| Year |
Citation |
Score |
| 2018 |
Chen F, Coslo DM, Chen T, Zhang L, Tian Y, Smith PB, Patterson AD, Omiecinski CJ. Metabolomic approaches reveal the role of CAR in energy metabolism. Journal of Proteome Research. PMID 30336042 DOI: 10.1021/Acs.Jproteome.8B00566 |
0.365 |
|
| 2018 |
Niu B, Coslo DM, Bataille AR, Albert I, Pugh BF, Omiecinski CJ. In vivo genome-wide binding interactions of mouse and human constitutive androstane receptors reveal novel gene targets. Nucleic Acids Research. PMID 30102401 DOI: 10.1093/Nar/Gky692 |
0.453 |
|
| 2016 |
Laurenzana EM, Coslo DM, Vigilar MV, Roman AM, Omiecinski CJ. Activation of the Constitutive Androstane Receptor by Monophthalates. Chemical Research in Toxicology. PMID 27551952 DOI: 10.1021/Acs.Chemrestox.6B00186 |
0.441 |
|
| 2016 |
Girer NG, Murray IA, Omiecinski CJ, Perdew GH. Hepatic Aryl Hydrocarbon Receptor Attenuates Fibroblast Growth Factor 21 Expression. The Journal of Biological Chemistry. PMID 27226639 DOI: 10.1074/Jbc.M116.715151 |
0.467 |
|
| 2016 |
Hao R, Su S, Wan Y, Shen F, Niu B, Coslo D, Albert I, Han X, Omiecinski CJ. Bioinformatic Analysis of MicroRNA Networks Following the Activation of the Constitutive Androstane Receptor (CAR) in Mouse Liver. Biochimica Et Biophysica Acta. PMID 27080131 DOI: 10.1016/J.Bbagrm.2016.04.002 |
0.432 |
|
| 2014 |
Takeda S, Ikeda E, Su S, Harada M, Okazaki H, Yoshioka Y, Nishimura H, Ishii H, Kakizoe K, Taniguchi A, Tokuyasu M, Himeno T, Watanabe K, Omiecinski CJ, Aramaki H. Δ(9)-THC modulation of fatty acid 2-hydroxylase (FA2H) gene expression: possible involvement of induced levels of PPARα in MDA-MB-231 breast cancer cells. Toxicology. 326: 18-24. PMID 25291031 DOI: 10.1016/J.Tox.2014.09.011 |
0.414 |
|
| 2014 |
Wahlang B, Falkner KC, Clair HB, Al-Eryani L, Prough RA, States JC, Coslo DM, Omiecinski CJ, Cave MC. Human receptor activation by aroclor 1260, a polychlorinated biphenyl mixture. Toxicological Sciences : An Official Journal of the Society of Toxicology. 140: 283-97. PMID 24812009 DOI: 10.1093/Toxsci/Kfu083 |
0.416 |
|
| 2014 |
Su S, Yang X, Omiecinski CJ. Intronic DNA elements regulate Nrf2 chemical responsiveness of the human microsomal epoxide hydrolase gene (EPHX1) through a far upstream alternative promoter. Biochimica Et Biophysica Acta. 1839: 493-505. PMID 24704207 DOI: 10.1016/J.Bbagrm.2014.03.014 |
0.463 |
|
| 2014 |
Currie RA, Peffer RC, Goetz AK, Omiecinski CJ, Goodman JI. Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action. Toxicology. 321: 80-8. PMID 24675475 DOI: 10.1016/J.Tox.2014.03.003 |
0.367 |
|
| 2014 |
Su S, Omiecinski CJ. Sp1 and Sp3 transcription factors regulate the basal expression of human microsomal epoxide hydrolase (EPHX1) through interaction with the E1b far upstream promoter. Gene. 536: 135-44. PMID 24315822 DOI: 10.1016/J.Gene.2013.11.053 |
0.356 |
|
| 2014 |
Chen T, Laurenzana EM, Coslo DM, Chen F, Omiecinski CJ. Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor. The Biochemical Journal. 458: 95-107. PMID 24224465 DOI: 10.1042/Bj20130685 |
0.417 |
|
| 2014 |
