Charis Eng - Publications

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
Area:
Genetics, Molecular Biology

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Steele M, Uljarević M, Rached G, Frazier TW, Phillips JM, Libove RA, Busch RM, Klaas P, Martinez-Agosto JA, Srivastava S, Eng C, Sahin M, Hardan AY. Psychiatric Characteristics Across Individuals With Mutations. Frontiers in Psychiatry. 12: 672070. PMID 34489750 DOI: 10.3389/fpsyt.2021.672070  1
2021 Kim SJ, Lubiński J, Huzarski T, Møller P, Armel S, Karlan BY, Senter L, Eisen A, Foulkes WD, Singer CF, Tung N, Bordeleau L, Neuhausen SL, Olopade OI, Eng C, et al. Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 34426412 DOI: 10.1158/1055-9965.EPI-21-0296  1
2021 Uljarević M, Frazier TW, Rached G, Busch RM, Klaas P, Srivastava S, Martinez-Agosto JA, Sahin M, Eng C, Hardan AY. Toward better characterization of restricted and repetitive behaviors in individuals with germline heterozygous PTEN mutations. American Journal of Medical Genetics. Part A. PMID 34423884 DOI: 10.1002/ajmg.a.62458  1
2021 Hou Y, Zhou Y, Gack MU, Lathia JD, Kallianpur A, Mehra R, Chan TA, Jung JU, Jehi L, Eng C, Cheng F. Multimodal single-cell omics analysis identifies epithelium-immune cell interactions and immune vulnerability associated with sex differences in COVID-19. Signal Transduction and Targeted Therapy. 6: 292. PMID 34330889 DOI: 10.1038/s41392-021-00709-x  1
2021 Jia M, Sangwan N, Tzeng A, Eng C. Interplay Between Class II HLA Genotypes and the Microbiome and Immune Phenotypes in Individuals With PTEN Hamartoma Tumor Syndrome. Jco Precision Oncology. 5. PMID 34250407 DOI: 10.1200/PO.20.00374  1
2021 Khare A, Burke CA, Heald B, O'Malley M, LaGuardia L, Milicia S, Cruise M, Eng C, Mankaney G. Endoscopic Findings in Patients With PTEN Hamartoma Tumor Syndrome Undergoing Surveillance. Journal of Clinical Gastroenterology. PMID 34231499 DOI: 10.1097/MCG.0000000000001580  1
2021 Grencewicz DJ, Romigh T, Thacker S, Abbas A, Jaini R, Luse D, Eng C. Redefining the PTEN promoter: Identification of novel upstream transcription start regions. Human Molecular Genetics. PMID 34218272 DOI: 10.1093/hmg/ddab175  1
2021 Jang H, Smith IN, Eng C, Nussinov R. The mechanism of full activation of tumor suppressor PTEN at the phosphoinositide-enriched membrane. Iscience. 24: 102438. PMID 34113810 DOI: 10.1016/j.isci.2021.102438  1
2021 Doherty C, Kinzy TG, Ferguson L, Altemus J, Hermann BP, Eng C, Najm I, Busch RM. The role of genetic polymorphisms in executive functioning performance in temporal lobe epilepsy. Epilepsy & Behavior : E&B. 121: 108088. PMID 34102472 DOI: 10.1016/j.yebeh.2021.108088  1
2021 Jaini R, Wolf MR, Yu Q, King AT, Frazier TW, Eng C. Maternal genetics influences fetal neurodevelopment and postnatal autism spectrum disorder-like phenotype by modulating in-utero immunosuppression. Translational Psychiatry. 11: 348. PMID 34091589 DOI: 10.1038/s41398-021-01472-x  1
2021 Sarn N, Thacker S, Lee H, Eng C. Germline nuclear-predominant Pten murine model exhibits impaired social and perseverative behavior, microglial activation, and increased oxytocinergic activity. Molecular Autism. 12: 41. PMID 34088332 DOI: 10.1186/s13229-021-00448-4  1
2021 Thacker S, Eng C. Transcriptome-(phospho)proteome characterization of brain of a germline model of cytoplasmic-predominant Pten expression with autism-like phenotypes. Npj Genomic Medicine. 6: 42. PMID 34078911 DOI: 10.1038/s41525-021-00201-z  1
2021 Lundy SD, Vij SC, Eng C. Reply to Eugenio Ventimiglia, Edoardo Pozzi, Massimo Alfano, Francesco Montorsi, and Andrea Salonia's Letter to the Editor re: Scott D. Lundy, Naseer Sangwan, Neel V. Parekh, et al. Functional and Taxonomic Dysbiosis of the Gut, Urine, and Semen Microbiomes in Male Infertility. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2021.01.014. European Urology. PMID 33994216 DOI: 10.1016/j.eururo.2021.04.044  1
2021 Tzeng A, Sangwan N, Jia M, Liu CC, Keslar KS, Downs-Kelly E, Fairchild RL, Al-Hilli Z, Grobmyer SR, Eng C. Human breast microbiome correlates with prognostic features and immunological signatures in breast cancer. Genome Medicine. 13: 60. PMID 33863341 DOI: 10.1186/s13073-021-00874-2  1
2021 Taylor H, Yerlioglu D, Phen C, Ballauff A, Nedelkopoulou N, Spier I, Loverdos I, Busoni VB, Heise J, Dale P, Meij T, Sweet K, Cohen MC, Fox VL, Mas E, ... ... Eng C, et al. mTOR inhibitors reduce enteropathy, intestinal bleeding and colectomy rate in juvenile polyposis of infancy due to PTEN-BMPR1A deletion syndrome. Human Molecular Genetics. PMID 33822054 DOI: 10.1093/hmg/ddab094  1
2021 Yehia L, Liu D, Fu S, Iyer P, Eng C. Non-canonical role of wild-type SEC23B in the cellular stress response pathway. Cell Death & Disease. 12: 304. PMID 33753724 DOI: 10.1038/s41419-021-03589-9  1
2021 Hardan AY, Jo B, Frazier TW, Klaas P, Busch RM, Dies KA, Filip-Dhima R, Snow AV, Eng C, Hanna R, Zhang B, Sahin M. A randomized double-blind controlled trial of everolimus in individuals with mutations: Study design and statistical considerations. Contemporary Clinical Trials Communications. 21: 100733. PMID 33644493 DOI: 10.1016/j.conctc.2021.100733  1
2021 Uljarević M, Frazier TW, Rached G, Busch RM, Klaas P, Srivastava S, Martinez-Agosto JA, Sahin M, Eng C, Hardan AY. Brief Report: Role of Parent-Reported Executive Functioning and Anxiety in Insistence on Sameness in Individuals with Germline PTEN Mutations. Journal of Autism and Developmental Disorders. PMID 33595755 DOI: 10.1007/s10803-021-04881-5  0.01
2021 Lundy SD, Sangwan N, Parekh NV, Selvam MKP, Gupta S, McCaffrey P, Bessoff K, Vala A, Agarwal A, Sabanegh ES, Vij SC, Eng C. Functional and Taxonomic Dysbiosis of the Gut, Urine, and Semen Microbiomes in Male Infertility. European Urology. PMID 33573862 DOI: 10.1016/j.eururo.2021.01.014  1
2021 Cheng F, Zhao J, Wang Y, Lu W, Liu Z, Zhou Y, Martin WR, Wang R, Huang J, Hao T, Yue H, Ma J, Hou Y, Castrillon JA, Fang J, ... ... Eng C, et al. Comprehensive characterization of protein-protein interactions perturbed by disease mutations. Nature Genetics. PMID 33558758 DOI: 10.1038/s41588-020-00774-y  1
2021 Zhou Y, Zhao J, Fang J, Martin W, Li L, Nussinov R, Chan TA, Eng C, Cheng F. My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype. Genome Biology. 22: 53. PMID 33514395 DOI: 10.1186/s13059-021-02269-3  1
2021 Frazier TW, Jaini R, Busch RM, Wolf M, Sadler T, Klaas P, Hardan AY, Martinez-Agosto JA, Sahin M, Eng C. Cross-level analysis of molecular and neurobehavioral function in a prospective series of patients with germline heterozygous PTEN mutations with and without autism. Molecular Autism. 12: 5. PMID 33509259 DOI: 10.1186/s13229-020-00406-6  1
2021 Eng C. On the shoulders of giants. Human Molecular Genetics. PMID 33423061 DOI: 10.1093/hmg/ddaa265  0.01
2020 Kim RH, Wang X, Evans AJ, Campbell SC, Nguyen JK, Farncombe KM, Eng C. Early-onset renal cell carcinoma in PTEN harmatoma tumour syndrome. Npj Genomic Medicine. 5: 40. PMID 34584106 DOI: 10.1038/s41525-020-00148-7  1
2020 Zeng X, Zhu S, Lu W, Liu Z, Huang J, Zhou Y, Fang J, Huang Y, Guo H, Li L, Trapp BD, Nussinov R, Eng C, Loscalzo J, Cheng F. Target identification among known drugs by deep learning from heterogeneous networks. Chemical Science. 11: 1775-1797. PMID 34123272 DOI: 10.1039/c9sc04336e  1
2020 Sankunny M, Eng C. Identification of nuclear export signal in KLLN suggests potential role in proteasomal degradation in cancer cells. Oncotarget. 11: 4625-4636. PMID 33400740 DOI: 10.18632/oncotarget.27833  1
2020 Akhavanfard S, Yehia L, Padmanabhan R, Reynolds JP, Ni Y, Eng C. Germline EGFR variants are over-represented in adolescents and young adults (AYA) with adrenocortical carcinoma. Human Molecular Genetics. PMID 33326033 DOI: 10.1093/hmg/ddaa268  1
2020 Eng C. Passing of the baton. Endocrine-Related Cancer. 27: E7-E8. PMID 33269704 DOI: 10.1530/ERC-20-0426  0.01
2020 Bancos I, Atkinson E, Eng C, Young WF, Neumann HPH. Maternal and fetal outcomes in phaeochromocytoma and pregnancy: a multicentre retrospective cohort study and systematic review of literature. The Lancet. Diabetes & Endocrinology. PMID 33248478 DOI: 10.1016/S2213-8587(20)30363-6  1
2020 Ramkumar RR, Murthy PB, Nguyen JK, McKenney J, Eng C, Campbell SC. PTEN Hamartoma Tumor Syndrome: A Case of Renal Cell Carcinoma in a Young Female. Urology. PMID 33227300 DOI: 10.1016/j.urology.2020.11.024  1
2020 Heald B, Keel E, Marquard J, Burke CA, Kalady MF, Church JM, Liska D, Mankaney G, Hurley K, Eng C. Using chatbots to screen for heritable cancer syndromes in patients undergoing routine colonoscopy. Journal of Medical Genetics. PMID 33168571 DOI: 10.1136/jmedgenet-2020-107294  1
2020 Thacker S, Sefyi M, Eng C. Alternative splicing landscape of the neural transcriptome in a cytoplasmic-predominant Pten expression murine model of autism-like Behavior. Translational Psychiatry. 10: 380. PMID 33159038 DOI: 10.1038/s41398-020-01068-x  1
2020 Zhou Y, Hou Y, Shen J, Mehra R, Kallianpur A, Culver DA, Gack MU, Farha S, Zein J, Comhair S, Fiocchi C, Stappenbeck T, Chan T, Eng C, Jung JU, et al. A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19. Plos Biology. 18: e3000970. PMID 33156843 DOI: 10.1371/journal.pbio.3000970  1
2020 Kim RH, Wang X, Evans AJ, Campbell SC, Nguyen JK, Farncombe KM, Eng C. Early-onset renal cell carcinoma in harmatoma tumour syndrome. Npj Genomic Medicine. 5: 40. PMID 33083010 DOI: 10.1038/s41525-020-00148-7  1
2020 Eng C, Plass C. Cancer (Epi)Genomics Comes of Age. Human Molecular Genetics. 29: R127. PMID 33079189 DOI: 10.1093/hmg/ddaa207  1
2020 Kotsopoulos J, Gronwald J, McCuaig JM, Karlan BY, Eisen A, Tung N, Bordeleau L, Senter L, Eng C, Couch F, Fruscio R, Weitzel JN, Olopade O, Singer CF, Pal T, et al. Breastfeeding and the risk of epithelial ovarian cancer among women with a BRCA1 or BRCA2 mutation. Gynecologic Oncology. PMID 33010967 DOI: 10.1016/j.ygyno.2020.09.037  1
2020 Busch RM, Yehia L, Bazeley P, Seyfi M, Blümcke I, Hermann BP, Najm IM, Eng C. Verbal memory dysfunction is associated with alterations in brain transcriptome in dominant temporal lobe epilepsy. Epilepsia. PMID 32945555 DOI: 10.1111/Epi.16673  1
2020 Karimi D, Peters JM, Ouaalam A, Prabhu SP, Sahin M, Krueger DA, Kolevzon A, Eng C, Warfield SK, Gholipour A. LEARNING TO DETECT BRAIN LESIONS FROM NOISY ANNOTATIONS. Proceedings. Ieee International Symposium On Biomedical Imaging. 2020: 1910-1914. PMID 32879655 DOI: 10.1109/isbi45749.2020.9098599  1
2020 Abbas A, Padmanabhan R, Eng C. Metabolic stress regulates genome-wide transcription in a PTEN-dependent manner. Human Molecular Genetics. PMID 32744308 DOI: 10.1093/Hmg/Ddaa168  1
2020 Novelli G, Novelli A, Borgiani P, Cocciadiferro D, Biancolella M, Agolini E, Pietrosanto M, Casalone R, Helmer-Citterich M, Giardina E, Jain SK, Wei W, Eng C, Pandolfi PP. WWP1 germline variants are associated with normocephalic autism spectrum disorder. Cell Death & Disease. 11: 529. PMID 32699206 DOI: 10.1038/S41419-020-2681-Z  1
2020 Zhou Y, Hou Y, Shen J, Kallianpur A, Zein J, Culver DA, Farha S, Comhair S, Fiocchi C, Gack MU, Mehra R, Stappenbeck T, Chan T, Eng C, Jung JU, et al. A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19. Chemrxiv : the Preprint Server For Chemistry. PMID 32676577 DOI: 10.26434/chemrxiv.12579137  1
2020 Hou Y, Zhao J, Martin W, Kallianpur A, Chung MK, Jehi L, Sharifi N, Erzurum S, Eng C, Cheng F. New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis. Bmc Medicine. 18: 216. PMID 32664879 DOI: 10.1186/S12916-020-01673-Z  1
2020 Shay E, Sangwan N, Padmanabhan R, Lundy S, Burkey B, Eng C. Bacteriome and mycobiome and bacteriome-mycobiome interactions in head and neck squamous cell carcinoma. Oncotarget. 11: 2375-2386. PMID 32637029 DOI: 10.18632/Oncotarget.27629  1
2020 Castrillon JA, Eng C, Cheng F. Pharmacogenomics for Immunotherapy and Immune-related Cardiotoxicity. Human Molecular Genetics. PMID 32620943 DOI: 10.1093/Hmg/Ddaa137  1
2020 Jaini R, Loya MG, King AT, Thacker S, Sarn NB, Yu Q, Stark GR, Eng C. Germline PTEN mutations are associated with a skewed peripheral immune repertoire in humans and mice. Human Molecular Genetics. PMID 32588888 DOI: 10.1093/Hmg/Ddaa118  1
2020 Yehia L, Eng C. PTEN hamartoma tumour syndrome: What happens when there is no PTEN germline mutation? Human Molecular Genetics. PMID 32568377 DOI: 10.1093/Hmg/Ddaa127  1
2020 Kang SC, Jaini R, Hitomi M, Lee H, Sarn N, Thacker S, Eng C. Decreased nuclear Pten in neural stem cells contributes to deficits in neuronal maturation. Molecular Autism. 11: 43. PMID 32487265 DOI: 10.1186/S13229-020-00337-2  1
2020 Lee YR, Yehia L, Kishikawa T, Ni Y, Leach B, Zhang J, Panch N, Liu J, Wei W, Eng C, Pandolfi PP. WWP1 Gain-of-Function Inactivation of PTEN in Cancer Predisposition. The New England Journal of Medicine. 382: 2103-2116. PMID 32459922 DOI: 10.1056/Nejmoa1914919  1
2020 Mighell TL, Thacker S, Fombonne E, Eng C, O'Roak BJ. An Integrated Deep-Mutational-Scanning Approach Provides Clinical Insights on PTEN Genotype-Phenotype Relationships. American Journal of Human Genetics. PMID 32442409 DOI: 10.1016/J.Ajhg.2020.04.014  1
2020 Larsen LV, Mirebeau-Prunier D, Imai T, Alvarez-Escola C, Hasse-Lazar K, Censi S, Castroneves LA, Sakurai A, Kihara M, Horiuchi K, Barbu VD, Borson-Chazot F, Gimenez-Roqueplo AP, Pigny P, Pinson S, ... ... Eng C, et al. Primary hyperparathyroidism as first manifestation in MEN 2A: an international multicenter study. Endocrine Connections. PMID 32375120 DOI: 10.1530/Ec-20-0163  1
2020 Akhavanfard S, Padmanabhan R, Yehia L, Cheng F, Eng C. Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors. Nature Communications. 11: 2206. PMID 32371905 DOI: 10.1038/S41467-020-16067-1  1
2020 Ngeow J, Eng C. Oh GxE! The Complexity of Body Mass Index and Colon Cancer Risk. Journal of the National Cancer Institute. PMID 32324885 DOI: 10.1093/Jnci/Djaa059  1
2020 Sheehan M, Heald B, Yanda C, Kelly ED, Grobmyer S, Eng C, Kalady M, Pederson H. Investigating the Link between Lynch Syndrome and Breast Cancer. European Journal of Breast Health. 16: 106-109. PMID 32285031 DOI: 10.5152/Ejbh.2020.5198  1
2020 Liu C, Zhao J, Lu W, Dai Y, Hockings J, Zhou Y, Nussinov R, Eng C, Cheng F. Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes. Plos Computational Biology. 16: e1007701. PMID 32101536 DOI: 10.1371/Journal.Pcbi.1007701  1
2020 Sarn N, Jaini R, Thacker S, Lee H, Dutta R, Eng C. Cytoplasmic-predominant Pten increases microglial activation and synaptic pruning in a murine model with autism-like phenotype. Molecular Psychiatry. PMID 32055008 DOI: 10.1038/S41380-020-0681-0  1
2020 Yehia L, Eng C. The APCs of PTCs: Adenomatous Polyposis Syndrome and the Thyroid. Thyroid : Official Journal of the American Thyroid Association. PMID 32041494 DOI: 10.1089/Thy.2020.0109  1
2020 Hockings JK, Pasternak AL, Erwin AL, Mason NT, Eng C, Hicks JK. Pharmacogenomics: An evolving clinical tool for precision medicine. Cleveland Clinic Journal of Medicine. 87: 91-99. PMID 32015062 DOI: 10.3949/Ccjm.87A.19073  1
2020 Yehia L, Seyfi M, Niestroj LM, Padmanabhan R, Ni Y, Frazier TW, Lal D, Eng C. Copy Number Variation and Clinical Outcomes in Patients With Germline PTEN Mutations. Jama Network Open. 3: e1920415. PMID 32003824 DOI: 10.1001/jamanetworkopen.2019.20415  1
2020 Zeng X, Zhu S, Lu W, Liu Z, Huang J, Zhou Y, Fang J, Huang Y, Guo H, Li L, Trapp BD, Nussinov R, Eng C, Loscalzo J, Cheng F. Target identification among known drugs by deep learning from heterogeneous networks Chemical Science. 11: 1775-1797. DOI: 10.1039/C9Sc04336E  0.01
2020 Habash N, Rybicki L, Selvakumar PKC, Radhakrishnan K, Eng C. Tu2015 GASTROINTESTINAL AND HEPATIC MANIFESTATIONS OF PTEN HAMARTOMA TUMOR SYNDROME IN CHILDREN: A RETROSPECTIVE REVIEW FROM A LARGE MEDICAL CENTER WITH A PTEN MULTIDISCIPLINARY TEAM Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)33800-2  1
2020 Khare A, Burke CA, Heald B, O'Malley M, LaGuardia LA, Cruise MW, Liska D, Kalady M, Church JM, Eng C, Mankaney GN. Tu1217 THE EFFICACY OF LOWER ENDOSCOPIC SURVEILLANCE IN COWDEN'S SYNDROME Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)33228-5  1
2020 Akhavanfard S, Yehia L, Padmanabhan R, Romigh T, Ni Y, Eng C. 1. Germline EGFR variants over-represented in adolescent and young adult (AYA) females with adrenocortical carcinoma Cancer Genetics and Cytogenetics. 244: 1. DOI: 10.1016/J.Cancergen.2020.04.005  1
2019 Neumann HPH, Young WF, Eng C. Pheochromocytoma and Paraganglioma. Reply. The New England Journal of Medicine. 381: 1883. PMID 31693823 DOI: 10.1056/Nejmc1912022  1
