Julien Sage - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Oncology, Molecular Biology

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Rudin CM, Poirier JT, Byers LA, Dive C, Dowlati A, George J, Heymach JV, Johnson JE, Lehman JM, MacPherson D, Massion PP, Minna JD, Oliver TG, Quaranta V, Sage J, et al. Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data. Nature Reviews. Cancer. PMID 31175338 DOI: 10.1038/s41568-019-0164-2  0.36
2019 Rudin CM, Poirier JT, Byers LA, Dive C, Dowlati A, George J, Heymach JV, Johnson JE, Lehman JM, MacPherson D, Massion PP, Minna JD, Oliver TG, Quaranta V, Sage J, et al. Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data. Nature Reviews. Cancer. PMID 30926931 DOI: 10.1038/s41568-019-0133-9  0.36
2018 Kareta MS, Sage J. Cancer origins-genetics rules the day. Science (New York, N.Y.). 362: 30-31. PMID 30287650 DOI: 10.1126/science.aav1044  0.36
2017 Mello SS, Sinow C, Raj N, Mazur PK, Bieging-Rolett K, Broz DK, Imam JFC, Vogel H, Wood LD, Sage J, Hirose T, Nakagawa S, Rinn J, Attardi LD. Neat1 is a p53-inducible lincRNA essential for transformation suppression. Genes & Development. PMID 28698299 DOI: 10.1101/gad.284661.116  0.8
2016 Hubner EK, Lechler C, Kohnke-Ertel B, Zmoos AF, Sage J, Schmid RM, Ehmer U. An in vivo transfection system for inducible gene expression and gene silencing in murine hepatocytes. The Journal of Gene Medicine. PMID 28009940 DOI: 10.1002/jgm.2940  0.36
2016 Denny SK, Yang D, Chuang CH, Brady JJ, Lim JS, Grüner BM, Chiou SH, Schep AN, Baral J, Hamard C, Antoine M, Wislez M, Kong CS, Connolly AJ, Park KS, ... Sage J, et al. Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility. Cell. PMID 27374332 DOI: 10.1016/j.cell.2016.05.052  0.96
2016 Jahchan NS, Lim JS, Bola B, Morris K, Seitz G, Tran KQ, Xu L, Trapani F, Morrow CJ, Cristea S, Coles GL, Yang D, Vaka D, Kareta MS, George J, ... ... Sage J, et al. Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer. Cell Reports. PMID 27373157 DOI: 10.1016/j.celrep.2016.06.021  0.96
2016 Weiskopf K, Jahchan NS, Schnorr PJ, Cristea S, Ring AM, Maute RL, Volkmer AK, Volkmer JP, Liu J, Lim JS, Yang D, Seitz G, Nguyen T, Wu D, Jude K, ... ... Sage J, et al. CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. The Journal of Clinical Investigation. PMID 27294525 DOI: 10.1172/JCI81603  0.96
2016 Krampitz GW, George BM, Willingham SB, Volkmer JP, Weiskopf K, Jahchan N, Newman AM, Sahoo D, Zemek AJ, Yanovsky RL, Nguyen JK, Schnorr PJ, Mazur PK, Sage J, Longacre TA, et al. Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035983 DOI: 10.1073/pnas.1600007113  0.96
2016 Reynoird N, Mazur PK, Stellfeld T, Flores NM, Lofgren SM, Carlson SM, Brambilla E, Hainaut P, Kaznowska EB, Arrowsmith CH, Khatri P, Stresemann C, Gozani O, Sage J. Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer. Genes & Development. PMID 26988419 DOI: 10.1101/gad.275529.115  0.96
2016 Bunn PA, Minna J, Augustyn A, Gazdar A, Ouadah Y, Krasnow MA, Berns A, Brambilla E, Rekhtman N, Massion PP, Niederst M, Peifer M, Yokota J, Govindan R, Poirier J, ... ... Sage J, et al. Small Cell Lung Cancer: Can recent advances in biology and molecular biology be translated into improved outcomes? Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 26829312 DOI: 10.1016/j.jtho.2016.01.012  0.96
2015 Kareta MS, Sage J, Wernig M. Crosstalk between stem cell and cell cycle machineries. Current Opinion in Cell Biology. 37: 68-74. PMID 26520682 DOI: 10.1016/j.ceb.2015.10.001  0.96
