSP, Mansfield AS, Dong H, Peikert T, Roden AC. Temporal and spatial heterogeneity of programmed cell death 1-Ligand 1 expression in malignant mesothelioma. Oncoimmunology. 6: e1356146. PMID 29147606 DOI: 10.1080/2162402X.2017.1356146  0.43
2017 Lehrke HD, Graham RP, McWilliams RR, Lam-Himlin DM, Smyrk TC, Jenkins S, Dong H, Zhang L. Undifferentiated Pancreatic Carcinomas Display Enrichment for Frequency and Extent of PD-L1 Expression by Tumor Cells. American Journal of Clinical Pathology. PMID 29069274 DOI: 10.1093/Ajcp/Aqx092  0.445
2017 Gibbons Johnson RM, Dong H. Functional Expression of Programmed Death-Ligand 1 (B7-H1) by Immune Cells and Tumor Cells. Frontiers in Immunology. 8: 961. PMID 28848559 DOI: 10.3389/Fimmu.2017.00961  0.563
2017 Zhou G, Sprengers D, Boor PPC, Doukas M, Schutz H, Mancham S, Pedroza-Gonzalez A, Polak WG, de Jonge J, Gaspersz M, Dong H, Thielemans K, Pan Q, IJzermans JNM, Bruno MJ, et al. Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-infiltrating T cells in Hepatocellular Carcinomas. Gastroenterology. PMID 28648905 DOI: 10.1053/J.Gastro.2017.06.017  0.507
2017 Xue J, Chen C, Qi M, Huang Y, Wang L, Gao Y, Dong H, Ling K. Type Iγ phosphatidylinositol phosphate kinase regulates PD-L1 expression by activating NF-κB. Oncotarget. PMID 28465490 DOI: 10.18632/Oncotarget.17123  0.498
2017 Ding W, LaPlant BR, Call TG, Parikh SA, Leis JF, He R, Shanafelt TD, Sinha S, Le-Rademacher J, Feldman AL, Habermann TM, Witzig TE, Wiseman GA, Lin Y, Asmus E, ... ... Dong H, et al. Pembrolizumab in patients with chronic lymphocytic leukemia with Richter's transformation and relapsed CLL. Blood. PMID 28424162 DOI: 10.1182/Blood-2017-02-765685  0.413
2017 Ni X, Song Q, Cassady K, Deng R, Jin H, Zhang M, Dong H, Forman S, Martin PJ, Chen YZ, Wang J, Zeng D. PD-L1 interacts with CD80 to regulate graft-versus-leukemia activity of donor CD8+ T cells. The Journal of Clinical Investigation. PMID 28414296 DOI: 10.1172/Jci91138  0.426
2017 Yan Y, Dronca RS, Liu X, Markovic S, Dong H. Effect of paclitaxel and carboplatin on tumor-reactive T cells and the efficacy of PD-1 blockade. Journal of Clinical Oncology. 35: 65-65. DOI: 10.1200/Jco.2017.35.7_Suppl.65  0.489
2017 Dronca RS, Harrington S, Jegapragasan M, Kottschade LA, Nevala WK, Enninga EA, Markovic S, Dong H. Association of soluble PD-L1 (sPD-L1) with decreased survival in metastatic melanoma. Journal of Clinical Oncology. 35: 4-4. DOI: 10.1200/Jco.2017.35.7_Suppl.4  0.445
2017 Dronca RS, Mansfield AS, Liu X, Harrington S, Enninga EA, Kottschade LA, Koo CW, McWilliams RR, Block MS, Nevala WK, Markovic S, Dong H. Bim and soluble PD-L1 (sPD-L1) as predictive biomarkers of response to anti-PD-1 therapy in patients with melanoma and lung carcinoma. Journal of Clinical Oncology. 35: 11534-11534. DOI: 10.1200/Jco.2017.35.15_Suppl.11534  0.421
2017 Mansfield A, Liu X, Cao S, Bindeman W, Yin P, Till L, Harrington S, Dong H. 1195PCompromised efficacy of PD-L1 blockade therapy in axenic (germ-free) mice with syngeneic tumors Annals of Oncology. 28. DOI: 10.1093/Annonc/Mdx376.058  0.42
2017 Mansfield A, Ren H, Sutor S, Dronca R, Park S, Markovic S, Nevala W, Jen J, Aubry MC, Dong H. OA 13.07 Contraction of T Cell Clonality in Lung Cancer Metastases Journal of Thoracic Oncology. 12. DOI: 10.1016/J.Jtho.2017.09.406  0.35