Elcombe CR, Peffer RC, Wolf DC, Bailey J, Bars R, Bell D, Cattley RC, Ferguson SS, Geter D, Goetz A, Goodman JI, Hester S, Jacobs A, Omiecinski CJ, Schoeny R, et al. Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator. Critical Reviews in Toxicology. 44: 64-82. PMID 24180433 DOI: 10.3109/10408444.2013.835786 |
0.45 |
|
| 2013 |
Chen F, Zamule SM, Coslo DM, Chen T, Omiecinski CJ. The human constitutive androstane receptor promotes the differentiation and maturation of hepatic-like cells. Developmental Biology. 384: 155-65. PMID 24144921 DOI: 10.1016/J.Ydbio.2013.10.012 |
0.782 |
|
| 2013 |
Takeda S, Yoshida K, Nishimura H, Harada M, Okajima S, Miyoshi H, Okamoto Y, Amamoto T, Watanabe K, Omiecinski CJ, Aramaki H. Δ(9)-Tetrahydrocannabinol disrupts estrogen-signaling through up-regulation of estrogen receptor β (ERβ). Chemical Research in Toxicology. 26: 1073-9. PMID 23718638 DOI: 10.1021/Tx4000446 |
0.343 |
|
| 2013 |
Nguyen HL, Yang X, Omiecinski CJ. Expression of a novel mRNA transcript for human microsomal epoxide hydrolase (EPHX1) is regulated by short open reading frames within its 5'-untranslated region. Rna (New York, N.Y.). 19: 752-66. PMID 23564882 DOI: 10.1261/Rna.037036.112 |
0.389 |
|
| 2013 |
Takeda S, Harada M, Su S, Okajima S, Miyoshi H, Yoshida K, Nishimura H, Okamoto Y, Amamoto T, Watanabe K, Omiecinski CJ, Aramaki H. Induction of the fatty acid 2-hydroxylase (FA2H) gene by Δ(9)-tetrahydrocannabinol in human breast cancer cells. The Journal of Toxicological Sciences. 38: 305-8. PMID 23535410 DOI: 10.2131/Jts.38.305 |
0.384 |
|
| 2013 |
Takeda S, Noguchi M, Matsuo K, Yamaguchi Y, Kudo T, Nishimura H, Okamoto Y, Amamoto T, Shindo M, Omiecinski CJ, Aramaki H. (-)-Xanthatin up-regulation of the GADD45γ tumor suppressor gene in MDA-MB-231 breast cancer cells: role of topoisomerase IIα inhibition and reactive oxygen species. Toxicology. 305: 1-9. PMID 23313378 DOI: 10.1016/J.Tox.2012.12.019 |
0.369 |
|
| 2012 |
Laurenzana EM, Chen T, Kannuswamy M, Sell BE, Strom SC, Li Y, Omiecinski CJ. The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3). Molecular Pharmacology. 82: 918-28. PMID 22896671 DOI: 10.1124/Mol.112.080721 |
0.454 |
|
| 2011 |
Omiecinski CJ, Coslo DM, Chen T, Laurenzana EM, Peffer RC. Multi-species analyses of direct activators of the constitutive androstane receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 123: 550-62. PMID 21778469 DOI: 10.1093/Toxsci/Kfr191 |
0.39 |
|
| 2011 |
Takeda S, Matsuo K, Yaji K, Okajima-Miyazaki S, Harada M, Miyoshi H, Okamoto Y, Amamoto T, Shindo M, Omiecinski CJ, Aramaki H. (--)-Xanthatin selectively induces GADD45γ and stimulates caspase-independent cell death in human breast cancer MDA-MB-231 cells. Chemical Research in Toxicology. 24: 855-65. PMID 21568272 DOI: 10.1021/Tx200046S |
0.316 |
|
| 2011 |
Zamule SM, Coslo DM, Chen F, Omiecinski CJ. Differentiation of human embryonic stem cells along a hepatic lineage. Chemico-Biological Interactions. 190: 62-72. PMID 21241686 DOI: 10.1016/J.Cbi.2011.01.009 |
0.761 |
|
| 2011 |
DeKeyser JG, Laurenzana EM, Peterson EC, Chen T, Omiecinski CJ. Selective phthalate activation of naturally occurring human constitutive androstane receptor splice variants and the pregnane X receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: 381-91. PMID 21227907 DOI: 10.1093/Toxsci/Kfq394 |