2019 Kotsopoulos J, Gronwald J, Lubinski J, McCuaig J, Lynch HT, Neuhausen SL, Foulkes WD, Weitzel JN, Senter L, Tung N, Eng C, Karlan B, Sun P, Narod SA. Does preventive oophorectomy increase the risk of depression in BRCA mutation carriers? Menopause (New York, N.Y.). PMID 31644510 DOI: 10.1097/Gme.0000000000001437  1
2019 Busch RM, Srivastava S, Hogue O, Frazier TW, Klaas P, Hardan A, Martinez-Agosto JA, Sahin M, Eng C. Neurobehavioral phenotype of autism spectrum disorder associated with germline heterozygous mutations in PTEN. Translational Psychiatry. 9: 253. PMID 31594918 DOI: 10.1038/S41398-019-0588-1  1
2019 Neumann HPH, Schmid KW, Eng C. Morphology and etiology of pheochromocytoma. Pathologe. 40: 316-317. PMID 31588958 DOI: 10.1007/S00292-019-00663-0  1
2019 Ngeow J, Eng C. PTEN in Hereditary and Sporadic Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 31570378 DOI: 10.1101/Cshperspect.A036087  1
2019 Yehia L, Ni Y, Feng F, Seyfi M, Sadler T, Frazier TW, Eng C. Distinct Alterations in Tricarboxylic Acid Cycle Metabolites Associate with Cancer and Autism Phenotypes in Cowden Syndrome and Bannayan-Riley-Ruvalcaba Syndrome. American Journal of Human Genetics. PMID 31564436 DOI: 10.1016/J.Ajhg.2019.09.004  1
2019 Abbas A, Romigh T, Eng C. PTEN interacts with RNA polymerase II to dephosphorylate polymerase II C-terminal domain. Oncotarget. 10: 4951-4959. PMID 31452836 DOI: 10.18632/Oncotarget.27128  1
2019 Yehia L, Keel E, Eng C. The Clinical Spectrum of Mutations. Annual Review of Medicine. PMID 31433956 DOI: 10.1146/Annurev-Med-052218-125823  1
2019 Neumann HPH, Tsoy U, Bancos I, Amodru V, Walz MK, Tirosh A, Kaur RJ, McKenzie T, Qi X, Bandgar T, Petrov R, Yukina MY, Roslyakova A, van der Horst-Schrivers ANA, Berends AMA, ... ... Eng C, et al. Comparison of Pheochromocytoma-Specific Morbidity and Mortality Among Adults With Bilateral Pheochromocytomas Undergoing Total Adrenalectomy vs Cortical-Sparing Adrenalectomy. Jama Network Open. 2: e198898. PMID 31397861 DOI: 10.1001/jamanetworkopen.2019.8898  1
2019 Neumann HPH, Young WF, Eng C. Pheochromocytoma and Paraganglioma. The New England Journal of Medicine. 381: 552-565. PMID 31390501 DOI: 10.1056/Nejmra1806651  1
2019 Cheng F, Lu W, Liu C, Fang J, Hou Y, Handy DE, Wang R, Zhao Y, Yang Y, Huang J, Hill DE, Vidal M, Eng C, Loscalzo J. A genome-wide positioning systems network algorithm for in silico drug repurposing. Nature Communications. 10: 3476. PMID 31375661 DOI: 10.1038/S41467-019-10744-6  1
2019 Chong ST, Tan KM, Kok CYL, Guan SP, Lai SH, Lim C, Hu J, Sturgis C, Eng C, Lam PYP, Ngeow J. IL13RA2 is differentially regulated in Papillary Thyroid Carcinoma versus Follicular Thyroid Carcinoma. The Journal of Clinical Endocrinology and Metabolism. PMID 31290966 DOI: 10.1210/Jc.2019-00040  1
2019 Huang Y, Fang J, Lu W, Wang Z, Wang Q, Hou Y, Jiang X, Reizes O, Lathia J, Nussinov R, Eng C, Cheng F. A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling. Cell Chemical Biology. PMID 31178408 DOI: 10.1016/J.Chembiol.2019.05.004  1
2019 Abbas A, Padmanabhan R, Romigh T, Eng C. PTEN modulates gene transcription by redistributing genome-wide RNA polymerase II occupancy. Human Molecular Genetics. PMID 31127935 DOI: 10.1093/Hmg/Ddz112  1
2019 Smith IN, Thacker S, Seyfi M, Cheng F, Eng C. Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer. American Journal of Human Genetics. PMID 31006514 DOI: 10.1016/J.Ajhg.2019.03.009  1
2019 Getz TM, Hoffman GS, Padmanabhan R, Villa-Forte A, Roselli EE, Blackstone E, Johnston D, Pettersson G, Soltesz E, Svensson LG, Calabrese LH, Clifford AH, Eng C. Microbiomes of Inflammatory Thoracic Aortic Aneurysms Due to Giant Cell Arteritis and Clinically Isolated Aortitis Differ From Those of Non-Inflammatory Aneurysms. Pathogens & Immunity. 4: 105-123. PMID 30993253 DOI: 10.20411/pai.v4i1.269  1
2019 Hoffman GS, Getz TM, Padmanabhan R, Villa-Forte A, Clifford AH, Funchain P, Sankunny M, Perry JD, Blandford A, Kosmorsky G, Lystad L, Calabrese LH, Eng C. The Microbiome of Temporal Arteries. Pathogens & Immunity. 4: 21-38. PMID 30993251 DOI: 10.20411/pai.v4i1.270  1
2019 Metcalfe K, Eisen A, Senter L, Armel S, Bordeleau L, Meschino WS, Pal T, Lynch HT, Tung NM, Kwong A, Ainsworth P, Karlan B, Moller P, Eng C, Weitzel JN, et al. International trends in the uptake of cancer risk reduction strategies in women with a BRCA1 or BRCA2 mutation. British Journal of Cancer. PMID 30971774 DOI: 10.1038/S41416-019-0446-1  1
2019 Yehia L, Eng C. Largescale population genomics versus deep phenotyping: Brute force or elegant pragmatism towards precision medicine. Npj Genomic Medicine. 4: 6. PMID 30937181 DOI: 10.1038/S41525-019-0080-0  1
2019 Cheng F, Eng C. PTEN Mutations Trigger Resistance to Immunotherapy. Trends in Molecular Medicine. PMID 30928438 DOI: 10.1016/J.Molmed.2019.03.003  1
2019 Doherty C, Hogue O, Floden DP, Altemus JB, Najm IM, Eng C, Busch RM. BDNF and COMT, but not APOE, alleles are associated with psychiatric symptoms in refractory epilepsy. Epilepsy & Behavior : E&B. 94: 131-136. PMID 30909076 DOI: 10.1016/J.Yebeh.2019.02.032  1
2019 Wanchai V, Jin J, Bircan E, Eng C, Orloff M. Genome-wide tracts of homozygosity and exome analyses reveal repetitive elements with Barrets esophagus/esophageal adenocarcinoma risk. Bmc Bioinformatics. 20: 98. PMID 30871476 DOI: 10.1186/S12859-019-2622-Y  1
2019 Feng F, Yehia L, Eng C. Pro-tumorigenic non-pump function of sodium iodide symporter: A reimagined Trojan horse? Oncotarget. 10: 688-689. PMID 30774768 DOI: 10.18632/Oncotarget.26596  1
2019 Lee H, Thacker S, Sarn N, Dutta R, Eng C. Constitutional mislocalization of Pten drives precocious maturation in oligodendrocytes and aberrant myelination in model of autism spectrum disorder. Translational Psychiatry. 9: 13. PMID 30664625 DOI: 10.1038/S41398-018-0364-7  1
2019 Castinetti F, Waguespack SG, Machens A, Uchino S, Lazaar K, Sanso G, Else T, Dvorakova S, Qi XP, Elisei R, Maia AL, Glod J, Lourenço DM, Valdes N, Mathiesen J, ... ... Eng C, et al. Natural history, treatment, and long-term follow up of patients with multiple endocrine neoplasia type 2B: an international, multicentre, retrospective study. The Lancet. Diabetes & Endocrinology. PMID 30660595 DOI: 10.1016/S2213-8587(18)30336-X  1
2019 Yehia L, Ngeow J, Eng C. PTEN-opathies: from biological insights to evidence-based precision medicine. The Journal of Clinical Investigation. PMID 30614812 DOI: 10.1172/Jci121277  1
2019 Cheng F, Liang H, Butte AJ, Eng C, Nussinov R. Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health. Pharmacological Reviews. 71: 1-19. PMID 30545954 DOI: 10.1124/Pr.118.016253  1
2019 Khare A, Burke CA, Leach B, O'Malley M, LaGuardia L, Eng C, Mankaney G. 2894 The Gastrointestinal Phenotype of Cowden’s Syndrome and Effects of Surveillance The American Journal of Gastroenterology. 114. DOI: 10.14309/01.Ajg.0000601108.52032.50  1
2019 Bancos I, Khudiakova N, Bandgar T, Bausch B, Ariza NI, Kaur RJ, Pereira M, Young W, Eng C, Neumann H. OR29-4 Pregnancy Outcomes in Women with Pheochromocytoma and Paraganglioma: An International Multi-Center Study Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Or29-4  1
2019 Poudel SK, Padmanabhan R, Chahal P, Sanaka M, Stevens T, Guinta K, Khorana AA, Sohal D, Eng C. Microbiome signature of bile from pancreatic and biliary tract cancer patients: A pilot study. Journal of Clinical Oncology. 37. DOI: 10.1200/Jco.2019.37.15_Suppl.E15744  1
2019 Akhavanfard S, Yehia L, Padmanabhan R, Romigh T, Ni Y, Eng C. Germline EGFR mutation and cancer predisposition in adolescent and young adult (AYA) females with adrenocortical carcinoma. Journal of Clinical Oncology. 37. DOI: 10.1200/Jco.2019.37.15_Suppl.E13014  1
2019 Pederson H, Heald B, Budd G, Bernhisel R, Cummings S, Saam J, Lancaster J, Grobmyer S, Eng C. Abstract P1-10-01: Defining the spectrum of germline variants among African American patients with triple negative breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P1-10-01  1
2019 Chong ST, Kok CY, Tan KM, Guan SP, Lai SH, Lim C, Hu J, Sturgis C, Eng C, Lam PY, Ngeow J. Abstract 2780: IL13RA2 is differentially regulated in papillary thyroid carcinoma versus follicular thyroid carcinoma Cancer Research. 79: 2780-2780. DOI: 10.1158/1538-7445.Am2019-2780  1
2019 Hoffman GS, Getz TM, Padmanabhan R, Villa-Forte A, Calabrese LH, Clifford AH, Funchain P, Sankhunny M, Perry JD, Blandford A, Kosmorsky G, Lystad L, Eng C. 184. The Microbiome Of Temporal Arteries Rheumatology. 58. DOI: 10.1093/Rheumatology/Kez060.011  1
2019 Getz TM, Hoffman GS, Padmanabhan R, Villa-Forte A, Roselli EE, Blackstone E, Johnston D, Pettersson G, Soltesz E, Svensson LG, Calabrese LH, Clifford AH, Eng C. 183. Microbiome In Aortitis Rheumatology. 58. DOI: 10.1093/Rheumatology/Kez060.010  1
2019 Shay EO, Goje O, Padmanabhan R, Eng C. 2576. The Microbiome of Recurrent Bacterial Vaginosis Compared with Asymptomatic Controls Open Forum Infectious Diseases. 6. DOI: 10.1093/Ofid/Ofz360.2254  1
2019 Shay EO, Goje O, Padmanabhan R, Eng C. 2574. Temporal Changes in the Vaginal Microbiome During Treatment for Bacterial Vaginosis: Is Lactobacillus Iners an Important Player? Open Forum Infectious Diseases. 6. DOI: 10.1093/Ofid/Ofz360.2252  1
2018 Frazier TW, Klingemier EW, Parikh S, Speer L, Strauss MS, Eng C, Hardan AY, Youngstrom EA. Development and Validation of Objective and Quantitative Eye Tracking-Based Measures of Autism Risk and Symptom Levels. Journal of the American Academy of Child and Adolescent Psychiatry. 57: 858-866. PMID 30392627 DOI: 10.1016/J.Jaac.2018.06.023  1
2018 Rivera-Muñoz EA, Milko LV, Harrison SM, Azzariti DR, Kurtz CL, Lee K, Mester JL, Weaver MA, Currey E, Craigen W, Eng C, Funke B, Hegde M, Hershberger RE, Mao R, et al. ClinGen Variant Curation Expert Panel experiences and standardized processes for disease and gene-level specification of the ACMG/AMP guidelines for sequence variant interpretation. Human Mutation. 39: 1614-1622. PMID 30311389 DOI: 10.1002/Humu.23645  1
2018 Mester JL, Ghosh R, Pesaran T, Huether R, Karam R, Hruska KS, Costa HA, Lachlan K, Ngeow J, Barnholtz-Sloan J, Sesock K, Hernandez F, Zhang L, Milko L, Plon SE, ... ... Eng C, et al. Gene-specific criteria for PTEN variant curation: Recommendations from the ClinGen PTEN Expert Panel. Human Mutation. 39: 1581-1592. PMID 30311380 DOI: 10.1002/Humu.23636  1
2018 Sankunny M, Eng C. KLLN-mediated DNA damage-induced apoptosis is associated with regulation of p53 phosphorylation and acetylation in breast cancer cells. Cell Death Discovery. 5: 31. PMID 30245854 DOI: 10.1038/S41420-018-0094-X  1
2018 Feng F, Yehia L, Ni Y, Chang YS, Jhiang SM, Eng C. A non-pump function of sodium iodide symporter in thyroid cancer via crosstalk with PTEN signaling. Cancer Research. PMID 30217930 DOI: 10.1158/0008-5472.Can-18-1954  1
2018 Foulkes WD, Bertherat J, Eng C. 65 YEARS OF THE DOUBLE HELIX: It's all in the DNA: understanding and managing endocrine neoplasms. Endocrine-Related Cancer. 25: E5-E7. PMID 29980642 DOI: 10.1530/Erc-18-0283  1
2018 Yehia L, Jindal S, Komar AA, Eng C. Non-Canonical Role of Cancer-Associated Mutant SEC23B in the Ribosome Biogenesis Pathway. Human Molecular Genetics. PMID 29893852 DOI: 10.1093/Hmg/Ddy226  1
2018 Jehi L, Yehia L, Peterson C, Niazi F, Busch R, Prayson R, Ying Z, Bingaman W, Najm I, Eng C. Preliminary report: Late seizure recurrence years after epilepsy surgery may be associated with alterations in brain tissue transcriptome. Epilepsia Open. 3: 299-304. PMID 29881812 DOI: 10.1002/epi4.12119  1
2018 Neumann HPH, Young W, Krauss T, Bayley JP, Schiavi F, Opocher G, Boedeker C, Tirosh A, Castinetti F, Ruf J, Beltsevich D, Walz MK, Groeben H, Von Dobschuetz E, Gimm O, ... ... Eng C, et al. Genetics Informs Precision Practice in the Diagnosis and Management of Pheochromocytoma. Endocrine-Related Cancer. PMID 29794110 DOI: 10.1530/Erc-18-0085  1
2018 Yehia L, Eng C. One gene - many endocrine and metabolic syndromes: PTEN-opathies and precision medicine. Endocrine-Related Cancer. PMID 29792313 DOI: 10.1530/Erc-18-0162  1
2018 Kotsopoulos J, Gronwald J, Lynch HT, Eisen A, Neuhausen SL, Tung N, Ainsworth P, Weitzel JN, Pal T, Foulkes WD, Eng C, Singer CF, Senter L, Sun P, Lubinski J, et al. Age at first full-term birth and breast cancer risk in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment. PMID 29774471 DOI: 10.1007/S10549-018-4822-Y  1
2018 Krauss T, Ferrara AM, Links TP, Wellner U, Bancos I, Kvachenyuk A, Villar Gómez de Las Heras K, Yukina M, Petrov R, Bullivant G, von Duecker L, Jadhav SS, Ploeckinger U, Welin S, Schalin-Jantti C, ... ... Eng C, et al. Preventive medicine for von Hippel-Lindau disease-associated pancreatic neuroendocrine tumors. Endocrine-Related Cancer. PMID 29748190 DOI: 10.1530/Erc-18-0100  1
2018 Yehia L, Ni Y, Sesock K, Niazi F, Fletcher B, Chen HJ, LaFramboise T, Eng C. Unexpected cancer-predisposition gene variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome patients without underlying germline PTEN mutations. Plos Genetics. 14: e1007352. PMID 29684080 DOI: 10.1371/Journal.Pgen.1007352  1
2018 Smith IN, Thacker S, Jaini R, Eng C. Dynamics and Structural Stability Effects of Germline PTEN Mutations Associated with Cancer versus Autism Phenotypes. Journal of Biomolecular Structure & Dynamics. 1-44. PMID 29663862 DOI: 10.1080/07391102.2018.1465854  1
2018 Kim SJ, Huzarski T, Gronwald J, Singer CF, Møller P, Lynch HT, Armel S, Karlan BY, Foulkes WD, Neuhausen SL, Senter L, Eisen A, Eng C, Panchal S, Pal T, et al. Prospective evaluation of body size and breast cancer risk among BRCA1 and BRCA2 mutation carriers. International Journal of Epidemiology. PMID 29547931 DOI: 10.1093/Ije/Dyy039  1
2018 Lammert J, Lubinski J, Gronwald J, Huzarski T, Armel S, Eisen A, Meschino WS, Lynch HT, Snyder C, Eng C, Olopade OI, Ginsburg O, Foulkes WD, Elser C, Cohen SA, et al. Physical activity during adolescence and young adulthood and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment. PMID 29404807 DOI: 10.1007/S10549-018-4694-1  1
2018 Pederson HJ, Gopalakrishnan D, Noss R, Yanda C, Eng C, Grobmyer SR. Impact of Multigene Panel Testing on Surgical Decision Making in Breast Cancer Patients. Journal of the American College of Surgeons. PMID 29360614 DOI: 10.1016/J.Jamcollsurg.2017.12.037  1
2018 Pederson HJ, Hussain N, Noss R, Yanda C, O'Rourke C, Eng C, Grobmyer SR. Impact of an embedded genetic counselor on breast cancer treatment. Breast Cancer Research and Treatment. PMID 29349711 DOI: 10.1007/S10549-017-4643-4  1
2018 Nizialek E, Gopalakrishnan D, Yanda C, Abbas H, Kline M, Stephens M, Grobmyer S, Eng C, Mitchell A, Pederson H, Vinayak S. Abstract P4-06-04: Germline alterations in African-American versus Caucasian patients with triple-negative breast cancer in the era of multi-gene panel testing Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P4-06-04  1
2018 Smith IN, Thacker S, Eng C. Abstract 4283: A structure network approach to predict the dynamics and structural stability effects of germline PTEN mutations associated with cancer versus autism phenotypes Cancer Research. 78: 4283-4283. DOI: 10.1158/1538-7445.Am2018-4283  1
2018 Sankunny M, Eng C. Abstract 317: Role of KLLN in DNA damage-induced apoptosis is associated with the regulation of p53 phosphorylation and acetylation in breast cancer cells Cancer Research. 78: 317-317. DOI: 10.1158/1538-7445.Am2018-317  1
2017 Bausch B, Tischler AS, Schmid KW, Leijon H, Eng C, Neumann HPH. Max Schottelius: Pioneer in Pheochromocytoma. Journal of the Endocrine Society. 1: 957-964. PMID 29264546 DOI: 10.1210/Js.2017-00208  1
2017 Yehia L, Ni Y, Eng C. Germline TTN variants are enriched in PTEN-wildtype Bannayan-Riley-Ruvalcaba syndrome. Npj Genomic Medicine. 2: 37. PMID 29263846 DOI: 10.1038/S41525-017-0039-Y  1
2017 Byrd V, Getz TM, Padmanabhan R, Arora H, Eng C. Microbiome in PTEN hamartoma tumor syndrome. Endocrine-Related Cancer. PMID 29233840 DOI: 10.1530/Erc-17-0442  1
2017 Mukherjee PK, Wang H, Retuerto M, Zhang H, Burkey B, Ghannoum MA, Eng C. Bacteriome and mycobiome associations in oral tongue cancer. Oncotarget. 8: 97273-97289. PMID 29228609 DOI: 10.18632/Oncotarget.21921  1
2017 Wang H, Altemus J, Niazi F, Green H, Calhoun BC, Sturgis C, Grobmyer SR, Eng C. Breast tissue, oral and urinary microbiomes in breast cancer. Oncotarget. 8: 88122-88138. PMID 29152146 DOI: 10.18632/Oncotarget.21490  1
2017 Procop GW, Eng C, Clifford A, Villa-Forte A, Calabrese LH, Roselli E, Svensson L, Johnston D, Pettersson G, Soltesz E, Lystad L, Perry JD, Blandford A, Wilson DA, Hoffman GS. Varicella Zoster Virus and Large Vessel Vasculitis, the Absence of an Association. Pathogens & Immunity. 2: 228-238. PMID 28758156 DOI: 10.20411/pai.v2i2.196  1