2016 Sharma V, Dong H, Kwon E, Karnes RJ. Positive Pelvic Lymph Nodes in Prostate Cancer Harbor Immune Suppressor Cells To Impair Tumor-reactive T Cells. European Urology Focus. PMID 28753790 DOI: 10.1016/j.euf.2016.09.003  0.459
2016 Liu X, Wu X, Cao S, Harrington SM, Yin P, Mansfield AS, Dong H. B7-H1 antibodies lose antitumor activity due to activation of p38 MAPK that leads to apoptosis of tumor-reactive CD8(+) T cells. Scientific Reports. 6: 36722. PMID 27824138 DOI: 10.1038/Srep36722  0.576
2016 Dronca RS, Mansfield AS, Park SS, Dong H. BCL-2-interacting mediator of cell death (Bim) is a novel biomarker for response to anti-PD-1 therapy in patients with advanced melanoma. Immunotherapy. PMID 27784186 DOI: 10.2217/Imt-2016-0100  0.424
2016 Yin P, Liu X, Mansfield AS, Harrington SM, Li Y, Yan Y, Dong H. CpG-induced antitumor immunity requires IL-12 in expansion of effector cells and down-regulation of PD-1. Oncotarget. PMID 27602959 DOI: 10.18632/Oncotarget.11833  0.504
2016 Dronca RS, Liu X, Harrington SM, Chen L, Cao S, Kottschade LA, McWilliams RR, Block MS, Nevala WK, Thompson MA, Mansfield AS, Park SS, Markovic SN, Dong H. T cell Bim levels reflect responses to anti-PD-1 cancer therapy. Jci Insight. 1. PMID 27182556 DOI: 10.1172/Jci.Insight.86014  0.533
2016 Mansfield AS, Dong H. Implications of programmed cell death 1 ligand 1 heterogeneity in the selection of patients with non-small cell lung cancer to receive immunotherapy. Clinical Pharmacology and Therapeutics. PMID 26916808 DOI: 10.1002/Cpt.360  0.453
2016 Dong H, Karnes J. Regional lymph nodes involved by prostate cancer harbor immune suppressor cells that impair the function of tumor-reactive T cells. Journal of Clinical Oncology. 34. DOI: 10.1200/Jco.2016.34.15_Suppl.E16551  0.373
2016 Ding W, Le-Rademacher J, Call TG, Parikh SA, Leis JF, Shanafelt TD, He R, Habermann TM, Lin Y, Laplant BR, Feldman AL, Witzig TE, Chanan-Khan AA, Asmus E, Van Dyke DL, ... ... Dong H, et al. PD-1 Blockade with Pembrolizumab in Relapsed CLL Including Richter's Transformation: An Updated Report from a Phase 2 Trial (MC1485) Blood. 128: 4392-4392. DOI: 10.1182/Blood.V128.22.4392.4392  0.369
2016 Cao S, Liu X, Wu X, Mansfield A, Dong H. Abstract A131: B7-H1 identifies tumor-reactive effector CD8 T cells susceptible of deletion by agonist PD-L1 antibodies Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A131  0.615
2016 Enninga EA, Nevala W, Creedon D, Flotte T, Dong H, Markovic S. Shared immunoregulatory properties of galectin-9 and PD-L1 in pregnant women and patients with stage IV melanoma Placenta. 45: 86-87. DOI: 10.1016/J.Placenta.2016.06.090  0.359
2015 Karyampudi L, Lamichhane P, Krempski J, Kalli KR, Behrens MD, Vargas DM, Hartmann LC, Janco JM, Dong H, Hedin KE, Dietz AB, Goode EL, Knutson KL. PD-1 blunts the function of ovarian tumor-infiltrating dendritic cells by inactivating NF-KappaB. Cancer Research. PMID 26567141 DOI: 10.1158/0008-5472.Can-15-0748  0.43
2015 Park SS, Dong H, Liu X, Harrington SM, Krco CJ, Grams MP, Mansfield AS, Furutani KM, Olivier KR, Kwon ED. PD-1 Restrains Radiotherapy-Induced Abscopal Effect. Cancer Immunology Research. 3: 610-9. PMID 25701325 DOI: 10.1158/2326-6066.Cir-14-0138  0.478
