| Year |
Citation |
Score |
| 2017 |
Zhao HF, Abraham A, Kim YS, Wang YD, Pestina T, Zhan J, Humphries K, Nienhuis AW, Persons DA. Lentiviral Transfer of γ-Globin with Fusion Gene NUP98-HOXA10HD Expands Hematopoietic Stem Cells and Ameliorates Murine β-Thalassemia. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28190779 DOI: 10.1016/j.ymthe.2017.01.019 |
0.56 |
|
| 2016 |
Villamizar O, Chambers CB, Mo YY, Torry DS, Hofstrand R, Riberdy JM, Persons DA, Wilber A. Data in support of transcriptional regulation and function of Fas-antisense long noncoding RNA during human erythropoiesis. Data in Brief. 7: 1288-95. PMID 27141526 DOI: 10.1016/J.Dib.2016.03.106 |
0.357 |
|
| 2016 |
Villamizar O, Chambers CB, Mo YY, Torry DS, Hofstrand R, Riberdy JM, Persons DA, Wilber A. Fas-antisense long noncoding RNA is differentially expressed during maturation of human erythrocytes and confers resistance to Fas-mediated cell death. Blood Cells, Molecules & Diseases. 58: 57-66. PMID 27067490 DOI: 10.1016/J.Bcmd.2016.03.002 |
0.444 |
|
| 2016 |
Abraham A, Kim YS, Zhao H, Humphries K, Persons DA. Increased Engraftment of Human Short Term Repopulating Hematopoietic Cells in NOD/SCID/IL2rγnull Mice by Lentiviral Expression of NUP98-HOXA10HD. Plos One. 11: e0147059. PMID 26761813 DOI: 10.1371/journal.pone.0147059 |
0.465 |
|
| 2015 |
Pestina TI, Hargrove PW, Zhao H, Mead PE, Smeltzer MP, Weiss MJ, Wilber A, Persons DA. Amelioration of murine sickle cell disease by nonablative conditioning and γ-globin gene-corrected bone marrow cells. Molecular Therapy. Methods & Clinical Development. 2: 15045. PMID 26665131 DOI: 10.1038/Mtm.2015.45 |
0.581 |
|
| 2015 |
Nandakumar SK, Johnson K, Throm SL, Pestina TI, Neale G, Persons DA. Low-level GATA2 overexpression promotes myeloid progenitor self-renewal and blocks lymphoid differentiation in mice. Experimental Hematology. 43: 565-577.e10. PMID 25907033 DOI: 10.1016/J.Exphem.2015.04.002 |
0.578 |
|
| 2015 |
Urbinati F, Hargrove PW, Geiger S, Romero Z, Wherley J, Kaufman ML, Hollis RP, Chambers CB, Persons DA, Kohn DB, Wilber A. Potentially therapeutic levels of anti-sickling globin gene expression following lentivirus-mediated gene transfer in sickle cell disease bone marrow CD34+ cells. Experimental Hematology. 43: 346-51. PMID 25681747 DOI: 10.1016/J.Exphem.2015.01.009 |
0.573 |
|
| 2014 |
Nasimuzzaman M, Kim YS, Wang YD, Persons DA. High-titer foamy virus vector transduction and integration sites of human CD34(+) cell-derived SCID-repopulating cells. Molecular Therapy. Methods & Clinical Development. 1: 14020. PMID 26015964 DOI: 10.1038/mtm.2014.20 |
0.436 |
|
| 2013 |
Holmfeldt P, Pardieck J, Saulsberry AC, Nandakumar SK, Finkelstein D, Gray JT, Persons DA, McKinney-Freeman S. Nfix is a novel regulator of murine hematopoietic stem and progenitor cell survival. Blood. 122: 2987-96. PMID 24041575 DOI: 10.1182/Blood-2013-04-493973 |
0.581 |
|
| 2012 |
Uchida N, Hargrove PW, Lap CJ, Evans ME, Phang O, Bonifacino AC, Krouse AE, Metzger ME, Nguyen AD, Hsieh MM, Wolfsberg TG, Donahue RE, Persons DA, Tisdale JF. High-efficiency transduction of rhesus hematopoietic repopulating cells by a modified HIV1-based lentiviral vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1882-92. PMID 22871664 DOI: 10.1038/mt.2012.159 |
0.321 |
|
| 2012 |
Nasimuzzaman M, Persons DA. Cell Membrane-associated heparan sulfate is a receptor for prototype foamy virus in human, monkey, and rodent cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1158-66. PMID 22434139 DOI: 10.1038/mt.2012.41 |