2017 Hicks JK, Shealy A, Schreiber A, Coleridge M, Noss R, Natowicz M, Moran R, Moss T, Erwin A, Eng C. Patient Decisions to Receive Secondary Pharmacogenomic Findings and Development of a Multidisciplinary Practice Model to Integrate Results Into Patient Care. Clinical and Translational Science. PMID 28749586 DOI: 10.1111/Cts.12493  1
2017 Chen HJ, Romigh T, Sesock K, Eng C. Characterization of cryptic splicing in germline PTEN intronic variants in Cowden syndrome. Human Mutation. PMID 28677221 DOI: 10.1002/Humu.23288  1
2017 Castinetti F, Maia AL, Peczkowska M, Barontini M, Hasse-Lazar K, Links TP, Toledo RA, Dvorakova S, Mian C, Bugalho MJ, Zovato S, Alevizaki M, Kvachenyuk A, Bausch B, Loli P, ... ... Eng C, et al. THE PENETRANCE OF MEN2 PHEOCHROMOCYTOMA IS NOT ONLY DETERMINED BY RET MUTATIONS. Endocrine-Related Cancer. PMID 28649091 DOI: 10.1530/Erc-17-0189  1
2017 Frazier TW, Strauss M, Klingemier EW, Zetzer EE, Hardan AY, Eng C, Youngstrom EA. A Meta-Analysis of Gaze Differences to Social and Nonsocial Information Between Individuals With and Without Autism. Journal of the American Academy of Child and Adolescent Psychiatry. 56: 546-555. PMID 28647006 DOI: 10.1016/J.Jaac.2017.05.005  1
2017 Hansen-Kiss E, Beinkampen S, Adler B, Frazier T, Prior T, Erdman S, Eng C, Herman G. A retrospective chart review of the features of PTEN hamartoma tumour syndrome in children. Journal of Medical Genetics. PMID 28526761 DOI: 10.1136/Jmedgenet-2016-104484  0.01
2017 Ngeow J, Sesock K, Eng C. Clinical Implications for Germline PTEN Spectrum Disorders. Endocrinology and Metabolism Clinics of North America. 46: 503-517. PMID 28476234 DOI: 10.1016/J.Ecl.2017.01.013  1
2017 Jaini R, Loya MG, Eng C. Immunotherapeutic target expression on breast tumors can be amplified by hormone receptor antagonism: a novel strategy for enhancing efficacy of targeted immunotherapy. Oncotarget. PMID 28430646 DOI: 10.18632/Oncotarget.15812  1
2017 Bausch B, Schiavi F, Ni Y, Welander J, Patocs A, Ngeow J, Wellner U, Malinoc A, Taschin E, Barbon G, Lanza V, Söderkvist P, Stenman A, Larsson C, Svahn F, ... ... Eng C, et al. Clinical Characterization of the Pheochromocytoma and Paraganglioma Susceptibility Genes SDHA, TMEM127, MAX, and SDHAF2 for Gene-Informed Prevention. Jama Oncology. PMID 28384794 DOI: 10.1001/Jamaoncol.2017.0223  1
2017 Yehia L, Ni Y, Eng C. Thyroglobulin in Metastatic Thyroid Cancer: Culprit or Red Herring? American Journal of Human Genetics. 100: 562-563. PMID 28257694 DOI: 10.1016/J.Ajhg.2017.01.023  1
2017 Arora HC, Eng C, Shoskes DA. Gut microbiome and chronic prostatitis/chronic pelvic pain syndrome. Annals of Translational Medicine. 5: 30. PMID 28217695 DOI: 10.21037/Atm.2016.12.32  1
2017 Wang H, Funchain P, Bebek G, Altemus J, Zhang H, Niazi F, Peterson C, Lee WT, Burkey BB, Eng C. Microbiomic differences in tumor and paired-normal tissue in head and neck squamous cell carcinomas. Genome Medicine. 9: 14. PMID 28173873 DOI: 10.1186/S13073-017-0405-5  1
2017 Yu W, Ni Y, Saji M, Ringel MD, Jaini R, Eng C. Cowden syndrome-associated germline succinate dehydrogenase complex subunit D (SDHD) variants cause PTEN-mediated down-regulation of autophagy in thyroid cancer cells. Human Molecular Genetics. PMID 28164237 DOI: 10.1093/Hmg/Ddx037  1
2017 Ngeow J, Eng C. Reply to G. Le Flahec et al. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 35: 377. PMID 28095271 DOI: 10.1200/Jco.2016.69.9405  1
2017 Mukherjee PK, Funchain P, Retuerto M, Jurevic RJ, Fowler N, Burkey B, Eng C, Ghannoum MA. Metabolomic analysis identifies differentially produced oral metabolites, including the oncometabolite 2-hydroxyglutarate, in patients with head and neck squamous cell carcinoma. Bba Clinical. 7: 8-15. PMID 28053877 DOI: 10.1016/J.Bbacli.2016.12.001  1
2017 Kotsopoulos J, Huzarski T, Gronwald J, Singer CF, Moller P, Lynch HT, Armel S, Karlan B, Foulkes WD, Neuhausen SL, Senter L, Tung N, Weitzel JN, Eisen A, Metcalfe K, ... Eng C, et al. Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers. Journal of the National Cancer Institute. 109. PMID 27601060 DOI: 10.1093/Jnci/Djw177  1
2016 Heald B, Rybicki L, Clements D, Marquard J, Mester J, Noss R, Nardini M, Polk J, Psensky B, Rigelsky C, Schreiber A, Shealy A, Smith M, Eng C. Assessment of clinical workload for general and specialty genetic counsellors at an academic medical center: a tool for evaluating genetic counselling practices. Npj Genomic Medicine. 1: 16010. PMID 29263811 DOI: 10.1038/Npjgenmed.2016.10  1
2016 Ngeow J, Eng C. Precision medicine in heritable cancer: when somatic tumour testing and germline mutations meet. Npj Genomic Medicine. 1: 15006. PMID 29263804 DOI: 10.1038/Npjgenmed.2015.6  1
2016 Ragin C, Liu JC, Jones G, Shoyele O, Sowunmi B, Kennett R, Gibbs D, Blackman E, Esan M, Brandwein MS, Devarajan K, Bussu F, Chernock R, Chien CY, Cohen MA, ... ... Eng C, et al. Prevalence of HPV infection in racial-ethnic subgroups of head and neck cancer patients. Carcinogenesis. PMID 28174904 DOI: 10.1093/carcin/bgw203  1
2016 Ragin C, Liu JC, Jones G, Shoyele O, Sowunmi B, Kennett R, Groen HJ, Gibbs D, Blackman E, Esan M, Brandwein MS, Devarajan K, Bussu F, Chernock R, Chien CY, ... ... Eng C, et al. Prevalence of HPV Infection in Racial-Ethnic Subgroups of Head and Neck Cancer Patients. Carcinogenesis. PMID 28025390 DOI: 10.1093/Carcin/Bgw203  1
2016 Ni Y, Seballos S, Fletcher B, Romigh T, Yehia L, Mester J, Senter L, Niazi F, Saji M, Ringel MD, LaFramboise T, Eng C. Germline Compound Heterozygous Poly-glutamine Deletion in USF3 May Be Involved in Predisposition to Heritable and Sporadic Epithelial Thyroid Carcinoma. Human Molecular Genetics. PMID 28011713 DOI: 10.1093/Hmg/Ddw382  1
2016 Marsh DJ, Eng C. Lessons learnt from outstanding mid-career women in endocrine cancer research. Endocrine-Related Cancer. 23: E5-E7. PMID 27935806 DOI: 10.1530/Erc-16-0406  1
2016 Colby S, Yehia L, Niazi F, Chen J, Ni Y, Mester JL, Eng C. Exome sequencing reveals germline gain-of-function EGFR mutation in an adult with Lhermitte-Duclos disease. Cold Spring Harbor Molecular Case Studies. 2: a001230. PMID 27900366 DOI: 10.1101/mcs.a001230  1
2016 Chen HH, Händel N, Ngeow J, Muller J, Hühn M, Yang HT, Heindl M, Berbers RM, Hegazy AN, Kionke J, Yehia L, Sack U, Bläser F, Rensing-Ehl A, Reifenberger J, ... ... Eng C, et al. Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells. The Journal of Allergy and Clinical Immunology. PMID 27477328 DOI: 10.1016/J.Jaci.2016.03.059  1
2016 Svensson L, Arafat A, Roselli EE, Idrees JJ, Clifford A, Tan C, Hoffman G, Eng C, Langford CA, Rodriguez ER, Gornik HL, Blackstone EH, Sabik JF, Lytle BW. Erratum: Inflammatory disease of the aorta: Patterns and classification of giant cell aortitis, Takayasu arteritis, and nonsyndromic aortitis (Journal of Thoracic and Cardiovascular Surgery (2015) 149 (S170-S175)) The Journal of Thoracic and Cardiovascular Surgery. 152. PMID 27343932 DOI: 10.1016/J.Jtcvs.2016.04.009  1
2016 Hicks JK, Stowe D, Willner MA, Wai M, Daly T, Gordon SM, Lashner BA, Parikh S, White R, Teng K, Moss T, Erwin A, Chalmers J, Eng C, Knoer S. Implementation of Clinical Pharmacogenomics within a Large Health System: From Electronic Health Record Decision Support to Consultation Services. Pharmacotherapy. PMID 27312955 DOI: 10.1002/Phar.1786  1
2016 Ngeow J, Eng C. Mismatch Repair Deficiency in Colorectal Cancers: Is Somatic Genomic Testing the Grab-Bag for All Answers? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27161963 DOI: 10.1200/Jco.2016.66.7766  1
2016 Shoskes DA, Altemus J, Polackwich AS, Tucky B, Wang H, Eng C. Response. Urology. PMID 27138265 DOI: 10.1016/j.urology.2016.04.029  1
2016 Nielsen SM, Rhodes L, Blanco I, Chung WK, Eng C, Maher ER, Richard S, Giles RH. Von Hippel-Lindau Disease: Genetics and Role of Genetic Counseling in a Multiple Neoplasia Syndrome. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27114602 DOI: 10.1200/Jco.2015.65.6140  1
2016 Ngeow J, Eng C. Germline PTEN Mutation Analysis for PTEN Hamartoma Tumor Syndrome. Methods in Molecular Biology (Clifton, N.J.). 1388: 63-73. PMID 27033071 DOI: 10.1007/978-1-4939-3299-3_6  1
2016 Frazier TW, Klingemier EW, Beukemann M, Speer L, Markowitz L, Parikh S, Wexberg S, Giuliano K, Schulte E, Delahunty C, Ahuja V, Eng C, Manos MJ, Hardan AY, Youngstrom EA, et al. Development of an Objective Autism Risk Index Using Remote Eye Tracking. Journal of the American Academy of Child and Adolescent Psychiatry. 55: 301-9. PMID 27015721 DOI: 10.1016/J.Jaac.2016.01.011  1
2016 Shoskes DA, Altemus J, Polackwich AS, Tucky B, Wang H, Eng C. The Urinary Microbiome Differs Significantly between Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Controls as Well as between Patients with Different Clinical Phenotypes. Urology. PMID 26970449 DOI: 10.1016/J.Urology.2016.02.043  1
2016 Shoskes DA, Wang H, Polackwich AS, Tucky B, Altemus J, Eng C. Analysis of Gut Microbiome Reveals Significant Differences Between Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Controls. The Journal of Urology. PMID 26930255 DOI: 10.1016/J.Juro.2016.02.2959  1
2016 He X, Thacker S, Romigh T, Yu Q, Frazier TW, Eng C. Erratum to: Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits. Molecular Autism. 7: 14. PMID 26843920 DOI: 10.1186/S13229-016-0075-Y  1
2016 Ngeow J, Eng C. HABP2 in Familial Non-medullary Thyroid Cancer: Will the Real Mutation Please Stand Up? Journal of the National Cancer Institute. 108. PMID 26832774 DOI: 10.1093/Jnci/Djw013  1
2016 Kotsopoulos J, Huzarski T, Gronwald J, Moller P, Lynch HT, Neuhausen SL, Senter L, Demsky R, Foulkes WD, Eng C, Karlan B, Tung N, Singer CF, Sun P, Lubinski J, et al. Hormone replacement therapy after menopause and risk of breast cancer in BRCA1 mutation carriers: a case-control study. Breast Cancer Research and Treatment. PMID 26780555 DOI: 10.1007/S10549-016-3685-3  1
2016 Ngeow J, Eng C. Rectal Cancer: Age Matters in the Affairs of Stage. Journal of the National Cancer Institute. 108. PMID 26719885 DOI: 10.1093/Jnci/Djv325  1
2016 Nizialek EA, Sankunny M, Niazi F, Eng C. Cancer-predisposition gene KLLN maintains pericentric H3K9 trimethylation protecting genomic stability. Nucleic Acids Research. 44: 3586-94. PMID 26673699 DOI: 10.1093/Nar/Gkv1481  1
2016 Ager C, Reilley M, Nicholas C, Bartkowiak T, Jaiswal A, Curran M, Albershardt TC, Bajaj A, Archer JF, Reeves RS, Ngo LY, Berglund P, ter Meulen J, Denis C, Ghadially H, ... ... Eng C, et al. 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two Journal For Immunotherapy of Cancer. 4. DOI: 10.1186/S40425-016-0173-6  1
2016 Sankunny M, Nizialek E, Niazi F, Eng C. Abstract 3596: KLLN protects genomic stability by maintaining H3K9 trimethylation (H3K9me3) at the pericentric heterochromatin Cancer Research. 76: 3596-3596. DOI: 10.1158/1538-7445.Am2016-3596  1
2016 Ikeda Y, Kiyotani K, Yew PY, Kato T, Tamura K, Yap KL, Mester JL, Nielsen SH, Raymon GH, Eng C, Nakamura Y. Abstract 3480: Germline PARP4 mutations in patients with primary thyroid and breast cancers Cancer Research. 76: 3480-3480. DOI: 10.1158/1538-7445.Am2016-3480  1
2016 Karagkounis G, Heald B, Liska D, Plesec T, Eng C, Church JM, Kalady MF. Clinical Implications of Microsatellite Instability in Rectal Cancer Journal of the American College of Surgeons. 223. DOI: 10.1016/J.Jamcollsurg.2016.06.073  1
2015 Ngeow J, Sesock K, Eng C. Breast cancer risk and clinical implications for germline PTEN mutation carriers. Breast Cancer Research and Treatment. PMID 26700035 DOI: 10.1007/S10549-015-3665-Z  1
2015 Ikeda Y, Kiyotani K, Yew PY, Kato T, Tamura K, Yap KL, Nielsen S, Mester J, Eng C, Nakamura Y, Grogan RH. Germline PARP4 mutations in patients with primary thyroid and breast cancers. Endocrine-Related Cancer. PMID 26699384 DOI: 10.1530/Erc-15-0359  1
2015 Gronwald J, Glass K, Rosen B, Karlan B, Tung N, Neuhausen SL, Moller P, Ainsworth P, Sun P, Narod SA, Lubinski J, Kotsopoulos J. Treatment of infertility does not increase the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation. Fertility and Sterility. PMID 26698676 DOI: 10.1016/J.Fertnstert.2015.11.034  1
2015 Heald B, Burke CA, Kalady M, Eng C. ACG Guidelines on Management of PTEN-Hamartoma Tumor Syndrome: Does the Evidence Support so Much so Young? The American Journal of Gastroenterology. 110: 1733-4. PMID 26673503 DOI: 10.1038/Ajg.2015.368  1
2015 He X, Thacker S, Romigh T, Yu Q, Frazier TW, Eng C. Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits. Molecular Autism. 6: 63. PMID 26579216 DOI: 10.1186/S13229-015-0056-6  1
2015 Yehia L, Niazi F, Ni Y, Ngeow J, Sankunny M, Liu Z, Wei W, Mester JL, Keri RA, Zhang B, Eng C. Germline Heterozygous Variants in SEC23B Are Associated with Cowden Syndrome and Enriched in Apparently Sporadic Thyroid Cancer. American Journal of Human Genetics. 97: 661-676. PMID 26522472 DOI: 10.1016/J.Ajhg.2015.10.001  1
2015 Frazier TW, Youngstrom EA, Hardan AY, Georgiades S, Constantino JN, Eng C. Quantitative autism symptom patterns recapitulate differential mechanisms of genetic transmission in single and multiple incidence families. Molecular Autism. 6: 58. PMID 26512313 DOI: 10.1186/S13229-015-0050-Z  1
2015 Semple J, Metcalfe KA, Lubinski J, Huzarski T, Gronwald J, Armel S, Lynch HT, Karlan B, Foulkes W, Singer CF, Neuhausen SL, Eng C, Iqbal J, Narod SA. Does the age of breast cancer diagnosis in first-degree relatives impact on the risk of breast cancer in BRCA1 and BRCA2 mutation carriers? Breast Cancer Research and Treatment. 154: 163-9. PMID 26467043 DOI: 10.1007/S10549-015-3596-8  1
2015 Yamazaki K, Eng C, Kuznetsov SA, Reinisch J, Yamashita DD, Walker J, Cheung C, Robey PG, Yen SL. Missense mutation in the PTEN promoter of a patient with hemifacial hyperplasia. Bonekey Reports. 4: 654. PMID 26229595 DOI: 10.1038/Bonekey.2015.21  0.01
2015 Ngeow J, Liu C, Zhou K, Frick KD, Matchar DB, Eng C. Detecting Germline PTEN Mutations Among At-Risk Patients With Cancer: An Age- and Sex-Specific Cost-Effectiveness Analysis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 2537-44. PMID 26169622 DOI: 10.1200/Jco.2014.60.3456  1
2015 Ngeow J, Yu W, Yehia L, Niazi F, Chen J, Tang X, Heald B, Lei J, Romigh T, Tucker-Kellogg L, Lim KH, Song H, Eng C. Exome Sequencing Reveals Germline SMAD9 Mutation that Reduces PTEN Expression and is Associated with Hamartomatous Polyposis and Gastrointestinal Ganglioneuromas. Gastroenterology. PMID 26122142 DOI: 10.1053/J.Gastro.2015.06.027  1
2015 Ngeow J, Eng C. New Genetic and Genomic Approaches After the Genome-wide Association Study Era--Back to the Future. Gastroenterology. 149: 1138-41. PMID 26073374 DOI: 10.1053/J.Gastro.2015.05.060  1
2015 Sutton J, Orloff MS, Michener C, Chiesa-Vottero A, Prayson R, Nowacki AS, Eng C. Association of specific PTEN/10q haplotypes with endometrial cancer phenotypes in African-American and European American women. Gynecologic Oncology. PMID 26026735 DOI: 10.1016/J.Ygyno.2015.05.024  1
2015 Toledo RA, Maciel RM, Erlic Z, Lourenço DM, Cerutti JM, Eng C, Neumann HP, Toledo SP. RET Y791F Variant Does Not Increase the Risk for Medullary Thyroid Carcinoma. Thyroid : Official Journal of the American Thyroid Association. 25: 973-4. PMID 25950813 DOI: 10.1089/Thy.2015.0168  1
2015 Tilot AK, Frazier TW, Eng C. Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 609-19. PMID 25916396 DOI: 10.1007/S13311-015-0356-8  1
2015 Bausch B, Wellner U, Peyre M, Boedeker CC, Hes FJ, Anglani M, de Campos JM, Kanno H, Maher ER, Krauss T, Sansó G, Barontini M, Letizia C, Hader C, Schiavi F, ... ... Eng C, et al. Characterization of endolymphatic sac tumors and von Hippel-Lindau disease in the International Endolymphatic Sac Tumor Registry. Head & Neck. PMID 25867206 DOI: 10.1002/Hed.24067  1
2015 Segev Y, Rosen B, Lubinski J, Gronwald J, Lynch HT, Moller P, Kim-Sing C, Ghadirian P, Karlan B, Eng C, Gilchrist D, Neuhausen SL, Eisen A, Friedman E, Euhus D, et al. Risk factors for endometrial cancer among women with a BRCA1 or BRCA2 mutation: a case control study. Familial Cancer. PMID 25838159 DOI: 10.1007/S10689-015-9798-8  1
2015 Tilot AK, Bebek G, Niazi F, Altemus JB, Romigh T, Frazier TW, Eng C. Neural transcriptome of constitutional Pten dysfunction in mice and its relevance to human idiopathic autism spectrum disorder. Molecular Psychiatry. PMID 25754085 DOI: 10.1038/Mp.2015.17  1
2015 Xekouki P, Szarek E, Bullova P, Giubellino A, Quezado M, Mastroyannis SA, Mastorakos P, Wassif CA, Raygada M, Rentia N, Dye L, Cougnoux A, Koziol D, Sierra Mde L, Lyssikatos C, ... ... Eng C, et al. Pituitary adenoma with paraganglioma/pheochromocytoma (3PAs) and succinate dehydrogenase defects in humans and mice. The Journal of Clinical Endocrinology and Metabolism. 100: E710-9. PMID 25695889 DOI: 10.1210/Jc.2014-4297  1