2015 Dronca RS, Dong H. A gender factor in shaping T-cell immunity to melanoma. Frontiers in Oncology. 5: 8. PMID 25699234 DOI: 10.3389/Fonc.2015.00008  0.54
2015 Dronca RS, Markovic S, Kottschade LA, McWilliams RR, Block MS, Nevala WK, Thompson MA, Dong H. Bim as a predictive T-cell biomarker for response to anti-PD-1 therapy in metastatic melanoma (MM). Journal of Clinical Oncology. 33: 9013-9013. DOI: 10.1200/Jco.2015.33.15_Suppl.9013  0.516
2015 Dronca R, Liu X, Lisa K, Mcwilliams R, Markovic S, Dong H. Bim and PD-1 identify effector CD8 T cells responsive to anti-PD-1 therapy in metastatic melanoma patients Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P298  0.58
2015 Ding W, Dong H, Call TG, Shanafelt TD, Parikh SA, Leis JF, Laplant BR, He R, Witzig TE, Lin Y, Chanan-Khan A, Bowen DA, Conte M, Habermann TM, Viswanatha D, et al. PD-1 Blockade with Pembrolizumab (MK-3475) in Relapsed/Refractory CLL Including Richter Transformation: An Early Efficacy Report from a Phase 2 Trial (MC1485) Blood. 126: 834-834. DOI: 10.1182/Blood.V126.23.834.834  0.421
2015 Park SS, Dong H, Harrington S, Grams M, Mansfield AS, Furutani KM, Olivier K, Kwon ED. CD11ahighCD8+ T Cell Phenotype Identifies Tumor Specific Effector Cells Whose Frequency and Function Are Enhanced by RT International Journal of Radiation Oncology Biology Physics. 93. DOI: 10.1016/J.Ijrobp.2015.07.230  0.426
2014 Mansfield AS, Roden AC, Peikert T, Sheinin YM, Harrington SM, Krco CJ, Dong H, Kwon ED. B7-H1 expression in malignant pleural mesothelioma is associated with sarcomatoid histology and poor prognosis. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 1036-40. PMID 24926549 DOI: 10.1097/Jto.0000000000000177  0.449
2014 Gibbons RM, Liu X, Harrington SM, Krco CJ, Kwon ED, Dong H. B7-H1 signaling is integrated during CD8(+) T cell priming and restrains effector differentiation. Cancer Immunology, Immunotherapy : Cii. 63: 859-67. PMID 24893858 DOI: 10.1007/s00262-014-1563-6  0.478
2014 Dong H, Zhao W, Krco CJ, Markovic S, Mansfield AS, Olivier KR, Park SS, Kwon ED. A novel method for identifying downstream signals in tumor-reactive T cells following PD-1 engagement and monitoring endogenous tumor immunity and immunotherapy. Journal of Clinical Oncology. 32: 3049-3049. DOI: 10.1200/Jco.2014.32.15_Suppl.3049  0.548
2014 Orzechowski A, Dong H. Abstract 5026: B7-H1 confers tumor chemoresistance by regulating MAPK/ERK activation Cancer Research. 74: 5026-5026. DOI: 10.1158/1538-7445.Am2014-5026  0.489
2014 Zhao W, Dong H. Abstract 2552: T cell apoptosis signaling biomarker of PD-1 engagement in cancer patients Cancer Research. 74: 2552-2552. DOI: 10.1158/1538-7445.Am2014-2552  0.584
2014 Park SS, Dong H, Zhao W, Grams MP, Liu X, Harrington SM, Furutani KM, Krco CJ, Olivier KR, Markovic SN, Kwon ED. PD-1 Blockade Enhances Radiation Therapy-Induced Abscopal Effect International Journal of Radiation Oncology Biology Physics. 90. DOI: 10.1016/J.Ijrobp.2014.05.201  0.361
