Renato V. Iozzo - Publications

Affiliations: 
Cell and Developmental Biology Thomas Jefferson University 
Area:
Cell Biology, Molecular Biology, General Biology

279 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Galati G, Germanova O, Iozzo RV, Buraschi S, Shchukin YV, Germanov A, Germanov V, Tereshina O, Senni M, Margonato A. Hemodynamic arterial changes in heart failure: a proposed new paradigm of "Heart and Vessels Failure (HVF)". Minerva Cardiology and Angiology. PMID 34100570 DOI: 10.23736/S2724-5683.21.05786-0  1
2021 Neill T, Kapoor A, Xie C, Buraschi S, Iozzo RV. A functional outside-in signaling network of proteoglycans and matrix molecules regulating autophagy. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 33838253 DOI: 10.1016/j.matbio.2021.04.001  1
2021 Dan T, Shastri AA, Palagani A, Buraschi S, Neill T, Savage JE, Kapoor A, DeAngelis T, Addya S, Camphausen K, Iozzo RV, Simone NL. miR-21 Plays a Dual Role in Tumor Formation and Cytotoxic Response in Breast Tumors. Cancers. 13. PMID 33672628 DOI: 10.3390/cancers13040888  1
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Iozzo RV, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.01
2021 Schneider M, Pawlak R, Weber GR, Dillinger AE, Kuespert S, Iozzo RV, Quigley HA, Ohlmann A, Tamm ER, Fuchshofer R. A novel ocular function for decorin in the aqueous humor outflow. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 33582236 DOI: 10.1016/j.matbio.2021.02.002  0.01
2020 Iozzo RV, Theocharis AD, Neill T, Karamanos NK. Complexity of matrix phenotypes. Matrix Biology Plus. 6: 100038. PMID 33543032 DOI: 10.1016/j.mbplus.2020.100038  1
2020 Andreuzzi E, Fejza A, Capuano A, Poletto E, Pivetta E, Doliana R, Pellicani R, Favero A, Maiero S, Fornasarig M, Cannizzaro R, Iozzo RV, Spessotto P, Mongiat M. Deregulated expression of Elastin Microfibril Interfacer 2 (EMILIN2) in gastric cancer affects tumor growth and angiogenesis. Matrix Biology Plus. 6: 100029. PMID 33543026 DOI: 10.1016/j.mbplus.2020.100029  0.01
2020 Kapoor A, Chen CG, Iozzo RV. A simplified aortic ring assay: A useful method to assess biochemical and functional parameters of angiogenesis. Matrix Biology Plus. 6: 100025. PMID 33543023 DOI: 10.1016/j.mbplus.2020.100025  0.01
2020 Buraschi S, Morcavallo A, Neill T, Stefanello M, Palladino C, Xu SQ, Belfiore A, Iozzo RV, Morrione A. Discoidin Domain Receptor 1 functionally interacts with the IGF-I system in bladder cancer. Matrix Biology Plus. 6: 100022. PMID 33543020 DOI: 10.1016/j.mbplus.2020.100022  1
2020 Chen CG, Iozzo RV. Angiostatic cues from the matrix: Endothelial cell autophagy meets hyaluronan biology. The Journal of Biological Chemistry. 295: 16797-16812. PMID 33453912 DOI: 10.1074/jbc.REV120.014391  0.01
2020 Chery DR, Han B, Zhou Y, Wang C, Adams SM, Chandrasekaran P, Kwok B, Heo SJ, Enomoto-Iwamoto M, Lu XL, Kong D, Iozzo RV, Birk DE, Mauck RL, Han L. Decorin Regulates Cartilage Pericellular Matrix Micromechanobiology. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 33246102 DOI: 10.1016/j.matbio.2020.11.002  1
2020 Pantham P, Armstrong DL, Bodnariuc J, Haupt O, Johnson AW, Underhill L, Iozzo RV, Lechner B, Wildman DE. Transcriptomic Profiling of Fetal Membranes of Mice Deficient in Biglycan and Decorin as a Model of Preterm Birth. Biology of Reproduction. PMID 33165521 DOI: 10.1093/biolre/ioaa205  0.01
2020 Mao L, Yang J, Yue J, Chen Y, Zhou H, Fan D, Zhang Q, Buraschi S, Iozzo RV, Bi X. Decorin deficiency promotes epithelial-mesenchymal transition and colon cancer metastasis. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 33065248 DOI: 10.1016/j.matbio.2020.10.001  1
2020 Chen CG, Iozzo RV. Angiostatic cues from the matrix: endothelial cell autophagy meets hyaluronan biology. The Journal of Biological Chemistry. PMID 33020183 DOI: 10.1074/jbc.REV120.014391  0.01
2020 Neill T, Buraschi S, Kapoor A, Iozzo RV. Proteoglycan-driven Autophagy: A Nutrient-independent Mechanism to Control Intracellular Catabolism. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 22155420937370. PMID 32623955 DOI: 10.1369/0022155420937370  1
2020 Buraschi S, Neill T, Xu SQ, Palladino C, Belfiore A, Iozzo RV, Morrione A. Progranulin/EphA2 axis: A novel oncogenic mechanism in bladder cancer. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 32417448 DOI: 10.1016/J.Matbio.2020.03.009  1
2020 Neill T, Chen CG, Buraschi S, Iozzo RV. Catabolic degradation of endothelial VEGFA via autophagy. The Journal of Biological Chemistry. PMID 32209654 DOI: 10.1074/Jbc.Ra120.012593  1
2020 Kapoor A, Chen CG, Iozzo RV. Endorepellin evokes an angiostatic stress signaling cascade in endothelial cells. The Journal of Biological Chemistry. PMID 32205445 DOI: 10.1074/Jbc.Ra120.012525  0.01
2020 Li Q, Han B, Wang C, Tong W, Wei Y, Tseng WJ, Han LH, Liu XS, Enomoto-Iwamoto M, Mauck RL, Qin L, Iozzo RV, Birk DE, Han L. Decorin Mediates Cartilage Matrix Degeneration and Fibrillation in Post-Traumatic Osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 32162789 DOI: 10.1002/Art.41254  1
2020 Chen CG, Gubbiotti MA, Kapoor A, Han X, Yu Y, Linhardt RJ, Iozzo RV. Autophagic degradation of HAS2 in endothelial cells: A novel mechanism to regulate angiogenesis. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 32084457 DOI: 10.1016/J.Matbio.2020.02.001  0.01
2019 Mongiat M, Buraschi S, Andreuzzi E, Neill T, Iozzo RV. Extracellular matrix: the gatekeeper of tumor angiogenesis. Biochemical Society Transactions. PMID 31652436 DOI: 10.1042/Bst20190653  1
2019 Han B, Li Q, Wang C, Patel P, Adams SM, Doyran B, Nia HT, Oftadeh R, Zhou S, Li CY, Liu XS, Lu XL, Enomoto-Iwamoto M, Qin L, Mauck RL, ... Iozzo RV, et al. Decorin Regulates the Aggrecan Network Integrity and Biomechanical Functions of Cartilage Extracellular Matrix. Acs Nano. PMID 31550133 DOI: 10.1021/Acsnano.9B04477  0.01
2019 Pellicani R, Poletto E, Andreuzzi E, Paulitti A, Doliana R, Bizzotto D, Braghetta P, Colladel R, Tarticchio G, Sabatelli P, Bucciotti F, Bressan G, Iozzo RV, Colombatti A, Bonaldo P, et al. Multimerin-2 maintains vascular stability and permeability. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 31422156 DOI: 10.1016/J.Matbio.2019.08.002  0.01
2019 Campbell KR, Chaudhary R, Montano M, Iozzo RV, Bushman WA, Campagnola PJ. Second-harmonic generation microscopy analysis reveals proteoglycan decorin is necessary for proper collagen organization in prostate. Journal of Biomedical Optics. 24: 1-8. PMID 31148435 DOI: 10.1117/1.Jbo.24.6.066501  0.01
2019 Gubbiotti MA, Buraschi S, Kapoor A, Iozzo RV. Proteoglycan signaling in tumor angiogenesis and endothelial cell autophagy. Seminars in Cancer Biology. PMID 31078640 DOI: 10.1016/J.Semcancer.2019.05.003  1
2019 Passi A, Vigetti D, Buraschi S, Iozzo RV. Dissecting the role of hyaluronan synthases in the tumor microenvironment. The Febs Journal. PMID 30974514 DOI: 10.1111/Febs.14847  1
2019 Chen C, Kapoor A, Iozzo RV. Methods for Monitoring Matrix-Induced Autophagy. Methods in Molecular Biology (Clifton, N.J.). 1952: 157-191. PMID 30825174 DOI: 10.1007/978-1-4939-9133-4_14  0.01
2019 Poluzzi C, Nastase MV, Zeng-Brouwers J, Roedig H, Hsieh LT, Michaelis JB, Buhl EM, Rezende F, Manavski Y, Bleich A, Boor P, Brandes RP, Pfeilschifter J, Stelzer EHK, Münch C, ... ... Iozzo RV, et al. Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury. Kidney International. PMID 30712922 DOI: 10.1016/J.Kint.2018.10.037  1
2018 Lin R, Cai J, Kenyon L, Iozzo R, Rosenwasser R, Iacovitti L. Systemic factors trigger vasculature cells to drive Notch signaling and neurogenesis in neural stem cells in the adult brain. Stem Cells (Dayton, Ohio). PMID 30431198 DOI: 10.1002/Stem.2947  0.01
2018 Karamanos NK, Piperigkou Z, Theocharis AD, Watanabe H, Franchi M, Baud S, Brézillon S, Götte M, Passi A, Vigetti D, Ricard-Blum S, Sanderson RD, Neill T, Iozzo RV. Proteoglycan Chemical Diversity Drives Multifunctional Cell Regulation and Therapeutics. Chemical Reviews. PMID 30204432 DOI: 10.1021/Acs.Chemrev.8B00354  1
2018 Karamanos NK, Theocharis AD, Neill T, Iozzo RV. Matrix modeling and remodeling: A biological interplay regulating tissue homeostasis and diseases. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 30130584 DOI: 10.1016/J.Matbio.2018.08.007  1
2018 Gubbiotti MA, Seifert EL, Rodeck U, Hoek JB, Iozzo RV. Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor, decorin. The Journal of Biological Chemistry. PMID 30049794 DOI: 10.1074/Jbc.Ra118.004563  1
2018 Xu SQ, Buraschi S, Tanimoto R, Stefanello M, Belfiore A, Iozzo RV, Morrione A. Analysis of Progranulin-Mediated Akt and MAPK Activation. Methods in Molecular Biology (Clifton, N.J.). 1806: 121-130. PMID 29956273 DOI: 10.1007/978-1-4939-8559-3_9  1
2018 Neill T, Andreuzzi E, Wang ZX, Peiper SC, Mongiat M, Iozzo RV. Endorepellin remodels the endothelial transcriptome toward a pro-autophagic and pro-mitophagic gene signature. The Journal of Biological Chemistry. PMID 29921586 DOI: 10.1074/Jbc.Ra118.002934  1