2015 Ni Y, Seballos S, Ganapathi S, Gurin D, Fletcher B, Ngeow J, Nagy R, Kloos RT, Ringel MD, LaFramboise T, Eng C. Germline and somatic SDHx alterations in apparently sporadic differentiated thyroid cancer. Endocrine-Related Cancer. 22: 121-30. PMID 25694510 DOI: 10.1530/Erc-14-0537  1
2015 Nizialek EA, Mester JL, Dhiman VK, Smiraglia DJ, Eng C. KLLN epigenotype-phenotype associations in Cowden syndrome. European Journal of Human Genetics : Ejhg. 23: 1538-43. PMID 25669429 DOI: 10.1038/Ejhg.2015.8  1
2015 Mester JL, Mercer M, Goldenberg A, Moore RA, Eng C, Sharp RR. Communicating with biobank participants: preferences for receiving and providing updates to researchers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 24: 708-12. PMID 25597748 DOI: 10.1158/1055-9965.Epi-13-1375  1
2015 von Dobschuetz E, Leijon H, Schalin-Jäntti C, Schiavi F, Brauckhoff M, Peczkowska M, Spiazzi G, Demattè S, Cecchini ME, Sartorato P, Krajewska J, Hasse-Lazar K, Roszkowska-Purska K, Taschin E, Malinoc A, ... Eng C, et al. A registry-based study of thyroid paraganglioma: histological and genetic characteristics. Endocrine-Related Cancer. 22: 191-204. PMID 25595276 DOI: 10.1530/Erc-14-0558  1
2015 Ngeow J, Eng C. PTEN hamartoma tumor syndrome: clinical risk assessment and management protocol. Methods (San Diego, Calif.). 77: 11-9. PMID 25461771 DOI: 10.1016/J.Ymeth.2014.10.011  1
2015 Mahdi H, Mester JL, Nizialek EA, Ngeow J, Michener C, Eng C. Germline PTEN, SDHB-D, and KLLN alterations in endometrial cancer patients with Cowden and Cowden-like syndromes: an international, multicenter, prospective study. Cancer. 121: 688-96. PMID 25376524 DOI: 10.1002/Cncr.29106  1
2015 Svensson LG, Arafat A, Roselli EE, Idrees J, Clifford A, Tan C, Hoffman G, Eng C, Langford C, Rodriguez ER, Gornik HL, Blackstone E, Sabik JF, Lytle BW. Inflammatory disease of the aorta: patterns and classification of giant cell aortitis, Takayasu arteritis, and nonsyndromic aortitis. The Journal of Thoracic and Cardiovascular Surgery. 149: S170-5. PMID 25218529 DOI: 10.1016/J.Jtcvs.2014.08.003  1
2015 Yu W, He X, Ni Y, Ngeow J, Eng C. Cowden syndrome-associated germline SDHD variants alter PTEN nuclear translocation through SRC-induced PTEN oxidation. Human Molecular Genetics. 24: 142-53. PMID 25149476 DOI: 10.1093/Hmg/Ddu425  1
2015 Mester J, Eng C. Cowden syndrome: Recognizing and managing a not-so-rare hereditary cancer syndrome Journal of Surgical Oncology. 111: 125-130. PMID 25132236 DOI: 10.1002/Jso.23735  1
2015 Wu L, de Bruin A, Wang H, Simmons T, Cleghorn W, Goldenberg LE, Sites E, Sandy A, Trimboli A, Fernandez SA, Eng C, Shapiro C, Leone G. Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis Oncogene. 34: 119-128. PMID 24276244 DOI: 10.1038/Onc.2013.511  1
2015 Xekouki P, Szarek E, Bullova P, Giubellino A, Quezado M, Mastroyannis SA, Mastorakos P, Wassif CA, Raygada M, Rentia N, Dye L, Cougnoux A, Koziol D, De La Luz Sierra M, Lyssikatos C, ... Eng C, et al. Pituitary adenoma with paraganglioma/pheochromocytoma (3PAs) and succinate dehydrogenase defects in humans and mice Journal of Clinical Endocrinology and Metabolism. 100: E710-E719. DOI: 10.1210/jc.2014-4297  1
2015 Sathyan P, Gurnani P, Lasecki D, Hicks K, Eng C, Rosenblatt KP. Role of combined germline pharmacogenomic and somatic genomic analysis in personalized cancer therapy: Non-small cell lung cancer (NSCLC) case study. Journal of Clinical Oncology. 33. DOI: 10.1200/Jco.2015.33.15_Suppl.E18551  0.01
2015 Funchain P, Sohal D, Khorana AA, Abraham J, Pennell NA, Rini BI, Dreicer R, Bolwell BJ, Eng C. Hereditary implications of somatic tumor testing. Journal of Clinical Oncology. 33: 1523-1523. DOI: 10.1200/Jco.2015.33.15_Suppl.1523  1
2015 Ngeow J, Liu C, Zhou K, Frick K, Matchar DB, Eng C. Abstract 3732: Detecting germline PTEN mutations among at-risk cancer patients: An age and gender-specific cost effectiveness analysis Cancer Research. 75: 3732-3732. DOI: 10.1158/1538-7445.Am2015-3732  1
2015 Nizialek EA, Sankunny M, Niazi F, Eng C. Cancer-predisposition gene KLLN maintains pericentric H3K9 trimethylation protecting genomic stability Nucleic Acids Research. 44: 3586-3594. DOI: 10.1093/nar/gkv1481  1
2015 Heald B, Burke CA, Kalady M, Eng C. ACG guidelines on management of PTEN-hamartoma tumor syndrome: Does the evidence support so much so young? American Journal of Gastroenterology. 110: 1733-1734. DOI: 10.1038/ajg.2015.368  1
2015 Nakashima MO, Shetty S, Chicka M, Flagg A, Eng C, Cotta CV. Transient abnormal myelopoiesis of a newborn not associated with chromosome 21 abnormalities or GATA1 mutations Pediatric Blood and Cancer. 62: 353-355. DOI: 10.1002/pbc.25226  1
2014 Ngeow J, Eng C. Whole-genome sequencing: not yet making the clinical grade. Personalized Medicine. 11: 471-475. PMID 29758773 DOI: 10.2217/Pme.14.32  1
2014 Ha D, Mester J, Eng C, Farha S. Pulmonary arterial hypertension in a patient with Cowden syndrome and the PTEN mutation. Pulmonary Circulation. 4: 728-31. PMID 25610608 DOI: 10.1086/678552  1
2014 Doerr M, Edelman E, Gabitzsch E, Eng C, Teng K. Formative evaluation of clinician experience with integrating family history-based clinical decision support into clinical practice. Journal of Personalized Medicine. 4: 115-36. PMID 25563219 DOI: 10.3390/Jpm4020115  1
2014 Frazier TW, Embacher R, Tilot AK, Koenig K, Mester J, Eng C. Molecular and phenotypic abnormalities in individuals with germline heterozygous PTEN mutations and autism. Molecular Psychiatry. PMID 25288137 DOI: 10.1038/Mp.2014.125  1
2014 Nakashima MO, Shetty S, Chicka M, Flagg A, Eng C, Cotta CV. Transient abnormal myelopoiesis of a newborn not associated with chromosome 21 abnormalities or GATA1 mutations. Pediatric Blood & Cancer. PMID 25175265 DOI: 10.1002/Pbc.25226  0.01
2014 Stoffel EM, Eng C. Exome sequencing in familial colorectal cancer: Searching for needles in haystacks Gastroenterology. 147: 554-556. PMID 25075943 DOI: 10.1053/J.Gastro.2014.07.031  1
2014 Ngeow J, Eng C. TERT and BRAF in thyroid cancer: teaming up for trouble. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 2683-4. PMID 25024083 DOI: 10.1200/Jco.2014.56.5614  1
2014 Ngeow J, Eng C. BluepRINT for moderate-to-low penetrance cancer susceptibility genes needed: breast cancer and beyond. Cancer Discovery. 4: 762-3. PMID 25002613 DOI: 10.1158/2159-8290.Cd-14-0498  1
2014 Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, et al. A unified nomenclature and amino acid numbering for human PTEN. Science Signaling. 7: pe15. PMID 24985344 DOI: 10.1126/Scisignal.2005560  1
2014 Busch RM, Najm I, Hermann BP, Eng C. Genetics of cognition in epilepsy. Epilepsy & Behavior : E&B. 41: 297-306. PMID 24973143 DOI: 10.1016/J.Yebeh.2014.05.026  1
2014 Wang Y, Roma A, Nolley R, Abdul-Karim F, Peehl DM, Eng C. Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma. Endocrine-Related Cancer. 21: 579-86. PMID 24972837 DOI: 10.1530/Erc-14-0148  1
2014 Gronwald J, Robidoux A, Kim-Sing C, Tung N, Lynch HT, Foulkes WD, Manoukian S, Ainsworth P, Neuhausen SL, Demsky R, Eisen A, Singer CF, Saal H, Senter L, Eng C, et al. Duration of tamoxifen use and the risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment. 146: 421-7. PMID 24951267 DOI: 10.1007/S10549-014-3026-3  1
2014 Moline J, Eng C. Equality in Lynch syndrome screening: Why should we hold patients with endometrial cancer to a different standard? Journal of Clinical Oncology. 32: 2277. PMID 24912902 DOI: 10.1200/Jco.2014.55.3602  1
2014 Tan MH, Eng C. RE: Cowden syndrome and PTEN hamartoma tumor syndrome: Systematic review and revised diagnostic criteria Journal of the National Cancer Institute. 106. PMID 24899679 DOI: 10.1093/Jnci/Dju130  1
2014 Stechschulte LA, Wuescher L, Marino JS, Hill JW, Eng C, Hinds TD. Glucocorticoid receptor β stimulates Akt1 growth pathway by attenuation of PTEN. The Journal of Biological Chemistry. 289: 17885-94. PMID 24817119 DOI: 10.1074/Jbc.M113.544072  1
2014 Ngeow J, Stanuch K, Mester JL, Barnholtz-Sloan JS, Eng C. Second malignant neoplasms in patients with Cowden syndrome with underlying germline PTEN mutations. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 1818-24. PMID 24778394 DOI: 10.1200/Jco.2013.53.6656  1
2014 Castinetti F, Qi XP, Walz MK, Maia AL, Sansó G, Peczkowska M, Hasse-Lazar K, Links TP, Dvorakova S, Toledo RA, Mian C, Bugalho MJ, Wohllk N, Kollyukh O, Canu L, ... ... Eng C, et al. Outcomes of adrenal-sparing surgery or total adrenalectomy in phaeochromocytoma associated with multiple endocrine neoplasia type 2: an international retrospective population-based study. The Lancet. Oncology. 15: 648-55. PMID 24745698 DOI: 10.1016/S1470-2045(14)70154-8  1
2014 Ngeow J, Ni Y, Tohme R, Song Chen F, Bebek G, Eng C. Germline alterations in RASAL1 in Cowden syndrome patients presenting with follicular thyroid cancer and in individuals with apparently sporadic epithelial thyroid cancer. The Journal of Clinical Endocrinology and Metabolism. 99: E1316-21. PMID 24712574 DOI: 10.1210/Jc.2014-1225  1
2014 Mutter GL, Monte NM, Neuberg D, Ferenczy A, Eng C. Emergence, involution, and progression to carcinoma of mutant clones in normal endometrial tissues Cancer Research. 74: 2796-2802. PMID 24662919 DOI: 10.1158/0008-5472.Can-14-0108  1
2014 Heald B, Eng C. Time studies of the tasks associated with comprehensive cancer genetics counseling: Reply Jnccn Journal of the National Comprehensive Cancer Network. 12: 303. PMID 24616535 DOI: 10.6004/Jnccn.2014.0045  1
2014 Frazier TW, Thompson L, Youngstrom EA, Law P, Hardan AY, Eng C, Morris N. A twin study of heritable and shared environmental contributions to autism. Journal of Autism and Developmental Disorders. 44: 2013-25. PMID 24604525 DOI: 10.1007/S10803-014-2081-2  1
2014 Tilot AK, Gaugler MK, Yu Q, Romigh T, Yu W, Miller RH, Frazier TW, Eng C. Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production. Human Molecular Genetics. 23: 3212-27. PMID 24470394 DOI: 10.1093/Hmg/Ddu031  1
2014 Kotsopoulos J, Lubinski J, Moller P, Lynch HT, Singer CF, Eng C, Neuhausen SL, Karlan B, Kim-Sing C, Huzarski T, Gronwald J, McCuaig J, Senter L, Tung N, Ghadirian P, et al. Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutation carriers. Breast Cancer Research and Treatment. 143: 579-86. PMID 24458845 DOI: 10.1007/S10549-013-2823-4  1
2014 Smith M, Mester J, Eng C. How to spot heritable breast cancer: a primary care physician's guide. Cleveland Clinic Journal of Medicine. 81: 31-40. PMID 24391105 DOI: 10.3949/Ccjm.81A.13051  1
2014 Wang Y, Yu Q, He X, Romigh T, Altemus J, Eng C. Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation. Molecular Cancer Therapeutics. 13: 517-27. PMID 24356815 DOI: 10.1158/1535-7163.Mct-13-0655  1
2014 Henderson CJ, Ngeow J, Collins MH, Martin LJ, Putnam PE, Abonia JP, Marsolo K, Eng C, Rothenberg ME. Increased prevalence of eosinophilic gastrointestinal disorders in pediatric PTEN hamartoma tumor syndromes. Journal of Pediatric Gastroenterology and Nutrition. 58: 553-60. PMID 24345843 DOI: 10.1097/Mpg.0000000000000253  1
2014 Bausch B, Wellner U, Bausch D, Schiavi F, Barontini M, Sanso G, Walz MK, Peczkowska M, Weryha G, Dall'igna P, Cecchetto G, Bisogno G, Moeller LC, Bockenhauer D, Patocs A, ... Eng C, et al. Long-term prognosis of patients with pediatric pheochromocytoma. Endocrine-Related Cancer. 21: 17-25. PMID 24169644 DOI: 10.1530/Erc-13-0415  1
2014 Frazier TW, Youngstrom EA, Embacher R, Hardan AY, Constantino JN, Law P, Findling RL, Eng C. Demographic and clinical correlates of autism symptom domains and autism spectrum diagnosis. Autism : the International Journal of Research and Practice. 18: 571-82. PMID 24104512 DOI: 10.1177/1362361313481506  1
2014 Hobert JA, Embacher R, Mester JL, Frazier TW, Eng C. Biochemical screening and PTEN mutation analysis in individuals with autism spectrum disorders and macrocephaly. European Journal of Human Genetics : Ejhg. 22: 273-6. PMID 23695273 DOI: 10.1038/Ejhg.2013.114  1
2014 Ngeow J, Eng C. Whole-genome sequencing: Not yet making the clinical grade Personalized Medicine. 11: 471-475. DOI: 10.2217/pme.14.32  1
2014 Mahdi H, Woessner JR, Buechel M, Moline J, Eng C, Michener C, Rose PG. Outcome and response to neoadjuvant chemotherapy in patients with advanced stage Müllerian cancer in BRCA1/2 mutation-positive compared to mutation-negative women Gynecologic Oncology. 133: 86. DOI: 10.1016/J.Ygyno.2014.03.230  1
2014 Mahdi H, Mester JL, Nizialek E, Michener C, Eng C. Germline SDHB/C/D variation and KLLN promoter methylation in endometrial cancer patients with Cowden and Cowden-like syndrome Gynecologic Oncology. 133: 78. DOI: 10.1016/J.Ygyno.2014.03.210  1
2014 Mahdi H, Mester JL, Michener C, Eng C. Prevalence and clinical predictors of germline PTEN mutation in endometrial cancer patients with Cowden and Cowden-like syndrome Gynecologic Oncology. 133: 77-78. DOI: 10.1016/J.Ygyno.2014.03.209  1
2013 Ngeow J, Eng C. Research Highlights: Highlights from the latest articles in personalized medicine. Personalized Medicine. 10: 231-233. PMID 29768739 DOI: 10.2217/Pme.13.15  1
2013 Ngeow J, Nizialek E, Eng C. Into the eye of the storm: breast cancer's somatic mutation landscape points to DNA damage and repair. Translational Cancer Research. 2: 59-61. PMID 26613077 DOI: 10.21037/1116  1
2013 Eng C. Molecular genetics to genomic medicine practice: at the heart of value-based delivery of healthcare. Molecular Genetics & Genomic Medicine. 1: 4-6. PMID 24498597 DOI: 10.1002/Mgg3.8  0.01
2013 Ngeow J, Eng C. RASAL1 in thyroid cancer: wisdom from an old foe. Journal of the National Cancer Institute. 105: 1597-9. PMID 24136888 DOI: 10.1093/Jnci/Djt291  1
2013 Valentini A, Lubinski J, Byrski T, Ghadirian P, Moller P, Lynch HT, Ainsworth P, Neuhausen SL, Weitzel J, Singer CF, Olopade OI, Saal H, Lyonnet DS, Foulkes WD, Kim-Sing C, ... ... Eng C, et al. The impact of pregnancy on breast cancer survival in women who carry a BRCA1 or BRCA2 mutation. Breast Cancer Research and Treatment. 142: 177-85. PMID 24136669 DOI: 10.1007/S10549-013-2729-1  1
2013 Mester JL, Moore RA, Eng C. PTEN germline mutations in patients initially tested for other hereditary cancer syndromes: would use of risk assessment tools reduce genetic testing? The Oncologist. 18: 1083-90. PMID 24037976 DOI: 10.1634/Theoncologist.2013-0174  1
2013 Heald B, Gustafson S, Mester J, Arscott P, Lynch K, Moline J, Eng C. A time study of cancer genetic counselors using a genetic counselor-only patient care model versus a traditional combined genetic counselor plus medical geneticist care model. Journal of the National Comprehensive Cancer Network : Jnccn. 11: 1076-81. PMID 24029123 DOI: 10.6004/Jnccn.2013.0129  1
2013 Bausch B, Jilg C, Gläsker S, Vortmeyer A, Lützen N, Anton A, Eng C, Neumann HP. Renal cancer in von Hippel-Lindau disease and related syndromes. Nature Reviews. Nephrology. 9: 529-38. PMID 23897319 DOI: 10.1038/Nrneph.2013.144  1
2013 Hopman SM, Merks JH, de Borgie CA, Aalfs CM, Biesecker LG, Cole T, Eng C, Legius E, Maher ER, van Noesel MM, Verloes A, Viskochil DH, Wagner A, Weksberg R, Caron HN, et al. The development of a clinical screening instrument for tumour predisposition syndromes in childhood cancer patients. European Journal of Cancer (Oxford, England : 1990). 49: 3247-54. PMID 23855994 DOI: 10.1016/J.Ejca.2013.06.015  1
2013 Semple J, Metcalfe KA, Lynch HT, Kim-Sing C, Senter L, Pal T, Ainsworth P, Lubinski J, Tung N, Eng C, Gilchrist D, Blum J, Neuhausen SL, Singer CF, Ghadirian P, et al. International rates of breast reconstruction after prophylactic mastectomy in BRCA1 and BRCA2 mutation carriers. Annals of Surgical Oncology. 20: 3817-22. PMID 23740344 DOI: 10.1245/S10434-013-3040-4  1
2013 Ngeow J, Eng C. Population-based universal screening for Lynch syndrome: ready, set... How? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2527-9. PMID 23733783 DOI: 10.1200/Jco.2013.50.4373  1
2013 Funchain P, Eng C. Hunting for cancer in the microbial jungle. Genome Medicine. 5: 42. PMID 23731547 DOI: 10.1186/Gm446  1
2013 Farley MN, Schmidt LS, Mester JL, Peña-Llopis S, Pavia-Jimenez A, Christie A, Vocke CD, Ricketts CJ, Peterson J, Middelton L, Kinch L, Grishin N, Merino MJ, Metwalli AR, Xing C, ... ... Eng C, et al. A novel germline mutation in BAP1 predisposes to familial clear-cell renal cell carcinoma. Molecular Cancer Research : McR. 11: 1061-71. PMID 23709298 DOI: 10.1158/1541-7786.Mcr-13-0111  1
2013 Mester J, Eng C. When overgrowth bumps into cancer: the PTEN-opathies. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 163: 114-21. PMID 23613428 DOI: 10.1002/ajmg.c.31364  1