2013 Liu X, Gibbons RM, Harrington SM, Krco CJ, Markovic SN, Kwon ED, Dong H. Endogenous tumor-reactive CD8(+) T cells are differentiated effector cells expressing high levels of CD11a and PD-1 but are unable to control tumor growth. Oncoimmunology. 2: e23972. PMID 23894697 DOI: 10.4161/Onci.23972  0.564
2013 Tamura H, Ishibashi M, Yamashita T, Tanosaki S, Okuyama N, Kondo A, Hyodo H, Shinya E, Takahashi H, Dong H, Tamada K, Chen L, Dan K, Ogata K. Marrow stromal cells induce B7-H1 expression on myeloma cells, generating aggressive characteristics in multiple myeloma. Leukemia. 27: 464-72. PMID 22828443 DOI: 10.1038/Leu.2012.213  0.512
2013 Dong H, Markovic S, Krco CJ, Kwon ED. A novel method to identify and monitor endogenous tumor-reactive T cells by high expression of CD11a (LFA-1) and PD-1 (CD279) as immunologic readout for evaluating the efficacy of PD-1 blockade. Journal of Clinical Oncology. 31: 3037-3037. DOI: 10.1200/Jco.2013.31.15_Suppl.3037  0.571
2012 Gibbons RM, Liu X, Pulko V, Harrington SM, Krco CJ, Kwon ED, Dong H. B7-H1 limits the entry of effector CD8(+) T cells to the memory pool by upregulating Bim. Oncoimmunology. 1: 1061-1073. PMID 23170254 DOI: 10.4161/Onci.20850  0.795
2012 Frigola X, Inman BA, Krco CJ, Liu X, Harrington SM, Bulur PA, Dietz AB, Dong H, Kwon ED. Soluble B7-H1: differences in production between dendritic cells and T cells. Immunology Letters. 142: 78-82. PMID 22138406 DOI: 10.1016/J.Imlet.2011.11.001  0.547
2011 Pulko V, Harris KJ, Liu X, Gibbons RM, Harrington SM, Krco CJ, Kwon ED, Dong H. B7-h1 expressed by activated CD8 T cells is essential for their survival. Journal of Immunology (Baltimore, Md. : 1950). 187: 5606-14. PMID 22025548 DOI: 10.4049/Jimmunol.1003976  0.783
2011 Krempski J, Karyampudi L, Behrens MD, Erskine CL, Hartmann L, Dong H, Goode EL, Kalli KR, Knutson KL. Tumor-infiltrating programmed death receptor-1+ dendritic cells mediate immune suppression in ovarian cancer. Journal of Immunology (Baltimore, Md. : 1950). 186: 6905-13. PMID 21551365 DOI: 10.4049/Jimmunol.1100274  0.601
2011 Frigola X, Inman BA, Lohse CM, Krco CJ, Cheville JC, Thompson RH, Leibovich B, Blute ML, Dong H, Kwon ED. Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 1915-23. PMID 21355078 DOI: 10.1158/1078-0432.Ccr-10-0250  0.442
2010 Archibald DJ, Neff BA, Voss SG, Splinter PL, Driscoll CL, Link MJ, Dong H, Kwon ED. B7-H1 expression in vestibular schwannomas. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 31: 991-7. PMID 20601920 DOI: 10.1097/Mao.0B013E3181E40E4F  0.395
2010 Nguyen LT, Ciric B, Ure DR, Zhou B, Tamada K, Tseng SY, Shin T, Chen L, Dong H, Kyle RA, Rodriguez M, Pease LR. Retraction: Naturally occurring human IgM antibody that binds B7-DC and potentiates T cell stimulation by dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 6552. PMID 20483792 DOI: 10.4049/Jimmunol.1090031  0.392
2010 Mirza N, Duque MA, Dominguez AL, Schrum AG, Dong H, Lustgarten J. B7-H1 expression on old CD8+ T cells negatively regulates the activation of immune responses in aged animals. Journal of Immunology (Baltimore, Md. : 1950). 184: 5466-74. PMID 20375308 DOI: 10.4049/Jimmunol.0903561  0.455
2009 Pulko V, Liu X, Krco CJ, Harris KJ, Frigola X, Kwon ED, Dong H. TLR3-stimulated dendritic cells up-regulate B7-H1 expression and influence the magnitude of CD8 T cell responses to tumor vaccination. Journal of Immunology (Baltimore, Md. : 1950). 183: 3634-41. PMID 19710456 DOI: 10.4049/Jimmunol.0900974  0.775