2018 Bouris P, Manou D, Sopaki-Valalaki A, Kolokotroni A, Moustakas A, Kapoor A, Iozzo RV, Karamanos NK, Theocharis AD. Serglycin promotes breast cancer cell aggressiveness: Induction of epithelial to mesenchymal transition, proteolytic activity and IL-8 signaling. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29842969 DOI: 10.1016/J.Matbio.2018.05.011  0.01
2018 Karalis TT, Heldin P, Vynios DH, Neill T, Buraschi S, Iozzo RV, Karamanos NK, Skandalis SS. Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status: Regulation of hyaluronan/HAS2/CD44 and specific matrix effectors. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29673760 DOI: 10.1016/J.Matbio.2018.04.007  1
2018 Iozzo RV, Gubbiotti MA. Extracellular matrix: The driving force of mammalian diseases. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29625183 DOI: 10.1016/J.Matbio.2018.03.023  0.01
2018 Lin R, Lang M, Heinsinger N, Stricsek G, Zhang J, Iozzo R, Rosenwasser R, Iacovitti L. Stepwise impairment of neural stem cell proliferation and neurogenesis concomitant with disruption of blood-brain barrier in recurrent ischemic stroke. Neurobiology of Disease. PMID 29605425 DOI: 10.1016/J.Nbd.2018.03.013  0.01
2018 Montano M, Dinnon KH, Jacobs L, Xiang W, Iozzo RV, Bushman W. Dual Regulation of Decorin by Androgen and Hedgehog Signaling During Prostate Morphogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 29368411 DOI: 10.1002/Dvdy.24619  0.01
2017 Buraschi S, Neill T, Iozzo RV. Decorin is a devouring proteoglycan: Remodeling of intracellular catabolism via autophagy and mitophagy. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29080840 DOI: 10.1016/J.Matbio.2017.10.005  1
2017 Galvagni F, Nardi F, Spiga O, Trezza A, Tarticchio G, Pellicani R, Andreuzzi E, Caldi E, Toti P, Tosi GM, Santucci A, Iozzo RV, Mongiat M, Orlandini M. Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28912033 DOI: 10.1016/J.Matbio.2017.08.003  0.01
2017 Robinson KA, Sun M, Barnum CE, Weiss SN, Huegel J, Shetye SS, Lin L, Saez D, Adams SM, Iozzo RV, Soslowsky LJ, Birk DE. Decorin and biglycan are necessary for maintaining collagen fibril structure, fiber realignment, and mechanical properties of mature tendons. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28882761 DOI: 10.1016/J.Matbio.2017.08.004  1
2017 Neill T, Sharpe C, Owens RT, Iozzo RV. Decorin-Evoked Paternally Expressed Gene 3 (PEG3) is an Upstream Regulator of the Transcription Factor EB (TFEB) in Endothelial Cell Autophagy. The Journal of Biological Chemistry. PMID 28798237 DOI: 10.1074/Jbc.M116.769950  1
2017 Andreuzzi E, Colladel R, Pellicani R, Tarticchio G, Cannizzaro R, Spessotto P, Bussolati B, Brossa A, De Paoli P, Canzonieri V, Iozzo RV, Colombatti A, Mongiat M. The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28435016 DOI: 10.1016/J.Matbio.2017.04.002  0.01
2017 Tanimoto R, Palladino C, Xu SQ, Buraschi S, Neill T, Gomella LG, Peiper SC, Belfiore A, Iozzo RV, Morrione A. The perlecan-interacting growth factor progranulin regulates ubiquitination, sorting, and lysosomal degradation of sortilin. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28433812 DOI: 10.1016/J.Matbio.2017.04.001  1
2017 Nallasamy S, Yoshida K, Akins M, Myers K, Iozzo R, Mahendroo M. Steroid hormones are key modulators of tissue mechanical function via regulation of collagen and elastic fibers. Endocrinology. PMID 28204185 DOI: 10.1210/En.2016-1930  0.01
2017 Torres A, Gubbiotti MA, Iozzo RV. Decorin-inducible Peg3 Evokes Beclin 1-mediated Autophagy and Thrombospondin 1-mediated Angiostasis. The Journal of Biological Chemistry. PMID 28174297 DOI: 10.1074/Jbc.M116.753632  1
2017 Tanimoto R, Palladino C, Buraschi S, Xu S, Gomella LG, Iozzo RV, Belfiore A, Morrione A. Abstract 1344: Progranulin promotes ubiquitination, sorting and lysosomal degradation of sortilin in castration-resistant prostate cancer cells Cancer Research. 77: 1344-1344. DOI: 10.1158/1538-7445.Am2017-1344  1
2016 Pozzi A, Yurchenco PD, Iozzo RV. The nature and biology of basement membranes. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28040522 DOI: 10.1016/J.Matbio.2016.12.009  1
2016 Neill T, Buraschi S, Goyal A, Sharpe C, Natkanski E, Schaefer L, Morrione A, Iozzo RV. EphA2 is a functional receptor for the growth factor progranulin. The Journal of Cell Biology. PMID 27903606 DOI: 10.1083/Jcb.201603079  1
2016 Schaefer L, Tredup C, Gubbiotti MA, Iozzo RV. Proteoglycan neofunctions: Regulation of inflammation and autophagy in cancer biology. The Febs Journal. PMID 27860287 DOI: 10.1111/Febs.13963  1
2016 Gubbiotti MA, Vallet SD, Ricard-Blum S, Iozzo RV. Decorin interacting network: A comprehensive analysis of decorin-binding partners and their versatile functions. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27693454 DOI: 10.1016/J.Matbio.2016.09.009  0.01
2016 Gubbiotti MA, Neill T, Iozzo RV. A current view of perlecan in physiology and pathology: A mosaic of functions. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27613501 DOI: 10.1016/J.Matbio.2016.09.003  1
2016 Frey H, Moreth K, Hsieh LT, Zeng-Brouwers J, Rathkolb B, Fuchs H, Gailus-Durner V, Iozzo RV, de Angelis MH, Schaefer L. A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia. Glycoconjugate Journal. PMID 27600268 DOI: 10.1007/S10719-016-9722-Y  1
2016 Barallobre-Barreiro J, Gupta SK, Zoccarato A, Kitazume-Taneike R, Fava M, Yin X, Werner T, Hirt MN, Zampetaki A, Viviano A, Chong M, Bern M, Kourliouros A, Domenech N, Willeit P, ... ... Iozzo RV, et al. Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation. Circulation. PMID 27559042 DOI: 10.1161/CIRCULATIONAHA.115.016423  1
2016 Tanimoto R, Lu KG, Xu SQ, Buraschi S, Belfiore A, Iozzo RV, Morrione A. Mechanisms of Progranulin Action and Regulation in Genitourinary Cancers. Frontiers in Endocrinology. 7: 100. PMID 27512385 DOI: 10.3389/Fendo.2016.00100  1
2016 Lu H, Wang T, Li J, Fedele C, Liu Q, Zhang J, Jiang Z, Jain D, Iozzo RV, Violette SM, Weinreb PH, Davis RJ, Gioeli D, Fitzgerald TJ, Altieri DC, et al. αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer Through JNK1-Mediated Activation of Androgen Receptor. Cancer Research. PMID 27450452 DOI: 10.1158/0008-5472.Can-16-0543  1
2016 Goyal A, Gubbiotti MA, Chery DR, Han L, Iozzo RV. Endorepellin-evoked autophagy contributes to angiostasis. The Journal of Biological Chemistry. PMID 27435676 DOI: 10.1074/Jbc.M116.740266  1
2016 Gronau T, Krüger K, Prein C, Aszodi A, Gronau I, Iozzo RV, Mooren FC, Clausen-Schaumann H, Bertrand J, Pap T, Bruckner P, Dreier R. Forced exercise-induced osteoarthritis is attenuated in mice lacking the small leucine-rich proteoglycan decorin. Annals of the Rheumatic Diseases. PMID 27377816 DOI: 10.1136/Annrheumdis-2016-209319  0.01
2016 DeRita RM, Zerlanko B, Singh A, Lu H, Iozzo RV, Benovic JL, Languino LR. c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase Are Enriched into Prostate Cancer Cell Exosomes. Journal of Cellular Biochemistry. PMID 27232975 DOI: 10.1002/Jcb.25611  0.01
2016 Buraschi S, Xu SQ, Stefanello M, Moskalev I, Morcavallo A, Genua M, Tanimoto R, Birbe R, Peiper SC, Gomella LG, Belfiore A, Black PC, Iozzo RV, Morrione A. Suppression of progranulin expression inhibits bladder cancer growth and sensitizes cancer cells to cisplatin. Oncotarget. PMID 27220888 DOI: 10.18632/Oncotarget.9556  1
2016 Nastase MV, Zeng-Brouwers J, Frey H, Hsieh LT, Poluzzi C, Beckmann J, Schroeder N, Pfeilschifter J, Lopez-Mosqueda J, Mersmann J, Ikeda F, Iozzo RV, Dikic I, Schaefer L. An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis. The American Journal of Pathology. 186: 1206-20. PMID 26968342 DOI: 10.1016/J.Ajpath.2015.12.026  1
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Iozzo RV, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.01
2016 Neill T, Schaefer L, Iozzo RV. Decorin as a multivalent therapeutic agent against cancer. Advanced Drug Delivery Reviews. 97: 174-85. PMID 26522384 DOI: 10.1016/J.Addr.2015.10.016  1
2016 Poluzzi C, Iozzo RV, Schaefer L. Endostatin and endorepellin: A common route of action for similar angiostatic cancer avengers. Advanced Drug Delivery Reviews. 97: 156-73. PMID 26518982 DOI: 10.1016/J.Addr.2015.10.012  1
2016 Buraschi S, Xu S, Stefanello M, Moskalev I, Morcavallo A, Genua M, Tanimoto R, Neill T, Peiper SC, Gomella LG, Belfiore A, Black PC, Iozzo RV, Morrione A. Abstract 698: Progranulin targeting in urothelial cancer cells inhibits motility, tumor growthin vitroandin vivoand sensitizes cells to cisplatin Cancer Research. 76: 698-698. DOI: 10.1158/1538-7445.Am2016-698  1
2016 Nastase MV, Zeng-Brouwers J, Frey H, Hsieh LTH, Poluzzi C, Beckmann J, Schroeder N, Pfeilschifter J, Lopez-Mosqueda J, Mersmann J, Ikeda F, Iozzo RV, Dikic I, Schaefer L. An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis American Journal of Pathology. 186: 1206-1220. DOI: 10.1016/j.ajpath.2015.12.026  1