2013 Moline J, Mahdi H, Yang B, Biscotti C, Roma AA, Heald B, Rose PG, Michener C, Eng C. Implementation of tumor testing for lynch syndrome in endometrial cancers at a large academic medical center. Gynecologic Oncology. 130: 121-6. PMID 23612316 DOI: 10.1016/J.Ygyno.2013.04.022  1
2013 Mester J, Eng C. When Overgrowth Bumps Into Cancer: The PTEN-Opathies. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. PMID 23576530 DOI: 10.1002/J.1552-4876.2013.31364.X  1
2013 He X, Arrotta N, Radhakrishnan D, Wang Y, Romigh T, Eng C. Cowden syndrome-related mutations in PTEN associate with enhanced proteasome activity. Cancer Research. 73: 3029-40. PMID 23475934 DOI: 10.1158/0008-5472.Can-12-3811  1
2013 Busch RM, Chapin JS, Mester J, Ferguson L, Haut JS, Frazier TW, Eng C. Cognitive characteristics of PTEN hamartoma tumor syndromes. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 548-53. PMID 23470840 DOI: 10.1038/Gim.2013.1  1
2013 Zhang L, Orloff MS, Reber S, Li S, Zhao Y, Eng C. cgaTOH: extended approach for identifying tracts of homozygosity. Plos One. 8: e57772. PMID 23469237 DOI: 10.1371/Journal.Pone.0057772  1
2013 Nizialek EA, Peterson C, Mester JL, Downes-Kelly E, Eng C. Germline and somatic KLLN alterations in breast cancer dysregulate G2 arrest. Human Molecular Genetics. 22: 2451-61. PMID 23446638 DOI: 10.1093/Hmg/Ddt097  1
2013 Wang Y, He X, Yu Q, Eng C. Androgen receptor-induced tumor suppressor, KLLN, inhibits breast cancer growth and transcriptionally activates p53/p73-mediated apoptosis in breast carcinomas. Human Molecular Genetics. 22: 2263-72. PMID 23418309 DOI: 10.1093/Hmg/Ddt077  1
2013 Heald B, Plesec T, Liu X, Pai R, Patil D, Moline J, Sharp RR, Burke CA, Kalady MF, Church J, Eng C. Implementation of universal microsatellite instability and immunohistochemistry screening for diagnosing lynch syndrome in a large academic medical center. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 1336-40. PMID 23401454 DOI: 10.1200/Jco.2012.45.1674  1
2013 Ngeow J, Heald B, Rybicki LA, Orloff MS, Chen JL, Liu X, Yerian L, Willis J, Lehtonen HJ, Lehtonen R, Mester JL, Moline J, Burke CA, Church J, Aaltonen LA, ... Eng C, et al. Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps. Gastroenterology. 144: 1402-9, 1409.e1-5. PMID 23399955 DOI: 10.1053/J.Gastro.2013.02.001  1
2013 Wang Y, Radhakrishnan D, He X, Peehl DM, Eng C. Transcription factor KLLN inhibits tumor growth by AR suppression, induces apoptosis by TP53/TP73 stimulation in prostate carcinomas, and correlates with cellular differentiation. The Journal of Clinical Endocrinology and Metabolism. 98: E586-94. PMID 23386643 DOI: 10.1210/Jc.2012-3490  1
2013 Granados A, Eng C, Diaz A. Brothers with germline PTEN mutations and persistent hypoglycemia, macrocephaly, developmental delay, short stature, and coagulopathy. Journal of Pediatric Endocrinology & Metabolism : Jpem. 26: 137-41. PMID 23382303 DOI: 10.1515/Jpem-2012-0227  1
2013 Wu W, Bhagat TD, Yang X, Song JH, Cheng Y, Agarwal R, Abraham JM, Ibrahim S, Bartenstein M, Hussain Z, Suzuki M, Yu Y, Chen W, Eng C, Greally J, et al. Hypomethylation of noncoding DNA regions and overexpression of the long noncoding RNA, AFAP1-AS1, in Barrett's esophagus and esophageal adenocarcinoma. Gastroenterology. 144: 956-966.e4. PMID 23333711 DOI: 10.1053/J.Gastro.2013.01.019  1
2013 Manolio TA, Chisholm RL, Ozenberger B, Roden DM, Williams MS, Wilson R, Bick D, Bottinger EP, Brilliant MH, Eng C, Frazer KA, Korf B, Ledbetter DH, Lupski JR, Marsh C, et al. Implementing genomic medicine in the clinic: the future is here. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 258-67. PMID 23306799 DOI: 10.1097/01.Ogx.0000435523.89711.77  1
2013 Neumann HP, Jilg C, Bacher J, Nabulsi Z, Malinoc A, Hummel B, Hoffmann MM, Ortiz-Bruechle N, Glasker S, Pisarski P, Neeff H, Krämer-Guth A, Cybulla M, Hornberger M, Wilpert J, ... ... Eng C, et al. Epidemiology of autosomal-dominant polycystic kidney disease: an in-depth clinical study for south-western Germany. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 28: 1472-87. PMID 23300259 DOI: 10.1093/Ndt/Gfs551  1
2013 Orloff MS, He X, Peterson C, Chen F, Chen JL, Mester JL, Eng C. Germline PIK3CA and AKT1 mutations in Cowden and Cowden-like syndromes. American Journal of Human Genetics. 92: 76-80. PMID 23246288 DOI: 10.1016/J.Ajhg.2012.10.021  1
2013 Ngeow J, Eng C. The 'in-vironment': Coming of age of microbiomics in personalized medicine Personalized Medicine. 10: 231-233. DOI: 10.2217/pme.13.15  1
2013 Ngeow JY, Mester J, Mahdi H, Yehia L, Barnholtz-Sloan J, Eng C. Second malignant neoplasms (SMN) in Cowden syndrome patients with underlying germline PTEN mutations. Journal of Clinical Oncology. 31: 1527-1527. DOI: 10.1200/Jco.2013.31.15_Suppl.1527  0.01
2013 Hopman SMJ, Merks JHM, Borgie CAJMd, Biesecker LG, Cole T, Eng C, Legius E, Maher ER, Meer CAvd, Noesel MMv, Verloes A, Viskochil DH, Wagner A, Weksberg R, Caron HN, et al. The development of a clinical screening tool for tumour predisposition syndromes in childhood cancer patients Tijdschrift Voor Kindergeneeskunde. 81: 52-52. DOI: 10.1007/S12456-013-0051-9  1
2012 Ngeow J, Eng C. Thyroid cancer genetics: how close are we to personalizing clinical management? Personalized Medicine. 9: 355-358. PMID 29776255 DOI: 10.2217/Pme.12.31  1
2012 Milas M, Mester J, Metzger R, Shin J, Mitchell J, Berber E, Siperstein AE, Eng C. Should patients with Cowden syndrome undergo prophylactic thyroidectomy? Surgery. 152: 1201-10. PMID 23158187 DOI: 10.1016/J.Surg.2012.08.055  1
2012 Neumann HP, Malinoc A, Bacher J, Nabulsi Z, Ivanovas V, Bruechle NO, Mader I, Hoffmann MM, Riegler P, Kraemer-Guth A, Burchardi C, Schaeffner E, Martin RS, Azurmendi PJ, Zerres K, ... ... Eng C, et al. Characteristics of intracranial aneurysms in the else kröner-fresenius registry of autosomal dominant polycystic kidney disease. Cerebrovascular Diseases Extra. 2: 71-9. PMID 23139683 DOI: 10.1159/000342620  1
2012 Lewis CM, Bu D, Sarode V, Robinson L, Wilson KS, Viscusi RK, Eng C, Euhus DM. The clinical consequences of hemizygosity across 2 MB of 10q23 are restricted to Cowden syndrome. Breast Cancer Research and Treatment. 136: 911-8. PMID 23132533 DOI: 10.1007/S10549-012-2322-Z  1
2012 Ngeow J, He X, Mester JL, Lei J, Romigh T, Orloff MS, Milas M, Eng C. Utility of PTEN protein dosage in predicting for underlying germline PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypes. The Journal of Clinical Endocrinology and Metabolism. 97: E2320-7. PMID 23066114 DOI: 10.1210/Jc.2012-2944  1
2012 He X, Saji M, Radhakrishnan D, Romigh T, Ngeow J, Yu Q, Wang Y, Ringel MD, Eng C. PTEN lipid phosphatase activity and proper subcellular localization are necessary and sufficient for down-regulating AKT phosphorylation in the nucleus in Cowden syndrome. The Journal of Clinical Endocrinology and Metabolism. 97: E2179-87. PMID 22962422 DOI: 10.1210/Jc.2012-1991  1
2012 Herder WWd, Eng C. Obesity, diabetes mellitus, and cancer Endocrine-Related Cancer. 19. PMID 22952202 DOI: 10.1530/Erc-12-0264  0.01
2012 Ni Y, Eng C. Vitamin E protects against lipid peroxidation and rescues tumorigenic phenotypes in cowden/cowden-like patient-derived lymphoblast cells with germline SDHx variants Clinical Cancer Research. 18: 4954-4961. PMID 22829200 DOI: 10.1158/1078-0432.Ccr-12-1055  1
2012 O'Malley M, LaGuardia L, Kalady MF, Parambil J, Heald B, Eng C, Church J, Burke CA. The prevalence of hereditary hemorrhagic telangiectasia in juvenile polyposis syndrome. Diseases of the Colon and Rectum. 55: 886-92. PMID 22810475 DOI: 10.1097/Dcr.0B013E31825Aad32  1
2012 Hopman SMJ, Rijn RRV, Eng C, Bras J, Alders M, Horst CMvd, Hennekam RCM, Merks JHM. PTEN hamartoma tumor syndrome and Gorham-Stout phenomenon. American Journal of Medical Genetics Part A. 158: 1719-1723. PMID 22628360 DOI: 10.1002/Ajmg.A.35406  1
2012 Mester J, Eng C. Estimate of de novo mutation frequency in probands with PTEN hamartoma tumor syndrome Genetics in Medicine. 14: 819-822. PMID 22595938 DOI: 10.1038/Gim.2012.51  1
2012 Kotsopoulos J, Lubinski J, Lynch HT, Kim-Sing C, Neuhausen S, Demsky R, Foulkes WD, Ghadirian P, Tung N, Ainsworth P, Senter L, Karlan B, Eisen A, Eng C, Weitzel J, et al. Oophorectomy after menopause and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers Cancer Epidemiology Biomarkers and Prevention. 21: 1089-1096. PMID 22564871 DOI: 10.1158/1055-9965.Epi-12-0201  1
2012 Doerr M, Eng C. Personalised care and the genome Bmj (Clinical Research Ed.). 344. PMID 22556053 DOI: 10.1136/Bmj.E3174  1
2012 Teng KA, Eng C. Personalizing patient care Cleveland Clinic Journal of Medicine. 79: 329-330. PMID 22550074 DOI: 10.3949/Ccjm.79A.11074  1
2012 Deschamps AM, Eng C. Engaging basic scientists in translational research. Endocrine-Related Cancer. 19: E1-3. PMID 22514111 DOI: 10.1530/Erc-12-0106  1
2012 Singh AD, Aronow ME, Sun Y, Bebek G, Saunthararajah Y, Schoenfield LR, Biscotti CV, Tubbs RR, Triozzi PL, Eng C. Chromosome 3 status in uveal melanoma: a comparison of fluorescence in situ hybridization and single-nucleotide polymorphism array. Investigative Ophthalmology & Visual Science. 53: 3331-9. PMID 22511634 DOI: 10.1167/Iovs.11-9027  1
2012 Hobin JA, Deschamps AM, Bockman R, Cohen S, Dechow P, Eng C, Galey W, Morris M, Prabhakar S, Raj U, Rubenstein P, Smith JA, Stover P, Sung N, Talman W, et al. Engaging basic scientists in translational research: identifying opportunities, overcoming obstacles. Journal of Translational Medicine. 10: 72. PMID 22500917 DOI: 10.1186/1479-5876-10-72  1
2012 Teng K, Eng C, Hess CA, Holt MA, Moran RT, Sharp RR, Traboulsi EI. Building an innovative model for personalized healthcare. Cleveland Clinic Journal of Medicine. 79: S1-9. PMID 22492701 DOI: 10.3949/Ccjm.79.S1.01  1
2012 Hesson LB, Packham D, Pontzer E, Funchain P, Eng C, Ward RL. A reinvestigation of somatic hypermethylation at the PTEN CpG island in cancer cell lines. Biological Procedures Online. 14: 5. PMID 22490388 DOI: 10.1186/1480-9222-14-5  1
2012 Kurek KC, Howard E, Tennant LB, Upton J, Alomari AI, Burrows PE, Chalache K, Harris DJ, Trenor CC, Eng C, Fishman SJ, Mulliken JB, Perez-Atayde AR, Kozakewich HP. PTEN hamartoma of soft tissue: a distinctive lesion in PTEN syndromes. The American Journal of Surgical Pathology. 36: 671-87. PMID 22446940 DOI: 10.1097/Pas.0B013E31824Dd86C  1
2012 Tuupanen S, Yan J, Turunen M, Gylfe AE, Kaasinen E, Li L, Eng C, Culver DA, Kalady MF, Pennison MJ, Pasche B, Manne U, de la Chapelle A, Hampel H, Henderson BE, et al. Characterization of the colorectal cancer-associated enhancer MYC-335 at 8q24: the role of rs67491583. Cancer Genetics. 205: 25-33. PMID 22429595 DOI: 10.1016/J.Cancergen.2012.01.005  1
2012 Kotsopoulos J, Lubinski J, Salmena L, Lynch HT, Kim-Sing C, Foulkes WD, Ghadirian P, Neuhausen SL, Demsky R, Tung N, Ainsworth P, Senter L, Eisen A, Eng C, Singer C, et al. Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers Breast Cancer Research. 14. PMID 22405187 DOI: 10.1186/Bcr3138  1
2012 Orloff MS, Zhang L, Bebek G, Eng C. Integrative genomic analysis reveals extended germline homozygosity with lung cancer risk in the PLCO cohort. Plos One. 7: e31975. PMID 22384118 DOI: 10.1371/Journal.Pone.0031975  0.01
2012 Mester JL, Zhou M, Prescott N, Eng C. Papillary Renal Cell Carcinoma is Associated with PTEN Hamartoma Tumor Syndrome Urology. 79: 1187. PMID 22381246 DOI: 10.1016/J.Urology.2011.12.025  1
2012 Malinoc A, Sullivan M, Wiech T, Kurt Werner S, Jilg C, Straeter J, Deger S, Hoffmann MM, Bosse A, Rasp G, Eng C, Neumann HP. Biallelic inactivation of the SDHC gene in renal carcinoma associated with paraganglioma syndrome type 3. Endocrine-Related Cancer. 19: 283-90. PMID 22351710 DOI: 10.1530/Erc-11-0324  1
2012 Ashida S, Orloff MS, Bebek G, Zhang L, Zheng P, Peehl DM, Eng C. Integrated analysis reveals critical genomic regions in prostate tumor microenvironment associated with clinicopathologic phenotypes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 1578-87. PMID 22275508 DOI: 10.1158/1078-0432.Ccr-11-2535  1
2012 Heindl M, Hndel N, Ngeow J, Kionke J, Wittekind C, Kamprad M, Rensing-Ehl A, Ehl S, Reifenberger J, Loddenkemper C, Maul J, Hoffmeister A, Aretz S, Kiess W, Eng C, et al. Autoimmunity, intestinal lymphoid hyperplasia, and defects in mucosal B-cell homeostasis in patients with PTEN hamartoma tumor syndrome Gastroenterology. 142: 1093-1096.e6. PMID 22266152 DOI: 10.1053/J.Gastro.2012.01.011  1
2012 Hobert JA, Mester JL, Moline J, Eng C. Elevated plasma succinate in PTEN, SDHB, and SDHD mutation-positive individuals. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 14: 616-9. PMID 22261759 DOI: 10.1038/Gim.2011.63  1
2012 Tan MH, Mester JL, Ngeow J, Rybicki LA, Orloff MS, Eng C. Lifetime cancer risks in individuals with germline PTEN mutations. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 400-7. PMID 22252256 DOI: 10.1158/1078-0432.Ccr-11-2283  1
2012 Heald B, Edelman E, Eng C. Prospective comparison of family medical history with personal genome screening for risk assessment of common cancers. European Journal of Human Genetics : Ejhg. 20: 547-51. PMID 22215421 DOI: 10.1038/Ejhg.2011.224  1
2012 Bebek G, Bennett KL, Funchain P, Campbell R, Seth R, Scharpf J, Burkey B, Eng C. Microbiomic subprofiles and MDR1 promoter methylation in head and neck squamous cell carcinoma. Human Molecular Genetics. 21: 1557-65. PMID 22180460 DOI: 10.1093/Hmg/Ddr593  1
2012 Frazier TW, Youngstrom EA, Speer L, Embacher R, Law P, Constantino J, Findling RL, Hardan AY, Eng C. Validation of proposed DSM-5 criteria for autism spectrum disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 51: 28-40.e3. PMID 22176937 DOI: 10.1016/J.Jaac.2011.09.021  1
2012 Wang Y, He X, Ngeow J, Eng C. GATA2 negatively regulates PTEN by preventing nuclear translocation of androgen receptor and by androgen-independent suppression of PTEN transcription in breast cancer. Human Molecular Genetics. 21: 569-76. PMID 22021428 DOI: 10.1093/Hmg/Ddr491  1
2012 Ni Y, He X, Chen J, Moline J, Mester J, Orloff MS, Ringel MD, Eng C. Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53. Human Molecular Genetics. 21: 300-10. PMID 21979946 DOI: 10.1093/Hmg/Ddr459  1
2012 Tan MH, De S, Bebek G, Orloff MS, Wesolowski R, Downs-Kelly E, Budd GT, Stark GR, Eng C. Specific kinesin expression profiles associated with taxane resistance in basal-like breast cancer. Breast Cancer Research and Treatment. 131: 849-58. PMID 21479552 DOI: 10.1007/S10549-011-1500-8  1
2012 Ngeow J, Eng C. Thyroid cancer genetics: How close are we to personalizing clinical management? Personalized Medicine. 9: 355-358. DOI: 10.2217/pme.12.31  1
2012 Ngeow J, Eng C. PTEN mutations: Help spot thyroid cancer before it occurs Expert Review of Endocrinology and Metabolism. 7: 251-254. DOI: 10.1586/Eem.12.15  1
2012 Funchain P, Bebek G, Bennett KL, Burkey B, Eng C. Correlation of microbiomic profiles with disease status and MDR1 methylation in head and neck squamous cell carcinoma (HNSCC). Journal of Clinical Oncology. 30: 5573-5573. DOI: 10.1200/Jco.2012.30.15_Suppl.5573  1
2012 Mester J, Moore R, Eng C. PTEN germline mutations in patients first tested for other hereditary cancer syndromes: Would use of risk assessment tools have reduced health care costs? Journal of Clinical Oncology. 30: 1516-1516. DOI: 10.1200/Jco.2012.30.15_Suppl.1516  1
2012 Ngeow JYY, He X, Mester J, Radhakrishnan D, Lei J, Romigh T, Milas M, Eng C. Use of PTEN protein dosage to predict for underlying germ-line PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypes. Journal of Clinical Oncology. 30: 1508-1508. DOI: 10.1200/Jco.2012.30.15_Suppl.1508  1
2012 Wang Y, He X, Eng C. Abstract 4855: KLLN, which shares a bidirectional promoter with PTEN, is an AR-regulated tumor suppressor, and induces p53-dependent and -independent apoptosis in breast cancer Cancer Research. 72: 4855-4855. DOI: 10.1158/1538-7445.Am2012-4855  1
2012 Bebek G, Bennett KL, Funchain P, Campbell R, Seth R, Scharpf J, Burkey B, Eng C. Abstract 4087: Microbiomic subprofiles and MDR1 promoter methylation in head and neck squamous cell carcinoma Cancer Research. 72: 4087-4087. DOI: 10.1158/1538-7445.Am2012-4087  1
2012 Ni Y, Eng C. Abstract 1120: α-Tocopherol protects cells from lipid peroxidation and rescues tumorigenic phenotypes in CS/CSL patients with germline SDHx variants Cancer Research. 72: 1120-1120. DOI: 10.1158/1538-7445.Am2012-1120  1
2012 Tan MH, Mester J, Eng C. Lifetime Cancer Risks of PTEN Mutation Carriers—Response Clinical Cancer Research. 18: 4214-4214. DOI: 10.1158/1078-0432.Ccr-12-1128  1