2009 Wilcox RA, Feldman AL, Wada DA, Yang ZZ, Comfere NI, Dong H, Kwon ED, Novak AJ, Markovic SN, Pittelkow MR, Witzig TE, Ansell SM. B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders. Blood. 114: 2149-58. PMID 19597183 DOI: 10.1182/Blood-2009-04-216671  0.604
2009 Gong AY, Zhou R, Hu G, Li X, Splinter PL, O'Hara SP, LaRusso NF, Soukup GA, Dong H, Chen XM. MicroRNA-513 regulates B7-H1 translation and is involved in IFN-gamma-induced B7-H1 expression in cholangiocytes. Journal of Immunology (Baltimore, Md. : 1950). 182: 1325-33. PMID 19155478 DOI: 10.4049/Jimmunol.182.3.1325  0.414
2009 Archibald DJ, Driscoll CLW, Neff BA, Voss SG, Link MJ, Dong H, Kwon ED. B7 homolog 1 expression in vestibular schwannomas Otolaryngology-Head and Neck Surgery. 141. DOI: 10.1016/J.Otohns.2009.06.227  0.345
2008 Crispen PL, Sheinin Y, Roth TJ, Lohse CM, Kuntz SM, Frigola X, Thompson RH, Boorjian SA, Dong H, Leibovich BC, Blute ML, Kwon ED. Tumor cell and tumor vasculature expression of B7-H3 predict survival in clear cell renal cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 5150-7. PMID 18694993 DOI: 10.1158/1078-0432.Ccr-08-0536  0.489
2008 Dong H, Fulko V, Harris K, Frigola X, Liu X. The reverse signals of costimulatory molecule B7-H1 negatively regulate memory CD8 T cell function in tumor immunity The Faseb Journal. 22: 523-523. DOI: 10.1096/Fasebj.22.2_Supplement.523  0.513
2008 Tollefson MK, Leibovich BC, Cheville JC, Baro XF, Dong H, Kwon ED. CD-4+ CD-25hi REGULATORY T-CELLS IN THE REGIONAL LYMPH NODES OF PATIENTS WITH UROTHELIAL CARCINOMA The Journal of Urology. 179: 314-314. DOI: 10.1016/S0022-5347(08)60919-2  0.385
2007 Webster WS, Thompson RH, Harris KJ, Frigola X, Kuntz S, Inman BA, Dong H. Targeting molecular and cellular inhibitory mechanisms for improvement of antitumor memory responses reactivated by tumor cell vaccine. Journal of Immunology (Baltimore, Md. : 1950). 179: 2860-9. PMID 17709500 DOI: 10.4049/jimmunol.179.5.2860  0.409
2007 Siddiqui SA, Frigola X, Bonne-Annee S, Mercader M, Kuntz SM, Krambeck AE, Sengupta S, Dong H, Cheville JC, Lohse CM, Krco CJ, Webster WS, Leibovich BC, Blute ML, Knutson KL, et al. Tumor-infiltrating Foxp3-CD4+CD25+ T cells predict poor survival in renal cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2075-81. PMID 17404089 DOI: 10.1158/1078-0432.Ccr-06-2139  0.477
2007 Thompson RH, Dong H, Lohse CM, Leibovich BC, Blute ML, Cheville JC, Kwon ED. PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 1757-61. PMID 17363529 DOI: 10.1158/1078-0432.Ccr-06-2599  0.551
2007 Krambeck AE, Dong H, Thompson RH, Kuntz SM, Lohse CM, Leibovich BC, Blute ML, Sebo TJ, Cheville JC, Parker AS, Kwon ED. Survivin and b7-h1 are collaborative predictors of survival and represent potential therapeutic targets for patients with renal cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 1749-56. PMID 17363528 DOI: 10.1158/1078-0432.CCR-06-2129  0.479