2015 Mazur PK, Herner A, Mello SS, Wirth M, Hausmann S, Sánchez-Rivera FJ, Lofgren SM, Kuschma T, Hahn SA, Vangala D, Trajkovic-Arsic M, Gupta A, Heid I, Noël PB, Braren R, ... ... Sage J, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nature Medicine. PMID 26390243 DOI: 10.1038/nm.3952  0.96
2015 Gazdar AF, Savage TK, Johnson JE, Berns A, Sage J, Linnoila RI, MacPherson D, McFadden DG, Farago A, Jacks T, Travis WD, Brambilla E. The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 553-64. PMID 25675280 DOI: 10.1097/JTO.0000000000000459  0.96
2015 Kareta MS, Gorges LL, Hafeez S, Benayoun BA, Marro S, Zmoos AF, Cecchini MJ, Spacek D, Batista LF, O'Brien M, Ng YH, Ang CE, Vaka D, Artandi SE, Dick FA, ... ... Sage J, et al. Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis. Cell Stem Cell. 16: 39-50. PMID 25467916 DOI: 10.1016/j.stem.2014.10.019  0.96
2015 Xu L, Hazard FK, Zmoos AF, Jahchan N, Chaib H, Garfin PM, Rangaswami A, Snyder MP, Sage J. Genomic analysis of fibrolamellar hepatocellular carcinoma. Human Molecular Genetics. 24: 50-63. PMID 25122662 DOI: 10.1093/hmg/ddu418  0.96
2014 Bremner R, Sage J. Cancer: The origin of human retinoblastoma. Nature. 514: 312-3. PMID 25252972 DOI: 10.1038/nature13748  0.96
2014 Santos M, Martínez-Fernández M, Dueñas M, García-Escudero R, Alfaya B, Villacampa F, Saiz-Ladera C, Costa C, Oteo M, Duarte J, Martínez V, Gómez-Rodriguez MJ, Martín ML, Fernández M, Viatour P, ... ... Sage J, et al. In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer. Cancer Research. 74: 6565-77. PMID 25252918 DOI: 10.1158/0008-5472.CAN-14-1218  0.96
2014 Ehmer U, Zmoos AF, Auerbach RK, Vaka D, Butte AJ, Kay MA, Sage J. Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo. Cell Reports. 8: 371-81. PMID 25017070 DOI: 10.1016/j.celrep.2014.06.025  0.96
2014 Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, ... Sage J, et al. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature. 510: 283-7. PMID 24847881 DOI: 10.1038/nature13320  0.96
2014 Ntziachristos P, Lim JS, Sage J, Aifantis I. From fly wings to targeted cancer therapies: a centennial for notch signaling. Cancer Cell. 25: 318-34. PMID 24651013 DOI: 10.1016/j.ccr.2014.02.018  0.96
2013 Rubin SM, Sage J. Defining a new vision for the retinoblastoma gene: report from the 3rd International Rb Meeting. Cell Division. 8: 13. PMID 24257515 DOI: 10.1186/1747-1028-8-13  0.96
2013 Jahchan NS, Dudley JT, Mazur PK, Flores N, Yang D, Palmerton A, Zmoos AF, Vaka D, Tran KQ, Zhou M, Krasinska K, Riess JW, Neal JW, Khatri P, Park KS, ... ... Sage J, et al. A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Cancer Discovery. 3: 1364-77. PMID 24078773 DOI: 10.1158/2159-8290.CD-13-0183  0.96
2013 Garfin PM, Min D, Bryson JL, Serwold T, Edris B, Blackburn CC, Richie ER, Weinberg KI, Manley NR, Sage J, Viatour P. Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. The Journal of Experimental Medicine. 210: 1087-97. PMID 23669396 DOI: 10.1084/jem.20121716  0.96
2013 Attardi LD, Sage J. RB goes mitochondrial Genes and Development. 27: 975-979. PMID 23651852 DOI: 10.1101/gad.219451.113  0.96
2013 Jameson KL, Mazur PK, Zehnder AM, Zhang J, Zarnegar B, Sage J, Khavari PA. IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors. Nature Medicine. 19: 626-30. PMID 23603816 DOI: 10.1038/nm.3165  0.96
