Klemens J. Hertel - Publications

University of California, Irvine, Irvine, CA 
Molecular Biology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Aubol BE, Wu G, Keshwani MM, Movassat M, Fattet L, Hertel KJ, Fu XD, Adams JA. Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing. Molecular Cell. PMID 27397683 DOI: 10.1016/J.Molcel.2016.05.034  0.36
2016 Movassat M, Crabb TL, Busch A, Yao C, Reynolds DJ, Shi Y, Hertel KJ. Coupling between alternative polyadenylation and alternative splicing is limited to terminal introns. Rna Biology. 0. PMID 27245359 DOI: 10.1080/15476286.2016.1191727  0.36
2015 Mueller WF, Larsen LS, Garibaldi A, Hatfield GW, Hertel KJ. The Silent Sway of Splicing by Synonymous Substitutions. The Journal of Biological Chemistry. PMID 26424794 DOI: 10.1074/Jbc.M115.684035  0.36
2015 Busch A, Hertel KJ. Splicing predictions reliably classify different types of alternative splicing. Rna (New York, N.Y.). 21: 813-23. PMID 25805853 DOI: 10.1261/Rna.048769.114  0.36
2014 Morris JP, Greer R, Russ HA, von Figura G, Kim GE, Busch A, Lee J, Hertel KJ, Kim S, McManus M, Hebrok M. Dicer regulates differentiation and viability during mouse pancreatic cancer initiation. Plos One. 9: e95486. PMID 24788257 DOI: 10.1371/Journal.Pone.0095486  0.36
2014 von Figura G, Fukuda A, Roy N, Liku ME, Morris Iv JP, Kim GE, Russ HA, Firpo MA, Mulvihill SJ, Dawson DW, Ferrer J, Mueller WF, Busch A, Hertel KJ, Hebrok M. The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma. Nature Cell Biology. 16: 255-67. PMID 24561622 DOI: 10.1038/Ncb2916  0.36
2014 Mueller WF, Hertel KJ. Kinetic analysis of in vitro pre-mRNA splicing in HeLa nuclear extract. Methods in Molecular Biology (Clifton, N.J.). 1126: 161-8. PMID 24549663 DOI: 10.1007/978-1-62703-980-2_12  0.36
2014 Movassat M, Mueller WF, Hertel KJ. In vitro assay of pre-mRNA splicing in mammalian nuclear extract. Methods in Molecular Biology (Clifton, N.J.). 1126: 151-60. PMID 24549662 DOI: 10.1007/978-1-62703-980-2_11  0.36
2013 Busch A, Hertel KJ. HEXEvent: a database of Human EXon splicing Events. Nucleic Acids Research. 41: D118-24. PMID 23118488 DOI: 10.1093/Nar/Gks969  0.36
2012 Busch A, Hertel KJ. Extensive regulation of NAGNAG alternative splicing: new tricks for the spliceosome? Genome Biology. 13: 143. PMID 22356731 DOI: 10.1186/Gb3999  0.36
2012 Busch A, Hertel KJ. Evolution of SR protein and hnRNP splicing regulatory factors. Wiley Interdisciplinary Reviews. Rna. 3: 1-12. PMID 21898828 DOI: 10.1002/Wrna.100  0.36
2011 Shepard PJ, Choi EA, Lu J, Flanagan LA, Hertel KJ, Shi Y. Complex and dynamic landscape of RNA polyadenylation revealed by PAS-Seq. Rna (New York, N.Y.). 17: 761-72. PMID 21343387 DOI: 10.1261/Rna.2581711  0.36
2010 Crabb TL, Lam BJ, Hertel KJ. Retention of spliceosomal components along ligated exons ensures efficient removal of multiple introns. Rna (New York, N.Y.). 16: 1786-96. PMID 20610656 DOI: 10.1261/Rna.2186510  1
2010 Hicks MJ, Mueller WF, Shepard PJ, Hertel KJ. Competing upstream 5' splice sites enhance the rate of proximal splicing. Molecular and Cellular Biology. 30: 1878-86. PMID 20123971 DOI: 10.1128/Mcb.01071-09  0.36
2009 Geib T, Hertel KJ. Restoration of full-length SMN promoted by adenoviral vectors expressing RNA antisense oligonucleotides embedded in U7 snRNAs. Plos One. 4: e8204. PMID 19997596 DOI: 10.1371/Journal.Pone.0008204  0.76