2007 Inman BA, Sebo TJ, Frigola X, Dong H, Bergstralh EJ, Frank I, Fradet Y, Lacombe L, Kwon ED. PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata: associations with localized stage progression. Cancer. 109: 1499-505. PMID 17340590 DOI: 10.1016/S0022-5347(18)31107-8  0.514
2007 Inman BA, Frigola X, Dong H, Kwon ED. Costimulation, coinhibition and cancer. Current Cancer Drug Targets. 7: 15-30. PMID 17305475 DOI: 10.2174/156800907780006878  0.492
2007 Thompson RH, Dong H, Kwon ED. Implications of B7-H1 expression in clear cell carcinoma of the kidney for prognostication and therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 709s-715s. PMID 17255298 DOI: 10.1158/1078-0432.Ccr-06-1868  0.541
2007 Tollefson MK, Leibovich BC, Cheville JC, Dong H, Kwon ED. MP-04.07: CD-4+ CD-25+ regulatory T-cells in the tumor draining lymph nodes of patients with urothelial carcinoma Urology. 70: 60. DOI: 10.1016/J.Urology.2007.06.235  0.418
2006 Zhang X, Dong H, Lin W, Voss S, Hinkley L, Westergren M, Tian G, Berry D, Lewellen D, Vile RG, Chen L, Farber DL, Strome SE. Human bone marrow: a reservoir for "enhanced effector memory" CD8+ T cells with potent recall function. Journal of Immunology (Baltimore, Md. : 1950). 177: 6730-7. PMID 17082586 DOI: 10.4049/Jimmunol.177.10.6730  0.433
2006 Dong H, Chen X. Immunoregulatory role of B7-H1 in chronicity of inflammatory responses. Cellular & Molecular Immunology. 3: 179-87. PMID 16893498  0.382
2006 Krambeck AE, Thompson RH, Dong H, Lohse CM, Park ES, Kuntz SM, Leibovich BC, Blute ML, Cheville JC, Kwon ED. B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival. Proceedings of the National Academy of Sciences of the United States of America. 103: 10391-6. PMID 16798883 DOI: 10.1073/Pnas.0600937103  0.495
2006 Webster WS, Lohse CM, Thompson RH, Dong H, Frigola X, Dicks DL, Sengupta S, Frank I, Leibovich BC, Blute ML, Cheville JC, Kwon ED. Mononuclear cell infiltration in clear-cell renal cell carcinoma independently predicts patient survival. Cancer. 107: 46-53. PMID 16708355 DOI: 10.1002/Cncr.21951  0.378
2006 Thompson RH, Kuntz SM, Leibovich BC, Dong H, Lohse CM, Webster WS, Sengupta S, Frank I, Parker AS, Zincke H, Blute ML, Sebo TJ, Cheville JC, Kwon ED. Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up. Cancer Research. 66: 3381-5. PMID 16585157 DOI: 10.1158/0008-5472.Can-05-4303  0.493
2006 Webster WS, Lohse CM, Thompson RH, Dong H, Frigola X, Dicks D, Sengupta S, Frank I, Leibovich BC, Blute ML, Cheville JC, Kwon ED. 746: Mononuclear Cell Infiltration in Clear Cell Renal Cell Carcinoma Independently Predicts Patient Survival The Journal of Urology. 175: 242-243. DOI: 10.1016/S0022-5347(18)32982-3  0.341
2006 Webster WS, Dong H, Thompson RH, Sengupta S, Lohse CM, Leibovich BC, Blute ML, Kwon ED. 399: Complete Tumor Regression of Established Murine Renal Cell Carcinoma Following CD4+ T Cell Depletion and B7-H1 Blockade The Journal of Urology. 175: 130-130. DOI: 10.1016/S0022-5347(18)32655-7  0.524
2006 Krambeck AE, Parks E, Lohse CM, Cheville JC, Dong H, Leibovich BC, Blute ML, Kwon ED. 387: The Immunomodulatory Protein B7-H4 Expression in Renal Cell Carcinoma Patients: A Strong Predictor of Cancer Progression and Survival The Journal of Urology. 175: 127-127. DOI: 10.1016/S0022-5347(18)32643-0  0.403