0.449 |
|
| 2011 |
Omiecinski CJ, Vanden Heuvel JP, Perdew GH, Peters JM. Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicities. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: S49-75. PMID 21059794 DOI: 10.1093/Toxsci/Kfq338 |
0.349 |
|
| 2010 |
DiNatale BC, Murray IA, Schroeder JC, Flaveny CA, Lahoti TS, Laurenzana EM, Omiecinski CJ, Perdew GH. Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling. Toxicological Sciences : An Official Journal of the Society of Toxicology. 115: 89-97. PMID 20106948 DOI: 10.1093/Toxsci/Kfq024 |
0.378 |
|
| 2010 |
Schroeder JC, Dinatale BC, Murray IA, Flaveny CA, Liu Q, Laurenzana EM, Lin JM, Strom SC, Omiecinski CJ, Amin S, Perdew GH. The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor. Biochemistry. 49: 393-400. PMID 20000589 DOI: 10.1021/Bi901786X |
0.428 |
|
| 2009 |
Moody DE, Fang WB, Lin SN, Weyant DM, Strom SC, Omiecinski CJ. Effect of rifampin and nelfinavir on the metabolism of methadone and buprenorphine in primary cultures of human hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 2323-9. PMID 19773542 DOI: 10.1124/Dmd.109.028605 |
0.37 |
|
| 2009 |
Yang X, Liang SH, Weyant DM, Lazarus P, Gallagher CJ, Omiecinski CJ. The expression of human microsomal epoxide hydrolase is predominantly driven by a genetically polymorphic far upstream promoter. The Journal of Pharmacology and Experimental Therapeutics. 330: 23-30. PMID 19364907 DOI: 10.1124/Jpet.109.150870 |
0.402 |
|
| 2009 |
DeKeyser JG, Stagliano MC, Auerbach SS, Prabhu KS, Jones AD, Omiecinski CJ. Di(2-ethylhexyl) phthalate is a highly potent agonist for the human constitutive androstane receptor splice variant CAR2. Molecular Pharmacology. 75: 1005-13. PMID 19211671 DOI: 10.1124/Mol.108.053702 |
0.524 |
|
| 2008 |
Goyak KM, Johnson MC, Strom SC, Omiecinski CJ. Expression profiling of interindividual variability following xenobiotic exposures in primary human hepatocyte cultures. Toxicology and Applied Pharmacology. 231: 216-24. PMID 18559280 DOI: 10.1016/J.Taap.2008.04.024 |
0.756 |
|
| 2008 |
Zamule SM, Strom SC, Omiecinski CJ. Preservation of hepatic phenotype in lentiviral-transduced primary human hepatocytes. Chemico-Biological Interactions. 173: 179-86. PMID 18468591 DOI: 10.1016/J.Cbi.2008.03.015 |
0.774 |
|
| 2008 |
Bogen KT, Benson JM, Yost GS, Morris JB, Dahl AR, Clewell HJ, Krishnan K, Omiecinski CJ. Naphthalene metabolism in relation to target tissue anatomy, physiology, cytotoxicity and tumorigenic mechanism of action. Regulatory Toxicology and Pharmacology : Rtp. 51: S27-36. PMID 18191315 DOI: 10.1016/J.Yrtph.2007.10.018 |
0.322 |
|
| 2007 |
Page JL, Strom SC, Omiecinski CJ. Regulation of the human cathepsin E gene by the constitutive androstane receptor. Archives of Biochemistry and Biophysics. 467: 132-8. PMID 17888866 DOI: 10.1016/J.Abb.2007.08.001 |
0.491 |
|
| 2007 |
Patel RD, Hollingshead BD, Omiecinski CJ, Perdew GH. Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver. Hepatology (Baltimore, Md.). 46: 209-18. PMID 17596880 DOI: 10.1002/Hep.21671 |
0.469 |
|
| 2007 |