2009 Tannukit S, Crabb TL, Hertel KJ, Wen X, Jans DA, Paine ML. Identification of a novel nuclear localization signal and speckle-targeting sequence of tuftelin-interacting protein 11, a splicing factor involved in spliceosome disassembly. Biochemical and Biophysical Research Communications. 390: 1044-50. PMID 19857462 DOI: 10.1016/J.Bbrc.2009.10.111  1
2009 Fox-Walsh KL, Hertel KJ. Splice-site pairing is an intrinsically high fidelity process. Proceedings of the National Academy of Sciences of the United States of America. 106: 1766-71. PMID 19179398 DOI: 10.1073/Pnas.0813128106  0.36
2009 Kotlajich MV, Crabb TL, Hertel KJ. Spliceosome assembly pathways for different types of alternative splicing converge during commitment to splice site pairing in the A complex. Molecular and Cellular Biology. 29: 1072-82. PMID 19064642 DOI: 10.1128/Mcb.01071-08  1
2008 Kotlajich MV, Hertel KJ. Death by splicing: tumor suppressor RBM5 freezes splice-site pairing. Molecular Cell. 32: 162-4. PMID 18951082 DOI: 10.1016/J.Molcel.2008.10.008  0.92
2006 Sciabica KS, Hertel KJ. The splicing regulators Tra and Tra2 are unusually potent activators of pre-mRNA splicing. Nucleic Acids Research. 34: 6612-20. PMID 17135210 DOI: 10.1093/Nar/Gkl984  0.36
2006 Dou Y, Fox-Walsh KL, Baldi PF, Hertel KJ. Genomic splice-site analysis reveals frequent alternative splicing close to the dominant splice site. Rna (New York, N.Y.). 12: 2047-56. PMID 17053087 DOI: 10.1261/Rna.151106  0.36
2006 Hicks MJ, Yang CR, Kotlajich MV, Hertel KJ. Linking splicing to Pol II transcription stabilizes pre-mRNAs and influences splicing patterns. Plos Biology. 4: e147. PMID 16640457 DOI: 10.1371/Journal.Pbio.0040147  0.92
2005 Hicks MJ, Lam BJ, Hertel KJ. Analyzing mechanisms of alternative pre-mRNA splicing using in vitro splicing assays. Methods (San Diego, Calif.). 37: 306-13. PMID 16314259 DOI: 10.1016/J.Ymeth.2005.07.012  1
2005 Fox-Walsh KL, Dou Y, Lam BJ, Hung SP, Baldi PF, Hertel KJ. The architecture of pre-mRNAs affects mechanisms of splice-site pairing. Proceedings of the National Academy of Sciences of the United States of America. 102: 16176-81. PMID 16260721 DOI: 10.1073/Pnas.0508489102  0.36
2005 Madocsai C, Lim SR, Geib T, Lam BJ, Hertel KJ. Correction of SMN2 Pre-mRNA splicing by antisense U7 small nuclear RNAs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 1013-22. PMID 16226920 DOI: 10.1016/J.Ymthe.2005.08.022  1
2005 Freund M, Hicks MJ, Konermann C, Otte M, Hertel KJ, Schaal H. Extended base pair complementarity between U1 snRNA and the 5' splice site does not inhibit splicing in higher eukaryotes, but rather increases 5' splice site recognition. Nucleic Acids Research. 33: 5112-9. PMID 16155183 DOI: 10.1093/Nar/Gki824  0.36
2005 Ibrahim EC, Schaal TD, Hertel KJ, Reed R, Maniatis T. Serine/arginine-rich protein-dependent suppression of exon skipping by exonic splicing enhancers. Proceedings of the National Academy of Sciences of the United States of America. 102: 5002-7. PMID 15753297 DOI: 10.1073/Pnas.0500543102  0.36
2005 Hertel KJ, Graveley BR. RS domains contact the pre-mRNA throughout spliceosome assembly. Trends in Biochemical Sciences. 30: 115-8. PMID 15752982 DOI: 10.1016/J.Tibs.2005.01.002  0.36