2015 Neill T, Schaefer L, Iozzo RV. Oncosuppressive functions of decorin. Molecular & Cellular Oncology. 2: e975645. PMID 27308453 DOI: 10.4161/23723556.2014.975645  1
2015 Hsieh LT, Frey H, Nastase MV, Tredup C, Hoffmann A, Poluzzi C, Zeng-Brouwers J, Manon-Jensen T, Schröder K, Brandes RP, Iozzo RV, Schaefer L. Bimodal role of NADPH oxidases in the regulation of biglycan-triggered IL-1β synthesis. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 26689330 DOI: 10.1016/J.Matbio.2015.12.005  1
2015 Bi X, Xia X, Fan D, Mu T, Zhang Q, Iozzo RD, Yang W. Oncogenic activin C interacts with decorin in colorectal cancer in vivo and in vitro. Molecular Carcinogenesis. PMID 26509701 DOI: 10.1002/Mc.22427  1
2015 Yang Y, Xu WW, Neill T, Hu Z, Wang CH, Xiao X, Stock S, Guise T, Yun CO, Brendler CB, Iozzo RV, Seth P. Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases. Human Gene Therapy. PMID 26467629 DOI: 10.1089/Hum.2015.098  1
2015 Gubbiotti MA, Iozzo RV. Proteoglycans regulate autophagy via outside-in signaling: an emerging new concept. Matrix Biology : Journal of the International Society For Matrix Biology. 48: 6-13. PMID 26462577 DOI: 10.1016/J.Matbio.2015.10.002  0.01
2015 Gubbiotti MA, Neill T, Frey H, Schaefer L, Iozzo RV. Decorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagy. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 26344480 DOI: 10.1016/J.Matbio.2015.09.001  1
2015 Douglass S, Goyal A, Iozzo RV. The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy. Connective Tissue Research. 56: 381-91. PMID 26181327 DOI: 10.3109/03008207.2015.1045297  1
2015 Neill T, Schaefer L, Iozzo RV. Decoding the Matrix: Instructive Roles of Proteoglycan Receptors. Biochemistry. 54: 4583-98. PMID 26177309 DOI: 10.1021/Acs.Biochem.5B00653  1
2015 de Miranda de Araujo LB, Horgan CE, Aron A, Iozzo RV, Lechner BE. Compensatory fetal membrane mechanisms between biglycan and decorin in inflammation. Molecular Reproduction and Development. 82: 387-96. PMID 25914258 DOI: 10.1002/Mrd.22488  1
2015 Gordon JA, Freedman BR, Zuskov A, Iozzo RV, Birk DE, Soslowsky LJ. Achilles tendons from decorin- and biglycan-null mouse models have inferior mechanical and structural properties predicted by an image-based empirical damage model. Journal of Biomechanics. 48: 2110-5. PMID 25888014 DOI: 10.1016/J.Jbiomech.2015.02.058  1
2015 Malaguarnera R, Nicolosi ML, Sacco A, Morcavallo A, Vella V, Voci C, Spatuzza M, Xu SQ, Iozzo RV, Vigneri R, Morrione A, Belfiore A. Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses. Oncotarget. PMID 25840417 DOI: 10.18632/Oncotarget.3177  1
2015 Xu SQ, Buraschi S, Morcavallo A, Genua M, Shirao T, Peiper SC, Gomella LG, Birbe R, Belfiore A, Iozzo RV, Morrione A. A novel role for drebrin in regulating progranulin bioactivity in bladder cancer. Oncotarget. 6: 10825-39. PMID 25839164 DOI: 10.18632/Oncotarget.3424  1
2015 Theocharis AD, Skandalis SS, Neill T, Multhaupt HA, Hubo M, Frey H, Gopal S, Gomes A, Afratis N, Lim HC, Couchman JR, Filmus J, Sanderson RD, Schaefer L, Iozzo RV, et al. Insights into the key roles of proteoglycans in breast cancer biology and translational medicine. Biochimica Et Biophysica Acta. 1855: 276-300. PMID 25829250 DOI: 10.1016/J.Bbcan.2015.03.006  1
2015 Iozzo RV, Neill T. Cosmetics for the matrix: An attractive new style for Matrix Biology. Matrix Biology : Journal of the International Society For Matrix Biology. 42: 8-10. PMID 25746590 DOI: 10.1016/J.Matbio.2015.02.013  1
2015 Borges MC, Narayanan V, Iozzo RV, Ludwig MS. Deficiency of decorin induces expression of Foxp3 in CD4(+) CD25(+) T cells in a murine model of allergic asthma. Respirology (Carlton, Vic.). 20: 904-11. PMID 25712878 DOI: 10.1111/Resp.12485  1
2015 Iozzo RV, Schaefer L. Proteoglycan form and function: A comprehensive nomenclature of proteoglycans. Matrix Biology : Journal of the International Society For Matrix Biology. 42: 11-55. PMID 25701227 DOI: 10.1016/J.Matbio.2015.02.003  1
2015 Fedele C, Singh A, Zerlanko BJ, Iozzo RV, Languino LR. The αvβ6 integrin is transferred intercellularly via exosomes. The Journal of Biological Chemistry. 290: 4545-51. PMID 25568317 DOI: 10.1074/Jbc.C114.617662  1
2015 Xu W, Neill T, Yang Y, Hu Z, Cleveland E, Wu Y, Hutten R, Xiao X, Stock SR, Shevrin D, Kaul K, Brendler C, Iozzo RV, Seth P. The systemic delivery of an oncolytic adenovirus expressing decorin inhibits bone metastasis in a mouse model of human prostate cancer. Gene Therapy. 22: 31-40. PMID 25503693 DOI: 10.1038/Gt.2014.110  1
2015 Tanimoto R, Morcavallo A, Terracciano M, Xu SQ, Stefanello M, Buraschi S, Lu KG, Bagley DH, Gomella LG, Scotlandi K, Belfiore A, Iozzo RV, Morrione A. Sortilin regulates progranulin action in castration-resistant prostate cancer cells. Endocrinology. 156: 58-70. PMID 25365768 DOI: 10.1210/En.2014-1590  1
2015 Xu S, Buraschi S, Morcavallo A, Genua M, Shirao T, Peiper SC, Gomella LG, Belfiore A, Iozzo RV, Morrione A. Abstract 4945: A novel role for drebrin in regulating progranulin bioactivity in bladder cancer Cancer Research. 75: 4945-4945. DOI: 10.1158/1538-7445.Am2015-4945  1
2015 Singh A, Fedele C, Iozzo RV, Languino LR. Abstract 357: Exosome-mediated transfer of alphaV integrins promotes prostate cancer cell-cell communication Cancer Research. 75: 357-357. DOI: 10.1158/1538-7445.Am2015-357  0.01
2014 Morcavallo A, Stefanello M, Iozzo RV, Belfiore A, Morrione A. Ligand-mediated endocytosis and trafficking of the insulin-like growth factor receptor I and insulin receptor modulate receptor function. Frontiers in Endocrinology. 5: 220. PMID 25566192 DOI: 10.3389/Fendo.2014.00220  0.01
2014 Theocharis AD, Gialeli C, Bouris P, Giannopoulou E, Skandalis SS, Aletras AJ, Iozzo RV, Karamanos NK. Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer. The Febs Journal. 281: 5023-42. PMID 25333340 DOI: 10.1111/Febs.12927  0.01
2014 Hsieh LT, Nastase MV, Zeng-Brouwers J, Iozzo RV, Schaefer L. Soluble biglycan as a biomarker of inflammatory renal diseases. The International Journal of Biochemistry & Cell Biology. 54: 223-35. PMID 25091702 DOI: 10.1016/J.Biocel.2014.07.020  1
2014 Neill T, Schaefer L, Iozzo RV. Instructive roles of extracellular matrix on autophagy. The American Journal of Pathology. 184: 2146-53. PMID 24976620 DOI: 10.1016/J.Ajpath.2014.05.010  1
2014 Poluzzi C, Casulli J, Goyal A, Mercer TJ, Neill T, Iozzo RV. Endorepellin evokes autophagy in endothelial cells. The Journal of Biological Chemistry. 289: 16114-28. PMID 24737315 DOI: 10.1074/Jbc.M114.556530  1
2014 Goyal A, Neill T, Owens RT, Schaefer L, Iozzo RV. Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 42-50. PMID 24726292 DOI: 10.1016/J.Matbio.2014.04.002  1
2014 Lord MS, Chuang CY, Melrose J, Davies MJ, Iozzo RV, Whitelock JM. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 112-22. PMID 24509440 DOI: 10.1016/J.Matbio.2014.01.016  1
2014 Nastase MV, Iozzo RV, Schaefer L. Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology. Biochimica Et Biophysica Acta. 1840: 2460-70. PMID 24508120 DOI: 10.1016/J.Bbagen.2014.01.035  1
2014 Moreth K, Frey H, Hubo M, Zeng-Brouwers J, Nastase MV, Hsieh LT, Haceni R, Pfeilschifter J, Iozzo RV, Schaefer L. Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 143-51. PMID 24480070 DOI: 10.1016/J.Matbio.2014.01.010  1
2014 Goyal A, Neill T, Owens RT, Schaefer L, Iozzo RV. Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells. Matrix Biology : Journal of the International Society For Matrix Biology. 34: 46-54. PMID 24472739 DOI: 10.1016/J.Matbio.2013.12.011  1
2014 Nikolovska K, Renke JK, Jungmann O, Grobe K, Iozzo RV, Zamfir AD, Seidler DG. A decorin-deficient matrix affects skin chondroitin/dermatan sulfate levels and keratinocyte function. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 91-102. PMID 24447999 DOI: 10.1016/J.Matbio.2014.01.003  1
2014 Neill T, Torres A, Buraschi S, Owens RT, Hoek JB, Baffa R, Iozzo RV. Decorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin. The Journal of Biological Chemistry. 289: 4952-68. PMID 24403067 DOI: 10.1074/Jbc.M113.512566  1
2014 Morcavallo A, Buraschi S, Xu SQ, Belfiore A, Schaefer L, Iozzo RV, Morrione A. Decorin differentially modulates the activity of insulin receptor isoform A ligands. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 82-90. PMID 24389353 DOI: 10.1016/J.Matbio.2013.12.010  1
2014 Wu Z, Horgan CE, Carr O, Owens RT, Iozzo RV, Lechner BE. Biglycan and decorin differentially regulate signaling in the fetal membranes. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 266-75. PMID 24373743 DOI: 10.1016/J.Matbio.2013.12.006  1
2014 Zeng-Brouwers J, Beckmann J, Nastase MV, Iozzo RV, Schaefer L. De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 132-42. PMID 24361484 DOI: 10.1016/J.Matbio.2013.12.003  1
2014 Horváth Z, Kovalszky I, Fullár A, Kiss K, Schaff Z, Iozzo RV, Baghy K. Decorin deficiency promotes hepatic carcinogenesis. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 194-205. PMID 24361483 DOI: 10.1016/J.Matbio.2013.11.004  0.01