Olsavsky KM, Page JL, Johnson MC, Zarbl H, Strom SC, Omiecinski CJ. Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues. Toxicology and Applied Pharmacology. 222: 42-56. PMID 17512962 DOI: 10.1016/J.Taap.2007.03.032 |
0.499 |
|
| 2007 |
Stoner MA, Auerbach SS, Zamule SM, Strom SC, Omiecinski CJ. Transactivation of a DR-1 PPRE by a human constitutive androstane receptor variant expressed from internal protein translation start sites. Nucleic Acids Research. 35: 2177-90. PMID 17355985 DOI: 10.1093/Nar/Gkm090 |
0.751 |
|
| 2007 |
Page JL, Johnson MC, Olsavsky KM, Strom SC, Zarbl H, Omiecinski CJ. Gene expression profiling of extracellular matrix as an effector of human hepatocyte phenotype in primary cell culture. Toxicological Sciences : An Official Journal of the Society of Toxicology. 97: 384-97. PMID 17329237 DOI: 10.1093/Toxsci/Kfm034 |
0.48 |
|
| 2007 |
Auerbach SS, Dekeyser JG, Stoner MA, Omiecinski CJ. CAR2 displays unique ligand binding and RXRalpha heterodimerization characteristics. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 428-39. PMID 17194715 DOI: 10.1124/Dmd.106.012641 |
0.402 |
|
| 2007 |
Faucette SR, Zhang TC, Moore R, Sueyoshi T, Omiecinski CJ, LeCluyse EL, Negishi M, Wang H. Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers. The Journal of Pharmacology and Experimental Therapeutics. 320: 72-80. PMID 17041008 DOI: 10.1124/Jpet.106.112136 |
0.49 |
|
| 2007 |
Zamule SM, Strom SC, Omiecinski CJ. High efficiency transduction and stable gene expression of primary human hepatocytes with lentiviral vectors The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A442 |
0.754 |
|
| 2007 |
Su S, Omiecinski CJ. Differential splicing of the human peroxisome proliferator‐activated receptor, PPARβ/δ The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A419-D |
0.394 |
|
| 2005 |
Auerbach SS, Stoner MA, Su S, Omiecinski CJ. Retinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3). Molecular Pharmacology. 68: 1239-53. PMID 16099843 DOI: 10.1124/Mol.105.013417 |
0.436 |
|
| 2005 |
Abdel-Rahman SZ, Ammenheuser MM, Omiecinski CJ, Wickliffe JK, Rosenblatt JI, Ward JB. Variability in human sensitivity to 1,3-butadiene: influence of polymorphisms in the 5'-flanking region of the microsomal epoxide hydrolase gene (EPHX1). Toxicological Sciences : An Official Journal of the Society of Toxicology. 85: 624-31. PMID 15716486 DOI: 10.1093/Toxsci/Kfi115 |
0.323 |
|
| 2005 |
Liang SH, Hassett C, Omiecinski CJ. Alternative promoters determine tissue-specific expression profiles of the human microsomal epoxide hydrolase gene (EPHX1). Molecular Pharmacology. 67: 220-30. PMID 15465926 DOI: 10.1124/Mol.104.005579 |
0.449 |
|
| 2004 |
Hosagrahara VP, Rettie AE, Hassett C, Omiecinski CJ. Functional analysis of human microsomal epoxide hydrolase genetic variants. Chemico-Biological Interactions. 150: 149-59. PMID 15535985 DOI: 10.1016/J.Cbi.2004.07.004 |
0.408 |
|
| 2004 |
Yamamoto M, Mise M, Matsumoto S, Ito S, Gohyama N, Ishida S, Sagara Y, Omiecinski CJ, Oguri K, Yamada H. Comparison of genomic and cDNA sequences of guinea pig CYP2B18 and rat CYP2B2: absence of a phenobarbital-responsive enhancer module in the upstream region of the CYP2B18 gene. Journal of Biochemical and Molecular Toxicology. 18: 124-30. PMID 15252867 DOI: 10.1002/Jbt.20016 |