2004 Lim SR, Hertel KJ. Commitment to splice site pairing coincides with A complex formation. Molecular Cell. 15: 477-83. PMID 15304226 DOI: 10.1016/J.Molcel.2004.06.025  0.96
2003 Lam BJ, Bakshi A, Ekinci FY, Webb J, Graveley BR, Hertel KJ. Enhancer-dependent 5'-splice site control of fruitless pre-mRNA splicing. The Journal of Biological Chemistry. 278: 22740-7. PMID 12646561 DOI: 10.1074/Jbc.M301036200  0.36
2002 Lam BJ, Hertel KJ. A general role for splicing enhancers in exon definition. Rna (New York, N.Y.). 8: 1233-41. PMID 12403462 DOI: 10.1017/S1355838202028030  1
2001 Lim SR, Hertel KJ. Modulation of survival motor neuron pre-mRNA splicing by inhibition of alternative 3' splice site pairing. The Journal of Biological Chemistry. 276: 45476-83. PMID 11584013 DOI: 10.1074/Jbc.M107632200  0.96
2001 Graveley BR, Hertel KJ, Maniatis T. The role of U2AF35 and U2AF65 in enhancer-dependent splicing. Rna (New York, N.Y.). 7: 806-18. PMID 11421359 DOI: 10.1017/S1355838201010317  0.36
1999 Hertel KJ, Maniatis T. Serine-arginine (SR)-rich splicing factors have an exon-independent function in pre-mRNA splicing. Proceedings of the National Academy of Sciences of the United States of America. 96: 2651-5. PMID 10077565 DOI: 10.1073/Pnas.96.6.2651  0.36
1999 Graveley BR, Hertel KJ, Maniatis T. SR proteins are 'locators' of the RNA splicing machinery. Current Biology : Cb. 9: R6-7. PMID 9889128 DOI: 10.1016/S0960-9822(99)80032-3  0.36
1998 Hertel KJ, Stage-Zimmermann TK, Ammons G, Uhlenbeck OC. Thermodynamic dissection of the substrate-ribozyme interaction in the hammerhead ribozyme. Biochemistry. 37: 16983-8. PMID 9836592 DOI: 10.1021/Bi981740B  0.36
1998 Graveley BR, Hertel KJ, Maniatis T. A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers. The Embo Journal. 17: 6747-56. PMID 9822617 DOI: 10.1093/Emboj/17.22.6747  0.36
1998 Hertel KJ, Maniatis T. The function of multisite splicing enhancers. Molecular Cell. 1: 449-55. PMID 9660929 DOI: 10.1016/S1097-2765(00)80045-3  0.36
1997 Hertel KJ, Peracchi A, Uhlenbeck OC, Herschlag D. Use of intrinsic binding energy for catalysis by an RNA enzyme. Proceedings of the National Academy of Sciences of the United States of America. 94: 8497-502. PMID 9238005 DOI: 10.1073/Pnas.94.16.8497  0.36
1997 Hertel KJ, Lynch KW, Maniatis T. Common themes in the function of transcription and splicing enhancers. Current Opinion in Cell Biology. 9: 350-7. PMID 9159075 DOI: 10.1016/S0955-0674(97)80007-5  0.36
1996 Hertel KJ, Herschlag D, Uhlenbeck OC. Specificity of hammerhead ribozyme cleavage. The Embo Journal. 15: 3751-7. PMID 8670879  0.36
1995 Hertel KJ, Uhlenbeck OC. The internal equilibrium of the hammerhead ribozyme reaction. Biochemistry. 34: 1744-9. PMID 7849034 DOI: 10.1021/Bi00005A031  0.36
1995 Stage TK, Hertel KJ, Uhlenbeck OC. Inhibition of the hammerhead ribozyme by neomycin. Rna (New York, N.Y.). 1: 95-101. PMID 7489494 DOI: 10.22458/Rna.V1I1.287  0.36
1994 Hertel KJ, Herschlag D, Uhlenbeck OC. A kinetic and thermodynamic framework for the hammerhead ribozyme reaction Biochemistry. 33: 3374-3385. PMID 8136375 DOI: 10.1021/Bi00177A031  0.36
1992 Hertel KJ, Pardi A, Uhlenbeck OC, Koizumi M, Ohtsuka E, Uesugi S, Cedergren R, Eckstein F, Gerlach WL, Hodgson R. Numbering system for the hammerhead. Nucleic Acids Research. 20: 3252. PMID 1620624 DOI: 10.1093/Nar/20.12.3252  0.36
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