0.378 |
|
| 2011 |
Kasow KA, Morales-Tirado VM, Wichlan D, Shurtleff SA, Abraham A, Persons DA, Riberdy JM. Therapeutic in vivo selection of thymic-derived natural T regulatory cells following non-myeloablative hematopoietic stem cell transplant for IPEX. Clinical Immunology (Orlando, Fla.). 141: 169-76. PMID 21865090 DOI: 10.1016/J.Clim.2011.07.005 |
0.463 |
|
| 2011 |
Wilber A, Nienhuis AW, Persons DA. Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities. Blood. 117: 3945-53. PMID 21321359 DOI: 10.1182/Blood-2010-11-316893 |
0.315 |
|
| 2011 |
Hunter MJ, Zhao H, Tuschong LM, Bauer TR, Burkholder TH, Persons DA, Hickstein DD. Gene therapy for canine leukocyte adhesion deficiency with lentiviral vectors using the murine stem cell virus and human phosphoglycerate kinase promoters. Human Gene Therapy. 22: 689-96. PMID 21275758 DOI: 10.1089/hum.2010.130 |
0.397 |
|
| 2011 |
Wilber A, Hargrove PW, Kim YS, Riberdy JM, Sankaran VG, Papanikolaou E, Georgomanoli M, Anagnou NP, Orkin SH, Nienhuis AW, Persons DA. Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer. Blood. 117: 2817-26. PMID 21156846 DOI: 10.1182/Blood-2010-08-300723 |
0.346 |
|
| 2010 |
Persons DA. The challenge of obtaining therapeutic levels of genetically modified hematopoietic stem cells in beta-thalassemia patients. Annals of the New York Academy of Sciences. 1202: 69-74. PMID 20712775 DOI: 10.1111/j.1749-6632.2010.05581.x |
0.4 |
|
| 2010 |
Lebensburger JD, Pestina TI, Ware RE, Boyd KL, Persons DA. Hydroxyurea therapy requires HbF induction for clinical benefit in a sickle cell mouse model. Haematologica. 95: 1599-603. PMID 20378564 DOI: 10.1182/Blood.V114.22.817.817 |
0.43 |
|
| 2010 |
Kim YS, Wielgosz MM, Hargrove P, Kepes S, Gray J, Persons DA, Nienhuis AW. Transduction of human primitive repopulating hematopoietic cells with lentiviral vectors pseudotyped with various envelope proteins. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1310-7. PMID 20372106 DOI: 10.1038/mt.2010.48 |
0.349 |
|
| 2010 |
Wilber A, Tschulena U, Hargrove PW, Kim YS, Persons DA, Barbas CF, Nienhuis AW. A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts. Blood. 115: 3033-41. PMID 20190190 DOI: 10.1182/Blood-2009-08-240556 |
0.427 |
|
| 2009 |
Pestina TI, Hargrove PW, Jay D, Gray JT, Boyd KM, Persons DA. Correction of Murine Sickle Cell Disease Using γ-Globin Lentiviral Vectors to Mediate High-level Expression of Fetal Hemoglobin. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 245-252. PMID 28192693 DOI: 10.1038/mt.2008.259 |
0.478 |
|
| 2009 |
Persons DA. Hematopoietic stem cell gene transfer for the treatment of hemoglobin disorders. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 690-7. PMID 20008255 DOI: 10.1182/asheducation-2009.1.690 |
0.404 |
|
| 2009 |
Larochelle A, Choi U, Shou Y, Naumann N, Loktionova NA, Clevenger JR, Krouse A, Metzger M, Donahue RE, Kang E, Stewart C, Persons D, Malech HL, Dunbar CE, Sorrentino BP. In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene. The Journal of Clinical Investigation. 119: 1952-63. PMID 19509470 DOI: 10.1172/Jci37506 |
0.543 |
|
| 2009 |
Zhao H, Pestina TI, Nasimuzzaman M, Mehta P, Hargrove PW, Persons DA. Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene. Blood. 113: 5747-56. PMID 19365082 DOI: 10.1182/blood-2008-10-186684 |
0.525 |
|
| 2009 |
Soulas C, Donahue RE, Dunbar CE, Persons DA, Alvarez X, Williams KC. Genetically modified CD34+ hematopoietic stem cells contribute to turnover of brain perivascular macrophages in long-term repopulated primates. The American Journal of Pathology. 174: 1808-17. PMID 19349370 DOI: 10.2353/ajpath.2009.081010 |