0.391 |
|
| 2004 |
Sidhu JS, Liu F, Omiecinski CJ. Phenobarbital responsiveness as a uniquely sensitive indicator of hepatocyte differentiation status: requirement of dexamethasone and extracellular matrix in establishing the functional integrity of cultured primary rat hepatocytes. Experimental Cell Research. 292: 252-64. PMID 14697333 DOI: 10.1016/J.Yexcr.2003.09.001 |
0.456 |
|
| 2003 |
Auerbach SS, Ramsden R, Stoner MA, Verlinde C, Hassett C, Omiecinski CJ. Alternatively spliced isoforms of the human constitutive androstane receptor. Nucleic Acids Research. 31: 3194-207. PMID 12799447 DOI: 10.1093/Nar/Gkg419 |
0.485 |
|
| 2001 |
Sidhu JS, Liu F, Omiecinski CJ. Requirement of Ecm and Insulin For Maintenance of Liver-Specific Functions and Cell Survival in Primary Rat Hepatocytes. Thescientificworldjournal. 1: 98. PMID 30147576 DOI: 10.1100/Tsw.2001.198 |
0.435 |
|
| 2001 |
Sidhu JS, Liu F, Boyle SM, Omiecinski CJ. PI3K inhibitors reverse the suppressive actions of insulin on CYP2E1 expression by activating stress-response pathways in primary rat hepatocytes. Molecular Pharmacology. 59: 1138-46. PMID 11306697 DOI: 10.1124/Mol.59.5.1138 |
0.328 |
|
| 2000 |
Beck NB, Sidhu JS, Omiecinski CJ. Baculovirus vectors repress phenobarbital-mediated gene induction and stimulate cytokine expression in primary cultures of rat hepatocytes. Gene Therapy. 7: 1274-83. PMID 10918498 DOI: 10.1038/Sj.Gt.3301246 |
0.416 |
|
| 2000 |
Sandberg M, Hassett C, Adman ET, Meijer J, Omiecinski CJ. Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms. The Journal of Biological Chemistry. 275: 28873-81. PMID 10862610 DOI: 10.1074/Jbc.M001153200 |
0.394 |
|
| 2000 |
Krovat BC, Tracy JH, Omiecinski CJ. Fingerprinting of cytochrome P450 and microsomal epoxide hydrolase gene expression in human blood cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 55: 352-60. PMID 10828267 DOI: 10.1093/Toxsci/55.2.352 |
0.468 |
|
| 2000 |
Omiecinski CJ, Hassett C, Hosagrahara V. Epoxide hydrolase--polymorphism and role in toxicology. Toxicology Letters. 365-70. PMID 10720753 DOI: 10.1016/S0378-4274(99)00235-0 |
0.361 |
|
| 1999 |
Beck NB, Omiecinski CJ. Lack of modulation by phenobarbital of cyclic AMP levels or protein kinase A activity in rat primary hepatocytes. Biochemical Pharmacology. 58: 1109-14. PMID 10484068 DOI: 10.1016/S0006-2952(99)00189-6 |
0.362 |
|
| 1999 |
Hulla JE, Miller MS, Taylor JA, Hein DW, Furlong CE, Omiecinski CJ, Kunkel TA. Symposium overview: The role of genetic polymorphism and repair deficiencies in environmental disease Toxicological Sciences. 47: 135-143. PMID 10220849 DOI: 10.1093/Toxsci/47.2.135 |
0.328 |
|
| 1999 |
Ramsden R, Beck NB, Sommer KM, Omiecinski CJ. Phenobarbital responsiveness conferred by the 5'-flanking region of the rat CYP2B2 gene in transgenic mice. Gene. 228: 169-79. PMID 10072770 DOI: 10.1016/S0378-1119(98)00612-X |
0.345 |
|
| 1999 |
Laurenzana EM, Hassett C, Omiecinski CJ. Post-transcriptional regulation of human microsomal epoxide hydrolase. Pharmacogenetics. 8: 157-67. PMID 10022753 DOI: 10.1097/00008571-199804000-00008 |