2006 Thompson RH, Leibovich BC, Dong H, Lohse CM, Webster WS, Zincke H, Blute ML, Sebo TJ, Cheville JC, Kwon ED. 386: Tumor B7-H1 is Associated with Poor Prognosis in Renal Cell Carcinoma Patients with Long Term Follow-Up The Journal of Urology. 175: 126-126. DOI: 10.1016/S0022-5347(18)32642-9  0.409
2006 Thompson RH, Dong H, Lohse CM, Cheville JC, Kwon ED. 385: PD-1 Expression by Tumor Infiltrating Lymphocytes is Associated with Poor Prognosis in Renal Cell Carcinoma Patients The Journal of Urology. 175: 126-126. DOI: 10.1016/S0022-5347(18)32641-7  0.468
2005 Thompson RH, Gillett MD, Cheville JC, Lohse CM, Dong H, Webster WS, Chen L, Zincke H, Blute ML, Leibovich BC, Kwon ED. Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma. Cancer. 104: 2084-91. PMID 16208700 DOI: 10.1002/cncr.21470  0.38
2005 Thompson RH, Webster WS, Cheville JC, Lohse CM, Dong H, Leibovich BC, Kuntz SM, Sengupta S, Kwon ED, Blute ML. B7-H1 glycoprotein blockade: a novel strategy to enhance immunotherapy in patients with renal cell carcinoma. Urology. 66: 10-4. PMID 16194701 DOI: 10.1016/J.Urology.2005.06.010  0.493
2005 Tamura H, Dan K, Tamada K, Nakamura K, Shioi Y, Hyodo H, Wang SD, Dong H, Chen L, Ogata K. Expression of functional B7-H2 and B7.2 costimulatory molecules and their prognostic implications in de novo acute myeloid leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 5708-17. PMID 16115907 DOI: 10.1158/1078-0432.Ccr-04-2672  0.455
2005 Hirano F, Kaneko K, Tamura H, Dong H, Wang S, Ichikawa M, Rietz C, Flies DB, Lau JS, Zhu G, Tamada K, Chen L. Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity. Cancer Research. 65: 1089-96. PMID 15705911  0.478
2005 Thompson RH, Gillett MD, Cheville JC, Lohse CM, Dong H, Webster WS, Krejci KG, Lobo JR, Sengupta S, Chen L, Zincke H, Blute ML, Strome SE, Leibovich BC, Kwon ED. 618: Costimulatory B7-H1 In Renal Cell Carcinoma Patients: Indicator of Tumor Aggressiveness and Potential Therapeutic Target The Journal of Urology. 173: 169-169. DOI: 10.1016/S0022-5347(18)34858-4  0.425
2004 Thompson RH, Gillett MD, Cheville JC, Lohse CM, Dong H, Webster WS, Krejci KG, Lobo JR, Sengupta S, Chen L, Zincke H, Blute ML, Strome SE, Leibovich BC, Kwon ED. Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target. Proceedings of the National Academy of Sciences of the United States of America. 101: 17174-9. PMID 15569934 DOI: 10.1073/pnas.0406351101  0.439
2004 Roden AC, Moser MT, Tri SD, Mercader M, Kuntz SM, Dong H, Hurwitz AA, McKean DJ, Celis E, Leibovich BC, Allison JP, Kwon ED. Augmentation of T cell levels and responses induced by androgen deprivation. Journal of Immunology (Baltimore, Md. : 1950). 173: 6098-108. PMID 15528346 DOI: 10.4049/Jimmunol.173.10.6098  0.431
2004 Luo L, Chapoval AI, Flies DB, Zhu G, Hirano F, Wang S, Lau JS, Dong H, Tamada K, Flies AS, Liu Y, Chen L. B7-H3 enhances tumor immunity in vivo by costimulating rapid clonal expansion of antigen-specific CD8+ cytolytic T cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 5445-50. PMID 15494491 DOI: 10.4049/Jimmunol.173.9.5445  0.561
2004 Dong H, Zhu G, Tamada K, Flies DB, van Deursen JM, Chen L. B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes. Immunity. 20: 327-36. PMID 15030776 DOI: 10.1016/S1074-7613(04)00050-0  0.464