2012 Conklin JF, Baker J, Sage J. The RB family is required for the self-renewal and survival of human embryonic stem cells. Nature Communications. 3: 1244. PMID 23212373 DOI: 10.1038/ncomms2254  0.96
2012 Shin MK, Sage J, Lambert PF. Inactivating all three rb family pocket proteins is insufficient to initiate cervical cancer. Cancer Research. 72: 5418-27. PMID 22942253 DOI: 10.1158/0008-5472.CAN-12-2083  0.96
2012 Sage J. The retinoblastoma tumor suppressor and stem cell biology. Genes & Development. 26: 1409-20. PMID 22751497 DOI: 10.1101/gad.193730.112  0.96
2012 Van Aller GS, Reynoird N, Barbash O, Huddleston M, Liu S, Zmoos AF, McDevitt P, Sinnamon R, Le B, Mas G, Annan R, Sage J, Garcia BA, Tummino PJ, Gozani O, et al. Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation. Epigenetics. 7: 340-3. PMID 22419068 DOI: 10.4161/epi.19506  0.96
2012 Sage J, Cleary ML. Genomics: The path to retinoblastoma. Nature. 481: 269-70. PMID 22258599 DOI: 10.1038/481269a  0.96
2011 Chen H, Gu X, Liu Y, Wang J, Wirt SE, Bottino R, Schorle H, Sage J, Kim SK. PDGF signalling controls age-dependent proliferation in pancreatic β-cells. Nature. 478: 349-55. PMID 21993628 DOI: 10.1038/nature10502  0.96
2011 Park KS, Martelotto LG, Peifer M, Sos ML, Karnezis AN, Mahjoub MR, Bernard K, Conklin JF, Szczepny A, Yuan J, Guo R, Ospina B, Falzon J, Bennett S, Brown TJ, ... ... Sage J, et al. A crucial requirement for Hedgehog signaling in small cell lung cancer. Nature Medicine. 17: 1504-8. PMID 21983857 DOI: 10.1038/nm.2473  0.96
2011 Taguchi A, Politi K, Pitteri SJ, Lockwood WW, Faça VM, Kelly-Spratt K, Wong CH, Zhang Q, Chin A, Park KS, Goodman G, Gazdar AF, Sage J, Dinulescu DM, Kucherlapati R, et al. Lung cancer signatures in plasma based on proteome profiling of mouse tumor models. Cancer Cell. 20: 289-99. PMID 21907921 DOI: 10.1016/j.ccr.2011.08.007  0.96
2011 Viatour P, Sage J. Newly identified aspects of tumor suppression by RB. Disease Models & Mechanisms. 4: 581-5. PMID 21878458 DOI: 10.1242/dmm.008060  0.96
2011 Viatour P, Ehmer U, Saddic LA, Dorrell C, Andersen JB, Lin C, Zmoos AF, Mazur PK, Schaffer BE, Ostermeier A, Vogel H, Sylvester KG, Thorgeirsson SS, Grompe M, Sage J. Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway. The Journal of Experimental Medicine. 208: 1963-76. PMID 21875955 DOI: 10.1084/jem.20110198  0.96
2011 Sage J, Ventura A. miR than meets the eye. Genes & Development. 25: 1663-7. PMID 21852531 DOI: 10.1101/gad.17454011  0.96
2011 Sirota M, Dudley JT, Kim J, Chiang AP, Morgan AA, Sweet-Cordero A, Sage J, Butte AJ. Discovery and preclinical validation of drug indications using compendia of public gene expression data. Science Translational Medicine. 3: 96ra77. PMID 21849665 DOI: 10.1126/scitranslmed.3001318  0.96
2011 McEvoy J, Flores-Otero J, Zhang J, Nemeth K, Brennan R, Bradley C, Krafcik F, Rodriguez-Galindo C, Wilson M, Xiong S, Lozano G, Sage J, Fu L, Louhibi L, Trimarchi J, et al. Coexpression of normally incompatible developmental pathways in retinoblastoma genesis. Cancer Cell. 20: 260-75. PMID 21840489 DOI: 10.1016/j.ccr.2011.07.005  0.96
2011 Park KS, Liang MC, Raiser DM, Zamponi R, Roach RR, Curtis SJ, Walton Z, Schaffer BE, Roake CM, Zmoos AF, Kriegel C, Wong KK, Sage J, Kim CF. Characterization of the cell of origin for small cell lung cancer. Cell Cycle (Georgetown, Tex.). 10: 2806-15. PMID 21822053 DOI: 10.4161/cc.10.16.17012  0.96