0.375 |
|
| 1999 |
Sidhu JS, Omiecinski CJ. Insulin-mediated modulation of cytochrome P450 gene induction profiles in primary rat hepatocyte cultures. Journal of Biochemical and Molecular Toxicology. 13: 1-9. PMID 9890442 DOI: 10.1002/(Sici)1099-0461(1999)13:1<1::Aid-Jbt1>3.0.Co;2-2 |
0.387 |
|
| 1998 |
Sidhu JS, Marcus CB, Parkinson A, Omiecinski CJ. Differential induction of cytochrome P450 gene expression by 4n-alkyl-methylenedioxybenzenes in primary rat hepatocyte cultures. Journal of Biochemical and Molecular Toxicology. 12: 253-62. PMID 9664231 DOI: 10.1002/(Sici)1099-0461(1998)12:5<253::Aid-Jbt1>3.0.Co;2-K |
0.463 |
|
| 1998 |
Hassett C, Laurenzana EM, Sidhu JS, Omiecinski CJ. Effects of chemical inducers on human microsomal epoxide hydrolase in primary hepatocyte cultures. Biochemical Pharmacology. 55: 1059-69. PMID 9605429 DOI: 10.1016/S0006-2952(97)00679-5 |
0.449 |
|
| 1998 |
Andersen MR, Farin FM, Omiecinski CJ. Quantification of multiple human cytochrome P450 mRNA molecules using competitive reverse transcriptase-PCR. Dna and Cell Biology. 17: 231-8. PMID 9539103 DOI: 10.1089/Dna.1998.17.231 |
0.415 |
|
| 1998 |
Sidhu JS, Omiecinski CJ. Protein synthesis inhibitors exhibit a nonspecific effect on phenobarbital-inducible cytochome P450 gene expression in primary rat hepatocytes. The Journal of Biological Chemistry. 273: 4769-75. PMID 9468541 DOI: 10.1074/Jbc.273.8.4769 |
0.352 |
|
| 1997 |
Hassett C, Lin J, Carty CL, Laurenzana EM, Omiecinski CJ. Human hepatic microsomal epoxide hydrolase: comparative analysis of polymorphic expression. Archives of Biochemistry and Biophysics. 337: 275-83. PMID 9016823 DOI: 10.1006/Abbi.1996.9794 |
0.426 |
|
| 1997 |
Sommer KM, Ramsden R, Sidhu J, Costa P, Omiecinski CJ. Promoter region analysis of the rat CYP2B1 and CYP2B2 genes. Pharmacogenetics. 6: 369-74. PMID 8873225 DOI: 10.1097/00008571-199608000-00012 |
0.303 |
|
| 1996 |
Heinonen JT, Sidhu JS, Reilly MT, Farin FM, Omiecinski CJ, Eaton DL, Kavanagh TJ. Assessment of regional cytochrome P450 activities in rat liver slices using resorufin substrates and fluorescence confocal laser cytometry Environmental Health Perspectives. 104: 536-543. PMID 8743442 DOI: 10.1289/Ehp.96104536 |
0.354 |
|
| 1995 |
Farin FM, Bigler LG, Oda D, McDougall JK, Omiecinski CJ. Expression of cytochrome P450 and microsomal epoxide hydrolase in cervical and oral epithelial cells immortalized by human papillomavirus type 16 E6/E7 genes. Carcinogenesis. 16: 1391-401. PMID 7788860 DOI: 10.1093/Carcin/16.6.1391 |
0.367 |
|
| 1995 |
Sidhu JS, Omiecinski CJ. Modulation of xenobiotic-inducible cytochrome P450 gene expression by dexamethasone in primary rat hepatocytes. Pharmacogenetics. 5: 24-36. PMID 7773300 DOI: 10.1097/00008571-199502000-00003 |
0.475 |
|
| 1995 |
Sidhu JS, Omiecinski CJ. cAMP-associated inhibition of phenobarbital-inducible cytochrome P450 gene expression in primary rat hepatocyte cultures. The Journal of Biological Chemistry. 270: 12762-73. PMID 7759530 DOI: 10.1074/Jbc.270.21.12762 |
0.421 |
|
| 1995 |