0.338 |
|
| 2009 |
Kim YJ, Kim YS, Larochelle A, Renaud G, Wolfsberg TG, Adler R, Donahue RE, Hematti P, Hong BK, Roayaei J, Akagi K, Riberdy JM, Nienhuis AW, Dunbar CE, Persons DA. Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells. Blood. 113: 5434-43. PMID 19339698 DOI: 10.1182/blood-2008-10-185199 |
0.49 |
|
| 2009 |
Pestina TI, Hargrove PW, Jay D, Gray JT, Boyd KM, Persons DA. Correction of murine sickle cell disease using γ-globin lentiviral vectors to mediate high-level expression of fetal hemoglobin Molecular Therapy. 17: 245-252. PMID 19050697 DOI: 10.1038/mt.2008.259 |
0.474 |
|
| 2009 |
Uchida N, Hargrove PW, Washington K, Lap CJ, Hsieh MM, Bonifacino AC, Price SD, Krouse AE, Metzger ME, Donahue RE, Persons D, Tisdale JF. A Modified HIV1-Based Lentiviral Vector Can Transduce Rhesus Hematopoietic Repopulating Cells as Efficiently as An SIV Vector in An Autologous Transplantation Model. Blood. 114: 692-692. DOI: 10.1182/Blood.V114.22.692.692 |
0.476 |
|
| 2009 |
Harrow FJ, Cline AP, Seidel NE, Persons D, Gallagher PG, Bodine DM. A Modified ANK-1 Promoter Directs Uniform, Copy Number Dependent Gamma Globin Gene Expression at Therapeutic Levels of a in a Lentivirus Vector. Blood. 114: 3565-3565. DOI: 10.1182/Blood.V114.22.3565.3565 |
0.458 |
|
| 2009 |
Hargrove PW, Sang KY, Persons D. High Levels of Multilineage Hematopoietic Cell Gene Marking Following Lentiviral Vector Transduction and Transplantation of Steady-State Bone Marrow CD34+ cells in a Non-Human Primate Model. Blood. 114: 2464-2464. DOI: 10.1182/Blood.V114.22.2464.2464 |
0.593 |
|
| 2008 |
Hargrove PW, Kepes S, Hanawa H, Obenauer JC, Pei D, Cheng C, Gray JT, Neale G, Persons DA. Globin Lentiviral Vector Insertions Can Perturb the Expression of Endogenous Genes in β-thalassemic Hematopoietic Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 525-533. PMID 28178501 DOI: 10.1038/sj.mt.6300394 |
0.368 |
|
| 2008 |
Lebensburger J, Persons DA. Progress toward safe and effective gene therapy for beta-thalassemia and sickle cell disease. Current Opinion in Drug Discovery & Development. 11: 225-32. PMID 18283610 |
0.421 |
|
| 2008 |
Hargrove PW, Kepes S, Hanawa H, Obenauer JC, Pei D, Cheng C, Gray JT, Neale G, Persons DA. Globin lentiviral vector insertions can perturb the expression of endogenous genes in beta-thalassemic hematopoietic cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 525-33. PMID 18195719 DOI: 10.1038/Sj.Mt.6300394 |
0.378 |
|
| 2008 |
Ryu BY, Evans-Galea MV, Gray JT, Bodine DM, Persons DA, Nienhuis AW. An experimental system for the evaluation of retroviral vector design to diminish the risk for proto-oncogene activation. Blood. 111: 1866-75. PMID 17991809 DOI: 10.1182/Blood-2007-04-085506 |
0.313 |
|
| 2008 |
Hargrove PW, Pestina TI, Kim YS, Gray J, Boyd K, Persons D. Evaluation of a γ-Globin Lentiviral Vector in Sickle Cell Mice and Pigtail Macaques Blood. 112: 818-818. DOI: 10.1182/Blood.V112.11.818.818 |
0.546 |
|
| 2007 |
Ryu BY, Persons DA, Evans-Galea MV, Gray JT, Nienhuis AW. A chromatin insulator blocks interactions between globin regulatory elements and cellular promoters in erythroid cells. Blood Cells, Molecules & Diseases. 39: 221-8. PMID 17601756 DOI: 10.1016/j.bcmd.2007.05.003 |
0.372 |
|
| 2007 |
Miller ML, Gao G, Pestina T, Persons D, Tuomanen E. Hypersusceptibility to invasive pneumococcal infection in experimental sickle cell disease involves platelet-activating factor receptor. The Journal of Infectious Diseases. 195: 581-4. PMID 17230418 DOI: 10.1086/510626 |