2012 Mester J, Escobar P, Roma A, Eng C. Risk for endometrial carcinoma, ovarian tumors and other gynecologic diagnoses in a prospective series of women with cowden syndrome and germline PTEN mutation Gynecologic Oncology. 125. DOI: 10.1016/J.Ygyno.2011.12.075  1
2011 Levi Z, Baris HN, Kedar I, Niv Y, Geller A, Gal E, Gingold R, Morgenstern S, Baruch Y, Leach BH, Bronner MP, Eng C. Upper and Lower Gastrointestinal Findings in PTEN Mutation-Positive Cowden Syndrome Patients Participating in an Active Surveillance Program. Clinical and Translational Gastroenterology. 2: e5. PMID 23238744 DOI: 10.1038/Ctg.2011.4  1
2011 Moline J, Ngeow J, Rajiah P, Eng C. Evil lurks in the heart of man: cardiac paraganglioma presenting as recurrent dyspnoea and chronic cough Case Reports. 2011. PMID 22670000 DOI: 10.1136/Bcr.11.2011.5170  1
2011 Ngeow J, Mester J, Rybicki LA, Ni Y, Milas M, Eng C. Incidence and clinical characteristics of thyroid cancer in prospective series of individuals with Cowden and Cowden-like syndrome characterized by germline PTEN, SDH, or KLLN alterations. The Journal of Clinical Endocrinology and Metabolism. 96: E2063-71. PMID 21956414 DOI: 10.1210/Jc.2011-1616  1
2011 Sullivan M, Rybicki LA, Winter A, Hoffmann MM, Reiermann S, Linke H, Arbeiter K, Patzer L, Budde K, Hoppe B, Zeier M, Lhotta K, Bock A, Wiech T, Gaspert A, ... ... Eng C, et al. Age-related penetrance of hereditary atypical hemolytic uremic syndrome. Annals of Human Genetics. 75: 639-47. PMID 21906045 DOI: 10.1111/J.1469-1809.2011.00671.X  1
2011 Bebek G, Orloff M, Eng C. Microenvironmental genomic alterations reveal signaling networks for head and neck squamous cell carcinoma. Journal of Clinical Bioinformatics. 1: 21-21. PMID 21884569 DOI: 10.1186/2043-9113-1-21  1
2011 Gustafson SL, Pfeiffer G, Eng C. A large health system's approach to utilization of the genetic counselor CPT® 96040 code Genetics in Medicine. 13: 1011-1014. PMID 21857230 DOI: 10.1097/Gim.0B013E3182296344  0.01
2011 Sharp RR, Goldlust ME, Eng C. Addressing gaps in physician education using personal genomic testing. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 13: 750-1. PMID 21814069 DOI: 10.1097/Gim.0B013E318228821F  1
2011 Orloff M, Peterson C, He X, Ganapathi S, Heald B, Yang YR, Bebek G, Romigh T, Song JH, Wu W, David S, Cheng Y, Meltzer SJ, Eng C. Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma. Jama. 306: 410-9. PMID 21791690 DOI: 10.1001/Jama.2011.1029  1
2011 Limbach AL, Ni Y, Huang J, Eng C, Magi-Galluzzi C. Adenomatoid tumour of the adrenal gland in a patient with germline SDHD mutation: a case report and review of the literature. Pathology. 43: 495-8. PMID 21753715 DOI: 10.1097/Pat.0B013E3283486Bb9  0.01
2011 Neumann HP, Sullivan M, Winter A, Malinoc A, Hoffmann MM, Boedeker CC, Bertz H, Walz MK, Moeller LC, Schmid KW, Eng C. Germline mutations of the TMEM127 gene in patients with paraganglioma of head and neck and extraadrenal abdominal sites. The Journal of Clinical Endocrinology and Metabolism. 96: E1279-82. PMID 21613359 DOI: 10.1210/Jc.2011-0114  1
2011 Bennett KL, Campbell R, Ganapathi S, Zhou M, Rini B, Ganapathi R, Neumann HP, Eng C. Germline and somatic DNA methylation and epigenetic regulation of KILLIN in renal cell carcinoma. Genes, Chromosomes & Cancer. 50: 654-61. PMID 21584899 DOI: 10.1002/Gcc.20887  1
2011 Moline J, Eng C. Multiple endocrine neoplasia type 2: An overview Genetics in Medicine. 13: 755-764. PMID 21552134 DOI: 10.1097/Gim.0B013E318216Cc6D  1
2011 Wang Y, Romigh T, He X, Tan MH, Orloff MS, Silverman RH, Heston WD, Eng C. Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers Oncogene. 30: 4327-4338. PMID 21532617 DOI: 10.1038/Onc.2011.144  1
2011 Nagy R, Ganapathi S, Comeras I, Peterson C, Orloff M, Porter K, Eng C, Ringel MD, Kloos RT. Frequency of germline PTEN mutations in differentiated thyroid cancer. Thyroid : Official Journal of the American Thyroid Association. 21: 505-10. PMID 21417916 DOI: 10.1089/Thy.2010.0365  1
2011 Tan MH, Eng C. Testicular microlithiasis: Recent advances in understanding and management Nature Reviews Urology. 8: 153-163. PMID 21394177 DOI: 10.1038/Nrurol.2011.1  1
2011 Mester JL, Tilot AK, Rybicki LA, Frazier TW, Eng C. Analysis of prevalence and degree of macrocephaly in patients with germline PTEN mutations and of brain weight in Pten knock-in murine model. European Journal of Human Genetics : Ejhg. 19: 763-8. PMID 21343951 DOI: 10.1038/Ejhg.2011.20  1
2011 Kalady MF, Jarrar A, Leach B, LaGuardia L, O'Malley M, Eng C, Church JM. Defining phenotypes and cancer risk in hyperplastic polyposis syndrome. Diseases of the Colon & Rectum. 54: 164-170. PMID 21228663 DOI: 10.1007/Dcr.0B013E3181Fd4C15  1
2011 Eng C. Something old, something new Endocrine-Related Cancer. 18. PMID 21212159 DOI: 10.1677/ERC-10-0324  1
2011 Tan MH, Mester J, Peterson C, Yang Y, Chen JL, Rybicki LA, Milas K, Pederson HJ, Remzi B, Orloff MS, Eng C. A Clinical Scoring System for Selection of Patients for PTEN Mutation Testing Is Proposed on the Basis of a Prospective Study of 3042 Probands American Journal of Human Genetics. 88: 42-56. PMID 21194675 DOI: 10.1016/J.Ajhg.2010.11.013  1
2011 von Dücker L, Walz MK, Voss C, Arnold G, Eng C, Neumann HP. Laparoscopic organ-sparing resection of von Hippel-Lindau disease-associated pancreatic neuroendocrine tumors. World Journal of Surgery. 35: 563-7. PMID 21181474 DOI: 10.1007/S00268-010-0878-5  1
2011 Torres V, Triozzi P, Eng C, Tubbs R, Schoenfiled L, Crabb JW, Saunthararajah Y, Singh AD. Circulating tumor cells in uveal melanoma. Future Oncology. 7: 101-109. PMID 21174541 DOI: 10.2217/Fon.10.143  1
2011 He X, Wang Y, Zhu J, Orloff M, Eng C. Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling. Cancer Letters. 301: 168-76. PMID 21168265 DOI: 10.1016/J.Canlet.2010.11.012  1
2011 Frank-Raue K, Rybicki LA, Erlic Z, Schweizer H, Winter A, Milos I, Toledo SP, Toledo RA, Tavares MR, Alevizaki M, Mian C, Siggelkow H, Hüfner M, Wohllk N, Opocher G, ... ... Eng C, et al. Risk profiles and penetrance estimations in multiple endocrine neoplasia type 2A caused by germline RET mutations located in exon 10. Human Mutation. 32: 51-8. PMID 20979234 DOI: 10.1002/Humu.21385  1
2011 O’Malley M, LaGuardia L, Kalady M, Parambil J, Leach B, Eng C, Church J, Burke C. The prevalence of hereditary hemorrhagic telangiectasia in Juvenile Polyposis syndrome patients with SMAD4 mutations Hereditary Cancer in Clinical Practice. 9: 1-2. DOI: 10.1186/1897-4287-9-S1-O5  1
2011 Heald B, Eng C. Comparison of family health history to personal genomic screening for risk assessment of colon cancer Hereditary Cancer in Clinical Practice. 9: 1-1. DOI: 10.1186/1897-4287-9-S1-O2  1
2011 Ni Y, Eng C. Response to bayley: Functional study informs bioinformatic analysis American Journal of Human Genetics. 88: 676. DOI: 10.1016/J.Ajhg.2011.03.020  1
2010 Bennett KL, Mester J, Eng C. Germline epigenetic regulation of KILLIN in Cowden and Cowden-like syndrome. Jama. 304: 2724-31. PMID 21177507 DOI: 10.1001/Jama.2010.1877  1
2010 Eng C. Mendelian genetics of rare-and not so rare-cancers Annals of the New York Academy of Sciences. 1214: 70-82. PMID 20946573 DOI: 10.1111/J.1749-6632.2010.05789.X  1
2010 He X, Ni Y, Wang Y, Romigh T, Eng C. Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53. Human Molecular Genetics. 20: 80-9. PMID 20926450 DOI: 10.1093/Hmg/Ddq434  0.01
2010 Wang Y, Romigh T, He X, Orloff MS, Silverman RH, Heston WD, Eng C. Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines. Human Molecular Genetics. 19: 4319-29. PMID 20729295 DOI: 10.1093/Hmg/Ddq354  0.01
2010 Erlic Z, Ploeckinger U, Cascon A, Hoffmann MM, von Duecker L, Winter A, Kammel G, Bacher J, Sullivan M, Isermann B, Fischer L, Raffel A, Knoefel WT, Schott M, Baumann T, ... ... Eng C, et al. Systematic comparison of sporadic and syndromic pancreatic islet cell tumors. Endocrine-Related Cancer. 17: 875-83. PMID 20660572 DOI: 10.1677/Erc-10-0037  1
2010 Heald B, Mester J, Rybicki L, Orloff MS, Burke CA, Eng C. Frequent gastrointestinal polyps and colorectal adenocarcinomas in a prospective series of PTEN mutation carriers Gastroenterology. 139: 1927-1933. PMID 20600018 DOI: 10.1053/J.Gastro.2010.06.061  1
2010 Hansel DE, Platt E, Orloff M, Harwalker J, Sethu S, Hicks JL, De Marzo A, Steinle RE, Hsi ED, Theodorescu D, Ching CB, Eng C. Mammalian target of rapamycin (mTOR) regulates cellular proliferation and tumor growth in urothelial carcinoma. The American Journal of Pathology. 176: 3062-72. PMID 20395440 DOI: 10.2353/Ajpath.2010.090872  1
2010 Eng C, Sharp RR. Bioethical and clinical dilemmas of direct-to-consumer personal genomic testing: the problem of misattributed equivalence. Science Translational Medicine. 2: 17cm5. PMID 20371476 DOI: 10.1126/Scitranslmed.3000214  1
2010 Shiovitz S, Everett J, Huang SC, Orloff MS, Eng C, Gruber SB. Head circumference in the clinical detection of PTEN hamartoma tumor syndrome in a clinic population at high-risk of breast cancer. Breast Cancer Research and Treatment. 124: 459-65. PMID 20349131 DOI: 10.1007/S10549-010-0839-6  1
2010 Eng C. Common alleles of predisposition in endocrine neoplasia Current Opinion in Genetics and Development. 20: 251-256. PMID 20211557 DOI: 10.1016/J.Gde.2010.02.004  1
2010 Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen HZ, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Wang D, Sadee W, La Perle K, Stromberg P, ... ... Eng C, et al. Allele-specific tumor spectrum in pten knockin mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 5142-7. PMID 20194734 DOI: 10.1073/Pnas.0912524107  1
2010 Frazier TW, Youngstrom EA, Sinclair L, Kubu CS, Law P, Rezai A, Constantino JN, Eng C. Autism spectrum disorders as a qualitatively distinct category from typical behavior in a large, clinically ascertained sample. Assessment. 17: 308-20. PMID 20040725 DOI: 10.1177/1073191109356534  1
2010 Bennett KL, Lee W, Lamarre E, Zhang X, Seth R, Scharpf J, Hunt J, Eng C. HPV status-independent association of alcohol and tobacco exposure or prior radiation therapy with promoter methylation of FUSSEL18, EBF3, IRX1, and SEPT9, but not SLC5A8, in head and neck squamous cell carcinomas. Genes, Chromosomes & Cancer. 49: 319-26. PMID 20029986 DOI: 10.1002/Gcc.20742  1
2010 Waddell N, Arnold J, Cocciardi S, da Silva L, Marsh A, Riley J, Johnstone CN, Orloff M, Assie G, Eng C, Reid L, Keith P, Yan M, Fox S, Devilee P, et al. Subtypes of familial breast tumours revealed by expression and copy number profiling. Breast Cancer Research and Treatment. 123: 661-77. PMID 19960244 DOI: 10.1007/S10549-009-0653-1  1
2010 Erlic Z, Hoffmann MM, Sullivan M, Franke G, Peczkowska M, Harsch I, Schott M, Gabbert HE, Valimäki M, Preuss SF, Hasse-Lazar K, Waligorski D, Robledo M, Januszewicz A, Eng C, et al. Pathogenicity of DNA variants and double mutations in multiple endocrine neoplasia type 2 and von Hippel-Lindau syndrome. The Journal of Clinical Endocrinology and Metabolism. 95: 308-13. PMID 19906784 DOI: 10.1210/Jc.2009-1728  1
2010 Kirches E, Steiner J, Schneider T, Vorwerk CK, Scherlach C, Holtkamp N, Keilhoff G, Eng C, Mawrin C. Lhermitte-Duclos disease caused by a novel germline PTEN mutation R173P in a patient presenting with psychosis. Neuropathology and Applied Neurobiology. 36: 86-9. PMID 19719509 DOI: 10.1111/J.1365-2990.2009.01041.X  1
2010 Wesolowski R, Orloff M, Downs-Kelly E, Budd GT, Stark GR, De S, Tubbs RR, Crowe JP, Eng C. Effect of kinesins on taxane resistance. Journal of Clinical Oncology. 28: 10545-10545. DOI: 10.1200/Jco.2010.28.15_Suppl.10545  0.01
2010 Heald B, Mester J, Eng C. Gastrointestinal polyposis and PTEN mutations: an under-acknowledged diagnostic criterion Hereditary Cancer in Clinical Practice. 8: 1-1. DOI: 10.1186/1897-4287-8-S1-O3  1
2010 Eng C. Abstract CN04-04: Cancer predisposition: I say genetics, you say genomics, but are we there yet? Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-Cn04-04  0.01
2010 Bennett KL, Romigh T, Lee W, Lamarre E, Zhang X, Seth R, Scharpf J, Hunt J, Eng C. Abstract 4911: HPV-independent methylation of specific TGF-B pathway-relevant genes in head and neck squamous cell carcinomas associated with prior radiation therapy and exposure to alcohol and tobacco Cancer Research. 70: 4911-4911. DOI: 10.1158/1538-7445.Am10-4911  1
2010 Tuupanen S, Yan J, Turunen M, Gylfe A, Li L, Eng C, Culver D, Kalady M, Chapelle Adl, Askhtorab H, Smooth D, Sandler R, Keku T, Ellis N, Kupfer S, et al. Abstract 4731: Resequencing of the MYC-335 enhancer in the colorectal cancer associated 8q24 region Cancer Research. 70: 4731-4731. DOI: 10.1158/1538-7445.Am10-4731  1
2010 Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen H, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Perle KL, Stromberg P, Rosol TJ, Eng C, et al. Abstract 3260: Allele-specific tumor spectrum inPtenknockin mice Cancer Research. 70: 3260-3260. DOI: 10.1158/1538-7445.Am10-3260  1
2010 Orloff M, Elson P, Yang Y, Eng C, Hansel DE. Abstract 1810: PTEN association with mTOR pathway activation and outcomes in bladder cancer Cancer Research. 70: 1810-1810. DOI: 10.1158/1538-7445.Am10-1810  1
2010 Eng C. Robert J. Gorlin, DDS, MS (1923-2006): A geneticist for all seasons (Journal of Medical Genetics (2007) 44, (478-479) DOI: 10.1136/jmg.2006.048397) Journal of Medical Genetics. 47: 862. DOI: 10.1136/Jmg.2006.048397  1
2010 Tacon LJ, Soon PS, Gill AJ, Chou AS, Clarkson A, Botling J, Stalberg PL, Skogseid BM, Robinson BG, Sidhu SB, Clifton-Bligh RJ. The glucocorticoid receptor is overexpressed in malignant adrenocortical tumors Journal of Urology. 184: 1302. DOI: 10.1016/J.Juro.2010.06.076  0.01
2010 Edelman E, Eng C. PTEN Hamartoma Tumor Syndrome Management of Genetic Syndromes: Third Edition. 661-675. DOI: 10.1002/9780470893159.ch44  1
2009 Bennett KL, Romigh T, Eng C. Disruption of transforming growth factor-beta signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis. Cancer Research. 69: 9301-5. PMID 19934318 DOI: 10.1158/0008-5472.Can-09-3073  1
2009 Edelman E, Eng C. A practical guide to interpretation and clinical application of personal genomic screening. Bmj (Clinical Research Ed.). 339: b4253. PMID 19875427 DOI: 10.1136/Bmj.B4253  1
2009 Qian CN, Furge KA, Knol J, Huang D, Chen J, Dykema KJ, Kort EJ, Massie A, Khoo SK, Vanden Beldt K, Resau JH, Anema J, Kahnoski RJ, Morreau H, Camparo P, ... ... Eng C, et al. Activation of the PI3K/AKT pathway induces urothelial carcinoma of the renal pelvis: identification in human tumors and confirmation in animal models. Cancer Research. 69: 8256-64. PMID 19843858 DOI: 10.1158/0008-5472.Can-09-1689  1
2009 Erlic Z, Rybicki L, Peczkowska M, Golcher H, Kann PH, Brauckhoff M, Müssig K, Muresan M, Schäffler A, Reisch N, Schott M, Fassnacht M, Opocher G, Klose S, Fottner C, ... ... Eng C, et al. Clinical predictors and algorithm for the genetic diagnosis of pheochromocytoma patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6378-85. PMID 19825962 DOI: 10.1158/1078-0432.Ccr-09-1237  1
2009 Bennett KL, Romigh T, Eng C. AP-2alpha induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma. Plos One. 4: e6931. PMID 19742317 DOI: 10.1371/Journal.Pone.0006931  1
2009 Bekaii-Saab T, Markowitz J, Prescott N, Sadee W, Heerema N, Wei L, Dai Z, Papp A, Campbell A, Culler K, Balint C, O'Neil B, Lee RM, Zalupski M, Dancey J, ... ... Eng C, et al. A multi-institutional phase II study of the efficacy and tolerability of lapatinib in patients with advanced hepatocellular carcinomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5895-901. PMID 19737952 DOI: 10.1158/1078-0432.Ccr-09-0465  1
2009 Eng C, Leone G, Orloff MS, Ostrowski MC. Genomic alterations in tumor stroma. Cancer Research. 69: 6759-64. PMID 19706759 DOI: 10.1158/0008-5472.Can-09-0985  1
2009 Hobert JA, Eng C. PTEN hamartoma tumor syndrome: an overview. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 11: 687-94. PMID 19668082 DOI: 10.1097/Gim.0B013E3181Ac9Aea  1
2009 Neumann HPH, Eng C. The approach to the patient with paraganglioma Journal of Clinical Endocrinology and Metabolism. 94: 2677-2683. PMID 19657044 DOI: 10.1210/Jc.2009-0496  1
2009 Jacob AI, Romigh T, Waite KA, Eng C. Nuclear PTEN levels and G2 progression in melanoma cells. Melanoma Research. 19: 203-210. PMID 19478684 DOI: 10.1097/Cmr.0B013E32832Ccd6E  1
2009 Kloos RT, Eng C, Evans DB, Francis GL, Gagel RF, Gharib H, Moley JF, Pacini F, Ringel MD, Schlumberger M, Wells SA. Medullary thyroid cancer: management guidelines of the American Thyroid Association. Thyroid : Official Journal of the American Thyroid Association. 19: 565-612. PMID 19469690 DOI: 10.1089/Thy.2008.0403  1