2014 Fetting JL, Guay JA, Karolak MJ, Iozzo RV, Adams DC, Maridas DE, Brown AC, Oxburgh L. FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney. Development (Cambridge, England). 141: 17-27. PMID 24284212 DOI: 10.1242/Dev.089078  1
2014 Dunkman AA, Buckley MR, Mienaltowski MJ, Adams SM, Thomas SJ, Kumar A, Beason DP, Iozzo RV, Birk DE, Soslowsky LJ. The injury response of aged tendons in the absence of biglycan and decorin. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 232-8. PMID 24157578 DOI: 10.1016/J.Matbio.2013.10.008  1
2014 Romanello M, Piatkowska E, Antoniali G, Cesaratto L, Vascotto C, Iozzo RV, Delneri D, Brancia FL. Osteoblastic cell secretome: a novel role for progranulin during risedronate treatment. Bone. 58: 81-91. PMID 24120669 DOI: 10.1016/J.Bone.2013.10.003  0.01
2014 Dunkman AA, Buckley MR, Mienaltowski MJ, Adams SM, Thomas SJ, Satchell L, Kumar A, Pathmanathan L, Beason DP, Iozzo RV, Birk DE, Soslowsky LJ. The tendon injury response is influenced by decorin and biglycan. Annals of Biomedical Engineering. 42: 619-30. PMID 24072490 DOI: 10.1007/S10439-013-0915-2  1
2014 Morcavallo A, Stefanello M, Iozzo RV, Belfiore A, Morrione A. Ligand-mediated endocytosis and trafficking of the insulin-like growth factor receptor I and insulin receptor modulate receptor function Frontiers in Endocrinology. 5. DOI: 10.3389/fendo.2014.00220  1
2014 Morcavallo A, Buraschi S, Xu S, Gomella LG, Belfiore A, Iozzo RV, Morrione A. Abstract 4415: Discoidin domain receptor 1 (DDR1) and IGF-I system crosstalk in bladder cancer progression Cancer Research. 74: 4415-4415. DOI: 10.1158/1538-7445.Am2014-4415  1
2013 Neill T, Torres A, Buraschi S, Iozzo RV. Decorin has an appetite for endothelial cell autophagy. Autophagy. 9: 1626-8. PMID 23989617 DOI: 10.4161/Auto.25881  1
2013 Buckley MR, Huffman GR, Iozzo RV, Birk DE, Soslowsky LJ. The location-specific role of proteoglycans in the flexor carpi ulnaris tendon. Connective Tissue Research. 54: 367-73. PMID 23941206 DOI: 10.3109/03008207.2013.832232  1
2013 Buraschi S, Neill T, Goyal A, Poluzzi C, Smythies J, Owens RT, Schaefer L, Torres A, Iozzo RV. Decorin causes autophagy in endothelial cells via Peg3. Proceedings of the National Academy of Sciences of the United States of America. 110: E2582-91. PMID 23798385 DOI: 10.1073/Pnas.1305732110  1
2013 Iozzo RV. A giant of matrix biology: a celebration of Dick Heinegård's life. Matrix Biology : Journal of the International Society For Matrix Biology. 32: 215-9. PMID 23721659 DOI: 10.1016/J.Matbio.2013.05.002  0.01
2013 Chen S, Sun M, Iozzo RV, Kao WW, Birk DE. Intracellularly-retained decorin lacking the C-terminal ear repeat causes ER stress: a cell-based etiological mechanism for congenital stromal corneal dystrophy. The American Journal of Pathology. 183: 247-56. PMID 23685109 DOI: 10.1016/J.Ajpath.2013.04.001  1
2013 Vlodavsky I, Iozzo RV, Sanderson RD. Heparanase: multiple functions in inflammation, diabetes and atherosclerosis. Matrix Biology : Journal of the International Society For Matrix Biology. 32: 220-2. PMID 23499526 DOI: 10.1016/J.Matbio.2013.03.001  0.01
2013 Bocian C, Urbanowitz AK, Owens RT, Iozzo RV, Götte M, Seidler DG. Decorin potentiates interferon-γ activity in a model of allergic inflammation. The Journal of Biological Chemistry. 288: 12699-711. PMID 23460644 DOI: 10.1074/Jbc.M112.419366  1
2013 Baghy K, Horváth Z, RegÅ‘s E, Kiss K, Schaff Z, Iozzo RV, Kovalszky I. Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis. The Febs Journal. 280: 2150-64. PMID 23448253 DOI: 10.1111/Febs.12215  0.01
2013 Willis CD, Poluzzi C, Mongiat M, Iozzo RV. Endorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cells. The Febs Journal. 280: 2271-84. PMID 23374253 DOI: 10.1111/Febs.12164  1
2013 Morrione A, Neill T, Iozzo RV. Dichotomy of decorin activity on the insulin-like growth factor-I system. The Febs Journal. 280: 2138-49. PMID 23351020 DOI: 10.1111/Febs.12149  1
2013 Neill T, Jones HR, Crane-Smith Z, Owens RT, Schaefer L, Iozzo RV. Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1. The Febs Journal. 280: 2353-68. PMID 23350987 DOI: 10.1111/Febs.12148  1
2013 Frey H, Schroeder N, Manon-Jensen T, Iozzo RV, Schaefer L. Biological interplay between proteoglycans and their innate immune receptors in inflammation. The Febs Journal. 280: 2165-79. PMID 23350913 DOI: 10.1111/Febs.12145  1
2013 Jung M, Lord MS, Cheng B, Lyons JG, Alkhouri H, Hughes JM, McCarthy SJ, Iozzo RV, Whitelock JM. Mast cells produce novel shorter forms of perlecan that contain functional endorepellin: a role in angiogenesis and wound healing. The Journal of Biological Chemistry. 288: 3289-304. PMID 23235151 DOI: 10.1074/Jbc.M112.387811  1
2013 Dunkman AA, Buckley MR, Mienaltowski MJ, Adams SM, Thomas SJ, Satchell L, Kumar A, Pathmanathan L, Beason DP, Iozzo RV, Birk DE, Soslowsky LJ. Decorin expression is important for age-related changes in tendon structure and mechanical properties. Matrix Biology : Journal of the International Society For Matrix Biology. 32: 3-13. PMID 23178232 DOI: 10.1016/J.Matbio.2012.11.005  1
2012 Jungmann O, Nikolovska K, Stock C, Schulz JN, Eckes B, Riethmüller C, Owens RT, Iozzo RV, Seidler DG. The dermatan sulfate proteoglycan decorin modulates α2β1 integrin and the vimentin intermediate filament system during collagen synthesis. Plos One. 7: e50809. PMID 23226541 DOI: 10.1371/Journal.Pone.0050809  1
2012 Goyal A, Poluzzi C, Willis CD, Smythies J, Shellard A, Neill T, Iozzo RV. Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear factor of activated T cell 1 (NFAT1) activation. The Journal of Biological Chemistry. 287: 43543-56. PMID 23060442 DOI: 10.1074/Jbc.M112.401786  1
2012 Buraschi S, Neill T, Owens RT, Iniguez LA, Purkins G, Vadigepalli R, Evans B, Schaefer L, Peiper SC, Wang ZX, Iozzo RV. Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model. Plos One. 7: e45559. PMID 23029096 DOI: 10.1371/Journal.Pone.0045559  1
2012 Nikitovic D, Aggelidakis J, Young MF, Iozzo RV, Karamanos NK, Tzanakakis GN. The biology of small leucine-rich proteoglycans in bone pathophysiology. The Journal of Biological Chemistry. 287: 33926-33. PMID 22879588 DOI: 10.1074/Jbc.R112.379602  1
2012 Genua M, Xu SQ, Buraschi S, Peiper SC, Gomella LG, Belfiore A, Iozzo RV, Morrione A. Proline-rich tyrosine kinase 2 (Pyk2) regulates IGF-I-induced cell motility and invasion of urothelial carcinoma cells. Plos One. 7: e40148. PMID 22859931 DOI: 10.1371/Journal.Pone.0040148  1
2012 Neill T, Schaefer L, Iozzo RV. Decorin: a guardian from the matrix. The American Journal of Pathology. 181: 380-7. PMID 22735579 DOI: 10.1016/J.Ajpath.2012.04.029  1
2012 Sanderson RD, Iozzo RV. Targeting heparanase for cancer therapy at the tumor-matrix interface. Matrix Biology : Journal of the International Society For Matrix Biology. 31: 283-4. PMID 22655968 DOI: 10.1016/J.Matbio.2012.05.001  0.01
2012 Moreth K, Iozzo RV, Schaefer L. Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation. Cell Cycle (Georgetown, Tex.). 11: 2084-91. PMID 22580469 DOI: 10.4161/Cc.20316  1
2012 Dourte LM, Pathmanathan L, Jawad AF, Iozzo RV, Mienaltowski MJ, Birk DE, Soslowsky LJ. Influence of decorin on the mechanical, compositional, and structural properties of the mouse patellar tendon. Journal of Biomechanical Engineering. 134: 031005. PMID 22482685 DOI: 10.1115/1.4006200  1
2012 Schaefer L, Iozzo RV. Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation. Current Opinion in Genetics & Development. 22: 56-7. PMID 22326829 DOI: 10.1016/J.Gde.2011.12.002  1
2012 Morcavallo A, Genua M, Palummo A, Kletvikova E, Jiracek J, Brzozowski AM, Iozzo RV, Belfiore A, Morrione A. Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A. The Journal of Biological Chemistry. 287: 11422-36. PMID 22318726 DOI: 10.1074/Jbc.M111.252478  0.01
2012 Murphy-Ullrich JE, Iozzo RV. Thrombospondins in physiology and disease: new tricks for old dogs. Matrix Biology : Journal of the International Society For Matrix Biology. 31: 152-4. PMID 22265891 DOI: 10.1016/J.Matbio.2012.01.002  1
2012 Baghy K, Iozzo RV, Kovalszky I. Decorin-TGFβ axis in hepatic fibrosis and cirrhosis. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 60: 262-8. PMID 22260996 DOI: 10.1369/0022155412438104  0.01
2012 Wu Z, Aron AW, Macksoud EE, Iozzo RV, Hai CM, Lechner BE. Uterine dysfunction in biglycan and decorin deficient mice leads to dystocia during parturition. Plos One. 7: e29627. PMID 22253749 DOI: 10.1371/Journal.Pone.0029627  1
2012 Neill T, Painter H, Buraschi S, Owens RT, Lisanti MP, Schaefer L, Iozzo RV. Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3. The Journal of Biological Chemistry. 287: 5492-506. PMID 22194599 DOI: 10.1074/Jbc.M111.283499  1
2012 Bi X, Pohl NM, Qian Z, Yang GR, Gou Y, Guzman G, Kajdacsy-Balla A, Iozzo RV, Yang W. Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice. Carcinogenesis. 33: 326-30. PMID 22159220 DOI: 10.1093/Carcin/Bgr293  1