2003 Tamura H, Ogata K, Dong H, Chen L. Immunology of B7-H1 and its roles in human diseases. International Journal of Hematology. 78: 321-8. PMID 14686489 DOI: 10.1007/Bf02983556  0.486
2003 Strome SE, Dong H, Tamura H, Voss SG, Flies DB, Tamada K, Salomao D, Cheville J, Hirano F, Lin W, Kasperbauer JL, Ballman KV, Chen L. B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma. Cancer Research. 63: 6501-5. PMID 14559843  0.438
2003 Dong H, Chen L. B7-H1 pathway and its role in the evasion of tumor immunity. Journal of Molecular Medicine (Berlin, Germany). 81: 281-7. PMID 12721664 DOI: 10.1007/S00109-003-0430-2  0.558
2003 Wang S, Bajorath J, Flies DB, Dong H, Honjo T, Chen L. Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. The Journal of Experimental Medicine. 197: 1083-91. PMID 12719480 DOI: 10.1084/Jem.20021752  0.51
2003 Curiel TJ, Wei S, Dong H, Alvarez X, Cheng P, Mottram P, Krzysiek R, Knutson KL, Daniel B, Zimmermann MC, David O, Burow M, Gordon A, Dhurandhar N, Myers L, et al. Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nature Medicine. 9: 562-7. PMID 12704383 DOI: 10.1038/Nm863  0.536
2003 Dong H, Strome SE, Matteson EL, Moder KG, Flies DB, Zhu G, Tamura H, Driscoll CLW, Chen L. Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritis Journal of Clinical Investigation. 111: 363-370. PMID 12569162 DOI: 10.1172/Jci16015  0.429
2003 Trabattoni D, Saresella M, Biasin M, Boasso A, Piacentini L, Ferrante P, Dong H, Maserati R, Shearer GM, Chen L, Clerici M. B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression. Blood. 101: 2514-20. PMID 12468426 DOI: 10.1182/Blood-2002-10-3065  0.338
2002 Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB, Roche PC, Lu J, Zhu G, Tamada K, Lennon VA, Celis E, Chen L. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nature Medicine. 8: 793-800. PMID 12091876 DOI: 10.1038/Nm730  0.582
2002 Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB, Roche PC, Lu J, Zhu G, Tamada K, Lennon VA, Celis E, Chen L. Erratum: Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion Nature Medicine. 8: 1039-1039. DOI: 10.1038/nm0902-1039c  0.422
2001 Tamura H, Dong H, Zhu G, Sica GL, Flies DB, Tamada K, Chen L. B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function. Blood. 97: 1809-16. PMID 11238124 DOI: 10.1182/Blood.V97.6.1809  0.541
2001 Chapoval AI, Ni J, Lau JS, Wilcox RA, Flies DB, Liu D, Dong H, Sica GL, Zhu G, Tamada K, Chen L. B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. Nature Immunology. 2: 269-74. PMID 11224528 DOI: 10.1038/85339  0.558
2000 Wang S, Zhu G, Chapoval AI, Dong H, Tamada K, Ni J, Chen L. Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS Blood. 96: 2808-2813. DOI: 10.1182/Blood.V96.8.2808  0.498
1999 Dong H, Zhu G, Tamada K, Chen L. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nature Medicine. 5: 1365-9. PMID 10581077 DOI: 10.1038/70932  0.501
1994 Kimoto Y, Lee-Miyamoto M, Dong H, Takai S, Taguchi T. Treatment of malignant diseases using lectin-dependent lymphokine-activated killer cell-mediated cytotoxicity Japanese Journal of Clinical Immunology. 17: 188-198. DOI: 10.2177/Jsci.17.188  0.336
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