Richardson TH, Jung F, Griffin KJ, Wester M, Raucy JL, Kemper B, Bornheim LM, Hassett C, Omiecinski CJ, Johnson EF. A universal approach to the expression of human and rabbit cytochrome P450s of the 2C subfamily in Escherichia coli Archives of Biochemistry and Biophysics. 323: 87-96. PMID 7487078 DOI: 10.1006/Abbi.1995.0013 |
0.303 |
|
| 1994 |
Hassett C, Robinson KB, Beck NB, Omiecinski CJ. The human microsomal epoxide hydrolase gene (EPHX1): complete nucleotide sequence and structural characterization. Genomics. 23: 433-42. PMID 7835893 DOI: 10.1006/Geno.1994.1520 |
0.4 |
|
| 1994 |
Nims RW, Sidhu JS, Thomas PE, Mellini DW, Nelson VC, Omiecinski CJ, Lubet RA. Absence of enantioselectivity in the pharmacodynamics of P450 2B induction by 5-ethyl-5-phenylhydantoin in the male rat liver or in cultured rat hepatocytes Journal of Biochemical Toxicology. 9: 279-288. PMID 7534352 DOI: 10.1002/Jbt.2570090602 |
0.371 |
|
| 1994 |
Hassett C, Aicher L, Sidhu JS, Omiecinski CJ. Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants. Human Molecular Genetics. 3: 421-8. PMID 7516776 DOI: 10.1093/Hmg/3.3.421 |
0.388 |
|
| 1994 |
Farin FM, Pohlman TH, Omiecinski CJ. Expression of cytochrome P450s and microsomal epoxide hydrolase in primary cultures of human umbilical vein endothelial cells. Toxicology and Applied Pharmacology. 124: 1-9. PMID 7507267 DOI: 10.1006/Taap.1994.1001 |
0.425 |
|
| 1993 |
Sidhu JS, Farin FM, Omiecinski CJ. Influence of extracellular matrix overlay on phenobarbital-mediated induction of CYP2B1, 2B2, and 3A1 genes in primary adult rat hepatocyte culture. Archives of Biochemistry and Biophysics. 301: 103-13. PMID 8442654 DOI: 10.1006/Abbi.1993.1121 |
0.412 |
|
| 1993 |
Furlong CE, Costa LG, Hassett C, Richter RJ, Sundstrom JA, Adler DA, Disteche CM, Omiecinski CJ, Chapline C, Crabb JW. Human and rabbit paraoxonases: purification, cloning, sequencing, mapping and role of polymorphism in organophosphate detoxification. Chemico-Biological Interactions. 87: 35-48. PMID 8393745 DOI: 10.1016/0009-2797(93)90023-R |
0.372 |
|
| 1993 |
Omiecinski CJ, Aicher L, Holubkov R, Checkoway H. Human peripheral lymphocytes as indicators of microsomal epoxide hydrolase activity in liver and lung. Pharmacogenetics. 3: 150-8. PMID 8334439 DOI: 10.1097/00008571-199306000-00005 |
0.352 |
|
| 1993 |
Humbert R, Adler DA, Disteche CM, Hassett C, Omiecinski CJ, Furlong CE. The molecular basis of the human serum paraoxonase activity polymorphism. Nature Genetics. 3: 73-6. PMID 8098250 DOI: 10.1038/Ng0193-73 |
0.334 |
|
| 1993 |
Farin FM, Omiecinski CJ. Regiospecific expression of cytochrome P-450s and microsomal epoxide hydrolase in human brain tissue. Journal of Toxicology and Environmental Health. 40: 317-35. PMID 7693960 DOI: 10.1080/15287399309531797 |
0.393 |
|
| 1992 |
Hassett C, Ramsden R, Omiecinski CJ. Isolating cytochrome P450 cDNA and genomic clones: library screening with synthetic DNA oligomers. Methods in Enzymology. 206: 291-301. PMID 1784215 DOI: 10.1016/0076-6879(91)06099-O |
0.341 |
|
| 1992 |
Chen ZY, Farin F, Omiecinski CJ, Eaton DL. Association between growth stimulation by phenobarbital and expression of cytochromes P450 1A1, 1A2, 2B1/2 and 3A1 in hepatic hyperplastic nodules in male F344 rats. Carcinogenesis. 13: 675-82. PMID 1349513 DOI: 10.1093/Carcin/13.4.675 |