2012 Ichii M, Frank MB, Iozzo RV, Kincade PW. The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells. Blood. 119: 1683-92. PMID 22117039 DOI: 10.1182/Blood-2011-07-369199  0.01
2012 Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Iozzo R, ... ... Iozzo RV, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127  1
2011 Merline R, Moreth K, Beckmann J, Nastase MV, Zeng-Brouwers J, Tralhão JG, Lemarchand P, Pfeilschifter J, Schaefer RM, Iozzo RV, Schaefer L. Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21. Science Signaling. 4: ra75. PMID 22087031 DOI: 10.1126/Scisignal.2001868  1
2011 Seidler DG, Mohamed NA, Bocian C, Stadtmann A, Hermann S, Schäfers K, Schäfers M, Iozzo RV, Zarbock A, Götte M. The role for decorin in delayed-type hypersensitivity. Journal of Immunology (Baltimore, Md. : 1950). 187: 6108-19. PMID 22043007 DOI: 10.4049/Jimmunol.1100373  1
2011 Iozzo RV. Autophagic tumor stroma: a biofuel for cancer growth. Cell Cycle (Georgetown, Tex.). 10: 3231-2. PMID 21946523 DOI: 10.4161/Cc.10.19.17124  0.01
2011 Chen S, Sun M, Meng X, Iozzo RV, Kao WW, Birk DE. Pathophysiological mechanisms of autosomal dominant congenital stromal corneal dystrophy: C-terminal-truncated decorin results in abnormal matrix assembly and altered expression of small leucine-rich proteoglycans. The American Journal of Pathology. 179: 2409-19. PMID 21893019 DOI: 10.1016/J.Ajpath.2011.07.026  1
2011 Iozzo RV, Buraschi S, Genua M, Xu SQ, Solomides CC, Peiper SC, Gomella LG, Owens RC, Morrione A. Decorin antagonizes IGF receptor I (IGF-IR) function by interfering with IGF-IR activity and attenuating downstream signaling. The Journal of Biological Chemistry. 286: 34712-21. PMID 21840990 DOI: 10.1074/Jbc.M111.262766  1
2011 Castello-Cros R, Whitaker-Menezes D, Molchansky A, Purkins G, Soslowsky LJ, Beason DP, Sotgia F, Iozzo RV, Lisanti MP. Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis. Cell Cycle (Georgetown, Tex.). 10: 2140-50. PMID 21670602 DOI: 10.4161/Cc.10.13.16227  1
2011 Goyal A, Pal N, Concannon M, Paul M, Doran M, Poluzzi C, Sekiguchi K, Whitelock JM, Neill T, Iozzo RV. Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism. The Journal of Biological Chemistry. 286: 25947-62. PMID 21596751 DOI: 10.1074/Jbc.M111.243626  1
2011 Fassan M, D'Arca D, Letko J, Vecchione A, Gardiman MP, McCue P, Wildemore B, Rugge M, Shupp-Byrne D, Gomella LG, Morrione A, Iozzo RV, Baffa R. Mitostatin is down-regulated in human prostate cancer and suppresses the invasive phenotype of prostate cancer cells. Plos One. 6: e19771. PMID 21573075 DOI: 10.1371/Journal.Pone.0019771  1
2011 Calmus ML, Macksoud EE, Tucker R, Iozzo RV, Lechner BE. A mouse model of spontaneous preterm birth based on the genetic ablation of biglycan and decorin. Reproduction (Cambridge, England). 142: 183-94. PMID 21502335 DOI: 10.1530/Rep-10-0387  1
2011 Marchica CL, Pinelli V, Borges M, Zummer J, Narayanan V, Iozzo RV, Ludwig MS. A role for decorin in a murine model of allergen-induced asthma. American Journal of Physiology. Lung Cellular and Molecular Physiology. 300: L863-73. PMID 21378022 DOI: 10.1152/Ajplung.00300.2009  1
2011 Iozzo RV, Sanderson RD. Proteoglycans in cancer biology, tumour microenvironment and angiogenesis. Journal of Cellular and Molecular Medicine. 15: 1013-31. PMID 21155971 DOI: 10.1111/J.1582-4934.2010.01236.X  0.01
2011 Trimmer C, Sotgia F, Whitaker-Menezes D, Balliet RM, Eaton G, Martinez-Outschoorn UE, Pavlides S, Howell A, Iozzo RV, Pestell RG, Scherer PE, Capozza F, Lisanti MP. Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts. Cancer Biology & Therapy. 11: 383-94. PMID 21150282 DOI: 10.4161/Cbt.11.4.14101  1
2011 Baghy K, Dezso K, László V, Fullár A, Péterfia B, Paku S, Nagy P, Schaff Z, Iozzo RV, Kovalszky I. Ablation of the decorin gene enhances experimental hepatic fibrosis and impairs hepatic healing in mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 439-51. PMID 20956977 DOI: 10.1038/Labinvest.2010.172  0.01
2011 Morrione A, Genua M, Iozzo RV, Gomella LG. Evaluation of the insulin-like growth factor receptor I and Pyk2 kinase in urothelial carcinomas and effect on motility and invasion of urothelial carcinoma-derived cells. Journal of Clinical Oncology. 29: 254-254. DOI: 10.1200/Jco.2011.29.7_Suppl.254  1
2011 Bi X, Yang GR, Gou Y, Pohl N, Guzman G, Kajdacsy-Balla A, Iozzo RV, Yang W. Abstract 1448: Interaction between decorin and E-cadherin/beta-catenin signaling attenuates colorectal cancer growth and metastasis in vitro and in decorin knockout mice Cancer Research. 71: 1448-1448. DOI: 10.1158/1538-7445.Am2011-1448  0.01
2011 Genua M, Xu S, Gomella LG, Iozzo RV, Morrione A. Abstract 1408: The insulin-like growth factor receptor I and Pyk2 kinase are up-regulated in urothelial carcinomas and promote motility and invasion of urothelial carcinoma-derived cells Cancer Research. 71: 1408-1408. DOI: 10.1158/1538-7445.Am2011-1408  1
2011 Dourte LM, Pathmanathan L, Iozzo RV, Soslowsky LJ. Influence of decorin and biglycan on tensile viscoelastic properties in knockout mice Asme 2011 Summer Bioengineering Conference, Sbc 2011. 679-680. DOI: 10.1115/SBC2011-53397  1
2010 Buraschi S, Pal N, Tyler-Rubinstein N, Owens RT, Neill T, Iozzo RV. Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels. The Journal of Biological Chemistry. 285: 42075-85. PMID 20974860 DOI: 10.1074/Jbc.M110.172841  1
2010 Iozzo RV. Letter from Renato V. Iozzo. Matrix Biology. Matrix Biology : Journal of the International Society For Matrix Biology. 29: 558. PMID 20857549 DOI: 10.1016/S0945-053X(10)00120-4  0.01
2010 Iozzo RV, Schaefer L. Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans. The Febs Journal. 277: 3864-75. PMID 20840584 DOI: 10.1111/J.1742-4658.2010.07797.X  1
2010 Iozzo RV, Karamanos N. Proteoglycans in health and disease: emerging concepts and future directions. The Febs Journal. 277: 3863. PMID 20812984 DOI: 10.1111/J.1742-4658.2010.07796.X  0.01
2010 Chuang CY, Lord MS, Melrose J, Rees MD, Knox SM, Freeman C, Iozzo RV, Whitelock JM. Heparan sulfate-dependent signaling of fibroblast growth factor 18 by chondrocyte-derived perlecan. Biochemistry. 49: 5524-32. PMID 20507176 DOI: 10.1021/Bi1005199  1
2010 Metalli D, Lovat F, Tripodi F, Genua M, Xu SQ, Spinelli M, Alberghina L, Vanoni M, Baffa R, Gomella LG, Iozzo RV, Morrione A. The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin. The American Journal of Pathology. 176: 2997-3006. PMID 20395438 DOI: 10.2353/Ajpath.2010.090904  1
2010 Sanches JC, Jones CJ, Aplin JD, Iozzo RV, Zorn TM, Oliveira SF. Collagen fibril organization in the pregnant endometrium of decorin-deficient mice. Journal of Anatomy. 216: 144-55. PMID 19900179 DOI: 10.1111/J.1469-7580.2009.01170.X  0.01
2010 Rees MD, Whitelock JM, Malle E, Chuang CY, Iozzo RV, Nilasaroya A, Davies MJ. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan. Matrix Biology : Journal of the International Society For Matrix Biology. 29: 63-73. PMID 19788922 DOI: 10.1016/J.Matbio.2009.09.005  1
2010 Ferdous Z, Peterson SB, Tseng H, Anderson DK, Iozzo RV, Grande-Allen KJ. A role for decorin in controlling proliferation, adhesion, and migration of murine embryonic fibroblasts. Journal of Biomedical Materials Research. Part A. 93: 419-28. PMID 19569212 DOI: 10.1002/Jbm.A.32545  1
2010 Metalli D, Lovat F, Tripodi F, Xu S, Alberghina L, Vanoni M, Baffa R, Iozzo RV, Gomella LG, Morrione A. Abstract 5057: The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and MAPK-dependent activation of paxillin Cancer Research. 70: 5057-5057. DOI: 10.1158/1538-7445.Am10-5057  1
2009 Nyström A, Shaik ZP, Gullberg D, Krieg T, Eckes B, Zent R, Pozzi A, Iozzo RV. Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity. Blood. 114: 4897-906. PMID 19789387 DOI: 10.1182/Blood-2009-02-207134  1
2009 San Antonio JD, Zoeller JJ, Habursky K, Turner K, Pimtong W, Burrows M, Choi S, Basra S, Bennett JS, DeGrado WF, Iozzo RV. A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis. The American Journal of Pathology. 175: 1338-47. PMID 19700757 DOI: 10.2353/Ajpath.2009.090234  1
2009 Smith SM, Whitelock JM, Iozzo RV, Little CB, Melrose J. Topographical variation in the distributions of versican, aggrecan and perlecan in the foetal human spine reflects their diverse functional roles in spinal development. Histochemistry and Cell Biology. 132: 491-503. PMID 19669783 DOI: 10.1007/S00418-009-0623-Z  1
2009 Iozzo RV, Zoeller JJ, Nyström A. Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis. Molecules and Cells. 27: 503-13. PMID 19466598 DOI: 10.1007/S10059-009-0069-0  1
2009 Goldoni S, Humphries A, Nyström A, Sattar S, Owens RT, McQuillan DJ, Ireton K, Iozzo RV. Decorin is a novel antagonistic ligand of the Met receptor. The Journal of Cell Biology. 185: 743-54. PMID 19433454 DOI: 10.1083/Jcb.200901129  1
2009 Zoeller JJ, Whitelock JM, Iozzo RV. Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 284-91. PMID 19422911 DOI: 10.1016/J.Matbio.2009.04.010  1