2011 Redwood AB, Perkins SM, Vanderwaal RP, Feng Z, Biehl KJ, Gonzalez-Suarez I, Morgado-Palacin L, Shi W, Sage J, Roti-Roti JL, Stewart CL, Zhang J, Gonzalo S. A dual role for A-type lamins in DNA double-strand break repair. Cell Cycle (Georgetown, Tex.). 10: 2549-60. PMID 21701264 DOI: 10.4161/cc.10.15.16531  0.96
2011 Manley NR, Richie ER, Blackburn CC, Condie BG, Sage J. Structure and function of the thymic microenvironment. Frontiers in Bioscience (Landmark Edition). 16: 2461-77. PMID 21622189 DOI: 10.2741/3866  0.96
2011 Saddic LA, Wirt S, Vogel H, Felsher DW, Sage J. Functional interactions between retinoblastoma and c-MYC in a mouse model of hepatocellular carcinoma. Plos One. 6: e19758. PMID 21573126 DOI: 10.1371/journal.pone.0019758  0.96
2011 Arnold CP, Tan R, Zhou B, Yue SB, Schaffert S, Biggs JR, Doyonnas R, Lo MC, Perry JM, Renault VM, Sacco A, Somervaille T, Viatour P, Brunet A, Cleary ML, ... ... Sage J, et al. MicroRNA programs in normal and aberrant stem and progenitor cells. Genome Research. 21: 798-810. PMID 21451113 DOI: 10.1101/gr.111385.110  0.96
2011 Bourgo RJ, Ehmer U, Sage J, Knudsen ES. RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo. Molecular Biology of the Cell. 22: 931-9. PMID 21289097 DOI: 10.1091/mbc.E10-11-0895  0.96
2010 Wirt SE, Adler AS, Gebala V, Weimann JM, Schaffer BE, Saddic LA, Viatour P, Vogel H, Chang HY, Meissner A, Sage J. G1 arrest and differentiation can occur independently of Rb family function. The Journal of Cell Biology. 191: 809-25. PMID 21059851 DOI: 10.1083/jcb.201003048  0.96
2010 Saddic LA, West LE, Aslanian A, Yates JR, Rubin SM, Gozani O, Sage J. Methylation of the retinoblastoma tumor suppressor by SMYD2. The Journal of Biological Chemistry. 285: 37733-40. PMID 20870719 DOI: 10.1074/jbc.M110.137612  0.96
2010 Pajcini KV, Corbel SY, Sage J, Pomerantz JH, Blau HM. Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle. Cell Stem Cell. 7: 198-213. PMID 20682446 DOI: 10.1016/j.stem.2010.05.022  0.96
2010 Burkhart DL, Wirt SE, Zmoos AF, Kareta MS, Sage J. Tandem E2F binding sites in the promoter of the p107 cell cycle regulator control p107 expression and its cellular functions. Plos Genetics. 6: e1001003. PMID 20585628 DOI: 10.1371/journal.pgen.1001003  0.96
2010 Sage J, Straight AF. RB's original CIN? Genes & Development. 24: 1329-33. PMID 20551167 DOI: 10.1101/gad.1948010  0.96
2010 Schaffer BE, Park KS, Yiu G, Conklin JF, Lin C, Burkhart DL, Karnezis AN, Sweet-Cordero EA, Sage J. Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma. Cancer Research. 70: 3877-83. PMID 20406986 DOI: 10.1158/0008-5472.CAN-09-4228  0.96
2010 Burkhart DL, Sage J. Complex transcriptional regulatory networks around the retinoblastoma tumor suppressor gene Cell Cycle. 9: 1663-1664. PMID 20404509 DOI: 10.4161/cc.9.9.11593  0.96
2010 Wirt SE, Sage J. p107 in the public eye: an Rb understudy and more. Cell Division. 5: 9. PMID 20359370 DOI: 10.1186/1747-1028-5-9  0.36
2010 Burkhart DL, Ngai LK, Roake CM, Viatour P, Thangavel C, Ho VM, Knudsen ES, Sage J. Regulation of RB transcription in vivo by RB family members. Molecular and Cellular Biology. 30: 1729-45. PMID 20100864 DOI: 10.1128/MCB.00952-09  0.96
2009 Conklin JF, Sage J. Keeping an eye on retinoblastoma control of human embryonic stem cells Journal of Cellular Biochemistry. 108: 1023-1030. PMID 19760644 DOI: 10.1002/jcb.22342  0.96