0.386 |
|
| 1991 |
Hassett C, Richter RJ, Humbert R, Chapline C, Crabb JW, Omiecinski CJ, Furlong CE. Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence. Biochemistry. 30: 10141-9. PMID 1657140 DOI: 10.1021/Bi00106A010 |
0.37 |
|
| 1990 |
Hassett C, Omiecinski CJ. Sequence and gene expression of rabbit cytochrome P450 IIC16: comparison to highly related family members. Nucleic Acids Research. 18: 1429-34. PMID 2326187 DOI: 10.1093/Nar/18.6.1429 |
0.377 |
|
| 1990 |
Marcus CB, Wilson NM, Jefcoate CR, Wilkinson CF, Omiecinski CJ. Selective induction of cytochrome P450 isozymes in rat liver by 4-n-alkyl-methylenedioxybenzenes. Archives of Biochemistry and Biophysics. 277: 8-16. PMID 2306127 DOI: 10.1016/0003-9861(90)90543-8 |
0.357 |
|
| 1990 |
Marcus CB, Wilson NM, Keith IM, Jefcoate CR, Omiecinski CJ. Selective expression of cytochrome P450 isozymes by 4-n-alkyl-methylenedioxybenzenes in rat lung cells. Archives of Biochemistry and Biophysics. 277: 17-25. PMID 2306118 DOI: 10.1016/0003-9861(90)90544-9 |
0.301 |
|
| 1989 |
Wilson NM, Omiecinski CJ. Xenobiotic microsomal epoxide hydrolase: 5' sequence of the human gene. Biochimica Et Biophysica Acta. 1008: 357-8. PMID 2758034 DOI: 10.1016/0167-4781(89)90029-8 |
0.392 |
|
| 1989 |
Hassett C, Turnblom SM, DeAngeles A, Omiecinski CJ. Rabbit microsomal epoxide hydrolase: isolation and characterization of the xenobiotic metabolizing enzyme cDNA. Archives of Biochemistry and Biophysics. 271: 380-9. PMID 2729997 DOI: 10.1016/0003-9861(89)90287-7 |
0.419 |
|
| 1989 |
Hassett C, Luchtel DL, Omiecinski CJ. Hepatic expression of rat P450 mRNA assessed by in situ hybridization to oligomer probes. Dna (Mary Ann Liebert, Inc.). 8: 29-37. PMID 2707121 DOI: 10.1089/dna.1.1989.8.29 |
0.304 |
|
| 1988 |
Hassett C, Omiecinski CJ. Use of a conserved consensus oligomer in the identification of cytochrome P-450 mRNAs. Biochemical and Biophysical Research Communications. 149: 326-33. PMID 3426576 DOI: 10.1016/0006-291X(87)90370-6 |
0.308 |
|
| 1988 |
Schuetz EG, Li D, Omiecinski CJ, Muller-Eberhard U, Kleinman HK, Elswick B, Guzelian PS. Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix. Journal of Cellular Physiology. 134: 309-23. PMID 3350857 DOI: 10.1002/Jcp.1041340302 |
0.479 |
|
| 1986 |
Omiecinski CJ. Tissue-specific expression of rat mRNAs homologous to cytochromes P-450b and P-450e. Nucleic Acids Research. 14: 1525-39. PMID 3754047 DOI: 10.1093/Nar/14.3.1525 |
0.36 |
|
| 1984 |
Omiecinski CJ, Hines RN, Foldes RL, Levy JB, Bresnick E. Molecular induction by phenobarbital of a rat hepatic form of cytochrome P-450: expression of a 4-kilobase messenger RNA. Archives of Biochemistry and Biophysics. 227: 478-93. PMID 6141764 DOI: 10.1016/0003-9861(83)90478-2 |
0.336 |
|
| 1978 |
Omiecinski CJ, Bond JA, Juchau MR. Stimulation by hematin of monooxygenase activity in extra-hepatic tissues from rats, rabbits and chickens. Biochemical and Biophysical Research Communications. 83: 1004-11. PMID 708418 DOI: 10.1016/0006-291X(78)91495-X |
0.348 |
|
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