2009 Haruyama N, Sreenath TL, Suzuki S, Yao X, Wang Z, Wang Y, Honeycutt C, Iozzo RV, Young MF, Kulkarni AB. Genetic evidence for key roles of decorin and biglycan in dentin mineralization. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 129-36. PMID 19379665 DOI: 10.1016/J.Matbio.2009.01.005  1
2009 Lovat F, Bitto A, Xu SQ, Fassan M, Goldoni S, Metalli D, Wubah V, McCue P, Serrero G, Gomella LG, Baffa R, Iozzo RV, Morrione A. Proepithelin is an autocrine growth factor for bladder cancer. Carcinogenesis. 30: 861-8. PMID 19237611 DOI: 10.1093/Carcin/Bgp050  1
2009 Zoeller JJ, Pimtong W, Corby H, Goldoni S, Iozzo AE, Owens RT, Ho SY, Iozzo RV. A central role for decorin during vertebrate convergent extension. The Journal of Biological Chemistry. 284: 11728-37. PMID 19211552 DOI: 10.1074/Jbc.M808991200  1
2009 Monami G, Emiliozzi V, Bitto A, Lovat F, Xu SQ, Goldoni S, Fassan M, Serrero G, Gomella LG, Baffa R, Iozzo RV, Morrione A. Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth. The American Journal of Pathology. 174: 1037-47. PMID 19179604 DOI: 10.2353/Ajpath.2009.080735  1
2009 Zhang G, Chen S, Goldoni S, Calder BW, Simpson HC, Owens RT, McQuillan DJ, Young MF, Iozzo RV, Birk DE. Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan. The Journal of Biological Chemistry. 284: 8888-97. PMID 19136671 DOI: 10.1074/Jbc.M806590200  1
2009 Vecchione A, Fassan M, Anesti V, Morrione A, Goldoni S, Baldassarre G, Byrne D, D'Arca D, Palazzo JP, Lloyd J, Scorrano L, Gomella LG, Iozzo RV, Baffa R. MITOSTATIN , a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer Oncogene. 28: 257-269. PMID 18931701 DOI: 10.1038/Onc.2008.381  1
2008 O'Riordan E, Orlova TN, Mendelev N, Patschan D, Kemp R, Chander PN, Hu R, Hao G, Gross SS, Iozzo RV, Delaney V, Goligorsky MS. Urinary proteomic analysis of chronic allograft nephropathy. Proteomics. Clinical Applications. 2: 1025-35. PMID 21136903 DOI: 10.1002/Prca.200780137  1
2008 Goldoni S, Seidler DG, Heath J, Fassan M, Baffa R, Thakur ML, Owens RT, McQuillan DJ, Iozzo RV. An antimetastatic role for decorin in breast cancer. The American Journal of Pathology. 173: 844-55. PMID 18688028 DOI: 10.2353/Ajpath.2008.080275  1
2008 Cailhier JF, Sirois I, Laplante P, Lepage S, Raymond MA, Brassard N, Prat A, Iozzo RV, Pshezhetsky AV, Hébert MJ. Caspase-3 activation triggers extracellular cathepsin L release and endorepellin proteolysis. The Journal of Biological Chemistry. 283: 27220-9. PMID 18658137 DOI: 10.1074/Jbc.M801164200  1
2008 Baker AB, Ettenson DS, Jonas M, Nugent MA, Iozzo RV, Edelman ER. Endothelial cells provide feedback control for vascular remodeling through a mechanosensitive autocrine TGF-beta signaling pathway. Circulation Research. 103: 289-97. PMID 18583708 DOI: 10.1161/Circresaha.108.179465  1
2008 Bi X, Tong C, Dockendorff A, Bancroft L, Gallagher L, Guzman G, Iozzo RV, Augenlicht LH, Yang W. Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation. Carcinogenesis. 29: 1435-40. PMID 18550571 DOI: 10.1093/Carcin/Bgn141  0.01
2008 Schaefer L, Iozzo RV. Biological functions of the small leucine-rich proteoglycans: From genetics to signal transduction Journal of Biological Chemistry. 283: 21305-21309. PMID 18463092 DOI: 10.1074/Jbc.R800020200  1
2008 Zoeller JJ, McQuillan A, Whitelock J, Ho SY, Iozzo RV. A central function for perlecan in skeletal muscle and cardiovascular development. The Journal of Cell Biology. 181: 381-94. PMID 18426981 DOI: 10.1083/Jcb.200708022  1
2008 Ferdous Z, Lazaro LD, Iozzo RV, Höök M, Grande-Allen KJ. Influence of cyclic strain and decorin deficiency on 3D cellularized collagen matrices. Biomaterials. 29: 2740-8. PMID 18394699 DOI: 10.1016/J.Biomaterials.2008.03.018  1
2008 Zoeller JJ, Iozzo RV. Proteomic profiling of endorepellin angiostatic activity on human endothelial cells. Proteome Science. 6: 7. PMID 18269764 DOI: 10.1186/1477-5956-6-7  1
2008 Woodall BP, Nyström A, Iozzo RA, Eble JA, Niland S, Krieg T, Eckes B, Pozzi A, Iozzo RV. Integrin α2β1 is the required receptor for endorepellin angiostatic activity Journal of Biological Chemistry. 283: 2335-2343. PMID 18024432 DOI: 10.1074/Jbc.M708364200  1
2007 Ferdous Z, Wei VM, Iozzo R, Höök M, Grande-Allen KJ. Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices. The Journal of Biological Chemistry. 282: 35887-98. PMID 17942398 DOI: 10.1074/Jbc.M705180200  1
2007 Williams KJ, Qiu G, Usui HK, Dunn SR, McCue P, Bottinger E, Iozzo RV, Sharma K. Decorin deficiency enhances progressive nephropathy in diabetic mice. The American Journal of Pathology. 171: 1441-50. PMID 17884968 DOI: 10.2353/Ajpath.2007.070079  1
2007 Salerno FG, Pinelli V, Pini L, Tuma B, Iozzo RV, Ludwig MS. Effect of PEEP on induced constriction is enhanced in decorin-deficient mice American Journal of Physiology - Lung Cellular and Molecular Physiology. 293: L1111-L1117. PMID 17704190 DOI: 10.1152/Ajplung.00095.2007  1
2007 Schaefer L, Tsalastra W, Babelova A, Baliova M, Minnerup J, Sorokin L, Gröne HJ, Reinhardt DP, Pfeilschifter J, Iozzo RV, Schaefer RM. Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin. The American Journal of Pathology. 170: 301-15. PMID 17200203 DOI: 10.2353/Ajpath.2007.060497  1
2007 Bix G, Iozzo RA, Woodall B, Burrows M, McQuillan A, Campbell S, Fields GB, Iozzo RV. Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the alpha2beta1-integrin receptor. Blood. 109: 3745-8. PMID 17197432 DOI: 10.1182/Blood-2006-08-039925  1
2007 Wadhwa S, Bi Y, Ortiz AT, Embree MC, Kilts T, Iozzo R, Opperman LA, Young MF. Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice. Bone. 40: 861-6. PMID 17188951 DOI: 10.1016/J.Bone.2006.11.003  1
2007 Goldoni S, Iozzo RA, Kay P, Campbell S, McQuillan A, Agnew C, Zhu JX, Keene DR, Reed CC, Iozzo RV. A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity. Oncogene. 26: 368-81. PMID 16847455 DOI: 10.1038/Sj.Onc.1209803  1
2006 Bix G, Castello R, Burrows M, Zoeller JJ, Weech M, Iozzo RA, Cardi C, Thakur ML, Barker CA, Camphausen K, Iozzo RV. Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism. Journal of the National Cancer Institute. 98: 1634-46. PMID 17105986 DOI: 10.1093/Jnci/Djj441  1
2006 Järveläinen H, Puolakkainen P, Pakkanen S, Brown EL, Höök M, Iozzo RV, Sage EH, Wight TN. A role for decorin in cutaneous wound healing and angiogenesis. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 14: 443-52. PMID 16939572 DOI: 10.1111/J.1743-6109.2006.00150.X  1
2006 Laplante P, Raymond MA, Labelle A, Abe J, Iozzo RV, Hébert MJ. Perlecan proteolysis induces an alpha2beta1 integrin- and Src family kinase-dependent anti-apoptotic pathway in fibroblasts in the absence of focal adhesion kinase activation. The Journal of Biological Chemistry. 281: 30383-92. PMID 16882656 DOI: 10.1074/Jbc.M606412200  0.01
2006 Seidler DG, Goldoni S, Agnew C, Cardi C, Thakur ML, Owens RT, McQuillan DJ, Iozzo RV. Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation. The Journal of Biological Chemistry. 281: 26408-18. PMID 16835231 DOI: 10.1074/Jbc.M602853200  1
2006 Zhang G, Ezura Y, Chervoneva I, Robinson PS, Beason DP, Carine ET, Soslowsky LJ, Iozzo RV, Birk DE. Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development. Journal of Cellular Biochemistry. 98: 1436-49. PMID 16518859 DOI: 10.1002/Jcb.20776  1
2006 Sher I, Zisman-Rozen S, Eliahu L, Whitelock JM, Maas-Szabowski N, Yamada Y, Breitkreutz D, Fusenig NE, Arikawa-Hirasawa E, Iozzo RV, Bergman R, Ron D. Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation. The Journal of Biological Chemistry. 281: 5178-87. PMID 16269412 DOI: 10.1074/Jbc.M509500200  1
2005 Zhu JX, Goldoni S, Bix G, Owens RT, McQuillan DJ, Reed CC, Iozzo RV. Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis. The Journal of Biological Chemistry. 280: 32468-79. PMID 15994311 DOI: 10.1074/Jbc.M503833200  1
2005 Bi Y, Stuelten CH, Kilts T, Wadhwa S, Iozzo RV, Robey PG, Chen XD, Young MF. Extracellular matrix proteoglycans control the fate of bone marrow stromal cells. The Journal of Biological Chemistry. 280: 30481-9. PMID 15964849 DOI: 10.1074/Jbc.M500573200  1
2005 Weis SM, Zimmerman SD, Shah M, Covell JW, Omens JH, Ross J, Dalton N, Jones Y, Reed CC, Iozzo RV, McCulloch AD. A role for decorin in the remodeling of myocardial infarction. Matrix Biology : Journal of the International Society For Matrix Biology. 24: 313-24. PMID 15949932 DOI: 10.1016/J.Matbio.2005.05.003  1
2005 Robinson PS, Huang TF, Kazam E, Iozzo RV, Birk DE, Soslowsky LJ. Influence of decorin and biglycan on mechanical properties of multiple tendons in knockout mice. Journal of Biomechanical Engineering. 127: 181-5. PMID 15868800 DOI: 10.1115/1.1835363  1
2005 Reed CC, Waterhouse A, Kirby S, Kay P, Owens RT, McQuillan DJ, Iozzo RV. Decorin prevents metastatic spreading of breast cancer. Oncogene. 24: 1104-10. PMID 15690056 DOI: 10.1038/Sj.Onc.1208329  1