2009 Lobo GP, Waite KA, Planchon SM, Romigh T, Nassif NT, Eng C. Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function. Human Molecular Genetics. 18: 2851-62. PMID 19457929 DOI: 10.1093/Hmg/Ddp220  1
2009 Zhao Y, Marotta M, Eichler EE, Eng C, Tanaka H. Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes. Plos Genetics. 5: e1000472. PMID 19424424 DOI: 10.1371/Journal.Pgen.1000472  1
2009 Neumann HP, Erlic Z, Boedeker CC, Rybicki LA, Robledo M, Hermsen M, Schiavi F, Falcioni M, Kwok P, Bauters C, Lampe K, Fischer M, Edelman E, Benn DE, Robinson BG, ... ... Eng C, et al. Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. Cancer Research. 69: 3650-6. PMID 19351833 DOI: 10.1158/0008-5472.Can-08-4057  1
2009 Boedeker CC, Erlic Z, Richard S, Kontny U, Gimenez-Roqueplo AP, Cascon A, Robledo M, de Campos JM, van Nederveen FH, de Krijger RR, Burnichon N, Gaal J, Walter MA, Reschke K, Wiech T, ... ... Eng C, et al. Head and neck paragangliomas in von Hippel-Lindau disease and multiple endocrine neoplasia type 2. The Journal of Clinical Endocrinology and Metabolism. 94: 1938-44. PMID 19336503 DOI: 10.1210/Jc.2009-0354  1
2009 Crouser ED, Culver DA, Knox KS, Julian MW, Shao G, Abraham S, Liyanarachchi S, Macre JE, Wewers MD, Gavrilin MA, Ross P, Abbas A, Eng C. Gene expression profiling identifies MMP-12 and ADAMDEC1 as potential pathogenic mediators of pulmonary sarcoidosis. American Journal of Respiratory and Critical Care Medicine. 179: 929-38. PMID 19218196 DOI: 10.1164/Rccm.200803-490Oc  1
2009 Lin MC, Lomo L, Baak JPA, Eng C, Ince TA, Crum CP, Mutter GL. Squamous morules are functionally inert elements of premalignant endometrial neoplasia Modern Pathology. 22: 167-174. PMID 19180120 DOI: 10.1038/Modpathol.2008.146  1
2009 Bennett KL, Romigh T, Arab K, Teresi RE, Tada Y, Eng C, Plass C. Activator protein 2 alpha (AP2alpha) suppresses 42 kDa C/CAAT enhancer binding protein alpha (p42(C/EBPalpha)) in head and neck squamous cell carcinoma. International Journal of Cancer. 124: 1285-92. PMID 19089912 DOI: 10.1002/Ijc.24087  1
2009 Orloff MS, Eng C. Genes Encoding Mitochondrial Enzyme Succinate Dehydrogenase Provide More Power for Breast Cancer Risk Assessment Breast Diseases: a Year Book Quarterly. 19: 298-302. DOI: 10.1016/S1043-321X(09)79232-X  1
2008 Eng C. Microenvironmental protection in diffuse large-B-cell lymphoma New England Journal of Medicine. 359: 2379-2381. PMID 19038884 DOI: 10.1056/Nejme0808409  1
2008 Eng C. Cancer: A ringleader identified Nature. 455: 883-884. PMID 18923503 DOI: 10.1038/455883A  1
2008 Peczkowska M, Erlic Z, Hoffmann MM, Furmanek M, Cwikla J, Kubaszek A, Prejbisz A, Szutkowski Z, Kawecki A, Chojnowski K, Lewczuk A, Litwin M, Szyfter W, Walter MA, Sullivan M, ... Eng C, et al. Impact of screening kindreds for SDHD p.Cys11X as a common mutation associated with paraganglioma syndrome type 1. The Journal of Clinical Endocrinology and Metabolism. 93: 4818-25. PMID 18826997 DOI: 10.1210/Jc.2008-1290  1
2008 Orloff MS, Eng C. Genetic and phenotypic heterogeneity in the PTEN hamartoma tumour syndrome Oncogene. 27: 5387-5397. PMID 18794875 DOI: 10.1038/Onc.2008.237  1
2008 Milos IN, Frank-Raue K, Wohllk N, Maia AL, Pusiol E, Patocs A, Robledo M, Biarnes J, Barontini M, Links TP, de Groot JW, Dvorakova S, Peczkowska M, Rybicki LA, Sullivan M, ... ... Eng C, et al. Age-related neoplastic risk profiles and penetrance estimations in multiple endocrine neoplasia type 2A caused by germ line RET Cys634Trp (TGC>TGG) mutation. Endocrine-Related Cancer. 15: 1035-41. PMID 18794325 DOI: 10.1677/Erc-08-0105  1
2008 Rigelsky CM, Jennings C, Lehtonen R, Minai OA, Eng C, Aldred MA. BMPR2 mutation in a patient with pulmonary arterial hypertension and suspected hereditary hemorrhagic telangiectasia American Journal of Medical Genetics Part A. 146: 2551-2556. PMID 18792970 DOI: 10.1002/Ajmg.A.32468  1
2008 Eng C. SDHB - A gene for all tumors? Journal of the National Cancer Institute. 100: 1193-1195. PMID 18728280 DOI: 10.1093/Jnci/Djn263  1
2008 Ni Y, Zbuk KM, Sadler T, Patocs A, Lobo G, Edelman E, Platzer P, Orloff MS, Waite KA, Eng C. Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes. American Journal of Human Genetics. 83: 261-8. PMID 18678321 DOI: 10.1016/J.Ajhg.2008.07.011  1
2008 Plon SE, Pirics ML, Nuchtern J, Hicks J, Russell H, Agrawal S, Zbuk K, Eng C, Hegde M, Chin EL. Multiple tumors in a child with germ-line mutations in TP53 and PTEN. The New England Journal of Medicine. 359: 537-9. PMID 18669439 DOI: 10.1056/Nejmc0800627  1
2008 Villalona-Calero MA, Otterson GA, Wientjes MG, Weber F, Bekaii-Saab T, Young D, Murgo AJ, Jensen R, Yeh TK, Wei Y, Zhang Y, Eng C, Grever M, Au JL. Noncytotoxic suramin as a chemosensitizer in patients with advanced non-small-cell lung cancer: a phase II study. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 19: 1903-9. PMID 18632723 DOI: 10.1093/Annonc/Mdn412  1
2008 Cho MY, Kim HS, Eng C, Kim DS, Kang SJ, Eom M, Yi SY, Bronner MP. First report of ovarian dysgerminoma in Cowden syndrome with germline PTEN mutation and PTEN-related 10q loss of tumor heterozygosity American Journal of Surgical Pathology. 32: 1258-1264. PMID 18594467 DOI: 10.1097/Pas.0B013E31816Be8B7  1
2008 Lobo GP, Waite KA, Planchon SM, Romigh T, Houghton JA, Eng C. ATP modulates PTEN subcellular localization in multiple cancer cell lines. Human Molecular Genetics. 17: 2877-85. PMID 18579579 DOI: 10.1093/Hmg/Ddn185  1
2008 Ahvenainen T, Lehtonen HJ, Lehtonen R, Vahteristo P, Aittomäki K, Baynam G, Dommering C, Eng C, Gruber SB, Grönberg H, Harvima R, Herva R, Hietala M, Kujala M, Kääriäinen H, et al. Mutation screening of fumarate hydratase by multiplex ligation-dependent probe amplification: detection of exonic deletion in a patient with leiomyomatosis and renal cell cancer Cancer Genetics and Cytogenetics. 183: 83-88. PMID 18503824 DOI: 10.1016/J.Cancergencyto.2008.01.010  1
2008 Pezzolesi MG, Platzer P, Waite KA, Eng C. Differential expression of PTEN-targeting microRNAs miR-19a and miR-21 in Cowden syndrome. American Journal of Human Genetics. 82: 1141-9. PMID 18460397 DOI: 10.1016/J.Ajhg.2008.04.005  1
2008 Sarquis MS, Silveira LG, Pimenta FJ, Dias EP, Teh BT, Friedman E, Gomez RS, Tavares GC, Eng C, De Marco L. Familial hyperparathyroidism: surgical outcome after 30 years of follow-up in three families with germline HRPT2 mutations. Surgery. 143: 630-40. PMID 18436011 DOI: 10.1016/j.surg.2007.12.012  1
2008 Alhopuro P, Phichith D, Tuupanen S, Sammalkorpi H, Nybondas M, Saharinen J, Robinson JP, Yang Z, Chen LQ, Orntoft T, Mecklin JP, Järvinen H, Eng C, Moeslein G, Shibata D, et al. Unregulated smooth-muscle myosin in human intestinal neoplasia. Proceedings of the National Academy of Sciences of the United States of America. 105: 5513-8. PMID 18391202 DOI: 10.1073/Pnas.0801213105  1
2008 Weber F, Eng C. Update on the molecular diagnosis of endocrine tumors: Toward -omics-based personalized healthcare? Journal of Clinical Endocrinology and Metabolism. 93: 1097-1104. PMID 18390809 DOI: 10.1210/Jc.2008-0212  1
2008 Assié G, LaFramboise T, Platzer P, Eng C. Frequency of germline genomic homozygosity associated with cancer cases. Jama. 299: 1437-1445. PMID 18364486 DOI: 10.1001/Jama.299.12.1437  1
2008 Assié G, LaFramboise T, Platzer P, Bertherat J, Stratakis CA, Eng C. SNP arrays in heterogeneous tissue: highly accurate collection of both germline and somatic genetic information from unpaired single tumor samples. American Journal of Human Genetics. 82: 903-915. PMID 18355774 DOI: 10.1016/J.Ajhg.2008.01.012  1
2008 Trimboli AJ, Fukino K, de Bruin A, Wei G, Shen L, Tanner SM, Creasap N, Rosol TJ, Robinson ML, Eng C, Ostrowski MC, Leone G. Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Research. 68: 937-45. PMID 18245497 DOI: 10.1158/0008-5472.Can-07-2148  1
2008 Triozzi PL, Eng C, Singh AD. Targeted therapy for uveal melanoma. Cancer Treatment Reviews. 34: 247-258. PMID 18226859 DOI: 10.1016/J.Ctrv.2007.12.002  1
2008 Planchon SM, Waite KA, Eng C. The nuclear affairs of PTEN. Journal of Cell Science. 121: 249-253. PMID 18216329 DOI: 10.1242/Jcs.022459  1
2008 Peczkowska M, Cascon A, Prejbisz A, Kubaszek A, Cwikła BJ, Furmanek M, Erlic Z, Eng C, Januszewicz A, Neumann HPH. Extra-adrenal and adrenal pheochromocytomas associated with a germline SDHC mutation. Nature Clinical Practice Endocrinology & Metabolism. 4: 111-115. PMID 18212813 DOI: 10.1038/Ncpendmet0726  1
2008 Teresi RE, Planchon SM, Waite KA, Eng C. Regulation of the PTEN promoter by statins and SREBP. Human Molecular Genetics. 17: 919-28. PMID 18065496 DOI: 10.1093/Hmg/Ddm364  1
2008 Ji J, Eng C, Hemminki K. Familial risk for soft tissue tumors : A nation-wide epidemiological study from Sweden Journal of Cancer Research and Clinical Oncology. 134: 617-624. PMID 17929055 DOI: 10.1007/S00432-007-0327-5  1
2008 Pasini B, McWhinney SR, Bei T, Matyakhina L, Stergiopoulos S, Muchow M, Boikos SA, Ferrando B, Pacak K, Assie G, Baudin E, Chompret A, Ellison JW, Briere JJ, Rustin P, ... ... Eng C, et al. Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD. European Journal of Human Genetics : Ejhg. 16: 79-88. PMID 17667967 DOI: 10.1038/Sj.Ejhg.5201904  1
2008 Svensson P, Molander M, Eng C, Anvret M, Nordenskjöld A. Low frequency of RET mutations in Hirschsprung disease in Sweden Clinical Genetics. 54: 39-44. PMID 9727738 DOI: 10.1111/J.1399-0004.1998.Tb03691.X  0.01
2008 Eng C. Interview: From high school dream to genomic medicine reality Personalized Medicine. 5: 569-573. DOI: 10.2217/17410541.5.6.569  1
2008 Markowitz J, Eng C, Sadee W, Heerema N, Li X, Campbell A, Culler K, O'Neil B, Lee R, Zalupski M, Dancey J, Grever M, Villalona-Calero M, Bekaii-Saab T. Abstract LB-306: A Phase II study of the efficacy and tolerability of Lapatinib in patients with advanced hepatocellular carcinomas. Cancer Research. 68. DOI: 10.1158/1538-7445.Am2008-Lb-306  1
2008 Chernausek SD, Eng CS. Pheochromocytoma and the Multiple Endocrine Neoplasia Syndromes Pediatric Endocrinology. 512-529. DOI: 10.1016/B978-141604090-3.50018-1  1
2008 Eng C, Assié G, LaFramboise TL. Germline Genomic Homozygosity and Cancer Risk—Reply Jama. 300: 169-170. DOI: 10.1001/Jama.300.2.170  1
2007 Patocs A, Zhang L, Xu Y, Weber F, Caldes T, Mutter GL, Platzer P, Eng C. Breast-cancer stromal cells with TP53 mutations and nodal metastases. The New England Journal of Medicine. 357: 2543-51. PMID 18094375 DOI: 10.1056/Nejmoa071825  1
2007 Zembowicz A, Knoepp SM, Bei T, Stergiopoulos S, Eng C, Mihm MC, Stratakis CA. Loss of expression of protein kinase A regulatory subunit 1α in pigmented epithelioid melanocytoma but not in melanoma or other melanocytic lesions The American Journal of Surgical Pathology. 31: 1764-1775. PMID 18059235 DOI: 10.1097/Pas.0B013E318057Faa7  1
2007 Cascon A, Landa I, Lopez-Jimenez E, Díez-Hernández A, Buchta M, Montero-Conde C, Leskelä S, Leandro-García LJ, Letón R, Rodríguez-Antona C, Eng C, Neumann HPH, Robledo M. Molecular characterisation of a common SDHB deletion in paraganglioma patients Journal of Medical Genetics. 45: 233-238. PMID 18057081 DOI: 10.1136/Jmg.2007.054965  1
2007 Heald B, Moran R, Milas M, Burke C, Eng C. Familial adenomatous polyposis in a patient with unexplained mental retardation. Nature Reviews Neurology. 3: 694-700. PMID 18046442 DOI: 10.1038/Ncpneuro0658  1
2007 Zbuk KM, Patocs A, Shealy A, Sylvester H, Miesfeldt S, Eng C. Germline mutations in PTEN and SDHC in a woman with epithelial thyroid cancer and carotid paraganglioma. Nature Clinical Practice. Oncology. 4: 608-12. PMID 17898811 DOI: 10.1038/Ncponc0935  1
2007 Neumann HPH, Vortmeyer A, Schmidt D, Werner M, Erlic Z, Cascon A, Bausch B, Januszewicz A, Eng C. Evidence of MEN-2 in the Original Description of Classic Pheochromocytoma The New England Journal of Medicine. 357: 1311-1315. PMID 17898100 DOI: 10.1056/Nejmoa071407  1
2007 Teresi RE, Zbuk KM, Pezzolesi MG, Waite KA, Eng C. Cowden syndrome-affected patients with PTEN promoter mutations demonstrate abnormal protein translation. American Journal of Human Genetics. 81: 756-67. PMID 17847000 DOI: 10.1086/521051  1
2007 Zbuk KM, Eng C. Hamartomatous polyposis syndromes Nature Clinical Practice Gastroenterology and Hepatology. 4: 492-502. PMID 17768394 DOI: 10.1038/Ncpgasthep0902  1
2007 Heald B, Hilden JM, Zbuk K, Norton A, Vyas P, Theil KS, Eng C. Severe TMD/AMKL with GATA1 mutation in a stillborn fetus with Down syndrome. Nature Clinical Practice. Oncology. 4: 433-8. PMID 17597708 DOI: 10.1038/Ncponc0876  1
2007 Ochs-Balcom HM, Falk G, Grady WM, Kinnard M, Willis J, Elston R, Eng C, Chak A. Consortium approach to identifying genes for Barrett's esophagus and esophageal adenocarcinoma. Translational Research : the Journal of Laboratory and Clinical Medicine. 150: 3-17. PMID 17585859 DOI: 10.1016/J.Trsl.2007.02.005  1
2007 Pinzone JJ, Eng C, Paik J, Brindle KA, Ringel MD, Katz JD. A novel PTEN mutation in Cowden syndrome is associated with a mixed degenerative-erosive arthritic process: potential molecular pathogenic mechanisms. American Journal of Medical Genetics. Part A. 143: 1522-7. PMID 17568419 DOI: 10.1002/Ajmg.A.31786  1
2007 Matyakhina L, Bei TA, McWhinney SR, Pasini B, Cameron S, Gunawan B, Stergiopoulos SG, Boikos S, Muchow M, Dutra A, Pak E, Campo E, Cid MC, Gomez F, Gaillard RC, ... ... Eng C, et al. Genetics of carney triad: recurrent losses at chromosome 1 but lack of germline mutations in genes associated with paragangliomas and gastrointestinal stromal tumors. The Journal of Clinical Endocrinology and Metabolism. 92: 2938-43. PMID 17535989 DOI: 10.1210/Jc.2007-0797  1
2007 Bennett KL, Hackanson B, Smith LT, Morrison CD, Lang JC, Schuller DE, Weber F, Eng C, Plass C. Tumor suppressor activity of CCAAT/enhancer binding protein alpha is epigenetically down-regulated in head and neck squamous cell carcinoma. Cancer Research. 67: 4657-64. PMID 17510391 DOI: 10.1158/0008-5472.Can-06-4793  1
2007 Fukino K, Shen L, Patocs A, Mutter GL, Eng C. Genomic instability within tumor stroma and clinicopathological characteristics of sporadic primary invasive breast carcinoma. Jama. 297: 2103-11. PMID 17507346 DOI: 10.1001/Jama.297.19.2103  1
2007 Minai OA, Rigelsky C, Eng C, Arroliga AC, Stoller JK. Long-term outcome in a patient with pulmonary hypertension and hereditary hemorrhagic telangiectasia. Chest. 131: 984-987. PMID 17426199 DOI: 10.1378/Chest.06-2275  1
2007 Bausch B, Borozdin W, Mautner VF, Hoffmann MM, Boehm D, Robledo M, Cascon A, Harenberg T, Schiavi F, Pawlu C, Peczkowska M, Letizia C, Calvieri S, Arnaldi G, Klingenberg-Noftz RD, ... ... Eng C, et al. Germline NF1 mutational spectra and loss-of-heterozygosity analyses in patients with pheochromocytoma and neurofibromatosis type 1. The Journal of Clinical Endocrinology and Metabolism. 92: 2784-92. PMID 17426081 DOI: 10.1210/Jc.2006-2833  1
2007 Alvarez-Breckenridge CA, Waite KA, Eng C. PTEN regulates phospholipase D and phospholipase C Human Molecular Genetics. 16: 1157-1163. PMID 17405772 DOI: 10.1093/Hmg/Ddm063  1
2007 Pezzolesi MG, Zbuk KM, Waite KA, Eng C. Comparative genomic and functional analyses reveal a novel cis-acting PTEN regulatory element as a highly conserved functional E-box motif deleted in Cowden syndrome. Human Molecular Genetics. 16: 1058-71. PMID 17341483 DOI: 10.1093/Hmg/Ddm053  1
2007 Wang Z, Yan P, Potter D, Eng C, Huang TH, Lin S. Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data. Bmc Bioinformatics. 8: 38. PMID 17270052 DOI: 10.1186/1471-2105-8-38  0.01
2007 Zbuk KM, Eng C. Predicting response to EGFR-tyrosine kinase inhibitors among diverse ancestries: Just 'way too polymorphic Cancer Biology and Therapy. 6: 112-115. PMID 17264670 DOI: 10.4161/Cbt.6.1.3787  1
2007 Kotsopoulos J, Lubinski J, Lynch HT, Klijn J, Ghadirian P, Neuhausen SL, Kim-Sing C, Foulkes WD, Moller P, Isaacs C, Domchek S, Randall S, Offit K, Tung N, Ainsworth P, ... ... Eng C, et al. Age at first birth and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment. 105: 221-8. PMID 17245541 DOI: 10.1007/S10549-006-9441-3  1
2007 Shen WH, Balajee AS, Wang J, Wu H, Eng C, Pandolfi PP, Yin Y. Essential role for nuclear PTEN in maintaining chromosomal integrity. Cell. 128: 157-70. PMID 17218262 DOI: 10.1016/J.Cell.2006.11.042  0.01
2007 Weber F, Xu Y, Zhang L, Patocs A, Shen L, Platzer P, Eng C. Microenvironmental genomic alterations and clinicopathological behavior in head and neck squamous cell carcinoma. Jama. 297: 187-95. PMID 17213402 DOI: 10.1001/Jama.297.2.187  1
2007 Yee LD, Williams N, Wen P, Young DC, Lester J, Johnson MV, Farrar WB, Walker MJ, Povoski SP, Suster S, Eng C. Pilot study of rosiglitazone therapy in women with breast cancer: effects of short-term therapy on tumor tissue and serum markers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 246-52. PMID 17200362 DOI: 10.1158/1078-0432.Ccr-06-1947  1