2009 Gonzalez-Suarez I, Redwood AB, Perkins SM, Vermolen B, Lichtensztejin D, Grotsky DA, Morgado-Palacin L, Gapud EJ, Sleckman BP, Sullivan T, Sage J, Stewart CL, Mai S, Gonzalo S. Novel roles for A-type lamins in telomere biology and the DNA damage response pathway. The Embo Journal. 28: 2414-27. PMID 19629036 DOI: 10.1038/emboj.2009.196  0.96
2009 Lin PS, McPherson LA, Chen AY, Sage J, Ford JM. The role of the retinoblastoma/E2F1 tumor suppressor pathway in the lesion recognition step of nucleotide excision repair Dna Repair. 8: 795-802. PMID 19376752 DOI: 10.1016/j.dnarep.2009.03.003  0.96
2008 Viatour P, Somervaille TC, Venkatasubrahmanyam S, Kogan S, McLaughlin ME, Weissman IL, Butte AJ, Passegué E, Sage J. Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family. Cell Stem Cell. 3: 416-28. PMID 18940733 DOI: 10.1016/j.stem.2008.07.009  0.96
2008 Burkhart DL, Viatour P, Ho VM, Sage J. GFP reporter mice for the retinoblastoma-related cell cycle regulator p107. Cell Cycle (Georgetown, Tex.). 7: 2544-52. PMID 18719374  0.96
2008 Burkhart DL, Sage J. Cellular mechanisms of tumour suppression by the retinoblastoma gene Nature Reviews Cancer. 8: 671-682. PMID 18650841 DOI: 10.1038/nrc2399  0.96
2007 Kotake Y, Cao R, Viatour P, Sage J, Zhang Y, Xiong Y. pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene. Genes & Development. 21: 49-54. PMID 17210787 DOI: 10.1101/gad.1499407  0.96
2006 Haigis K, Sage J, Glickman J, Shafer S, Jacks T. The related retinoblastoma (pRb) and p130 proteins cooperate to regulate homeostasis in the intestinal epithelium. The Journal of Biological Chemistry. 281: 638-47. PMID 16258171 DOI: 10.1074/jbc.M509053200  0.56
2004 MacPherson D, Sage J, Kim T, Ho D, McLaughlin ME, Jacks T. Cell type-specific effects of Rb deletion in the murine retina. Genes & Development. 18: 1681-94. PMID 15231717 DOI: 10.1101/gad.1203304  0.96
2004 Mayhew CN, Perkin LM, Zhang X, Sage J, Jacks T, Knudsen ES. Discrete signaling pathways participate in RB-dependent responses to chemotherapeutic agents. Oncogene. 23: 4107-20. PMID 15064736 DOI: 10.1038/sj.onc.1207503  0.56
2004 Bosco EE, Mayhew CN, Hennigan RF, Sage J, Jacks T, Knudsen ES. RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult Nucleic Acids Research. 32: 25-34. PMID 14704340 DOI: 10.1093/nar/gkg919  0.96
2003 Balsitis SJ, Sage J, Duensing S, Münger K, Jacks T, Lambert PF. Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo. Molecular and Cellular Biology. 23: 9094-103. PMID 14645521 DOI: 10.1128/MCB.23.24.9094-9103.2003  0.96
2003 Ihrie RA, Reczek E, Horner JS, Khachatrian L, Sage J, Jacks T, Attardi LD. Perp Is a Mediator of p53-Dependent Apoptosis in Diverse Cell Types Current Biology. 13: 1985-1990. PMID 14614825 DOI: 10.1016/j.cub.2003.10.055  0.96
2003 Sage J, Miller AL, Pérez-Mancera PA, Wysocki JM, Jacks T. Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature. 424: 223-8. PMID 12853964 DOI: 10.1038/nature01764  0.56
2002 Klappacher GW, Lunyak VV, Sykes DB, Sawka-Verhelle D, Sage J, Brard G, Ngo SD, Gangadharan D, Jacks T, Kamps MP, Rose DW, Rosenfeld MG, Glass CK. An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation. Cell. 109: 169-80. PMID 12007404 DOI: 10.1016/S0092-8674(02)00714-6  0.96
2002 de Vries A, Flores ER, Miranda B, Hsieh HM, van Oostrom CT, Sage J, Jacks T. Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function. Proceedings of the National Academy of Sciences of the United States of America. 99: 2948-53. PMID 11867759 DOI: 10.1073/pnas.052713099  0.96
Show low-probability matches.