2005 Gonzalez EM, Reed CC, Bix G, Fu J, Zhang Y, Gopalakrishnan B, Greenspan DS, Iozzo RV. BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan Journal of Biological Chemistry. 280: 7080-7087. PMID 15591058 DOI: 10.1074/Jbc.M409841200  1
2005 Fust A, LeBellego F, Iozzo RV, Roughley PJ, Ludwig MS. Alterations in lung mechanics in decorin-deficient mice American Journal of Physiology - Lung Cellular and Molecular Physiology. 288: L159-L166. PMID 15447936 DOI: 10.1152/Ajplung.00089.2004  1
2004 Schönherr E, Sunderkötter C, Schaefer L, Thanos S, Grässel S, Oldberg A, Iozzo RV, Young MF, Kresse H. Decorin deficiency leads to impaired angiogenesis in injured mouse cornea Journal of Vascular Research. 41: 499-508. PMID 15528932 DOI: 10.1159/000081806  1
2004 Liang FT, Brown EL, Wang T, Iozzo RV, Fikrig E. Protective niche for Borrelia burgdorferi to evade humoral immunity. The American Journal of Pathology. 165: 977-85. PMID 15331421 DOI: 10.1016/S0002-9440(10)63359-7  1
2004 Robinson PS, Lin TW, Jawad AF, Iozzo RV, Soslowsky LJ. Investigating tendon fascicle structure-function relationships in a transgenic-age mouse model using multiple regression models. Annals of Biomedical Engineering. 32: 924-31. PMID 15298430 DOI: 10.1023/B:Abme.0000032455.78459.56  1
2004 Schaefer L, Mihalik D, Babelova A, Krzyzankova M, Gröne HJ, Iozzo RV, Young MF, Seidler DG, Lin G, Reinhardt DP, Schaefer RM. Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury. The American Journal of Pathology. 165: 383-96. PMID 15277214 DOI: 10.1016/S0002-9440(10)63305-6  1
2004 Bix G, Fu J, Gonzalez EM, Macro L, Barker A, Campbell S, Zutter MM, Santoro SA, Kim JK, Höök M, Reed CC, Iozzo RV. Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin. The Journal of Cell Biology. 166: 97-109. PMID 15240572 DOI: 10.1083/jcb.200401150  1
2004 Robinson PS, Lin TW, Reynolds PR, Derwin KA, Iozzo RV, Soslowsky LJ. Strain-Rate Sensitive Mechanical Properties of Tendon Fascicles from Mice with Genetically Engineered Alterations in Collagen and Decorin Journal of Biomechanical Engineering. 126: 252-257. PMID 15179856 DOI: 10.1115/1.1695570  1
2004 Goldoni S, Owens RT, McQuillan DJ, Shriver Z, Sasisekharan R, Birk DE, Campbell S, Iozzo RV. Biologically active decorin is a monomer in solution. The Journal of Biological Chemistry. 279: 6606-12. PMID 14660661 DOI: 10.1074/Jbc.M310342200  1
2004 Schönherr E, Sunderkötter C, Schaefer L, Thanos S, Grässel S, Oldberg Å, Iozzo RV, Young MF, Kresse H, Skowasch D, Jabs A, Andrié R, Dinkelbach S, Schiele TM, Wernert N, et al. Contents Vol. 41, 2004 Journal of Vascular Research. 41: 565-566. DOI: 10.1159/000082620  1
2004 Schönherr E, Sunderkötter C, Schaefer L, Thanos S, Grässel S, Oldberg Å, Iozzo RV, Young MF, Kresse H, Skowasch D, Jabs A, Andrié R, Dinkelbach S, Schiele TM, Wernert N, et al. Subject Index Vol. 41, 2004 Journal of Vascular Research. 41: 562-563. DOI: 10.1159/000082619  1
2003 Gonzalez EM, Mongiat M, Slater SJ, Baffa R, Iozzo RV. A novel interaction between perlecan protein core and progranulin: potential effects on tumor growth. The Journal of Biological Chemistry. 278: 38113-6. PMID 12900424 DOI: 10.1074/Jbc.C300310200  1
2003 Sweeney SM, DiLullo G, Slater SJ, Martinez J, Iozzo RV, Lauer-Fields JL, Fields GB, San Antonio JD. Angiogenesis in collagen I requires alpha2beta1 ligation of a GFP*GER sequence and possibly p38 MAPK activation and focal adhesion disassembly. The Journal of Biological Chemistry. 278: 30516-24. PMID 12788934 DOI: 10.1074/Jbc.M304237200  1
2003 Elliott DM, Robinson PS, Gimbel JA, Sarver JJ, Abboud JA, Iozzo RV, Soslowsky LJ. Effect of altered matrix proteins on quasilinear viscoelastic properties in transgenic mouse tail tendons. Annals of Biomedical Engineering. 31: 599-605. PMID 12757203 DOI: 10.1114/1.1567282  1
2003 Kalabis J, Patterson MJ, Enders GH, Marian B, Iozzo RV, Rogler G, Gimotty PA, Herlyn M. Stimulation of human colonic epithelial cells by leukemia inhibitory factor is dependent on collagen-embedded fibroblasts in organotypic culture. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1115-7. PMID 12692084 DOI: 10.1096/Fj.02-0852Fje  1
2003 Mongiat M, Sweeney SM, San Antonio JD, Fu J, Iozzo RV. Endorepellin, a novel inhibitor of angiogenesis derived from the C terminus of perlecan. The Journal of Biological Chemistry. 278: 4238-49. PMID 12435733 DOI: 10.1074/Jbc.M210445200  0.01
2002 Corsi A, Xu T, Chen XD, Boyde A, Liang J, Mankani M, Sommer B, Iozzo RV, Eichstetter I, Robey PG, Bianco P, Young MF. Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues Journal of Bone and Mineral Research. 17: 1180-1189. PMID 12102052 DOI: 10.1359/Jbmr.2002.17.7.1180  1
2002 Grant DS, Yenisey C, Rose RW, Tootell M, Santra M, Iozzo RV. Decorin suppresses tumor cell-mediated angiogenesis. Oncogene. 21: 4765-77. PMID 12101415 DOI: 10.1038/Sj.Onc.1205595  1
2002 Werner J, Saghir M, Warshaw AL, Lewandrowski KB, Laposata M, Iozzo RV, Carter EA, Schatz RJ, Fernández-Del Castillo C. Alcoholic pancreatitis in rats: injury from nonoxidative metabolites of ethanol. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G65-73. PMID 12065293 DOI: 10.1152/Ajpgi.00419.2001  0.01
2002 Schaefer L, Macakova K, Raslik I, Micegova M, Gröne HJ, Schönherr E, Robenek H, Echtermeyer FG, Grässel S, Bruckner P, Schaefer RM, Iozzo RV, Kresse H. Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction. The American Journal of Pathology. 160: 1181-91. PMID 11891213 DOI: 10.1016/S0002-9440(10)64937-1  1
2001 Iozzo RV, Antonio JDS. Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena. Journal of Clinical Investigation. 108: 349-355. PMID 11489925 DOI: 10.1172/Jci13738  0.01
2001 Iozzo RV. Series Introduction: Heparan sulfate proteoglycans: intricate molecules with intriguing functions Journal of Clinical Investigation. 108: 165-167. PMID 11457866 DOI: 10.1172/Jci13560  0.01
2001 Murdoch AD, Iozzo RV. Prokaryotic Expression of Proteoglycans Methods of Molecular Biology. 171: 231-238. PMID 11450233 DOI: 10.1385/1-59259-209-0:231  0.01
2001 Brown EL, Wooten RM, Johnson BJ, Iozzo RV, Smith A, Dolan MC, Guo BP, Weis JJ, Höök M. Resistance to Lyme disease in decorin-deficient mice. The Journal of Clinical Investigation. 107: 845-52. PMID 11285303 DOI: 10.1172/Jci11692  1
2000 Häkkinen L, Strassburger S, Kähäri VM, Scott PG, Eichstetter I, Iozzo RV, Larjava H. A role for decorin in the structural organization of periodontal ligament Laboratory Investigation. 80: 1869-1880. PMID 11140699 DOI: 10.1038/labinvest.3780197  1
2000 Csordás G, Santra M, Reed CC, Eichstetter I, McQuillan DJ, Gross D, Nugent MA, Hajnóczky G, Iozzo RV. Sustained down-regulation of the epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo. The Journal of Biological Chemistry. 275: 32879-87. PMID 10913155 DOI: 10.1074/Jbc.M005609200  1
2000 Nugent MA, Nugent HM, Iozzo RV, Sanchack K, Edelman ER. Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasia. Proceedings of the National Academy of Sciences of the United States of America. 97: 6722-7. PMID 10841569 DOI: 10.1073/Pnas.97.12.6722  0.01
2000 Keene DR, San Antonio JD, Mayne R, McQuillan DJ, Sarris G, Santoro SA, Iozzo RV. Decorin binds near the C terminus of type I collagen. The Journal of Biological Chemistry. 275: 21801-4. PMID 10823816 DOI: 10.1074/Jbc.C000278200  1
2000 Fuki IV, Iozzo RV, Williams KJ. Perlecan heparan sulfate proteoglycan: a novel receptor that mediates a distinct pathway for ligand catabolism. The Journal of Biological Chemistry. 275: 25742-50. PMID 10818109 DOI: 10.1074/Jbc.M909173199  1
2000 Nugent MA, Iozzo RV. Fibroblast growth factor-2 International Journal of Biochemistry and Cell Biology. 32: 115-120. PMID 10687947 DOI: 10.1016/S1357-2725(99)00123-5  1
1999 Iozzo RV. The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins. Journal of Biological Chemistry. 274: 18843-18846. PMID 10383378 DOI: 10.1074/Jbc.274.27.18843  0.01
1999 Iozzo RV, Chakrani F, Perrotti D, McQuillan DJ, Skorski T, Calabretta B, Eichstetter I. Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 96: 3092-7. PMID 10077642 DOI: 10.1073/Pnas.96.6.3092  1
1999 Iozzo RV, Moscatello DK, McQuillan DJ, Eichstetter I. Decorin Is a Biological Ligand for the Epidermal Growth Factor Receptor Journal of Biological Chemistry. 274: 4489-4492. PMID 9988678 DOI: 10.1074/Jbc.274.8.4489  1
1998 Iozzo RV, Danielson KG. Transcriptional and Posttranscriptional Regulation of Proteoglycan Gene Expression Progress in Nucleic Acid Research and Molecular Biology. 62: 19-53. PMID 9932451 DOI: 10.1016/S0079-6603(08)60504-8  0.01
1998 Fleischmajer R, Perlish JS, MacDonald ED, Schechter A, Murdoch AD, Iozzo RV, Yamada Y. There is binding of collagen IV to beta 1 integrin during early skin basement membrane assembly. Annals of the New York Academy of Sciences. 857: 212-27. PMID 9917843 DOI: 10.1111/J.1749-6632.1998.Tb10118.X  0.01
1998 Sharma B, Handler M, Eichstetter I, Whitelock JM, Nugent MA, Iozzo RV. Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo. The Journal of Clinical Investigation. 102: 1599-608. PMID 9788974 DOI: 10.1172/Jci3793  1