0.488 |
|
| 2005 |
Dominici M, Tadjali M, Kepes S, Allay ER, Boyd K, Ney PA, Horwitz E, Persons DA. Transgenic mice with pancellular enhanced green fluorescent protein expression in primitive hematopoietic cells and all blood cell progeny Genesis. 42: 17-22. PMID 15828004 DOI: 10.1002/Gene.20121 |
0.556 |
|
| 2004 |
Hematti P, Hong BK, Ferguson C, Adler R, Hanawa H, Sellers S, Holt IE, Eckfeldt CE, Sharma Y, Schmidt M, von Kalle C, Persons DA, Billings EM, Verfaillie CM, Nienhuis AW, et al. Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells. Plos Biology. 2: e423. PMID 15550989 DOI: 10.1371/Journal.Pbio.0020423 |
0.373 |
|
| 2004 |
Persons DA, Tisdale JF. Gene therapy for the hemoglobin disorders. Seminars in Hematology. 41: 279-86. PMID 15508113 |
0.408 |
|
| 2004 |
Dominici M, Pritchard C, Garlits JE, Hofmann TJ, Persons DA, Horwitz EM. Hematopoietic cells and osteoblasts are derived from a common marrow progenitor after bone marrow transplantation. Proceedings of the National Academy of Sciences of the United States of America. 101: 11761-6. PMID 15282377 DOI: 10.1073/pnas.0404626101 |
0.514 |
|
| 2004 |
Hanawa H, Hematti P, Keyvanfar K, Metzger ME, Krouse A, Donahue RE, Kepes S, Gray J, Dunbar CE, Persons DA, Nienhuis AW. Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus-based lentiviral vector system. Blood. 103: 4062-9. PMID 14976042 DOI: 10.1182/Blood-2004-01-0045 |
0.433 |
|
| 2004 |
Persons DA, Allay JA, Bonifacino A, Lu T, Agricola B, Metzger ME, Donahue RE, Dunbar CE, Sorrentino BP. Transient in vivo selection of transduced peripheral blood cells using antifolate drug selection in rhesus macaques that received transplants with hematopoietic stem cells expressing dihydrofolate reductase vectors. Blood. 103: 796-803. PMID 12920024 DOI: 10.1182/Blood-2003-05-1572 |
0.474 |
|
| 2003 |
Persons DA. Update on gene therapy for hemoglobin disorders. Current Opinion in Molecular Therapeutics. 5: 508-16. PMID 14601520 |
0.358 |
|
| 2003 |
Nienhuis AW, Hanawa H, Sawai N, Sorrentino BP, Persons DA. Development of gene therapy for hemoglobin disorders. Annals of the New York Academy of Sciences. 996: 101-11. PMID 12799288 DOI: 10.1111/J.1749-6632.2003.Tb03238.X |
0.5 |
|
| 2003 |
Persons DA, Allay ER, Sawai N, Hargrove PW, Brent TP, Hanawa H, Nienhuis AW, Sorrentino BP. Successful treatment of murine beta-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells. Blood. 102: 506-13. PMID 12663444 DOI: 10.1182/Blood-2003-03-0677 |
0.459 |
|
| 2002 |
Hanawa H, Persons DA, Nienhuis AW. High-level erythroid lineage-directed gene expression using globin gene regulatory elements after lentiviral vector-mediated gene transfer into primitive human and murine hematopoietic cells. Human Gene Therapy. 13: 2007-16. PMID 12489996 DOI: 10.1089/10430340260395866 |
0.39 |
|
| 2002 |
Leimig T, Mann L, Martin Mdel P, Bonten E, Persons D, Knowles J, Allay JA, Cunningham J, Nienhuis AW, Smeyne R, d'Azzo A. Functional amelioration of murine galactosialidosis by genetically modified bone marrow hematopoietic progenitor cells. Blood. 99: 3169-78. PMID 11964280 DOI: 10.1182/Blood.V99.9.3169 |
0.62 |
|
| 2002 |
Hanawa H, Kelly PF, Nathwani AC, Persons DA, Vandergriff JA, Hargrove P, Vanin EF, Nienhuis AW. Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human blood. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 242-51. PMID 11863413 DOI: 10.1006/mthe.2002.0549 |
0.329 |
|
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