2007 Zbuk KM, Eng C. Cancer phenomics: RET and PTEN as illustrative models Nature Reviews Cancer. 7: 35-45. PMID 17167516 DOI: 10.1038/Nrc2037  1
2007 Finch A, Beiner M, Lubinski J, Lynch HT, Moller P, Rosen B, Murphy J, Ghadirian P, Friedman E, Foulkes WD, Kim-Sing C, Wagner T, Tung N, Couch F, Stoppa-Lyonnet D, ... ... Eng C, et al. Salpingo-oophorectomy and the Risk of Ovarian, Fallopian Tube, and Peritoneal Cancers in Women with a BRCA1 or BRCA2 Mutation Obstetrical & Gynecological Survey. 62: 29-31. DOI: 10.1097/01.Ogx.0000251480.69322.50  0.01
2006 Minaguchi T, Waite KA, Eng C. Nuclear Localization of PTEN Is Regulated by Ca2+ through a Tyrosil Phosphorylation–Independent Conformational Modification in Major Vault Protein Cancer Research. 66: 11677-11682. PMID 17178862 DOI: 10.1158/0008-5472.Can-06-2240  1
2006 Aldred MA, Eng C. SNP'ing at nasopharyngeal cancer susceptibility: For whom the bell tolls Cancer Biology and Therapy. 5: 1292-1293. PMID 17172806 DOI: 10.4161/Cbt.5.10.3487  1
2006 Bekaii-Saab T, Williams N, Plass C, Calero MV, Eng C. A novel mutation in the tyrosine kinase domain of ERBB2 in hepatocellular carcinoma. Bmc Cancer. 6: 278. PMID 17150109 DOI: 10.1186/1471-2407-6-278  0.01
2006 Yan PS, Venkataramu C, Ibrahim A, Liu JC, Shen RZ, Diaz NM, Centeno B, Weber F, Leu YW, Shapiro CL, Eng C, Yeatman TJ, Huang TH. Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6626-36. PMID 17121881 DOI: 10.1158/1078-0432.Ccr-06-0467  1
2006 Ruiz-Ferrer M, Fernández RM, Antiñolo G, López-Alonso M, Eng C, Borrego S. A complex additive model of inheritance for Hirschsprung disease is supported by both RET mutations and predisposing RET haplotypes. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 8: 704-10. PMID 17108762 DOI: 10.1097/01.Gim.0000245632.06064.F1  1
2006 Bausch B, Boedeker CC, Berlis A, Brink I, Cybulla M, Walz MK, Januszewicz A, Letizia C, Opocher G, Eng C, Neumann HPH. Genetic and clinical investigation of pheochromocytoma: a 22-year experience, from Freiburg, Germany to international effort. Annals of the New York Academy of Sciences. 1073: 122-137. PMID 17102079 DOI: 10.1196/Annals.1353.013  1
2006 Pezzolesi MG, Li Y, Zhou XP, Pilarski R, Shen L, Eng C. Mutation-positive and mutation-negative patients with Cowden and Bannayan-Riley-Ruvalcaba syndromes associated with distinct 10q haplotypes. American Journal of Human Genetics. 79: 923-34. PMID 17033968 DOI: 10.1086/508943  1
2006 Chak A, Faulx A, Eng C, Grady W, Kinnard M, Ochs-Balcom H, Falk G. Gastroesophageal reflux symptoms in patients with adenocarcinoma of the esophagus or cardia. Cancer. 107: 2160-6. PMID 17019737 DOI: 10.1002/Cncr.22245  0.01
2006 Chak A, Ochs-Balcom H, Falk G, Grady WM, Kinnard M, Willis JE, Elston R, Eng C. Familiality in Barrett's esophagus, adenocarcinoma of the esophagus, and adenocarcinoma of the gastroesophageal junction Cancer Epidemiology Biomarkers and Prevention. 15: 1668-1673. PMID 16985029 DOI: 10.1158/1055-9965.Epi-06-0293  1
2006 Jin M, Diaz PT, Bourgeois T, Eng C, Marsh CB, Wu HM. Two-dimensional gel proteome reference map of blood monocytes. Proteome Science. 4: 16. PMID 16948843 DOI: 10.1186/1477-5956-4-16  0.01
2006 Chung JH, Ostrowski MC, Romigh T, Minaguchi T, Waite KA, Eng C. The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation. Human Molecular Genetics. 15: 2553-9. PMID 16849370 DOI: 10.1093/Hmg/Ddl177  1
2006 Finch A, Beiner M, Lubinski J, Lynch HT, Moller P, Rosen B, Murphy J, Ghadirian P, Friedman E, Foulkes WD, Kim-Sing C, Wagner T, Tung N, Couch F, Stoppa-Lyonnet D, ... ... Eng C, et al. Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation. Jama. 296: 185-92. PMID 16835424 DOI: 10.1001/Jama.296.2.185  0.01
2006 Weber F, Teresi RE, Broelsch CE, Frilling A, Eng C. A limited set of human MicroRNA is deregulated in follicular thyroid carcinoma. The Journal of Clinical Endocrinology and Metabolism. 91: 3584-91. PMID 16822819 DOI: 10.1210/Jc.2006-0693  1
2006 Bausch B, Koschker AC, Fassnacht M, Stoevesandt J, Hoffmann MM, Eng C, Allolio B, Neumann HPH. Comprehensive Mutation Scanning of NF1 in Apparently Sporadic Cases of Pheochromocytoma The Journal of Clinical Endocrinology and Metabolism. 91: 3478-3481. PMID 16787982 DOI: 10.1210/Jc.2006-0780  1
2006 Tang Y, Eng C. p53 down-regulates phosphatase and tensin homologue deleted on chromosome 10 protein stability partially through caspase-mediated degradation in cells with proteasome dysfunction Cancer Research. 66: 6139-6148. PMID 16778187 DOI: 10.1158/0008-5472.Can-06-0772  1
2006 Sarquis MS, Agrawal S, Shen L, Pilarski R, Zhou XP, Eng C. Distinct expression profiles for PTEN transcript and its splice variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome. American Journal of Human Genetics. 79: 23-30. PMID 16773562 DOI: 10.1086/504392  0.01
2006 Tekin M, Hişmi BÖ, Fitoz S, Yalçinkaya F, Ekim M, Kansu A, Ertem M, Deda G, Tutar E, Arsan S, Zhou XP, Pilarski R, Eng C, Akar N. A germline PTEN mutation with manifestations of prenatal onset and verrucous epidermal nevus American Journal of Medical Genetics Part A. 140: 1472-1475. PMID 16752378 DOI: 10.1002/Ajmg.A.31273  1
2006 Kokko A, Laiho P, Lehtonen R, Korja S, Carvajal-Carmona LG, Järvinen H, Mecklin JP, Eng C, Schleutker J, Tomlinson IPM, Vahteristo P, Aaltonen LA. EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis Bmc Cancer. 6: 145-145. PMID 16740153 DOI: 10.1186/1471-2407-6-145  1
2006 Delnatte C, Sanlaville D, Mougenot JF, Vermeesch JR, Houdayer C, Blois MCD, Genevieve D, Goulet O, Fryns JP, Jaubert F, Vekemans M, Lyonnet S, Romana S, Eng C, Stoppa-Lyonnet D. Contiguous gene deletion within chromosome arm 10q is associated with juvenile polyposis of infancy, reflecting cooperation between the BMPR1A and PTEN tumor-suppressor genes. American Journal of Human Genetics. 78: 1066-1074. PMID 16685657 DOI: 10.1086/504301  1
2006 Weber F, Shen L, Fukino K, Patocs A, Mutter GL, Caldes T, Eng C. Total-genome analysis of BRCA1/2-related invasive carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation. American Journal of Human Genetics. 78: 961-72. PMID 16685647 DOI: 10.1086/504090  1
2006 Lim LC, Tan MH, Eng C, Teh BT, Rajasoorya RC. Thymic carcinoid in multiple endocrine neoplasia 1: genotype–phenotype correlation and prevention Journal of Internal Medicine. 259: 428-432. PMID 16594911 DOI: 10.1111/J.1365-2796.2006.01619.X  1
2006 Friedman E, Kotsopoulos J, Lubinski J, Lynch HT, Ghadirian P, Neuhausen SL, Isaacs C, Weber B, Foulkes WD, Moller P, Rosen B, Kim-Sing C, Gershoni-Baruch R, Ainsworth P, Daly M, ... ... Eng C, et al. Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers. Breast Cancer Research : Bcr. 8: R15. PMID 16563180 DOI: 10.1186/Bcr1387  1
2006 Agrawal S, Eng C. Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer Human Molecular Genetics. 15: 777-787. PMID 16436456 DOI: 10.1093/Hmg/Ddi492  1
2006 Teresi RE, Shaiu CW, Chen CS, Chatterjee VK, Waite KA, Eng C. Increased PTEN expression due to transcriptional activation of PPARgamma by Lovastatin and Rosiglitazone. International Journal of Cancer. 118: 2390-8. PMID 16425225 DOI: 10.1002/Ijc.21799  1
2006 Tang Y, Eng C. PTEN autoregulates its expression by stabilization of p53 in a phosphatase-independent manner Cancer Research. 66: 736-742. PMID 16424003 DOI: 10.1158/0008-5472.Can-05-1557  1
2006 Patterson AR, Leitch AM, Weatherall P, Zhou XP, Eng C, Tomlinson GE. Case 4. Fibrocystic breast disease in a 16-year-old female with PTEN hamartoma tumor syndrome Journal of Clinical Oncology. 24: 525-527. PMID 16421431 DOI: 10.1200/Jco.2004.01.0447  1
2006 Abdel-Rahman MH, Yang Y, Zhou XP, Craig EL, Davidorf FH, Eng C. High frequency of submicroscopic hemizygous deletion is a major mechanism of loss of expression of PTEN in uveal melanoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 288-95. PMID 16344319 DOI: 10.1200/Jco.2005.02.2418  1
2006 Perry CG, Young WF, McWhinney SR, Bei T, Stergiopoulos S, Knudson RA, Ketterling RP, Eng C, Stratakis CA, Carney JA. Functioning paraganglioma and gastrointestinal stromal tumor of the jejunum in three women: syndrome or coincidence. The American Journal of Surgical Pathology. 30: 42-9. PMID 16330941 DOI: 10.1097/01.Pas.0000178087.69394.9F  1
2006 Sarquis MS, Weber F, Shen L, Broelsch CE, Jhiang SM, Zedenius J, Frilling A, Eng C. High frequency of loss of heterozygosity in imprinted, compared with nonimprinted, genomic regions in follicular thyroid carcinomas and atypical adenomas. The Journal of Clinical Endocrinology and Metabolism. 91: 262-9. PMID 16249278 DOI: 10.1210/Jc.2005-1880  1
2006 Takahashi M, Yang XJ, McWhinney S, Sano N, Eng C, Kagawa S, Teh BT, Kanayama HO. cDNA microarray analysis assists in diagnosis of malignant intrarenal pheochromocytoma originally masquerading as a renal cell carcinoma. Journal of Medical Genetics. 42: e48. PMID 16061554 DOI: 10.1136/Jmg.2005.031708  0.01
2006 Nkondjock A, Ghadirian P, Kotsopoulos J, Lubinski J, Lynch H, Kim-Sing C, Horsman D, Rosen B, Isaacs C, Weber B, Foulkes W, Ainsworth P, Tung N, Eisen A, Friedman E, ... Eng C, et al. Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers. International Journal of Cancer. 118: 103-7. PMID 16032702 DOI: 10.1002/Ijc.21296  1
2006 Farag SS, Zhang S, Miller M, Buckner M, Kraut E, Chan K, Eng C, Byrd JC, Dancey JE, Grever MR. Phase II trial of temsirolimus (CCI-779) in patients with relapsed or refractory multiple myeloma (MM): Preliminary results Journal of Clinical Oncology. 24: 7616-7616. DOI: 10.1200/Jco.2006.24.18_Suppl.7616  1
2006 Sanlaville D, Delnatte C, Mougenot JF, Vermeesch JR, Houdayer C, Blois MCD, Genevieve D, Goulet O, Fryns JP, Jaubert F, Vekemans M, Lyonnet S, Romana S, Eng C, Stoppa-Lyonnet D. Reply to Salviati et al. American Journal of Human Genetics. 79: 596-597. DOI: 10.1086/507152  1
2006 Weber F, Radmacher M, Broelsch CE, Frilling A, Eng C. Over expression of human microRNAs contribute to follicular thyroid carcinogenesis (FTC) Journal of the American College of Surgeons. 203. DOI: 10.1016/J.Jamcollsurg.2006.05.122  1
2005 Bekaii-Saab TS, Sawada T, Williams N, Frankel W, Plass C, Villalona-Calero M, Eng C. Intragenic EGFR and EGFR2 mutations in hepatobiliary tumors and potential role in predicting response to agents that target EGFR. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 4037. PMID 27944143 DOI: 10.1200/Jco.2005.23.16_Suppl.4037  1
2005 Eng C, Weber F. Gene-expression profiling in differentiated thyroid cancer - A viable strategy for the practice of genomic medicine? Future Oncology. 1: 497-510. PMID 16556026 DOI: 10.2217/14796694.1.4.497  1
2005 Bermejo JL, Eng C, Hemminki K. Cancer characteristics in Swedish families fulfilling criteria for hereditary nonpolyposis colorectal cancer. Gastroenterology. 129: 1889-1899. PMID 16344057 DOI: 10.1053/J.Gastro.2005.09.012  1
2005 Eng C. Serendipity, fate, science and leadership Cancer Biology &Amp; Therapy.. 4: 1422-1425. PMID 16322685 DOI: 10.4161/Cbt.4.12.2336  1
2005 Sweet K, Willis J, Zhou XP, Gallione C, Sawada T, Alhopuro P, Khoo SK, Patocs A, Martin C, Bridgeman S, Heinz J, Pilarski R, Lehtonen R, Prior TW, Frebourg T, ... ... Eng C, et al. Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis. Jama. 294: 2465-73. PMID 16287957 DOI: 10.1001/Jama.294.19.2465  1
2005 Weber F, Eng C. Editorial: Germline variants within RET: Clinical utility or scientific playtoy? Journal of Clinical Endocrinology and Metabolism. 90: 6334-6336. PMID 16275981 DOI: 10.1210/Jc.2005-2030  1
2005 Schiavi F, Boedeker CC, Bausch B, Peçzkowska M, Gomez CF, Strassburg T, Pawlu C, Buchta M, Salzmann M, Hoffmann MM, Berlis A, Brink I, Cybulla M, Muresan M, Walter MA, ... ... Eng C, et al. Predictors and prevalence of paraganglioma syndrome associated with mutations of the SDHC gene. Jama. 294: 2057-63. PMID 16249420 DOI: 10.1001/Jama.294.16.2057  1
2005 Marsee DK, Vadysirisack DD, Morrison CD, Prasad ML, Eng C, Duh QY, Rauen KA, Kloos RT, Jhiang SM. Variable expression of coxsackie-adenovirus receptor in thyroid tumors: implications for adenoviral gene therapy. Thyroid : Official Journal of the American Thyroid Association. 15: 977-87. PMID 16187905 DOI: 10.1089/Thy.2005.15.977  1
2005 Chung JH, Eng C. Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis Cancer Research. 65: 8096-8100. PMID 16166282 DOI: 10.1158/0008-5472.Can-05-1888  1
2005 Eng C. High frequency of large gene deletions and rearrangements in Lynch syndrome-back to the future? Gastroenterology. 129: 1124-1126. PMID 16143150 DOI: 10.1053/J.Gastro.2005.07.043  1
2005 Weber F, Fukino K, Villalona-Calero M, Eng C. Limitations of Single-Strand Conformation Polymorphism Analysis As a High-Throughput Method for the Detection of EGFR Mutations in the Clinical Setting Journal of Clinical Oncology. 23: 5847-5848. PMID 16110042 DOI: 10.1200/Jco.2005.01.5222  1
2005 Dourisboure RJ, Belli S, Domenichini E, Podestá EJ, Eng C, Solano AR. Penetrance and Clinical Manifestations of Non-Hotspot Germline RET Mutation, C630R, in a Family with Medullary Thyroid Carcinoma Thyroid. 15: 668-671. PMID 16053382 DOI: 10.1089/Thy.2005.15.668  0.01
2005 Hemminki K, Eng C, Chen B. Familial Risks for Nonmedullary Thyroid Cancer The Journal of Clinical Endocrinology and Metabolism. 90: 5747-5753. PMID 16030170 DOI: 10.1210/Jc.2005-0935  1
2005 Agrawal S, Pilarski R, Eng C. Different splicing defects lead to differential effects downstream of the lipid and protein phosphatase activities of PTEN Human Molecular Genetics. 14: 2459-2468. PMID 16014636 DOI: 10.1093/Hmg/Ddi246  1
2005 Chung JH, Ginn-Pease ME, Eng C. Phosphatase and Tensin Homologue Deleted on Chromosome 10 (PTEN) Has Nuclear Localization Signal–Like Sequences for Nuclear Import Mediated by Major Vault Protein Cancer Research. 65: 4108-4116. PMID 15899801 DOI: 10.1158/0008-5472.Can-05-0124  1
2005 Weber F, Fukino K, Sawada T, Williams N, Sweet K, Brena RM, Plass C, Caldes T, Mutter GL, Villalona-Calero MA, Eng C. Variability in organ-specific EGFR mutational spectra in tumour epithelium and stroma may be the biological basis for differential responses to tyrosine kinase inhibitors British Journal of Cancer. 92: 1922-1926. PMID 15841079 DOI: 10.1038/Sj.Bjc.6602557  1
2005 Waite KA, Sinden MR, Eng C. Phytoestrogen exposure elevates PTEN levels Human Molecular Genetics. 14: 1457-1463. PMID 15829497 DOI: 10.1093/Hmg/Ddi155  1
2005 Fernandez RM, Boru G, Peciña A, Jones K, López-Alonso M, Antiñolo G, Borrego S, Eng C. Ancestral RET haplotype associated with Hirschsprung's disease shows linkage disequilibrium breakpoint at -1249. Journal of Medical Genetics. 42: 322-7. PMID 15805159 DOI: 10.1136/Jmg.2004.023960  1
2005 Weber F, Shen L, Aldred MA, Morrison CD, Frilling A, Saji M, Schuppert F, Broelsch CE, Ringel MD, Eng C. Genetic classification of benign and malignant thyroid follicular neoplasia based on a three-gene combination. The Journal of Clinical Endocrinology and Metabolism. 90: 2512-21. PMID 15713710 DOI: 10.1210/Jc.2004-2028  1
2005 Eng C. Molecular Basis of Thyroid Cancer Thyroid. 15: 1109-1109. DOI: 10.1089/Thy.2005.15.1109  0.01
2005 Faulx A, Grady W, Eng C, Kinnard M, Falk G, Chak A. The Prevalence of GERD in Patients with Esophageal Adenocarcinoma (EAC) and Esophagogastric Junctional Adenocarcinoma (EGJAC) Gastrointestinal Endoscopy. 61. DOI: 10.1016/S0016-5107(05)00775-3  1
2005 Neumann HPH, Opocher G, Januszewicz A, Eng C. Pheochromocytoma – where are we? Where should we go? A medical and scientific odyssey Familial Cancer. 4: 1-1. DOI: 10.1007/S10689-004-0620-2  1
2004 Rhoades CA, Kraut E, Schuller D, Zhang Y, Chan K, Lang K, Eng C, Grever M. Phase I and II study of OSI-774 and docetaxel in squamous cell carcinoma of the head and neck (SCCHN). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 5541. PMID 28013997 DOI: 10.1200/Jco.2004.22.14_Suppl.5541  1
2004 Weber F, Aldred MA, Morrison CD, Plass C, Frilling A, Broelsch CE, Waite KA, Eng C. Silencing of the maternally imprinted tumor suppressor ARHI contributes to follicular thyroid carcinogenesis. The Journal of Clinical Endocrinology and Metabolism. 90: 1149-55. PMID 15546898 DOI: 10.1210/Jc.2004-1447  0.01
2004 McWhinney SR, Pilarski RT, Forrester SR, Schneider MC, Sarquis MM, Dias EP, Eng C. Large germline deletions of mitochondrial complex II subunits SDHB and SDHD in hereditary paraganglioma. The Journal of Clinical Endocrinology and Metabolism. 89: 5694-9. PMID 15531530 DOI: 10.1210/Jc.2004-0769  1
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