1998 Iozzo RV. Matrix Proteoglycans: From Molecular Design to Cellular Function Annual Review of Biochemistry. 67: 609-652. PMID 9759499 DOI: 10.1146/Annurev.Biochem.67.1.609  0.01
1998 Kovalszky I, Dudás J, Oláh-Nagy J, Pogány G, Töváry J, Timár J, Kopper L, Jeney A, Iozzo RV. Inhibition of DNA topoisomerase I activity by heparan sulfate and modulation by basic fibroblast growth factor. Molecular and Cellular Biochemistry. 183: 11-23. PMID 9655174 DOI: 10.1023/A:1006898920637  0.01
1998 Kyriakides TR, Zhu YH, Smith LT, Bain SD, Yang Z, Lin MT, Danielson KG, Iozzo RV, LaMarca M, McKinney CE, Ginns EI, Bornstein P. Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis Journal of Cell Biology. 140: 419-430. PMID 9442117 DOI: 10.1083/Jcb.140.2.419  1
1998 Moscatello DK, Santra M, Mann DM, McQuillan DJ, Wong AJ, Iozzo RV. Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor. The Journal of Clinical Investigation. 101: 406-12. PMID 9435313 DOI: 10.1172/Jci846  1
1997 Kovalszky, Nagy JO, Gallai M, Sebestyén A, Schaff Z, Paku S, Jeney A, Iozzo RV. Altered Proteoglycan Gene Expression in Human Biliary Cirrhosis. Pathology Oncology Research : Por. 3: 51-58. PMID 11173626 DOI: 10.1007/Bf02893354  0.01
1997 Handler M, Yurchenco PD, Iozzo RV. Developmental expression of perlecan during murine embryogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 210: 130-45. PMID 9337134 DOI: 10.1002/(Sici)1097-0177(199710)210:2<130::Aid-Aja6>3.0.Co;2-H  0.01
1997 Fuki IV, Kuhn KM, Lomazov IR, Rothman VL, Tuszynski GP, Iozzo RV, Swenson TL, Fisher EA, Williams KJ. The syndecan family of proteoglycans. Novel receptors mediating internalization of atherogenic lipoproteins in vitro. The Journal of Clinical Investigation. 100: 1611-22. PMID 9294130 DOI: 10.1172/Jci119685  1
1997 Santra M, Mann DM, Mercer EW, Skorski T, Calabretta B, Iozzo RV. Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases. The Journal of Clinical Investigation. 100: 149-57. PMID 9202067 DOI: 10.1172/Jci119507  0.01
1997 Iozzo RV. The family of the small leucine-rich proteoglycans: key regulators of matrix assembly and cellular growth. Critical Reviews in Biochemistry and Molecular Biology. 32: 141-174. PMID 9145286 DOI: 10.3109/10409239709108551  0.01
1997 DeRocco SE, Iozzo R, Ma XP, Schwarting R, Peterson D, Calabretta B. Ectopic expression of A-myb in transgenic mice causes follicular hyperplasia and enhanced B lymphocyte proliferation. Proceedings of the National Academy of Sciences of the United States of America. 94: 3240-4. PMID 9096377 DOI: 10.1073/Pnas.94.7.3240  1
1997 Iozzo RV, Pillarisetti J, Sharma B, Murdoch AD, Danielson KG, Uitto J, Mauviel A. Structural and Functional Characterization of the Human Perlecan Gene Promoter TRANSCRIPTIONAL ACTIVATION BY TRANSFORMING GROWTH FACTOR-β VIA A NUCLEAR FACTOR 1-BINDING ELEMENT Journal of Biological Chemistry. 272: 5219-5228. PMID 9030592 DOI: 10.1074/Jbc.272.8.5219  0.01
1997 Keene DR, Ridgway CC, Iozzo RV. Ultrastructural Evidence for Proteoglycans Mediating an Attachment of Type VI Collagen to Banded Collagen Fibrils Microscopy and Microanalysis. 3: 153-154. DOI: 10.1017/S1431927600007650  1
1996 Iozzo RV, Murdoch AD. Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function. The Faseb Journal. 10: 598-614. DOI: 10.1096/Fasebj.10.5.8621059  0.01
1995 Wegrowski Y, Pillarisetti J, Danielson KG, Suzuki S, Iozzo RV. The murine biglycan: complete cDNA cloning, genomic organization, promoter function, and expression. Genomics. 30: 8-17. PMID 8595907 DOI: 10.1006/Geno.1995.0002  0.01
1995 Danielson KG, Pillarisetti J, Cohen IR, Sholehvar B, Huebner K, Ng LJ, Nicholls JM, Cheah KSE, Iozzo RV. Characterization of the complete genomic structure of the human WNT-5A gene, functional analysis of its promoter, chromosomal mapping, and expression in early human embryogenesis Journal of Biological Chemistry. 270: 31225-31234. PMID 8537388 DOI: 10.1074/Jbc.270.52.31225  1
1995 Naso MF, Morgan JL, Buchberg AM, Siracusa LD, Iozzo RV. Expression pattern and mapping of the murine versican gene (Cspg2) to chromosome 13. Genomics. 29: 297-300. PMID 8530092 DOI: 10.1006/Geno.1995.1251  1
1994 Reginato AM, Iozzo RV, Jimenez SA. Formation of nodular structures resembling mature articular cartilage in long-term primary cultures of human fetal epiphyseal chondrocytes on a hydrogel substrate. Arthritis and Rheumatism. 37: 1338-49. PMID 7945499 DOI: 10.1002/Art.1780370912  1
1994 Iozzo RV. Perlecan: A gem of a proteoglycan Matrix Biology. 14: 203-208. PMID 7921536 DOI: 10.1016/0945-053X(94)90183-X  0.01
1994 Rudnicka L, Varga J, Christiano AM, Iozzo RV, Jimenez SA, Uitto J. Elevated expression of type VII collagen in the skin of patients with systemic sclerosis. Regulation by transforming growth factor-beta. The Journal of Clinical Investigation. 93: 1709-15. PMID 7512991 DOI: 10.1172/Jci117154  0.01
1994 Murdoch AD, Liu B, Schwarting R, Tuan RS, Iozzo RV. Widespread expression of perlecan proteoglycan in basement membranes and extracellular matrices of human tissues as detected by a novel monoclonal antibody against Domain III and by in situ hybridization Journal of Histochemistry and Cytochemistry. 42: 239-249. PMID 7507142 DOI: 10.1177/42.2.7507142  1
1993 Danielson KG, Fazzio A, Cohen I, Cannizzaro LA, Eichstetter I, Iozzo RV. The Human Decorin Gene: Intron-Exon Organization, Discovery of Two Alternatively Spliced Exons in the 5′ Untranslated Region, and Mapping of the Gene to Chromosome 12q23 Genomics. 15: 146-160. PMID 8432526 DOI: 10.1006/Geno.1993.1022  0.01
1992 Alvarez RJ, Sun MJ, Haverty TP, Iozzo RV, Myers JC, Neilson EG. Biosynthetic and proliferative characteristics of tubulointerstitial fibroblasts probed with paracrine cytokines. Kidney International. 41: 14-23. PMID 1593850 DOI: 10.1038/Ki.1992.3  1
1992 Ryynänen M, Ryynänen J, Sollberg S, Iozzo RV, Knowlton RG, Uitto J. Genetic linkage of type VII collagen (COL7A1) to dominant dystrophic epidermolysis bullosa in families with abnormal anchoring fibrils. Journal of Clinical Investigation. 89: 974-980. PMID 1347297 DOI: 10.1172/Jci115680  0.01
1990 Iozzo RV, Hacobian N. Myristoylation of heparan sulfate proteoglycan and proteins occurs post-translationally in human colon carcinoma cells Biochemical and Biophysical Research Communications. 172: 905-912. PMID 2241979 DOI: 10.1016/0006-291X(90)90761-B  0.01
1990 Kovalszky I, Pogany G, Molnar G, Jeney A, Lapis K, Karacsonyi S, Szecseny A, Iozzo RV. Altered glycosaminoglycan composition in reactive and neoplastic human liver. Biochemical and Biophysical Research Communications. 167: 883-90. PMID 2157432 DOI: 10.1016/0006-291X(90)90606-N  0.01
1989 Iozzo RV, Sampson PM, Schmitt GK. Neoplastic modulation of extracellular matrix: stimulation of chondroitin sulfate proteoglycan and hyaluronic acid synthesis in co-cultures of human colon carcinoma and smooth muscle cells. Journal of Cellular Biochemistry. 39: 355-78. PMID 2722966 DOI: 10.1002/Jcb.240390403  0.01
1989 Simionescu D, Iozzo RV, Kefalides NA. Bovine pericardial proteoglycan: Biochemical, immunochemical and ultrastructural studies Matrix. 9: 301-310. PMID 2677626 DOI: 10.1016/S0934-8832(89)80006-X  1
1989 Markovitz LJ, Savage EB, Ratcliffe MB, Bavaria JE, Kreiner G, Iozzo RV, Hargrove WC, Bogen DK, Edmunds LH. Large animal model of left ventricular aneurysm. The Annals of Thoracic Surgery. 48: 838-45. PMID 2596920 DOI: 10.1016/0003-4975(89)90682-6  1
1989 Iozzo RV, Hassell JR. Identification of the precursor protein for the heparan sulfate proteoglycan of human colon carcinoma cells and its post-translational modifications. Archives of Biochemistry and Biophysics. 269: 239-249. PMID 2521785 DOI: 10.1016/0003-9861(89)90105-7  0.01
1986 Iozzo RV, Pacifici M. Ultrastructural localization of the major proteoglycan and type II procollagen in organelles and extracellular matrix of cultured chondroblasts Histochemistry. 86: 113-122. PMID 3818355 DOI: 10.1007/Bf00493375  1
1986 Greene RA, Bloch MJ, Huff DS, Iozzo RV. MURCS association with additional congenital anomalies. Human Pathology. 17: 88-91. PMID 3510965 DOI: 10.1016/S0046-8177(86)80160-5  0.01
1986 Iozzo RV, Ketterer CL, Slaymaker DJ. Evidence of a small hydrophobic domain in the core protein of the heparan sulfate proteoglycan from human colon carcinoma cells. Febs Letters. 206: 304-8. PMID 2944764 DOI: 10.1016/0014-5793(86)81001-8  0.01
1985 Miller JE, Whitman GJ, Iozzo RV, Jacobs DO, Ziegler MM. Early diagnosis of experimental necrotizing enterocolitis using proton nuclear magnetic resonance. The Journal of Surgical Research. 39: 322-30. PMID 3876481 DOI: 10.1016/0022-4804(85)90110-6  1
1979 Ruff RL, Shaw CM, Beckwith JB, Iozzo RV. Cerebral infarction complicating umbilical vein catheterization. Annals of Neurology. 6: 85. PMID 507766 DOI: 10.1002/Ana.410060125  1
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